Compile Data Set for Download or QSAR

Found 944 hits with Last Name = 'piatnitski' and Initial = 'e'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201397 (1-methyl-N-(3-methyl-4-(trifluoromethyl)phenyl)-4-...) Show SMILES Cc1cc(NC(=O)c2c(NCc3ccncc3)ncn2C)ccc1C(F)(F)F Show InChI InChI=1S/C19H18F3N5O/c1-12-9-14(3-4-15(12)19(20,21)22)26-18(28)16-17(25-11-27(16)2)24-10-13-5-7-23-8-6-13/h3-9,11,24H,10H2,1-2H3,(H,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR2 by [32P]ATP-competitive radioassay				Bioorg Med Chem Lett 17: 1369-75 (2007) Article DOI: 10.1016/j.bmcl.2006.11.087 BindingDB Entry DOI: 10.7270/Q2125S92
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201363 (1-methyl-4-(pyridin-4-ylmethylamino)-N-(4-(trifluo...) Show SMILES Cn1ncc(NCc2ccncc2)c1C(=O)Nc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C18H16F3N5O2/c1-26-16(15(11-24-26)23-10-12-6-8-22-9-7-12)17(27)25-13-2-4-14(5-3-13)28-18(19,20)21/h2-9,11,23H,10H2,1H3,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR2 by [32P]ATP-competitive radioassay				Bioorg Med Chem Lett 17: 1369-75 (2007) Article DOI: 10.1016/j.bmcl.2006.11.087 BindingDB Entry DOI: 10.7270/Q2125S92
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201394 (CHEMBL393779 | N-(4-tert-butylphenyl)-1-methyl-4-(...) Show SMILES Cn1cnc(NCc2ccncc2)c1C(=O)Nc1ccc(cc1)C(C)(C)C Show InChI InChI=1S/C21H25N5O/c1-21(2,3)16-5-7-17(8-6-16)25-20(27)18-19(24-14-26(18)4)23-13-15-9-11-22-12-10-15/h5-12,14,23H,13H2,1-4H3,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR2 by [32P]ATP-competitive radioassay				Bioorg Med Chem Lett 17: 1369-75 (2007) Article DOI: 10.1016/j.bmcl.2006.11.087 BindingDB Entry DOI: 10.7270/Q2125S92
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007606 (CHEMBL3238280) Show SMILES C[C@](O)(COc1ccc(Br)cc1)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C19H17BrN2O3/c1-19(24,12-25-15-7-5-14(20)6-8-15)18(23)22-10-9-16-13(11-21)3-2-4-17(16)22/h2-8,24H,9-10,12H2,1H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007591 (CHEMBL3238292) Show SMILES C[C@](O)(COc1ccc(cc1F)C#N)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C20H16FN3O3/c1-20(26,12-27-18-6-5-13(10-22)9-16(18)21)19(25)24-8-7-15-14(11-23)3-2-4-17(15)24/h2-6,9,26H,7-8,12H2,1H3/t20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007595 (CHEMBL3233069) Show SMILES COc1ccc(OC[C@](C)(O)C(=O)N2CCc3c2cccc3C#N)c(Cl)c1 |r| Show InChI InChI=1S/C20H19ClN2O4/c1-20(25,12-27-18-7-6-14(26-2)10-16(18)21)19(24)23-9-8-15-13(11-22)4-3-5-17(15)23/h3-7,10,25H,8-9,12H2,1-2H3/t20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007590 (CHEMBL3238291) Show SMILES C[C@](O)(COc1ccc(cc1Br)C#N)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C20H16BrN3O3/c1-20(26,12-27-18-6-5-13(10-22)9-16(18)21)19(25)24-8-7-15-14(11-23)3-2-4-17(15)24/h2-6,9,26H,7-8,12H2,1H3/t20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007596 (CHEMBL3233070) Show SMILES C[C@](O)(COc1ccc(Cl)cc1F)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C19H16ClFN2O3/c1-19(25,11-26-17-6-5-13(20)9-15(17)21)18(24)23-8-7-14-12(10-22)3-2-4-16(14)23/h2-6,9,25H,7-8,11H2,1H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007587 (CHEMBL3238288) Show SMILES C[C@](O)(COc1ccc(F)cc1C#N)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C20H16FN3O3/c1-20(26,12-27-18-6-5-15(21)9-14(18)11-23)19(25)24-8-7-16-13(10-22)3-2-4-17(16)24/h2-6,9,26H,7-8,12H2,1H3/t20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.10	