Compile Data Set for Download or QSAR

Found 24 hits with Last Name = 'frank' and Initial = 'ka'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM19992 (2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methy...) Show SMILES OC(=O)Cc1cccc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2Cl)C(F)(F)F)c1 Show InChI InChI=1S/C33H31ClF3NO3/c34-32-27(15-8-17-30(32)33(35,36)37)22-38(18-9-19-41-28-16-7-10-24(20-28)21-31(39)40)23-29(25-11-3-1-4-12-25)26-13-5-2-6-14-26/h1-8,10-17,20,29H,9,18-19,21-23H2,(H,39,40)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	175	n/a	n/a	7.5	22
GSK					Assay Description The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...				Bioorg Med Chem Lett 19: 1097-100 (2009) Article DOI: 10.1016/j.bmcl.2009.01.004 BindingDB Entry DOI: 10.7270/Q28W3BMD
					More data for this Ligand-Target Pair				3D Structure (crystal)
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM27174 (1H-indol-1-yl tertiary amine, 18 | 2-{4-[3-({[2-ch...) Show SMILES OC(=O)Cn1ccc2c(OCCCN(CC(c3ccccc3)c3ccccc3)Cc3cccc(c3Cl)C(F)(F)F)cccc12 Show InChI InChI=1S/C35H32ClF3N2O3/c36-34-27(14-7-15-30(34)35(37,38)39)22-40(23-29(25-10-3-1-4-11-25)26-12-5-2-6-13-26)19-9-21-44-32-17-8-16-31-28(32)18-20-41(31)24-33(42)43/h1-8,10-18,20,29H,9,19,21-24H2,(H,42,43)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4	n/a	n/a	7.5	22
GSK					Assay Description The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...				Bioorg Med Chem Lett 19: 1097-100 (2009) Article DOI: 10.1016/j.bmcl.2009.01.004 BindingDB Entry DOI: 10.7270/Q28W3BMD
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM27165 (1H-indol-1-yl tertiary amine, 9 | methyl 3-[3-({[2...) Show SMILES COC(=O)c1cc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2Cl)C(F)(F)F)no1 Show InChI InChI=1S/C30H28ClF3N2O4/c1-38-29(37)26-18-27(35-40-26)39-17-9-16-36(19-23-14-8-15-25(28(23)31)30(32,33)34)20-24(21-10-4-2-5-11-21)22-12-6-3-7-13-22/h2-8,10-15,18,24H,9,16-17,19-20H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	63	n/a	n/a	7.5	22
GSK					Assay Description The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...				Bioorg Med Chem Lett 19: 1097-100 (2009) Article DOI: 10.1016/j.bmcl.2009.01.004 BindingDB Entry DOI: 10.7270/Q28W3BMD
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM27166 (1H-indol-1-yl tertiary amine, 10 | {[2-chloro-3-(t...) Show SMILES FC(F)(F)c1cccc(CN(CCCOc2n[nH]c3ccccc23)CC(c2ccccc2)c2ccccc2)c1Cl Show InChI InChI=1S/C32H29ClF3N3O/c33-30-25(15-9-17-28(30)32(34,35)36)21-39(19-10-20-40-31-26-16-7-8-18-29(26)37-38-31)22-27(23-11-3-1-4-12-23)24-13-5-2-6-14-24/h1-9,11-18,27H,10,19-22H2,(H,37,38)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	110	n/a	n/a	7.5	22
GSK					Assay Description The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...				Bioorg Med Chem Lett 19: 1097-100 (2009) Article DOI: 10.1016/j.bmcl.2009.01.004 BindingDB Entry DOI: 10.7270/Q28W3BMD
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM27167 (1H-indol-1-yl tertiary amine, 11 | {[2-chloro-3-(t...) Show SMILES Cc1cc(C)c2c(OCCCN(CC(c3ccccc3)c3ccccc3)Cc3cccc(c3Cl)C(F)(F)F)n[nH]c2n1 Show InChI InChI=1S/C33H32ClF3N4O/c1-22-19-23(2)38-31-29(22)32(40-39-31)42-18-10-17-41(20-26-15-9-16-28(30(26)34)33(35,36)37)21-27(24-11-5-3-6-12-24)25-13-7-4-8-14-25/h3-9,11-16,19,27H,10,17-18,20-21H2,1-2H3,(H,38,39,40)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+3	n/a	n/a	7.5	22
