Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat)) | BDBM20954 (2-(4-methoxy-2,6-dimethylphenoxy)-3,6-dimethyl-4-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Pfizer | Assay Description The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. | J Med Chem 51: 1377-84 (2008) Article DOI: 10.1021/jm070578k BindingDB Entry DOI: 10.7270/Q2F47MDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat)) | BDBM20950 (2-(4-bromo-2,6-dimethylphenoxy)-3,6-dimethyl-4-(pe...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Pfizer | Assay Description The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. | J Med Chem 51: 1377-84 (2008) Article DOI: 10.1021/jm070578k BindingDB Entry DOI: 10.7270/Q2F47MDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat)) | BDBM20959 (2-Aryloxy-4-alkoxy-pyridine, 40 | 2-[4-(methoxymet...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Pfizer | Assay Description The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. | J Med Chem 51: 1377-84 (2008) Article DOI: 10.1021/jm070578k BindingDB Entry DOI: 10.7270/Q2F47MDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat)) | BDBM20971 (2-Arylamino-4-alkyloxypyridine, 13 | 3,6-dimethyl-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Pfizer | Assay Description The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. | J Med Chem 51: 1385-92 (2008) Article DOI: 10.1021/jm070579c BindingDB Entry DOI: 10.7270/Q29C6VQ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat)) | BDBM20966 (2-Aryloxy-4-alkylaminopyridine, 3a | 3,6-dimethyl-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 5.10 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Pfizer | Assay Description The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. | J Med Chem 51: 1385-92 (2008) Article DOI: 10.1021/jm070579c BindingDB Entry DOI: 10.7270/Q29C6VQ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat)) | BDBM20949 (2-(4-chloro-2,6-dimethylphenoxy)-3,6-dimethyl-4-(p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.5 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Pfizer | Assay Description The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. | J Med Chem 51: 1377-84 (2008) Article DOI: 10.1021/jm070578k BindingDB Entry DOI: 10.7270/Q2F47MDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat)) | BDBM20968 (2-(4-bromo-2,6-dimethylphenoxy)-3,6-dimethyl-N-(pe...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.60 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Pfizer | Assay Description The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. | J Med Chem 51: 1385-92 (2008) Article DOI: 10.1021/jm070579c BindingDB Entry DOI: 10.7270/Q29C6VQ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat)) | BDBM20969 (2-Aryloxy-4-alkylaminopyridine, 5a | methyl 2-(4-c...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.40 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Pfizer | Assay Description The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. | J Med Chem 51: 1385-92 (2008) Article DOI: 10.1021/jm070579c BindingDB Entry DOI: 10.7270/Q29C6VQ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat)) | BDBM20933 (3,6-dimethyl-4-(pentan-3-yloxy)-2-(2,4,6-trimethyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6.80 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Pfizer | Assay Description The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. | J Med Chem 51: 1377-84 (2008) Article DOI: 10.1021/jm070578k BindingDB Entry DOI: 10.7270/Q2F47MDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat)) | BDBM20933 (3,6-dimethyl-4-(pentan-3-yloxy)-2-(2,4,6-trimethyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6.80 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Pfizer | Assay Description The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. | J Med Chem 51: 1385-92 (2008) Article DOI: 10.1021/jm070579c BindingDB Entry DOI: 10.7270/Q29C6VQ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat)) | BDBM20967 (2-(4-chloro-2,6-dimethylphenoxy)-3,6-dimethyl-N-(p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.20 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Pfizer | Assay Description The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. | J Med Chem 51: 1385-92 (2008) Article DOI: 10.1021/jm070579c BindingDB Entry DOI: 10.7270/Q29C6VQ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat)) | BDBM20935 (2-Aryloxy-4-alkoxy-pyridine, 16 | 3-ethyl-6-methyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 9.10 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Pfizer | Assay Description The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. | J Med Chem 51: 1377-84 (2008) Article DOI: 10.1021/jm070578k BindingDB Entry DOI: 10.7270/Q2F47MDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat)) | BDBM20941 (2-Aryloxy-4-alkoxy-pyridine, 22 | 3-bromo-6-methyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.80 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Pfizer | Assay Description The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. | J Med Chem 51: 1377-84 (2008) Article DOI: 10.1021/jm070578k BindingDB Entry DOI: 10.7270/Q2F47MDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat)) | BDBM20947 (2-(2,6-dimethyl-4-propylphenoxy)-3,6-dimethyl-4-(p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 9.80 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Pfizer | Assay Description The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. | J Med Chem 51: 1377-84 (2008) Article DOI: 10.1021/jm070578k BindingDB Entry DOI: 10.7270/Q2F47MDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat)) | BDBM20965 (2-pyridinoxy-4-alkoxy-pyridine, 14 | 3,6-dimethyl-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. | J Med Chem 51: 1377-84 (2008) Article DOI: 10.1021/jm070578k BindingDB Entry DOI: 10.7270/Q2F47MDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat)) | BDBM20962 (2-Aryloxy-4-alkoxy-pyridine, 43 | 4-[(1-methoxybut...