Compile Data Set for Download or QSAR

Found 112 hits with Last Name = 'gignoux' and Initial = 'c'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAF proto-oncogene serine/threonine-protein kinase [Y340D,Y341D] (Homo sapiens (Human))	BDBM322528 (5-[3-[4-(3-thienyl)-1H-imidazol-2-yl]chroman-6-yl]...) Show SMILES O=C1CCc2c(Oc3ccc4OCC(Cc4c3)c3nc(c[nH]3)-c3ccsc3)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent									US Patent US10183939 (2019) BindingDB Entry DOI: 10.7270/Q2QN68WX
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM322528 (5-[3-[4-(3-thienyl)-1H-imidazol-2-yl]chroman-6-yl]...) Show SMILES O=C1CCc2c(Oc3ccc4OCC(Cc4c3)c3nc(c[nH]3)-c3ccsc3)ccnc2N1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description B-RAF, RAFV600E, and C-RAF: Compounds at a concentration of 3 mM are serially diluted (e.g. 10 μl, 90 μl of 100% dimethyl sulfoxide (DMSO))...				Citation and Details BindingDB Entry DOI: 10.7270/Q2J10718
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [Y340D,Y341D] (Homo sapiens (Human))	BDBM322529 (5-[3-[4-(2-thienyl)-1H-imidazol-2-yl]chroman-6-yl]...) Show SMILES O=C1CCc2c(Oc3ccc4OCC(Cc4c3)c3nc(c[nH]3)-c3cccs3)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent									US Patent US10183939 (2019) BindingDB Entry DOI: 10.7270/Q2QN68WX
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM322529 (5-[3-[4-(2-thienyl)-1H-imidazol-2-yl]chroman-6-yl]...) Show SMILES O=C1CCc2c(Oc3ccc4OCC(Cc4c3)c3nc(c[nH]3)-c3cccs3)ccnc2N1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description B-RAF, RAFV600E, and C-RAF: Compounds at a concentration of 3 mM are serially diluted (e.g. 10 μl, 90 μl of 100% dimethyl sulfoxide (DMSO))...				Citation and Details BindingDB Entry DOI: 10.7270/Q2J10718
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [Y340D,Y341D] (Homo sapiens (Human))	BDBM322521 (5-[3-(4-phenyl-1H-imidazol-2-yl)chroman-6-yl]oxy-3...) Show SMILES O=C1CCc2c(Oc3ccc4OCC(Cc4c3)c3nc(c[nH]3)-c3ccccc3)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent									US Patent US10183939 (2019) BindingDB Entry DOI: 10.7270/Q2QN68WX
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM322521 (5-[3-(4-phenyl-1H-imidazol-2-yl)chroman-6-yl]oxy-3...) Show SMILES O=C1CCc2c(Oc3ccc4OCC(Cc4c3)c3nc(c[nH]3)-c3ccccc3)ccnc2N1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description B-RAF, RAFV600E, and C-RAF: Compounds at a concentration of 3 mM are serially diluted (e.g. 10 μl, 90 μl of 100% dimethyl sulfoxide (DMSO))...				Citation and Details BindingDB Entry DOI: 10.7270/Q2J10718
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [Y340D,Y341D] (Homo sapiens (Human))	BDBM322521 (5-[3-(4-phenyl-1H-imidazol-2-yl)chroman-6-yl]oxy-3...) Show SMILES O=C1CCc2c(Oc3ccc4OCC(Cc4c3)c3nc(c[nH]3)-c3ccccc3)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent									US Patent US10183939 (2019) BindingDB Entry DOI: 10.7270/Q2QN68WX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf [416-766,V600E] (Homo sapiens (Human))	BDBM322521 (5-[3-(4-phenyl-1H-imidazol-2-yl)chroman-6-yl]oxy-3...) Show SMILES O=C1CCc2c(Oc3ccc4OCC(Cc4c3)c3nc(c[nH]3)-c3ccccc3)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent					Assay Description To determine whether compounds bind to RAF kinases, they are tested in a competition binding assay. The Invitrogen LanthaScreen Eu binding assay invo...				US Patent US10183939 (2019) BindingDB Entry DOI: 10.7270/Q2QN68WX
