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Compile Data Set for Download or QSAR

Found 74 hits with Last Name = 'fricks' and Initial = 'i'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
P2Y purinoceptor 14


(Homo sapiens (Human))
BDBM50197974
PNG
(udp-N-acetyl-glucosamine)
Show SMILES CC(=O)N[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1OP([O-])(=O)OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O
Show InChI InChI=1S/C17H27N3O17P2/c1-6(22)18-10-13(26)11(24)7(4-21)35-16(10)36-39(31,32)37-38(29,30)33-5-8-12(25)14(27)15(34-8)20-3-2-9(23)19-17(20)28/h2-3,7-8,10-16,21,24-27H,4-5H2,1H3,(H,18,22)(H,29,30)(H,31,32)(H,19,23,28)/p-2/t7-,8+,10-,11-,12+,13-,14+,15+,16-/m0/s1
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n/an/an/an/a 810n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y14 expressed in COS7 cells assessed as stimulation of PLC-mediated [3H]inositol hydrolsis


J Med Chem 50: 2030-9 (2007)


Article DOI: 10.1021/jm061222w
BindingDB Entry DOI: 10.7270/Q24Q7TPN
More data for this
Ligand-Target Pair
P2Y purinoceptor 14


(Homo sapiens (Human))
BDBM50197974
PNG
(udp-N-acetyl-glucosamine)
Show SMILES CC(=O)N[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1OP([O-])(=O)OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O
Show InChI InChI=1S/C17H27N3O17P2/c1-6(22)18-10-13(26)11(24)7(4-21)35-16(10)36-39(31,32)37-38(29,30)33-5-8-12(25)14(27)15(34-8)20-3-2-9(23)19-17(20)28/h2-3,7-8,10-16,21,24-27H,4-5H2,1H3,(H,18,22)(H,29,30)(H,31,32)(H,19,23,28)/p-2/t7-,8+,10-,11-,12+,13-,14+,15+,16-/m0/s1
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n/an/an/an/a 810n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y14 expressed in COS7 cells assessed as stimulation of PLC-mediated [3H]inositol hydrolsis


J Med Chem 50: 2030-9 (2007)


Article DOI: 10.1021/jm061222w
BindingDB Entry DOI: 10.7270/Q24Q7TPN
More data for this
Ligand-Target Pair
P2Y purinoceptor 14


(Homo sapiens (Human))
BDBM50423218
PNG
(5''-Diphosphoglucose | UDPG | URIDINE DIPHOSPHATE ...)
Show SMILES OC[C@H]1O[C@H](O[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)[C@H](O)[C@@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C15H24N2O17P2/c18-3-5-8(20)10(22)12(24)14(32-5)33-36(28,29)34-35(26,27)30-4-6-9(21)11(23)13(31-6)17-2-1-7(19)16-15(17)25/h1-2,5-6,8-14,18,20-24H,3-4H2,(H,26,27)(H,28,29)(H,16,19,25)/t5-,6-,8-,9-,10+,11-,12-,13-,14-/m1/s1
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n/an/an/an/a 354n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y14 receptor expressed in COS7 cells assessed as stimulation of PLC


Bioorg Med Chem Lett 17: 761-6 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.081
BindingDB Entry DOI: 10.7270/Q2KW5GW6
More data for this
Ligand-Target Pair
P2Y purinoceptor 14


(Homo sapiens (Human))
BDBM50197974
PNG
(udp-N-acetyl-glucosamine)
Show SMILES CC(=O)N[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1OP([O-])(=O)OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O
Show InChI InChI=1S/C17H27N3O17P2/c1-6(22)18-10-13(26)11(24)7(4-21)35-16(10)36-39(31,32)37-38(29,30)33-5-8-12(25)14(27)15(34-8)20-3-2-9(23)19-17(20)28/h2-3,7-8,10-16,21,24-27H,4-5H2,1H3,(H,18,22)(H,29,30)(H,31,32)(H,19,23,28)/p-2/t7-,8+,10-,11-,12+,13-,14+,15+,16-/m0/s1
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n/an/an/an/a 4.38E+3n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y14 receptor expressed in human COS7 cells


Bioorg Med Chem 17: 5298-311 (2009)


Article DOI: 10.1016/j.bmc.2009.05.024
BindingDB Entry DOI: 10.7270/Q28052Q7
More data for this
Ligand-Target Pair
P2Y purinoceptor 2


(Homo sapiens (Human))
BDBM50209659
PNG
(UDP-alpha-D-glucose | uridine 5'-[3-alpha-D-glucop...)
Show SMILES OC[C@H]1O[C@H](OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C15H24N2O17P2/c18-3-5-8(20)10(22)12(24)14(32-5)33-36(28,29)34-35(26,27)30-4-6-9(21)11(23)13(31-6)17-2-1-7(19)16-15(17)25/h1-2,5-6,8-14,18,20-24H,3-4H2,(H,26,27)(H,28,29)(H,16,19,25)/t5-,6-,8-,9-,10+,11-,12-,13-,14-/m1/s1
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n/an/an/an/a 1.00E+4n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y2 receptor expressed in human 1321N1 cells


Bioorg Med Chem 17: 5298-311 (2009)


Article DOI: 10.1016/j.bmc.2009.05.024
BindingDB Entry DOI: 10.7270/Q28052Q7
More data for this
Ligand-Target Pair
P2Y purinoceptor 14


(Homo sapiens (Human))
BDBM50197974
PNG
(udp-N-acetyl-glucosamine)
Show SMILES CC(=O)N[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1OP([O-])(=O)OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O
Show InChI InChI=1S/C17H27N3O17P2/c1-6(22)18-10-13(26)11(24)7(4-21)35-16(10)36-39(31,32)37-38(29,30)33-5-8-12(25)14(27)15(34-8)20-3-2-9(23)19-17(20)28/h2-3,7-8,10-16,21,24-27H,4-5H2,1H3,(H,18,22)(H,29,30)(H,31,32)(H,19,23,28)/p-2/t7-,8+,10-,11-,12+,13-,14+,15+,16-/m0/s1
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n/an/an/an/a 4.38E+3n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y14 receptor expressed in human COS7 cells


Bioorg Med Chem 17: 5298-311 (2009)


Article DOI: 10.1016/j.bmc.2009.05.024
BindingDB Entry DOI: 10.7270/Q28052Q7
More data for this
Ligand-Target Pair
P2Y purinoceptor 14


