Compile Data Set for Download or QSAR

Found 626 hits with Last Name = 'kern' and Initial = 'c'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50319772 ((2'-methylbiphenyl-4-yl)((1S,5R)-1,3,3-trimethyl-6...) Show SMILES Cc1ccccc1-c1ccc(cc1)C(=O)N1C[C@]2(C)C[C@H]1CC(C)(C)C2 |r| Show InChI InChI=1S/C24H29NO/c1-17-7-5-6-8-21(17)18-9-11-19(12-10-18)22(26)25-16-24(4)14-20(25)13-23(2,3)15-24/h5-12,20H,13-16H2,1-4H3/t20-,24-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement [3H]Arg human recombinant Vasopressin V1a receptor				Bioorg Med Chem Lett 20: 3742-5 (2010) Article DOI: 10.1016/j.bmcl.2010.04.068 BindingDB Entry DOI: 10.7270/Q24F1QW2
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50319776 ((2,2'-dimethylbiphenyl-4-yl)((1S,5R)-1,3,3-trimeth...) Show SMILES Cc1ccccc1-c1ccc(cc1C)C(=O)N1C[C@]2(C)C[C@H]1CC(C)(C)C2 |r| Show InChI InChI=1S/C25H31NO/c1-17-8-6-7-9-21(17)22-11-10-19(12-18(22)2)23(27)26-16-25(5)14-20(26)13-24(3,4)15-25/h6-12,20H,13-16H2,1-5H3/t20-,25-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement [3H]Arg human recombinant Vasopressin V1a receptor				Bioorg Med Chem Lett 20: 3742-5 (2010) Article DOI: 10.1016/j.bmcl.2010.04.068 BindingDB Entry DOI: 10.7270/Q24F1QW2
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50319799 ((4-(1H-indol-3-yl)-3-methoxyphenyl)((1S,5R)-1,3,3-...) Show SMILES COc1cc(ccc1-c1c[nH]c2ccccc12)C(=O)N1C[C@]2(C)C[C@H]1CC(C)(C)C2 |r| Show InChI InChI=1S/C26H30N2O2/c1-25(2)12-18-13-26(3,15-25)16-28(18)24(29)17-9-10-20(23(11-17)30-4)21-14-27-22-8-6-5-7-19(21)22/h5-11,14,18,27H,12-13,15-16H2,1-4H3/t18-,26-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement [3H]Arg human recombinant Vasopressin V1a receptor				Bioorg Med Chem Lett 20: 3742-5 (2010) Article DOI: 10.1016/j.bmcl.2010.04.068 BindingDB Entry DOI: 10.7270/Q24F1QW2
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50319774 ((3-chloro-2'-methylbiphenyl-4-yl)((1S,5R)-1,3,3-tr...) Show SMILES Cc1ccccc1-c1ccc(C(=O)N2C[C@]3(C)C[C@H]2CC(C)(C)C3)c(Cl)c1 |r| Show InChI InChI=1S/C24H28ClNO/c1-16-7-5-6-8-19(16)17-9-10-20(21(25)11-17)22(27)26-15-24(4)13-18(26)12-23(2,3)14-24/h5-11,18H,12-15H2,1-4H3/t18-,24-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement [3H]Arg human recombinant Vasopressin V1a receptor				Bioorg Med Chem Lett 20: 3742-5 (2010) Article DOI: 10.1016/j.bmcl.2010.04.068 BindingDB Entry DOI: 10.7270/Q24F1QW2
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM85095 (CAS_151171 | CONIVAPTAN | NSC_151171 | YM087) Show SMILES Cc1nc-2c(CCN(C(=O)c3ccc(NC(=O)c4ccccc4-c4ccccc4)cc3)c3ccccc-23)[nH]1 Show InChI InChI=1S/C32H26N4O2/c1-21-33-28-19-20-36(29-14-8-7-13-27(29)30(28)34-21)32(38)23-15-17-24(18-16-23)35-31(37)26-12-6-5-11-25(26)22-9-3-2-4-10-22/h2-18H,19-20H2,1H3,(H,33,34)(H,35,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	0.360	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement [3H]Arg human recombinant Vasopressin V2 receptor				Bioorg Med Chem Lett 20: 3742-5 (2010) Article DOI: 10.1016/j.bmcl.2010.04.068 BindingDB Entry DOI: 10.7270/Q24F1QW2
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50319788 (CHEMBL1084325 | N-(2'-methoxy-4'-((1S,5R)-1,3,3-tr...) Show SMILES COc1cc(ccc1-c1cccc(NC(C)=O)c1)C(=O)N1C[C@]2(C)C[C@H]1CC(C)(C)C2 |r| Show InChI InChI=1S/C26H32N2O3/c1-17(29)27-20-8-6-7-18(11-20)22-10-9-19(12-23(22)31-5)24(30)28-16-26(4)14-21(28)13-25(2,3)15-26/h6-12,21H,13-16H2,1-5H3,(H,27,29)/t21-,26-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement [3H]Arg human recombinant Vasopressin V1a receptor				Bioorg Med Chem Lett 20: 3742-5 (2010) Article DOI: 10.1016/j.bmcl.2010.04.068 BindingDB Entry DOI: 10.7270/Q24F1QW2