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM322521 (5-[3-(4-phenyl-1H-imidazol-2-yl)chroman-6-yl]oxy-3...) Show SMILES O=C1CCc2c(Oc3ccc4OCC(Cc4c3)c3nc(c[nH]3)-c3ccccc3)ccnc2N1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description B-RAF, RAFV600E, and C-RAF: Compounds at a concentration of 3 mM are serially diluted (e.g. 10 μl, 90 μl of 100% dimethyl sulfoxide (DMSO))...				Citation and Details BindingDB Entry DOI: 10.7270/Q2J10718
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf [V600E] (Homo sapiens (Human))	BDBM322521 (5-[3-(4-phenyl-1H-imidazol-2-yl)chroman-6-yl]oxy-3...) Show SMILES O=C1CCc2c(Oc3ccc4OCC(Cc4c3)c3nc(c[nH]3)-c3ccccc3)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description B-RAF, RAFV600E, and C-RAF: Compounds at a concentration of 3 mM are serially diluted (e.g. 10 μl, 90 μl of 100% dimethyl sulfoxide (DMSO))...				Citation and Details BindingDB Entry DOI: 10.7270/Q2J10718
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf [416-766,V600E] (Homo sapiens (Human))	BDBM322528 (5-[3-[4-(3-thienyl)-1H-imidazol-2-yl]chroman-6-yl]...) Show SMILES O=C1CCc2c(Oc3ccc4OCC(Cc4c3)c3nc(c[nH]3)-c3ccsc3)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent					Assay Description To determine whether compounds bind to RAF kinases, they are tested in a competition binding assay. The Invitrogen LanthaScreen Eu binding assay invo...				US Patent US10183939 (2019) BindingDB Entry DOI: 10.7270/Q2QN68WX
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [Y340D,Y341D] (Homo sapiens (Human))	BDBM322521 (5-[3-(4-phenyl-1H-imidazol-2-yl)chroman-6-yl]oxy-3...) Show SMILES O=C1CCc2c(Oc3ccc4OCC(Cc4c3)c3nc(c[nH]3)-c3ccccc3)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent									US Patent US10183939 (2019) BindingDB Entry DOI: 10.7270/Q2QN68WX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf [V600E] (Homo sapiens (Human))	BDBM322528 (5-[3-[4-(3-thienyl)-1H-imidazol-2-yl]chroman-6-yl]...) Show SMILES O=C1CCc2c(Oc3ccc4OCC(Cc4c3)c3nc(c[nH]3)-c3ccsc3)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description B-RAF, RAFV600E, and C-RAF: Compounds at a concentration of 3 mM are serially diluted (e.g. 10 μl, 90 μl of 100% dimethyl sulfoxide (DMSO))...				Citation and Details BindingDB Entry DOI: 10.7270/Q2J10718
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM322521 (5-[3-(4-phenyl-1H-imidazol-2-yl)chroman-6-yl]oxy-3...) Show SMILES O=C1CCc2c(Oc3ccc4OCC(Cc4c3)c3nc(c[nH]3)-c3ccccc3)ccnc2N1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description B-RAF, RAFV600E, and C-RAF: Compounds at a concentration of 3 mM are serially diluted (e.g. 10 μl, 90 μl of 100% dimethyl sulfoxide (DMSO))...				Citation and Details BindingDB Entry DOI: 10.7270/Q2J10718
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf [V600E] (Homo sapiens (Human))	BDBM322529 (5-[3-[4-(2-thienyl)-1H-imidazol-2-yl]chroman-6-yl]...) Show SMILES O=C1CCc2c(Oc3ccc4OCC(Cc4c3)c3nc(c[nH]3)-c3cccs3)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description B-RAF, RAFV600E, and C-RAF: Compounds at a concentration of 3 mM are serially diluted (e.g. 10 μl, 90 μl of 100% dimethyl sulfoxide (DMSO))...				Citation and Details BindingDB Entry DOI: 10.7270/Q2J10718