(Homo sapiens (Human))
BDBM50209658
PNG
(CHEMBL390160 | [({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,...)
Show SMILES O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)O[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O
Show InChI InChI=1S/C15H24N2O17P2/c18-5-1-2-17(15(26)16-5)14-12(25)6(19)4(32-14)3-31-35(27,28)34-36(29,30)33-13-10(23)8(21)7(20)9(22)11(13)24/h1-2,4,6-14,19-25H,3H2,(H,27,28)(H,29,30)(H,16,18,26)/t4-,6-,7-,8-,9+,10+,11-,12-,13-,14-/m1/s1
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n/an/an/an/a 1.88E+3n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y14 expressed in COS7 cells assessed as stimulation of PLC-mediated [3H]inositol hydrolsis


J Med Chem 50: 2030-9 (2007)


Article DOI: 10.1021/jm061222w
BindingDB Entry DOI: 10.7270/Q24Q7TPN
More data for this
Ligand-Target Pair
P2Y purinoceptor 14


(Homo sapiens (Human))
BDBM50209659
PNG
(UDP-alpha-D-glucose | uridine 5'-[3-alpha-D-glucop...)
Show SMILES OC[C@H]1O[C@H](OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C15H24N2O17P2/c18-3-5-8(20)10(22)12(24)14(32-5)33-36(28,29)34-35(26,27)30-4-6-9(21)11(23)13(31-6)17-2-1-7(19)16-15(17)25/h1-2,5-6,8-14,18,20-24H,3-4H2,(H,26,27)(H,28,29)(H,16,19,25)/t5-,6-,8-,9-,10+,11-,12-,13-,14-/m1/s1
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n/an/an/an/a 350n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y14 expressed in COS7 cells assessed as stimulation of PLC-mediated [3H]inositol hydrolsis


J Med Chem 50: 2030-9 (2007)


Article DOI: 10.1021/jm061222w
BindingDB Entry DOI: 10.7270/Q24Q7TPN
More data for this
Ligand-Target Pair
P2Y purinoceptor 14


(Homo sapiens (Human))
BDBM50209661
PNG
(CHEMBL226713 | [({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,...)
Show SMILES OC[C@H]1O[C@](O)(COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C15H24N2O17P2/c18-3-6-10(21)12(23)15(25,33-6)5-31-36(28,29)34-35(26,27)30-4-7-9(20)11(22)13(32-7)17-2-1-8(19)16-14(17)24/h1-2,6-7,9-13,18,20-23,25H,3-5H2,(H,26,27)(H,28,29)(H,16,19,24)/t6-,7-,9-,10-,11-,12+,13-,15-/m1/s1
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n/an/an/an/a 880n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y14 expressed in COS7 cells assessed as stimulation of PLC-mediated [3H]inositol hydrolsis


J Med Chem 50: 2030-9 (2007)


Article DOI: 10.1021/jm061222w
BindingDB Entry DOI: 10.7270/Q24Q7TPN
More data for this
Ligand-Target Pair
P2Y purinoceptor 14


(Homo sapiens (Human))
BDBM50209663
PNG
(CHEMBL374384 | MRS-2670 | diphosphoric acid 1-alph...)
Show SMILES OC[C@H]1O[C@H](OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=S)[nH]c2=O)[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C15H24N2O16P2S/c18-3-5-8(19)10(21)12(23)14(31-5)32-35(27,28)33-34(25,26)29-4-6-9(20)11(22)13(30-6)17-2-1-7(36)16-15(17)24/h1-2,5-6,8-14,18-23H,3-4H2,(H,25,26)(H,27,28)(H,16,24,36)/t5-,6-,8-,9-,10+,11-,12-,13-,14-/m1/s1
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n/an/an/an/a 350n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y14 expressed in COS7 cells assessed as stimulation of PLC-mediated [3H]inositol hydrolsis


J Med Chem 50: 2030-9 (2007)


Article DOI: 10.1021/jm061222w
BindingDB Entry DOI: 10.7270/Q24Q7TPN
More data for this
Ligand-Target Pair
P2Y purinoceptor 14


(Homo sapiens (Human))
BDBM50209665
PNG
(CHEMBL228057 | UDP-alpha-D-glucuronic acid | uridi...)
Show SMILES O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)O[C@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)C(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O
Show InChI InChI=1S/C15H22N2O18P2/c18-5-1-2-17(15(26)16-5)12-9(22)6(19)4(32-12)3-31-36(27,28)35-37(29,30)34-14-10(23)7(20)8(21)11(33-14)13(24)25/h1-2,4,6-12,14,19-23H,3H2,(H,24,25)(H,27,28)(H,29,30)(H,16,18,26)/t4-,6-,7+,8+,9-,10-,11+,12-,14-/m1/s1
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n/an/an/an/a 370n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y14 expressed in COS7 cells assessed as stimulation of PLC-mediated [3H]inositol hydrolsis


J Med Chem 50: 2030-9 (2007)


Article DOI: 10.1021/jm061222w
BindingDB Entry DOI: 10.7270/Q24Q7TPN
More data for this
Ligand-Target Pair
P2Y purinoceptor 14


(Homo sapiens (Human))
BDBM50209664
PNG
(CHEMBL439378 | diphosphoric acid 1-alpha-D-glucopy...)
Show SMILES CSC1NC(=O)N(C=C1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@H]1O |c:7|
Show InChI InChI=1S/C16H28N2O16P2S/c1-37-8-2-3-18(16(25)17-8)14-12(23)10(21)7(31-14)5-30-35(26,27)34-36(28,29)33-15-13(24)11(22)9(20)6(4-19)32-15/h2-3,6-15,19-24H,4-5H2,1H3,(H,17,25)(H,26,27)(H,28,29)/t6-,7-,8?,9-,10-,11+,12-,13-,14-,15-/m1/s1
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n/an/an/an/a>1.00E+4n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y14 expressed in COS7 cells assessed as stimulation of PLC-mediated [3H]inositol hydrolsis


J Med Chem 50: 2030-9 (2007)


Article DOI: 10.1021/jm061222w
BindingDB Entry DOI: 10.7270/Q24Q7TPN
More data for this
Ligand-Target Pair
P2Y purinoceptor 14