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM85095 (CAS_151171 | CONIVAPTAN | NSC_151171 | YM087) Show SMILES Cc1nc-2c(CCN(C(=O)c3ccc(NC(=O)c4ccccc4-c4ccccc4)cc3)c3ccccc-23)[nH]1 Show InChI InChI=1S/C32H26N4O2/c1-21-33-28-19-20-36(29-14-8-7-13-27(29)30(28)34-21)32(38)23-15-17-24(18-16-23)35-31(37)26-12-6-5-11-25(26)22-9-3-2-4-10-22/h2-18H,19-20H2,1H3,(H,33,34)(H,35,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	0.430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement [3H]Arg human recombinant Vasopressin V1a receptor				Bioorg Med Chem Lett 20: 3742-5 (2010) Article DOI: 10.1016/j.bmcl.2010.04.068 BindingDB Entry DOI: 10.7270/Q24F1QW2
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50319780 ((2-chloro-5-methoxy-2'-methylbiphenyl-4-yl)((1S,5R...) Show SMILES COc1cc(c(Cl)cc1C(=O)N1C[C@]2(C)C[C@H]1CC(C)(C)C2)-c1ccccc1C |r| Show InChI InChI=1S/C25H30ClNO2/c1-16-8-6-7-9-18(16)19-11-22(29-5)20(10-21(19)26)23(28)27-15-25(4)13-17(27)12-24(2,3)14-25/h6-11,17H,12-15H2,1-5H3/t17-,25-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.540	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement [3H]Arg human recombinant Vasopressin V1a receptor				Bioorg Med Chem Lett 20: 3742-5 (2010) Article DOI: 10.1016/j.bmcl.2010.04.068 BindingDB Entry DOI: 10.7270/Q24F1QW2
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50319782 ((2-methoxy-2',6'-dimethylbiphenyl-4-yl)((1S,5R)-1,...) Show SMILES COc1cc(ccc1-c1c(C)cccc1C)C(=O)N1C[C@]2(C)C[C@H]1CC(C)(C)C2 |r,wU:23.24,20.22,(7.58,-29.96,;8.94,-30.72,;10.28,-29.93,;10.27,-28.4,;11.6,-27.62,;12.94,-28.38,;12.94,-29.92,;11.61,-30.69,;11.62,-32.23,;10.29,-33,;8.96,-32.23,;10.29,-34.55,;11.62,-35.32,;12.96,-34.54,;12.95,-32.99,;14.29,-32.21,;11.59,-26.08,;10.26,-25.31,;12.92,-25.3,;13.87,-26.51,;15.41,-26.52,;16.03,-27.93,;14.61,-24.55,;13.28,-23.79,;14.67,-23.14,;16.05,-23.83,;16.45,-22.33,;17.54,-23.42,;16.39,-25.33,)| Show InChI InChI=1S/C26H33NO2/c1-17-8-7-9-18(2)23(17)21-11-10-19(12-22(21)29-6)24(28)27-16-26(5)14-20(27)13-25(3,4)15-26/h7-12,20H,13-16H2,1-6H3/t20-,26-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement [3H]Arg human recombinant Vasopressin V1a receptor				Bioorg Med Chem Lett 20: 3742-5 (2010) Article DOI: 10.1016/j.bmcl.2010.04.068 BindingDB Entry DOI: 10.7270/Q24F1QW2
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50319806 ((3-methoxy-4-(quinolin-8-yl)phenyl)((1S,5R)-1,3,3-...) Show SMILES COc1cc(ccc1-c1cccc2cccnc12)C(=O)N1C[C@]2(C)C[C@H]1CC(C)(C)C2 |r| Show InChI InChI=1S/C27H30N2O2/c1-26(2)14-20-15-27(3,16-26)17-29(20)25(30)19-10-11-21(23(13-19)31-4)22-9-5-7-18-8-6-12-28-24(18)22/h5-13,20H,14-17H2,1-4H3/t20-,27-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.710	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement [3H]Arg human recombinant Vasopressin V1a receptor				Bioorg Med Chem Lett 20: 3742-5 (2010) Article DOI: 10.1016/j.bmcl.2010.04.068 BindingDB Entry DOI: 10.7270/Q24F1QW2
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50319797 ((4-(benzo[b]thiophen-3-yl)-3-methoxyphenyl)((1S,5R...) Show SMILES COc1cc(ccc1-c1csc2ccccc12)C(=O)N1C[C@]2(C)C[C@H]1CC(C)(C)C2 |r| Show InChI InChI=1S/C26H29NO2S/c1-25(2)12-18-13-26(3,15-25)16-27(18)24(28)17-9-10-19(22(11-17)29-4)21-14-30-23-8-6-5-7-20(21)23/h5-11,14,18H,12-13,15-16H2,1-4H3/t18-,26-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.790	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement [3H]Arg human recombinant Vasopressin V1a receptor				Bioorg Med Chem Lett 20: 3742-5 (2010) Article DOI: 10.1016/j.bmcl.2010.04.068 BindingDB Entry DOI: 10.7270/Q24F1QW2
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50319792 ((2-methoxy-4'-methylbiphenyl-4-yl)((1S,5R)-1,3,3-t...) Show SMILES COc1cc(ccc1-c1ccc(C)cc1)C(=O)N1C[C@]2(C)C[C@H]1CC(C)(C)C2 |r| Show InChI InChI=1S/C25H31NO2/c1-17-6-8-18(9-7-17)21-11-10-19(12-22(21)28-5)23(27)26-16-25(4)14-20(26)13-24(2,3)15-25/h6-12,20H,13-16H2,1-5H3/t20-,25-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement [3H]Arg human recombinant Vasopressin V1a receptor				Bioorg Med Chem Lett 20: 3742-5 (2010) Article DOI: 10.1016/j.bmcl.2010.04.068 BindingDB Entry DOI: 10.7270/Q24F1QW2
