Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutamate receptor 3 (RAT) | BDBM50059672 ((S)-2-AMINO-3-[3-HYDROXY-5-(2-METHYL-2H-TETRAZOL-5...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Turin Curated by ChEMBL | Assay Description Displacement of (RS)-[3H]AMPA from recombinant rat GluA3 expressed in baculovirus infected Sf9 insect cell membranes | J Med Chem 62: 4467-4482 (2019) Article DOI: 10.1021/acs.jmedchem.8b01986 BindingDB Entry DOI: 10.7270/Q2NG4V06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 4 (Rattus norvegicus) | BDBM50059672 ((S)-2-AMINO-3-[3-HYDROXY-5-(2-METHYL-2H-TETRAZOL-5...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Turin Curated by ChEMBL | Assay Description Displacement of (RS)-[3H]AMPA from recombinant rat GluA4 expressed in baculovirus infected Sf9 insect cell membranes | J Med Chem 62: 4467-4482 (2019) Article DOI: 10.1021/acs.jmedchem.8b01986 BindingDB Entry DOI: 10.7270/Q2NG4V06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Rattus norvegicus) | BDBM50059672 ((S)-2-AMINO-3-[3-HYDROXY-5-(2-METHYL-2H-TETRAZOL-5...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Turin Curated by ChEMBL | Assay Description Displacement of (RS)-[3H]AMPA from recombinant rat GluA2(R) expressed in baculovirus infected Sf9 insect cell membranes | J Med Chem 62: 4467-4482 (2019) Article DOI: 10.1021/acs.jmedchem.8b01986 BindingDB Entry DOI: 10.7270/Q2NG4V06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 1 (Rattus norvegicus (Rat)) | BDBM50059672 ((S)-2-AMINO-3-[3-HYDROXY-5-(2-METHYL-2H-TETRAZOL-5...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 5.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Turin Curated by ChEMBL | Assay Description Displacement of (RS)-[3H]AMPA from recombinant rat GluA1 expressed in baculovirus infected Sf9 insect cell membranes | J Med Chem 62: 4467-4482 (2019) Article DOI: 10.1021/acs.jmedchem.8b01986 BindingDB Entry DOI: 10.7270/Q2NG4V06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Rattus norvegicus) | BDBM50512945 ((S)-AMPA) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase KEGG PC cid PC sid PDB UniChem | PDB Article PubMed | 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Turin Curated by ChEMBL | Assay Description Displacement of (RS)-[3H]AMPA from recombinant rat GluA2(R) expressed in baculovirus infected Sf9 insect cell membranes | J Med Chem 62: 4467-4482 (2019) Article DOI: 10.1021/acs.jmedchem.8b01986 BindingDB Entry DOI: 10.7270/Q2NG4V06 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor 3 (RAT) | BDBM50512945 ((S)-AMPA) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase KEGG PC cid PC sid PDB UniChem | PDB Article PubMed | 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Turin Curated by ChEMBL | Assay Description Displacement of (RS)-[3H]AMPA from recombinant rat GluA3 expressed in baculovirus infected Sf9 insect cell membranes | J Med Chem 62: 4467-4482 (2019) Article DOI: 10.1021/acs.jmedchem.8b01986 BindingDB Entry DOI: 10.7270/Q2NG4V06 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor 1 (Rattus norvegicus (Rat)) | BDBM50512945 ((S)-AMPA) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase KEGG PC cid PC sid PDB UniChem | Article PubMed | 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Turin Curated by ChEMBL | Assay Description Displacement of (RS)-[3H]AMPA from recombinant rat GluA1 expressed in baculovirus infected Sf9 insect cell membranes | J Med Chem 62: 4467-4482 (2019) Article DOI: 10.1021/acs.jmedchem.8b01986 BindingDB Entry DOI: 10.7270/Q2NG4V06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 4 (Rattus norvegicus) | BDBM50512945 ((S)-AMPA) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase KEGG PC cid PC sid PDB UniChem | PDB Article PubMed | 40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Turin Curated by ChEMBL | Assay Description Displacement of (RS)-[3H]AMPA from recombinant rat GluA4 expressed in baculovirus infected Sf9 insect cell membranes | J Med Chem 62: 4467-4482 (2019) Article DOI: 10.1021/acs.jmedchem.8b01986 BindingDB Entry DOI: 10.7270/Q2NG4V06 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor 2 (Rattus norvegicus) | BDBM50318264 ((+)-2-Amino-3-(4-hydroxy-1,2,5-oxadiazol-3-yl)prop...