Found 259 hits with Last Name = 'petronzi' and Initial = 'c' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078888
(CHEMBL3416359)Show SMILES CCCCCCCCCCCCC1=C(OC)C(OC)=CC(=O)C1=O |c:12,18| Show InChI InChI=1S/C20H32O4/c1-4-5-6-7-8-9-10-11-12-13-14-16-19(22)17(21)15-18(23-2)20(16)24-3/h15H,4-14H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation pre-incubated for 15 mins followed... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078886
(CHEMBL3416361)Show SMILES CCCCCCCCCCCCCCC1=C(OC)C(OC)=CC(=O)C1=O |c:14,20| Show InChI InChI=1S/C22H36O4/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-18-21(24)19(23)17-20(25-2)22(18)26-3/h17H,4-16H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078890
(CHEMBL3416357)Show SMILES CCCCCCCCCCC1=C(OC)C(OC)=CC(=O)C1=O |c:10,16| Show InChI InChI=1S/C18H28O4/c1-4-5-6-7-8-9-10-11-12-14-17(20)15(19)13-16(21-2)18(14)22-3/h13H,4-12H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation pre-incubated for 15 mins followed... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078887
(CHEMBL3416360)Show SMILES CCCCCCCCCCCCCC1=C(OC)C(OC)=CC(=O)C1=O |c:13,19| Show InChI InChI=1S/C21H34O4/c1-4-5-6-7-8-9-10-11-12-13-14-15-17-20(23)18(22)16-19(24-2)21(17)25-3/h16H,4-15H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation in presence of arachidonic acid pr... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078889
(CHEMBL3416358)Show SMILES CCCCCCCCCCCC1=C(OC)C(OC)=CC(=O)C1=O |c:11,17| Show InChI InChI=1S/C19H30O4/c1-4-5-6-7-8-9-10-11-12-13-15-18(21)16(20)14-17(22-2)19(15)23-3/h14H,4-13H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation pre-incubated for 15 mins followed... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078850
(CHEBI:4778 | Embelin)Show SMILES CCCCCCCCCCCC1=C(O)C(=O)C=C(O)C1=O |c:11,t:16| Show InChI InChI=1S/C17H26O4/c1-2-3-4-5-6-7-8-9-10-11-13-16(20)14(18)12-15(19)17(13)21/h12,18,21H,2-11H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
MCE KEGG PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of human 5-LOX by cell free assay |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078850
(CHEBI:4778 | Embelin)Show SMILES CCCCCCCCCCCC1=C(O)C(=O)C=C(O)C1=O |c:11,t:16| Show InChI InChI=1S/C17H26O4/c1-2-3-4-5-6-7-8-9-10-11-13-16(20)14(18)12-15(19)17(13)21/h12,18,21H,2-11H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
MCE KEGG PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078890
(CHEMBL3416357)Show SMILES CCCCCCCCCCC1=C(OC)C(OC)=CC(=O)C1=O |c:10,16| Show InChI InChI=1S/C18H28O4/c1-4-5-6-7-8-9-10-11-12-14-17(20)15(19)13-16(21-2)18(14)22-3/h13H,4-12H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation in presence of arachidonic acid pr... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078887
(CHEMBL3416360)Show SMILES CCCCCCCCCCCCCC1=C(OC)C(OC)=CC(=O)C1=O |c:13,19| Show InChI InChI=1S/C21H34O4/c1-4-5-6-7-8-9-10-11-12-13-14-15-17-20(23)18(22)16-19(24-2)21(17)25-3/h16H,4-15H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078886
(CHEMBL3416361)Show SMILES CCCCCCCCCCCCCCC1=C(OC)C(OC)=CC(=O)C1=O |c:14,20| Show InChI InChI=1S/C22H36O4/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-18-21(24)19(23)17-20(25-2)22(18)26-3/h17H,4-16H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation in presence of arachidonic acid pr... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078889