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Homo sapiens (Human))	BDBM27960 ((2R,3S)-1-[(7-methyl-2,3-dihydro-1H-inden-4-yl)oxy...) Show SMILES CC(C)N[C@@H](C)[C@@H](O)COc1ccc(C)c2CCCc12 Show InChI InChI=1S/C17H27NO2/c1-11(2)18-13(4)16(19)10-20-17-9-8-12(3)14-6-5-7-15(14)17/h8-9,11,13,16,18-19H,5-7,10H2,1-4H3/t13-,16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1	-50.9	3	n/a	n/a	n/a	n/a	7.4	22
Intervet Innovation GmbH					Assay Description In the binding assays, the results were expressed as percent inhibition of the control radioligand specific binding. The IC50 values (concentration c...				J Med Chem 52: 1773-7 (2009) Article DOI: 10.1021/jm801211c BindingDB Entry DOI: 10.7270/Q2H993HR
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50319787 (2'-methoxy-N-methyl-4'-((1S,5R)-1,3,3-trimethyl-6-...) Show SMILES CNC(=O)c1cccc(c1)-c1ccc(cc1OC)C(=O)N1C[C@]2(C)C[C@H]1CC(C)(C)C2 |r| Show InChI InChI=1S/C26H32N2O3/c1-25(2)13-20-14-26(3,15-25)16-28(20)24(30)19-9-10-21(22(12-19)31-5)17-7-6-8-18(11-17)23(29)27-4/h6-12,20H,13-16H2,1-5H3,(H,27,29)/t20-,26-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.03	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement [3H]Arg human recombinant Vasopressin V1a receptor				Bioorg Med Chem Lett 20: 3742-5 (2010) Article DOI: 10.1016/j.bmcl.2010.04.068 BindingDB Entry DOI: 10.7270/Q24F1QW2
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50319803 ((4-(2-chloro-1,2-pyridin-3-yl)-3-methoxyphenyl)((1...) Show SMILES COc1cc(ccc1-c1cccnc1Cl)C(=O)N1C[C@]2(C)C[C@H]1CC(C)(C)C2 |r| Show InChI InChI=1S/C23H27ClN2O2/c1-22(2)11-16-12-23(3,13-22)14-26(16)21(27)15-7-8-17(19(10-15)28-4)18-6-5-9-25-20(18)24/h5-10,16H,11-14H2,1-4H3/t16-,23-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.07	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement [3H]Arg human recombinant Vasopressin V1a receptor				Bioorg Med Chem Lett 20: 3742-5 (2010) Article DOI: 10.1016/j.bmcl.2010.04.068 BindingDB Entry DOI: 10.7270/Q24F1QW2
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50319791 ((4'-chloro-2-methoxy-2'-methylbiphenyl-4-yl)((1S,5...) Show SMILES COc1cc(ccc1-c1ccc(Cl)cc1C)C(=O)N1C[C@]2(C)C[C@H]1CC(C)(C)C2 |r| Show InChI InChI=1S/C25H30ClNO2/c1-16-10-18(26)7-9-20(16)21-8-6-17(11-22(21)29-5)23(28)27-15-25(4)13-19(27)12-24(2,3)14-25/h6-11,19H,12-15H2,1-5H3/t19-,25-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement [3H]Arg human recombinant Vasopressin V1a receptor				Bioorg Med Chem Lett 20: 3742-5 (2010) Article DOI: 10.1016/j.bmcl.2010.04.068 BindingDB Entry DOI: 10.7270/Q24F1QW2
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50319784 ((2''-Methoxy-[1,1',2',1'']terphenyl-4''-yl)-((1S,5...) Show SMILES COc1cc(ccc1-c1ccccc1-c1ccccc1)C(=O)N1C[C@]2(C)C[C@H]1CC(C)(C)C2 |r| Show InChI InChI=1S/C30H33NO2/c1-29(2)17-23-18-30(3,19-29)20-31(23)28(32)22-14-15-26(27(16-22)33-4)25-13-9-8-12-24(25)21-10-6-5-7-11-21/h5-16,23H,17-20H2,1-4H3/t23-,30-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement [3H]Arg human recombinant Vasopressin V1a receptor				Bioorg Med Chem Lett 20: 3742-5 (2010) Article DOI: 10.1016/j.bmcl.2010.04.068 BindingDB Entry DOI: 10.7270/Q24F1QW2
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50319785 ((5'-chloro-2-methoxy-2'-methylbiphenyl-4-yl)((1S,5...) Show SMILES COc1cc(ccc1-c1cc(Cl)ccc1C)C(=O)N1C[C@]2(C)C[C@H]1CC(C)(C)C2 |r| Show InChI InChI=1S/C25H30ClNO2/c1-16-6-8-18(26)11-21(16)20-9-7-17(10-22(20)29-5)23(28)27-15-25(4)13-19(27)12-24(2,3)14-25/h6-11,19H,12-15H2,1-5H3/t19-,25-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement [3H]Arg human recombinant Vasopressin V1a receptor				Bioorg Med Chem Lett 20: 3742-5 (2010) Article DOI: 10.1016/j.bmcl.2010.04.068 BindingDB Entry DOI: 10.7270/Q24F1QW2
