Compile Data Set for Download or QSAR

Found 114 hits with Last Name = 'kubrak' and Initial = 'd'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50242184 (Scalaradial) Show SMILES [H][C@@]12CC[C@@]3(C)[C@]4([H])CC=C(C=O)[C@H](C=O)[C@@]4(C)[C@H](C[C@]3([H])[C@@]1(C)CCCC2(C)C)OC(C)=O |r,t:9| Show InChI InChI=1S/C27H40O4/c1-17(30)31-23-14-22-25(4)12-7-11-24(2,3)20(25)10-13-26(22,5)21-9-8-18(15-28)19(16-29)27(21,23)6/h8,15-16,19-23H,7,9-14H2,1-6H3/t19-,20-,21-,22+,23-,25-,26-,27+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against human synovial fluid phospholipase A2 (HSF-PLA2) by monitoring hydrolysis of [3H]-arachidonic acid labeled E. co...				Bioorg Med Chem Lett 4: 1873-1878 (1994) Article DOI: 10.1016/S0960-894X(01)80388-7 BindingDB Entry DOI: 10.7270/Q2SB45PR
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50016627 (C,C,C-Trifluoro-N-[7-(quinolin-2-ylmethoxy)-naphth...) Show SMILES FC(F)(F)S(=O)(=O)Nc1ccc2ccc(OCc3ccc4ccccc4n3)cc2c1 Show InChI InChI=1S/C21H15F3N2O3S/c22-21(23,24)30(27,28)26-17-8-5-14-7-10-19(12-16(14)11-17)29-13-18-9-6-15-3-1-2-4-20(15)25-18/h1-12,26H,13H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibitory concentration of the compound to inhibit 5-lipoxygenase in the rat				J Med Chem 32: 1176-83 (1989) BindingDB Entry DOI: 10.7270/Q2833R1T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50012434 ((REV-5,901)1-[3-(Quinolin-2-ylmethoxy)-phenyl]-hex...) Show SMILES CCCCCC(O)c1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C22H25NO2/c1-2-3-4-12-22(24)18-9-7-10-20(15-18)25-16-19-14-13-17-8-5-6-11-21(17)23-19/h5-11,13-15,22,24H,2-4,12,16H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Laboratories Curated by ChEMBL					Assay Description Ability to inhibit 5-lipoxygenase in guinea pig				J Med Chem 30: 2087-93 (1987) BindingDB Entry DOI: 10.7270/Q2FQ9VMQ
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50012434 ((REV-5,901)1-[3-(Quinolin-2-ylmethoxy)-phenyl]-hex...) Show SMILES CCCCCC(O)c1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C22H25NO2/c1-2-3-4-12-22(24)18-9-7-10-20(15-18)25-16-19-14-13-17-8-5-6-11-21(17)23-19/h5-11,13-15,22,24H,2-4,12,16H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat polymorphonuclear leukocyte (PMN) 5-Lipoxygenase in vitro				J Med Chem 29: 1429-35 (1986) BindingDB Entry DOI: 10.7270/Q2GX49K4
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50012434 ((REV-5,901)1-[3-(Quinolin-2-ylmethoxy)-phenyl]-hex...) Show SMILES CCCCCC(O)c1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C22H25NO2/c1-2-3-4-12-22(24)18-9-7-10-20(15-18)25-16-19-14-13-17-8-5-6-11-21(17)23-19/h5-11,13-15,22,24H,2-4,12,16H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit Lipoxygenase in vitro was determined				J Med Chem 30: 400-5 (1987) BindingDB Entry DOI: 10.7270/Q2K936JS
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50025771 (CHEMBL338408 | N-[3-(Benzothiazol-2-ylmethoxy)-phe...) Show SMILES COC(=O)CCC(=O)N(O)c1cccc(OCc2nc3ccccc3s2)c1 Show InChI InChI=1S/C19H18N2O5S/c1-25-19(23)10-9-18(22)21(24)13-5-4-6-14(11-13)26-12-17-20-15-7-2-3-8-16(15)27-17/h2-8,11,24H,9-10,12H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit Lipoxygenase in vitro was determined				J Med Chem 30: 400-5 (1987) BindingDB Entry DOI: 10.7270/Q2K936JS
