Found 11 hits with Last Name = 'jang' and Initial = 'hj' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Signal transducer and activator of transcription 3
(Homo sapiens (Human)) | BDBM50090474
(CHEMBL3581710)Show SMILES [H][C@@]1(CC[C@]2(C)[C@]1([H])[C@H](O)C[C@]1([H])[C@@]3(C)C[C@@H](O)[C@H](O)C(C)(C)[C@]3([H])CC[C@@]21C)[C@](C)(CCC(=O)C(C)=C)O[C@@H]1O[C@H](CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C22H25NO6S/c1-13-10-16(23-21(25)22(26)27)11-14(2)20(13)30(28,29)17-8-9-19(24)18(12-17)15-6-4-3-5-7-15/h8-12,15,24H,3-7H2,1-2H3,(H,23,25)(H,26,27) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
Chungbuk National University
Curated by ChEMBL
| Assay Description Inhibition of IL6-induced STAT3 activation in human Hep3B cells after 12 hrs by luciferase assay |
J Nat Prod 78: 971-6 (2015)
Article DOI: 10.1021/np500803e BindingDB Entry DOI: 10.7270/Q22B90SD |
More data for this Ligand-Target Pair | |
Signal transducer and activator of transcription 3
(Homo sapiens (Human)) | BDBM50090504
(CHEMBL3581714)Show SMILES [H][C@@]1(CC[C@]2(C)[C@]1([H])[C@H](O)C[C@]1([H])[C@@]3(C)C[C@@H](O)[C@H](O)C(C)(C)[C@]3([H])CC[C@@]21C)[C@](C)(C\C=C\C(C)C)O[C@@H]1O[C@H](CO[C@@H]2O[C@@H](C)[C@H](O)[C@@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C19H29O9P.Na/c1-19(23,12-11-16-9-7-10-18(22)27-16)17(28-29(24,25)26)14-15(21)8-5-3-2-4-6-13-20;/h2-4,6-7,10-12,15-17,20-21,23H,5,8-9,13-14H2,1H3,(H2,24,25,26);/q;+1/p-1/b3-2-,6-4+,12-11+;/t15-,16+,17+,19+;/m0./s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Chungbuk National University
Curated by ChEMBL
| Assay Description Inhibition of IL6-induced STAT3 activation in human Hep3B cells after 12 hrs by luciferase assay |
J Nat Prod 78: 971-6 (2015)
Article DOI: 10.1021/np500803e BindingDB Entry DOI: 10.7270/Q22B90SD |
More data for this Ligand-Target Pair | |
Signal transducer and activator of transcription 3
(Homo sapiens (Human)) | BDBM50090483
(CHEMBL3581712)Show SMILES [H][C@@]1(CC[C@]2(C)[C@]1([H])[C@H](O)C[C@]1([H])[C@@]3(C)C[C@@H](O)[C@H](O)C(C)(C)[C@]3([H])CC[C@@]21C)[C@](C)(CCC(=O)C(C)=C)O[C@@H]1O[C@H](CO[C@@H]2O[C@@H](C)[C@H](O)[C@@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C34H38Cl2N2O6S/c1-41-29-18-24(19-30(42-2)31(29)43-3)32(39)38-16-17-44-33(22-38,25-8-9-27(35)28(36)20-25)10-13-37-14-11-34(12-15-37)26-7-5-4-6-23(26)21-45(34)40/h4-9,18-20H,10-17,21-22H2,1-3H3/t33-,45?/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 590 | n/a | n/a | n/a | n/a | n/a | n/a |
Chungbuk National University
Curated by ChEMBL
| Assay Description Inhibition of IL6-induced STAT3 activation in human Hep3B cells after 12 hrs by luciferase assay |
J Nat Prod 78: 971-6 (2015)
Article DOI: 10.1021/np500803e BindingDB Entry DOI: 10.7270/Q22B90SD |
More data for this Ligand-Target Pair | |
Signal transducer and activator of transcription 3
(Homo sapiens (Human)) | BDBM50090486
(CHEMBL3581713)Show SMILES [H][C@@]1(CC[C@]2(C)[C@]1([H])[C@H](O)C[C@]1([H])[C@@]3(C)CC[C@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C(C)(C)[C@]3([H])CC[C@@]21C)[C@](C)(C\C=C\C(C)C)O[C@@H]1O[C@H](CO[C@@H]2O[C@@H](C)[C@H](O)[C@@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C34H38Cl2N2O6S/c1-41-29-18-24(19-30(42-2)31(29)43-3)32(39)38-16-17-44-33(22-38,25-8-9-27(35)28(36)20-25)10-13-37-14-11-34(12-15-37)26-7-5-4-6-23(26)21-45(34)40/h4-9,18-20H,10-17,21-22H2,1-3H3/t33-,45?/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chungbuk National University