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007597 (CHEMBL3233071) Show SMILES C[C@](O)(COc1ccc(Cl)cc1Cl)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C19H16Cl2N2O3/c1-19(25,11-26-17-6-5-13(20)9-15(17)21)18(24)23-8-7-14-12(10-22)3-2-4-16(14)23/h2-6,9,25H,7-8,11H2,1H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.10	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007602 (CHEMBL3238276) Show SMILES C[C@](O)(COc1ccccc1F)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C19H17FN2O3/c1-19(24,12-25-17-8-3-2-6-15(17)20)18(23)22-10-9-14-13(11-21)5-4-7-16(14)22/h2-8,24H,9-10,12H2,1H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007589 (CHEMBL3238290) Show SMILES Cc1cc(F)ccc1OC[C@](C)(O)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C20H19FN2O3/c1-13-10-15(21)6-7-18(13)26-12-20(2,25)19(24)23-9-8-16-14(11-22)4-3-5-17(16)23/h3-7,10,25H,8-9,12H2,1-2H3/t20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007588 (CHEMBL3238289) Show SMILES C[C@](O)(COc1ccc(F)cc1Br)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C19H16BrFN2O3/c1-19(25,11-26-17-6-5-13(21)9-15(17)20)18(24)23-8-7-14-12(10-22)3-2-4-16(14)23/h2-6,9,25H,7-8,11H2,1H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007600 (CHEMBL3238274) Show SMILES C[C@](O)(COc1ccc(F)cc1)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C19H17FN2O3/c1-19(24,12-25-15-7-5-14(20)6-8-15)18(23)22-10-9-16-13(11-21)3-2-4-17(16)22/h2-8,24H,9-10,12H2,1H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007586 (CHEMBL3238287) Show SMILES C[C@](O)(COc1ccccc1C#N)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C20H17N3O3/c1-20(25,13-26-18-8-3-2-5-15(18)12-22)19(24)23-10-9-16-14(11-21)6-4-7-17(16)23/h2-8,25H,9-10,13H2,1H3/t20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM9504 (2-[(pyridin-4-ylmethyl)amino]-N-(quinolin-3-yl)ben...) Show SMILES O=C(Nc1cnc2ccccc2c1)c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C22H18N4O/c27-22(26-18-13-17-5-1-3-7-20(17)25-15-18)19-6-2-4-8-21(19)24-14-16-9-11-23-12-10-16/h1-13,15,24H,14H2,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	7.5	22
Chemical Diversity, Inc					Assay Description The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...				Bioorg Med Chem Lett 16: 602-6 (2006) Article DOI: 10.1016/j.bmcl.2005.10.058 BindingDB Entry DOI: 10.7270/Q2H1307W
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM9504 (2-[(pyridin-4-ylmethyl)amino]-N-(quinolin-3-yl)ben...) Show SMILES O=C(Nc1cnc2ccccc2c1)c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C22H18N4O/c27-22(26-18-13-17-5-1-3-7-20(17)25-15-18)19-6-2-4-8-21(19)24-14-16-9-11-23-12-10-16/h1-13,15,24H,14H2,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR2 by enzymatic assay				Bioorg Med Chem Lett 16: 1440-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.033 BindingDB Entry DOI: 10.7270/Q2NP240T
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM9504 (2-[(pyridin-4-ylmethyl)amino]-N-(quinolin-3-yl)ben...) Show SMILES O=C(Nc1cnc2ccccc2c1)c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C22H18N4O/c27-22(26-18-13-17-5-1-3-7-20(17)25-15-18)19-6-2-4-8-21(19)24-14-16-9-11-23-12-10-16/h1-13,15,24H,14H2,(H,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR1 by HTRF assay				Bioorg Med Chem Lett 17: 1369-75 (2007) Article DOI: 10.1016/j.bmcl.2006.11.087 BindingDB Entry DOI: 10.7270/Q2125S92