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50022203 (CHEMBL33734 | N-Hydroxy-N-[3-(naphthalen-2-ylmetho...) Show SMILES COC(=O)CCC(=O)N(O)c1cccc(OCc2ccc3ccccc3c2)c1 Show InChI InChI=1S/C22H21NO5/c1-27-22(25)12-11-21(24)23(26)19-7-4-8-20(14-19)28-15-16-9-10-17-5-2-3-6-18(17)13-16/h2-10,13-14,26H,11-12,15H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat polymorphonuclear leukocyte (PMN) 5-Lipoxygenase in vitro				J Med Chem 29: 1429-35 (1986) BindingDB Entry DOI: 10.7270/Q2GX49K4
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50022202 (CHEMBL284706 | N-Hydroxy-N-[3-(naphthalen-2-yloxym...) Show SMILES COC(=O)CCC(=O)N(O)c1cccc(COc2ccc3ccccc3c2)c1 Show InChI InChI=1S/C22H21NO5/c1-27-22(25)12-11-21(24)23(26)19-8-4-5-16(13-19)15-28-20-10-9-17-6-2-3-7-18(17)14-20/h2-10,13-14,26H,11-12,15H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat polymorphonuclear leukocyte (PMN) 5-Lipoxygenase in vitro				J Med Chem 29: 1429-35 (1986) BindingDB Entry DOI: 10.7270/Q2GX49K4
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50006801 (CHEMBL287012 | N-Hydroxy-N-[3-(quinolin-2-ylmethox...) Show SMILES COC(=O)CCC(=O)N(O)c1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C21H20N2O5/c1-27-21(25)12-11-20(24)23(26)17-6-4-7-18(13-17)28-14-16-10-9-15-5-2-3-8-19(15)22-16/h2-10,13,26H,11-12,14H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Concentration that produces 50% inhibition of A-23,187-stimulated radiolabelled 5-HETE and TXB2 synthesis by PMN 5-lipoxygenase.				J Med Chem 33: 240-5 (1990) BindingDB Entry DOI: 10.7270/Q24Q7T0P
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50006801 (CHEMBL287012 | N-Hydroxy-N-[3-(quinolin-2-ylmethox...) Show SMILES COC(=O)CCC(=O)N(O)c1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C21H20N2O5/c1-27-21(25)12-11-20(24)23(26)17-6-4-7-18(13-17)28-14-16-10-9-15-5-2-3-8-19(15)22-16/h2-10,13,26H,11-12,14H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit Lipoxygenase in vitro was determined				J Med Chem 30: 400-5 (1987) BindingDB Entry DOI: 10.7270/Q2K936JS
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50006801 (CHEMBL287012 | N-Hydroxy-N-[3-(quinolin-2-ylmethox...) Show SMILES COC(=O)CCC(=O)N(O)c1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C21H20N2O5/c1-27-21(25)12-11-20(24)23(26)17-6-4-7-18(13-17)28-14-16-10-9-15-5-2-3-8-19(15)22-16/h2-10,13,26H,11-12,14H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat polymorphonuclear leukocyte (PMN) 5-Lipoxygenase in vitro				J Med Chem 29: 1429-35 (1986) BindingDB Entry DOI: 10.7270/Q2GX49K4
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50022193 (CHEMBL285175 | N-[3-(Naphthalen-2-yloxymethyl)-phe...) Show SMILES COC(=O)CCC(=O)Nc1cccc(COc2ccc3ccccc3c2)c1 Show InChI InChI=1S/C22H21NO4/c1-26-22(25)12-11-21(24)23-19-8-4-5-16(13-19)15-27-20-10-9-17-6-2-3-7-18(17)14-20/h2-10,13-14H,11-12,15H2,1H3,(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.91E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat polymorphonuclear leukocyte (PMN) 5-Lipoxygenase in vitro				J Med Chem 29: 1429-35 (1986) BindingDB Entry DOI: 10.7270/Q2GX49K4
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50006806 (C,C,C-Trifluoro-N-[3-(quinolin-2-ylmethoxy)-phenyl...) Show SMILES FC(F)(F)S(=O)(=O)Nc1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C17H13F3N2O3S/c18-17(19,20)26(23,24)22-13-5-3-6-15(10-13)25-11-14-9-8-12-4-1-2-7-16(12)21-14/h1-10,22H,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Concentration for 50% inhibition of A-23,187-stimulated radiolabelled 5-HETE and TXB2 synthesis by PMN 5-lipoxygenase				J Med Chem 33: 240-5 (1990) BindingDB Entry DOI: 10.7270/Q24Q7T0P