(Homo sapiens (Human))
BDBM50209666
PNG
(CHEMBL227711 | URIDINE-5'-DIPHOSPHATE-MANNOSE)
Show SMILES OC[C@H]1O[C@H](OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)[C@@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C15H24N2O17P2/c18-3-5-8(20)10(22)12(24)14(32-5)33-36(28,29)34-35(26,27)30-4-6-9(21)11(23)13(31-6)17-2-1-7(19)16-15(17)25/h1-2,5-6,8-14,18,20-24H,3-4H2,(H,26,27)(H,28,29)(H,16,19,25)/t5-,6-,8-,9-,10+,11-,12+,13-,14-/m1/s1
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n/an/an/an/a 910n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y14 expressed in COS7 cells assessed as stimulation of PLC-mediated [3H]inositol hydrolsis


J Med Chem 50: 2030-9 (2007)


Article DOI: 10.1021/jm061222w
BindingDB Entry DOI: 10.7270/Q24Q7TPN
More data for this
Ligand-Target Pair
P2Y purinoceptor 14


(Homo sapiens (Human))
BDBM50209667
PNG
(CHEMBL387520 | diphosphoric acid 1-alpha-D-glucopy...)
Show SMILES O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)O[C@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)C(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=S
Show InChI InChI=1S/C15H22N2O17P2S/c18-5-1-2-17(15(37)16-5)12-9(22)6(19)4(31-12)3-30-35(26,27)34-36(28,29)33-14-10(23)7(20)8(21)11(32-14)13(24)25/h1-2,4,6-12,14,19-23H,3H2,(H,24,25)(H,26,27)(H,28,29)(H,16,18,37)/t4-,6-,7+,8+,9-,10-,11+,12-,14-/m1/s1
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n/an/an/an/a 420n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y14 expressed in COS7 cells assessed as stimulation of PLC-mediated [3H]inositol hydrolsis


J Med Chem 50: 2030-9 (2007)


Article DOI: 10.1021/jm061222w
BindingDB Entry DOI: 10.7270/Q24Q7TPN
More data for this
Ligand-Target Pair
P2Y purinoceptor 14


(Homo sapiens (Human))
BDBM50209669
PNG
(CHEMBL228111 | MRS-2670 | diphosphoric acid 1-alph...)
Show SMILES OC[C@H]1O[C@H](OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=S)[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C15H24N2O16P2S/c18-3-5-8(20)10(22)12(24)14(31-5)32-35(27,28)33-34(25,26)29-4-6-9(21)11(23)13(30-6)17-2-1-7(19)16-15(17)36/h1-2,5-6,8-14,18,20-24H,3-4H2,(H,25,26)(H,27,28)(H,16,19,36)/t5-,6-,8-,9-,10+,11-,12-,13-,14-/m1/s1
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n/an/an/an/a 49n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y14 expressed in COS7 cells assessed as stimulation of PLC-mediated [3H]inositol hydrolsis


J Med Chem 50: 2030-9 (2007)


Article DOI: 10.1021/jm061222w
BindingDB Entry DOI: 10.7270/Q24Q7TPN
More data for this
Ligand-Target Pair
P2Y purinoceptor 14


(Homo sapiens (Human))
BDBM50209668
PNG
(CHEMBL439009 | Galactose-Uridine-5'-Diphosphate)
Show SMILES OC[C@H]1O[C@H](OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)[C@H](O)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C15H24N2O17P2/c18-3-5-8(20)10(22)12(24)14(32-5)33-36(28,29)34-35(26,27)30-4-6-9(21)11(23)13(31-6)17-2-1-7(19)16-15(17)25/h1-2,5-6,8-14,18,20-24H,3-4H2,(H,26,27)(H,28,29)(H,16,19,25)/t5-,6-,8+,9-,10+,11-,12-,13-,14-/m1/s1
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n/an/an/an/a 670n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y14 expressed in COS7 cells assessed as stimulation of PLC-mediated [3H]inositol hydrolsis


J Med Chem 50: 2030-9 (2007)


Article DOI: 10.1021/jm061222w
BindingDB Entry DOI: 10.7270/Q24Q7TPN
More data for this
Ligand-Target Pair
P2Y purinoceptor 14


(Homo sapiens (Human))
BDBM50209659
PNG
(UDP-alpha-D-glucose | uridine 5'-[3-alpha-D-glucop...)
Show SMILES OC[C@H]1O[C@H](OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C15H24N2O17P2/c18-3-5-8(20)10(22)12(24)14(32-5)33-36(28,29)34-35(26,27)30-4-6-9(21)11(23)13(31-6)17-2-1-7(19)16-15(17)25/h1-2,5-6,8-14,18,20-24H,3-4H2,(H,26,27)(H,28,29)(H,16,19,25)/t5-,6-,8-,9-,10+,11-,12-,13-,14-/m1/s1
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n/an/an/an/a 261n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y14 receptor expressed in human COS7 cells


Bioorg Med Chem 17: 5298-311 (2009)


Article DOI: 10.1016/j.bmc.2009.05.024
BindingDB Entry DOI: 10.7270/Q28052Q7
More data for this
Ligand-Target Pair
P2Y purinoceptor 14


(Homo sapiens (Human))
BDBM50209669
PNG
(CHEMBL228111 | MRS-2670 | diphosphoric acid 1-alph...)
Show SMILES OC[C@H]1O[C@H](OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=S)[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C15H24N2O16P2S/c18-3-5-8(20)10(22)12(24)14(31-5)32-35(27,28)33-34(25,26)29-4-6-9(21)11(23)13(30-6)17-2-1-7(19)16-15(17)36/h1-2,5-6,8-14,18,20-24H,3-4H2,(H,25,26)(H,27,28)(H,16,19,36)/t5-,6-,8-,9-,10+,11-,12-,13-,14-/m1/s1
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n/an/an/an/a 49n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y14 receptor expressed in human COS7 cells


Bioorg Med Chem 17: 5298-311 (2009)


Article DOI: 10.1016/j.bmc.2009.05.024
BindingDB Entry DOI: 10.7270/Q28052Q7
More data for this
Ligand-Target Pair
P2Y purinoceptor 14


(Homo sapiens (Human))
BDBM50209663
PNG
(CHEMBL374384 | MRS-2670 | diphosphoric acid 1-alph...)
Show SMILES OC[C@H]1O[C@H](OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=S)[nH]c2=O)[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C15H24N2O16P2S/c18-3-5-8(19)10(21)12(23)14(31-5)32-35(27,28)33-34(25,26)29-4-6-9(20)11(22)13(30-6)17-2-1-7(36)16-15(17)24/h1-2,5-6,8-14,18-23H,3-4H2,(H,25,26)(H,27,28)(H,16,24,36)/t5-,6-,8-,9-,10+,11-,12-,13-,14-/m1/s1
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n/an/an/an/a 290n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y14 receptor expressed in human COS7 cells