GSK					Assay Description The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...				Bioorg Med Chem Lett 19: 1097-100 (2009) Article DOI: 10.1016/j.bmcl.2009.01.004 BindingDB Entry DOI: 10.7270/Q28W3BMD
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM27168 (1H-indol-1-yl tertiary amine, 12 | {[2-chloro-3-(t...) Show SMILES Cc1cc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2Cl)C(F)(F)F)n2ncnc2n1 Show InChI InChI=1S/C31H29ClF3N5O/c1-22-18-28(40-30(38-22)36-21-37-40)41-17-9-16-39(19-25-14-8-15-27(29(25)32)31(33,34)35)20-26(23-10-4-2-5-11-23)24-12-6-3-7-13-24/h2-8,10-15,18,21,26H,9,16-17,19-20H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	790	n/a	n/a	7.5	22
GSK					Assay Description The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...				Bioorg Med Chem Lett 19: 1097-100 (2009) Article DOI: 10.1016/j.bmcl.2009.01.004 BindingDB Entry DOI: 10.7270/Q28W3BMD
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM27169 (1H-indol-1-yl tertiary amine, 13 | methyl 2-{5-[3-...) Show SMILES COC(=O)Cc1c[nH]c2ccc(OCCCN(CC(c3ccccc3)c3ccccc3)Cc3cccc(c3Cl)C(F)(F)F)cc12 Show InChI InChI=1S/C36H34ClF3N2O3/c1-44-34(43)20-28-22-41-33-17-16-29(21-30(28)33)45-19-9-18-42(23-27-14-8-15-32(35(27)37)36(38,39)40)24-31(25-10-4-2-5-11-25)26-12-6-3-7-13-26/h2-8,10-17,21-22,31,41H,9,18-20,23-24H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	630	n/a	n/a	7.5	22
GSK					Assay Description The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...				Bioorg Med Chem Lett 19: 1097-100 (2009) Article DOI: 10.1016/j.bmcl.2009.01.004 BindingDB Entry DOI: 10.7270/Q28W3BMD
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM27170 (1H-indol-1-yl tertiary amine, 14 | {[2-chloro-3-(t...) Show SMILES FC(F)(F)c1cccc(CN(CCCOc2ccc3[nH]ccc3c2)CC(c2ccccc2)c2ccccc2)c1Cl Show InChI InChI=1S/C33H30ClF3N2O/c34-32-27(13-7-14-30(32)33(35,36)37)22-39(19-8-20-40-28-15-16-31-26(21-28)17-18-38-31)23-29(24-9-3-1-4-10-24)25-11-5-2-6-12-25/h1-7,9-18,21,29,38H,8,19-20,22-23H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	226	n/a	n/a	7.5	22
GSK					Assay Description The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...				Bioorg Med Chem Lett 19: 1097-100 (2009) Article DOI: 10.1016/j.bmcl.2009.01.004 BindingDB Entry DOI: 10.7270/Q28W3BMD
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM27171 (1H-indol-1-yl tertiary amine, 15 | {[2-chloro-3-(t...) Show SMILES FC(F)(F)c1cccc(CN(CCCOc2cccc3[nH]ccc23)CC(c2ccccc2)c2ccccc2)c1Cl Show InChI InChI=1S/C33H30ClF3N2O/c34-32-26(14-7-15-29(32)33(35,36)37)22-39(20-9-21-40-31-17-8-16-30-27(31)18-19-38-30)23-28(24-10-3-1-4-11-24)25-12-5-2-6-13-25/h1-8,10-19,28,38H,9,20-23H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	60	n/a	n/a	7.5	22
GSK					Assay Description The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...				Bioorg Med Chem Lett 19: 1097-100 (2009) Article DOI: 10.1016/j.bmcl.2009.01.004 BindingDB Entry DOI: 10.7270/Q28W3BMD
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM27172 (1H-indol-1-yl tertiary amine, 16 | {[2-chloro-3-(t...) Show SMILES Cn1ccc2c(OCCCN(CC(c3ccccc3)c3ccccc3)Cc3cccc(c3Cl)C(F)(F)F)cccc12 Show InChI InChI=1S/C34H32ClF3N2O/c1-39-21-19-28-31(39)17-9-18-32(28)41-22-10-20-40(23-27-15-8-16-30(33(27)35)34(36,37)38)24-29(25-11-4-2-5-12-25)26-13-6-3-7-14-26/h2-9,11-19,21,29H,10,20,22-24H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	39	n/a	n/a	7.5	22