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50006822 (1,1-Diethyl-3-{2-hydroxy-2-[3-(quinolin-2-ylmethox...) Show SMILES CCN(CC)C(=O)N(C)C[C@H](O)c1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C24H29N3O3/c1-4-27(5-2)24(29)26(3)16-23(28)19-10-8-11-21(15-19)30-17-20-14-13-18-9-6-7-12-22(18)25-20/h6-15,23,28H,4-5,16-17H2,1-3H3/t23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Laboratories Curated by ChEMBL					Assay Description Ability to inhibit 5-lipoxygenase in guinea pig				J Med Chem 30: 2087-93 (1987) BindingDB Entry DOI: 10.7270/Q2FQ9VMQ
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50022205 (CHEMBL34106 | N-[4-(Quinolin-2-ylmethoxy)-phenyl]-...) Show SMILES COC(=O)CCC(=O)Nc1ccc(OCc2ccc3ccccc3n2)cc1 Show InChI InChI=1S/C21H20N2O4/c1-26-21(25)13-12-20(24)23-16-8-10-18(11-9-16)27-14-17-7-6-15-4-2-3-5-19(15)22-17/h2-11H,12-14H2,1H3,(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat polymorphonuclear leukocyte (PMN) 5-Lipoxygenase in vitro				J Med Chem 29: 1429-35 (1986) BindingDB Entry DOI: 10.7270/Q2GX49K4
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50022210 (CHEMBL289901 | N-[3-(Naphthalen-2-ylmethoxy)-pheny...) Show SMILES COC(=O)CCC(=O)Nc1cccc(OCc2ccc3ccccc3c2)c1 Show InChI InChI=1S/C22H21NO4/c1-26-22(25)12-11-21(24)23-19-7-4-8-20(14-19)27-15-16-9-10-17-5-2-3-6-18(17)13-16/h2-10,13-14H,11-12,15H2,1H3,(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat polymorphonuclear leukocyte (PMN) 5-Lipoxygenase in vitro				J Med Chem 29: 1429-35 (1986) BindingDB Entry DOI: 10.7270/Q2GX49K4
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50006806 (C,C,C-Trifluoro-N-[3-(quinolin-2-ylmethoxy)-phenyl...) Show SMILES FC(F)(F)S(=O)(=O)Nc1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C17H13F3N2O3S/c18-17(19,20)26(23,24)22-13-5-3-6-15(10-13)25-11-14-9-8-12-4-1-2-7-16(12)21-14/h1-10,22H,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibitory concentration to inhibit Prostaglandin G/H synthase in the rat				J Med Chem 32: 1176-83 (1989) BindingDB Entry DOI: 10.7270/Q2833R1T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50006820 (2-[3-(1H-Tetrazol-5-ylmethyl)-phenoxymethyl]-quino...) Show SMILES C(Oc1cccc(Cc2nnn[nH]2)c1)c1ccc2ccccc2n1 Show InChI InChI=1S/C18H15N5O/c1-2-7-17-14(5-1)8-9-15(19-17)12-24-16-6-3-4-13(10-16)11-18-20-22-23-21-18/h1-10H,11-12H2,(H,20,21,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Concentration that produces 50% inhibition of A-23,187-stimulated radiolabelled 5-HETE and TXB2 synthesis by PMN 5-lipoxygenase				J Med Chem 33: 240-5 (1990) BindingDB Entry DOI: 10.7270/Q24Q7T0P
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50006806 (C,C,C-Trifluoro-N-[3-(quinolin-2-ylmethoxy)-phenyl...) Show SMILES FC(F)(F)S(=O)(=O)Nc1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C17H13F3N2O3S/c18-17(19,20)26(23,24)22-13-5-3-6-15(10-13)25-11-14-9-8-12-4-1-2-7-16(12)21-14/h1-10,22H,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibitory concentration of the compound to inhibit 5-lipoxygenase in the rat				J Med Chem 32: 1176-83 (1989) BindingDB Entry DOI: 10.7270/Q2833R1T
					More data for this Ligand-Target Pair