Bioorg Med Chem 17: 5298-311 (2009)


Article DOI: 10.1016/j.bmc.2009.05.024
BindingDB Entry DOI: 10.7270/Q28052Q7
More data for this
Ligand-Target Pair
P2Y purinoceptor 14


(Homo sapiens (Human))
BDBM50304030
PNG
(CHEMBL595216 | Diphosphoric Acid 1''-beta-D-[1'']G...)
Show SMILES OC[C@H]1O[C@@H](OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)[C@H](O)[C@@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C15H24N2O17P2/c18-3-5-8(20)10(22)12(24)14(32-5)33-36(28,29)34-35(26,27)30-4-6-9(21)11(23)13(31-6)17-2-1-7(19)16-15(17)25/h1-2,5-6,8-14,18,20-24H,3-4H2,(H,26,27)(H,28,29)(H,16,19,25)/t5-,6-,8-,9-,10+,11-,12-,13-,14+/m1/s1
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n/an/an/an/a 588n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y14 receptor expressed in human COS7 cells


Bioorg Med Chem 17: 5298-311 (2009)


Article DOI: 10.1016/j.bmc.2009.05.024
BindingDB Entry DOI: 10.7270/Q28052Q7
More data for this
Ligand-Target Pair
P2Y purinoceptor 14


(Homo sapiens (Human))
BDBM50209666
PNG
(CHEMBL227711 | URIDINE-5'-DIPHOSPHATE-MANNOSE)
Show SMILES OC[C@H]1O[C@H](OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)[C@@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C15H24N2O17P2/c18-3-5-8(20)10(22)12(24)14(32-5)33-36(28,29)34-35(26,27)30-4-6-9(21)11(23)13(31-6)17-2-1-7(19)16-15(17)25/h1-2,5-6,8-14,18,20-24H,3-4H2,(H,26,27)(H,28,29)(H,16,19,25)/t5-,6-,8-,9-,10+,11-,12+,13-,14-/m1/s1
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n/an/an/an/a 910n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y14 receptor expressed in human COS7 cells


Bioorg Med Chem 17: 5298-311 (2009)


Article DOI: 10.1016/j.bmc.2009.05.024
BindingDB Entry DOI: 10.7270/Q28052Q7
More data for this
Ligand-Target Pair
P2Y purinoceptor 14


(Homo sapiens (Human))
BDBM50209668
PNG
(CHEMBL439009 | Galactose-Uridine-5'-Diphosphate)
Show SMILES OC[C@H]1O[C@H](OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)[C@H](O)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C15H24N2O17P2/c18-3-5-8(20)10(22)12(24)14(32-5)33-36(28,29)34-35(26,27)30-4-6-9(21)11(23)13(31-6)17-2-1-7(19)16-15(17)25/h1-2,5-6,8-14,18,20-24H,3-4H2,(H,26,27)(H,28,29)(H,16,19,25)/t5-,6-,8+,9-,10+,11-,12-,13-,14-/m1/s1
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n/an/an/an/a 670n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y14 receptor expressed in human COS7 cells


Bioorg Med Chem 17: 5298-311 (2009)


Article DOI: 10.1016/j.bmc.2009.05.024
BindingDB Entry DOI: 10.7270/Q28052Q7
More data for this
Ligand-Target Pair
P2Y purinoceptor 14


(Homo sapiens (Human))
BDBM50304031
PNG
(CHEMBL595940 | Diphosphoric Acid 1''-alpha-D-[1'']...)
Show SMILES C[C@H]1O[C@H](OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)[C@H](O)[C@@H](O)[C@H]1O |r|
Show InChI InChI=1S/C15H24N2O16P2/c1-5-8(19)10(21)12(23)14(30-5)32-35(27,28)33-34(25,26)29-4-6-9(20)11(22)13(31-6)17-3-2-7(18)16-15(17)24/h2-3,5-6,8-14,19-23H,4H2,1H3,(H,25,26)(H,27,28)(H,16,18,24)/t5-,6-,8+,9-,10+,11-,12-,13-,14-/m1/s1
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n/an/an/an/a 562n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y14 receptor expressed in human COS7 cells


Bioorg Med Chem 17: 5298-311 (2009)


Article DOI: 10.1016/j.bmc.2009.05.024
BindingDB Entry DOI: 10.7270/Q28052Q7
More data for this
Ligand-Target Pair
P2Y purinoceptor 14


(Homo sapiens (Human))
BDBM50304032
PNG
(CHEMBL593830 | Diphosphoric Acid 1''-alpha-D-[1'']...)
Show SMILES OC[C@H]1O[C@H](OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)[C@H](F)[C@@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C15H23FN2O16P2/c16-8-11(23)9(21)5(3-19)32-14(8)33-36(28,29)34-35(26,27)30-4-6-10(22)12(24)13(31-6)18-2-1-7(20)17-15(18)25/h1-2,5-6,8-14,19,21-24H,3-4H2,(H,26,27)(H,28,29)(H,17,20,25)/t5-,6-,8-,9-,10-,11-,12-,13-,14-/m1/s1
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n/an/an/an/a 2.50E+3n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y14 receptor expressed in human COS7 cells


Bioorg Med Chem 17: 5298-311 (2009)


Article DOI: 10.1016/j.bmc.2009.05.024
BindingDB Entry DOI: 10.7270/Q28052Q7
More data for this
Ligand-Target Pair
P2Y purinoceptor 14


(Homo sapiens (Human))
BDBM50304033
PNG
(CHEMBL594064 | Diphosphoric Acid 1''-alpha-D-[1'']...)
Show SMILES OC[C@H]1O[C@H](OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)[C@H](O)[C@@H](F)[C@@H]1O |r|
Show InChI InChI=1S/C15H23FN2O16P2/c16-8-9(21)5(3-19)32-14(11(8)23)33-36(28,29)34-35(26,27)30-4-6-10(22)12(24)13(31-6)18-2-1-7(20)17-15(18)25/h1-2,5-6,8-14,19,21-24H,3-4H2,(H,26,27)(H,28,29)(H,17,20,25)/t5-,6-,8+,9-,10-,11-,12-,13-,14-/m1/s1
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n/an/an/an/a 361n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y14 receptor expressed in human COS7 cells


