Compile Data Set for Download or QSAR

Found 32 hits with Last Name = 'fritsche' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Survival motor neuron protein (Homo sapiens)	BDBM50242551 (CHEMBL4081345) Show SMILES CC(C)c1cc(no1)C(=O)N1CCc2ccccc12 Show InChI InChI=1S/C15H16N2O2/c1-10(2)14-9-12(16-19-14)15(18)17-8-7-11-5-3-4-6-13(11)17/h3-6,9-10H,7-8H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	720	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Stabilization of human SMN protein expressed in HEK293 cells expressing SMN2 promoter after 24 hrs by luciferase reporter gene assay				J Med Chem 60: 4594-4610 (2017) Article DOI: 10.1021/acs.jmedchem.6b01885 BindingDB Entry DOI: 10.7270/Q2DF6TM3
					More data for this Ligand-Target Pair
Survival motor neuron protein (Homo sapiens)	BDBM50242607 (CHEMBL4084011) Show SMILES CC(C)c1cc(no1)C(=O)Nc1ccc(F)cc1 Show InChI InChI=1S/C13H13FN2O2/c1-8(2)12-7-11(16-18-12)13(17)15-10-5-3-9(14)4-6-10/h3-8H,1-2H3,(H,15,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Stabilization of human SMN protein expressed in HEK293 cells expressing SMN2 promoter after 24 hrs by luciferase reporter gene assay				J Med Chem 60: 4594-4610 (2017) Article DOI: 10.1021/acs.jmedchem.6b01885 BindingDB Entry DOI: 10.7270/Q2DF6TM3
					More data for this Ligand-Target Pair
Survival motor neuron protein (Homo sapiens)	BDBM50242553 (CHEMBL4074761) Show SMILES Fc1ccc(NC(=O)c2cc(Cc3ccccc3)on2)cc1Cl Show InChI InChI=1S/C17H12ClFN2O2/c18-14-9-12(6-7-15(14)19)20-17(22)16-10-13(23-21-16)8-11-4-2-1-3-5-11/h1-7,9-10H,8H2,(H,20,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.56E+3	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Stabilization of human SMN protein expressed in HEK293 cells expressing SMN2 promoter after 24 hrs by luciferase reporter gene assay				J Med Chem 60: 4594-4610 (2017) Article DOI: 10.1021/acs.jmedchem.6b01885 BindingDB Entry DOI: 10.7270/Q2DF6TM3
					More data for this Ligand-Target Pair
Survival motor neuron protein (Homo sapiens)	BDBM50242554 (CHEMBL4092778) Show SMILES CC(C)(C)c1cc(no1)C(=O)Nc1ccc(F)c(Cl)c1 Show InChI InChI=1S/C14H14ClFN2O2/c1-14(2,3)12-7-11(18-20-12)13(19)17-8-4-5-10(16)9(15)6-8/h4-7H,1-3H3,(H,17,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.93E+3	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Stabilization of human SMN protein expressed in HEK293 cells expressing SMN2 promoter after 24 hrs by luciferase reporter gene assay				J Med Chem 60: 4594-4610 (2017) Article DOI: 10.1021/acs.jmedchem.6b01885 BindingDB Entry DOI: 10.7270/Q2DF6TM3
					More data for this Ligand-Target Pair
Survival motor neuron protein (Homo sapiens)	BDBM50242555 (CHEMBL4100508) Show SMILES CCc1cc(no1)C(=O)Nc1ccc(F)c(Cl)c1 Show InChI InChI=1S/C12H10ClFN2O2/c1-2-8-6-11(16-18-8)12(17)15-7-3-4-10(14)9(13)5-7/h3-6H,2H2,1H3,(H,15,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Stabilization of human SMN protein expressed in HEK293 cells expressing SMN2 promoter after 24 hrs by luciferase reporter gene assay				J Med Chem 60: 4594-4610 (2017) Article DOI: 10.1021/acs.jmedchem.6b01885 BindingDB Entry DOI: 10.7270/Q2DF6TM3
					More data for this Ligand-Target Pair