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 43 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Torino Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from rat iGluR2 receptor expressed in Sf9 cells baculovirus system after 1 to 2 hrs by liquid scintillation counting | J Med Chem 53: 4110-8 (2010) Article DOI: 10.1021/jm1001452 BindingDB Entry DOI: 10.7270/Q2RR206G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Rattus norvegicus) | BDBM50318264 ((+)-2-Amino-3-(4-hydroxy-1,2,5-oxadiazol-3-yl)prop...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 43 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Torino Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from rat iGluR2 receptor expressed in Sf9 cells baculovirus system after 1 to 2 hrs by liquid scintillation counting | J Med Chem 53: 4110-8 (2010) Article DOI: 10.1021/jm1001452 BindingDB Entry DOI: 10.7270/Q2RR206G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2A (Rattus norvegicus (Rat)) | BDBM213889 (5,7-Dichlorokynurenic acid (5,7-DCKA)) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | 65 | -41.0 | 92 | n/a | n/a | n/a | n/a | 7.4 | 25 |
University of Copenhagen | Assay Description Two-electrode voltage clamp (TEVC) recordings were performed on Xenopus oocytes at room temperature 3-6 days postinjection using an OC-725C TEVC ampl... | J Biol Chem 288: 33124-35 (2013) Article DOI: 10.1074/jbc.M113.480210 BindingDB Entry DOI: 10.7270/Q2MG7NB1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 1 (RAT) | BDBM17657 ((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Torino Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from rat iGluR5 receptor expressed in Sf9 cells baculovirus system after 1 to 2 hrs by liquid scintillation counting | J Med Chem 53: 4110-8 (2010) Article DOI: 10.1021/jm1001452 BindingDB Entry DOI: 10.7270/Q2RR206G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 4 (Rattus norvegicus) | BDBM50211399 ((RS)-2-amino-3-[3-hydroxy-5-(2-benzyl-2H-5-tetrazo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Turin Curated by ChEMBL | Assay Description Displacement of (RS)-[3H]AMPA from recombinant rat GluA4 expressed in baculovirus infected Sf9 insect cell membranes | J Med Chem 62: 4467-4482 (2019) Article DOI: 10.1021/acs.jmedchem.8b01986 BindingDB Entry DOI: 10.7270/Q2NG4V06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Rattus norvegicus) | BDBM17657 ((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Torino Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from rat iGluR2 receptor expressed in Sf9 cells baculovirus system after 1 to 2 hrs by liquid scintillation counting | J Med Chem 53: 4110-8 (2010) Article DOI: 10.1021/jm1001452 BindingDB Entry DOI: 10.7270/Q2RR206G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2D (Rattus norvegicus (Rat)) | BDBM213888 (1-thioxo-1,2-dihydro-[1,2,4]triazolo[4,3-a]-quinox...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | Article PubMed | >300 | >-37.2 | >3.00E+3 | n/a | n/a | n/a | n/a | 7.4 | 25 |
University of Copenhagen | Assay Description Two-electrode voltage clamp (TEVC) recordings were performed on Xenopus oocytes at room temperature 3-6 days postinjection using an OC-725C TEVC ampl... | J Biol Chem 288: 33124-35 (2013) Article DOI: 10.1074/jbc.M113.480210 BindingDB Entry DOI: 10.7270/Q2MG7NB1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Rattus norvegicus) | BDBM50512944 (CHEMBL4529665) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB Article PubMed | 320 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Turin Curated by ChEMBL | Assay Description Displacement of (RS)-[3H]AMPA from recombinant rat GluA2-ABD expressed in baculovirus infected Sf9 insect cell membranes | J Med Chem 62: 4467-4482 (2019) Article DOI: 10.1021/acs.jmedchem.8b01986 BindingDB Entry DOI: 10.7270/Q2NG4V06 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor ionotropic, kainate 2 (Rattus norvegicus) | BDBM17657 ((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 330 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Torino Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from rat iGluR6 receptor expressed in Sf9 cells baculovirus system after 1 to 2 hrs by liquid scintillation counting | J Med Chem 53: 4110-8 (2010) Article DOI: 10.1021/jm1001452 BindingDB Entry DOI: 10.7270/Q2RR206G | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Glutamate receptor 3 (RAT) | BDBM50211399 ((RS)-2-amino-3-[3-hydroxy-5-(2-benzyl-2H-5-tetrazo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 390 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Turin Curated by ChEMBL | Assay Description Displacement of (RS)-[3H]AMPA from recombinant rat GluA3 expressed in baculovirus infected Sf9 insect cell membranes | J Med Chem 62: 4467-4482 (2019) Article DOI: 10.1021/acs.jmedchem.8b01986 BindingDB Entry DOI: 10.7270/Q2NG4V06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1/2A (Rattus norvegicus (Rat)-RAT) | BDBM81977 (CAS_79055-68-8 | CB3371309 | D-AP5 | D-APV) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 390 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Eastern Finland Curated by ChEMBL | Assay Description Antagonist activity at recombinant rat GluN1a/GluN2A expressed in Xenopus laevis oocytes assessed as inhibition of glycine/glutamate-mediated current... | J Med Chem 60: 9885-9904 (2017) Article DOI: 10.1021/acs.jmedchem.7b01624 BindingDB Entry DOI: 10.7270/Q21R6SXD | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM17657 ((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 490 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Torino Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from rat iGluR7 receptor expressed in Sf9 cells baculovirus system after 1 to 2 hrs by liquid scintillation counting | J Med Chem 53: 4110-8 (2010) Article DOI: 10.1021/jm1001452 BindingDB Entry DOI: 10.7270/Q2RR206G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2A (Rattus norvegicus (Rat)) | BDBM213888 (1-thioxo-1,2-dihydro-[1,2,4]triazolo[4,3-a]-quinox...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | Article PubMed | 560 | -35.7 | 770 | n/a | n/a | n/a | n/a | 7.4 | 25 |
University of Copenhagen | Assay Description Two-electrode voltage clamp (TEVC) recordings were performed on Xenopus oocytes at room temperature 3-6 days postinjection using an OC-725C TEVC ampl... | J Biol Chem 288: 33124-35 (2013) Article DOI: 10.1074/jbc.M113.480210 BindingDB Entry DOI: 10.7270/Q2MG7NB1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Rattus norvegicus) | BDBM50512944 (CHEMBL4529665) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB Article PubMed | 710 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Turin Curated by ChEMBL | Assay Description Displacement of (RS)-[3H]AMPA from recombinant rat GluA2(R) expressed in baculovirus infected Sf9 insect cell membranes | J Med Chem 62: 4467-4482 (2019) Article DOI: 10.1021/acs.jmedchem.8b01986 BindingDB Entry DOI: 10.7270/Q2NG4V06 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor 2 (Rattus norvegicus) | BDBM50211399 ((RS)-2-amino-3-[3-hydroxy-5-(2-benzyl-2H-5-tetrazo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 750 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Turin Curated by ChEMBL | Assay Description Displacement of (RS)-[3H]AMPA from recombinant rat GluA2(R) expressed in baculovirus infected Sf9 insect cell membranes | J Med Chem 62: 4467-4482 (2019) Article DOI: 10.1021/acs.jmedchem.8b01986 BindingDB Entry DOI: 10.7270/Q2NG4V06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat)) | BDBM213888 (1-thioxo-1,2-dihydro-[1,2,4]triazolo[4,3-a]-quinox...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | Article PubMed | >800 | >-34.8 | >3.00E+3 | n/a | n/a | n/a | n/a | 7.4 | 25 |
University of Copenhagen | Assay Description Two-electrode voltage clamp (TEVC) recordings were performed on Xenopus oocytes at room temperature 3-6 days postinjection using an OC-725C TEVC ampl... | J Biol Chem 288: 33124-35 (2013) Article DOI: 10.1074/jbc.M113.480210 BindingDB Entry DOI: 10.7270/Q2MG7NB1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat)) | BDBM213888 (1-thioxo-1,2-dihydro-[1,2,4]triazolo[4,3-a]-quinox...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | Article PubMed | >1.30E+3 | >-33.6 | >3.00E+3 | n/a | n/a | n/a | n/a | 7.4 | 25 |
