Compile Data Set for Download or QSAR

Found 169 hits with Last Name = 'kezar' and Initial = 'hs'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Delta-type opioid receptor (Homo sapiens (Human))	BDBM21864 ((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...) Show SMILES [H][C@@]12Cc3ccc(O)c4OC5c6[nH]c7ccccc7c6CC1(O)C5(CCN2CC1CC1)c34 |THB:27:26:21:31.2.3| Show InChI InChI=1S/C26H26N2O3/c29-19-8-7-15-11-20-26(30)12-17-16-3-1-2-4-18(16)27-22(17)24-25(26,21(15)23(19)31-24)9-10-28(20)13-14-5-6-14/h1-4,7-8,14,20,24,27,29-30H,5-6,9-13H2/t20-,24?,25?,26?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	0.0400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Antagonist activity on agonist stimulated [35S]GTP-gamma-S, binding in guinea pig caudate membranes (10 uM SNC-80 as the agonist ligand for delta-rec...				Bioorg Med Chem Lett 13: 529-32 (2003) BindingDB Entry DOI: 10.7270/Q27S7P9P
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM82551 (C18130 | CAS_105618-26-6 | NOR-BNI (HCI)2 | NORBNI) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2[C@@H]4Oc6c7c(C[C@H]8N(CC9CC9)CC[C@@]47[C@@]8(O)Cc2c1C[C@@]35O)ccc6O |r| Show InChI InChI=1S/C40H43N3O6/c44-25-7-5-21-13-27-39(46)15-23-24-16-40(47)28-14-22-6-8-26(45)34-30(22)38(40,10-12-43(28)18-20-3-4-20)36(49-34)32(24)41-31(23)35-37(39,29(21)33(25)48-35)9-11-42(27)17-19-1-2-19/h5-8,19-20,27-28,35-36,41,44-47H,1-4,9-18H2/t27-,28-,35+,36+,37+,38+,39-,40-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	PubMed	0.120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Antagonist activity on agonist stimulated [35S]GTP-gamma-S, binding in guinea pig caudate membranes (10 uM U69,593 as the agonist ligand for kappa-re...				Bioorg Med Chem Lett 13: 529-32 (2003) BindingDB Entry DOI: 10.7270/Q27S7P9P
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50123279 (19-cyclopropylmethyl-6-(1H-1-pyrrolyl)-11-oxa-8,19...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncc(cc1C[C@@]35O)-n1cccc1 Show InChI InChI=1S/C27H27N3O3/c31-20-6-5-17-12-21-27(32)13-18-11-19(29-8-1-2-9-29)14-28-23(18)25-26(27,22(17)24(20)33-25)7-10-30(21)15-16-3-4-16/h1-2,5-6,8-9,11,14,16,21,25,31-32H,3-4,7,10,12-13,15H2/t21-,25+,26+,27-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Antagonist activity on agonist stimulated [35S]GTP-gamma-S, binding in guinea pig caudate membranes (10 uM SNC-80 as the agonist ligand for delta-rec...				Bioorg Med Chem Lett 13: 529-32 (2003) BindingDB Entry DOI: 10.7270/Q27S7P9P
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM21864 ((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...) Show SMILES [H][C@@]12Cc3ccc(O)c4OC5c6[nH]c7ccccc7c6CC1(O)C5(CCN2CC1CC1)c34 |THB:27:26:21:31.2.3| Show InChI InChI=1S/C26H26N2O3/c29-19-8-7-15-11-20-26(30)12-17-16-3-1-2-4-18(16)27-22(17)24-25(26,21(15)23(19)31-24)9-10-28(20)13-14-5-6-14/h1-4,7-8,14,20,24,27,29-30H,5-6,9-13H2/t20-,24?,25?,26?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	0.410	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Binding affinity to delta opioid receptor was measured using [3H]DADLE				Bioorg Med Chem Lett 13: 529-32 (2003) BindingDB Entry DOI: 10.7270/Q27S7P9P
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM21864 ((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...) Show SMILES [H][C@@]12Cc3ccc(O)c4OC5c6[nH]c7ccccc7c6CC1(O)C5(CCN2CC1CC1)c34 |THB:27:26:21:31.2.3| Show InChI InChI=1S/C26H26N2O3/c29-19-8-7-15-11-20-26(30)12-17-16-3-1-2-4-18(16)27-22(17)24-25(26,21(15)23(19)31-24)9-10-28(20)13-14-5-6-14/h1-4,7-8,14,20,24,27,29-30H,5-6,9-13H2/t20-,24?,25?,26?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	0.410	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Binding affinity for Opioid receptor delta 1 was determined by inhibition of binding of [3H]DADLE (1.3-2.0 nM) to rat brain membranes				J Med Chem 42: 3527-38 (1999) Article DOI: 10.1021/jm990039i BindingDB Entry DOI: 10.7270/Q2QR4XSQ
