Compile Data Set for Download or QSAR

Found 1156 hits with Last Name = 'hamada' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 4F2 (Homo sapiens (Human))	BDBM558265 (N-Methyl-3-[[methyl-[3-[[6-(1-H-pyrazol-5-yl)-3-py...) Show SMILES CC(=O)Oc1cc(CO)ccc1F Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair
Cytochrome P450 4F2 (Homo sapiens (Human))	BDBM558426 (Methyl 4-hydroxy-4-[3-[[6-(1-H-pyrazol-5-yl)-3-pyr...) Show SMILES COC(=O)N1CCC(O)(CC1)c1cccc(COc2ccc(nc2)-c2ccn[nH]2)c1 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair
Cytochrome P450 4F2 (Homo sapiens (Human))	BDBM558427 (US11365192, Example 51-2) Show SMILES CCOC(=O)C(C)(C)n1ccc(CCCCO)n1 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair
Cytochrome P450 4F2 (Homo sapiens (Human))	BDBM558428 (1-[4-Hydroxy-4-[3-[[6-(1-H-pyrazol-5-yl)-3-pyridin...) Show SMILES CC(=O)N1CCC(O)(CC1)c1cccc(COc2ccc(nc2)-c2ccn[nH]2)c1 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair
Cytochrome P450 4F2 (Homo sapiens (Human))	BDBM558214 (2,3-Difluoro-5-[3-[[6-(1H-pyrazol-5-yl)-3-pyridiny...) Show SMILES Oc1cc(CCCOc2ccc(nc2)-c2ccn[nH]2)cc(F)c1F Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair
Cytochrome P450 4F2 (Homo sapiens (Human))	BDBM558439 (N-Methyl-N-[[3-[[6-(1H-pyrazol-5-yl)-3-pyridinyl]o...) Show SMILES CN(CC12CC(COc3ccc(nc3)-c3ccn[nH]3)(C1)C2)S(C)(=O)=O Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair
Cytochrome P450 4A11 (Homo sapiens)	BDBM558313 (2-[3-[[6-(5-Isothiazolyl)-3-pyridinyl]oxymethyl]ph...) Show SMILES OC(=O)Cc1cccc(COc2ccc(nc2)-c2ccns2)c1 Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair
Cytochrome P450 4F2 (Homo sapiens (Human))	BDBM558338 (US11365192, Example 42-16) Show SMILES CN(C)C(=O)\C=C\c1cccc(COc2ccc(nc2)-c2ccn[nH]2)c1 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM649470 (US11890288, Compound 11) Show SMILES COC(=O)C[C@@H]1N=C(c2c(C)c(C)sc2-n2c(C)nnc12)c1ccc(cc1)-c1ccc(cc1)C(=O)NCCc1ccc(cc1)S(=O)(=O)Nc1ccc(C)c2c(c[nH]c12)C#N |r,c:6| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 4F2 (Homo sapiens (Human))	BDBM558218 (2-Methyl-5-[[6-(1H-pyrazol-5-yl)-3-pyridinyl]oxyme...) Show SMILES Cc1ccc(COc2ccc(nc2)-c2ccn[nH]2)cc1O Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair
Cytochrome P450 4F2 (Homo sapiens (Human))	BDBM558269 (US11365192, Example 23-6) Show SMILES Fc1ccc(NS(=O)(=O)c2ccc(COc3ccc(nc3)-c3ccn[nH]3)cc2)cc1 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair
Cytochrome P450 4F2 (Homo sapiens (Human))	BDBM50591500 (CHEMBL5195099) Show SMILES N#Cc1ccc(COc2ccc(nc2)-c2ccn[nH]2)cc1 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01089 BindingDB Entry DOI: 10.7270/Q2MK6HW6
					More data for this Ligand-Target Pair
Cytochrome P450 4A11 (Homo sapiens)	BDBM558316 (US11365192, Example 40-2) Show SMILES CC(C)OC(=O)c1ccc(CCO)cc1 Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair
Cytochrome P450 4F2 (Homo sapiens (Human))	BDBM558216 (US11365192, Example 11-3) Show SMILES CCOC(=O)c1cc(CBr)ccc1Cl Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair