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Pfizer | Assay Description The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. | J Med Chem 51: 1377-84 (2008) Article DOI: 10.1021/jm070578k BindingDB Entry DOI: 10.7270/Q2F47MDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat)) | BDBM20946 (2-(4-ethyl-2,6-dimethylphenoxy)-3,6-dimethyl-4-(pe...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Pfizer | Assay Description The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. | J Med Chem 51: 1377-84 (2008) Article DOI: 10.1021/jm070578k BindingDB Entry DOI: 10.7270/Q2F47MDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat)) | BDBM20939 (2-Aryloxy-4-alkoxy-pyridine, 20 | 6-methyl-4-(pent...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Pfizer | Assay Description The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. | J Med Chem 51: 1377-84 (2008) Article DOI: 10.1021/jm070578k BindingDB Entry DOI: 10.7270/Q2F47MDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat)) | BDBM20951 (2-(4-iodo-2,6-dimethylphenoxy)-3,6-dimethyl-4-(pen...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Pfizer | Assay Description The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. | J Med Chem 51: 1377-84 (2008) Article DOI: 10.1021/jm070578k BindingDB Entry DOI: 10.7270/Q2F47MDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat)) | BDBM20938 (2-Aryloxy-4-alkoxy-pyridine, 19 | 6-methyl-3-nitro...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Pfizer | Assay Description The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. | J Med Chem 51: 1377-84 (2008) Article DOI: 10.1021/jm070578k BindingDB Entry DOI: 10.7270/Q2F47MDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat)) | BDBM20964 (2-Aryloxy-4-alkoxy-pyridine, 13 | 3,6-dimethyl-4-[...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. | J Med Chem 51: 1377-84 (2008) Article DOI: 10.1021/jm070578k BindingDB Entry DOI: 10.7270/Q2F47MDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat)) | BDBM20952 (2-Aryloxy-4-alkoxy-pyridine, 33 | 4-{[3,6-dimethyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 18 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Pfizer | Assay Description The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. | J Med Chem 51: 1377-84 (2008) Article DOI: 10.1021/jm070578k BindingDB Entry DOI: 10.7270/Q2F47MDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat)) | BDBM20955 (2-(4-ethoxy-2,6-dimethylphenoxy)-3,6-dimethyl-4-(p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Pfizer | Assay Description The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. | J Med Chem 51: 1377-84 (2008) Article DOI: 10.1021/jm070578k BindingDB Entry DOI: 10.7270/Q2F47MDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat)) | BDBM20940 (2-Aryloxy-4-alkoxy-pyridine, 21 | N,N,6-trimethyl-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Pfizer | Assay Description The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. | J Med Chem 51: 1377-84 (2008) Article DOI: 10.1021/jm070578k BindingDB Entry DOI: 10.7270/Q2F47MDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat)) | BDBM20961 (2-Aryloxy-4-alkoxy-pyridine, 42 | 4-(butan-2-yloxy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Pfizer | Assay Description The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. | J Med Chem 51: 1377-84 (2008) Article DOI: 10.1021/jm070578k BindingDB Entry DOI: 10.7270/Q2F47MDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat)) | BDBM20970 (2-(4-chloro-2,6-dimethylphenoxy)-4-{[(2S)-1-hydrox...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 31 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Pfizer | Assay Description The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. | J Med Chem 51: 1385-92 (2008) Article DOI: 10.1021/jm070579c BindingDB Entry DOI: 10.7270/Q29C6VQ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat)) | BDBM20948 (2-(4-fluoro-2,6-dimethylphenoxy)-3,6-dimethyl-4-(p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 32 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Pfizer | Assay Description The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. | J Med Chem 51: 1377-84 (2008) Article DOI: 10.1021/jm070578k BindingDB Entry DOI: 10.7270/Q2F47MDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat)) | BDBM20960 (2-(4-{[3,6-dimethyl-4-(pentan-3-yloxy)pyridin-2-yl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Pfizer | Assay Description The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. | J Med Chem 51: 1377-84 (2008) Article DOI: 10.1021/jm070578k BindingDB Entry DOI: 10.7270/Q2F47MDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat)) | BDBM20957 (2-Aryloxy-4-alkoxy-pyridine, 38 | 4-{[3,6-dimethyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Pfizer | Assay Description The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. | J Med Chem 51: 1377-84 (2008) Article DOI: 10.1021/jm070578k BindingDB Entry DOI: 10.7270/Q2F47MDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat)) | BDBM20958 ((4-{[3,6-dimethyl-4-(pentan-3-yloxy)pyridin-2-yl]o...