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50123279 (19-cyclopropylmethyl-6-(1H-1-pyrrolyl)-11-oxa-8,19...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncc(cc1C[C@@]35O)-n1cccc1 Show InChI InChI=1S/C27H27N3O3/c31-20-6-5-17-12-21-27(32)13-18-11-19(29-8-1-2-9-29)14-28-23(18)25-26(27,22(17)24(20)33-25)7-10-30(21)15-16-3-4-16/h1-2,5-6,8-9,11,14,16,21,25,31-32H,3-4,7,10,12-13,15H2/t21-,25+,26+,27-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.640	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Binding affinity to delta opioid receptor was measured using [3H]DADLE				Bioorg Med Chem Lett 13: 529-32 (2003) BindingDB Entry DOI: 10.7270/Q27S7P9P
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50123274 (6-amino(imino)methylamino-19-cyclopropylmethyl-11-...) Show SMILES [#7]\[#6](-[#7])=[#7]/c1cnc2-[#6@@H]3-[#8]-c4c5c(-[#6]-[#6@H]6-[#7](-[#6]-[#6]-7-[#6]-[#6]-7)-[#6]-[#6][C@@]35[C@@]6([#8])[#6]-c2c1)ccc4-[#8] Show InChI InChI=1S/C24H27N5O3/c25-22(26)28-15-7-14-9-24(31)17-8-13-3-4-16(30)20-18(13)23(24,21(32-20)19(14)27-10-15)5-6-29(17)11-12-1-2-12/h3-4,7,10,12,17,21,30-31H,1-2,5-6,8-9,11H2,(H4,25,26,28)/t17-,21+,23+,24-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Binding affinity for kappa opioid receptor was measured using [3H]U-69593				Bioorg Med Chem Lett 13: 529-32 (2003) BindingDB Entry DOI: 10.7270/Q27S7P9P
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50123273 (19-cyclopropylmethyl-(2S,10R)-11-oxa-8,19-diazahex...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncccc1C[C@@]35O Show InChI InChI=1S/C23H24N2O3/c26-16-6-5-14-10-17-23(27)11-15-2-1-8-24-19(15)21-22(23,18(14)20(16)28-21)7-9-25(17)12-13-3-4-13/h1-2,5-6,8,13,17,21,26-27H,3-4,7,9-12H2/t17-,21+,22+,23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.780	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Binding affinity to delta opioid receptor was measured using [3H]DADLE				Bioorg Med Chem Lett 13: 529-32 (2003) BindingDB Entry DOI: 10.7270/Q27S7P9P
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50123273 (19-cyclopropylmethyl-(2S,10R)-11-oxa-8,19-diazahex...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncccc1C[C@@]35O Show InChI InChI=1S/C23H24N2O3/c26-16-6-5-14-10-17-23(27)11-15-2-1-8-24-19(15)21-22(23,18(14)20(16)28-21)7-9-25(17)12-13-3-4-13/h1-2,5-6,8,13,17,21,26-27H,3-4,7,9-12H2/t17-,21+,22+,23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.780	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Binding affinity for Opioid receptor delta 1 was determined by inhibition of binding of [3H]DADLE (1.3-2.0 nM) to rat brain membranes				J Med Chem 42: 3527-38 (1999) Article DOI: 10.1021/jm990039i BindingDB Entry DOI: 10.7270/Q2QR4XSQ
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50001196 (CHEMBL610522) Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)Cc1cc(cnc21)-c1ccccc1)ccc3O |r,THB:10:9:17:4.5.6| Show InChI InChI=1S/C29H28N2O3/c32-22-9-8-19-13-23-29(33)14-20-12-21(18-4-2-1-3-5-18)15-30-25(20)27-28(29,24(19)26(22)34-27)10-11-31(23)16-17-6-7-17/h1-5,8-9,12,15,17,23,27,32-33H,6-7,10-11,13-14,16H2/t23-,27+,28+,29-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.870	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Binding affinity for Opioid receptor delta 1 was determined by inhibition of binding of [3H]DADLE (1.3-2.0 nM) to rat brain membranes				J Med Chem 42: 3527-38 (1999) Article DOI: 10.1021/jm990039i BindingDB Entry DOI: 10.7270/Q2QR4XSQ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50123274 (6-amino(imino)methylamino-19-cyclopropylmethyl-11-...) Show SMILES [#7]\[#6](-[#7])=[#7]/c1cnc2-[#6@@H]3-[#8]-c4c5c(-[#6]-[#6@H]6-[#7](-[#6]-[#6]-7-[#6]-[#6]-7)-[#6]-[#6][C@@]35[C@@]6([#8])[#6]-c2c1)ccc4-[#8] Show InChI InChI=1S/C24H27N5O3/c25-22(26)28-15-7-14-9-24(31)17-8-13-3-4-16(30)20-18(13)23(24,21(32-20)19(14)27-10-15)5-6-29(17)11-12-1-2-12/h3-4,7,10,12,17,21,30-31H,1-2,5-6,8-9,11H2,(H4,25,26,28)/t17-,21+,23+,24-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Antagonist activity on agonist stimulated [35S]GTP-gamma-S, binding in guinea pig caudate membranes (10 uM U69,593 as the agonist ligand for kappa-re...				Bioorg Med Chem Lett 13: 529-32 (2003) BindingDB Entry DOI: 10.7270/Q27S7P9P