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf [416-766,V600E] (Homo sapiens (Human))	BDBM322529 (5-[3-[4-(2-thienyl)-1H-imidazol-2-yl]chroman-6-yl]...) Show SMILES O=C1CCc2c(Oc3ccc4OCC(Cc4c3)c3nc(c[nH]3)-c3cccs3)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent					Assay Description To determine whether compounds bind to RAF kinases, they are tested in a competition binding assay. The Invitrogen LanthaScreen Eu binding assay invo...				US Patent US10183939 (2019) BindingDB Entry DOI: 10.7270/Q2QN68WX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf [V600E] (Homo sapiens (Human))	BDBM322521 (5-[3-(4-phenyl-1H-imidazol-2-yl)chroman-6-yl]oxy-3...) Show SMILES O=C1CCc2c(Oc3ccc4OCC(Cc4c3)c3nc(c[nH]3)-c3ccccc3)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description B-RAF, RAFV600E, and C-RAF: Compounds at a concentration of 3 mM are serially diluted (e.g. 10 μl, 90 μl of 100% dimethyl sulfoxide (DMSO))...				Citation and Details BindingDB Entry DOI: 10.7270/Q2J10718
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf [416-766,V600E] (Homo sapiens (Human))	BDBM322521 (5-[3-(4-phenyl-1H-imidazol-2-yl)chroman-6-yl]oxy-3...) Show SMILES O=C1CCc2c(Oc3ccc4OCC(Cc4c3)c3nc(c[nH]3)-c3ccccc3)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent					Assay Description To determine whether compounds bind to RAF kinases, they are tested in a competition binding assay. The Invitrogen LanthaScreen Eu binding assay invo...				US Patent US10183939 (2019) BindingDB Entry DOI: 10.7270/Q2QN68WX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf [V600E] (Homo sapiens (Human))	BDBM322521 (5-[3-(4-phenyl-1H-imidazol-2-yl)chroman-6-yl]oxy-3...) Show SMILES O=C1CCc2c(Oc3ccc4OCC(Cc4c3)c3nc(c[nH]3)-c3ccccc3)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description B-RAF, RAFV600E, and C-RAF: Compounds at a concentration of 3 mM are serially diluted (e.g. 10 μl, 90 μl of 100% dimethyl sulfoxide (DMSO))...				Citation and Details BindingDB Entry DOI: 10.7270/Q2J10718
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf [416-766,V600E] (Homo sapiens (Human))	BDBM322521 (5-[3-(4-phenyl-1H-imidazol-2-yl)chroman-6-yl]oxy-3...) Show SMILES O=C1CCc2c(Oc3ccc4OCC(Cc4c3)c3nc(c[nH]3)-c3ccccc3)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent					Assay Description To determine whether compounds bind to RAF kinases, they are tested in a competition binding assay. The Invitrogen LanthaScreen Eu binding assay invo...				US Patent US10183939 (2019) BindingDB Entry DOI: 10.7270/Q2QN68WX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf [416-766,V600E] (Homo sapiens (Human))	BDBM322518 (5-[3-(1H-benzimidazol-2-yl)chroman-6-yl]oxy-3,4-di...) Show SMILES O=C1CCc2c(Oc3ccc4OCC(Cc4c3)c3nc4ccccc4[nH]3)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<4	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent					Assay Description To determine whether compounds bind to RAF kinases, they are tested in a competition binding assay. The Invitrogen LanthaScreen Eu binding assay invo...				US Patent US10183939 (2019) BindingDB Entry DOI: 10.7270/Q2QN68WX
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [Y340D,Y341D] (Homo sapiens (Human))	BDBM322518 (5-[3-(1H-benzimidazol-2-yl)chroman-6-yl]oxy-3,4-di...) Show SMILES O=C1CCc2c(Oc3ccc4OCC(Cc4c3)c3nc4ccccc4[nH]3)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<4	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent									US Patent US10183939 (2019) BindingDB Entry DOI: 10.7270/Q2QN68WX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf [416-766,V600E] (Homo sapiens (Human))	BDBM322521 (5-[3-(4-phenyl-1H-imidazol-2-yl)chroman-6-yl]oxy-3...) Show SMILES O=C1CCc2c(Oc3ccc4OCC(Cc4c3)c3nc(c[nH]3)-c3ccccc3)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<4	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent					Assay Description To determine whether compounds bind to RAF kinases, they are tested in a competition binding assay. The Invitrogen LanthaScreen Eu binding assay invo...				