GSK					Assay Description The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...				Bioorg Med Chem Lett 19: 1097-100 (2009) Article DOI: 10.1016/j.bmcl.2009.01.004 BindingDB Entry DOI: 10.7270/Q28W3BMD
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM27173 (1H-indol-1-yl tertiary amine, 17 | {[2-chloro-3-(t...) Show SMILES CS(=O)(=O)n1ccc2c(OCCCN(CC(c3ccccc3)c3ccccc3)Cc3cccc(c3Cl)C(F)(F)F)cccc12 Show InChI InChI=1S/C34H32ClF3N2O3S/c1-44(41,42)40-21-19-28-31(40)17-9-18-32(28)43-22-10-20-39(23-27-15-8-16-30(33(27)35)34(36,37)38)24-29(25-11-4-2-5-12-25)26-13-6-3-7-14-26/h2-9,11-19,21,29H,10,20,22-24H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	7.5	22
GSK					Assay Description The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...				Bioorg Med Chem Lett 19: 1097-100 (2009) Article DOI: 10.1016/j.bmcl.2009.01.004 BindingDB Entry DOI: 10.7270/Q28W3BMD
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM27174 (1H-indol-1-yl tertiary amine, 18 | 2-{4-[3-({[2-ch...) Show SMILES OC(=O)Cn1ccc2c(OCCCN(CC(c3ccccc3)c3ccccc3)Cc3cccc(c3Cl)C(F)(F)F)cccc12 Show InChI InChI=1S/C35H32ClF3N2O3/c36-34-27(14-7-15-30(34)35(37,38)39)22-40(23-29(25-10-3-1-4-11-25)26-12-5-2-6-13-26)19-9-21-44-32-17-8-16-31-28(32)18-20-41(31)24-33(42)43/h1-8,10-18,20,29H,9,19,21-24H2,(H,42,43)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	14	n/a	n/a	7.5	22
GSK					Assay Description The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...				Bioorg Med Chem Lett 19: 1097-100 (2009) Article DOI: 10.1016/j.bmcl.2009.01.004 BindingDB Entry DOI: 10.7270/Q28W3BMD
					More data for this Ligand-Target Pair				3D Structure (crystal)
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM19992 (2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methy...) Show SMILES OC(=O)Cc1cccc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2Cl)C(F)(F)F)c1 Show InChI InChI=1S/C33H31ClF3NO3/c34-32-27(15-8-17-30(32)33(35,36)37)22-38(18-9-19-41-28-16-7-10-24(20-28)21-31(39)40)23-29(25-11-3-1-4-12-25)26-13-5-2-6-14-26/h1-8,10-17,20,29H,9,18-19,21-23H2,(H,39,40)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	25	n/a	n/a	7.5	22
GSK					Assay Description The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...				Bioorg Med Chem Lett 19: 1097-100 (2009) Article DOI: 10.1016/j.bmcl.2009.01.004 BindingDB Entry DOI: 10.7270/Q28W3BMD
					More data for this Ligand-Target Pair				3D Structure (crystal)
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM27164 (1H-indol-1-yl tertiary amine, 8 | {[2-chloro-3-(tr...) Show SMILES Cc1cc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2Cl)C(F)(F)F)[nH]n1 Show InChI InChI=1S/C29H29ClF3N3O/c1-21-18-27(35-34-21)37-17-9-16-36(19-24-14-8-15-26(28(24)30)29(31,32)33)20-25(22-10-4-2-5-11-22)23-12-6-3-7-13-23/h2-8,10-15,18,25H,9,16-17,19-20H2,1H3,(H,34,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	7.5	22
GSK					Assay Description The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...				Bioorg Med Chem Lett 19: 1097-100 (2009) Article DOI: 10.1016/j.bmcl.2009.01.004 BindingDB Entry DOI: 10.7270/Q28W3BMD