Bioorg Med Chem 17: 5298-311 (2009)


Article DOI: 10.1016/j.bmc.2009.05.024
BindingDB Entry DOI: 10.7270/Q28052Q7
More data for this
Ligand-Target Pair
P2Y purinoceptor 14


(Homo sapiens (Human))
BDBM50304034
PNG
(CHEMBL593125 | Diphosphoric Acid 1''-alpha-D-[1'']...)
Show SMILES OC[C@H]1O[C@H](OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)[C@H](O)[C@@H](O)[C@@H]1F |r|
Show InChI InChI=1S/C15H23FN2O16P2/c16-8-5(3-19)32-14(12(24)10(8)22)33-36(28,29)34-35(26,27)30-4-6-9(21)11(23)13(31-6)18-2-1-7(20)17-15(18)25/h1-2,5-6,8-14,19,21-24H,3-4H2,(H,26,27)(H,28,29)(H,17,20,25)/t5-,6-,8-,9-,10+,11-,12-,13-,14-/m1/s1
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n/an/an/an/a 567n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y14 receptor expressed in human COS7 cells


Bioorg Med Chem 17: 5298-311 (2009)


Article DOI: 10.1016/j.bmc.2009.05.024
BindingDB Entry DOI: 10.7270/Q28052Q7
More data for this
Ligand-Target Pair
P2Y purinoceptor 14


(Homo sapiens (Human))
BDBM50304035
PNG
(CHEMBL593126 | Diphosphoric Acid 1''-alpha-D-[1'']...)
Show SMILES O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)O[C@H]2O[C@H](CF)[C@@H](O)[C@H](O)[C@H]2O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O |r|
Show InChI InChI=1S/C15H23FN2O16P2/c16-3-5-8(20)10(22)12(24)14(32-5)33-36(28,29)34-35(26,27)30-4-6-9(21)11(23)13(31-6)18-2-1-7(19)17-15(18)25/h1-2,5-6,8-14,20-24H,3-4H2,(H,26,27)(H,28,29)(H,17,19,25)/t5-,6-,8-,9-,10+,11-,12-,13-,14-/m1/s1
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n/an/an/an/a 905n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y14 receptor expressed in human COS7 cells


Bioorg Med Chem 17: 5298-311 (2009)


Article DOI: 10.1016/j.bmc.2009.05.024
BindingDB Entry DOI: 10.7270/Q28052Q7
More data for this
Ligand-Target Pair
P2Y purinoceptor 14


(Homo sapiens (Human))
BDBM50209665
PNG
(CHEMBL228057 | UDP-alpha-D-glucuronic acid | uridi...)
Show SMILES O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)O[C@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)C(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O
Show InChI InChI=1S/C15H22N2O18P2/c18-5-1-2-17(15(26)16-5)12-9(22)6(19)4(32-12)3-31-36(27,28)35-37(29,30)34-14-10(23)7(20)8(21)11(33-14)13(24)25/h1-2,4,6-12,14,19-23H,3H2,(H,24,25)(H,27,28)(H,29,30)(H,16,18,26)/t4-,6-,7+,8+,9-,10-,11+,12-,14-/m1/s1
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n/an/an/an/a 370n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y14 receptor expressed in human COS7 cells


Bioorg Med Chem 17: 5298-311 (2009)


Article DOI: 10.1016/j.bmc.2009.05.024
BindingDB Entry DOI: 10.7270/Q28052Q7
More data for this
Ligand-Target Pair
P2Y purinoceptor 14


(Homo sapiens (Human))
BDBM50304036
PNG
(CHEMBL605512 | Diphosphoric acid 1''-alpha-D-[1'']...)
Show SMILES NCCNC(=O)[C@H]1O[C@H](OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)[C@H](O)[C@@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C17H28N4O17P2/c18-2-3-19-14(28)13-10(25)9(24)12(27)16(36-13)37-40(32,33)38-39(30,31)34-5-6-8(23)11(26)15(35-6)21-4-1-7(22)20-17(21)29/h1,4,6,8-13,15-16,23-27H,2-3,5,18H2,(H,19,28)(H,30,31)(H,32,33)(H,20,22,29)/t6-,8-,9+,10+,11-,12-,13+,15-,16-/m1/s1
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n/an/an/an/a 2.59E+3n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y14 receptor expressed in human COS7 cells


Bioorg Med Chem 17: 5298-311 (2009)


Article DOI: 10.1016/j.bmc.2009.05.024
BindingDB Entry DOI: 10.7270/Q28052Q7
More data for this
Ligand-Target Pair
P2Y purinoceptor 14


(Homo sapiens (Human))
BDBM50304037
PNG
(CHEMBL595076 | {[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,...)
Show SMILES CC(=O)NCCNC(=O)[C@H]1O[C@H](OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)[C@H](O)[C@@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C19H30N4O18P2/c1-7(24)20-3-4-21-16(31)15-12(28)11(27)14(30)18(39-15)40-43(35,36)41-42(33,34)37-6-8-10(26)13(29)17(38-8)23-5-2-9(25)22-19(23)32/h2,5,8,10-15,17-18,26-30H,3-4,6H2,1H3,(H,20,24)(H,21,31)(H,33,34)(H,35,36)(H,22,25,32)/t8-,10-,11+,12+,13-,14-,15+,17-,18-/m1/s1
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n/an/an/an/a 496n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y14 receptor expressed in human COS7 cells


Bioorg Med Chem 17: 5298-311 (2009)


Article DOI: 10.1016/j.bmc.2009.05.024
BindingDB Entry DOI: 10.7270/Q28052Q7
More data for this
Ligand-Target Pair
P2Y purinoceptor 14


(Homo sapiens (Human))
BDBM50304038
PNG
(CHEMBL594065 | Diphosphoric Acid 1''-alpha-D-[6'']...)
Show SMILES O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H](O)[C@H](O)[C@@H](O)[C@@H]2O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O |r|
Show InChI InChI=1S/C15H24N2O17P2/c18-7-1-2-17(15(25)16-7)13-11(22)9(20)5(32-13)3-30-35(26,27)34-36(28,29)31-4-6-8(19)10(21)12(23)14(24)33-6/h1-2,5-6,8-14,19-24H,3-4H2,(H,26,27)(H,28,29)(H,16,18,25)/t5-,6-,8-,9-,10+,11-,12-,13-,14+/m1/s1
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n/an/an/an/a 373n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y14 receptor expressed in human COS7 cells