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM84749 (N-(3-methylphenyl)-2-(pyridin-4-ylmethylamino)benz...) Show SMILES Cc1cccc(NC(=O)c2ccccc2NCc2ccncc2)c1 Show InChI InChI=1S/C20H19N3O/c1-15-5-4-6-17(13-15)23-20(24)18-7-2-3-8-19(18)22-14-16-9-11-21-12-10-16/h2-13,22H,14H2,1H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	7.5	25
ChemDiv Inc.					Assay Description In a representative synthetic procedure (compound 3), a mixture of 1 (330 mg, 2 mM) and 3-F3C-C6H4-NHNH2 (370 mg, 2.1 mM) in anisole (20 mL) was stir...				Chem Biol Drug Des 69: 331-7 (2007) Article DOI: 10.1111/j.1747-0285.2007.00507.x BindingDB Entry DOI: 10.7270/Q2DR2T12
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM9504 (2-[(pyridin-4-ylmethyl)amino]-N-(quinolin-3-yl)ben...) Show SMILES O=C(Nc1cnc2ccccc2c1)c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C22H18N4O/c27-22(26-18-13-17-5-1-3-7-20(17)25-15-18)19-6-2-4-8-21(19)24-14-16-9-11-23-12-10-16/h1-13,15,24H,14H2,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Inc. Curated by ChEMBL					Assay Description Inhibitory activity against VEGFR-2 using 2 uM ATP by HTRF assay				Bioorg Med Chem Lett 16: 1726-30 (2006) Article DOI: 10.1016/j.bmcl.2005.11.105 BindingDB Entry DOI: 10.7270/Q2HQ3ZF2
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007592 (CHEMBL3238293) Show SMILES COc1cc(ccc1OC[C@](C)(O)C(=O)N1CCc2c1cccc2C#N)C#N |r| Show InChI InChI=1S/C21H19N3O4/c1-21(26,13-28-18-7-6-14(11-22)10-19(18)27-2)20(25)24-9-8-16-15(12-23)4-3-5-17(16)24/h3-7,10,26H,8-9,13H2,1-2H3/t21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007584 (CHEMBL3238285) Show SMILES C[C@](O)(COc1ccc(cc1)C#N)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C20H17N3O3/c1-20(25,13-26-16-7-5-14(11-21)6-8-16)19(24)23-10-9-17-15(12-22)3-2-4-18(17)23/h2-8,25H,9-10,13H2,1H3/t20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50179883 ((4-Isopropylphenyl)-(4-isoquinolin-5-yl-phthalazin...) Show SMILES CC(C)c1ccc(Nc2nnc(-c3cccc4cnccc34)c3ccccc23)cc1 Show InChI InChI=1S/C26H22N4/c1-17(2)18-10-12-20(13-11-18)28-26-24-8-4-3-7-23(24)25(29-30-26)22-9-5-6-19-16-27-15-14-21(19)22/h3-17H,1-2H3,(H,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Curated by ChEMBL					Assay Description Inhibition of VEGFR2 by HTRF assay				Bioorg Med Chem Lett 16: 1579-81 (2006) Article DOI: 10.1016/j.bmcl.2005.12.045 BindingDB Entry DOI: 10.7270/Q2WS8SVC
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50179883 ((4-Isopropylphenyl)-(4-isoquinolin-5-yl-phthalazin...) Show SMILES CC(C)c1ccc(Nc2nnc(-c3cccc4cnccc34)c3ccccc23)cc1 Show InChI InChI=1S/C26H22N4/c1-17(2)18-10-12-20(13-11-18)28-26-24-8-4-3-7-23(24)25(29-30-26)22-9-5-6-19-16-27-15-14-21(19)22/h3-17H,1-2H3,(H,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF method				Bioorg Med Chem 17: 731-40 (2009) Article DOI: 10.1016/j.bmc.2008.11.049 BindingDB Entry DOI: 10.7270/Q2W95929
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM4851 ((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...) Show SMILES Clc1ccc(Nc2nnc(Cc3ccncc3)c3ccccc23)cc1 Show InChI InChI=1S/C20H15ClN4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14/h1-12H,13H2,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR2 in 293 adenovirus transfected kidney cells by cell-based ELISA assay				Bioorg Med Chem Lett 16: 1440-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.033 BindingDB Entry DOI: 10.7270/Q2NP240T