(CHEMBL3416358)Show SMILES CCCCCCCCCCCC1=C(OC)C(OC)=CC(=O)C1=O |c:11,17| Show InChI InChI=1S/C19H30O4/c1-4-5-6-7-8-9-10-11-12-13-15-18(21)16(20)14-17(22-2)19(15)23-3/h14H,4-13H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078883
(CHEMBL3416365)Show SMILES [#6]-[#8]-[#6]-1=[#6]-[#6](=O)-[#6](=O)-[#6](-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])=[#6]-1-[#8]-[#6] |c:23,t:2| Show InChI InChI=1S/C23H32O4/c1-16(2)9-7-10-17(3)11-8-12-18(4)13-14-19-22(25)20(24)15-21(26-5)23(19)27-6/h9,11,13,15H,7-8,10,12,14H2,1-6H3/b17-11+,18-13+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation in presence of arachidonic acid pr... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078889
(CHEMBL3416358)Show SMILES CCCCCCCCCCCC1=C(OC)C(OC)=CC(=O)C1=O |c:11,17| Show InChI InChI=1S/C19H30O4/c1-4-5-6-7-8-9-10-11-12-13-15-18(21)16(20)14-17(22-2)19(15)23-3/h14H,4-13H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation in presence of arachidonic acid pr... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078887
(CHEMBL3416360)Show SMILES CCCCCCCCCCCCCC1=C(OC)C(OC)=CC(=O)C1=O |c:13,19| Show InChI InChI=1S/C21H34O4/c1-4-5-6-7-8-9-10-11-12-13-14-15-17-20(23)18(22)16-19(24-2)21(17)25-3/h16H,4-15H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation pre-incubated for 15 mins followed... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078886
(CHEMBL3416361)Show SMILES CCCCCCCCCCCCCCC1=C(OC)C(OC)=CC(=O)C1=O |c:14,20| Show InChI InChI=1S/C22H36O4/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-18-21(24)19(23)17-20(25-2)22(18)26-3/h17H,4-16H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation pre-incubated for 15 mins followed... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078888
(CHEMBL3416359)Show SMILES CCCCCCCCCCCCC1=C(OC)C(OC)=CC(=O)C1=O |c:12,18| Show InChI InChI=1S/C20H32O4/c1-4-5-6-7-8-9-10-11-12-13-14-16-19(22)17(21)15-18(23-2)20(16)24-3/h15H,4-14H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078890
(CHEMBL3416357)Show SMILES CCCCCCCCCCC1=C(OC)C(OC)=CC(=O)C1=O |c:10,16| Show InChI InChI=1S/C18H28O4/c1-4-5-6-7-8-9-10-11-12-14-17(20)15(19)13-16(21-2)18(14)22-3/h13H,4-12H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078888
(CHEMBL3416359)Show SMILES CCCCCCCCCCCCC1=C(OC)C(OC)=CC(=O)C1=O |c:12,18| Show InChI InChI=1S/C20H32O4/c1-4-5-6-7-8-9-10-11-12-13-14-16-19(22)17(21)15-18(23-2)20(16)24-3/h15H,4-14H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation in presence of arachidonic acid pr... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078883
(CHEMBL3416365)Show SMILES [#6]-[#8]-[#6]-1=[#6]-[#6](=O)-[#6](=O)-[#6](-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])=[#6]-1-[#8]-[#6] |c:23,t:2| Show InChI InChI=1S/C23H32O4/c1-16(2)9-7-10-17(3)11-8-12-18(4)13-14-19-22(25)20(24)15-21(26-5)23(19)27-6/h9,11,13,15H,7-8,10,12,14H2,1-6H3/b17-11+,18-13+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation pre-incubated for 15 mins followed... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078847
(CHEMBL3416165)Show SMILES CCCCCCCCCCCCCCC1=C(O)C(=O)C=C(O)C1=O |c:14,t:19| Show InChI InChI=1S/C20H32O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19(23)17(21)15-18(22)20(16)24/h15,21,24H,2-14H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078849
(CHEMBL3416164)Show SMILES CCCCCCCCCCCCC1=C(O)C(=O)C=C(O)C1=O |c:12,t:17| Show InChI InChI=1S/C18H28O4/c1-2-3-4-5-6-7-8-9-10-11-12-14-17(21)15(19)13-16(20)18(14)22/h13,19,22H,2-12H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078851