Bioorg Med Chem 17: 5298-311 (2009)


Article DOI: 10.1016/j.bmc.2009.05.024
BindingDB Entry DOI: 10.7270/Q28052Q7
More data for this
Ligand-Target Pair
P2Y purinoceptor 14


(Homo sapiens (Human))
BDBM50304039
PNG
(CHEMBL596145 | Diphosphoric Acid 1''-alpha-D-[6'']...)
Show SMILES O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H](O)[C@@H](O)[C@@H](O)[C@@H]2O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O |r|
Show InChI InChI=1S/C15H24N2O17P2/c18-7-1-2-17(15(25)16-7)13-11(22)9(20)5(32-13)3-30-35(26,27)34-36(28,29)31-4-6-8(19)10(21)12(23)14(24)33-6/h1-2,5-6,8-14,19-24H,3-4H2,(H,26,27)(H,28,29)(H,16,18,25)/t5-,6-,8-,9-,10+,11-,12+,13-,14+/m1/s1
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n/an/an/an/a 658n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y14 receptor expressed in human COS7 cells


Bioorg Med Chem 17: 5298-311 (2009)


Article DOI: 10.1016/j.bmc.2009.05.024
BindingDB Entry DOI: 10.7270/Q28052Q7
More data for this
Ligand-Target Pair
P2Y purinoceptor 14


(Homo sapiens (Human))
BDBM50304040
PNG
(CHEMBL595467 | Diphosphoric Acid 1''-alpha-D-[5'']...)
Show SMILES O[C@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)[C@@H](O)[C@H]1O |r|
Show InChI InChI=1S/C14H22N2O16P2/c17-7-1-2-16(14(23)15-7)12-10(20)8(18)5(30-12)3-28-33(24,25)32-34(26,27)29-4-6-9(19)11(21)13(22)31-6/h1-2,5-6,8-13,18-22H,3-4H2,(H,24,25)(H,26,27)(H,15,17,23)/t5-,6-,8-,9-,10-,11-,12-,13+/m1/s1
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n/an/an/an/a 238n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y14 receptor expressed in human COS7 cells


Bioorg Med Chem 17: 5298-311 (2009)


Article DOI: 10.1016/j.bmc.2009.05.024
BindingDB Entry DOI: 10.7270/Q28052Q7
More data for this
Ligand-Target Pair
P2Y purinoceptor 14


(Homo sapiens (Human))
BDBM50304041
PNG
(CHEMBL593842 | Diphosphoric Acid 1''-alpha-D-[5'']...)
Show SMILES O[C@H]1O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)[C@@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C14H22N2O16P2/c17-7-1-2-16(14(23)15-7)12-10(20)8(18)5(30-12)3-28-33(24,25)32-34(26,27)29-4-6-9(19)11(21)13(22)31-6/h1-2,5-6,8-13,18-22H,3-4H2,(H,24,25)(H,26,27)(H,15,17,23)/t5-,6-,8-,9-,10-,11+,12-,13+/m1/s1
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n/an/an/an/a 460n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y14 receptor expressed in human COS7 cells


Bioorg Med Chem 17: 5298-311 (2009)


Article DOI: 10.1016/j.bmc.2009.05.024
BindingDB Entry DOI: 10.7270/Q28052Q7
More data for this
Ligand-Target Pair
P2Y purinoceptor 14


(Homo sapiens (Human))
BDBM50209661
PNG
(CHEMBL226713 | [({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,...)
Show SMILES OC[C@H]1O[C@](O)(COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C15H24N2O17P2/c18-3-6-10(21)12(23)15(25,33-6)5-31-36(28,29)34-35(26,27)30-4-7-9(20)11(22)13(32-7)17-2-1-8(19)16-14(17)24/h1-2,6-7,9-13,18,20-23,25H,3-5H2,(H,26,27)(H,28,29)(H,16,19,24)/t6-,7-,9-,10-,11-,12+,13-,15-/m1/s1
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n/an/an/an/a 880n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y14 receptor expressed in human COS7 cells


Bioorg Med Chem 17: 5298-311 (2009)


Article DOI: 10.1016/j.bmc.2009.05.024
BindingDB Entry DOI: 10.7270/Q28052Q7
More data for this
Ligand-Target Pair
P2Y purinoceptor 14


(Homo sapiens (Human))
BDBM50304042
PNG
(CHEMBL604676 | Diphosphoric Acid 1''-alpha-D-[1'']...)
Show SMILES OC[C@@]1(O)O[C@H](COP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)[C@@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C15H24N2O17P2/c18-5-15(25)12(23)10(21)7(33-15)4-31-36(28,29)34-35(26,27)30-3-6-9(20)11(22)13(32-6)17-2-1-8(19)16-14(17)24/h1-2,6-7,9-13,18,20-23,25H,3-5H2,(H,26,27)(H,28,29)(H,16,19,24)/t6-,7-,9-,10-,11-,12+,13-,15-/m1/s1
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n/an/an/an/a 323n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y14 receptor expressed in human COS7 cells


Bioorg Med Chem 17: 5298-311 (2009)


Article DOI: 10.1016/j.bmc.2009.05.024
BindingDB Entry DOI: 10.7270/Q28052Q7
More data for this
Ligand-Target Pair
P2Y purinoceptor 14


(Homo sapiens (Human))
BDBM50304043
PNG
(CHEMBL593346 | {[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,...)
Show SMILES O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)O[C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]2O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O |r|
Show InChI InChI=1S/C15H24N2O17P2/c18-5-1-2-17(15(26)16-5)14-12(25)6(19)4(32-14)3-31-35(27,28)34-36(29,30)33-13-10(23)8(21)7(20)9(22)11(13)24/h1-2,4,6-14,19-25H,3H2,(H,27,28)(H,29,30)(H,16,18,26)/t4-,6-,7-,8-,9+,10-,11-,12-,13-,14-/m1/s1
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n/an/an/an/a 1.88E+3n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y14 receptor expressed in human COS7 cells


Bioorg Med Chem 17: 5298-311 (2009)


Article DOI: 10.1016/j.bmc.2009.05.024
BindingDB Entry DOI: 10.7270/Q28052Q7
More data for this
Ligand-Target Pair
P2Y purinoceptor 14