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50334105 ((4-methoxy-3-(phenylethynyl)phenyl)(4-(5-methylpyr...) Show SMILES COc1ccc(cc1C#Cc1ccccc1)C(=O)N1CCN(CC1)c1ccc(C)cn1 Show InChI InChI=1S/C26H25N3O2/c1-20-8-13-25(27-19-20)28-14-16-29(17-15-28)26(30)23-11-12-24(31-2)22(18-23)10-9-21-6-4-3-5-7-21/h3-8,11-13,18-19H,14-17H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-MPEP from rat mGluR5 expressed in HEK293 cells				Bioorg Med Chem Lett 21: 195-9 (2010) Article DOI: 10.1016/j.bmcl.2010.11.038 BindingDB Entry DOI: 10.7270/Q2GQ6Z02
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50319796 ((4-(benzo[b]thiophen-2-yl)-3-methoxyphenyl)((1S,5R...) Show SMILES COc1cc(ccc1-c1cc2ccccc2s1)C(=O)N1C[C@]2(C)C[C@H]1CC(C)(C)C2 |r| Show InChI InChI=1S/C26H29NO2S/c1-25(2)13-19-14-26(3,15-25)16-27(19)24(28)18-9-10-20(21(11-18)29-4)23-12-17-7-5-6-8-22(17)30-23/h5-12,19H,13-16H2,1-4H3/t19-,26-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.78	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement [3H]Arg human recombinant Vasopressin V1a receptor				Bioorg Med Chem Lett 20: 3742-5 (2010) Article DOI: 10.1016/j.bmcl.2010.04.068 BindingDB Entry DOI: 10.7270/Q24F1QW2
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50319794 ((4-(benzofuran-3-yl)-3-methoxyphenyl)((1S,5R)-1,3,...) Show SMILES COc1cc(ccc1-c1coc2ccccc12)C(=O)N1C[C@]2(C)C[C@H]1CC(C)(C)C2 |r| Show InChI InChI=1S/C26H29NO3/c1-25(2)12-18-13-26(3,15-25)16-27(18)24(28)17-9-10-20(23(11-17)29-4)21-14-30-22-8-6-5-7-19(21)22/h5-11,14,18H,12-13,15-16H2,1-4H3/t18-,26-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement [3H]Arg human recombinant Vasopressin V1a receptor				Bioorg Med Chem Lett 20: 3742-5 (2010) Article DOI: 10.1016/j.bmcl.2010.04.068 BindingDB Entry DOI: 10.7270/Q24F1QW2
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50319786 ((2-methoxy-3'-methylbiphenyl-4-yl)((1S,5R)-1,3,3-t...) Show SMILES COc1cc(ccc1-c1cccc(C)c1)C(=O)N1C[C@]2(C)C[C@H]1CC(C)(C)C2 |r| Show InChI InChI=1S/C25H31NO2/c1-17-7-6-8-18(11-17)21-10-9-19(12-22(21)28-5)23(27)26-16-25(4)14-20(26)13-24(2,3)15-25/h6-12,20H,13-16H2,1-5H3/t20-,25-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.97	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement [3H]Arg human recombinant Vasopressin V1a receptor				Bioorg Med Chem Lett 20: 3742-5 (2010) Article DOI: 10.1016/j.bmcl.2010.04.068 BindingDB Entry DOI: 10.7270/Q24F1QW2
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50319790 ((4'-chloro-2-methoxybiphenyl-4-yl)((1S,5R)-1,3,3-t...) Show SMILES COc1cc(ccc1-c1ccc(Cl)cc1)C(=O)N1C[C@]2(C)C[C@H]1CC(C)(C)C2 |r| Show InChI InChI=1S/C24H28ClNO2/c1-23(2)12-19-13-24(3,14-23)15-26(19)22(27)17-7-10-20(21(11-17)28-4)16-5-8-18(25)9-6-16/h5-11,19H,12-15H2,1-4H3/t19-,24-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement [3H]Arg human recombinant Vasopressin V1a receptor				Bioorg Med Chem Lett 20: 3742-5 (2010) Article DOI: 10.1016/j.bmcl.2010.04.068 BindingDB Entry DOI: 10.7270/Q24F1QW2
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50334106 ((3-((3-chlorophenyl)ethynyl)-4-methoxyphenyl)(4-(p...) Show SMILES COc1ccc(cc1C#Cc1cccc(Cl)c1)C(=O)N1CCN(CC1)c1ccncn1 Show InChI InChI=1S/C24H21ClN4O2/c1-31-22-8-7-20(16-19(22)6-5-18-3-2-4-21(25)15-18)24(30)29-13-11-28(12-14-29)23-9-10-26-17-27-23/h2-4,7-10,15-17H,11-14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-MPEP from rat mGluR5 expressed in HEK293 cells				Bioorg Med Chem Lett 21: 195-9 (2010) Article DOI: 10.1016/j.bmcl.2010.11.038 BindingDB Entry DOI: 10.7270/Q2GQ6Z02
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50319800 ((3-methoxy-4-(naphthalen-1-yl)phenyl)((1S,5R)-1,3,...) Show SMILES COc1cc(ccc1-c1cccc2ccccc12)C(=O)N1C[C@]2(C)C[C@H]1CC(C)(C)C2 |r| Show InChI InChI=1S/C28H31NO2/c1-27(2)15-21-16-28(3,17-27)18-29(21)26(30)20-12-13-24(25(14-20)31-4)23-11-7-9-19-8-5-6-10-22(19)23/h5-14,21H,15-18H2,1-4H3/t21-,28-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement [3H]Arg human recombinant Vasopressin V1a receptor				Bioorg Med Chem Lett 20: 3742-5 (2010) Article DOI: 10.1016/j.bmcl.2010.04.068 BindingDB Entry DOI: 10.7270/Q24F1QW2