University of Copenhagen | Assay Description Two-electrode voltage clamp (TEVC) recordings were performed on Xenopus oocytes at room temperature 3-6 days postinjection using an OC-725C TEVC ampl... | J Biol Chem 288: 33124-35 (2013) Article DOI: 10.1074/jbc.M113.480210 BindingDB Entry DOI: 10.7270/Q2MG7NB1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Rattus norvegicus) | BDBM50512939 (CHEMBL3742451) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.87E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Turin Curated by ChEMBL | Assay Description Displacement of (RS)-[3H]AMPA from recombinant rat GluA2(R) expressed in baculovirus infected Sf9 insect cell membranes | J Med Chem 62: 4467-4482 (2019) Article DOI: 10.1021/acs.jmedchem.8b01986 BindingDB Entry DOI: 10.7270/Q2NG4V06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 3 (RAT) | BDBM50512944 (CHEMBL4529665) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB Article PubMed | 1.91E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Turin Curated by ChEMBL | Assay Description Displacement of (RS)-[3H]AMPA from recombinant rat GluA3 expressed in baculovirus infected Sf9 insect cell membranes | J Med Chem 62: 4467-4482 (2019) Article DOI: 10.1021/acs.jmedchem.8b01986 BindingDB Entry DOI: 10.7270/Q2NG4V06 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor 2 (Rattus norvegicus) | BDBM50512940 (CHEMBL3742450) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB Article PubMed | 1.97E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Turin Curated by ChEMBL | Assay Description Displacement of (RS)-[3H]AMPA from recombinant rat GluA2-ABD expressed in baculovirus infected Sf9 insect cell membranes | J Med Chem 62: 4467-4482 (2019) Article DOI: 10.1021/acs.jmedchem.8b01986 BindingDB Entry DOI: 10.7270/Q2NG4V06 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT) | BDBM81977 (CAS_79055-68-8 | CB3371309 | D-AP5 | D-APV) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Eastern Finland Curated by ChEMBL | Assay Description Antagonist activity at recombinant rat GluN1a/GluN2B expressed in Xenopus laevis oocytes assessed as inhibition of glycine/glutamate-mediated current... | J Med Chem 60: 9885-9904 (2017) Article DOI: 10.1021/acs.jmedchem.7b01624 BindingDB Entry DOI: 10.7270/Q21R6SXD | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor 2 (Rattus norvegicus) | BDBM50512941 (CHEMBL4556711) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Turin Curated by ChEMBL | Assay Description Displacement of (RS)-[3H]AMPA from recombinant rat GluA2(R) expressed in baculovirus infected Sf9 insect cell membranes | J Med Chem 62: 4467-4482 (2019) Article DOI: 10.1021/acs.jmedchem.8b01986 BindingDB Entry DOI: 10.7270/Q2NG4V06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 4 (Rattus norvegicus) | BDBM50512939 (CHEMBL3742451) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 4.08E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Turin Curated by ChEMBL | Assay Description Displacement of (RS)-[3H]AMPA from recombinant rat GluA4 expressed in baculovirus infected Sf9 insect cell membranes | J Med Chem 62: 4467-4482 (2019) Article DOI: 10.1021/acs.jmedchem.8b01986 BindingDB Entry DOI: 10.7270/Q2NG4V06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Rattus norvegicus) | BDBM50512940 (CHEMBL3742450) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB Article PubMed | 4.38E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Turin Curated by ChEMBL | Assay Description Displacement of (RS)-[3H]AMPA from recombinant rat GluA2(R) expressed in baculovirus infected Sf9 insect cell membranes | J Med Chem 62: 4467-4482 (2019) Article DOI: 10.1021/acs.jmedchem.8b01986 BindingDB Entry DOI: 10.7270/Q2NG4V06 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor ionotropic, NMDA 1/2A (Rattus norvegicus (Rat)-RAT) | BDBM50246910 (CHEMBL4084540) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 4.