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM4851 ((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...) Show SMILES Clc1ccc(Nc2nnc(Cc3ccncc3)c3ccccc23)cc1 Show InChI InChI=1S/C20H15ClN4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14/h1-12H,13H2,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR2 by cell-based assay				Bioorg Med Chem Lett 17: 1369-75 (2007) Article DOI: 10.1016/j.bmcl.2006.11.087 BindingDB Entry DOI: 10.7270/Q2125S92
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM21 (CHEMBL24828 | N-(4-bromo-2-fluorophenyl)-6-methoxy...) Show SMILES COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC1CCN(C)CC1 Show InChI InChI=1S/C22H24BrFN4O2/c1-28-7-5-14(6-8-28)12-30-21-11-19-16(10-20(21)29-2)22(26-13-25-19)27-18-4-3-15(23)9-17(18)24/h3-4,9-11,13-14H,5-8,12H2,1-2H3,(H,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR2 by enzymatic assay				Bioorg Med Chem Lett 16: 1440-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.033 BindingDB Entry DOI: 10.7270/Q2NP240T
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM21 (CHEMBL24828 | N-(4-bromo-2-fluorophenyl)-6-methoxy...) Show SMILES COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC1CCN(C)CC1 Show InChI InChI=1S/C22H24BrFN4O2/c1-28-7-5-14(6-8-28)12-30-21-11-19-16(10-20(21)29-2)22(26-13-25-19)27-18-4-3-15(23)9-17(18)24/h3-4,9-11,13-14H,5-8,12H2,1-2H3,(H,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	7.5	22
Chemical Diversity, Inc					Assay Description The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...				Bioorg Med Chem Lett 16: 602-6 (2006) Article DOI: 10.1016/j.bmcl.2005.10.058 BindingDB Entry DOI: 10.7270/Q2H1307W
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM21 (CHEMBL24828 | N-(4-bromo-2-fluorophenyl)-6-methoxy...) Show SMILES COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC1CCN(C)CC1 Show InChI InChI=1S/C22H24BrFN4O2/c1-28-7-5-14(6-8-28)12-30-21-11-19-16(10-20(21)29-2)22(26-13-25-19)27-18-4-3-15(23)9-17(18)24/h3-4,9-11,13-14H,5-8,12H2,1-2H3,(H,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Inc. Curated by ChEMBL					Assay Description Inhibitory activity against VEGFR-2 using 2 uM ATP by HTRF assay				Bioorg Med Chem Lett 16: 1726-30 (2006) Article DOI: 10.1016/j.bmcl.2005.11.105 BindingDB Entry DOI: 10.7270/Q2HQ3ZF2
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM21 (CHEMBL24828 | N-(4-bromo-2-fluorophenyl)-6-methoxy...) Show SMILES COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC1CCN(C)CC1 Show InChI InChI=1S/C22H24BrFN4O2/c1-28-7-5-14(6-8-28)12-30-21-11-19-16(10-20(21)29-2)22(26-13-25-19)27-18-4-3-15(23)9-17(18)24/h3-4,9-11,13-14H,5-8,12H2,1-2H3,(H,25,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR1 by HTRF assay				Bioorg Med Chem Lett 17: 1369-75 (2007) Article DOI: 10.1016/j.bmcl.2006.11.087 BindingDB Entry DOI: 10.7270/Q2125S92
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM84747 ((B) ZD6474 | US10155768, Vandetanib | US10183928, ...) Show SMILES CN1CCC(COc2cc3ncnc(Nc4ccc(Br)cc4F)c3cc2C)CC1 Show InChI InChI=1S/C23H25BrFN3O/c1-15-9-19-21(10-17-3-4-18(24)11-20(17)25)26-14-27-22(19)12-23(15)29-13-16-5-7-28(2)8-6-16/h3-4,9,11-12,14,16H,5-8,10,13H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	25
ChemDiv Inc.					Assay Description In a representative synthetic procedure (compound 3), a mixture of 1 (330 mg, 2 mM) and 3-F3C-C6H4-NHNH2 (370 mg, 2.1 mM) in anisole (20 mL) was stir...				Chem Biol Drug Des 69: 331-7 (2007) Article DOI: 10.1111/j.1747-0285.2007.00507.x BindingDB Entry DOI: 10.7270/Q2DR2T12