US Patent US10183939 (2019) BindingDB Entry DOI: 10.7270/Q2QN68WX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf [416-766,V600E] (Homo sapiens (Human))	BDBM322521 (5-[3-(4-phenyl-1H-imidazol-2-yl)chroman-6-yl]oxy-3...) Show SMILES O=C1CCc2c(Oc3ccc4OCC(Cc4c3)c3nc(c[nH]3)-c3ccccc3)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<4	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent					Assay Description To determine whether compounds bind to RAF kinases, they are tested in a competition binding assay. The Invitrogen LanthaScreen Eu binding assay invo...				US Patent US10183939 (2019) BindingDB Entry DOI: 10.7270/Q2QN68WX
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [Y340D,Y341D] (Homo sapiens (Human))	BDBM322521 (5-[3-(4-phenyl-1H-imidazol-2-yl)chroman-6-yl]oxy-3...) Show SMILES O=C1CCc2c(Oc3ccc4OCC(Cc4c3)c3nc(c[nH]3)-c3ccccc3)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<4	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent									US Patent US10183939 (2019) BindingDB Entry DOI: 10.7270/Q2QN68WX
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [Y340D,Y341D] (Homo sapiens (Human))	BDBM322521 (5-[3-(4-phenyl-1H-imidazol-2-yl)chroman-6-yl]oxy-3...) Show SMILES O=C1CCc2c(Oc3ccc4OCC(Cc4c3)c3nc(c[nH]3)-c3ccccc3)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<4	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent									US Patent US10183939 (2019) BindingDB Entry DOI: 10.7270/Q2QN68WX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf [416-766,V600E] (Homo sapiens (Human))	BDBM322525 (5-[3[4-(4-pyridyl)-1H-imidazol-2-yl]chroman-6-yl]o...) Show SMILES O=C1CCc2c(Oc3ccc4OCC(Cc4c3)c3nc(c[nH]3)-c3ccncc3)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<4	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent					Assay Description To determine whether compounds bind to RAF kinases, they are tested in a competition binding assay. The Invitrogen LanthaScreen Eu binding assay invo...				US Patent US10183939 (2019) BindingDB Entry DOI: 10.7270/Q2QN68WX
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [Y340D,Y341D] (Homo sapiens (Human))	BDBM322527 (5-[3-(4-tert-butyl-1H-imidazol-2-yl)chroman-6-yl]o...) Show SMILES CC(C)(C)c1c[nH]c(n1)C1COc2ccc(Oc3ccnc4NC(=O)CCc34)cc2C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<4	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent									US Patent US10183939 (2019) BindingDB Entry DOI: 10.7270/Q2QN68WX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf [416-766,V600E] (Homo sapiens (Human))	BDBM322528 (5-[3-[4-(3-thienyl)-1H-imidazol-2-yl]chroman-6-yl]...) Show SMILES O=C1CCc2c(Oc3ccc4OCC(Cc4c3)c3nc(c[nH]3)-c3ccsc3)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<4	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent					Assay Description To determine whether compounds bind to RAF kinases, they are tested in a competition binding assay. The Invitrogen LanthaScreen Eu binding assay invo...				US Patent US10183939 (2019) BindingDB Entry DOI: 10.7270/Q2QN68WX