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50319804 ((3-methoxy-4-(quinolin-3-yl)phenyl)((1S,5R)-1,3,3-...) Show SMILES COc1cc(ccc1-c1cnc2ccccc2c1)C(=O)N1C[C@]2(C)C[C@H]1CC(C)(C)C2 |r| Show InChI InChI=1S/C27H30N2O2/c1-26(2)13-21-14-27(3,16-26)17-29(21)25(30)19-9-10-22(24(12-19)31-4)20-11-18-7-5-6-8-23(18)28-15-20/h5-12,15,21H,13-14,16-17H2,1-4H3/t21-,27-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement [3H]Arg human recombinant Vasopressin V1a receptor				Bioorg Med Chem Lett 20: 3742-5 (2010) Article DOI: 10.1016/j.bmcl.2010.04.068 BindingDB Entry DOI: 10.7270/Q24F1QW2
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50319770 ((2-chloro-4-(4-(quinolin-8-yl)naphthalen-1-yl)phen...) Show SMILES C[C@@]12C[C@@H](CC(C)(C)C1)N(C2)C(=O)c1ccc(cc1Cl)-c1ccc(-c2cccc3cccnc23)c2ccccc12 |r| Show InChI InChI=1S/C36H33ClN2O/c1-35(2)19-25-20-36(3,21-35)22-39(25)34(40)31-14-13-24(18-32(31)37)26-15-16-29(28-11-5-4-10-27(26)28)30-12-6-8-23-9-7-17-38-33(23)30/h4-18,25H,19-22H2,1-3H3/t25-,36-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement [3H]Arg human recombinant Vasopressin V1a receptor				Bioorg Med Chem Lett 20: 3742-5 (2010) Article DOI: 10.1016/j.bmcl.2010.04.068 BindingDB Entry DOI: 10.7270/Q24F1QW2
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM50319766 ((2',3,3'-trichloro-4'-(quinolin-8-yl)biphenyl-4-yl...) Show SMILES C[C@@]12C[C@@H](CC(C)(C)C1)N(C2)C(=O)c1ccc(cc1Cl)-c1ccc(c(Cl)c1Cl)-c1cccc2cccnc12 |r| Show InChI InChI=1S/C32H29Cl3N2O/c1-31(2)15-21-16-32(3,17-31)18-37(21)30(38)25-10-9-20(14-26(25)33)22-11-12-23(28(35)27(22)34)24-8-4-6-19-7-5-13-36-29(19)24/h4-14,21H,15-18H2,1-3H3/t21-,32-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement [3H]Arg human recombinant Vasopressin V2 receptor				Bioorg Med Chem Lett 20: 3742-5 (2010) Article DOI: 10.1016/j.bmcl.2010.04.068 BindingDB Entry DOI: 10.7270/Q24F1QW2
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50319775 ((3-chloro-2'-methylbiphenyl-4-yl)((1R,5S)-1,3,3-tr...) Show SMILES Cc1ccccc1-c1ccc(C(=O)N2C[C@@]3(C)C[C@@H]2CC(C)(C)C3)c(Cl)c1 |r| Show InChI InChI=1S/C24H28ClNO/c1-16-7-5-6-8-19(16)17-9-10-20(21(25)11-17)22(27)26-15-24(4)13-18(26)12-23(2,3)14-24/h5-11,18H,12-15H2,1-4H3/t18-,24-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement [3H]Arg human recombinant Vasopressin V1a receptor				Bioorg Med Chem Lett 20: 3742-5 (2010) Article DOI: 10.1016/j.bmcl.2010.04.068 BindingDB Entry DOI: 10.7270/Q24F1QW2
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50319789 ((2''-Methoxy-[1,1'3',1'']terphenyl-4''-yl)-((1S,5R...) Show SMILES COc1cc(ccc1-c1cccc(c1)-c1ccccc1)C(=O)N1C[C@]2(C)C[C@H]1CC(C)(C)C2 |r| Show InChI InChI=1S/C30H33NO2/c1-29(2)17-25-18-30(3,19-29)20-31(25)28(32)24-13-14-26(27(16-24)33-4)23-12-8-11-22(15-23)21-9-6-5-7-10-21/h5-16,25H,17-20H2,1-4H3/t25-,30-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement [3H]Arg human recombinant Vasopressin V1a receptor				Bioorg Med Chem Lett 20: 3742-5 (2010) Article DOI: 10.1016/j.bmcl.2010.04.068 BindingDB Entry DOI: 10.7270/Q24F1QW2
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM50319797 ((4-(benzo[b]thiophen-3-yl)-3-methoxyphenyl)((1S,5R...) Show SMILES COc1cc(ccc1-c1csc2ccccc12)C(=O)N1C[C@]2(C)C[C@H]1CC(C)(C)C2 |r| Show InChI InChI=1S/C26H29NO2S/c1-25(2)12-18-13-26(3,15-25)16-27(18)24(28)17-9-10-19(22(11-17)29-4)21-14-30-23-8-6-5-7-20(21)23/h5-11,14,18H,12-13,15-16H2,1-4H3/t18-,26-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement [3H]Arg human recombinant Vasopressin V2 receptor				Bioorg Med Chem Lett 20: 3742-5 (2010) Article DOI: 10.1016/j.bmcl.2010.04.068 BindingDB Entry DOI: 10.7270/Q24F1QW2
