BindingDB PrimarySearch

Found 44 hits Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM82551'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	PubMed	0.390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Displacement of [3H]- diprenorphine from mu-W318A-receptor expressed in HEK 293 cells				J Med Chem 44: 857-62 (2001) BindingDB Entry DOI: 10.7270/Q27H1K9D
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	PubMed	0.390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Displacement of [3H]- diprenorphine from mu-W318A-receptor expressed in HEK 293 cells				J Med Chem 44: 857-62 (2001) BindingDB Entry DOI: 10.7270/Q27H1K9D
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	PubMed	0.940	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity using [3H]diprenorphine as the radioligand against K303E Opioid receptor mu 1 in COS-7 cells				J Med Chem 43: 1573-6 (2000) BindingDB Entry DOI: 10.7270/Q2FF3T23
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description Inhibition of [3H]diprenorphine binding to rat Opioid receptor mu 1 expressed in C6 cells				J Med Chem 48: 1676-9 (2005) Article DOI: 10.1021/jm049172n BindingDB Entry DOI: 10.7270/Q2DB84N0
University of Bath Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by PDSP K_i Database									Mol Pharmacol 45: 330-4 (1994) Article DOI: 10.1016/j.bioorg.2015.02.008 BindingDB Entry DOI: 10.7270/Q21Z42X1
University of Pennsylvania Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rensselaer Polytechnic Institute Curated by ChEMBL					Assay Description Activity at human cloned mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assay				Bioorg Med Chem Lett 19: 203-8 (2008) Article DOI: 10.1016/j.bmcl.2008.10.134 BindingDB Entry DOI: 10.7270/Q2RX9D1K
Rensselaer Polytechnic Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	PubMed	8.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by PDSP K_i Database									NIDA Res Monogr 178: 440-66 (1998) BindingDB Entry DOI: 10.7270/Q23J3BH2
SRI International Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Antagonist activity on agonist stimulated [35S]GTP-gamma-S, binding in guinea pig caudate membranes (10 uM DAMGO as the agonist ligand for mu-recepto...				Bioorg Med Chem Lett 13: 529-32 (2003) BindingDB Entry DOI: 10.7270/Q27S7P9P
Southern Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Antagonist activity on agonist (DAMGO) stimulated [35S]GTP-gamma-S, binding in cloned mu opioid receptors				J Med Chem 44: 2687-90 (2001) BindingDB Entry DOI: 10.7270/Q25T3M58
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description inhibition of stimulation of [35S]GTP-gamma-S, binding produced by the selective agonist (DAMGO, mu-receptor), in guinea pig caudate membranes				J Med Chem 44: 2687-90 (2001) BindingDB Entry DOI: 10.7270/Q25T3M58
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [35S]GTP-gamma-S, binding from Opioid receptor mu 1 in Guinea pig Caudate stimulated by DAMGO				J Med Chem 41: 5188-97 (1999) Article DOI: 10.1021/jm980511k BindingDB Entry DOI: 10.7270/Q2P26ZT4
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Compound was evaluated for its binding affinity by displacing DAMGO to human cloned mu opioid receptor transfected into CHO cells using [35S]GTP-gamm...				Bioorg Med Chem Lett 10: 2259-61 (2001) BindingDB Entry DOI: 10.7270/Q2WS8TRF
University of Bristol Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from human recombinant mu opioid receptor expressed in CHO cell membranes after 60 mins by scintillation counting method				Bioorg Med Chem 22: 4067-72 (2014) Article DOI: 10.1016/j.bmc.2014.05.065 BindingDB Entry DOI: 10.7270/Q2JM2C8P
University of Bath Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from human recombinant Opioid receptor mu 1 on CHO cell membranes.				J Med Chem 46: 1563-6 (2003) Article DOI: 10.1021/jm021073r BindingDB Entry DOI: 10.7270/Q27945F9
University of Bath Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description Ability to displace [3H]DAMGO from human recombinant Opioid receptor mu 1 in CHO cells				J Med Chem 46: 314-7 (2003) Article DOI: 10.1021/jm020997b BindingDB Entry DOI: 10.7270/Q2PK0GW4