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Eastern Finland Curated by ChEMBL | Assay Description Antagonist activity at recombinant rat GluN1a/GluN2A expressed in Xenopus laevis oocytes assessed as inhibition of glycine/glutamate-mediated current... | J Med Chem 60: 9885-9904 (2017) Article DOI: 10.1021/acs.jmedchem.7b01624 BindingDB Entry DOI: 10.7270/Q21R6SXD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 3 (RAT) | BDBM50512940 (CHEMBL3742450) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB Article PubMed | 4.89E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Turin Curated by ChEMBL | Assay Description Displacement of (RS)-[3H]AMPA from recombinant rat GluA3 expressed in baculovirus infected Sf9 insect cell membranes | J Med Chem 62: 4467-4482 (2019) Article DOI: 10.1021/acs.jmedchem.8b01986 BindingDB Entry DOI: 10.7270/Q2NG4V06 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor 3 (RAT) | BDBM50512939 (CHEMBL3742451) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 4.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Turin Curated by ChEMBL | Assay Description Displacement of (RS)-[3H]AMPA from recombinant rat GluA3 expressed in baculovirus infected Sf9 insect cell membranes | J Med Chem 62: 4467-4482 (2019) Article DOI: 10.1021/acs.jmedchem.8b01986 BindingDB Entry DOI: 10.7270/Q2NG4V06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat)) | BDBM81977 (CAS_79055-68-8 | CB3371309 | D-AP5 | D-APV) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 5.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Eastern Finland Curated by ChEMBL | Assay Description Antagonist activity at recombinant rat GluN1a/GluN2C expressed in Xenopus laevis oocytes assessed as inhibition of glycine/glutamate-mediated current... | J Med Chem 60: 9885-9904 (2017) Article DOI: 10.1021/acs.jmedchem.7b01624 BindingDB Entry DOI: 10.7270/Q21R6SXD | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor 1 (Rattus norvegicus (Rat)) | BDBM50211399 ((RS)-2-amino-3-[3-hydroxy-5-(2-benzyl-2H-5-tetrazo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Turin Curated by ChEMBL | Assay Description Displacement of (RS)-[3H]AMPA from recombinant rat GluA1 expressed in baculovirus infected Sf9 insect cell membranes | J Med Chem 62: 4467-4482 (2019) Article DOI: 10.1021/acs.jmedchem.8b01986 BindingDB Entry DOI: 10.7270/Q2NG4V06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 1 (RAT) | BDBM50318264 ((+)-2-Amino-3-(4-hydroxy-1,2,5-oxadiazol-3-yl)prop...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 8.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Torino Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from rat iGluR5 receptor expressed in Sf9 cells baculovirus system after 1 to 2 hrs by liquid scintillation counting | J Med Chem 53: 4110-8 (2010) Article DOI: 10.1021/jm1001452 BindingDB Entry DOI: 10.7270/Q2RR206G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 1 (RAT) | BDBM50318264 ((+)-2-Amino-3-(4-hydroxy-1,2,5-oxadiazol-3-yl)prop...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 8.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Torino Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from rat iGluR5 receptor expressed in Sf9 cells baculovirus system after 1 to 2 hrs by liquid scintillation counting | J Med Chem 53: 4110-8 (2010) Article DOI: 10.1021/jm1001452 BindingDB Entry DOI: 10.7270/Q2RR206G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 1 (Rattus norvegicus (Rat)) | BDBM50512944 (CHEMBL4529665) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid PDB UniChem | Article PubMed | 9.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Turin Curated by ChEMBL | Assay Description Displacement of (RS)-[3H]AMPA from recombinant rat GluA1 expressed in baculovirus infected Sf9 insect cell membranes | J Med Chem 62: 4467-4482 (2019) Article DOI: 10.1021/acs.jmedchem.8b01986 BindingDB Entry DOI: 10.7270/Q2NG4V06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 4 (Rattus norvegicus) | BDBM50512944 (CHEMBL4529665) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB Article PubMed | 9.