Survival motor neuron protein (Homo sapiens)	BDBM50242559 (CHEMBL4091509) Show SMILES CC(C)c1cc(no1)C(=O)Nc1nc2ccccc2s1 Show InChI InChI=1S/C14H13N3O2S/c1-8(2)11-7-10(17-19-11)13(18)16-14-15-9-5-3-4-6-12(9)20-14/h3-8H,1-2H3,(H,15,16,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	170	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Stabilization of human SMN protein expressed in HEK293 cells expressing SMN2 promoter after 24 hrs by luciferase reporter gene assay				J Med Chem 60: 4594-4610 (2017) Article DOI: 10.1021/acs.jmedchem.6b01885 BindingDB Entry DOI: 10.7270/Q2DF6TM3
					More data for this Ligand-Target Pair
Survival motor neuron protein (Homo sapiens)	BDBM50242560 (CHEMBL4081226) Show SMILES CC(C)c1cc(no1)C(=O)Nc1nc2ccccc2n1C Show InChI InChI=1S/C15H16N4O2/c1-9(2)13-8-11(18-21-13)14(20)17-15-16-10-6-4-5-7-12(10)19(15)3/h4-9H,1-3H3,(H,16,17,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Stabilization of human SMN protein expressed in HEK293 cells expressing SMN2 promoter after 24 hrs by luciferase reporter gene assay				J Med Chem 60: 4594-4610 (2017) Article DOI: 10.1021/acs.jmedchem.6b01885 BindingDB Entry DOI: 10.7270/Q2DF6TM3
					More data for this Ligand-Target Pair
Survival motor neuron protein (Homo sapiens)	BDBM50242561 (CHEMBL4060907) Show SMILES CC(C)c1cc(no1)C(=O)Nc1nccs1 Show InChI InChI=1S/C10H11N3O2S/c1-6(2)8-5-7(13-15-8)9(14)12-10-11-3-4-16-10/h3-6H,1-2H3,(H,11,12,14)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	780	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Stabilization of human SMN protein expressed in HEK293 cells expressing SMN2 promoter after 24 hrs by luciferase reporter gene assay				J Med Chem 60: 4594-4610 (2017) Article DOI: 10.1021/acs.jmedchem.6b01885 BindingDB Entry DOI: 10.7270/Q2DF6TM3
					More data for this Ligand-Target Pair
Survival motor neuron protein (Homo sapiens)	BDBM56067 (5-isopropyl-N-(3-pyridyl)isoxazole-3-carboxamide |...) Show SMILES CC(C)c1cc(no1)C(=O)Nc1cccnc1 Show InChI InChI=1S/C12H13N3O2/c1-8(2)11-6-10(15-17-11)12(16)14-9-4-3-5-13-7-9/h3-8H,1-2H3,(H,14,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9.90E+3	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Stabilization of human SMN protein expressed in HEK293 cells expressing SMN2 promoter after 24 hrs by luciferase reporter gene assay				J Med Chem 60: 4594-4610 (2017) Article DOI: 10.1021/acs.jmedchem.6b01885 BindingDB Entry DOI: 10.7270/Q2DF6TM3
					More data for this Ligand-Target Pair
Survival motor neuron protein (Homo sapiens)	BDBM50242562 (CHEMBL4085268) Show SMILES CC(C)c1cc(no1)C(=O)Nc1ccccn1 Show InChI InChI=1S/C12H13N3O2/c1-8(2)10-7-9(15-17-10)12(16)14-11-5-3-4-6-13-11/h3-8H,1-2H3,(H,13,14,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	360	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Stabilization of human SMN protein expressed in HEK293 cells expressing SMN2 promoter after 24 hrs by luciferase reporter gene assay				J Med Chem 60: 4594-4610 (2017) Article DOI: 10.1021/acs.jmedchem.6b01885 BindingDB Entry DOI: 10.7270/Q2DF6TM3
					More data for this Ligand-Target Pair