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM9503 (2-[(pyridin-4-ylmethyl)amino]-N-[3-(trifluoromethy...) Show SMILES FC(F)(F)c1cccc(NC(=O)c2ccccc2NCc2ccncc2)c1 Show InChI InChI=1S/C20H16F3N3O/c21-20(22,23)15-4-3-5-16(12-15)26-19(27)17-6-1-2-7-18(17)25-13-14-8-10-24-11-9-14/h1-12,25H,13H2,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Inc. Curated by ChEMBL					Assay Description Inhibitory activity against VEGFR-2 using 2 uM ATP by HTRF assay				Bioorg Med Chem Lett 16: 1726-30 (2006) Article DOI: 10.1016/j.bmcl.2005.11.105 BindingDB Entry DOI: 10.7270/Q2HQ3ZF2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM9504 (2-[(pyridin-4-ylmethyl)amino]-N-(quinolin-3-yl)ben...) Show SMILES O=C(Nc1cnc2ccccc2c1)c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C22H18N4O/c27-22(26-18-13-17-5-1-3-7-20(17)25-15-18)19-6-2-4-8-21(19)24-14-16-9-11-23-12-10-16/h1-13,15,24H,14H2,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	25
ChemDiv Inc.					Assay Description In a representative synthetic procedure (compound 3), a mixture of 1 (330 mg, 2 mM) and 3-F3C-C6H4-NHNH2 (370 mg, 2.1 mM) in anisole (20 mL) was stir...				Chem Biol Drug Des 69: 331-7 (2007) Article DOI: 10.1111/j.1747-0285.2007.00507.x BindingDB Entry DOI: 10.7270/Q2DR2T12
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM9503 (2-[(pyridin-4-ylmethyl)amino]-N-[3-(trifluoromethy...) Show SMILES FC(F)(F)c1cccc(NC(=O)c2ccccc2NCc2ccncc2)c1 Show InChI InChI=1S/C20H16F3N3O/c21-20(22,23)15-4-3-5-16(12-15)26-19(27)17-6-1-2-7-18(17)25-13-14-8-10-24-11-9-14/h1-12,25H,13H2,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	7.5	22
Chemical Diversity, Inc					Assay Description The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...				Bioorg Med Chem Lett 16: 602-6 (2006) Article DOI: 10.1016/j.bmcl.2005.10.058 BindingDB Entry DOI: 10.7270/Q2H1307W
					More data for this Ligand-Target Pair				3D Structure (crystal)
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM9503 (2-[(pyridin-4-ylmethyl)amino]-N-[3-(trifluoromethy...) Show SMILES FC(F)(F)c1cccc(NC(=O)c2ccccc2NCc2ccncc2)c1 Show InChI InChI=1S/C20H16F3N3O/c21-20(22,23)15-4-3-5-16(12-15)26-19(27)17-6-1-2-7-18(17)25-13-14-8-10-24-11-9-14/h1-12,25H,13H2,(H,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR1 by HTRF assay				Bioorg Med Chem Lett 17: 1369-75 (2007) Article DOI: 10.1016/j.bmcl.2006.11.087 BindingDB Entry DOI: 10.7270/Q2125S92
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM9503 (2-[(pyridin-4-ylmethyl)amino]-N-[3-(trifluoromethy...) Show SMILES FC(F)(F)c1cccc(NC(=O)c2ccccc2NCc2ccncc2)c1 Show InChI InChI=1S/C20H16F3N3O/c21-20(22,23)15-4-3-5-16(12-15)26-19(27)17-6-1-2-7-18(17)25-13-14-8-10-24-11-9-14/h1-12,25H,13H2,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR2 by enzymatic assay				Bioorg Med Chem Lett 16: 1440-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.033 BindingDB Entry DOI: 10.7270/Q2NP240T
					More data for this Ligand-Target Pair				3D Structure (crystal)