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50319801 ((3-methoxy-4-(naphthalen-2-yl)phenyl)((1S,5R)-1,3,...) Show SMILES COc1cc(ccc1-c1ccc2ccccc2c1)C(=O)N1C[C@]2(C)C[C@H]1CC(C)(C)C2 |r| Show InChI InChI=1S/C28H31NO2/c1-27(2)15-23-16-28(3,17-27)18-29(23)26(30)22-11-12-24(25(14-22)31-4)21-10-9-19-7-5-6-8-20(19)13-21/h5-14,23H,15-18H2,1-4H3/t23-,28-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement [3H]Arg human recombinant Vasopressin V1a receptor				Bioorg Med Chem Lett 20: 3742-5 (2010) Article DOI: 10.1016/j.bmcl.2010.04.068 BindingDB Entry DOI: 10.7270/Q24F1QW2
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50334108 ((4-methoxy-3-(pyridin-2-ylethynyl)phenyl)(4-(5-met...) Show SMILES COc1ccc(cc1C#Cc1ccccn1)C(=O)N1CCN(CC1)c1ccc(C)cn1 Show InChI InChI=1S/C25H24N4O2/c1-19-6-11-24(27-18-19)28-13-15-29(16-14-28)25(30)21-8-10-23(31-2)20(17-21)7-9-22-5-3-4-12-26-22/h3-6,8,10-12,17-18H,13-16H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-MPEP from rat mGluR5 expressed in HEK293 cells				Bioorg Med Chem Lett 21: 195-9 (2010) Article DOI: 10.1016/j.bmcl.2010.11.038 BindingDB Entry DOI: 10.7270/Q2GQ6Z02
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50334107 ((4-methoxy-3-(phenylethynyl)phenyl)(4-(pyridin-2-y...) Show SMILES COc1ccc(cc1C#Cc1ccccc1)C(=O)N1CCN(CC1)c1ccccn1 Show InChI InChI=1S/C25H23N3O2/c1-30-23-13-12-22(19-21(23)11-10-20-7-3-2-4-8-20)25(29)28-17-15-27(16-18-28)24-9-5-6-14-26-24/h2-9,12-14,19H,15-18H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-MPEP from rat mGluR5 expressed in HEK293 cells				Bioorg Med Chem Lett 21: 195-9 (2010) Article DOI: 10.1016/j.bmcl.2010.11.038 BindingDB Entry DOI: 10.7270/Q2GQ6Z02
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50319778 ((2-methoxy-2'-methylbiphenyl-4-yl)((1S,5R)-1,3,3-t...) Show SMILES COc1cc(ccc1-c1ccccc1C)C(=O)N1C[C@]2(C)C[C@H]1CC(C)(C)C2 |r| Show InChI InChI=1S/C25H31NO2/c1-17-8-6-7-9-20(17)21-11-10-18(12-22(21)28-5)23(27)26-16-25(4)14-19(26)13-24(2,3)15-25/h6-12,19H,13-16H2,1-5H3/t19-,25-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement [3H]Arg human recombinant Vasopressin V1a receptor				Bioorg Med Chem Lett 20: 3742-5 (2010) Article DOI: 10.1016/j.bmcl.2010.04.068 BindingDB Entry DOI: 10.7270/Q24F1QW2
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50334109 ((4-methoxy-3-(pyridin-2-ylethynyl)phenyl)(4-(pyrid...) Show SMILES COc1ccc(cc1C#Cc1ccccn1)C(=O)N1CCN(CC1)c1ccccn1 Show InChI InChI=1S/C24H22N4O2/c1-30-22-11-9-20(18-19(22)8-10-21-6-2-4-12-25-21)24(29)28-16-14-27(15-17-28)23-7-3-5-13-26-23/h2-7,9,11-13,18H,14-17H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-MPEP from rat mGluR5 expressed in HEK293 cells				Bioorg Med Chem Lett 21: 195-9 (2010) Article DOI: 10.1016/j.bmcl.2010.11.038 BindingDB Entry DOI: 10.7270/Q2GQ6Z02
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM50319813 ((4-(4-(benzo[b]thiophen-3-yl)naphthalen-1-yl)-2-ch...) Show SMILES C[C@@]12C[C@@H](CC(C)(C)C1)N(C2)C(=O)c1ccc(cc1Cl)-c1ccc(-c2csc3ccccc23)c2ccccc12 |r| Show InChI InChI=1S/C35H32ClNOS/c1-34(2)17-23-18-35(3,20-34)21-37(23)33(38)29-13-12-22(16-31(29)36)24-14-15-27(26-9-5-4-8-25(24)26)30-19-39-32-11-7-6-10-28(30)32/h4-16,19,23H,17-18,20-21H2,1-3H3/t23-,35-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement [3H]Arg human recombinant Vasopressin V2 receptor				Bioorg Med Chem Lett 20: 3742-5 (2010) Article DOI: 10.1016/j.bmcl.2010.04.068 BindingDB Entry DOI: 10.7270/Q24F1QW2
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50319783 ((2-methoxy-2'-phenoxybiphenyl-4-yl)((1S,5R)-1,3,3-...) Show SMILES COc1cc(ccc1-c1ccccc1Oc1ccccc1)C(=O)N1C[C@]2(C)C[C@H]1CC(C)(C)C2 |r| Show InChI InChI=1S/C30H33NO3/c1-29(2)17-22-18-30(3,19-29)20-31(22)28(32)21-14-15-25(27(16-21)33-4)24-12-8-9-13-26(24)34-23-10-6-5-7-11-23/h5-16,22H,17-20H2,1-4H3/t22-,30-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	22.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement [3H]Arg human recombinant Vasopressin V1a receptor				Bioorg Med Chem Lett 20: 3742-5 (2010) Article DOI: 10.1016/j.bmcl.2010.04.068 BindingDB Entry DOI: 10.7270/Q24F1QW2