Survival motor neuron protein (Homo sapiens)	BDBM50242563 (CHEMBL4097356) Show SMILES CC(C)c1cc(no1)C(=O)Nc1cccc(C)c1 Show InChI InChI=1S/C14H16N2O2/c1-9(2)13-8-12(16-18-13)14(17)15-11-6-4-5-10(3)7-11/h4-9H,1-3H3,(H,15,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Stabilization of human SMN protein expressed in HEK293 cells expressing SMN2 promoter after 24 hrs by luciferase reporter gene assay				J Med Chem 60: 4594-4610 (2017) Article DOI: 10.1021/acs.jmedchem.6b01885 BindingDB Entry DOI: 10.7270/Q2DF6TM3
					More data for this Ligand-Target Pair
Survival motor neuron protein (Homo sapiens)	BDBM50242564 (CHEMBL4079330) Show SMILES CC(C)c1cc(no1)C(=O)Nc1ccccc1C Show InChI InChI=1S/C14H16N2O2/c1-9(2)13-8-12(16-18-13)14(17)15-11-7-5-4-6-10(11)3/h4-9H,1-3H3,(H,15,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Stabilization of human SMN protein expressed in HEK293 cells expressing SMN2 promoter after 24 hrs by luciferase reporter gene assay				J Med Chem 60: 4594-4610 (2017) Article DOI: 10.1021/acs.jmedchem.6b01885 BindingDB Entry DOI: 10.7270/Q2DF6TM3
					More data for this Ligand-Target Pair
Survival motor neuron protein (Homo sapiens)	BDBM50242569 (CHEMBL4068510) Show SMILES COc1ccccc1NC(=O)c1cc(on1)C(C)C Show InChI InChI=1S/C14H16N2O3/c1-9(2)13-8-11(16-19-13)14(17)15-10-6-4-5-7-12(10)18-3/h4-9H,1-3H3,(H,15,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Stabilization of human SMN protein expressed in HEK293 cells expressing SMN2 promoter after 24 hrs by luciferase reporter gene assay				J Med Chem 60: 4594-4610 (2017) Article DOI: 10.1021/acs.jmedchem.6b01885 BindingDB Entry DOI: 10.7270/Q2DF6TM3
					More data for this Ligand-Target Pair
Survival motor neuron protein (Homo sapiens)	BDBM50242570 (CHEMBL4081762) Show SMILES CC(C)c1cc(no1)C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C13H13ClN2O2/c1-8(2)12-7-11(16-18-12)13(17)15-10-5-3-9(14)4-6-10/h3-8H,1-2H3,(H,15,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Stabilization of human SMN protein expressed in HEK293 cells expressing SMN2 promoter after 24 hrs by luciferase reporter gene assay				J Med Chem 60: 4594-4610 (2017) Article DOI: 10.1021/acs.jmedchem.6b01885 BindingDB Entry DOI: 10.7270/Q2DF6TM3
					More data for this Ligand-Target Pair
Survival motor neuron protein (Homo sapiens)	BDBM50242571 (CHEMBL4059844) Show SMILES CC(C)c1cc(no1)C(=O)Nc1ccccc1Cl Show InChI InChI=1S/C13H13ClN2O2/c1-8(2)12-7-11(16-18-12)13(17)15-10-6-4-3-5-9(10)14/h3-8H,1-2H3,(H,15,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Stabilization of human SMN protein expressed in HEK293 cells expressing SMN2 promoter after 24 hrs by luciferase reporter gene assay				J Med Chem 60: 4594-4610 (2017) Article DOI: 10.1021/acs.jmedchem.6b01885 BindingDB Entry DOI: 10.7270/Q2DF6TM3
					More data for this Ligand-Target Pair
Survival motor neuron protein (Homo sapiens)	BDBM50242572 (CHEMBL4098258) Show SMILES CC(C)c1cc(no1)C(=O)Nc1ccccc1F Show InChI InChI=1S/C13H13FN2O2/c1-8(2)12-7-11(16-18-12)13(17)15-10-6-4-3-5-9(10)14/h3-8H,1-2H3,(H,15,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	260	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Stabilization of human SMN protein expressed in HEK293 cells expressing SMN2 promoter after 24 hrs by luciferase reporter gene assay				J Med Chem 60: 4594-4610 (2017) Article DOI: 10.1021/acs.jmedchem.6b01885 BindingDB Entry DOI: 10.7270/Q2DF6TM3
					More data for this Ligand-Target Pair