(CHEMBL3416163)Show SMILES CCCCCCCCCCC1=C(O)C(=O)C=C(O)C1=O |c:10,t:15| Show InChI InChI=1S/C16H24O4/c1-2-3-4-5-6-7-8-9-10-12-15(19)13(17)11-14(18)16(12)20/h11,17,20H,2-10H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078881
(CHEMBL3416166)Show SMILES CCCCCCCCCCCCCCCCC1=C(O)C(=O)C=C(O)C1=O |c:16,t:21| Show InChI InChI=1S/C22H36O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-18-21(25)19(23)17-20(24)22(18)26/h17,23,26H,2-16H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078865
(CHEMBL2296071)Show SMILES CCCCCCCCCCCC1=C(OC)C(=O)C=C(OC)C1=O |c:11,t:17| Show InChI InChI=1S/C19H30O4/c1-4-5-6-7-8-9-10-11-12-13-15-18(21)17(22-2)14-16(20)19(15)23-3/h14H,4-13H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation pre-incubated for 15 mins followed... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Macrophage-expressed gene 1 protein
(Homo sapiens (Human)) | BDBM50078850
(CHEBI:4778 | Embelin)Show SMILES CCCCCCCCCCCC1=C(O)C(=O)C=C(O)C1=O |c:11,t:16| Show InChI InChI=1S/C17H26O4/c1-2-3-4-5-6-7-8-9-10-11-13-16(20)14(18)12-15(19)17(13)21/h12,18,21H,2-11H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
MCE KEGG PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of human mPGES1 |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Macrophage-expressed gene 1 protein
(Homo sapiens (Human)) | BDBM50078850
(CHEBI:4778 | Embelin)Show SMILES CCCCCCCCCCCC1=C(O)C(=O)C=C(O)C1=O |c:11,t:16| Show InChI InChI=1S/C17H26O4/c1-2-3-4-5-6-7-8-9-10-11-13-16(20)14(18)12-15(19)17(13)21/h12,18,21H,2-11H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
MCE KEGG PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of mPGES1 in IL-1beta stimulated human A549 cell microsomal membranes assessed as reduction in PGE2 synthase activity after 15 mins using ... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078868
(CHEMBL3416349)Show SMILES CCCCCCCCCCCCCCC1=C(OC)C(=O)C=C(OC)C1=O |c:14,t:20| Show InChI InChI=1S/C22H36O4/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-18-21(24)20(25-2)17-19(23)22(18)26-3/h17H,4-16H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM22334
(BW A4C | BW4C | BWA4C | BWA4C, 10 | CHEMBL314360 |...)Show InChI InChI=1S/C17H17NO3/c1-14(19)18(20)12-6-8-15-7-5-11-17(13-15)21-16-9-3-2-4-10-16/h2-11,13,20H,12H2,1H3/b8-6+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Salerno
Curated by ChEMBL
| Assay Description Inhibition of 5-LO (unknown origin) |
Eur J Med Chem 67: 269-79 (2013)
Article DOI: 10.1016/j.ejmech.2013.06.039 BindingDB Entry DOI: 10.7270/Q2XW4M9Z |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078848
(CHEBI:8779 | Rapanone)Show SMILES CCCCCCCCCCCCCC1=C(O)C(=O)C=C(O)C1=O |c:13,t:18| Show InChI InChI=1S/C19H30O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-15-18(22)16(20)14-17(21)19(15)23/h14,20,23H,2-13H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
MCE KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078882
(CHEMBL462998)Show SMILES CCCCCCCCCCCCCCCC1=C(O)C(=O)C=C(O)C1=O |c:15,t:20| Show InChI InChI=1S/C21H34O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-17-20(24)18(22)16-19(23)21(17)25/h16,22,25H,2-15H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078867
(CHEMBL3416348)Show SMILES CCCCCCCCCCCCCC1=C(OC)C(=O)C=C(OC)C1=O |c:13,t:19| Show InChI InChI=1S/C21H34O4/c1-4-5-6-7-8-9-10-11-12-13-14-15-17-20(23)19(24-2)16-18(22)21(17)25-3/h16H,4-15H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation pre-incubated for 15 mins followed... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078867