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50123271 (19-cyclopropylmethyl-6-bromo-11-oxa-8,19-diazahexa...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncc(Br)cc1C[C@@]35O Show InChI InChI=1S/C23H23BrN2O3/c24-15-7-14-9-23(28)17-8-13-3-4-16(27)20-18(13)22(23,21(29-20)19(14)25-10-15)5-6-26(17)11-12-1-2-12/h3-4,7,10,12,17,21,27-28H,1-2,5-6,8-9,11H2/t17-,21+,22+,23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Binding affinity to delta opioid receptor was measured using [3H]DADLE				Bioorg Med Chem Lett 13: 529-32 (2003) BindingDB Entry DOI: 10.7270/Q27S7P9P
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50123275 (19-cyclopropylmethyl-6-benzylamino-11-oxa-8,19-dia...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncc(NCc2ccccc2)cc1C[C@@]35O Show InChI InChI=1S/C30H31N3O3/c34-23-9-8-20-13-24-30(35)14-21-12-22(31-15-18-4-2-1-3-5-18)16-32-26(21)28-29(30,25(20)27(23)36-28)10-11-33(24)17-19-6-7-19/h1-5,8-9,12,16,19,24,28,31,34-35H,6-7,10-11,13-15,17H2/t24-,28+,29+,30-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Binding affinity to delta opioid receptor was measured using [3H]DADLE				Bioorg Med Chem Lett 13: 529-32 (2003) BindingDB Entry DOI: 10.7270/Q27S7P9P
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50123273 (19-cyclopropylmethyl-(2S,10R)-11-oxa-8,19-diazahex...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncccc1C[C@@]35O Show InChI InChI=1S/C23H24N2O3/c26-16-6-5-14-10-17-23(27)11-15-2-1-8-24-19(15)21-22(23,18(14)20(16)28-21)7-9-25(17)12-13-3-4-13/h1-2,5-6,8,13,17,21,26-27H,3-4,7,9-12H2/t17-,21+,22+,23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Binding affinity for Opioid receptor mu 1 was determined by inhibition of binding of [3H]DAMGO (1.4-3 nM) to rat brain membranes				J Med Chem 42: 3527-38 (1999) Article DOI: 10.1021/jm990039i BindingDB Entry DOI: 10.7270/Q2QR4XSQ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50123273 (19-cyclopropylmethyl-(2S,10R)-11-oxa-8,19-diazahex...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncccc1C[C@@]35O Show InChI InChI=1S/C23H24N2O3/c26-16-6-5-14-10-17-23(27)11-15-2-1-8-24-19(15)21-22(23,18(14)20(16)28-21)7-9-25(17)12-13-3-4-13/h1-2,5-6,8,13,17,21,26-27H,3-4,7,9-12H2/t17-,21+,22+,23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Binding affinity to mu opioid receptor was measured using [3H]DAMGO				Bioorg Med Chem Lett 13: 529-32 (2003) BindingDB Entry DOI: 10.7270/Q27S7P9P
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM21864 ((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...) Show SMILES [H][C@@]12Cc3ccc(O)c4OC5c6[nH]c7ccccc7c6CC1(O)C5(CCN2CC1CC1)c34 |THB:27:26:21:31.2.3| Show InChI InChI=1S/C26H26N2O3/c29-19-8-7-15-11-20-26(30)12-17-16-3-1-2-4-18(16)27-22(17)24-25(26,21(15)23(19)31-24)9-10-28(20)13-14-5-6-14/h1-4,7-8,14,20,24,27,29-30H,5-6,9-13H2/t20-,24?,25?,26?/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Antagonist activity on agonist stimulated [35S]GTP-gamma-S, binding in guinea pig caudate membranes (10 uM DAMGO as the agonist ligand for mu-recepto...				Bioorg Med Chem Lett 13: 529-32 (2003) BindingDB Entry DOI: 10.7270/Q27S7P9P
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50123277 (19-cyclopropylmethyl-6-phenyleaminomethyl-11-oxa-8...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncc(CNc2ccccc2)cc1C[C@@]35O Show InChI InChI=1S/C30H31N3O3/c34-23-9-8-20-13-24-30(35)14-21-12-19(15-31-22-4-2-1-3-5-22)16-32-26(21)28-29(30,25(20)27(23)36-28)10-11-33(24)17-18-6-7-18/h1-5,8-9,12,16,18,24,28,31,34-35H,6-7,10-11,13-15,17H2/t24-,28+,29+,30-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Binding affinity to delta opioid receptor was measured using [3H]DADLE				Bioorg Med Chem Lett 13: 529-32 (2003) BindingDB Entry DOI: 10.7270/Q27S7P9P
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50001190 (CHEMBL2112576) Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)Cc1ccc(nc21)-c1ccccc1)ccc3O |THB:10:9:17:4.5.6| Show InChI InChI=1S/C29H28N2O3/c32-22-11-9-19-14-23-29(33)15-20-8-10-21(18-4-2-1-3-5-18)30-25(20)27-28(29,24(19)26(22)34-27)12-13-31(23)16-17-6-7-17/h1-5,8-11,17,23,27,32-33H,6-7,12-16H2/t23-,27+,28+,29-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Binding affinity for Opioid receptor delta 1 was determined by inhibition of binding of [3H]DADLE (1.3-2.0 nM) to rat brain membranes				J Med Chem 42: 3527-38 (1999) Article DOI: 10.1021/jm990039i BindingDB Entry DOI: 10.7270/Q2QR4XSQ