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [Y340D,Y341D] (Homo sapiens (Human))	BDBM322528 (5-[3-[4-(3-thienyl)-1H-imidazol-2-yl]chroman-6-yl]...) Show SMILES O=C1CCc2c(Oc3ccc4OCC(Cc4c3)c3nc(c[nH]3)-c3ccsc3)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<4	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent									US Patent US10183939 (2019) BindingDB Entry DOI: 10.7270/Q2QN68WX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf [416-766,V600E] (Homo sapiens (Human))	BDBM322529 (5-[3-[4-(2-thienyl)-1H-imidazol-2-yl]chroman-6-yl]...) Show SMILES O=C1CCc2c(Oc3ccc4OCC(Cc4c3)c3nc(c[nH]3)-c3cccs3)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<4	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent					Assay Description To determine whether compounds bind to RAF kinases, they are tested in a competition binding assay. The Invitrogen LanthaScreen Eu binding assay invo...				US Patent US10183939 (2019) BindingDB Entry DOI: 10.7270/Q2QN68WX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf [416-766,V600E] (Homo sapiens (Human))	BDBM322530 (5-[3-[5-(2-chlorophenyl)-1H-imidazol-2-yl]chroman-...) Show SMILES Clc1ccccc1-c1cnc([nH]1)C1COc2ccc(Oc3ccnc4NC(=O)CCc34)cc2C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	<4	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent					Assay Description To determine whether compounds bind to RAF kinases, they are tested in a competition binding assay. The Invitrogen LanthaScreen Eu binding assay invo...				US Patent US10183939 (2019) BindingDB Entry DOI: 10.7270/Q2QN68WX
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [Y340D,Y341D] (Homo sapiens (Human))	BDBM322530 (5-[3-[5-(2-chlorophenyl)-1H-imidazol-2-yl]chroman-...) Show SMILES Clc1ccccc1-c1cnc([nH]1)C1COc2ccc(Oc3ccnc4NC(=O)CCc34)cc2C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	<4	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent									US Patent US10183939 (2019) BindingDB Entry DOI: 10.7270/Q2QN68WX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf [416-766,V600E] (Homo sapiens (Human))	BDBM322531 (5-[3-[5-(3-chlorophenyl)-1H-imidazol-2-yl]chroman-...) Show SMILES Clc1cccc(c1)-c1cnc([nH]1)C1COc2ccc(Oc3ccnc4NC(=O)CCc34)cc2C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<4	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent					Assay Description To determine whether compounds bind to RAF kinases, they are tested in a competition binding assay. The Invitrogen LanthaScreen Eu binding assay invo...				US Patent US10183939 (2019) BindingDB Entry DOI: 10.7270/Q2QN68WX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf [416-766,V600E] (Homo sapiens (Human))	BDBM322532 (5-[3-[4-(benzofuran-3-yl)-1H-imidazol-2-yl]chroman...) Show SMILES O=C1CCc2c(Oc3ccc4OCC(Cc4c3)c3nc(c[nH]3)-c3coc4ccccc34)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<4	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent					Assay Description To determine whether compounds bind to RAF kinases, they are tested in a competition binding assay. The Invitrogen LanthaScreen Eu binding assay invo...				US Patent US10183939 (2019) BindingDB Entry DOI: 10.7270/Q2QN68WX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf [416-766,V600E] (Homo sapiens (Human))	BDBM322533 (5-[3-[5-(3-pyridyl)-1H-imidazol-2-yl]chroman-6-yl]...) Show SMILES O=C1CCc2c(Oc3ccc4OCC(Cc4c3)c3ncc([nH]3)-c3cccnc3)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<4	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent					Assay Description To determine whether compounds bind to RAF kinases, they are tested in a competition binding assay. The Invitrogen LanthaScreen Eu binding assay invo...				US Patent US10183939 (2019) BindingDB Entry DOI: 10.7270/Q2QN68WX
