Found 5 hits with Last Name = 'nickelsen' and Initial = 'a' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Casein kinase II subunit alpha'/beta
(Homo sapiens (Human)) | BDBM50530315
(CHEMBL4520531)Show InChI InChI=1S/C20H14N2O3S/c23-18-10-15(7-8-16(18)19(24)25)21-20-22-17(11-26-20)14-6-5-12-3-1-2-4-13(12)9-14/h1-11,23H,(H,21,22)(H,24,25) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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PC cid PC sid PDB UniChem
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| 86 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£t zu K£ln
Curated by ChEMBL
| Assay Description ATP competitive inhibition of recombinant human CK2alpha2 (1 to 335 residues)/CK2beta2 (1 to 193 residues) expressed in Escherichia coli BL21(DE3) us... |
J Med Chem 63: 7766-7772 (2020)
Article DOI: 10.1021/acs.jmedchem.0c00587 BindingDB Entry DOI: 10.7270/Q24M9834 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Casein kinase II subunit alpha'/beta
(Homo sapiens (Human)) | BDBM50540033
(CHEMBL4635554)Show InChI InChI=1S/C16H11ClN2O3S/c17-10-3-1-9(2-4-10)13-8-23-16(19-13)18-11-5-6-12(15(21)22)14(20)7-11/h1-8,20H,(H,18,19)(H,21,22) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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PC cid PC sid PDB UniChem
| PDB Article PubMed
| 206 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£t zu K£ln
Curated by ChEMBL
| Assay Description ATP competitive inhibition of recombinant human CK2alpha2 (1 to 335 residues)/CK2beta2 (1 to 193 residues) expressed in Escherichia coli BL21(DE3) us... |
J Med Chem 63: 7766-7772 (2020)
Article DOI: 10.1021/acs.jmedchem.0c00587 BindingDB Entry DOI: 10.7270/Q24M9834 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Casein kinase II subunit alpha'/beta
(Homo sapiens (Human)) | BDBM50540034
(CHEMBL4647986)Show InChI InChI=1S/C15H11N3O2S/c19-14(20)10-4-3-5-11(8-10)17-15-18-13(9-21-15)12-6-1-2-7-16-12/h1-9H,(H,17,18)(H,19,20) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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PC cid PC sid PDB UniChem
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| 1.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£t zu K£ln
Curated by ChEMBL
| Assay Description ATP competitive inhibition of recombinant human CK2alpha2 (1 to 335 residues)/CK2beta2 (1 to 193 residues) expressed in Escherichia coli BL21(DE3) us... |
J Med Chem 63: 7766-7772 (2020)
Article DOI: 10.1021/acs.jmedchem.0c00587 BindingDB Entry DOI: 10.7270/Q24M9834 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Casein kinase II subunit alpha
(Homo sapiens (Human)) | BDBM50252622
(CHEMBL4070389)Show SMILES OC(=O)c1cccc(NC(=O)CCNC(=O)CCNCc2ccc(c(Cl)c2)-c2ccccc2)c1 Show InChI InChI=1S/C26H26ClN3O4/c27-23-15-18(9-10-22(23)19-5-2-1-3-6-19)17-28-13-11-24(31)29-14-12-25(32)30-21-8-4-7-20(16-21)26(33)34/h1-10,15-16,28H,11-14,17H2,(H,29,31)(H,30,32)(H,33,34) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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PC cid PC sid PDB UniChem
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| n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00063 BindingDB Entry DOI: 10.7270/Q2ZP4B53 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Casein kinase I isoform epsilon
(Homo sapiens (Human)) | BDBM50602484
(CHEMBL5195963)Show SMILES Clc1ccc(CCNC(=O)CCC(=O)NCCCCn2cnc3c(Br)c(Br)c(Br)c(Br)c23)cc1Cl | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
| Article PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00063 BindingDB Entry DOI: 10.7270/Q2ZP4B53 |
More data for this Ligand-Target Pair | |