University of Bath Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description Binding affinity against cloned human Opioid receptor mu 1 transfected into chinese hamster ovary cells using [3H]DAMGO as radioligand				J Med Chem 46: 5505-11 (2003) Article DOI: 10.1021/jm0309203 BindingDB Entry DOI: 10.7270/Q2V69K9X
University of Bath Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity towards human cloned Opioid receptor mu 1 using [3H]DAMGO				J Med Chem 46: 3127-37 (2003) Article DOI: 10.1021/jm030094y BindingDB Entry DOI: 10.7270/Q2319WM4
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description Inhibition of [3H]DAMGO binding to human Mu opioid receptor expressed in CHO cells				J Med Chem 47: 5069-75 (2004) Article DOI: 10.1021/jm040807s BindingDB Entry DOI: 10.7270/Q2S46SQB
University of Bath Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Compound was evaluated for its binding affinity to CHO cells expressing cloned human Opioid receptor mu 1 by displacing [3H]-DAMGO				Bioorg Med Chem Lett 10: 2259-61 (2001) BindingDB Entry DOI: 10.7270/Q2WS8TRF
University of Bristol Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by PDSP K_i Database									NIDA Res Monogr 178: 440-66 (1998) BindingDB Entry DOI: 10.7270/Q23J3BH2
SRI International Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	28.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kitasato University Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor in guinea pig forebrain				Bioorg Med Chem Lett 20: 5035-8 (2010) Article DOI: 10.1016/j.bmcl.2010.07.035 BindingDB Entry DOI: 10.7270/Q2CJ8DPH
Kitasato University Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	28.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kitasato University Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor in guinea pig forebrain				Bioorg Med Chem 19: 1205-21 (2011) Article DOI: 10.1016/j.bmc.2010.12.035 BindingDB Entry DOI: 10.7270/Q23N23P2
Kitasato University Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	PubMed	28.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Clinical Research Institute of Montreal Curated by ChEMBL					Assay Description Binding affinity was measured on mu opioid receptor				J Med Chem 44: 3048-53 (2001) BindingDB Entry DOI: 10.7270/Q28K79SN
Clinical Research Institute of Montreal Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human opioid mu receptor expressed in CHO cells after 120 mins by scintillation counting				J Med Chem 54: 8000-12 (2011) Article DOI: 10.1021/jm200789r BindingDB Entry DOI: 10.7270/Q29C6XVV
Lilly Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity of compound was measured against Opioid receptor mu 1 on electrically stimulated guinea pig ileal longitudinal muscle myenteric plex...				J Med Chem 34: 1292-6 (1991) BindingDB Entry DOI: 10.7270/Q2C53MF5
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description The binding affinity against mu-opioid receptor using [3H]- DAMGO as radioligand				J Med Chem 37: 1495-500 (1994) BindingDB Entry DOI: 10.7270/Q2XP75K7
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity determined on Opioid receptor mu 1 in Guinea pig brain membranes using radioligand [3H]DAMGO				J Med Chem 41: 5188-97 (1999) Article DOI: 10.1021/jm980511k BindingDB Entry DOI: 10.7270/Q2P26ZT4
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity for mu opioid receptor was determined using radioligand [3H][D-Ala2,MePhe4,Gly-ol6]enkephalin (DAMGO) in Guinea pig brain membranes.				J Med Chem 36: 179-80 (1993) BindingDB Entry DOI: 10.7270/Q2Z60PPM
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	PubMed	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Binding affinity towards cloned human Opioid receptor mu 1 in CHO cell membranes.				J Med Chem 43: 2698-702 (2000) BindingDB Entry DOI: 10.7270/Q25D8SJ1
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	PubMed	56.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Displacement of [3H]- diprenorphine from mu-receptor expressed in HEK 293 cells				J Med Chem 44: 857-62 (2001) BindingDB Entry DOI: 10.7270/Q27H1K9D