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [Y340D,Y341D] (Homo sapiens (Human))	BDBM322533 (5-[3-[5-(3-pyridyl)-1H-imidazol-2-yl]chroman-6-yl]...) Show SMILES O=C1CCc2c(Oc3ccc4OCC(Cc4c3)c3ncc([nH]3)-c3cccnc3)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<4	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent									US Patent US10183939 (2019) BindingDB Entry DOI: 10.7270/Q2QN68WX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf [416-766,V600E] (Homo sapiens (Human))	BDBM322535 (5-[3-[5-(4-fluorophenyl)-1H-imidazol-2-yl]chroman-...) Show SMILES Fc1ccc(cc1)-c1cnc([nH]1)C1COc2ccc(Oc3ccnc4NC(=O)CCc34)cc2C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<4	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent					Assay Description To determine whether compounds bind to RAF kinases, they are tested in a competition binding assay. The Invitrogen LanthaScreen Eu binding assay invo...				US Patent US10183939 (2019) BindingDB Entry DOI: 10.7270/Q2QN68WX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf [416-766,V600E] (Homo sapiens (Human))	BDBM322536 (5-[3-[5-(1,3-benzodioxol-5-yl)-1H-imidazol-2-yl]ch...) Show SMILES O=C1CCc2c(Oc3ccc4OCC(Cc4c3)c3ncc([nH]3)-c3ccc4OCOc4c3)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<4	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent					Assay Description To determine whether compounds bind to RAF kinases, they are tested in a competition binding assay. The Invitrogen LanthaScreen Eu binding assay invo...				US Patent US10183939 (2019) BindingDB Entry DOI: 10.7270/Q2QN68WX
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [Y340D,Y341D] (Homo sapiens (Human))	BDBM322536 (5-[3-[5-(1,3-benzodioxol-5-yl)-1H-imidazol-2-yl]ch...) Show SMILES O=C1CCc2c(Oc3ccc4OCC(Cc4c3)c3ncc([nH]3)-c3ccc4OCOc4c3)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<4	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent									US Patent US10183939 (2019) BindingDB Entry DOI: 10.7270/Q2QN68WX
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [Y340D,Y341D] (Homo sapiens (Human))	BDBM322537 (5-[3-[5-(2,3-dihydro-1,4-benzodioxin-6-yl)-1H-imid...) Show SMILES O=C1CCc2c(Oc3ccc4OCC(Cc4c3)c3ncc([nH]3)-c3ccc4OCCOc4c3)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<4	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent									US Patent US10183939 (2019) BindingDB Entry DOI: 10.7270/Q2QN68WX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf [416-766,V600E] (Homo sapiens (Human))	BDBM322540 (5-[3-(5-phenyl-1H-pyrazol-3-yl)chroman-6-yl]oxy-3,...) Show SMILES O=C1CCc2c(Oc3ccc4OCC(Cc4c3)c3cc([nH]n3)-c3ccccc3)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<4	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent					Assay Description To determine whether compounds bind to RAF kinases, they are tested in a competition binding assay. The Invitrogen LanthaScreen Eu binding assay invo...				US Patent US10183939 (2019) BindingDB Entry DOI: 10.7270/Q2QN68WX