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50001195 (CHEMBL610261) Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)Cc1cc(cnc21)-c1ccc(Cl)cc1)ccc3O |r,THB:10:9:17:4.5.6| Show InChI InChI=1S/C29H27ClN2O3/c30-21-6-3-17(4-7-21)20-11-19-13-29(34)23-12-18-5-8-22(33)26-24(18)28(29,27(35-26)25(19)31-14-20)9-10-32(23)15-16-1-2-16/h3-8,11,14,16,23,27,33-34H,1-2,9-10,12-13,15H2/t23-,27+,28+,29-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Binding affinity for Opioid receptor delta 1 was determined by inhibition of binding of [3H]DADLE (1.3-2.0 nM) to rat brain membranes				J Med Chem 42: 3527-38 (1999) Article DOI: 10.1021/jm990039i BindingDB Entry DOI: 10.7270/Q2QR4XSQ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM60212 ((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O Show InChI InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Binding affinity for Opioid receptor mu 1 was determined by inhibition of binding of [3H]DAMGO (1.4-3 nM) to rat brain membranes				J Med Chem 42: 3527-38 (1999) Article DOI: 10.1021/jm990039i BindingDB Entry DOI: 10.7270/Q2QR4XSQ
					More data for this Ligand-Target Pair
Delta-type opioid receptor (MOUSE)	BDBM50001196 (CHEMBL610522) Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)Cc1cc(cnc21)-c1ccccc1)ccc3O |r,THB:10:9:17:4.5.6| Show InChI InChI=1S/C29H28N2O3/c32-22-9-8-19-13-23-29(33)14-20-12-21(18-4-2-1-3-5-18)15-30-25(20)27-28(29,24(19)26(22)34-27)10-11-31(23)16-17-6-7-17/h1-5,8-9,12,15,17,23,27,32-33H,6-7,10-11,13-14,16H2/t23-,27+,28+,29-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Antagonist potency measured as Ke = [antagonist]/(IC50 ratio-1) against delta opioid receptor from mouse vas deferens (MVD) using DPDPE				J Med Chem 42: 3527-38 (1999) Article DOI: 10.1021/jm990039i BindingDB Entry DOI: 10.7270/Q2QR4XSQ
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50001173 (CHEMBL2112572) Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)Cc1cncnc21)ccc3O |THB:10:9:17:4.5.6| Show InChI InChI=1S/C22H23N3O3/c26-15-4-3-13-7-16-22(27)8-14-9-23-11-24-18(14)20-21(22,17(13)19(15)28-20)5-6-25(16)10-12-1-2-12/h3-4,9,11-12,16,20,26-27H,1-2,5-8,10H2/t16-,20+,21+,22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Binding affinity for Opioid receptor delta 1 was determined by inhibition of binding of [3H]DADLE (1.3-2.0 nM) to rat brain membranes				J Med Chem 42: 3527-38 (1999) Article DOI: 10.1021/jm990039i BindingDB Entry DOI: 10.7270/Q2QR4XSQ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50123279 (19-cyclopropylmethyl-6-(1H-1-pyrrolyl)-11-oxa-8,19...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncc(cc1C[C@@]35O)-n1cccc1 Show InChI InChI=1S/C27H27N3O3/c31-20-6-5-17-12-21-27(32)13-18-11-19(29-8-1-2-9-29)14-28-23(18)25-26(27,22(17)24(20)33-25)7-10-30(21)15-16-3-4-16/h1-2,5-6,8-9,11,14,16,21,25,31-32H,3-4,7,10,12-13,15H2/t21-,25+,26+,27-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Antagonist activity on agonist stimulated [35S]GTP-gamma-S, binding in guinea pig caudate membranes (10 uM DAMGO as the agonist ligand for Mu-recepto...				Bioorg Med Chem Lett 13: 529-32 (2003) BindingDB Entry DOI: 10.7270/Q27S7P9P
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50001173 (CHEMBL2112572) Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)Cc1cncnc21)ccc3O |THB:10:9:17:4.5.6| Show InChI InChI=1S/C22H23N3O3/c26-15-4-3-13-7-16-22(27)8-14-9-23-11-24-18(14)20-21(22,17(13)19(15)28-20)5-6-25(16)10-12-1-2-12/h3-4,9,11-12,16,20,26-27H,1-2,5-8,10H2/t16-,20+,21+,22-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Binding affinity for Opioid receptor mu 1 was determined by inhibition of binding of [3H]DAMGO (1.4-3 nM) to rat brain membranes				J Med Chem 42: 3527-38 (1999) Article DOI: 10.1021/jm990039i BindingDB Entry DOI: 10.7270/Q2QR4XSQ
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50123272 (CHEMBL357680 | ethyl 19-cyclopropylmethyl-2,13-dih...) Show SMILES CCOC(=O)c1cnc2[C@@H]3Oc4c5c(C[C@H]6N(CC7CC7)CC[C@@]35[C@@]6(O)Cc2c1)ccc4O Show InChI InChI=1S/C26H28N2O5/c1-2-32-24(30)17-9-16-11-26(31)19-10-15-5-6-18(29)22-20(15)25(26,23(33-22)21(16)27-12-17)7-8-28(19)13-14-3-4-14/h5-6,9,12,14,19,23,29,31H,2-4,7-8,10-11,13H2,1H3/t19-,23+,25+,26-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Binding affinity to delta opioid receptor was measured using [3H]DADLE				Bioorg Med Chem Lett 13: 529-32 (2003) BindingDB Entry DOI: 10.7270/Q27S7P9P