Survival motor neuron protein (Homo sapiens)	BDBM50242573 (CHEMBL4068807) Show SMILES CC(C)c1cc(no1)C(=O)Nc1ccccc1 Show InChI InChI=1S/C13H14N2O2/c1-9(2)12-8-11(15-17-12)13(16)14-10-6-4-3-5-7-10/h3-9H,1-2H3,(H,14,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	280	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Stabilization of human SMN protein expressed in HEK293 cells expressing SMN2 promoter after 24 hrs by luciferase reporter gene assay				J Med Chem 60: 4594-4610 (2017) Article DOI: 10.1021/acs.jmedchem.6b01885 BindingDB Entry DOI: 10.7270/Q2DF6TM3
					More data for this Ligand-Target Pair
Survival motor neuron protein (Homo sapiens)	BDBM48569 (MLS000087323 | N-(3-chlorophenyl)-5-isopropyl-isox...) Show SMILES CC(C)c1cc(no1)C(=O)Nc1cccc(Cl)c1 Show InChI InChI=1S/C13H13ClN2O2/c1-8(2)12-7-11(16-18-12)13(17)15-10-5-3-4-9(14)6-10/h3-8H,1-2H3,(H,15,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	860	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Stabilization of human SMN protein expressed in HEK293 cells expressing SMN2 promoter after 24 hrs by luciferase reporter gene assay				J Med Chem 60: 4594-4610 (2017) Article DOI: 10.1021/acs.jmedchem.6b01885 BindingDB Entry DOI: 10.7270/Q2DF6TM3
					More data for this Ligand-Target Pair
Survival motor neuron protein (Homo sapiens)	BDBM50242574 (CHEMBL4062299) Show SMILES CC(C)c1cc(no1)C(=O)Nc1ccc(F)c(Cl)c1 Show InChI InChI=1S/C13H12ClFN2O2/c1-7(2)12-6-11(17-19-12)13(18)16-8-3-4-10(15)9(14)5-8/h3-7H,1-2H3,(H,16,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Stabilization of human SMN protein expressed in HEK293 cells expressing SMN2 promoter after 24 hrs by luciferase reporter gene assay				J Med Chem 60: 4594-4610 (2017) Article DOI: 10.1021/acs.jmedchem.6b01885 BindingDB Entry DOI: 10.7270/Q2DF6TM3
					More data for this Ligand-Target Pair
Survival motor neuron protein (Homo sapiens)	BDBM50242586 (CHEMBL4092581) Show SMILES CC(C)c1onc(C(=O)Nc2ccc(F)c(Cl)c2)c1C Show InChI InChI=1S/C14H14ClFN2O2/c1-7(2)13-8(3)12(18-20-13)14(19)17-9-4-5-11(16)10(15)6-9/h4-7H,1-3H3,(H,17,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	500	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Stabilization of human SMN protein expressed in HEK293 cells expressing SMN2 promoter after 24 hrs by luciferase reporter gene assay				J Med Chem 60: 4594-4610 (2017) Article DOI: 10.1021/acs.jmedchem.6b01885 BindingDB Entry DOI: 10.7270/Q2DF6TM3
					More data for this Ligand-Target Pair
Survival motor neuron protein (Homo sapiens)	BDBM50242587 (CHEMBL4097866) Show SMILES OC1(CCC1)c1cnc(NC(=O)c2ccc(F)c(Cl)c2)s1 Show InChI InChI=1S/C14H12ClFN2O2S/c15-9-6-8(2-3-10(9)16)12(19)18-13-17-7-11(21-13)14(20)4-1-5-14/h2-3,6-7,20H,1,4-5H2,(H,17,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	290	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Stabilization of human SMN protein expressed in HEK293 cells expressing SMN2 promoter after 24 hrs by luciferase reporter gene assay				J Med Chem 60: 4594-4610 (2017) Article DOI: 10.1021/acs.jmedchem.6b01885 BindingDB Entry DOI: 10.7270/Q2DF6TM3
					More data for this Ligand-Target Pair
