Compile Data Set for Download or QSAR

Found 77 hits with Last Name = 'lamothe' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50454655 (CHEMBL2111779) Show SMILES COc1ccc(cc1\C=C/CN(C)C)C(=O)Nc1ccc(cc1)-c1ccncc1 Show InChI InChI=1S/C24H25N3O2/c1-27(2)16-4-5-20-17-21(8-11-23(20)29-3)24(28)26-22-9-6-18(7-10-22)19-12-14-25-15-13-19/h4-15,17H,16H2,1-3H3,(H,26,28)/b5-4-	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound for 5-hydroxytryptamine 1B receptor in C6-glial transfected cell type using [3H]-GR-125,743 as radioligand				J Med Chem 40: 3542-50 (1997) Article DOI: 10.1021/jm9702948 BindingDB Entry DOI: 10.7270/Q21R6PNK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50060519 (3-(3-Dimethylamino-propyl)-4-hydroxy-N-(4-pyridin-...) Show SMILES CN(C)CCCc1cc(ccc1O)C(=O)Nc1ccc(cc1)-c1ccncc1 Show InChI InChI=1S/C23H25N3O2/c1-26(2)15-3-4-19-16-20(7-10-22(19)27)23(28)25-21-8-5-17(6-9-21)18-11-13-24-14-12-18/h5-14,16,27H,3-4,15H2,1-2H3,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	12.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound for 5-hydroxytryptamine 1B receptor in C6-glial transfected cell type using [3H]-5-CT as radioligand				J Med Chem 40: 3542-50 (1997) Article DOI: 10.1021/jm9702948 BindingDB Entry DOI: 10.7270/Q21R6PNK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50060516 (3-((E)-3-Dimethylamino-propenyl)-4-methoxy-N-(4-py...) Show SMILES COc1ccc(cc1\C=C\CN(C)C)C(=O)Nc1ccc(cc1)-c1ccncc1 Show InChI InChI=1S/C24H25N3O2/c1-27(2)16-4-5-20-17-21(8-11-23(20)29-3)24(28)26-22-9-6-18(7-10-22)19-12-14-25-15-13-19/h4-15,17H,16H2,1-3H3,(H,26,28)/b5-4+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound for 5-hydroxytryptamine 1B receptor in C6-glial transfected cell type using [3H]-5-CT as radioligand				J Med Chem 40: 3542-50 (1997) Article DOI: 10.1021/jm9702948 BindingDB Entry DOI: 10.7270/Q21R6PNK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50060519 (3-(3-Dimethylamino-propyl)-4-hydroxy-N-(4-pyridin-...) Show SMILES CN(C)CCCc1cc(ccc1O)C(=O)Nc1ccc(cc1)-c1ccncc1 Show InChI InChI=1S/C23H25N3O2/c1-26(2)15-3-4-19-16-20(7-10-22(19)27)23(28)25-21-8-5-17(6-9-21)18-11-13-24-14-12-18/h5-14,16,27H,3-4,15H2,1-2H3,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound for 5-hydroxytryptamine 1B receptor in C6-glial transfected cell type using [3H]-GR-125,743 as radioligand				J Med Chem 40: 3542-50 (1997) Article DOI: 10.1021/jm9702948 BindingDB Entry DOI: 10.7270/Q21R6PNK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50060518 (3-(3-Dimethylamino-propyl)-4-methoxy-N-(4-pyridin-...) Show SMILES COc1ccc(cc1CCCN(C)C)C(=O)Nc1ccc(cc1)-c1ccncc1 Show InChI InChI=1S/C24H27N3O2/c1-27(2)16-4-5-20-17-21(8-11-23(20)29-3)24(28)26-22-9-6-18(7-10-22)19-12-14-25-15-13-19/h6-15,17H,4-5,16H2,1-3H3,(H,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound for 5-hydroxytryptamine 1B receptor in C6-glial transfected cell type using [3H]-GR-125,743 as radioligand				J Med Chem 40: 3542-50 (1997) Article DOI: 10.1021/jm9702948 BindingDB Entry DOI: 10.7270/Q21R6PNK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50060517 (3-(3-Dimethylamino-prop-1-ynyl)-4-methoxy-N-(4-pyr...) Show SMILES COc1ccc(cc1C#CCN(C)C)C(=O)Nc1ccc(cc1)-c1ccncc1 Show InChI InChI=1S/C24H23N3O2/c1-27(2)16-4-5-20-17-21(8-11-23(20)29-3)24(28)26-22-9-6-18(7-10-22)19-12-14-25-15-13-19/h6-15,17H,16H2,1-3H3,(H,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound for 5-hydroxytryptamine 1B receptor in C6-glial transfected cell type using [3H]-5-CT as radioligand				J Med Chem 40: 3542-50 (1997) Article DOI: 10.1021/jm9702948 BindingDB Entry DOI: 10.7270/Q21R6PNK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50060516 (3-((E)-3-Dimethylamino-propenyl)-4-methoxy-N-(4-py...) Show SMILES COc1ccc(cc1\C=C\CN(C)C)C(=O)Nc1ccc(cc1)-c1ccncc1 Show InChI InChI=1S/C24H25N3O2/c1-27(2)16-4-5-20-17-21(8-11-23(20)29-3)24(28)26-22-9-6-18(7-10-22)19-12-14-25-15-13-19/h4-15,17H,16H2,1-3H3,(H,26,28)/b5-4+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound for 5-hydroxytryptamine 1B receptor in C6-glial transfected cell type using [3H]-GR-125,743 as radioligand				J Med Chem 40: 3542-50 (1997) Article DOI: 10.1021/jm9702948 BindingDB Entry DOI: 10.7270/Q21R6PNK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50454655 (CHEMBL2111779) Show SMILES COc1ccc(cc1\C=C/CN(C)C)C(=O)Nc1ccc(cc1)-c1ccncc1 Show InChI InChI=1S/C24H25N3O2/c1-27(2)16-4-5-20-17-21(8-11-23(20)29-3)24(28)26-22-9-6-18(7-10-22)19-12-14-25-15-13-19/h4-15,17H,16H2,1-3H3,(H,26,28)/b5-4-	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound for 5-hydroxytryptamine 1B receptor in C6-glial transfected cell type using [3H]-5-CT as radioligand				J Med Chem 40: 3542-50 (1997) Article DOI: 10.1021/jm9702948 BindingDB Entry DOI: 10.7270/Q21R6PNK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50060517 (3-(3-Dimethylamino-prop-1-ynyl)-4-methoxy-N-(4-pyr...) Show SMILES COc1ccc(cc1C#CCN(C)C)C(=O)Nc1ccc(cc1)-c1ccncc1 Show InChI InChI=1S/C24H23N3O2/c1-27(2)16-4-5-20-17-21(8-11-23(20)29-3)24(28)26-22-9-6-18(7-10-22)19-12-14-25-15-13-19/h6-15,17H,16H2,1-3H3,(H,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	22.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound for 5-hydroxytryptamine 1B receptor in C6-glial transfected cell type using [3H]-GR-125,743 as radioligand				J Med Chem 40: 3542-50 (1997) Article DOI: 10.1021/jm9702948 BindingDB Entry DOI: 10.7270/Q21R6PNK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50060518 (3-(3-Dimethylamino-propyl)-4-methoxy-N-(4-pyridin-...) Show SMILES COc1ccc(cc1CCCN(C)C)C(=O)Nc1ccc(cc1)-c1ccncc1 Show InChI InChI=1S/C24H27N3O2/c1-27(2)16-4-5-20-17-21(8-11-23(20)29-3)24(28)26-22-9-6-18(7-10-22)19-12-14-25-15-13-19/h6-15,17H,4-5,16H2,1-3H3,(H,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	70.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound for 5-hydroxytryptamine 1B receptor in C6-glial transfected cell type using [3H]-5-CT as radioligand				J Med Chem 40: 3542-50 (1997) Article DOI: 10.1021/jm9702948 BindingDB Entry DOI: 10.7270/Q21R6PNK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50454655 (CHEMBL2111779) Show SMILES COc1ccc(cc1\C=C/CN(C)C)C(=O)Nc1ccc(cc1)-c1ccncc1 Show InChI InChI=1S/C24H25N3O2/c1-27(2)16-4-5-20-17-21(8-11-23(20)29-3)24(28)26-22-9-6-18(7-10-22)19-12-14-25-15-13-19/h4-15,17H,16H2,1-3H3,(H,26,28)/b5-4-	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	169	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound for 5-hydroxytryptamine 1D receptor in Cos-7 transfected cell type using [3H]-5-CT as radioligand				J Med Chem 40: 3542-50 (1997) Article DOI: 10.1021/jm9702948 BindingDB Entry DOI: 10.7270/Q21R6PNK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50060518 (3-(3-Dimethylamino-propyl)-4-methoxy-N-(4-pyridin-...) Show SMILES COc1ccc(cc1CCCN(C)C)C(=O)Nc1ccc(cc1)-c1ccncc1 Show InChI InChI=1S/C24H27N3O2/c1-27(2)16-4-5-20-17-21(8-11-23(20)29-3)24(28)26-22-9-6-18(7-10-22)19-12-14-25-15-13-19/h6-15,17H,4-5,16H2,1-3H3,(H,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	540	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound for 5-hydroxytryptamine 1D receptor in Cos-7 transfected cell type using [3H]-5-CT as radioligand				J Med Chem 40: 3542-50 (1997) Article DOI: 10.1021/jm9702948 BindingDB Entry DOI: 10.7270/Q21R6PNK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50060516 (3-((E)-3-Dimethylamino-propenyl)-4-methoxy-N-(4-py...) Show SMILES COc1ccc(cc1\C=C\CN(C)C)C(=O)Nc1ccc(cc1)-c1ccncc1 Show InChI InChI=1S/C24H25N3O2/c1-27(2)16-4-5-20-17-21(8-11-23(20)29-3)24(28)26-22-9-6-18(7-10-22)19-12-14-25-15-13-19/h4-15,17H,16H2,1-3H3,(H,26,28)/b5-4+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	560	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound for 5-hydroxytryptamine 1D receptor in Cos-7 transfected cell type using [3H]-5-CT as radioligand				J Med Chem 40: 3542-50 (1997) Article DOI: 10.1021/jm9702948 BindingDB Entry DOI: 10.7270/Q21R6PNK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50454655 (CHEMBL2111779) Show SMILES COc1ccc(cc1\C=C/CN(C)C)C(=O)Nc1ccc(cc1)-c1ccncc1 Show InChI InChI=1S/C24H25N3O2/c1-27(2)16-4-5-20-17-21(8-11-23(20)29-3)24(28)26-22-9-6-18(7-10-22)19-12-14-25-15-13-19/h4-15,17H,16H2,1-3H3,(H,26,28)/b5-4-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	633	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound for 5-hydroxytryptamine 1A receptor in HeLa transfected cell type using [3H]-8-OH-DPAT as radioligand				J Med Chem 40: 3542-50 (1997) Article DOI: 10.1021/jm9702948 BindingDB Entry DOI: 10.7270/Q21R6PNK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50060519 (3-(3-Dimethylamino-propyl)-4-hydroxy-N-(4-pyridin-...) Show SMILES CN(C)CCCc1cc(ccc1O)C(=O)Nc1ccc(cc1)-c1ccncc1 Show InChI InChI=1S/C23H25N3O2/c1-26(2)15-3-4-19-16-20(7-10-22(19)27)23(28)25-21-8-5-17(6-9-21)18-11-13-24-14-12-18/h5-14,16,27H,3-4,15H2,1-2H3,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound for 5-hydroxytryptamine 1D receptor in Cos-7 transfected cell type using [3H]-5-CT as radioligand				J Med Chem 40: 3542-50 (1997) Article DOI: 10.1021/jm9702948 BindingDB Entry DOI: 10.7270/Q21R6PNK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50060519 (3-(3-Dimethylamino-propyl)-4-hydroxy-N-(4-pyridin-...) Show SMILES CN(C)CCCc1cc(ccc1O)C(=O)Nc1ccc(cc1)-c1ccncc1 Show InChI InChI=1S/C23H25N3O2/c1-26(2)15-3-4-19-16-20(7-10-22(19)27)23(28)25-21-8-5-17(6-9-21)18-11-13-24-14-12-18/h5-14,16,27H,3-4,15H2,1-2H3,(H,25,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	842	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound for 5-hydroxytryptamine 1A receptor in HeLa transfected cell type using [3H]-8-OH-DPAT as radioligand				J Med Chem 40: 3542-50 (1997) Article DOI: 10.1021/jm9702948 BindingDB Entry DOI: 10.7270/Q21R6PNK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50060517 (3-(3-Dimethylamino-prop-1-ynyl)-4-methoxy-N-(4-pyr...) Show SMILES COc1ccc(cc1C#CCN(C)C)C(=O)Nc1ccc(cc1)-c1ccncc1 Show InChI InChI=1S/C24H23N3O2/c1-27(2)16-4-5-20-17-21(8-11-23(20)29-3)24(28)26-22-9-6-18(7-10-22)19-12-14-25-15-13-19/h6-15,17H,16H2,1-3H3,(H,26,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound for 5-hydroxytryptamine 1A receptor in HeLa transfected cell type using [3H]-8-OH-DPAT as radioligand				J Med Chem 40: 3542-50 (1997) Article DOI: 10.1021/jm9702948 BindingDB Entry DOI: 10.7270/Q21R6PNK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50060516 (3-((E)-3-Dimethylamino-propenyl)-4-methoxy-N-(4-py...) Show SMILES COc1ccc(cc1\C=C\CN(C)C)C(=O)Nc1ccc(cc1)-c1ccncc1 Show InChI InChI=1S/C24H25N3O2/c1-27(2)16-4-5-20-17-21(8-11-23(20)29-3)24(28)26-22-9-6-18(7-10-22)19-12-14-25-15-13-19/h4-15,17H,16H2,1-3H3,(H,26,28)/b5-4+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound for 5-hydroxytryptamine 1A receptor in HeLa transfected cell type using [3H]-8-OH-DPAT as radioligand				J Med Chem 40: 3542-50 (1997) Article DOI: 10.1021/jm9702948 BindingDB Entry DOI: 10.7270/Q21R6PNK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50060518 (3-(3-Dimethylamino-propyl)-4-methoxy-N-(4-pyridin-...) Show SMILES COc1ccc(cc1CCCN(C)C)C(=O)Nc1ccc(cc1)-c1ccncc1 Show InChI InChI=1S/C24H27N3O2/c1-27(2)16-4-5-20-17-21(8-11-23(20)29-3)24(28)26-22-9-6-18(7-10-22)19-12-14-25-15-13-19/h6-15,17H,4-5,16H2,1-3H3,(H,26,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound for 5-hydroxytryptamine 1A receptor in HeLa transfected cell type using [3H]-8-OH-DPAT as radioligand				J Med Chem 40: 3542-50 (1997) Article DOI: 10.1021/jm9702948 BindingDB Entry DOI: 10.7270/Q21R6PNK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50060517 (3-(3-Dimethylamino-prop-1-ynyl)-4-methoxy-N-(4-pyr...) Show SMILES COc1ccc(cc1C#CCN(C)C)C(=O)Nc1ccc(cc1)-c1ccncc1 Show InChI InChI=1S/C24H23N3O2/c1-27(2)16-4-5-20-17-21(8-11-23(20)29-3)24(28)26-22-9-6-18(7-10-22)19-12-14-25-15-13-19/h6-15,17H,16H2,1-3H3,(H,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre FABRE Curated by ChEMBL					Assay Description Binding affinity of the compound for 5-hydroxytryptamine 1D receptor in Cos-7 transfected cell type using [3H]-5-CT as radioligand				J Med Chem 40: 3542-50 (1997) Article DOI: 10.1021/jm9702948 BindingDB Entry DOI: 10.7270/Q21R6PNK
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50126556 (CHEMBL34828 | N-{4-[4-(5-Chloro-thiophene-2-carbon...) Show SMILES COc1ccc(cc1)C(=O)N(Cc1cncn1Cc1ccc(cc1)C#N)c1ccc(cc1)N1CCN(CC1)C(=O)c1ccc(Cl)s1 Show InChI InChI=1S/C35H31ClN6O3S/c1-45-31-12-6-27(7-13-31)34(43)42(23-30-21-38-24-41(30)22-26-4-2-25(20-37)3-5-26)29-10-8-28(9-11-29)39-16-18-40(19-17-39)35(44)32-14-15-33(36)46-32/h2-15,21,24H,16-19,22-23H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre Fabre Curated by ChEMBL					Assay Description Inhibit of purified bovine Farnesyl protein transferase.				Bioorg Med Chem Lett 13: 1455-8 (2003) BindingDB Entry DOI: 10.7270/Q2NV9JSG
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50126549 (CHEMBL34143 | N-{4-[4-(5-Chloro-thiophene-2-carbon...) Show SMILES Fc1ccccc1C(=O)N(Cc1cncn1Cc1ccc(cc1)C#N)c1ccc(cc1)N1CCN(CC1)C(=O)c1ccc(Cl)s1 Show InChI InChI=1S/C34H28ClFN6O2S/c35-32-14-13-31(45-32)34(44)40-17-15-39(16-18-40)26-9-11-27(12-10-26)42(33(43)29-3-1-2-4-30(29)36)22-28-20-38-23-41(28)21-25-7-5-24(19-37)6-8-25/h1-14,20,23H,15-18,21-22H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre Fabre Curated by ChEMBL					Assay Description Inhibit of purified bovine Farnesyl protein transferase.				Bioorg Med Chem Lett 13: 1455-8 (2003) BindingDB Entry DOI: 10.7270/Q2NV9JSG
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50126554 (CHEMBL23405 | N-{4-[4-(5-Chloro-thiophene-2-carbon...) Show SMILES Clc1ccc(s1)C(=O)N1CCN(CC1)c1ccc(cc1)N(Cc1cncn1Cc1ccc(cc1)C#N)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C33H29ClN6O3S2/c34-32-15-14-31(44-32)33(41)38-18-16-37(17-19-38)27-10-12-28(13-11-27)40(45(42,43)30-4-2-1-3-5-30)23-29-21-36-24-39(29)22-26-8-6-25(20-35)7-9-26/h1-15,21,24H,16-19,22-23H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre Fabre Curated by ChEMBL					Assay Description Inhibit of purified bovine Farnesyl protein transferase.				Bioorg Med Chem Lett 13: 1455-8 (2003) BindingDB Entry DOI: 10.7270/Q2NV9JSG
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50126539 (CHEMBL286779 | N-{4-[4-(5-Chloro-thiophene-2-carbo...) Show SMILES Clc1ccc(s1)C(=O)N1CCN(CC1)c1ccc(cc1)N(Cc1cncn1Cc1ccc(cc1)C#N)C(=O)c1ccccc1 Show InChI InChI=1S/C34H29ClN6O2S/c35-32-15-14-31(44-32)34(43)39-18-16-38(17-19-39)28-10-12-29(13-11-28)41(33(42)27-4-2-1-3-5-27)23-30-21-37-24-40(30)22-26-8-6-25(20-36)7-9-26/h1-15,21,24H,16-19,22-23H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre Fabre Curated by ChEMBL					Assay Description Inhibit of purified bovine Farnesyl protein transferase.				Bioorg Med Chem Lett 13: 1455-8 (2003) BindingDB Entry DOI: 10.7270/Q2NV9JSG
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM24226 (1-[(4-fluorophenyl)methyl]-N-{1-[2-(4-methoxypheny...) Show SMILES COc1ccc(CCN2CCC(CC2)Nc2nc3ccccc3n2Cc2ccc(F)cc2)cc1 Show InChI InChI=1S/C28H31FN4O/c1-34-25-12-8-21(9-13-25)14-17-32-18-15-24(16-19-32)30-28-31-26-4-2-3-5-27(26)33(28)20-22-6-10-23(29)11-7-22/h2-13,24H,14-20H2,1H3,(H,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre Fabre Curated by ChEMBL					Assay Description Inhibit of purified bovine Farnesyl protein transferase.				Bioorg Med Chem Lett 13: 1455-8 (2003) BindingDB Entry DOI: 10.7270/Q2NV9JSG
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50126542 (CHEMBL35706 | N-{4-[4-(5-Chloro-thiophene-2-carbon...) Show SMILES Fc1cccc(c1)C(=O)N(Cc1cncn1Cc1ccc(cc1)C#N)c1ccc(cc1)N1CCN(CC1)C(=O)c1ccc(Cl)s1 Show InChI InChI=1S/C34H28ClFN6O2S/c35-32-13-12-31(45-32)34(44)40-16-14-39(15-17-40)28-8-10-29(11-9-28)42(33(43)26-2-1-3-27(36)18-26)22-30-20-38-23-41(30)21-25-6-4-24(19-37)5-7-25/h1-13,18,20,23H,14-17,21-22H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre Fabre Curated by ChEMBL					Assay Description Inhibit of purified bovine Farnesyl protein transferase.				Bioorg Med Chem Lett 13: 1455-8 (2003) BindingDB Entry DOI: 10.7270/Q2NV9JSG
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50126551 (3-Chloro-N-{4-[4-(5-chloro-thiophene-2-carbonyl)-p...) Show SMILES Clc1ccc(s1)C(=O)N1CCN(CC1)c1ccc(cc1)N(Cc1cncn1Cc1ccc(cc1)C#N)C(=O)c1cccc(Cl)c1 Show InChI InChI=1S/C34H28Cl2N6O2S/c35-27-3-1-2-26(18-27)33(43)42(22-30-20-38-23-41(30)21-25-6-4-24(19-37)5-7-25)29-10-8-28(9-11-29)39-14-16-40(17-15-39)34(44)31-12-13-32(36)45-31/h1-13,18,20,23H,14-17,21-22H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre Fabre Curated by ChEMBL					Assay Description Inhibit of purified bovine Farnesyl protein transferase.				Bioorg Med Chem Lett 13: 1455-8 (2003) BindingDB Entry DOI: 10.7270/Q2NV9JSG
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50126545 (CHEMBL284835 | N-{4-[4-(5-Chloro-thiophene-2-carbo...) Show SMILES COc1cccc(c1)C(=O)N(Cc1cncn1Cc1ccc(cc1)C#N)c1ccc(cc1)N1CCN(CC1)C(=O)c1ccc(Cl)s1 Show InChI InChI=1S/C35H31ClN6O3S/c1-45-31-4-2-3-27(19-31)34(43)42(23-30-21-38-24-41(30)22-26-7-5-25(20-37)6-8-26)29-11-9-28(10-12-29)39-15-17-40(18-16-39)35(44)32-13-14-33(36)46-32/h2-14,19,21,24H,15-18,22-23H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre Fabre Curated by ChEMBL					Assay Description Inhibit of purified bovine Farnesyl protein transferase.				Bioorg Med Chem Lett 13: 1455-8 (2003) BindingDB Entry DOI: 10.7270/Q2NV9JSG
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50126541 (CHEMBL32217 | N-{4-[4-(5-Chloro-thiophene-2-carbon...) Show SMILES COc1ccccc1C(=O)N(Cc1cncn1Cc1ccc(cc1)C#N)c1ccc(cc1)N1CCN(CC1)C(=O)c1ccc(Cl)s1 Show InChI InChI=1S/C35H31ClN6O3S/c1-45-31-5-3-2-4-30(31)34(43)42(23-29-21-38-24-41(29)22-26-8-6-25(20-37)7-9-26)28-12-10-27(11-13-28)39-16-18-40(19-17-39)35(44)32-14-15-33(36)46-32/h2-15,21,24H,16-19,22-23H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre Fabre Curated by ChEMBL					Assay Description Inhibit of purified bovine Farnesyl protein transferase.				Bioorg Med Chem Lett 13: 1455-8 (2003) BindingDB Entry DOI: 10.7270/Q2NV9JSG
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50126561 ((4E,8E)-2-{[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmet...) Show SMILES [#6]\[#6](-[#6])=[#6]/[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6](-[#7]-[#6]-c1cncn1-[#6]-c1ccc(cc1)C#N)-[#6](=O)-[#7]-[#6]-c1ccccc1 Show InChI InChI=1S/C36H45N5O/c1-28(2)10-8-11-29(3)12-9-13-30(4)16-21-35(36(42)40-23-32-14-6-5-7-15-32)39-25-34-24-38-27-41(34)26-33-19-17-31(22-37)18-20-33/h5-7,10,12,14-20,24,27,35,39H,8-9,11,13,21,23,25-26H2,1-4H3,(H,40,42)/b29-12+,30-16+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre Fabre Curated by ChEMBL					Assay Description In vitro inhibition of bovine Farnesyl transferase				Bioorg Med Chem Lett 13: 1459-62 (2003) BindingDB Entry DOI: 10.7270/Q2TX3DSS
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50126537 (4-{4-[Benzenesulfonyl-(3H-imidazol-4-ylmethyl)-ami...) Show SMILES CC(C)CNC(=S)N1CCN(CC1)c1ccc(cc1)N(Cc1cnc[nH]1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C25H32N6O2S2/c1-20(2)16-27-25(34)30-14-12-29(13-15-30)22-8-10-23(11-9-22)31(18-21-17-26-19-28-21)35(32,33)24-6-4-3-5-7-24/h3-11,17,19-20H,12-16,18H2,1-2H3,(H,26,28)(H,27,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre Fabre Curated by ChEMBL					Assay Description Inhibit of purified bovine Farnesyl protein transferase.				Bioorg Med Chem Lett 13: 1455-8 (2003) BindingDB Entry DOI: 10.7270/Q2NV9JSG
					More data for this Ligand-Target Pair
Squalene synthase (Rattus norvegicus)	BDBM50031839 (((E)-6,10-Dimethyl-1-phosphono-undeca-5,9-dienyl)-...) Show SMILES [#6]\[#6](-[#6])=[#6]/[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6]-[#6](P([#8])([#8])=O)P([#8])([#8])=O Show InChI InChI=1S/C13H26O6P2/c1-11(2)7-6-9-12(3)8-4-5-10-13(20(14,15)16)21(17,18)19/h7-8,13H,4-6,9-10H2,1-3H3,(H2,14,15,16)(H2,17,18,19)/b12-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of squalene synthase from rat liver microsomes				Bioorg Med Chem Lett 6: 1291-1296 (1996) Article DOI: 10.1016/0960-894X(96)00238-7 BindingDB Entry DOI: 10.7270/Q2ZC82TQ
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50126540 (4-{4-[Benzenesulfonyl-(3H-imidazol-4-ylmethyl)-ami...) Show SMILES O=S(=O)(N(Cc1cnc[nH]1)c1ccc(cc1)N1CCN(CC1)C(=S)NC1CCCCC1)c1ccccc1 Show InChI InChI=1S/C27H34N6O2S2/c34-37(35,26-9-5-2-6-10-26)33(20-23-19-28-21-29-23)25-13-11-24(12-14-25)31-15-17-32(18-16-31)27(36)30-22-7-3-1-4-8-22/h2,5-6,9-14,19,21-22H,1,3-4,7-8,15-18,20H2,(H,28,29)(H,30,36)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre Fabre Curated by ChEMBL					Assay Description Inhibit of purified bovine Farnesyl protein transferase.				Bioorg Med Chem Lett 13: 1455-8 (2003) BindingDB Entry DOI: 10.7270/Q2NV9JSG
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50126552 (4-(5-{[{4-[4-(5-Chloro-thiophene-2-carbonyl)-piper...) Show SMILES Fc1cccc(CN(Cc2cncn2Cc2ccc(cc2)C#N)c2ccc(cc2)N2CCN(CC2)C(=O)c2ccc(Cl)s2)c1 Show InChI InChI=1S/C34H30ClFN6OS/c35-33-13-12-32(44-33)34(43)40-16-14-39(15-17-40)29-8-10-30(11-9-29)41(22-27-2-1-3-28(36)18-27)23-31-20-38-24-42(31)21-26-6-4-25(19-37)5-7-26/h1-13,18,20,24H,14-17,21-23H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre Fabre Curated by ChEMBL					Assay Description Inhibit of purified bovine Farnesyl protein transferase.				Bioorg Med Chem Lett 13: 1455-8 (2003) BindingDB Entry DOI: 10.7270/Q2NV9JSG
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50126543 (4-{4-[Benzenesulfonyl-(3H-imidazol-4-ylmethyl)-ami...) Show SMILES O=S(=O)(N(Cc1cnc[nH]1)c1ccc(cc1)N1CCN(CC1)C(=S)NCC1CCCCC1)c1ccccc1 Show InChI InChI=1S/C28H36N6O2S2/c35-38(36,27-9-5-2-6-10-27)34(21-24-20-29-22-31-24)26-13-11-25(12-14-26)32-15-17-33(18-16-32)28(37)30-19-23-7-3-1-4-8-23/h2,5-6,9-14,20,22-23H,1,3-4,7-8,15-19,21H2,(H,29,31)(H,30,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre Fabre Curated by ChEMBL					Assay Description Inhibit of purified bovine Farnesyl protein transferase.				Bioorg Med Chem Lett 13: 1455-8 (2003) BindingDB Entry DOI: 10.7270/Q2NV9JSG
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50126560 ((4E,8E)-2-{Benzenesulfonyl-[3-(4-cyano-benzyl)-3H-...) Show SMILES [#6]\[#6](-[#6])=[#6]/[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6](-[#7](-[#6]-c1cncn1-[#6]-c1ccc(cc1)C#N)S(=O)(=O)c1ccccc1)-[#6](=O)-[#7]-[#6]-c1ccccc1 Show InChI InChI=1S/C42H49N5O3S/c1-33(2)13-11-14-34(3)15-12-16-35(4)21-26-41(42(48)45-28-37-17-7-5-8-18-37)47(51(49,50)40-19-9-6-10-20-40)31-39-29-44-32-46(39)30-38-24-22-36(27-43)23-25-38/h5-10,13,15,17-25,29,32,41H,11-12,14,16,26,28,30-31H2,1-4H3,(H,45,48)/b34-15+,35-21+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre Fabre Curated by ChEMBL					Assay Description In vitro inhibition of bovine Farnesyl transferase				Bioorg Med Chem Lett 13: 1459-62 (2003) BindingDB Entry DOI: 10.7270/Q2TX3DSS
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50126555 (4-{4-[Benzenesulfonyl-(3H-imidazol-4-ylmethyl)-ami...) Show SMILES O=S(=O)(N(Cc1cnc[nH]1)c1ccc(cc1)N1CCN(CC1)C(=S)NCc1ccccc1)c1ccccc1 Show InChI InChI=1S/C28H30N6O2S2/c35-38(36,27-9-5-2-6-10-27)34(21-24-20-29-22-31-24)26-13-11-25(12-14-26)32-15-17-33(18-16-32)28(37)30-19-23-7-3-1-4-8-23/h1-14,20,22H,15-19,21H2,(H,29,31)(H,30,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre Fabre Curated by ChEMBL					Assay Description Inhibit of purified bovine Farnesyl protein transferase.				Bioorg Med Chem Lett 13: 1455-8 (2003) BindingDB Entry DOI: 10.7270/Q2NV9JSG
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50126544 (4-(5-{[{4-[4-(5-Chloro-thiophene-2-carbonyl)-piper...) Show SMILES Fc1ccc(CN(Cc2cncn2Cc2ccc(cc2)C#N)c2ccc(cc2)N2CCN(CC2)C(=O)c2ccc(Cl)s2)cc1 Show InChI InChI=1S/C34H30ClFN6OS/c35-33-14-13-32(44-33)34(43)40-17-15-39(16-18-40)29-9-11-30(12-10-29)41(21-27-5-7-28(36)8-6-27)23-31-20-38-24-42(31)22-26-3-1-25(19-37)2-4-26/h1-14,20,24H,15-18,21-23H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre Fabre Curated by ChEMBL					Assay Description Inhibit of purified bovine Farnesyl protein transferase.				Bioorg Med Chem Lett 13: 1455-8 (2003) BindingDB Entry DOI: 10.7270/Q2NV9JSG
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50126558 (4-[5-({4-[4-(5-Chloro-thiophene-2-carbonyl)-pipera...) Show SMILES Clc1ccc(s1)C(=O)N1CCN(CC1)c1ccc(NCc2cncn2Cc2ccc(cc2)C#N)cc1 Show InChI InChI=1S/C27H25ClN6OS/c28-26-10-9-25(36-26)27(35)33-13-11-32(12-14-33)23-7-5-22(6-8-23)31-17-24-16-30-19-34(24)18-21-3-1-20(15-29)2-4-21/h1-10,16,19,31H,11-14,17-18H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre Fabre Curated by ChEMBL					Assay Description Inhibit of purified bovine Farnesyl protein transferase.				Bioorg Med Chem Lett 13: 1455-8 (2003) BindingDB Entry DOI: 10.7270/Q2NV9JSG
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50059875 ((S)-3-Phenyl-2-((4E,8E)-5,9,13-trimethyl-2-phospho...) Show SMILES [#6]-[#6](-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#6]-[#6]=[#6](-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](-[#8])=O)P([#8])([#8])=O |w:14.13| Show InChI InChI=1S/C26H38NO6P/c1-19(2)10-8-11-20(3)12-9-13-21(4)16-17-24(34(31,32)33)25(28)27-23(26(29)30)18-22-14-6-5-7-15-22/h5-7,10,12,14-15,17,21,23H,8-9,11,13,16,18H2,1-4H3,(H,27,28)(H,29,30)(H2,31,32,33)/b20-12+,24-17?/t21?,23-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of farnesyl protein transferase from bovine brain				Bioorg Med Chem Lett 6: 1291-1296 (1996) Article DOI: 10.1016/0960-894X(96)00238-7 BindingDB Entry DOI: 10.7270/Q2ZC82TQ
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50059875 ((S)-3-Phenyl-2-((4E,8E)-5,9,13-trimethyl-2-phospho...) Show SMILES [#6]-[#6](-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#6]-[#6]=[#6](-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](-[#8])=O)P([#8])([#8])=O |w:14.13| Show InChI InChI=1S/C26H38NO6P/c1-19(2)10-8-11-20(3)12-9-13-21(4)16-17-24(34(31,32)33)25(28)27-23(26(29)30)18-22-14-6-5-7-15-22/h5-7,10,12,14-15,17,21,23H,8-9,11,13,16,18H2,1-4H3,(H,27,28)(H,29,30)(H2,31,32,33)/b20-12+,24-17?/t21?,23-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre Fabre Curated by ChEMBL					Assay Description In vitro inhibition of bovine Farnesyl transferase				Bioorg Med Chem Lett 13: 1459-62 (2003) BindingDB Entry DOI: 10.7270/Q2TX3DSS
					More data for this Ligand-Target Pair
Squalene synthase (Rattus norvegicus)	BDBM50287113 ((S)-3-Phenyl-2-((4E,8E)-5,9,13-trimethyl-2-phospho...) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6](-[#6])=[#6]-[#6]-[#6](-[#6]P([#8])([#8])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](-[#8])=O |w:13.13| Show InChI InChI=1S/C27H40NO6P/c1-20(2)10-8-11-21(3)12-9-13-22(4)16-17-24(19-35(32,33)34)26(29)28-25(27(30)31)18-23-14-6-5-7-15-23/h5-7,10,12,14-16,24-25H,8-9,11,13,17-19H2,1-4H3,(H,28,29)(H,30,31)(H2,32,33,34)/b21-12+,22-16?/t24?,25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of squalene synthase from rat liver microsomes				Bioorg Med Chem Lett 6: 1291-1296 (1996) Article DOI: 10.1016/0960-894X(96)00238-7 BindingDB Entry DOI: 10.7270/Q2ZC82TQ
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50126565 ((S)-2-((4E,8E)-2-{[3-(4-Cyano-benzyl)-3H-imidazol-...) Show SMILES [#6]\[#6](-[#6])=[#6]/[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6](-[#7]-[#6]-c1cncn1-[#6]-c1ccc(cc1)C#N)-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](-[#8])=O Show InChI InChI=1S/C38H47N5O3/c1-28(2)10-8-11-29(3)12-9-13-30(4)16-21-35(37(44)42-36(38(45)46)22-31-14-6-5-7-15-31)41-25-34-24-40-27-43(34)26-33-19-17-32(23-39)18-20-33/h5-7,10,12,14-20,24,27,35-36,41H,8-9,11,13,21-22,25-26H2,1-4H3,(H,42,44)(H,45,46)/b29-12+,30-16+/t35?,36-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	91	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre Fabre Curated by ChEMBL					Assay Description In vitro inhibition of bovine Farnesyl transferase				Bioorg Med Chem Lett 13: 1459-62 (2003) BindingDB Entry DOI: 10.7270/Q2TX3DSS
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50126548 (4-{4-[Benzenesulfonyl-(3H-imidazol-4-ylmethyl)-ami...) Show SMILES O=S(=O)(N(Cc1cnc[nH]1)c1ccc(cc1)N1CCN(CC1)C(=S)NCCc1ccccc1)c1ccccc1 Show InChI InChI=1S/C29H32N6O2S2/c36-39(37,28-9-5-2-6-10-28)35(22-25-21-30-23-32-25)27-13-11-26(12-14-27)33-17-19-34(20-18-33)29(38)31-16-15-24-7-3-1-4-8-24/h1-14,21,23H,15-20,22H2,(H,30,32)(H,31,38)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre Fabre Curated by ChEMBL					Assay Description Inhibit of purified bovine Farnesyl protein transferase.				Bioorg Med Chem Lett 13: 1455-8 (2003) BindingDB Entry DOI: 10.7270/Q2NV9JSG
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50287113 ((S)-3-Phenyl-2-((4E,8E)-5,9,13-trimethyl-2-phospho...) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]-[#6](-[#6])=[#6]-[#6]-[#6](-[#6]P([#8])([#8])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](-[#8])=O |w:13.13| Show InChI InChI=1S/C27H40NO6P/c1-20(2)10-8-11-21(3)12-9-13-22(4)16-17-24(19-35(32,33)34)26(29)28-25(27(30)31)18-23-14-6-5-7-15-23/h5-7,10,12,14-16,24-25H,8-9,11,13,17-19H2,1-4H3,(H,28,29)(H,30,31)(H2,32,33,34)/b21-12+,22-16?/t24?,25-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of farnesyl protein transferase from bovine brain				Bioorg Med Chem Lett 6: 1291-1296 (1996) Article DOI: 10.1016/0960-894X(96)00238-7 BindingDB Entry DOI: 10.7270/Q2ZC82TQ
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50126564 (4-{5-[3-Benzyl-2,4-dioxo-5-((2E,6E)-3,7,11-trimeth...) Show SMILES [#6]\[#6](-[#6])=[#6]/[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-c1c(-[#8])n(-[#6]-c2ccccc2)c(=O)n1-[#6]-c1cncn1-[#6]-c1ccc(cc1)C#N Show InChI InChI=1S/C37H43N5O2/c1-28(2)10-8-11-29(3)12-9-13-30(4)16-21-35-36(43)42(25-32-14-6-5-7-15-32)37(44)41(35)26-34-23-39-27-40(34)24-33-19-17-31(22-38)18-20-33/h5-7,10,12,14-20,23,27,43H,8-9,11,13,21,24-26H2,1-4H3/b29-12+,30-16+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre Fabre Curated by ChEMBL					Assay Description In vitro inhibition of bovine Farnesyl transferase				Bioorg Med Chem Lett 13: 1459-62 (2003) BindingDB Entry DOI: 10.7270/Q2TX3DSS
					More data for this Ligand-Target Pair
Squalene synthase (Rattus norvegicus)	BDBM50287115 ((S)-3-Phenyl-2-((5E,9E)-6,10,14-trimethyl-3-phosph...) Show SMILES [#6]-[#6](-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6])-[#6]-[#6]=[#6](-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](-[#8])=O)P([#8])([#8])=O |w:14.13| Show InChI InChI=1S/C27H40NO6P/c1-20(2)10-8-11-21(3)12-9-13-22(4)16-17-24(35(32,33)34)19-26(29)28-25(27(30)31)18-23-14-6-5-7-15-23/h5-7,10,12,14-15,17,22,25H,8-9,11,13,16,18-19H2,1-4H3,(H,28,29)(H,30,31)(H2,32,33,34)/b21-12+,24-17?/t22?,25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of squalene synthase from rat liver microsomes				Bioorg Med Chem Lett 6: 1291-1296 (1996) Article DOI: 10.1016/0960-894X(96)00238-7 BindingDB Entry DOI: 10.7270/Q2ZC82TQ
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50059860 (((2E,6E)-1-Hydroxy-3,7,11-trimethyl-dodeca-2,6,10-...) Show SMILES [#6]-[#6](-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6])-[#6]-[#6](=O)P([#8])([#8])=O Show InChI InChI=1S/C15H27O4P/c1-12(2)7-5-8-13(3)9-6-10-14(4)11-15(16)20(17,18)19/h7,9,14H,5-6,8,10-11H2,1-4H3,(H2,17,18,19)/b13-9+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of farnesyl protein transferase from bovine brain				Bioorg Med Chem Lett 6: 1291-1296 (1996) Article DOI: 10.1016/0960-894X(96)00238-7 BindingDB Entry DOI: 10.7270/Q2ZC82TQ
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50287115 ((S)-3-Phenyl-2-((5E,9E)-6,10,14-trimethyl-3-phosph...) Show SMILES [#6]-[#6](-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6])-[#6]-[#6]=[#6](-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](-[#8])=O)P([#8])([#8])=O |w:14.13| Show InChI InChI=1S/C27H40NO6P/c1-20(2)10-8-11-21(3)12-9-13-22(4)16-17-24(35(32,33)34)19-26(29)28-25(27(30)31)18-23-14-6-5-7-15-23/h5-7,10,12,14-15,17,22,25H,8-9,11,13,16,18-19H2,1-4H3,(H,28,29)(H,30,31)(H2,32,33,34)/b21-12+,24-17?/t22?,25-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of farnesyl protein transferase from bovine brain				Bioorg Med Chem Lett 6: 1291-1296 (1996) Article DOI: 10.1016/0960-894X(96)00238-7 BindingDB Entry DOI: 10.7270/Q2ZC82TQ
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Bos taurus (bovine))	BDBM50126562 ((S)-2-{(4E,8E)-2-[Benzenesulfonyl-(3-methyl-3H-imi...) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6](-[#7](-[#6]-c1cncn1-[#6])S(=O)(=O)c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](-[#8])=O Show InChI InChI=1S/C37H48N4O5S/c1-28(2)14-12-15-29(3)16-13-17-30(4)22-23-35(36(42)39-34(37(43)44)24-31-18-8-6-9-19-31)41(26-32-25-38-27-40(32)5)47(45,46)33-20-10-7-11-21-33/h6-11,14,16,18-22,25,27,34-35H,12-13,15,17,23-24,26H2,1-5H3,(H,39,42)(H,43,44)/b29-16+,30-22+/t34-,35?/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherche Pierre Fabre Curated by ChEMBL					Assay Description In vitro inhibition of bovine Farnesyl transferase				Bioorg Med Chem Lett 13: 1459-62 (2003) BindingDB Entry DOI: 10.7270/Q2TX3DSS
					More data for this Ligand-Target Pair

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