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50123278 (19-cyclopropylmethyl-6-cyano-11-oxa-8,19-diazahexa...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncc(cc1C[C@@]35O)C#N Show InChI InChI=1S/C24H23N3O3/c25-10-14-7-16-9-24(29)18-8-15-3-4-17(28)21-19(15)23(24,22(30-21)20(16)26-11-14)5-6-27(18)12-13-1-2-13/h3-4,7,11,13,18,22,28-29H,1-2,5-6,8-9,12H2/t18-,22+,23+,24-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Binding affinity to delta opioid receptor was measured using [3H]DADLE				Bioorg Med Chem Lett 13: 529-32 (2003) BindingDB Entry DOI: 10.7270/Q27S7P9P
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50123280 (19-cyclopropylmethyl-6-nitro-11-oxa-8,19-diazahexa...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncc(cc1C[C@@]35O)[N+]([O-])=O Show InChI InChI=1S/C23H23N3O5/c27-16-4-3-13-8-17-23(28)9-14-7-15(26(29)30)10-24-19(14)21-22(23,18(13)20(16)31-21)5-6-25(17)11-12-1-2-12/h3-4,7,10,12,17,21,27-28H,1-2,5-6,8-9,11H2/t17-,21+,22+,23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Binding affinity to delta opioid receptor was measured using [3H]DADLE				Bioorg Med Chem Lett 13: 529-32 (2003) BindingDB Entry DOI: 10.7270/Q27S7P9P
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50123277 (19-cyclopropylmethyl-6-phenyleaminomethyl-11-oxa-8...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncc(CNc2ccccc2)cc1C[C@@]35O Show InChI InChI=1S/C30H31N3O3/c34-23-9-8-20-13-24-30(35)14-21-12-19(15-31-22-4-2-1-3-5-22)16-32-26(21)28-29(30,25(20)27(23)36-28)10-11-33(24)17-18-6-7-18/h1-5,8-9,12,16,18,24,28,31,34-35H,6-7,10-11,13-15,17H2/t24-,28+,29+,30-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Binding affinity to mu opioid receptor was measured using [3H]DAMGO				Bioorg Med Chem Lett 13: 529-32 (2003) BindingDB Entry DOI: 10.7270/Q27S7P9P
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM21864 ((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...) Show SMILES [H][C@@]12Cc3ccc(O)c4OC5c6[nH]c7ccccc7c6CC1(O)C5(CCN2CC1CC1)c34 |THB:27:26:21:31.2.3| Show InChI InChI=1S/C26H26N2O3/c29-19-8-7-15-11-20-26(30)12-17-16-3-1-2-4-18(16)27-22(17)24-25(26,21(15)23(19)31-24)9-10-28(20)13-14-5-6-14/h1-4,7-8,14,20,24,27,29-30H,5-6,9-13H2/t20-,24?,25?,26?/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Antagonist activity on agonist stimulated [35S]GTP-gamma-S, binding in guinea pig caudate membranes (10 uM U69,593 as the agonist ligand for kappa-re...				Bioorg Med Chem Lett 13: 529-32 (2003) BindingDB Entry DOI: 10.7270/Q27S7P9P
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50001191 (CHEMBL2112575) Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)Cc1cnc(C)nc21)ccc3O |THB:10:9:17:4.5.6| Show InChI InChI=1S/C23H25N3O3/c1-12-24-10-15-9-23(28)17-8-14-4-5-16(27)20-18(14)22(23,21(29-20)19(15)25-12)6-7-26(17)11-13-2-3-13/h4-5,10,13,17,21,27-28H,2-3,6-9,11H2,1H3/t17-,21+,22+,23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Binding affinity for Opioid receptor mu 1 was determined by inhibition of binding of [3H]DAMGO (1.4-3 nM) to rat brain membranes				J Med Chem 42: 3527-38 (1999) Article DOI: 10.1021/jm990039i BindingDB Entry DOI: 10.7270/Q2QR4XSQ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50123274 (6-amino(imino)methylamino-19-cyclopropylmethyl-11-...) Show SMILES [#7]\[#6](-[#7])=[#7]/c1cnc2-[#6@@H]3-[#8]-c4c5c(-[#6]-[#6@H]6-[#7](-[#6]-[#6]-7-[#6]-[#6]-7)-[#6]-[#6][C@@]35[C@@]6([#8])[#6]-c2c1)ccc4-[#8] Show InChI InChI=1S/C24H27N5O3/c25-22(26)28-15-7-14-9-24(31)17-8-13-3-4-16(30)20-18(13)23(24,21(32-20)19(14)27-10-15)5-6-29(17)11-12-1-2-12/h3-4,7,10,12,17,21,30-31H,1-2,5-6,8-9,11H2,(H4,25,26,28)/t17-,21+,23+,24-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Antagonist activity on agonist stimulated [35S]GTP-gamma-S, binding in guinea pig caudate membranes (10 uM DAMGO as the agonist ligand for Mu-recepto...				Bioorg Med Chem Lett 13: 529-32 (2003) BindingDB Entry DOI: 10.7270/Q27S7P9P