Androgen receptor (Homo sapiens (Human))	BDBM50007607 (CHEMBL3238281) Show SMILES C[C@](O)(COc1ccc(cc1)C(F)(F)F)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C20H17F3N2O3/c1-19(27,12-28-15-7-5-14(6-8-15)20(21,22)23)18(26)25-10-9-16-13(11-24)3-2-4-17(16)25/h2-8,27H,9-10,12H2,1H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007601 (CHEMBL3238275) Show SMILES C[C@](O)(COc1cccc(F)c1)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C19H17FN2O3/c1-19(24,12-25-15-6-3-5-14(20)10-15)18(23)22-9-8-16-13(11-21)4-2-7-17(16)22/h2-7,10,24H,8-9,12H2,1H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007603 (CHEMBL3238277) Show SMILES C[C@](O)(COc1ccc(Cl)cc1)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C19H17ClN2O3/c1-19(24,12-25-15-7-5-14(20)6-8-15)18(23)22-10-9-16-13(11-21)3-2-4-17(16)22/h2-8,24H,9-10,12H2,1H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50007598 (CHEMBL3233072) Show SMILES C[C@](O)(COc1ccc(Br)cc1F)C(=O)N1CCc2c1cccc2C#N |r| Show InChI InChI=1S/C19H16BrFN2O3/c1-19(25,11-26-17-6-5-13(20)9-15(17)21)18(24)23-8-7-14-12(10-22)3-2-4-16(14)23/h2-6,9,25H,7-8,11H2,1H3/t19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]mibolerone from full length human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting				J Med Chem 57: 2462-71 (2014) Article DOI: 10.1021/jm401625b BindingDB Entry DOI: 10.7270/Q2RB763C
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50178528 (CHEMBL205127 | N-(4-chloro-3-(trifluoromethyl)phen...) Show SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(Nc2ccc(Cl)c(c2)C(F)(F)F)o1 Show InChI InChI=1S/C19H15ClF3N7O/c1-30-10-26-16(25-9-11-4-6-24-7-5-11)15(30)17-28-29-18(31-17)27-12-2-3-14(20)13(8-12)19(21,22)23/h2-8,10,25H,9H2,1H3,(H,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR2 by enzymatic assay				Bioorg Med Chem Lett 16: 1440-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.033 BindingDB Entry DOI: 10.7270/Q2NP240T
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM21 (CHEMBL24828 | N-(4-bromo-2-fluorophenyl)-6-methoxy...) Show SMILES COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC1CCN(C)CC1 Show InChI InChI=1S/C22H24BrFN4O2/c1-28-7-5-14(6-8-28)12-30-21-11-19-16(10-20(21)29-2)22(26-13-25-19)27-18-4-3-15(23)9-17(18)24/h3-4,9-11,13-14H,5-8,12H2,1-2H3,(H,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF method				Bioorg Med Chem 17: 731-40 (2009) Article DOI: 10.1016/j.bmc.2008.11.049 BindingDB Entry DOI: 10.7270/Q2W95929
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50201357 (CHEMBL401041 | N-(4-tert-butylphenyl)-1-methyl-4-(...) Show SMILES Cn1ncc(NCc2ccncc2)c1C(=O)Nc1ccc(cc1)C(C)(C)C Show InChI InChI=1S/C21H25N5O/c1-21(2,3)16-5-7-17(8-6-16)25-20(27)19-18(14-24-26(19)4)23-13-15-9-11-22-12-10-15/h5-12,14,23H,13H2,1-4H3,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR2 by cell-based assay				Bioorg Med Chem Lett 17: 1369-75 (2007) Article DOI: 10.1016/j.bmcl.2006.11.087 BindingDB Entry DOI: 10.7270/Q2125S92
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50178509 (5-(1-methyl-4-(pyridin-4-ylmethylamino)-1H-imidazo...) Show SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(Nc2cccc(OC(F)(F)F)c2)o1 Show InChI InChI=1S/C19H16F3N7O2/c1-29-11-25-16(24-10-12-5-7-23-8-6-12)15(29)17-27-28-18(30-17)26-13-3-2-4-14(9-13)31-19(20,21)22/h2-9,11,24H,10H2,1H3,(H,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR2 by enzymatic assay				Bioorg Med Chem Lett 16: 1440-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.033 BindingDB Entry DOI: 10.7270/Q2NP240T
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM84761 ((15) 1H-1,2,4-triazol-3-yl-anilines 3-Br-(C6H4) 4-...) Show SMILES Brc1cccc(c1)-n1cnc(n1)-c1ccccc1Nc1ccncc1 Show InChI InChI=1S/C19H14BrN5/c20-14-4-3-5-16(12-14)25-13-22-19(24-25)17-6-1-2-7-18(17)23-15-8-10-21-11-9-15/h1-13H,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	7.5	25