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 61 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Pfizer | Assay Description The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. | J Med Chem 51: 1377-84 (2008) Article DOI: 10.1021/jm070578k BindingDB Entry DOI: 10.7270/Q2F47MDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat)) | BDBM20934 (2-Aryloxy-4-alkoxy-pyridine, 15 | 6-ethyl-3-methyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 86 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Pfizer | Assay Description The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. | J Med Chem 51: 1377-84 (2008) Article DOI: 10.1021/jm070578k BindingDB Entry DOI: 10.7270/Q2F47MDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat)) | BDBM20963 (2-Aryloxy-4-alkoxy-pyridine, 44 | 3,6-Dimethyl-4-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer | Assay Description The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. | J Med Chem 51: 1377-84 (2008) Article DOI: 10.1021/jm070578k BindingDB Entry DOI: 10.7270/Q2F47MDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat)) | BDBM20956 (2-Aryloxy-4-alkoxy-pyridine, 37 | 2-[2,6-dimethyl-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 110 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Pfizer | Assay Description The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. | J Med Chem 51: 1377-84 (2008) Article DOI: 10.1021/jm070578k BindingDB Entry DOI: 10.7270/Q2F47MDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat)) | BDBM20945 (2-(2,6-dimethylphenoxy)-3,6-dimethyl-4-(pentan-3-y...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 110 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Pfizer | Assay Description The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. | J Med Chem 51: 1377-84 (2008) Article DOI: 10.1021/jm070578k BindingDB Entry DOI: 10.7270/Q2F47MDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat)) | BDBM20936 (2-Aryloxy-4-alkoxy-pyridine, 17 | 2-methyl-4-(pent...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 150 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Pfizer | Assay Description The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. | J Med Chem 51: 1377-84 (2008) Article DOI: 10.1021/jm070578k BindingDB Entry DOI: 10.7270/Q2F47MDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat)) | BDBM20943 (2,3,5-trimethyl-4-(pentan-3-yloxy)-6-(2,4,6-trimet...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 180 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Pfizer | Assay Description The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. | J Med Chem 51: 1377-84 (2008) Article DOI: 10.1021/jm070578k BindingDB Entry DOI: 10.7270/Q2F47MDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat)) | BDBM20937 (2-Aryloxy-4-alkoxy-pyridine, 18 | methyl 6-methyl-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 470 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Pfizer | Assay Description The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. | J Med Chem 51: 1377-84 (2008) Article DOI: 10.1021/jm070578k BindingDB Entry DOI: 10.7270/Q2F47MDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat)) | BDBM20972 (2,4-diaminopyridine, 16 | 3,6-dimethyl-4-N-(pentan...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 750 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Pfizer | Assay Description The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. | J Med Chem 51: 1385-92 (2008) Article DOI: 10.1021/jm070579c BindingDB Entry DOI: 10.7270/Q29C6VQ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat)) | BDBM20953 (2-Aryloxy-4-alkoxy-pyridine, 34 | 4-{[3,6-dimethyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Pfizer | Assay Description The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. | J Med Chem 51: 1377-84 (2008) Article DOI: 10.1021/jm070578k BindingDB Entry DOI: 10.7270/Q2F47MDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat)) | BDBM20942 (2-Aryloxy-4-alkoxy-pyridine, 23 | 6-methyl-4-(pent...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Pfizer | Assay Description The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. | J Med Chem 51: 1377-84 (2008) Article DOI: 10.1021/jm070578k BindingDB Entry DOI: 10.7270/Q2F47MDH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Corticotropin-releasing factor receptor 1 (Rattus norvegicus (rat)) | BDBM20944 (2-Aryloxy-4-alkoxy-pyridine, 25 | 3-ethyl-2,5-dime...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | 7.0 | 22 |
Pfizer | Assay Description The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. | J Med Chem 51: 1377-84 (2008) Article DOI: 10.1021/jm070578k BindingDB Entry DOI: 10.7270/Q2F47MDH | |||||||||||
More data for this Ligand-Target Pair |