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM27165 (1H-indol-1-yl tertiary amine, 9 | methyl 3-[3-({[2...) Show SMILES COC(=O)c1cc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2Cl)C(F)(F)F)no1 Show InChI InChI=1S/C30H28ClF3N2O4/c1-38-29(37)26-18-27(35-40-26)39-17-9-16-36(19-23-14-8-15-25(28(23)31)30(32,33)34)20-24(21-10-4-2-5-11-21)22-12-6-3-7-13-22/h2-8,10-15,18,24H,9,16-17,19-20H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	26	n/a	n/a	7.5	22
GSK					Assay Description The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...				Bioorg Med Chem Lett 19: 1097-100 (2009) Article DOI: 10.1016/j.bmcl.2009.01.004 BindingDB Entry DOI: 10.7270/Q28W3BMD
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM27166 (1H-indol-1-yl tertiary amine, 10 | {[2-chloro-3-(t...) Show SMILES FC(F)(F)c1cccc(CN(CCCOc2n[nH]c3ccccc23)CC(c2ccccc2)c2ccccc2)c1Cl Show InChI InChI=1S/C32H29ClF3N3O/c33-30-25(15-9-17-28(30)32(34,35)36)21-39(19-10-20-40-31-26-16-7-8-18-29(26)37-38-31)22-27(23-11-3-1-4-12-23)24-13-5-2-6-14-24/h1-9,11-18,27H,10,19-22H2,(H,37,38)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	60	n/a	n/a	7.5	22
GSK					Assay Description The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...				Bioorg Med Chem Lett 19: 1097-100 (2009) Article DOI: 10.1016/j.bmcl.2009.01.004 BindingDB Entry DOI: 10.7270/Q28W3BMD
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM27167 (1H-indol-1-yl tertiary amine, 11 | {[2-chloro-3-(t...) Show SMILES Cc1cc(C)c2c(OCCCN(CC(c3ccccc3)c3ccccc3)Cc3cccc(c3Cl)C(F)(F)F)n[nH]c2n1 Show InChI InChI=1S/C33H32ClF3N4O/c1-22-19-23(2)38-31-29(22)32(40-39-31)42-18-10-17-41(20-26-15-9-16-28(30(26)34)33(35,36)37)21-27(24-11-5-3-6-12-24)25-13-7-4-8-14-25/h3-9,11-16,19,27H,10,17-18,20-21H2,1-2H3,(H,38,39,40)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	510	n/a	n/a	7.5	22
GSK					Assay Description The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...				Bioorg Med Chem Lett 19: 1097-100 (2009) Article DOI: 10.1016/j.bmcl.2009.01.004 BindingDB Entry DOI: 10.7270/Q28W3BMD
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM27168 (1H-indol-1-yl tertiary amine, 12 | {[2-chloro-3-(t...) Show SMILES Cc1cc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2Cl)C(F)(F)F)n2ncnc2n1 Show InChI InChI=1S/C31H29ClF3N5O/c1-22-18-28(40-30(38-22)36-21-37-40)41-17-9-16-39(19-25-14-8-15-27(29(25)32)31(33,34)35)20-26(23-10-4-2-5-11-23)24-12-6-3-7-13-24/h2-8,10-15,18,21,26H,9,16-17,19-20H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	560	n/a	n/a	7.5	22
GSK					Assay Description The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...				Bioorg Med Chem Lett 19: 1097-100 (2009) Article DOI: 10.1016/j.bmcl.2009.01.004 BindingDB Entry DOI: 10.7270/Q28W3BMD
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM27169 (1H-indol-1-yl tertiary amine, 13 | methyl 2-{5-[3-...) Show SMILES COC(=O)Cc1c[nH]c2ccc(OCCCN(CC(c3ccccc3)c3ccccc3)Cc3cccc(c3Cl)C(F)(F)F)cc12 Show InChI InChI=1S/C36H34ClF3N2O3/c1-44-34(43)20-28-22-41-33-17-16-29(21-30(28)33)45-19-9-18-42(23-27-14-8-15-32(35(27)37)36(38,39)40)24-31(25-10-4-2-5-11-25)26-12-6-3-7-13-26/h2-8,10-17,21-22,31,41H,9,18-20,23-24H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	288	n/a	n/a	7.5	22
GSK					Assay Description The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...				Bioorg Med Chem Lett 19: 1097-100 (2009) Article DOI: 10.1016/j.bmcl.2009.01.004 BindingDB Entry DOI: 10.7270/Q28W3BMD