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50001173 (CHEMBL2112572) Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)Cc1cncnc21)ccc3O |THB:10:9:17:4.5.6| Show InChI InChI=1S/C22H23N3O3/c26-15-4-3-13-7-16-22(27)8-14-9-23-11-24-18(14)20-21(22,17(13)19(15)28-20)5-6-25(16)10-12-1-2-12/h3-4,9,11-12,16,20,26-27H,1-2,5-8,10H2/t16-,20+,21+,22-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Binding affinity for Opioid receptor kappa 1 was determined by inhibition of binding of [3H]U-69593 (1.2-2.2 nM) to guinea pig brain membranes				J Med Chem 42: 3527-38 (1999) Article DOI: 10.1021/jm990039i BindingDB Entry DOI: 10.7270/Q2QR4XSQ
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50123274 (6-amino(imino)methylamino-19-cyclopropylmethyl-11-...) Show SMILES [#7]\[#6](-[#7])=[#7]/c1cnc2-[#6@@H]3-[#8]-c4c5c(-[#6]-[#6@H]6-[#7](-[#6]-[#6]-7-[#6]-[#6]-7)-[#6]-[#6][C@@]35[C@@]6([#8])[#6]-c2c1)ccc4-[#8] Show InChI InChI=1S/C24H27N5O3/c25-22(26)28-15-7-14-9-24(31)17-8-13-3-4-16(30)20-18(13)23(24,21(32-20)19(14)27-10-15)5-6-29(17)11-12-1-2-12/h3-4,7,10,12,17,21,30-31H,1-2,5-6,8-9,11H2,(H4,25,26,28)/t17-,21+,23+,24-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Antagonist activity on agonist stimulated [35S]GTP-gamma-S, binding in guinea pig caudate membranes (10 uM SNC-80 as the agonist ligand for delta-rec...				Bioorg Med Chem Lett 13: 529-32 (2003) BindingDB Entry DOI: 10.7270/Q27S7P9P
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50123275 (19-cyclopropylmethyl-6-benzylamino-11-oxa-8,19-dia...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncc(NCc2ccccc2)cc1C[C@@]35O Show InChI InChI=1S/C30H31N3O3/c34-23-9-8-20-13-24-30(35)14-21-12-22(31-15-18-4-2-1-3-5-18)16-32-26(21)28-29(30,25(20)27(23)36-28)10-11-33(24)17-19-6-7-19/h1-5,8-9,12,16,19,24,28,31,34-35H,6-7,10-11,13-15,17H2/t24-,28+,29+,30-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Binding affinity for kappa opioid receptor was measured using [3H]U-69593				Bioorg Med Chem Lett 13: 529-32 (2003) BindingDB Entry DOI: 10.7270/Q27S7P9P
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM60212 ((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O Show InChI InChI=1S/C20H23NO4/c22-13-4-3-12-9-15-20(24)6-5-14(23)18-19(20,16(12)17(13)25-18)7-8-21(15)10-11-1-2-11/h3-4,11,15,18,22,24H,1-2,5-10H2/t15-,18+,19+,20-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Binding affinity for Opioid receptor kappa 1 was determined by inhibition of binding of [3H]U-69593 (1.2-2.2 nM) to guinea pig brain membranes				J Med Chem 42: 3527-38 (1999) Article DOI: 10.1021/jm990039i BindingDB Entry DOI: 10.7270/Q2QR4XSQ
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50123276 (19-cyclopropylmethyl-6-amino-11-oxa-8,19-diazahexa...) Show SMILES Nc1cnc2[C@@H]3Oc4c5c(C[C@H]6N(CC7CC7)CC[C@@]35[C@@]6(O)Cc2c1)ccc4O Show InChI InChI=1S/C23H25N3O3/c24-15-7-14-9-23(28)17-8-13-3-4-16(27)20-18(13)22(23,21(29-20)19(14)25-10-15)5-6-26(17)11-12-1-2-12/h3-4,7,10,12,17,21,27-28H,1-2,5-6,8-9,11,24H2/t17-,21+,22+,23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Binding affinity to delta opioid receptor was measured using [3H]DADLE				Bioorg Med Chem Lett 13: 529-32 (2003) BindingDB Entry DOI: 10.7270/Q27S7P9P
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50123273 (19-cyclopropylmethyl-(2S,10R)-11-oxa-8,19-diazahex...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncccc1C[C@@]35O Show InChI InChI=1S/C23H24N2O3/c26-16-6-5-14-10-17-23(27)11-15-2-1-8-24-19(15)21-22(23,18(14)20(16)28-21)7-9-25(17)12-13-3-4-13/h1-2,5-6,8,13,17,21,26-27H,3-4,7,9-12H2/t17-,21+,22+,23-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Binding affinity for kappa opioid receptor was measured using [3H]U-69593				Bioorg Med Chem Lett 13: 529-32 (2003) BindingDB Entry DOI: 10.7270/Q27S7P9P
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50123279 (19-cyclopropylmethyl-6-(1H-1-pyrrolyl)-11-oxa-8,19...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncc(cc1C[C@@]35O)-n1cccc1 Show InChI InChI=1S/C27H27N3O3/c31-20-6-5-17-12-21-27(32)13-18-11-19(29-8-1-2-9-29)14-28-23(18)25-26(27,22(17)24(20)33-25)7-10-30(21)15-16-3-4-16/h1-2,5-6,8-9,11,14,16,21,25,31-32H,3-4,7,10,12-13,15H2/t21-,25+,26+,27-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Antagonist activity on agonist stimulated [35S]GTP-gamma-S, binding in guinea pig caudate membranes (10 uM U69,593 as the agonist ligand for kappa-re...				Bioorg Med Chem Lett 13: 529-32 (2003) BindingDB Entry DOI: 10.7270/Q27S7P9P