Survival motor neuron protein (Homo sapiens)	BDBM50242588 (CHEMBL4090149) Show SMILES CC(C)c1nc(NC(=O)c2ccc(F)c(Cl)c2)cs1 Show InChI InChI=1S/C13H12ClFN2OS/c1-7(2)13-17-11(6-19-13)16-12(18)8-3-4-10(15)9(14)5-8/h3-7H,1-2H3,(H,16,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Stabilization of human SMN protein expressed in HEK293 cells expressing SMN2 promoter after 24 hrs by luciferase reporter gene assay				J Med Chem 60: 4594-4610 (2017) Article DOI: 10.1021/acs.jmedchem.6b01885 BindingDB Entry DOI: 10.7270/Q2DF6TM3
					More data for this Ligand-Target Pair
Survival motor neuron protein (Homo sapiens)	BDBM50242589 (CHEMBL4062125) Show SMILES CC(C)c1cc(NC(=O)c2ccc(F)c(Cl)c2)on1 Show InChI InChI=1S/C13H12ClFN2O2/c1-7(2)11-6-12(19-17-11)16-13(18)8-3-4-10(15)9(14)5-8/h3-7H,1-2H3,(H,16,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Stabilization of human SMN protein expressed in HEK293 cells expressing SMN2 promoter after 24 hrs by luciferase reporter gene assay				J Med Chem 60: 4594-4610 (2017) Article DOI: 10.1021/acs.jmedchem.6b01885 BindingDB Entry DOI: 10.7270/Q2DF6TM3
					More data for this Ligand-Target Pair
Survival motor neuron protein (Homo sapiens)	BDBM50242590 (CHEMBL4089219) Show SMILES CC(C)c1cc(NC(=O)c2ccc(F)c(Cl)c2)no1 Show InChI InChI=1S/C13H12ClFN2O2/c1-7(2)11-6-12(17-19-11)16-13(18)8-3-4-10(15)9(14)5-8/h3-7H,1-2H3,(H,16,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9.90E+3	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Stabilization of human SMN protein expressed in HEK293 cells expressing SMN2 promoter after 24 hrs by luciferase reporter gene assay				J Med Chem 60: 4594-4610 (2017) Article DOI: 10.1021/acs.jmedchem.6b01885 BindingDB Entry DOI: 10.7270/Q2DF6TM3
					More data for this Ligand-Target Pair
Survival motor neuron protein (Homo sapiens)	BDBM50242591 (CHEMBL4070751) Show SMILES Fc1ccc(cc1Cl)C(=O)Nc1ncc(s1)C1CCC1 Show InChI InChI=1S/C14H12ClFN2OS/c15-10-6-9(4-5-11(10)16)13(19)18-14-17-7-12(20-14)8-2-1-3-8/h4-8H,1-3H2,(H,17,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	500	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Stabilization of human SMN protein expressed in HEK293 cells expressing SMN2 promoter after 24 hrs by luciferase reporter gene assay				J Med Chem 60: 4594-4610 (2017) Article DOI: 10.1021/acs.jmedchem.6b01885 BindingDB Entry DOI: 10.7270/Q2DF6TM3
					More data for this Ligand-Target Pair
Survival motor neuron protein (Homo sapiens)	BDBM50242592 (CHEMBL4066153) Show SMILES CC(C)c1cc(no1)C(=S)Nc1ccc(F)c(Cl)c1 Show InChI InChI=1S/C13H12ClFN2OS/c1-7(2)12-6-11(17-18-12)13(19)16-8-3-4-10(15)9(14)5-8/h3-7H,1-2H3,(H,16,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.39E+4	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Stabilization of human SMN protein expressed in HEK293 cells expressing SMN2 promoter after 24 hrs by luciferase reporter gene assay				J Med Chem 60: 4594-4610 (2017) Article DOI: 10.1021/acs.jmedchem.6b01885 BindingDB Entry DOI: 10.7270/Q2DF6TM3
					More data for this Ligand-Target Pair
Survival motor neuron protein (Homo sapiens)	BDBM50242602 (CHEMBL4073693) Show SMILES CC(C)Cc1cc(no1)C(=O)Nc1ccc(F)c(Cl)c1 Show InChI InChI=1S/C14H14ClFN2O2/c1-8(2)5-10-7-13(18-20-10)14(19)17-9-3-4-12(16)11(15)6-9/h3-4,6-8H,5H2,1-2H3,(H,17,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Stabilization of human SMN protein expressed in HEK293 cells expressing SMN2 promoter after 24 hrs by luciferase reporter gene assay				J Med Chem 60: 4594-4610 (2017) Article DOI: 10.1021/acs.jmedchem.6b01885 BindingDB Entry DOI: 10.7270/Q2DF6TM3