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50319805 ((3-methoxy-4-(quinolin-5-yl)phenyl)((1S,5R)-1,3,3-...) Show SMILES COc1cc(ccc1-c1cccc2ncccc12)C(=O)N1C[C@]2(C)C[C@H]1CC(C)(C)C2 |r| Show InChI InChI=1S/C27H30N2O2/c1-26(2)14-19-15-27(3,16-26)17-29(19)25(30)18-10-11-22(24(13-18)31-4)20-7-5-9-23-21(20)8-6-12-28-23/h5-13,19H,14-17H2,1-4H3/t19-,27-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	23.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement [3H]Arg human recombinant Vasopressin V1a receptor				Bioorg Med Chem Lett 20: 3742-5 (2010) Article DOI: 10.1016/j.bmcl.2010.04.068 BindingDB Entry DOI: 10.7270/Q24F1QW2
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50334110 ((4-methoxy-3-(thiazol-2-ylethynyl)phenyl)(4-(pyrid...) Show SMILES COc1ccc(cc1C#Cc1nccs1)C(=O)N1CCN(CC1)c1ccccn1 Show InChI InChI=1S/C22H20N4O2S/c1-28-19-7-5-18(16-17(19)6-8-21-24-10-15-29-21)22(27)26-13-11-25(12-14-26)20-4-2-3-9-23-20/h2-5,7,9-10,15-16H,11-14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-MPEP from rat mGluR5 expressed in HEK293 cells				Bioorg Med Chem Lett 21: 195-9 (2010) Article DOI: 10.1016/j.bmcl.2010.11.038 BindingDB Entry DOI: 10.7270/Q2GQ6Z02
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50319781 ((2-chloro-5-methoxy-2'-methylbiphenyl-4-yl)((1R,5S...) Show SMILES COc1cc(c(Cl)cc1C(=O)N1C[C@@]2(C)C[C@@H]1CC(C)(C)C2)-c1ccccc1C |r| Show InChI InChI=1S/C25H30ClNO2/c1-16-8-6-7-9-18(16)19-11-22(29-5)20(10-21(19)26)23(28)27-15-25(4)13-17(27)12-24(2,3)14-25/h6-11,17H,12-15H2,1-5H3/t17-,25-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement [3H]Arg human recombinant Vasopressin V1a receptor				Bioorg Med Chem Lett 20: 3742-5 (2010) Article DOI: 10.1016/j.bmcl.2010.04.068 BindingDB Entry DOI: 10.7270/Q24F1QW2
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50334111 ((4-methoxy-3-(phenylethynyl)phenyl)(4-(pyrazin-2-y...) Show SMILES COc1ccc(cc1C#Cc1ccccc1)C(=O)N1CCN(CC1)c1cnccn1 Show InChI InChI=1S/C24H22N4O2/c1-30-22-10-9-21(17-20(22)8-7-19-5-3-2-4-6-19)24(29)28-15-13-27(14-16-28)23-18-25-11-12-26-23/h2-6,9-12,17-18H,13-16H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-MPEP from rat mGluR5 expressed in HEK293 cells				Bioorg Med Chem Lett 21: 195-9 (2010) Article DOI: 10.1016/j.bmcl.2010.11.038 BindingDB Entry DOI: 10.7270/Q2GQ6Z02
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM50319788 (CHEMBL1084325 | N-(2'-methoxy-4'-((1S,5R)-1,3,3-tr...) Show SMILES COc1cc(ccc1-c1cccc(NC(C)=O)c1)C(=O)N1C[C@]2(C)C[C@H]1CC(C)(C)C2 |r| Show InChI InChI=1S/C26H32N2O3/c1-17(29)27-20-8-6-7-18(11-20)22-10-9-19(12-23(22)31-5)24(30)28-16-26(4)14-21(28)13-25(2,3)15-26/h6-12,21H,13-16H2,1-5H3,(H,27,29)/t21-,26-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement [3H]Arg human recombinant Vasopressin V2 receptor				Bioorg Med Chem Lett 20: 3742-5 (2010) Article DOI: 10.1016/j.bmcl.2010.04.068 BindingDB Entry DOI: 10.7270/Q24F1QW2
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50334112 ((4-methoxy-3-(pyridin-2-ylethynyl)phenyl)(4-(pyrim...) Show SMILES COc1ccc(cc1C#Cc1ccccn1)C(=O)N1CCN(CC1)c1ccncn1 Show InChI InChI=1S/C23H21N5O2/c1-30-21-8-6-19(16-18(21)5-7-20-4-2-3-10-25-20)23(29)28-14-12-27(13-15-28)22-9-11-24-17-26-22/h2-4,6,8-11,16-17H,12-15H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-MPEP from rat mGluR5 expressed in HEK293 cells				Bioorg Med Chem Lett 21: 195-9 (2010) Article DOI: 10.1016/j.bmcl.2010.11.038 BindingDB Entry DOI: 10.7270/Q2GQ6Z02