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM27170 (1H-indol-1-yl tertiary amine, 14 | {[2-chloro-3-(t...) Show SMILES FC(F)(F)c1cccc(CN(CCCOc2ccc3[nH]ccc3c2)CC(c2ccccc2)c2ccccc2)c1Cl Show InChI InChI=1S/C33H30ClF3N2O/c34-32-27(13-7-14-30(32)33(35,36)37)22-39(19-8-20-40-28-15-16-31-26(21-28)17-18-38-31)23-29(24-9-3-1-4-10-24)25-11-5-2-6-12-25/h1-7,9-18,21,29,38H,8,19-20,22-23H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	23	n/a	n/a	7.5	22
GSK					Assay Description The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...				Bioorg Med Chem Lett 19: 1097-100 (2009) Article DOI: 10.1016/j.bmcl.2009.01.004 BindingDB Entry DOI: 10.7270/Q28W3BMD
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM27171 (1H-indol-1-yl tertiary amine, 15 | {[2-chloro-3-(t...) Show SMILES FC(F)(F)c1cccc(CN(CCCOc2cccc3[nH]ccc23)CC(c2ccccc2)c2ccccc2)c1Cl Show InChI InChI=1S/C33H30ClF3N2O/c34-32-26(14-7-15-29(32)33(35,36)37)22-39(20-9-21-40-31-17-8-16-30-27(31)18-19-38-30)23-28(24-10-3-1-4-11-24)25-12-5-2-6-13-25/h1-8,10-19,28,38H,9,20-23H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	7.5	22
GSK					Assay Description The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...				Bioorg Med Chem Lett 19: 1097-100 (2009) Article DOI: 10.1016/j.bmcl.2009.01.004 BindingDB Entry DOI: 10.7270/Q28W3BMD
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM27172 (1H-indol-1-yl tertiary amine, 16 | {[2-chloro-3-(t...) Show SMILES Cn1ccc2c(OCCCN(CC(c3ccccc3)c3ccccc3)Cc3cccc(c3Cl)C(F)(F)F)cccc12 Show InChI InChI=1S/C34H32ClF3N2O/c1-39-21-19-28-31(39)17-9-18-32(28)41-22-10-20-40(23-27-15-8-16-30(33(27)35)34(36,37)38)24-29(25-11-4-2-5-12-25)26-13-6-3-7-14-26/h2-9,11-19,21,29H,10,20,22-24H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	12	n/a	n/a	7.5	22
GSK					Assay Description The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...				Bioorg Med Chem Lett 19: 1097-100 (2009) Article DOI: 10.1016/j.bmcl.2009.01.004 BindingDB Entry DOI: 10.7270/Q28W3BMD
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM27173 (1H-indol-1-yl tertiary amine, 17 | {[2-chloro-3-(t...) Show SMILES CS(=O)(=O)n1ccc2c(OCCCN(CC(c3ccccc3)c3ccccc3)Cc3cccc(c3Cl)C(F)(F)F)cccc12 Show InChI InChI=1S/C34H32ClF3N2O3S/c1-44(41,42)40-21-19-28-31(40)17-9-18-32(28)43-22-10-20-39(23-27-15-8-16-30(33(27)35)34(36,37)38)24-29(25-11-4-2-5-12-25)26-13-6-3-7-14-26/h2-9,11-19,21,29H,10,20,22-24H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	7	n/a	n/a	7.5	22
GSK					Assay Description The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...				Bioorg Med Chem Lett 19: 1097-100 (2009) Article DOI: 10.1016/j.bmcl.2009.01.004 BindingDB Entry DOI: 10.7270/Q28W3BMD
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM27164 (1H-indol-1-yl tertiary amine, 8 | {[2-chloro-3-(tr...) Show SMILES Cc1cc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2Cl)C(F)(F)F)[nH]n1 Show InChI InChI=1S/C29H29ClF3N3O/c1-21-18-27(35-34-21)37-17-9-16-36(19-24-14-8-15-26(28(24)30)29(31,32)33)20-25(22-10-4-2-5-11-22)23-12-6-3-7-13-23/h2-8,10-15,18,25H,9,16-17,19-20H2,1H3,(H,34,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	23	n/a	n/a	7.5	22
GSK					Assay Description The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...				Bioorg Med Chem Lett 19: 1097-100 (2009) Article DOI: 10.1016/j.bmcl.2009.01.004 BindingDB Entry DOI: 10.7270/Q28W3BMD
					More data for this Ligand-Target Pair