(Homo sapiens (Human))
BDBM50304044
PNG
(CHEMBL594703 | [({[(2R,3R,4S,5S,6S)-6-[(2-{[(tert-...)
Show SMILES CC(C)(C)OC(=O)NCCNC(=O)[C@H]1O[C@H](OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)[C@H](O)[C@@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C22H36N4O19P2/c1-22(2,3)43-21(35)24-6-5-23-17(33)16-13(30)12(29)15(32)19(42-16)44-47(38,39)45-46(36,37)40-8-9-11(28)14(31)18(41-9)26-7-4-10(27)25-20(26)34/h4,7,9,11-16,18-19,28-32H,5-6,8H2,1-3H3,(H,23,33)(H,24,35)(H,36,37)(H,38,39)(H,25,27,34)/t9-,11-,12+,13+,14-,15-,16+,18-,19-/m1/s1
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n/an/an/an/a 951n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y14 receptor expressed in human COS7 cells


Bioorg Med Chem 17: 5298-311 (2009)


Article DOI: 10.1016/j.bmc.2009.05.024
BindingDB Entry DOI: 10.7270/Q28052Q7
More data for this
Ligand-Target Pair
P2Y purinoceptor 14


(Homo sapiens (Human))
BDBM50197974
PNG
(udp-N-acetyl-glucosamine)
Show SMILES CC(=O)N[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1OP([O-])(=O)OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O
Show InChI InChI=1S/C17H27N3O17P2/c1-6(22)18-10-13(26)11(24)7(4-21)35-16(10)36-39(31,32)37-38(29,30)33-5-8-12(25)14(27)15(34-8)20-3-2-9(23)19-17(20)28/h2-3,7-8,10-16,21,24-27H,4-5H2,1H3,(H,18,22)(H,29,30)(H,31,32)(H,19,23,28)/p-2/t7-,8+,10-,11-,12+,13-,14+,15+,16-/m0/s1
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n/an/an/an/a 4.38E+3n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y14 receptor expressed in COS7 cells assessed as stimulation of PLC


Bioorg Med Chem Lett 17: 761-6 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.081
BindingDB Entry DOI: 10.7270/Q2KW5GW6
More data for this
Ligand-Target Pair
P2Y purinoceptor 14


(Homo sapiens (Human))
BDBM50197975
PNG
(udp-glucuronic acid)
Show SMILES O[C@@H]1[C@@H](COP([O-])(=O)OP([O-])(=O)O[C@@H]2O[C@H]([C@H](O)[C@@H](O)[C@@H]2O)C(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O
Show InChI InChI=1S/C15H22N2O18P2/c18-5-1-2-17(15(26)16-5)12-9(22)6(19)4(32-12)3-31-36(27,28)35-37(29,30)34-14-10(23)7(20)8(21)11(33-14)13(24)25/h1-2,4,6-12,14,19-23H,3H2,(H,24,25)(H,27,28)(H,29,30)(H,16,18,26)/p-2/t4-,6-,7-,8-,9-,10+,11-,12-,14+/m1/s1
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n/an/an/an/a 370n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y14 receptor expressed in COS7 cells assessed as stimulation of PLC


Bioorg Med Chem Lett 17: 761-6 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.081
BindingDB Entry DOI: 10.7270/Q2KW5GW6
More data for this
Ligand-Target Pair
P2Y purinoceptor 14


(Homo sapiens (Human))
BDBM50370674
PNG
(UDP-GALACTOSE)
Show SMILES OC[C@H]1O[C@H](OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)c2cc(=O)[nH]c(=O)[nH]2)[C@H](O)[C@@H](O)[C@H]1O |r|
Show InChI InChI=1S/C15H24N2O17P2/c18-2-5-8(20)10(22)12(24)14(32-5)33-36(28,29)34-35(26,27)30-3-6-9(21)11(23)13(31-6)4-1-7(19)17-15(25)16-4/h1,5-6,8-14,18,20-24H,2-3H2,(H,26,27)(H,28,29)(H2,16,17,19,25)/t5-,6-,8+,9-,10+,11-,12-,13+,14-/m1/s1
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n/an/an/an/a 671n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human P2Y14 receptor expressed in COS7 cells assessed as stimulation of PLC


Bioorg Med Chem Lett 17: 761-6 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.081
BindingDB Entry DOI: 10.7270/Q2KW5GW6
More data for this
Ligand-Target Pair
P2Y purinoceptor 2


(Homo sapiens (Human))
BDBM50366480
PNG
(ADENOSINE TRIPHOSPHATE | ATP)
Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O |r|
Show InChI InChI=1S/C10H16N5O13P3/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1
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n/an/an/an/a 85n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant P2Y2 receptor expressed in 1321N1 cells assessed as stimulation of phospholipase C


J Med Chem 50: 1166-76 (2007)


Article DOI: 10.1021/jm060903o
BindingDB Entry DOI: 10.7270/Q2PK0GZ1
More data for this
Ligand-Target Pair
P2Y purinoceptor 2


(Homo sapiens (Human))
BDBM50199176
PNG
(2-thio-1-beta-D-ribofuranosyl(3H)pyrimidine-2,4-di...)
Show SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)n1ccc(=O)[nH]c1=S |r|
Show InChI InChI=1S/C9H15N2O14P3S/c12-5-1-2-11(9(29)10-5)8-7(14)6(13)4(23-8)3-22-27(18,19)25-28(20,21)24-26(15,16)17/h1-2,4,6-8,13-14H,3H2,(H,18,19)(H,20,21)(H,10,12,29)(H2,15,16,17)/t4-,6-,7-,8-/m1/s1
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n/an/an/an/a 35n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant P2Y2 receptor expressed in 1321N1 cells assessed as stimulation of phospholipase C


J Med Chem 50: 1166-76 (2007)


Article DOI: 10.1021/jm060903o
BindingDB Entry DOI: 10.7270/Q2PK0GZ1
More data for this
Ligand-Target Pair
P2Y purinoceptor 4


(Homo sapiens (Human))
BDBM50205408
PNG
(2'-trifluoroacetylamino-2'-deoxy-2-thiouridine 5'-...)
Show SMILES CC(C)(C)C(=O)N[C@@H]1[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]1n1ccc(=O)[nH]c1=S
Show InChI InChI=1S/C14H24N3O14P3S/c1-14(2,3)12(20)16-9-10(19)7(29-11(9)17-5-4-8(18)15-13(17)35)6-28-33(24,25)31-34(26,27)30-32(21,22)23/h4-5,7,9-11,19H,6H2,1-3H3,(H,16,20)(H,24,25)(H,26,27)(H,15,18,35)(H2,21,22,23)/t7-,9-,10-,11-/m1/s1
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n/an/an/an/a 8.30E+3n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant P2Y4 receptor expressed in 1321N1 cells assessed as stimulation of phospholipase C