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50123273 (19-cyclopropylmethyl-(2S,10R)-11-oxa-8,19-diazahex...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncccc1C[C@@]35O Show InChI InChI=1S/C23H24N2O3/c26-16-6-5-14-10-17-23(27)11-15-2-1-8-24-19(15)21-22(23,18(14)20(16)28-21)7-9-25(17)12-13-3-4-13/h1-2,5-6,8,13,17,21,26-27H,3-4,7,9-12H2/t17-,21+,22+,23-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Binding affinity for Opioid receptor kappa 1 was determined by inhibition of binding of [3H]U-69593 (1.2-2.2 nM) to guinea pig brain membranes				J Med Chem 42: 3527-38 (1999) Article DOI: 10.1021/jm990039i BindingDB Entry DOI: 10.7270/Q2QR4XSQ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50123272 (CHEMBL357680 | ethyl 19-cyclopropylmethyl-2,13-dih...) Show SMILES CCOC(=O)c1cnc2[C@@H]3Oc4c5c(C[C@H]6N(CC7CC7)CC[C@@]35[C@@]6(O)Cc2c1)ccc4O Show InChI InChI=1S/C26H28N2O5/c1-2-32-24(30)17-9-16-11-26(31)19-10-15-5-6-18(29)22-20(15)25(26,23(33-22)21(16)27-12-17)7-8-28(19)13-14-3-4-14/h5-6,9,12,14,19,23,29,31H,2-4,7-8,10-11,13H2,1H3/t19-,23+,25+,26-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Binding affinity for kappa opioid receptor was measured using [3H]U-69593				Bioorg Med Chem Lett 13: 529-32 (2003) BindingDB Entry DOI: 10.7270/Q27S7P9P
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM82551 (C18130 | CAS_105618-26-6 | NOR-BNI (HCI)2 | NORBNI) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2[C@@H]4Oc6c7c(C[C@H]8N(CC9CC9)CC[C@@]47[C@@]8(O)Cc2c1C[C@@]35O)ccc6O |r| Show InChI InChI=1S/C40H43N3O6/c44-25-7-5-21-13-27-39(46)15-23-24-16-40(47)28-14-22-6-8-26(45)34-30(22)38(40,10-12-43(28)18-20-3-4-20)36(49-34)32(24)41-31(23)35-37(39,29(21)33(25)48-35)9-11-42(27)17-19-1-2-19/h5-8,19-20,27-28,35-36,41,44-47H,1-4,9-18H2/t27-,28-,35+,36+,37+,38+,39-,40-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Antagonist activity on agonist stimulated [35S]GTP-gamma-S, binding in guinea pig caudate membranes (10 uM SNC-80 as the agonist ligand for delta-rec...				Bioorg Med Chem Lett 13: 529-32 (2003) BindingDB Entry DOI: 10.7270/Q27S7P9P
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50001190 (CHEMBL2112576) Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)Cc1ccc(nc21)-c1ccccc1)ccc3O |THB:10:9:17:4.5.6| Show InChI InChI=1S/C29H28N2O3/c32-22-11-9-19-14-23-29(33)15-20-8-10-21(18-4-2-1-3-5-18)30-25(20)27-28(29,24(19)26(22)34-27)12-13-31(23)16-17-6-7-17/h1-5,8-11,17,23,27,32-33H,6-7,12-16H2/t23-,27+,28+,29-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Binding affinity for Opioid receptor mu 1 was determined by inhibition of binding of [3H]DAMGO (1.4-3 nM) to rat brain membranes				J Med Chem 42: 3527-38 (1999) Article DOI: 10.1021/jm990039i BindingDB Entry DOI: 10.7270/Q2QR4XSQ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50001188 (CHEMBL2112571) Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)Cc1cnc(nc21)-c1ccccc1)ccc3O |THB:10:9:17:4.5.6| Show InChI InChI=1S/C28H27N3O3/c32-20-9-8-18-12-21-28(33)13-19-14-29-26(17-4-2-1-3-5-17)30-23(19)25-27(28,22(18)24(20)34-25)10-11-31(21)15-16-6-7-16/h1-5,8-9,14,16,21,25,32-33H,6-7,10-13,15H2/t21-,25+,27+,28-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Binding affinity for Opioid receptor kappa 1 was determined by inhibition of binding of [3H]U-69593 (1.2-2.2 nM) to guinea pig brain membranes				J Med Chem 42: 3527-38 (1999) Article DOI: 10.1021/jm990039i BindingDB Entry DOI: 10.7270/Q2QR4XSQ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50123279 (19-cyclopropylmethyl-6-(1H-1-pyrrolyl)-11-oxa-8,19...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncc(cc1C[C@@]35O)-n1cccc1 Show InChI InChI=1S/C27H27N3O3/c31-20-6-5-17-12-21-27(32)13-18-11-19(29-8-1-2-9-29)14-28-23(18)25-26(27,22(17)24(20)33-25)7-10-30(21)15-16-3-4-16/h1-2,5-6,8-9,11,14,16,21,25,31-32H,3-4,7,10,12-13,15H2/t21-,25+,26+,27-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Binding affinity for kappa opioid receptor was measured using [3H]U-69593				Bioorg Med Chem Lett 13: 529-32 (2003) BindingDB Entry DOI: 10.7270/Q27S7P9P