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50319766 ((2',3,3'-trichloro-4'-(quinolin-8-yl)biphenyl-4-yl...) Show SMILES C[C@@]12C[C@@H](CC(C)(C)C1)N(C2)C(=O)c1ccc(cc1Cl)-c1ccc(c(Cl)c1Cl)-c1cccc2cccnc12 |r| Show InChI InChI=1S/C32H29Cl3N2O/c1-31(2)15-21-16-32(3,17-31)18-37(21)30(38)25-10-9-20(14-26(25)33)22-11-12-23(28(35)27(22)34)24-8-4-6-19-7-5-13-36-29(19)24/h4-14,21H,15-18H2,1-3H3/t21-,32-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	33.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement [3H]Arg human recombinant Vasopressin V1a receptor				Bioorg Med Chem Lett 20: 3742-5 (2010) Article DOI: 10.1016/j.bmcl.2010.04.068 BindingDB Entry DOI: 10.7270/Q24F1QW2
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50334113 ((4-methoxy-3-((6-methylpyridin-2-yl)ethynyl)phenyl...) Show SMILES COc1ccc(cc1C#Cc1cccc(C)n1)C(=O)N1CCN(CC1)c1ccccn1 Show InChI InChI=1S/C25H24N4O2/c1-19-6-5-7-22(27-19)11-9-20-18-21(10-12-23(20)31-2)25(30)29-16-14-28(15-17-29)24-8-3-4-13-26-24/h3-8,10,12-13,18H,14-17H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]-MPEP from rat mGluR5 expressed in HEK293 cells				Bioorg Med Chem Lett 21: 195-9 (2010) Article DOI: 10.1016/j.bmcl.2010.11.038 BindingDB Entry DOI: 10.7270/Q2GQ6Z02
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50319777 ((2,2'-dimethylbiphenyl-4-yl)((1R,5S)-1,3,3-trimeth...) Show SMILES Cc1ccccc1-c1ccc(cc1C)C(=O)N1C[C@@]2(C)C[C@@H]1CC(C)(C)C2 |r| Show InChI InChI=1S/C25H31NO/c1-17-8-6-7-9-21(17)22-11-10-19(12-18(22)2)23(27)26-16-25(5)14-20(26)13-24(3,4)15-25/h6-12,20H,13-16H2,1-5H3/t20-,25-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement [3H]Arg human recombinant Vasopressin V1a receptor				Bioorg Med Chem Lett 20: 3742-5 (2010) Article DOI: 10.1016/j.bmcl.2010.04.068 BindingDB Entry DOI: 10.7270/Q24F1QW2
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM50319812 ((4-(benzo[b]thiophen-3-yl)-5-chloro-2-methoxypheny...) Show SMILES COc1cc(-c2csc3ccccc23)c(Cl)cc1C(=O)N1C[C@]2(C)C[C@H]1CC(C)(C)C2 |r| Show InChI InChI=1S/C26H28ClNO2S/c1-25(2)11-16-12-26(3,14-25)15-28(16)24(29)19-9-21(27)18(10-22(19)30-4)20-13-31-23-8-6-5-7-17(20)23/h5-10,13,16H,11-12,14-15H2,1-4H3/t16-,26-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	36.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement [3H]Arg human recombinant Vasopressin V2 receptor				Bioorg Med Chem Lett 20: 3742-5 (2010) Article DOI: 10.1016/j.bmcl.2010.04.068 BindingDB Entry DOI: 10.7270/Q24F1QW2
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50319768 ((2',3-dichloro-4'-(quinolin-8-yl)biphenyl-4-yl)((1...) Show SMILES C[C@@]12C[C@@H](CC(C)(C)C1)N(C2)C(=O)c1ccc(cc1Cl)-c1ccc(cc1Cl)-c1cccc2cccnc12 |r| Show InChI InChI=1S/C32H30Cl2N2O/c1-31(2)16-23-17-32(3,18-31)19-36(23)30(37)26-12-10-21(14-28(26)34)24-11-9-22(15-27(24)33)25-8-4-6-20-7-5-13-35-29(20)25/h4-15,23H,16-19H2,1-3H3/t23-,32-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	38.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement [3H]Arg human recombinant Vasopressin V1a receptor				Bioorg Med Chem Lett 20: 3742-5 (2010) Article DOI: 10.1016/j.bmcl.2010.04.068 BindingDB Entry DOI: 10.7270/Q24F1QW2
					More data for this Ligand-Target Pair
Vasopressin V1a receptor (Homo sapiens (Human))	BDBM50319798 ((4-(dibenzo[b,d]furan-4-yl)-3-methoxyphenyl)((1S,5...) Show SMILES COc1cc(ccc1-c1cccc2c3ccccc3oc12)C(=O)N1C[C@]2(C)C[C@H]1CC(C)(C)C2 |r| Show InChI InChI=1S/C30H31NO3/c1-29(2)15-20-16-30(3,17-29)18-31(20)28(32)19-12-13-22(26(14-19)33-4)24-10-7-9-23-21-8-5-6-11-25(21)34-27(23)24/h5-14,20H,15-18H2,1-4H3/t20-,30-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	38.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement [3H]Arg human recombinant Vasopressin V1a receptor				Bioorg Med Chem Lett 20: 3742-5 (2010) Article DOI: 10.1016/j.bmcl.2010.04.068 BindingDB Entry DOI: 10.7270/Q24F1QW2
					More data for this Ligand-Target Pair

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