Curated by ChEMBL
| Assay Description Inhibition of IL6-induced STAT3 activation in human Hep3B cells after 12 hrs by luciferase assay |
J Nat Prod 78: 971-6 (2015)
Article DOI: 10.1021/np500803e BindingDB Entry DOI: 10.7270/Q22B90SD |
More data for this Ligand-Target Pair | |
Signal transducer and activator of transcription 3
(Homo sapiens (Human)) | BDBM50090480
(CHEMBL3581705)Show SMILES [H][C@@]1(CC[C@]2(C)[C@]1([H])[C@H](O)C[C@]1([H])[C@@]3(C)C[C@@H](O)[C@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C(C)(C)[C@]3([H])CC[C@@]21C)[C@](C)(C\C=C\C(C)(C)O)O[C@@H]1O[C@H](CO[C@@H]2O[C@@H](C)[C@H](O)[C@@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C17H17NO5/c1-9-8-13(4-5-14(9)19)23-15-10(2)6-12(7-11(15)3)18-16(20)17(21)22/h4-8,19H,1-3H3,(H,18,20)(H,21,22) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.71E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chungbuk National University
Curated by ChEMBL
| Assay Description Inhibition of IL6-induced STAT3 activation in human Hep3B cells after 12 hrs by luciferase assay |
J Nat Prod 78: 971-6 (2015)
Article DOI: 10.1021/np500803e BindingDB Entry DOI: 10.7270/Q22B90SD |
More data for this Ligand-Target Pair | |
Signal transducer and activator of transcription 3
(Homo sapiens (Human)) | BDBM50090481
(CHEMBL3581711)Show SMILES [H][C@@]1(CC[C@]2(C)[C@]1([H])[C@H](O)C[C@]1([H])[C@@]3(C)C[C@@H](O)[C@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C(C)(C)[C@]3([H])CC[C@@]21C)[C@](C)(C\C=C\C(C)C)O[C@@H]1O[C@H](CO[C@@H]2O[C@@H](C)[C@H](O)[C@@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C22H18FNO5/c1-12-8-16(24-21(26)22(27)28)9-13(2)20(12)29-17-6-7-19(25)18(11-17)14-4-3-5-15(23)10-14/h3-11,25H,1-2H3,(H,24,26)(H,27,28) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.76E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chungbuk National University
Curated by ChEMBL
| Assay Description Inhibition of IL6-induced STAT3 activation in human Hep3B cells after 12 hrs by luciferase assay |
J Nat Prod 78: 971-6 (2015)
Article DOI: 10.1021/np500803e BindingDB Entry DOI: 10.7270/Q22B90SD |
More data for this Ligand-Target Pair | |
Signal transducer and activator of transcription 3
(Homo sapiens (Human)) | BDBM50090475
(CHEMBL3581709)Show SMILES [H][C@@]1(CC[C@]2(C)[C@]1([H])[C@H](O)C[C@]1([H])[C@@]3(C)C[C@@H](O)[C@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C(C)(C)[C@]3([H])CC[C@@]21C)[C@](C)(CCC(=O)C(C)=C)O[C@@H]1O[C@H](CO[C@@H]2O[C@@H](C)[C@H](O)[C@@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C22H19NO5/c1-13-10-16(23-21(25)22(26)27)11-14(2)20(13)28-17-8-9-19(24)18(12-17)15-6-4-3-5-7-15/h3-12,24H,1-2H3,(H,23,25)(H,26,27) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.92E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chungbuk National University
Curated by ChEMBL
| Assay Description Inhibition of IL6-induced STAT3 activation in human Hep3B cells after 12 hrs by luciferase assay |
J Nat Prod 78: 971-6 (2015)
Article DOI: 10.1021/np500803e BindingDB Entry DOI: 10.7270/Q22B90SD |
More data for this Ligand-Target Pair | |
Signal transducer and activator of transcription 3
(Homo sapiens (Human)) | BDBM50090478