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50282921 ((1R,4bR,10aS,12S,12aS)-12-Acetoxy-4b,7,7,10a,12a-p...) Show SMILES CC(=O)O[C@H]1CC2[C@@]3(C)CCCC(C)(C)C3CC[C@@]2(C)C2CC=C([C@H](C(O)=O)[C@@]12C)C(O)=O |c:24| Show InChI InChI=1S/C27H40O6/c1-15(28)33-20-14-19-25(4)12-7-11-24(2,3)17(25)10-13-26(19,5)18-9-8-16(22(29)30)21(23(31)32)27(18,20)6/h8,17-21H,7,9-14H2,1-6H3,(H,29,30)(H,31,32)/t17?,18?,19?,20-,21+,25-,26-,27+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibitory activity against human synovial fluid phospholipase A2 (HSF-PLA2) by monitoring hydrolysis of [3H]-arachidonic acid labeled E. co...				Bioorg Med Chem Lett 4: 1873-1878 (1994) Article DOI: 10.1016/S0960-894X(01)80388-7 BindingDB Entry DOI: 10.7270/Q2SB45PR
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (Homo sapiens (Human))	BDBM50012434 ((REV-5,901)1-[3-(Quinolin-2-ylmethoxy)-phenyl]-hex...) Show SMILES CCCCCC(O)c1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C22H25NO2/c1-2-3-4-12-22(24)18-9-7-10-20(15-18)25-16-19-14-13-17-8-5-6-11-21(17)23-19/h5-11,13-15,22,24H,2-4,12,16H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Laboratories Curated by ChEMBL					Assay Description Ability to inhibit Prostaglandin G/H synthase in guinea pig				J Med Chem 30: 2087-93 (1987) BindingDB Entry DOI: 10.7270/Q2FQ9VMQ
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50022209 (CHEMBL33109 | N-[3-(Quinolin-2-ylmethoxy)-phenyl]-...) Show SMILES COC(=O)C(=O)Nc1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C19H16N2O4/c1-24-19(23)18(22)21-14-6-4-7-16(11-14)25-12-15-10-9-13-5-2-3-8-17(13)20-15/h2-11H,12H2,1H3,(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat polymorphonuclear leukocyte (PMN) 5-Lipoxygenase in vitro				J Med Chem 29: 1429-35 (1986) BindingDB Entry DOI: 10.7270/Q2GX49K4
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50022202 (CHEMBL284706 | N-Hydroxy-N-[3-(naphthalen-2-yloxym...) Show SMILES COC(=O)CCC(=O)N(O)c1cccc(COc2ccc3ccccc3c2)c1 Show InChI InChI=1S/C22H21NO5/c1-27-22(25)12-11-21(24)23(26)19-8-4-5-16(13-19)15-28-20-10-9-17-6-2-3-7-18(17)14-20/h2-10,13-14,26H,11-12,15H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of rat polymorphonuclear leukocyte (PMN) Prostaglandin G/H synthase				J Med Chem 29: 1429-35 (1986) BindingDB Entry DOI: 10.7270/Q2GX49K4
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50006821 (4-Methyl-N-[3-(quinolin-2-ylmethoxy)-benzoyl]-benz...) Show SMILES Cc1ccc(cc1)S(=O)(=O)NC(=O)c1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C24H20N2O4S/c1-17-9-13-22(14-10-17)31(28,29)26-24(27)19-6-4-7-21(15-19)30-16-20-12-11-18-5-2-3-8-23(18)25-20/h2-15H,16H2,1H3,(H,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Concentration that produces 50% inhibition of A-23,187-stimulated radiolabelled 5-HETE and TXB2 synthesis by PMN 5-lipoxygenase.				J Med Chem 33: 240-5 (1990) BindingDB Entry DOI: 10.7270/Q24Q7T0P
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50022213 (CHEMBL285624 | N-[3-(Naphthalen-2-ylmethoxy)-pheny...) Show SMILES COC(=O)C(=O)Nc1cccc(OCc2ccc3ccccc3c2)c1 Show InChI InChI=1S/C20H17NO4/c1-24-20(23)19(22)21-17-7-4-8-18(12-17)25-13-14-9-10-15-5-2-3-6-16(15)11-14/h2-12H,13H2,1H3,(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat polymorphonuclear leukocyte (PMN) 5-Lipoxygenase in vitro				J Med Chem 29: 1429-35 (1986) BindingDB Entry DOI: 10.7270/Q2GX49K4
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50025770 (CHEMBL334848 | N-[3-(1-Methyl-1H-benzoimidazol-2-y...) Show SMILES COC(=O)CCC(=O)Nc1cccc(OCc2nc3ccccc3n2C)c1 Show InChI InChI=1S/C20H21N3O4/c1-23-17-9-4-3-8-16(17)22-18(23)13-27-15-7-5-6-14(12-15)21-19(24)10-11-20(25)26-2/h3-9,12H,10-11,13H2,1-2H3,(H,21,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	7.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit Lipoxygenase in vitro was determined				J Med Chem 30: 400-5 (1987) BindingDB Entry DOI: 10.7270/Q2K936JS
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50022203 (CHEMBL33734 | N-Hydroxy-N-[3-(naphthalen-2-ylmetho...) Show SMILES COC(=O)CCC(=O)N(O)c1cccc(OCc2ccc3ccccc3c2)c1 Show InChI InChI=1S/C22H21NO5/c1-27-22(25)12-11-21(24)23(26)19-7-4-8-20(14-19)28-15-16-9-10-17-5-2-3-6-18(17)13-16/h2-10,13-14,26H,11-12,15H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro inhibition of rat polymorphonuclear leukocyte (PMN) Prostaglandin G/H synthase				J Med Chem 29: 1429-35 (1986) BindingDB Entry DOI: 10.7270/Q2GX49K4
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50022207 (CHEMBL34672 | N-[2-Methyl-5-(quinolin-2-ylmethoxy)...) Show SMILES COC(=O)CCC(=O)Nc1cc(OCc2ccc3ccccc3n2)ccc1C Show InChI InChI=1S/C22H22N2O4/c1-15-7-10-18(13-20(15)24-21(25)11-12-22(26)27-2)28-14-17-9-8-16-5-3-4-6-19(16)23-17/h3-10,13H,11-12,14H2,1-2H3,(H,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat polymorphonuclear leukocyte (PMN) 5-Lipoxygenase in vitro				J Med Chem 29: 1429-35 (1986) BindingDB Entry DOI: 10.7270/Q2GX49K4
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50006806 (C,C,C-Trifluoro-N-[3-(quinolin-2-ylmethoxy)-phenyl...) Show SMILES FC(F)(F)S(=O)(=O)Nc1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C17H13F3N2O3S/c18-17(19,20)26(23,24)22-13-5-3-6-15(10-13)25-11-14-9-8-12-4-1-2-7-16(12)21-14/h1-10,22H,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Concentration for 50% inhibition of A-23187-stimulated radiolabeled 5-HETE and TXB2 synthesis by Prostaglandin G/H synthase				J Med Chem 33: 240-5 (1990) BindingDB Entry DOI: 10.7270/Q24Q7T0P
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50022197 (CHEMBL286178 | N-[3-(Naphthalen-2-ylmethoxy)-pheny...) Show SMILES COC(=O)CC(=O)Nc1cccc(OCc2ccc3ccccc3c2)c1 Show InChI InChI=1S/C21H19NO4/c1-25-21(24)13-20(23)22-18-7-4-8-19(12-18)26-14-15-9-10-16-5-2-3-6-17(16)11-15/h2-12H,13-14H2,1H3,(H,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	9.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat polymorphonuclear leukocyte (PMN) 5-Lipoxygenase in vitro				J Med Chem 29: 1429-35 (1986) BindingDB Entry DOI: 10.7270/Q2GX49K4
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50022200 (4-[3-(Quinolin-2-ylmethoxy)-phenylcarbamoyl]-butyr...) Show SMILES COC(=O)CCCC(=O)Nc1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C22H22N2O4/c1-27-22(26)11-5-10-21(25)24-17-7-4-8-19(14-17)28-15-18-13-12-16-6-2-3-9-20(16)23-18/h2-4,6-9,12-14H,5,10-11,15H2,1H3,(H,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.04E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat polymorphonuclear leukocyte (PMN) 5-Lipoxygenase in vitro				J Med Chem 29: 1429-35 (1986) BindingDB Entry DOI: 10.7270/Q2GX49K4
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50016627 (C,C,C-Trifluoro-N-[7-(quinolin-2-ylmethoxy)-naphth...) Show SMILES FC(F)(F)S(=O)(=O)Nc1ccc2ccc(OCc3ccc4ccccc4n3)cc2c1 Show InChI InChI=1S/C21H15F3N2O3S/c22-21(23,24)30(27,28)26-17-8-5-14-7-10-19(12-16(14)11-17)29-13-18-9-6-15-3-1-2-4-20(15)25-18/h1-12,26H,13H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.19E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibitory concentration to inhibit Prostaglandin G/H synthase in the rat				J Med Chem 32: 1176-83 (1989) BindingDB Entry DOI: 10.7270/Q2833R1T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50022204 (CHEMBL34225 | N-[3-(Quinolin-2-ylmethoxy)-phenyl]-...) Show SMILES CCOC(=O)CCC(=O)Nc1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C22H22N2O4/c1-2-27-22(26)13-12-21(25)24-17-7-5-8-19(14-17)28-15-18-11-10-16-6-3-4-9-20(16)23-18/h3-11,14H,2,12-13,15H2,1H3,(H,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat polymorphonuclear leukocyte (PMN) 5-Lipoxygenase in vitro				J Med Chem 29: 1429-35 (1986) BindingDB Entry DOI: 10.7270/Q2GX49K4
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50022194 (4-[3-(Naphthalen-2-ylmethoxy)-phenylcarbamoyl]-but...) Show SMILES COC(=O)CCCC(=O)Nc1cccc(OCc2ccc3ccccc3c2)c1 Show InChI InChI=1S/C23H23NO4/c1-27-23(26)11-5-10-22(25)24-20-8-4-9-21(15-20)28-16-17-12-13-18-6-2-3-7-19(18)14-17/h2-4,6-9,12-15H,5,10-11,16H2,1H3,(H,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat polymorphonuclear leukocyte (PMN) 5-Lipoxygenase in vitro				J Med Chem 29: 1429-35 (1986) BindingDB Entry DOI: 10.7270/Q2GX49K4
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50006821 (4-Methyl-N-[3-(quinolin-2-ylmethoxy)-benzoyl]-benz...) Show SMILES Cc1ccc(cc1)S(=O)(=O)NC(=O)c1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C24H20N2O4S/c1-17-9-13-22(14-10-17)31(28,29)26-24(27)19-6-4-7-21(15-19)30-16-20-12-11-18-5-2-3-8-23(18)25-20/h2-15H,16H2,1H3,(H,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.34E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Concentration that produces 50% inhibition of A-23187-stimulated radiolabeled 5-HETE and TXB2 synthesis by Prostaglandin G/H synthase				J Med Chem 33: 240-5 (1990) BindingDB Entry DOI: 10.7270/Q24Q7T0P
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50022212 (CHEMBL33167 | N-Methyl-N-[3-(quinolin-2-ylmethoxy)...) Show SMILES COC(=O)CCC(=O)N(C)c1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C22H22N2O4/c1-24(21(25)12-13-22(26)27-2)18-7-5-8-19(14-18)28-15-17-11-10-16-6-3-4-9-20(16)23-17/h3-11,14H,12-13,15H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat polymorphonuclear leukocyte (PMN) 5-Lipoxygenase in vitro				J Med Chem 29: 1429-35 (1986) BindingDB Entry DOI: 10.7270/Q2GX49K4
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50025772 (1-[3-(Benzothiazol-2-ylmethoxy)-phenyl]-5-oxo-pyrr...) Show SMILES COC(=O)C1CN(C(=O)C1)c1cccc(OCc2nc3ccccc3s2)c1 Show InChI InChI=1S/C20H18N2O4S/c1-25-20(24)13-9-19(23)22(11-13)14-5-4-6-15(10-14)26-12-18-21-16-7-2-3-8-17(16)27-18/h2-8,10,13H,9,11-12H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit Lipoxygenase in vitro was determined				J Med Chem 30: 400-5 (1987) BindingDB Entry DOI: 10.7270/Q2K936JS
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50006813 (CHEMBL79453 | N-Methoxy-2-[3-(quinolin-2-ylmethoxy...) Show SMILES CONC(=O)Cc1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C19H18N2O3/c1-23-21-19(22)12-14-5-4-7-17(11-14)24-13-16-10-9-15-6-2-3-8-18(15)20-16/h2-11H,12-13H2,1H3,(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.42E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Concentration for 50% inhibition of A-23,187-stimulated radiolabelled 5-HETE and TXB2 synthesis by PMN 5-lipoxygenase				J Med Chem 33: 240-5 (1990) BindingDB Entry DOI: 10.7270/Q24Q7T0P
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50022198 (CHEMBL33465 | N-[2-Methyl-3-(quinolin-2-ylmethoxy)...) Show SMILES COC(=O)CCC(=O)Nc1cccc(OCc2ccc3ccccc3n2)c1C Show InChI InChI=1S/C22H22N2O4/c1-15-18(24-21(25)12-13-22(26)27-2)8-5-9-20(15)28-14-17-11-10-16-6-3-4-7-19(16)23-17/h3-11H,12-14H2,1-2H3,(H,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.55E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat polymorphonuclear leukocyte (PMN) 5-Lipoxygenase in vitro				J Med Chem 29: 1429-35 (1986) BindingDB Entry DOI: 10.7270/Q2GX49K4
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50025766 (CHEMBL130819 | N-[3-(Benzothiazol-2-ylmethoxy)-phe...) Show SMILES COC(=O)CCC(=O)Nc1cccc(OCc2nc3ccccc3s2)c1 Show InChI InChI=1S/C19H18N2O4S/c1-24-19(23)10-9-17(22)20-13-5-4-6-14(11-13)25-12-18-21-15-7-2-3-8-16(15)26-18/h2-8,11H,9-10,12H2,1H3,(H,20,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.57E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the rat Lipoxygenase in vitro was determined				J Med Chem 30: 400-5 (1987) BindingDB Entry DOI: 10.7270/Q2K936JS
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50022201 (CHEMBL34676 | Sodium; 3-{hydroxy-[3-(naphthalen-2-...) Show SMILES ON(C(=O)CCC([O-])=O)c1cccc(OCc2ccc3ccccc3c2)c1 Show InChI InChI=1S/C21H19NO5/c23-20(10-11-21(24)25)22(26)18-6-3-7-19(13-18)27-14-15-8-9-16-4-1-2-5-17(16)12-15/h1-9,12-13,26H,10-11,14H2,(H,24,25)/p-1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.57E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat polymorphonuclear leukocyte (PMN) 5-Lipoxygenase in vitro				J Med Chem 29: 1429-35 (1986) BindingDB Entry DOI: 10.7270/Q2GX49K4
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50025769 (CHEMBL341255 | N-[3-(Benzothiazol-2-ylmethoxy)-phe...) Show SMILES COC(=O)CC(=O)Nc1cccc(OCc2nc3ccccc3s2)c1 Show InChI InChI=1S/C18H16N2O4S/c1-23-18(22)10-16(21)19-12-5-4-6-13(9-12)24-11-17-20-14-7-2-3-8-15(14)25-17/h2-9H,10-11H2,1H3,(H,19,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit Lipoxygenase in vitro was determined				J Med Chem 30: 400-5 (1987) BindingDB Entry DOI: 10.7270/Q2K936JS
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50025767 (CHEMBL131423 | N-[3-(Benzofuran-2-ylmethoxy)-pheny...) Show SMILES COC(=O)CCC(=O)Nc1cccc(OCc2cc3ccccc3o2)c1 Show InChI InChI=1S/C20H19NO5/c1-24-20(23)10-9-19(22)21-15-6-4-7-16(12-15)25-13-17-11-14-5-2-3-8-18(14)26-17/h2-8,11-12H,9-10,13H2,1H3,(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.79E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit Lipoxygenase in vitro was determined				J Med Chem 30: 400-5 (1987) BindingDB Entry DOI: 10.7270/Q2K936JS
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50006816 ((LY-171883)1-{2-Hydroxy-3-propyl-4-[4-(1H-tetrazol...) Show SMILES CCCc1c(OCCCCc2nnn[nH]2)ccc(C(C)=O)c1O Show InChI InChI=1S/C16H22N4O3/c1-3-6-13-14(9-8-12(11(2)21)16(13)22)23-10-5-4-7-15-17-19-20-18-15/h8-9,22H,3-7,10H2,1-2H3,(H,17,18,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.89E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Concentration for 50% inhibition of A-23,187-stimulated radiolabelled 5-HETE and TXB2 synthesis by PMN 5-lipoxygenase				J Med Chem 33: 240-5 (1990) BindingDB Entry DOI: 10.7270/Q24Q7T0P
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50006816 ((LY-171883)1-{2-Hydroxy-3-propyl-4-[4-(1H-tetrazol...) Show SMILES CCCc1c(OCCCCc2nnn[nH]2)ccc(C(C)=O)c1O Show InChI InChI=1S/C16H22N4O3/c1-3-6-13-14(9-8-12(11(2)21)16(13)22)23-10-5-4-7-15-17-19-20-18-15/h8-9,22H,3-7,10H2,1-2H3,(H,17,18,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.89E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit Lipoxygenase in vitro was determined				J Med Chem 30: 400-5 (1987) BindingDB Entry DOI: 10.7270/Q2K936JS
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50006816 ((LY-171883)1-{2-Hydroxy-3-propyl-4-[4-(1H-tetrazol...) Show SMILES CCCc1c(OCCCCc2nnn[nH]2)ccc(C(C)=O)c1O Show InChI InChI=1S/C16H22N4O3/c1-3-6-13-14(9-8-12(11(2)21)16(13)22)23-10-5-4-7-15-17-19-20-18-15/h8-9,22H,3-7,10H2,1-2H3,(H,17,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.89E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Laboratories Curated by ChEMBL					Assay Description Ability to inhibit 5-lipoxygenase in guinea pig				J Med Chem 30: 2087-93 (1987) BindingDB Entry DOI: 10.7270/Q2FQ9VMQ
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50022199 (CHEMBL33437 | N-[3-(Quinolin-2-ylmethoxy)-phenyl]-...) Show SMILES CCOC(=O)CC(=O)Nc1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C21H20N2O4/c1-2-26-21(25)13-20(24)23-16-7-5-8-18(12-16)27-14-17-11-10-15-6-3-4-9-19(15)22-17/h3-12H,2,13-14H2,1H3,(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat polymorphonuclear leukocyte (PMN) 5-Lipoxygenase in vitro				J Med Chem 29: 1429-35 (1986) BindingDB Entry DOI: 10.7270/Q2GX49K4
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50025764 (5-Oxo-1-[3-(quinolin-2-ylmethoxy)-phenyl]-pyrrolid...) Show SMILES COC(=O)C1CN(C(=O)C1)c1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C22H20N2O4/c1-27-22(26)16-11-21(25)24(13-16)18-6-4-7-19(12-18)28-14-17-10-9-15-5-2-3-8-20(15)23-17/h2-10,12,16H,11,13-14H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.91E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit Lipoxygenase in vitro was determined				J Med Chem 30: 400-5 (1987) BindingDB Entry DOI: 10.7270/Q2K936JS
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50405505 (CHEMBL2115108) Show SMILES CN1C[C@H](OC1=O)c1cccc(OCc2ccc3ccccc3n2)c1 |r| Show InChI InChI=1S/C20H18N2O3/c1-22-12-19(25-20(22)23)15-6-4-7-17(11-15)24-13-16-10-9-14-5-2-3-8-18(14)21-16/h2-11,19H,12-13H2,1H3/t19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.96E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Laboratories Curated by ChEMBL					Assay Description Ability to inhibit 5-lipoxygenase in guinea pig				J Med Chem 30: 2087-93 (1987) BindingDB Entry DOI: 10.7270/Q2FQ9VMQ
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50025762 (CHEMBL130717 | N-[3-(Benzothiazol-2-ylmethoxy)-phe...) Show SMILES COC(=O)CCC(=O)N(C)c1cccc(OCc2nc3ccccc3s2)c1 Show InChI InChI=1S/C20H20N2O4S/c1-22(19(23)10-11-20(24)25-2)14-6-5-7-15(12-14)26-13-18-21-16-8-3-4-9-17(16)27-18/h3-9,12H,10-11,13H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit Lipoxygenase in vitro was determined				J Med Chem 30: 400-5 (1987) BindingDB Entry DOI: 10.7270/Q2K936JS
					More data for this Ligand-Target Pair

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