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Turin Curated by ChEMBL | Assay Description Displacement of (RS)-[3H]AMPA from recombinant rat GluA4 expressed in baculovirus infected Sf9 insect cell membranes | J Med Chem 62: 4467-4482 (2019) Article DOI: 10.1021/acs.jmedchem.8b01986 BindingDB Entry DOI: 10.7270/Q2NG4V06 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT) | BDBM50246910 (CHEMBL4084540) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Eastern Finland Curated by ChEMBL | Assay Description Antagonist activity at recombinant rat GluN1a/GluN2B expressed in Xenopus laevis oocytes assessed as inhibition of glycine/glutamate-mediated current... | J Med Chem 60: 9885-9904 (2017) Article DOI: 10.1021/acs.jmedchem.7b01624 BindingDB Entry DOI: 10.7270/Q21R6SXD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50246919 (CHEMBL4099104) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Eastern Finland Curated by ChEMBL | Assay Description Displacement of [3H]-KA from recombinant homomeric rat GluK3a receptor expressed in baculovirus infected Sf9 insect cell membranes by scintillation c... | J Med Chem 60: 9885-9904 (2017) Article DOI: 10.1021/acs.jmedchem.7b01624 BindingDB Entry DOI: 10.7270/Q21R6SXD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 4 (Rattus norvegicus) | BDBM50512940 (CHEMBL3742450) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB Article PubMed | 1.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Turin Curated by ChEMBL | Assay Description Displacement of (RS)-[3H]AMPA from recombinant rat GluA4 expressed in baculovirus infected Sf9 insect cell membranes | J Med Chem 62: 4467-4482 (2019) Article DOI: 10.1021/acs.jmedchem.8b01986 BindingDB Entry DOI: 10.7270/Q2NG4V06 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor 3 (RAT) | BDBM50512941 (CHEMBL4556711) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.19E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Turin Curated by ChEMBL | Assay Description Displacement of (RS)-[3H]AMPA from recombinant rat GluA3 expressed in baculovirus infected Sf9 insect cell membranes | J Med Chem 62: 4467-4482 (2019) Article DOI: 10.1021/acs.jmedchem.8b01986 BindingDB Entry DOI: 10.7270/Q2NG4V06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 1 (RAT) | BDBM50246919 (CHEMBL4099104) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Eastern Finland Curated by ChEMBL | Assay Description Displacement of [3H]-SYM2081 from recombinant homomeric rat GluK1 (Q)1b receptor expressed in baculovirus infected Sf9 insect cell membranes by scint... | J Med Chem 60: 9885-9904 (2017) Article DOI: 10.1021/acs.jmedchem.7b01624 BindingDB Entry DOI: 10.7270/Q21R6SXD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 1 (Rattus norvegicus (Rat)) | BDBM50512939 (CHEMBL3742451) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.57E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Turin Curated by ChEMBL | Assay Description Displacement of (RS)-[3H]AMPA from recombinant rat GluA1 expressed in baculovirus infected Sf9 insect cell membranes | J Med Chem 62: 4467-4482 (2019) Article DOI: 10.1021/acs.jmedchem.8b01986 BindingDB Entry DOI: 10.7270/Q2NG4V06 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 2 (Rattus norvegicus) | BDBM50318266 ((+)-2-Amino-5-(4-hydroxy-1,2,5-oxadiazol-3-yl)pent...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Torino Curated by ChEMBL | Assay Description Displacement of [3H]AMPA from rat iGluR2 receptor expressed in Sf9 cells baculovirus system after 1 to 2 hrs by liquid scintillation counting | J Med Chem 53: 4110-8 (2010) Article DOI: 10.1021/jm1001452 BindingDB Entry DOI: 10.7270/Q2RR206G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1/2D (RAT-Rattus norvegicus (Rat)) | BDBM81977 (CAS_79055-68-8 | CB3371309 | D-AP5 | D-APV) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Eastern Finland Curated by ChEMBL | Assay Description Antagonist activity at recombinant rat GluN1a/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of glycine/glutamate-mediated current... | J Med Chem 60: 9885-9904 (2017) Article DOI: 10.1021/acs.jmedchem.7b01624 BindingDB Entry DOI: 10.7270/Q21R6SXD | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor ionotropic, NMDA 1/2C (RAT-Rattus norvegicus (Rat)) | BDBM50246910 (CHEMBL4084540) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 2.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Eastern Finland Curated by ChEMBL | Assay Description Antagonist activity at recombinant rat GluN1a/GluN2C expressed in Xenopus laevis oocytes assessed as inhibition of glycine/glutamate-mediated current... | J Med Chem 60: 9885-9904 (2017) Article DOI: 10.1021/acs.jmedchem.7b01624 BindingDB Entry DOI: 10.7270/Q21R6SXD | |||||||||||
More data for this Ligand-Target Pair |
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