(CHEMBL3416348)Show SMILES CCCCCCCCCCCCCC1=C(OC)C(=O)C=C(OC)C1=O |c:13,t:19| Show InChI InChI=1S/C21H34O4/c1-4-5-6-7-8-9-10-11-12-13-14-15-17-20(23)19(24-2)16-18(22)21(17)25-3/h16H,4-15H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078869
(CHEMBL3416350)Show SMILES CCCCCCCCCCCCCCCC1=C(OC)C(=O)C=C(OC)C1=O |c:15,t:21| Show InChI InChI=1S/C23H38O4/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-19-22(25)21(26-2)18-20(24)23(19)27-3/h18H,4-17H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078856
(CHEMBL2228912)Show SMILES CCCCCCCCCCCCCCC1=C(O)C(=O)C=C(OC)C1=O |c:14,t:19| Show InChI InChI=1S/C21H34O4/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-17-20(23)18(22)16-19(25-2)21(17)24/h16,23H,3-15H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation pre-incubated for 15 mins followed... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078857
(CHEMBL3416174)Show SMILES CCCCCCCCCCCCCCCC1=C(O)C(=O)C=C(OC)C1=O |c:15,t:20| Show InChI InChI=1S/C22H36O4/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-18-21(24)19(23)17-20(26-2)22(18)25/h17,24H,3-16H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50446419
(CHEMBL3109719)Show SMILES COC1=CC(=O)C(Oc2ccc3ccccc3c2)=CC1=O |c:19,t:2| Show InChI InChI=1S/C17H12O4/c1-20-16-9-15(19)17(10-14(16)18)21-13-7-6-11-4-2-3-5-12(11)8-13/h2-10H,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Salerno
Curated by ChEMBL
| Assay Description Inhibition of human recombinant 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate after 10 mins |
Eur J Med Chem 67: 269-79 (2013)
Article DOI: 10.1016/j.ejmech.2013.06.039 BindingDB Entry DOI: 10.7270/Q2XW4M9Z |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078868
(CHEMBL3416349)Show SMILES CCCCCCCCCCCCCCC1=C(OC)C(=O)C=C(OC)C1=O |c:14,t:20| Show InChI InChI=1S/C22H36O4/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-18-21(24)20(25-2)17-19(23)22(18)26-3/h17H,4-16H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 290 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation pre-incubated for 15 mins followed... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM22334
(BW A4C | BW4C | BWA4C | BWA4C, 10 | CHEMBL314360 |...)Show InChI InChI=1S/C17H17NO3/c1-14(19)18(20)12-6-8-15-7-5-11-17(13-15)21-16-9-3-2-4-10-16/h2-11,13,20H,12H2,1H3/b8-6+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Salerno
Curated by ChEMBL
| Assay Description Inhibition of 5-LO (unknown origin) by cell based assay |
Eur J Med Chem 67: 269-79 (2013)
Article DOI: 10.1016/j.ejmech.2013.06.039 BindingDB Entry DOI: 10.7270/Q2XW4M9Z |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078883
(CHEMBL3416365)Show SMILES [#6]-[#8]-[#6]-1=[#6]-[#6](=O)-[#6](=O)-[#6](-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])=[#6]-1-[#8]-[#6] |c:23,t:2| Show InChI InChI=1S/C23H32O4/c1-16(2)9-7-10-17(3)11-8-12-18(4)13-14-19-22(25)20(24)15-21(26-5)23(19)27-6/h9,11,13,15H,7-8,10,12,14H2,1-6H3/b17-11+,18-13+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50446413
(CHEMBL1668217)Show InChI InChI=1S/C17H12O3/c18-15-10-17(20)16(19)9-14(15)8-11-5-6-12-3-1-2-4-13(12)7-11/h1-7,9H,8,10H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Salerno
Curated by ChEMBL
| Assay Description Competitive inhibition of human recombinant 5-LO expressed in Escherichia coli BL21 using 40 uM of arachidonic acid as substrate preincubated for 15 ... |