ChemDiv Inc.					Assay Description In a representative synthetic procedure (compound 3), a mixture of 1 (330 mg, 2 mM) and 3-F3C-C6H4-NHNH2 (370 mg, 2.1 mM) in anisole (20 mL) was stir...				Chem Biol Drug Des 69: 331-7 (2007) Article DOI: 10.1111/j.1747-0285.2007.00507.x BindingDB Entry DOI: 10.7270/Q2DR2T12
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50179152 (2-((5H-imidazo[4,5-c]pyridin-5-yl)methyl)-N-(4-chl...) Show SMILES Clc1ccc(NC(=O)c2ccccc2Cn2ccc3ncnc3c2)cc1 Show InChI InChI=1S/C20H15ClN4O/c21-15-5-7-16(8-6-15)24-20(26)17-4-2-1-3-14(17)11-25-10-9-18-19(12-25)23-13-22-18/h1-10,12-13H,11H2,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity Inc. Curated by ChEMBL					Assay Description Inhibitory activity against VEGFR-2 using 2 uM ATP by HTRF assay				Bioorg Med Chem Lett 16: 1726-30 (2006) Article DOI: 10.1016/j.bmcl.2005.11.105 BindingDB Entry DOI: 10.7270/Q2HQ3ZF2
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM84755 ((9) 1H-1,2,4-triazol-3-yl-anilines 3-F3CO(C6H4) 4-...) Show SMILES FC(F)(F)Oc1cccc(c1)-n1cnc(n1)-c1ccccc1Nc1ccncc1 Show InChI InChI=1S/C20H14F3N5O/c21-20(22,23)29-16-5-3-4-15(12-16)28-13-25-19(27-28)17-6-1-2-7-18(17)26-14-8-10-24-11-9-14/h1-13H,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	7.5	25
ChemDiv Inc.					Assay Description In a representative synthetic procedure (compound 3), a mixture of 1 (330 mg, 2 mM) and 3-F3C-C6H4-NHNH2 (370 mg, 2.1 mM) in anisole (20 mL) was stir...				Chem Biol Drug Des 69: 331-7 (2007) Article DOI: 10.1111/j.1747-0285.2007.00507.x BindingDB Entry DOI: 10.7270/Q2DR2T12
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50179881 ((4-Chlorophenyl)-(4-isoquinolin-5-yl-phthalazin-1-...) Show SMILES Clc1ccc(Nc2nnc(-c3cccc4cnccc34)c3ccccc23)cc1 Show InChI InChI=1S/C23H15ClN4/c24-16-8-10-17(11-9-16)26-23-21-6-2-1-5-20(21)22(27-28-23)19-7-3-4-15-14-25-13-12-18(15)19/h1-14H,(H,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) by HTRF method				Bioorg Med Chem 17: 731-40 (2009) Article DOI: 10.1016/j.bmc.2008.11.049 BindingDB Entry DOI: 10.7270/Q2W95929
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50179881 ((4-Chlorophenyl)-(4-isoquinolin-5-yl-phthalazin-1-...) Show SMILES Clc1ccc(Nc2nnc(-c3cccc4cnccc34)c3ccccc23)cc1 Show InChI InChI=1S/C23H15ClN4/c24-16-8-10-17(11-9-16)26-23-21-6-2-1-5-20(21)22(27-28-23)19-7-3-4-15-14-25-13-12-18(15)19/h1-14H,(H,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
ImClone Systems Curated by ChEMBL					Assay Description Inhibition of VEGFR2 by HTRF assay				Bioorg Med Chem Lett 16: 1579-81 (2006) Article DOI: 10.1016/j.bmcl.2005.12.045 BindingDB Entry DOI: 10.7270/Q2WS8SVC
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM9504 (2-[(pyridin-4-ylmethyl)amino]-N-(quinolin-3-yl)ben...) Show SMILES O=C(Nc1cnc2ccccc2c1)c1ccccc1NCc1ccncc1 Show InChI InChI=1S/C22H18N4O/c27-22(26-18-13-17-5-1-3-7-20(17)25-15-18)19-6-2-4-8-21(19)24-14-16-9-11-23-12-10-16/h1-13,15,24H,14H2,(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Chemical Diversity, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR2 in 293 adenovirus transfected kidney cells by cell-based ELISA assay				Bioorg Med Chem Lett 16: 1440-4 (2006) Article DOI: 10.1016/j.bmcl.2005.11.033 BindingDB Entry DOI: 10.7270/Q2NP240T
					More data for this Ligand-Target Pair

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