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [Y340D,Y341D] (Homo sapiens (Human))	BDBM322540 (5-[3-(5-phenyl-1H-pyrazol-3-yl)chroman-6-yl]oxy-3,...) Show SMILES O=C1CCc2c(Oc3ccc4OCC(Cc4c3)c3cc([nH]n3)-c3ccccc3)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<4	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent									US Patent US10183939 (2019) BindingDB Entry DOI: 10.7270/Q2QN68WX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf [416-766,V600E] (Homo sapiens (Human))	BDBM322541 (5-[[(3S)-3-(4-phenyl-1H-imidazol-2-yl)-2,3-dihydro...) Show SMILES O=C1CCc2c(Oc3ccc4OC[C@@H](Oc4c3)c3nc(c[nH]3)-c3ccccc3)ccnc2N1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<4	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent					Assay Description To determine whether compounds bind to RAF kinases, they are tested in a competition binding assay. The Invitrogen LanthaScreen Eu binding assay invo...				US Patent US10183939 (2019) BindingDB Entry DOI: 10.7270/Q2QN68WX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf [416-766,V600E] (Homo sapiens (Human))	BDBM322542 (5-[[(3R)-3-(4-phenyl-1H-imidazol-2-yl)-2,3-dihydro...) Show SMILES O=C1CCc2c(Oc3ccc4OC[C@H](Oc4c3)c3nc(c[nH]3)-c3ccccc3)ccnc2N1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<4	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent					Assay Description To determine whether compounds bind to RAF kinases, they are tested in a competition binding assay. The Invitrogen LanthaScreen Eu binding assay invo...				US Patent US10183939 (2019) BindingDB Entry DOI: 10.7270/Q2QN68WX
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [Y340D,Y341D] (Homo sapiens (Human))	BDBM322542 (5-[[(3R)-3-(4-phenyl-1H-imidazol-2-yl)-2,3-dihydro...) Show SMILES O=C1CCc2c(Oc3ccc4OC[C@H](Oc4c3)c3nc(c[nH]3)-c3ccccc3)ccnc2N1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<4	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent									US Patent US10183939 (2019) BindingDB Entry DOI: 10.7270/Q2QN68WX
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf [416-766,V600E] (Homo sapiens (Human))	BDBM322521 (5-[3-(4-phenyl-1H-imidazol-2-yl)chroman-6-yl]oxy-3...) Show SMILES O=C1CCc2c(Oc3ccc4OCC(Cc4c3)c3nc(c[nH]3)-c3ccccc3)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<4	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent					Assay Description To determine whether compounds bind to RAF kinases, they are tested in a competition binding assay. The Invitrogen LanthaScreen Eu binding assay invo...				US Patent US10183939 (2019) BindingDB Entry DOI: 10.7270/Q2QN68WX
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [Y340D,Y341D] (Homo sapiens (Human))	BDBM322531 (5-[3-[5-(3-chlorophenyl)-1H-imidazol-2-yl]chroman-...) Show SMILES Clc1cccc(c1)-c1cnc([nH]1)C1COc2ccc(Oc3ccnc4NC(=O)CCc34)cc2C1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<4	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent									US Patent US10183939 (2019) BindingDB Entry DOI: 10.7270/Q2QN68WX
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [Y340D,Y341D] (Homo sapiens (Human))	BDBM322521 (5-[3-(4-phenyl-1H-imidazol-2-yl)chroman-6-yl]oxy-3...) Show SMILES O=C1CCc2c(Oc3ccc4OCC(Cc4c3)c3nc(c[nH]3)-c3ccccc3)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<4	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent									US Patent US10183939 (2019) BindingDB Entry DOI: 10.7270/Q2QN68WX
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [Y340D,Y341D] (Homo sapiens (Human))	BDBM322525 (5-[3[4-(4-pyridyl)-1H-imidazol-2-yl]chroman-6-yl]o...) Show SMILES O=C1CCc2c(Oc3ccc4OCC(Cc4c3)c3nc(c[nH]3)-c3ccncc3)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<4	n/a	n/a	n/a	n/a	n/a	n/a
Redx Pharma PLC US Patent									US Patent US10183939 (2019) BindingDB Entry DOI: 10.7270/Q2QN68WX
					More data for this Ligand-Target Pair

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