Eur J Med Chem 67: 269-79 (2013)
Article DOI: 10.1016/j.ejmech.2013.06.039 BindingDB Entry DOI: 10.7270/Q2XW4M9Z |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078867
(CHEMBL3416348)Show SMILES CCCCCCCCCCCCCC1=C(OC)C(=O)C=C(OC)C1=O |c:13,t:19| Show InChI InChI=1S/C21H34O4/c1-4-5-6-7-8-9-10-11-12-13-14-15-17-20(23)19(24-2)16-18(22)21(17)25-3/h16H,4-15H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation in presence of arachidonic acid pr... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078872
(CHEMBL3416353)Show SMILES [#6]-[#8]-[#6]-1=[#6]-[#6](=O)-[#6](-[#8]-[#6])=[#6](-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#6]-1=O |t:2,8| Show InChI InChI=1S/C23H32O4/c1-16(2)9-7-10-17(3)11-8-12-18(4)13-14-19-22(25)21(26-5)15-20(24)23(19)27-6/h9,11,13,15H,7-8,10,12,14H2,1-6H3/b17-11+,18-13+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation pre-incubated for 15 mins followed... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078863
(CHEMBL3416180)Show SMILES CCCCCCCCC1=C(OC)C(=O)C=C(OC)C1=O |c:8,t:14| Show InChI InChI=1S/C16H24O4/c1-4-5-6-7-8-9-10-12-15(18)14(19-2)11-13(17)16(12)20-3/h11H,4-10H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation pre-incubated for 15 mins followed... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078862
(CHEMBL3416179)Show InChI InChI=1S/C14H20O4/c1-4-5-6-7-8-10-13(16)12(17-2)9-11(15)14(10)18-3/h9H,4-8H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation pre-incubated for 15 mins followed... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078874
(CHEMBL3416355)Show InChI InChI=1S/C14H20O4/c1-4-5-6-7-8-10-13(16)11(15)9-12(17-2)14(10)18-3/h9H,4-8H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation pre-incubated for 15 mins followed... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078875
(CHEMBL3416356)Show InChI InChI=1S/C16H24O4/c1-4-5-6-7-8-9-10-12-15(18)13(17)11-14(19-2)16(12)20-3/h11H,4-10H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078884
(CHEMBL3416364)Show SMILES [#6]-[#8]-[#6]-1=[#6]-[#6](=O)-[#6](=O)-[#6](-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])=[#6]-1-[#8]-[#6] |c:18,t:2| Show InChI InChI=1S/C18H24O4/c1-12(2)7-6-8-13(3)9-10-14-17(20)15(19)11-16(21-4)18(14)22-5/h7,9,11H,6,8,10H2,1-5H3/b13-9+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation pre-incubated for 15 mins followed... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078852
(CHEMBL221598)Show InChI InChI=1S/C14H20O4/c1-2-3-4-5-6-7-8-10-13(17)11(15)9-12(16)14(10)18/h9,15,18H,2-8H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078875
(CHEMBL3416356)Show InChI InChI=1S/C16H24O4/c1-4-5-6-7-8-9-10-12-15(18)13(17)11-14(19-2)16(12)20-3/h11H,4-10H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation pre-incubated for 15 mins followed... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50078869
(CHEMBL3416350)Show SMILES CCCCCCCCCCCCCCCC1=C(OC)C(=O)C=C(OC)C1=O |c:15,t:21| Show InChI InChI=1S/C23H38O4/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-19-22(25)21(26-2)18-20(24)23(19)27-3/h18H,4-17H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 390 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples
Curated by ChEMBL
| Assay Description Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation pre-incubated for 15 mins followed... |
Eur J Med Chem 94: 132-9 (2015)
Article DOI: 10.1016/j.ejmech.2015.02.042 BindingDB Entry DOI: 10.7270/Q2T72K5H |
More data for this Ligand-Target Pair | |