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	PubMed	65	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity to mu-opioid receptor of rat brain using [3H]DAMGO as radioligand				J Med Chem 44: 2687-90 (2001) BindingDB Entry DOI: 10.7270/Q25T3M58
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	PubMed	65	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Ability to displace [3H]DAMGO from Opioid receptor mu 1 of rat brain				J Med Chem 45: 3524-30 (2002) BindingDB Entry DOI: 10.7270/Q2959J8R
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	65	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Binding affinity of compound for Opioid receptor mu 1 was determined using [3H]DAMGO as radioligand from rat brain tissue				J Med Chem 47: 1070-3 (2004) Article DOI: 10.1021/jm030467v BindingDB Entry DOI: 10.7270/Q2BV7HC4
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	65	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]DAMGO binding to Opioid receptor mu 1 of rat brain tissue				J Med Chem 46: 3127-37 (2003) Article DOI: 10.1021/jm030094y BindingDB Entry DOI: 10.7270/Q2319WM4
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity using [3H]diprenorphine as the radioligand against wild-type Opioid receptor mu 1 in COS-7 cells				J Med Chem 43: 1573-6 (2000) BindingDB Entry DOI: 10.7270/Q2FF3T23
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description In vitro binding affinity to human Opioid receptor mu 1 on CHO cell membranes using [3H]diprenorphine displacement.				J Med Chem 46: 2104-9 (2003) Article DOI: 10.1021/jm020125+ BindingDB Entry DOI: 10.7270/Q2NZ88CF
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cells after 1 hr by liquid scintillation counting				J Med Chem 54: 5868-77 (2011) Article DOI: 10.1021/jm2006035 BindingDB Entry DOI: 10.7270/Q2X63NBJ
Pfizer Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	102	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Effect on binding affinity of mutational exchange of Lys303 in the Opioid receptor mu 1 in transiently expressed rat cos-7 cells activity expressed a...				J Med Chem 41: 4911-4 (1999) Article DOI: 10.1021/jm9805182 BindingDB Entry DOI: 10.7270/Q2K9387K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.30	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibitory activity against mu-opioid receptor in guinea pig ileum longitudinal muscle using morphine				J Med Chem 36: 2412-5 (1993) BindingDB Entry DOI: 10.7270/Q2MP53WW
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
University of Washington Curated by ChEMBL					Assay Description Inhibition of opioid receptor mu by displacing 1 nM [3H]DAGO in guinea pig brain membrane				J Med Chem 35: 4589-94 (1993) BindingDB Entry DOI: 10.7270/Q27S7PCK
University of Washington Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	212	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at human mu opioid receptor assessed as inhibition of DAMGO-stimulated [35S]GTPgammaS binding				Bioorg Med Chem Lett 20: 5847-52 (2010) Article DOI: 10.1016/j.bmcl.2010.07.113 BindingDB Entry DOI: 10.7270/Q23F4PV1
AstraZeneca Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	212	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at human mu opioid receptor expressed in HEK cells assessed as inhibition of DAMGO-induced [35S]GTPgammaS binding				Bioorg Med Chem Lett 20: 5405-10 (2010) Article DOI: 10.1016/j.bmcl.2010.07.112 BindingDB Entry DOI: 10.7270/Q2X92BHQ
AstraZeneca Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	120	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Agonist activity at human recombinant mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assay				J Med Chem 53: 5290-301 (2010) Article DOI: 10.1021/jm1004978 BindingDB Entry DOI: 10.7270/Q2K35VNP
Research Triangle Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM82551 (C18130 \| CAS_105618-26-6 \| NOR-BNI (HCI)2 \| NORBNI) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a
University of Bath Curated by ChEMBL					Assay Description Stimulation of DAMGO binding in recombinant human Opioid receptor mu 1 transfected into CHO cells				J Med Chem 46: 1563-6 (2003) Article DOI: 10.1021/jm021073r BindingDB Entry DOI: 10.7270/Q27945F9
University of Bath Curated by ChEMBL					More data for this Ligand-Target Pair