Cytochrome P450 4A11 (Homo sapiens)	BDBM558552 (US11365192, Example 75-7 | US11365192, Example 75-...) Show SMILES OC(=O)C1CCc2ccc(COc3ccc(nc3)-c3[nH]ncc3Cl)cc2O1 Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair
Cytochrome P450 4F2 (Homo sapiens (Human))	BDBM558188 (1-Acetyl-4-[8-[[6-(1H-pyrazol-5-yl)-3-pyridinyl]ox...) Show SMILES CC(=O)N1CCC(CCCCCCCCOc2ccc(nc2)-c2ccn[nH]2)(CC1)C(O)=O Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair
Cytochrome P450 4A11 (Homo sapiens)	BDBM558451 (1,1,1-Trifluoro-N-[[3-[[6-(1-H-pyrazol-5-yl)-3-pyr...) Show SMILES FC(F)(F)S(=O)(=O)NCc1cccc(COc2ccc(nc2)-c2ccn[nH]2)c1 Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair
Cytochrome P450 4A11 (Homo sapiens)	BDBM558443 (2,2-Difluoro-2-[3-[[6-(1H-pyrazol-5-yl)-3-pyridiny...) Show SMILES OC(=O)C(F)(F)c1cccc(COc2ccc(nc2)-c2ccn[nH]2)c1 Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair
Cytochrome P450 4F2 (Homo sapiens (Human))	BDBM558158 (US11365192, Example 1-63) Show SMILES CC(C)(CCCCCCCCOc1ccc(nc1)-c1ccn[nH]1)C(O)=O Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair
Cytochrome P450 4A11 (Homo sapiens)	BDBM558294 (3-[3-[[6-(1H-Pyrazol-5-yl)-3-pyridinyl]oxymethyl]p...) Show SMILES OC(=O)c1cccc(c1)-c1cccc(COc2ccc(nc2)-c2ccn[nH]2)c1 Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair
Cytochrome P450 4F2 (Homo sapiens (Human))	BDBM558529 (US11365192, Example 72-6) Show SMILES OC(=O)C1(CCCCCCCCOc2ccc(nc2)-c2ccn[nH]2)CCS(=O)(=O)CC1 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair
Cytochrome P450 4A11 (Homo sapiens)	BDBM558114 (US11365192, Example 1-19) Show SMILES OC(=O)c1cccc(CCCCOc2ccc(nc2)-c2ccn[nH]2)c1 Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair
Cytochrome P450 4A11 (Homo sapiens)	BDBM558295 (US11365192, Example 31-2) Show SMILES OC(=O)c1ccc(cc1)-c1cccc(COc2ccc(nc2)-c2ccn[nH]2)c1 Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair
Cytochrome P450 4A11 (Homo sapiens)	BDBM558315 (2-[3-[[6-(5-Oxazolyl)-3-pyridinyl]oxymethyl]phenyl...) Show SMILES OC(=O)Cc1cccc(COc2ccc(nc2)-c2cnco2)c1 Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair
Cytochrome P450 4F2 (Homo sapiens (Human))	BDBM558440 (1,1,1-Trifluoro-3-[3-[[6-(1H-pyrazol-5-yl)-3-pyrid...) Show SMILES OC(Cc1cccc(COc2ccc(nc2)-c2ccn[nH]2)c1)C(F)(F)F Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair
Cytochrome P450 4F2 (Homo sapiens (Human))	BDBM558219 (US11365192, Example 12-2) Show SMILES Oc1cc(COc2ccc(nc2)-c2ccn[nH]2)ccc1F Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair
Cytochrome P450 4A11 (Homo sapiens)	BDBM558311 (2-[3-[[6-(1H-Pyrazol-4-yl)-3-pyridinyl]oxymethyl]p...) Show SMILES CCOC(=O)C(C)(C)OCCCCOCCCCO Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair
Cytochrome P450 4F2 (Homo sapiens (Human))	BDBM558342 (US11365192, Example 42-20) Show SMILES Fc1cc(OCc2cccc(CCC(=O)NC3COC3)c2)cnc1-c1ccn[nH]1 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Mus musculus)	BDBM50038202 (5-((2,5-dihydroxybenzyl)(2-hydroxybenzyl)amino)-2-...) Show SMILES OC(=O)c1cc(ccc1O)N(Cc1ccccc1O)Cc1cc(O)ccc1O Show InChI InChI=1S/C21H19NO6/c23-16-6-8-19(25)14(9-16)12-22(11-13-3-1-2-4-18(13)24)15-5-7-20(26)17(10-15)21(27)28/h1-10,23-26H,11-12H2,(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of mouse EGFR by liquid scintillation counting				Citation and Details Article DOI: 10.1021/np50066a009 BindingDB Entry DOI: 10.7270/Q2BP05JV
					More data for this Ligand-Target Pair
Cytochrome P450 4A11 (Homo sapiens)	BDBM558231 (US11365192, Example 18-2) Show SMILES OC(=O)c1ccc(nc1)-c1cccc(COc2ccc(nc2)-c2ccn[nH]2)c1 Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair
Cytochrome P450 4F2 (Homo sapiens (Human))	BDBM558533 (1,1-Dioxo-3-[8-[6-(1H-pyrazol-5-yl)pyridin-3-yl]ox...) Show SMILES OC(=O)C1(CCCCCCCCOc2ccc(nc2)-c2ccn[nH]2)CS(=O)(=O)C1 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair
Cytochrome P450 4F2 (Homo sapiens (Human))	BDBM558339 (US11365192, Example 42-17) Show SMILES Fc1cc(OCc2cccc(CCC(=O)N3CCC3)c2)cnc1-c1ccn[nH]1 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair
Cytochrome P450 4F2 (Homo sapiens (Human))	BDBM558326 (US11365192, Example 42-4) Show SMILES CNC(=O)Cc1cccc(COc2ccc(nc2)-c2ccn[nH]2)c1 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair
Cytochrome P450 4A11 (Homo sapiens)	BDBM558297 (US11365192, Example 31-4) Show SMILES OC(=O)c1cncc(c1)-c1cccc(COc2ccc(nc2)-c2ccn[nH]2)c1 Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair
Cytochrome P450 4A11 (Homo sapiens)	BDBM558265 (N-Methyl-3-[[methyl-[3-[[6-(1-H-pyrazol-5-yl)-3-py...) Show SMILES CC(=O)Oc1cc(CO)ccc1F Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM242558 (US9422240, 1-353) Show SMILES OC(=O)CNC(=O)C1=C(O)CCN(Cc2ccc(Oc3ccc(Cl)cc3)nc2)C1=O |c:7| Show InChI InChI=1S/C20H18ClN3O6/c21-13-2-4-14(5-3-13)30-16-6-1-12(9-22-16)11-24-8-7-15(25)18(20(24)29)19(28)23-10-17(26)27/h1-6,9,25H,7-8,10-11H2,(H,23,28)(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human PHD2 using FITC-HIF1-alpha as substrate after 10 mins in presence of 2-oxoglutarate by fluorescence polarization assay				Bioorg Med Chem Lett 28: 1725-1730 (2018) Article DOI: 10.1016/j.bmcl.2018.04.039 BindingDB Entry DOI: 10.7270/Q2ZC85C4
					More data for this Ligand-Target Pair
Cytochrome P450 4F2 (Homo sapiens (Human))	BDBM558222 (US11365192, Example 13-2) Show SMILES Oc1ccccc1CCOc1ccc(nc1)-c1ccn[nH]1 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair
Cytochrome P450 4A11 (Homo sapiens)	BDBM558230 (6-[3-[[6-(1H-Pyrazol-5-yl)-3-pyridinyl]oxymethyl]p...) Show SMILES OC(=O)c1cccc(n1)-c1cccc(COc2ccc(nc2)-c2ccn[nH]2)c1 Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair
Cytochrome P450 4A11 (Homo sapiens)	BDBM558113 (US11365192, Example 1-18) Show SMILES OC(=O)c1ccc(CCCCOc2ccc(nc2)-c2ccn[nH]2)cc1 Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair
Cytochrome P450 4F2 (Homo sapiens (Human))	BDBM558527 (US11365192, Example 72-4) Show SMILES OC(=O)C1(CCCCCCCCOc2ccc(nc2)-c2ccn[nH]2)CCOC1 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair
Cytochrome P450 4A11 (Homo sapiens)	BDBM558200 (US11365192, Example 8-11) Show SMILES OC(=O)c1cc(ccn1)-c1cccc(COc2ccc(nc2)-c2ccn[nH]2)c1 Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM242568 (US9422240, 1-378) Show SMILES CC(C)c1ccc(Oc2ccc(CN3CCC(O)=C(C(=O)NCC(O)=O)C3=O)cn2)cc1 |t:17| Show InChI InChI=1S/C23H25N3O6/c1-14(2)16-4-6-17(7-5-16)32-19-8-3-15(11-24-19)13-26-10-9-18(27)21(23(26)31)22(30)25-12-20(28)29/h3-8,11,14,27H,9-10,12-13H2,1-2H3,(H,25,30)(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	7.5	n/a
TAISHO PHARMACEUTICAL CO., LTD US Patent					Assay Description The enzyme and the substrate were each diluted with a 50 mM tris-hydrochloric acid buffer (pH 7.5) containing 12.5 mM KCl, 3.75 mM MgCl2, 25 μM ...				US Patent US9422240 (2016) BindingDB Entry DOI: 10.7270/Q24B307K
					More data for this Ligand-Target Pair
Cytochrome P450 4A11 (Homo sapiens)	BDBM558530 (US11365192, Example 72-7) Show SMILES OC(=O)C1(Cc2cccc(COc3ccc(nc3)-c3ccn[nH]3)c2F)CC1 Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair
Cytochrome P450 4F2 (Homo sapiens (Human))	BDBM50591501 (CHEMBL5183418) Show SMILES N#Cc1cccc(COc2ccc(nc2)-c2ccn[nH]2)c1 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01089 BindingDB Entry DOI: 10.7270/Q2MK6HW6
					More data for this Ligand-Target Pair
Cytochrome P450 4A11 (Homo sapiens)	BDBM558278 (US11365192, Example 27-2) Show SMILES CC(O)(c1cccc(COc2ccc(nc2)-c2ccn[nH]2)c1)C(F)(F)F Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair
Cytochrome P450 4A11 (Homo sapiens)	BDBM558170 (3-[2-[2-[[6-(1H-Pyrazol-5-yl)-3-pyridinyl]oxy]ethy...) Show SMILES OC(=O)CCc1ccccc1CCOc1ccc(nc1)-c1ccn[nH]1 Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair
Cytochrome P450 4A11 (Homo sapiens)	BDBM558244 ((2E)-3-[3-[[[6-(1H-Pyrazol-5-yl)pyridin-3-yl]oxy]m...) Show SMILES OC(=O)\C=C\c1cccc(COc2ccc(nc2)-c2ccn[nH]2)c1 Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM242567 (US9422240, 1-377) Show SMILES CCCc1ccc(Oc2ccc(CN3CCC(O)=C(C(=O)NCC(O)=O)C3=O)cn2)cc1 |t:17| Show InChI InChI=1S/C23H25N3O6/c1-2-3-15-4-7-17(8-5-15)32-19-9-6-16(12-24-19)14-26-11-10-18(27)21(23(26)31)22(30)25-13-20(28)29/h4-9,12,27H,2-3,10-11,13-14H2,1H3,(H,25,30)(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	7.5	n/a
TAISHO PHARMACEUTICAL CO., LTD US Patent					Assay Description The enzyme and the substrate were each diluted with a 50 mM tris-hydrochloric acid buffer (pH 7.5) containing 12.5 mM KCl, 3.75 mM MgCl2, 25 μM ...				US Patent US9422240 (2016) BindingDB Entry DOI: 10.7270/Q24B307K
					More data for this Ligand-Target Pair
Cytochrome P450 4A11 (Homo sapiens)	BDBM558531 (US11365192, Example 72-8) Show SMILES OC(=O)C1(Cc2cccc(CCOc3ccc(nc3)-c3ccn[nH]3)c2F)CC1 Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair
Cytochrome P450 4F2 (Homo sapiens (Human))	BDBM558332 (US11365192, Example 42-10) Show SMILES CCCNC(=O)CCc1cccc(COc2ccc(nc2)-c2ccn[nH]2)c1 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN98V9
					More data for this Ligand-Target Pair

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