					More data for this Ligand-Target Pair
Survival motor neuron protein (Homo sapiens)	BDBM50242603 (CHEMBL4099244) Show SMILES CC(C)c1cc(no1)C(=O)Nc1nc2ccccc2[nH]1 Show InChI InChI=1S/C14H14N4O2/c1-8(2)12-7-11(18-20-12)13(19)17-14-15-9-5-3-4-6-10(9)16-14/h3-8H,1-2H3,(H2,15,16,17,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	260	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Stabilization of human SMN protein expressed in HEK293 cells expressing SMN2 promoter after 24 hrs by luciferase reporter gene assay				J Med Chem 60: 4594-4610 (2017) Article DOI: 10.1021/acs.jmedchem.6b01885 BindingDB Entry DOI: 10.7270/Q2DF6TM3
					More data for this Ligand-Target Pair
Survival motor neuron protein (Homo sapiens)	BDBM50242604 (CHEMBL4063645) Show SMILES CC(C)c1cc(no1)C(=O)Nc1ccc(C)cc1 Show InChI InChI=1S/C14H16N2O2/c1-9(2)13-8-12(16-18-13)14(17)15-11-6-4-10(3)5-7-11/h4-9H,1-3H3,(H,15,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Stabilization of human SMN protein expressed in HEK293 cells expressing SMN2 promoter after 24 hrs by luciferase reporter gene assay				J Med Chem 60: 4594-4610 (2017) Article DOI: 10.1021/acs.jmedchem.6b01885 BindingDB Entry DOI: 10.7270/Q2DF6TM3
					More data for this Ligand-Target Pair
Survival motor neuron protein (Homo sapiens)	BDBM50242605 (CHEMBL4089637) Show SMILES COc1cccc(NC(=O)c2cc(on2)C(C)C)c1 Show InChI InChI=1S/C14H16N2O3/c1-9(2)13-8-12(16-19-13)14(17)15-10-5-4-6-11(7-10)18-3/h4-9H,1-3H3,(H,15,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Stabilization of human SMN protein expressed in HEK293 cells expressing SMN2 promoter after 24 hrs by luciferase reporter gene assay				J Med Chem 60: 4594-4610 (2017) Article DOI: 10.1021/acs.jmedchem.6b01885 BindingDB Entry DOI: 10.7270/Q2DF6TM3
					More data for this Ligand-Target Pair
Survival motor neuron protein (Homo sapiens)	BDBM50242606 (CHEMBL4071219) Show SMILES CC(C)c1cc(no1)C(=O)Nc1cccc(F)c1 Show InChI InChI=1S/C13H13FN2O2/c1-8(2)12-7-11(16-18-12)13(17)15-10-5-3-4-9(14)6-10/h3-8H,1-2H3,(H,15,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	340	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Stabilization of human SMN protein expressed in HEK293 cells expressing SMN2 promoter after 24 hrs by luciferase reporter gene assay				J Med Chem 60: 4594-4610 (2017) Article DOI: 10.1021/acs.jmedchem.6b01885 BindingDB Entry DOI: 10.7270/Q2DF6TM3
					More data for this Ligand-Target Pair
Survival motor neuron protein (Homo sapiens)	BDBM50242552 (CHEMBL4087521) Show SMILES CC(C)c1cc(CNc2ccc(F)c(Cl)c2)no1 Show InChI InChI=1S/C13H14ClFN2O/c1-8(2)13-6-10(17-18-13)7-16-9-3-4-12(15)11(14)5-9/h3-6,8,16H,7H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.12E+4	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Stabilization of human SMN protein expressed in HEK293 cells expressing SMN2 promoter after 24 hrs by luciferase reporter gene assay				J Med Chem 60: 4594-4610 (2017) Article DOI: 10.1021/acs.jmedchem.6b01885 BindingDB Entry DOI: 10.7270/Q2DF6TM3
					More data for this Ligand-Target Pair