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50123276 (19-cyclopropylmethyl-6-amino-11-oxa-8,19-diazahexa...) Show SMILES Nc1cnc2[C@@H]3Oc4c5c(C[C@H]6N(CC7CC7)CC[C@@]35[C@@]6(O)Cc2c1)ccc4O Show InChI InChI=1S/C23H25N3O3/c24-15-7-14-9-23(28)17-8-13-3-4-16(27)20-18(13)22(23,21(29-20)19(14)25-10-15)5-6-26(17)11-12-1-2-12/h3-4,7,10,12,17,21,27-28H,1-2,5-6,8-9,11,24H2/t17-,21+,22+,23-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Binding affinity for kappa opioid receptor was measured using [3H]U-69593				Bioorg Med Chem Lett 13: 529-32 (2003) BindingDB Entry DOI: 10.7270/Q27S7P9P
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50123276 (19-cyclopropylmethyl-6-amino-11-oxa-8,19-diazahexa...) Show SMILES Nc1cnc2[C@@H]3Oc4c5c(C[C@H]6N(CC7CC7)CC[C@@]35[C@@]6(O)Cc2c1)ccc4O Show InChI InChI=1S/C23H25N3O3/c24-15-7-14-9-23(28)17-8-13-3-4-16(27)20-18(13)22(23,21(29-20)19(14)25-10-15)5-6-26(17)11-12-1-2-12/h3-4,7,10,12,17,21,27-28H,1-2,5-6,8-9,11,24H2/t17-,21+,22+,23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Binding affinity to mu opioid receptor was measured using [3H]DAMGO				Bioorg Med Chem Lett 13: 529-32 (2003) BindingDB Entry DOI: 10.7270/Q27S7P9P
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50001196 (CHEMBL610522) Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)Cc1cc(cnc21)-c1ccccc1)ccc3O |r,THB:10:9:17:4.5.6| Show InChI InChI=1S/C29H28N2O3/c32-22-9-8-19-13-23-29(33)14-20-12-21(18-4-2-1-3-5-18)15-30-25(20)27-28(29,24(19)26(22)34-27)10-11-31(23)16-17-6-7-17/h1-5,8-9,12,15,17,23,27,32-33H,6-7,10-11,13-14,16H2/t23-,27+,28+,29-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Binding affinity for Opioid receptor mu 1 was determined by inhibition of binding of [3H]DAMGO (1.4-3 nM) to rat brain membranes				J Med Chem 42: 3527-38 (1999) Article DOI: 10.1021/jm990039i BindingDB Entry DOI: 10.7270/Q2QR4XSQ
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM82551 (C18130 | CAS_105618-26-6 | NOR-BNI (HCI)2 | NORBNI) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2[C@@H]4Oc6c7c(C[C@H]8N(CC9CC9)CC[C@@]47[C@@]8(O)Cc2c1C[C@@]35O)ccc6O |r| Show InChI InChI=1S/C40H43N3O6/c44-25-7-5-21-13-27-39(46)15-23-24-16-40(47)28-14-22-6-8-26(45)34-30(22)38(40,10-12-43(28)18-20-3-4-20)36(49-34)32(24)41-31(23)35-37(39,29(21)33(25)48-35)9-11-42(27)17-19-1-2-19/h5-8,19-20,27-28,35-36,41,44-47H,1-4,9-18H2/t27-,28-,35+,36+,37+,38+,39-,40-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Antagonist activity on agonist stimulated [35S]GTP-gamma-S, binding in guinea pig caudate membranes (10 uM DAMGO as the agonist ligand for mu-recepto...				Bioorg Med Chem Lett 13: 529-32 (2003) BindingDB Entry DOI: 10.7270/Q27S7P9P
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50123275 (19-cyclopropylmethyl-6-benzylamino-11-oxa-8,19-dia...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncc(NCc2ccccc2)cc1C[C@@]35O Show InChI InChI=1S/C30H31N3O3/c34-23-9-8-20-13-24-30(35)14-21-12-22(31-15-18-4-2-1-3-5-18)16-32-26(21)28-29(30,25(20)27(23)36-28)10-11-33(24)17-19-6-7-19/h1-5,8-9,12,16,19,24,28,31,34-35H,6-7,10-11,13-15,17H2/t24-,28+,29+,30-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Binding affinity to mu opioid receptor was measured using [3H]DAMGO				Bioorg Med Chem Lett 13: 529-32 (2003) BindingDB Entry DOI: 10.7270/Q27S7P9P
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50123271 (19-cyclopropylmethyl-6-bromo-11-oxa-8,19-diazahexa...) Show SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncc(Br)cc1C[C@@]35O Show InChI InChI=1S/C23H23BrN2O3/c24-15-7-14-9-23(28)17-8-13-3-4-16(27)20-18(13)22(23,21(29-20)19(14)25-10-15)5-6-26(17)11-12-1-2-12/h3-4,7,10,12,17,21,27-28H,1-2,5-6,8-9,11H2/t17-,21+,22+,23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Binding affinity to mu opioid receptor was measured using [3H]DAMGO				Bioorg Med Chem Lett 13: 529-32 (2003) BindingDB Entry DOI: 10.7270/Q27S7P9P
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 169 total )  |  Next  |  Last  >>

Jump to: