Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nociceptin receptor (Homo sapiens (Human)) | BDBM50420815 (CHEMBL2088054) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.0373 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assay | J Med Chem 55: 4955-67 (2012) Article DOI: 10.1021/jm201629q BindingDB Entry DOI: 10.7270/Q2TQ62SQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50004193 (CHEMBL3236476) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.0648 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Displacement of [3H]-nociceptin from human recombinant NOP receptor expressed in CHO cells after 60 mins by scintillation counting | J Med Chem 57: 3418-29 (2014) Article DOI: 10.1021/jm500117r BindingDB Entry DOI: 10.7270/Q26Q1ZS0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50420812 (CHEMBL2088061) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.0672 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assay | J Med Chem 55: 4955-67 (2012) Article DOI: 10.1021/jm201629q BindingDB Entry DOI: 10.7270/Q2TQ62SQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50004180 (CHEMBL3236474) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.0711 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Displacement of [3H]-nociceptin from human recombinant NOP receptor expressed in CHO cells after 60 mins by scintillation counting | J Med Chem 57: 3418-29 (2014) Article DOI: 10.1021/jm500117r BindingDB Entry DOI: 10.7270/Q26Q1ZS0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50420804 (CHEMBL2088055) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.0892 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assay | J Med Chem 55: 4955-67 (2012) Article DOI: 10.1021/jm201629q BindingDB Entry DOI: 10.7270/Q2TQ62SQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50400866 (CHEMBL2204348) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.0902 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assay | J Med Chem 55: 4955-67 (2012) Article DOI: 10.1021/jm201629q BindingDB Entry DOI: 10.7270/Q2TQ62SQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50004195 (CHEMBL3236478) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.0908 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Displacement of [3H]-nociceptin from human recombinant NOP receptor expressed in CHO cells after 60 mins by scintillation counting | J Med Chem 57: 3418-29 (2014) Article DOI: 10.1021/jm500117r BindingDB Entry DOI: 10.7270/Q26Q1ZS0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50004175 (CHEMBL3236486) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.0916 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Displacement of [3H]-nociceptin from human recombinant NOP receptor expressed in CHO cells after 60 mins by scintillation counting | J Med Chem 57: 3418-29 (2014) Article DOI: 10.1021/jm500117r BindingDB Entry DOI: 10.7270/Q26Q1ZS0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50004196 (CHEMBL3236479) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.0939 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Displacement of [3H]-nociceptin from human recombinant NOP receptor expressed in CHO cells after 60 mins by scintillation counting | J Med Chem 57: 3418-29 (2014) Article DOI: 10.1021/jm500117r BindingDB Entry DOI: 10.7270/Q26Q1ZS0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50004181 (CHEMBL3236475) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.0954 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Displacement of [3H]-nociceptin from human recombinant NOP receptor expressed in CHO cells after 60 mins by scintillation counting | J Med Chem 57: 3418-29 (2014) Article DOI: 10.1021/jm500117r BindingDB Entry DOI: 10.7270/Q26Q1ZS0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50004174 (CHEMBL3236485) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.0970 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Displacement of [3H]-nociceptin from human recombinant NOP receptor expressed in CHO cells after 60 mins by scintillation counting | J Med Chem 57: 3418-29 (2014) Article DOI: 10.1021/jm500117r BindingDB Entry DOI: 10.7270/Q26Q1ZS0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50004176 (CHEMBL3236487) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.105 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Displacement of [3H]-nociceptin from human recombinant NOP receptor expressed in CHO cells after 60 mins by scintillation counting | J Med Chem 57: 3418-29 (2014) Article DOI: 10.1021/jm500117r BindingDB Entry DOI: 10.7270/Q26Q1ZS0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50400874 (CHEMBL2086410) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.106 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assay | J Med Chem 55: 4955-67 (2012) Article DOI: 10.1021/jm201629q BindingDB Entry DOI: 10.7270/Q2TQ62SQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50420810 (CHEMBL2088060) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.114 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assay | J Med Chem 55: 4955-67 (2012) Article DOI: 10.1021/jm201629q BindingDB Entry DOI: 10.7270/Q2TQ62SQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50004173 (CHEMBL3236484) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.114 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Displacement of [3H]-nociceptin from human recombinant NOP receptor expressed in CHO cells after 60 mins by scintillation counting | J Med Chem 57: 3418-29 (2014) Article DOI: 10.1021/jm500117r BindingDB Entry DOI: 10.7270/Q26Q1ZS0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50004194 (CHEMBL3236477) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.122 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Displacement of [3H]-nociceptin from human recombinant NOP receptor expressed in CHO cells after 60 mins by scintillation counting | J Med Chem 57: 3418-29 (2014) Article DOI: 10.1021/jm500117r BindingDB Entry DOI: 10.7270/Q26Q1ZS0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50420816 (CHEMBL2088053) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.124 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assay | J Med Chem 55: 4955-67 (2012) Article DOI: 10.1021/jm201629q BindingDB Entry DOI: 10.7270/Q2TQ62SQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50420814 (CHEMBL2088056) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.127 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assay | J Med Chem 55: 4955-67 (2012) Article DOI: 10.1021/jm201629q BindingDB Entry DOI: 10.7270/Q2TQ62SQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50420803 (CHEMBL2088057) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.134 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assay | J Med Chem 55: 4955-67 (2012) Article DOI: 10.1021/jm201629q BindingDB Entry DOI: 10.7270/Q2TQ62SQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50400873 (CHEMBL2088029) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.137 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assay | J Med Chem 55: 4955-67 (2012) Article DOI: 10.1021/jm201629q BindingDB Entry DOI: 10.7270/Q2TQ62SQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50004179 (CHEMBL3236473) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.139 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Displacement of [3H]-nociceptin from human recombinant NOP receptor expressed in CHO cells after 60 mins by scintillation counting | J Med Chem 57: 3418-29 (2014) Article DOI: 10.1021/jm500117r BindingDB Entry DOI: 10.7270/Q26Q1ZS0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50004166 (CHEMBL3236482) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.145 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Displacement of [3H]-nociceptin from human recombinant NOP receptor expressed in CHO cells after 60 mins by scintillation counting | J Med Chem 57: 3418-29 (2014) Article DOI: 10.1021/jm500117r BindingDB Entry DOI: 10.7270/Q26Q1ZS0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50420805 (CHEMBL2088052) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.169 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assay | J Med Chem 55: 4955-67 (2012) Article DOI: 10.1021/jm201629q BindingDB Entry DOI: 10.7270/Q2TQ62SQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50004144 (CHEMBL3236480) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.172 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Displacement of [3H]-nociceptin from human recombinant NOP receptor expressed in CHO cells after 60 mins by scintillation counting | J Med Chem 57: 3418-29 (2014) Article DOI: 10.1021/jm500117r BindingDB Entry DOI: 10.7270/Q26Q1ZS0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50400872 (CHEMBL2088033) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.174 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assay | J Med Chem 55: 4955-67 (2012) Article DOI: 10.1021/jm201629q BindingDB Entry DOI: 10.7270/Q2TQ62SQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50004161 (CHEMBL3236481) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.176 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Displacement of [3H]-nociceptin from human recombinant NOP receptor expressed in CHO cells after 60 mins by scintillation counting | J Med Chem 57: 3418-29 (2014) Article DOI: 10.1021/jm500117r BindingDB Entry DOI: 10.7270/Q26Q1ZS0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50004177 (CHEMBL3236488) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.185 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Displacement of [3H]-nociceptin from human recombinant NOP receptor expressed in CHO cells after 60 mins by scintillation counting | J Med Chem 57: 3418-29 (2014) Article DOI: 10.1021/jm500117r BindingDB Entry DOI: 10.7270/Q26Q1ZS0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50420811 (CHEMBL2088062) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.194 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assay | J Med Chem 55: 4955-67 (2012) Article DOI: 10.1021/jm201629q BindingDB Entry DOI: 10.7270/Q2TQ62SQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50004178 (Nociceptin | Nociceptin/orphanin FQ | ORPHANIN FQ) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | 0.214 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Displacement of [3H]-nociceptin from human recombinant NOP receptor expressed in CHO cells after 60 mins by scintillation counting | J Med Chem 57: 3418-29 (2014) Article DOI: 10.1021/jm500117r BindingDB Entry DOI: 10.7270/Q26Q1ZS0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50400871 (CHEMBL2088030) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.231 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assay | J Med Chem 55: 4955-67 (2012) Article DOI: 10.1021/jm201629q BindingDB Entry DOI: 10.7270/Q2TQ62SQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50420817 (CHEMBL2088051) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.248 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assay | J Med Chem 55: 4955-67 (2012) Article DOI: 10.1021/jm201629q BindingDB Entry DOI: 10.7270/Q2TQ62SQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50400870 (CHEMBL559569 | SB-612111) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 0.253 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assay | J Med Chem 55: 4955-67 (2012) Article DOI: 10.1021/jm201629q BindingDB Entry DOI: 10.7270/Q2TQ62SQ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50420801 (CHEMBL2088035) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem | Article PubMed | 0.336 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Displacement of [3H]Nociceptin from human recombinant NOP receptor expressed in CHO cells by scintillation counter | J Med Chem 55: 4955-67 (2012) Article DOI: 10.1021/jm201629q BindingDB Entry DOI: 10.7270/Q2TQ62SQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50004171 (CHEMBL3236483) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.371 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Displacement of [3H]-nociceptin from human recombinant NOP receptor expressed in CHO cells after 60 mins by scintillation counting | J Med Chem 57: 3418-29 (2014) Article DOI: 10.1021/jm500117r BindingDB Entry DOI: 10.7270/Q26Q1ZS0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50420813 (CHEMBL2088059) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.396 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assay | J Med Chem 55: 4955-67 (2012) Article DOI: 10.1021/jm201629q BindingDB Entry DOI: 10.7270/Q2TQ62SQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50083230 (1-((3R,4R)-1-Cyclooctylmethyl-3-hydroxymethyl-pipe...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 0.403 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assay | J Med Chem 55: 4955-67 (2012) Article DOI: 10.1021/jm201629q BindingDB Entry DOI: 10.7270/Q2TQ62SQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50420808 (CHEMBL2088041 | CHEMBL2088042) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.458 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assay | J Med Chem 55: 4955-67 (2012) Article DOI: 10.1021/jm201629q BindingDB Entry DOI: 10.7270/Q2TQ62SQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50420808 (CHEMBL2088041 | CHEMBL2088042) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.458 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Displacement of [3H]Nociceptin from human recombinant NOP receptor expressed in CHO cells by scintillation counter | J Med Chem 55: 4955-67 (2012) Article DOI: 10.1021/jm201629q BindingDB Entry DOI: 10.7270/Q2TQ62SQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50420802 (CHEMBL2088034) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Displacement of [3H]Nociceptin from human recombinant NOP receptor expressed in CHO cells by scintillation counter | J Med Chem 55: 4955-67 (2012) Article DOI: 10.1021/jm201629q BindingDB Entry DOI: 10.7270/Q2TQ62SQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50420799 (CHEMBL2088037) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assay | J Med Chem 55: 4955-67 (2012) Article DOI: 10.1021/jm201629q BindingDB Entry DOI: 10.7270/Q2TQ62SQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50420808 (CHEMBL2088041 | CHEMBL2088042) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Displacement of [3H]Nociceptin from human recombinant NOP receptor expressed in CHO cells by scintillation counter | J Med Chem 55: 4955-67 (2012) Article DOI: 10.1021/jm201629q BindingDB Entry DOI: 10.7270/Q2TQ62SQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human)) | BDBM50140256 (CHEMBL3740223) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company Curated by ChEMBL | Assay Description Antagonist activity at human EP4 receptor | Bioorg Med Chem Lett 26: 105-9 (2016) Article DOI: 10.1016/j.bmcl.2015.11.023 BindingDB Entry DOI: 10.7270/Q2G73HRK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50420809 (CHEMBL2088038 | CHEMBL2088039) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.05 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Displacement of [3H]Nociceptin from human recombinant NOP receptor expressed in CHO cells by scintillation counter | J Med Chem 55: 4955-67 (2012) Article DOI: 10.1021/jm201629q BindingDB Entry DOI: 10.7270/Q2TQ62SQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human)) | BDBM50140258 (CHEMBL3740325) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company Curated by ChEMBL | Assay Description Antagonist activity at human EP4 receptor | Bioorg Med Chem Lett 26: 105-9 (2016) Article DOI: 10.1016/j.bmcl.2015.11.023 BindingDB Entry DOI: 10.7270/Q2G73HRK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human)) | BDBM50499955 (CHEMBL3741430) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company Curated by ChEMBL | Assay Description Antagonist activity at human EP4 receptor | Bioorg Med Chem Lett 26: 105-9 (2016) Article DOI: 10.1016/j.bmcl.2015.11.023 BindingDB Entry DOI: 10.7270/Q2G73HRK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50400869 (CHEMBL2088031) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assay | J Med Chem 55: 4955-67 (2012) Article DOI: 10.1021/jm201629q BindingDB Entry DOI: 10.7270/Q2TQ62SQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50420807 (CHEMBL2088043) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assay | J Med Chem 55: 4955-67 (2012) Article DOI: 10.1021/jm201629q BindingDB Entry DOI: 10.7270/Q2TQ62SQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50400868 (CHEMBL2204349) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assay | J Med Chem 55: 4955-67 (2012) Article DOI: 10.1021/jm201629q BindingDB Entry DOI: 10.7270/Q2TQ62SQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Nociceptin receptor (Homo sapiens (Human)) | BDBM50400867 (CHEMBL2088032) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigaci�n Lilly Curated by ChEMBL | Assay Description Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assay | J Med Chem 55: 4955-67 (2012) Article DOI: 10.1021/jm201629q BindingDB Entry DOI: 10.7270/Q2TQ62SQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human)) | BDBM50499950 (CHEMBL3739435) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 6.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Eli Lilly and Company Curated by ChEMBL | Assay Description Antagonist activity at human EP4 receptor | Bioorg Med Chem Lett 26: 105-9 (2016) Article DOI: 10.1016/j.bmcl.2015.11.023 BindingDB Entry DOI: 10.7270/Q2G73HRK | |||||||||||
More data for this Ligand-Target Pair |
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