(CHEMBL3581706)Show SMILES [H][C@@]1(CC[C@]2(C)[C@]1([H])[C@H](O)C[C@]1([H])[C@@]3(C)C[C@@H](O)[C@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C(C)(C)[C@]3([H])CC[C@@]21C)[C@](C)(C\C=C\C(C)(C)OO)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C23H18F3NO5/c1-12-8-16(27-21(29)22(30)31)9-13(2)20(12)32-17-6-7-19(28)18(11-17)14-4-3-5-15(10-14)23(24,25)26/h3-11,28H,1-2H3,(H,27,29)(H,30,31) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chungbuk National University
Curated by ChEMBL
| Assay Description Inhibition of IL6-induced STAT3 activation in human Hep3B cells after 12 hrs by luciferase assay |
J Nat Prod 78: 971-6 (2015)
Article DOI: 10.1021/np500803e BindingDB Entry DOI: 10.7270/Q22B90SD |
More data for this Ligand-Target Pair | |
Signal transducer and activator of transcription 3
(Homo sapiens (Human)) | BDBM50090477
(CHEMBL3581707)Show SMILES [H][C@@]1(CC[C@]2(C)[C@]1([H])[C@H](O)C[C@]1([H])[C@@]3(C)C[C@@H](O)[C@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C(C)(C)[C@]3([H])CC[C@@]21C)[C@](C)(C\C=C\C(C)(C)OO)O[C@@H]1O[C@H](CO[C@@H]2O[C@@H](C)[C@H](O)[C@@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C22H18ClNO5/c1-12-8-16(24-21(26)22(27)28)9-13(2)20(12)29-17-6-7-19(25)18(11-17)14-4-3-5-15(23)10-14/h3-11,25H,1-2H3,(H,24,26)(H,27,28) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chungbuk National University
Curated by ChEMBL
| Assay Description Inhibition of IL6-induced STAT3 activation in human Hep3B cells after 12 hrs by luciferase assay |
J Nat Prod 78: 971-6 (2015)
Article DOI: 10.1021/np500803e BindingDB Entry DOI: 10.7270/Q22B90SD |
More data for this Ligand-Target Pair | |
Signal transducer and activator of transcription 3
(Homo sapiens (Human)) | BDBM50090476
(CHEMBL3581708)Show SMILES [H][C@@]1(CC[C@]2(C)[C@]1([H])[C@H](O)C[C@]1([H])[C@@]3(C)C[C@@H](O)[C@H](O)C(C)(C)[C@]3([H])CC[C@@]21C)[C@](C)(C\C=C\C(C)(C)OO)O[C@@H]1O[C@H](CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C22H25NO4S/c1-13-10-16(23-21(25)22(26)27)11-14(2)20(13)28-17-8-9-19(24)18(12-17)15-6-4-3-5-7-15/h8-12,15,24H,3-7H2,1-2H3,(H,23,25)(H,26,27) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chungbuk National University
Curated by ChEMBL
| Assay Description Inhibition of IL6-induced STAT3 activation in human Hep3B cells after 12 hrs by luciferase assay |
J Nat Prod 78: 971-6 (2015)
Article DOI: 10.1021/np500803e BindingDB Entry DOI: 10.7270/Q22B90SD |
More data for this Ligand-Target Pair | |
Signal transducer and activator of transcription 3
(Homo sapiens (Human)) | BDBM50090479
(CHEMBL3581704)Show SMILES [H][C@@]1(CC[C@]2(C)[C@]1([H])[C@H](O)C[C@]1([H])[C@@]3(C)C[C@@H](O)[C@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C(C)(C)[C@]3([H])CC[C@@]21C)[C@](C)(C\C=C\C(C)C)O[C@@H]1O[C@H](CO[C@@H]2O[C@@H](C)[C@H](O)[C@@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C22H18ClNO5/c1-12-9-14(24-21(26)22(27)28)10-13(2)20(12)29-15-7-8-19(25)17(11-15)16-5-3-4-6-18(16)23/h3-11,25H,1-2H3,(H,24,26)(H,27,28) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chungbuk National University
Curated by ChEMBL
| Assay Description Inhibition of IL6-induced STAT3 activation in human Hep3B cells after 12 hrs by luciferase assay |
J Nat Prod 78: 971-6 (2015)
Article DOI: 10.1021/np500803e BindingDB Entry DOI: 10.7270/Q22B90SD |
More data for this Ligand-Target Pair | |