J Med Chem 50: 1166-76 (2007)


Article DOI: 10.1021/jm060903o
BindingDB Entry DOI: 10.7270/Q2PK0GZ1
More data for this
Ligand-Target Pair
P2Y purinoceptor 2


(Homo sapiens (Human))
BDBM50205409
PNG
(({[({[(2R,3S,4R,5R)-5-(5-amino-2,4-dioxo-1,2,3,4-t...)
Show SMILES Nc1cn([C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c(=O)[nH]c1=O
Show InChI InChI=1S/C9H16N3O15P3/c10-3-1-12(9(16)11-7(3)15)8-6(14)5(13)4(25-8)2-24-29(20,21)27-30(22,23)26-28(17,18)19/h1,4-6,8,13-14H,2,10H2,(H,20,21)(H,22,23)(H,11,15,16)(H2,17,18,19)/t4-,5-,6-,8-/m1/s1
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n/an/an/an/a 5.60E+3n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant P2Y2 receptor expressed in 1321N1 cells assessed as stimulation of phospholipase C


J Med Chem 50: 1166-76 (2007)


Article DOI: 10.1021/jm060903o
BindingDB Entry DOI: 10.7270/Q2PK0GZ1
More data for this
Ligand-Target Pair
P2Y purinoceptor 4


(Homo sapiens (Human))
BDBM50205405
PNG
(({[({[(2R,3S,4R,5R)-4-amino-5-(2,4-dioxo-1,2,3,4-t...)
Show SMILES N[C@@H]1[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]1n1ccc(=O)[nH]c1=O |r|
Show InChI InChI=1S/C9H16N3O14P3/c10-6-7(14)4(24-8(6)12-2-1-5(13)11-9(12)15)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,14H,3,10H2,(H,19,20)(H,21,22)(H,11,13,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1
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n/an/an/an/a 1.20E+3n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant P2Y4 receptor expressed in 1321N1 cells assessed as stimulation of phospholipase C


J Med Chem 50: 1166-76 (2007)


Article DOI: 10.1021/jm060903o
BindingDB Entry DOI: 10.7270/Q2PK0GZ1
More data for this
Ligand-Target Pair
P2Y purinoceptor 6


(Homo sapiens (Human))
BDBM50205406
PNG
(((2R,3S,4R,5R)-4-amino-3-hydroxy-5-(4-oxo-2-thioxo...)
Show SMILES N[C@@H]1[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]1n1ccc(=O)[nH]c1=S |r|
Show InChI InChI=1S/C9H16N3O13P3S/c10-6-7(14)4(23-8(6)12-2-1-5(13)11-9(12)29)3-22-27(18,19)25-28(20,21)24-26(15,16)17/h1-2,4,6-8,14H,3,10H2,(H,18,19)(H,20,21)(H,11,13,29)(H2,15,16,17)/t4-,6-,7-,8-/m1/s1
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n/an/an/an/a>1.00E+4n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as stimulation of phospholipase C


J Med Chem 50: 1166-76 (2007)


Article DOI: 10.1021/jm060903o
BindingDB Entry DOI: 10.7270/Q2PK0GZ1
More data for this
Ligand-Target Pair
P2Y purinoceptor 6


(Homo sapiens (Human))
BDBM50205407
PNG
(({[({[(2R,3S,4R,5R)-5-(5-azido-2,4-dioxo-1,2,3,4-t...)
Show SMILES O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1cc(N=[N+]=[N-])c(=O)[nH]c1=O
Show InChI InChI=1S/C9H14N5O15P3/c10-13-12-3-1-14(9(18)11-7(3)17)8-6(16)5(15)4(27-8)2-26-31(22,23)29-32(24,25)28-30(19,20)21/h1,4-6,8,15-16H,2H2,(H,22,23)(H,24,25)(H,11,17,18)(H2,19,20,21)/t4-,5-,6-,8-/m1/s1
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n/an/an/an/a 467n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as stimulation of phospholipase C


J Med Chem 50: 1166-76 (2007)


Article DOI: 10.1021/jm060903o
BindingDB Entry DOI: 10.7270/Q2PK0GZ1
More data for this
Ligand-Target Pair
P2Y purinoceptor 2


(Homo sapiens (Human))
BDBM50270553
PNG
(CHEMBL507282 | INS-37217 | INS37217)
Show SMILES Nc1ccn([C@H]2C[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]3O[C@H]([C@H](O)[C@@H]3O)n3ccc(=O)[nH]c3=O)O2)c(=O)n1 |r|
Show InChI InChI=1S/C18H27N5O21P4/c19-11-1-3-22(17(28)20-11)13-5-8(24)9(40-13)6-38-45(30,31)42-47(34,35)44-48(36,37)43-46(32,33)39-7-10-14(26)15(27)16(41-10)23-4-2-12(25)21-18(23)29/h1-4,8-10,13-16,24,26-27H,5-7H2,(H,30,31)(H,32,33)(H,34,35)(H,36,37)(H2,19,20,28)(H,21,25,29)/t8-,9+,10+,13+,14+,15+,16+/m0/s1
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n/an/an/an/a 270n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant P2Y2 receptor expressed in 1321N1 cells assessed as stimulation of phospholipase C


J Med Chem 50: 1166-76 (2007)


Article DOI: 10.1021/jm060903o
BindingDB Entry DOI: 10.7270/Q2PK0GZ1
More data for this
Ligand-Target Pair
P2Y purinoceptor 6


(Homo sapiens (Human))
BDBM50205405
PNG
(({[({[(2R,3S,4R,5R)-4-amino-5-(2,4-dioxo-1,2,3,4-t...)
Show SMILES N[C@@H]1[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]1n1ccc(=O)[nH]c1=O |r|
Show InChI InChI=1S/C9H16N3O14P3/c10-6-7(14)4(24-8(6)12-2-1-5(13)11-9(12)15)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,14H,3,10H2,(H,19,20)(H,21,22)(H,11,13,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1
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n/an/an/an/a>1.00E+5n/an/an/an/a



National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as stimulation of phospholipase C


J Med Chem 50: 1166-76 (2007)


Article DOI: 10.1021/jm060903o
BindingDB Entry DOI: 10.7270/Q2PK0GZ1
More data for this
Ligand-Target Pair
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