Compile Data Set for Download or QSAR

Found 184 hits with Last Name = 'pridal' and Initial = 'l'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50146832 (1-(3,4-Dimethoxy-phenyl)-4-[4-(1-ethyl-propyl)-pip...) Show SMILES CCC(CC)N1CCN(CC1)C(=O)CCC(=O)c1ccc(OC)c(OC)c1 Show InChI InChI=1S/C21H32N2O4/c1-5-17(6-2)22-11-13-23(14-12-22)21(25)10-8-18(24)16-7-9-19(26-3)20(15-16)27-4/h7,9,15,17H,5-6,8,10-14H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50370330 (CHEMBL1202893) Show SMILES CCC(CC)N1CCN(CC1)C(=O)CCC(=O)c1ccc(OC)c(F)c1 Show InChI InChI=1S/C20H29FN2O3/c1-4-16(5-2)22-10-12-23(13-11-22)20(25)9-7-18(24)15-6-8-19(26-3)17(21)14-15/h6,8,14,16H,4-5,7,9-13H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50146836 (1-(4-Chloro-phenyl)-4-[4-(1,1-dimethyl-propyl)-pip...) Show SMILES CCC(C)(C)N1CCN(CC1)C(=O)CCC(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C19H27ClN2O2/c1-4-19(2,3)22-13-11-21(12-14-22)18(24)10-9-17(23)15-5-7-16(20)8-6-15/h5-8H,4,9-14H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.540	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM22541 (Clobenpropit | N''-[(4-chlorophenyl)methyl]{[3-(1H...) Show SMILES NC(SCCCc1cnc[nH]1)=NCc1ccc(Cl)cc1 |w:11.12| Show InChI InChI=1S/C14H17ClN4S/c15-12-5-3-11(4-6-12)8-18-14(16)20-7-1-2-13-9-17-10-19-13/h3-6,9-10H,1-2,7-8H2,(H2,16,18)(H,17,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	0.580	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50370328 (CHEMBL1202892) Show SMILES CCC(CC)N1CCN(CC1)C(=O)CCOc1ccc(cc1)C#N Show InChI InChI=1S/C19H27N3O2/c1-3-17(4-2)21-10-12-22(13-11-21)19(23)9-14-24-18-7-5-16(15-20)6-8-18/h5-8,17H,3-4,9-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.740	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50146838 (1-(4-Chloro-phenyl)-4-[4-(1-ethyl-propyl)-piperazi...) Show SMILES CCC(CC)N1CCN(CC1)C(=O)CCC(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C19H27ClN2O2/c1-3-17(4-2)21-11-13-22(14-12-21)19(24)10-9-18(23)15-5-7-16(20)8-6-15/h5-8,17H,3-4,9-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.860	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50370331 (CHEMBL1202896) Show SMILES CCC(CC)N1CCN(CC1)C(=O)Cc1ccc(cc1)N(C)C Show InChI InChI=1S/C19H31N3O/c1-5-17(6-2)21-11-13-22(14-12-21)19(23)15-16-7-9-18(10-8-16)20(3)4/h7-10,17H,5-6,11-15H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.960	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50146840 (3-(4-Chloro-phenoxy)-1-[4-(1-ethyl-propyl)-piperaz...) Show SMILES CCC(CC)N1CCN(CC1)C(=O)CCOc1ccc(Cl)cc1 Show InChI InChI=1S/C18H27ClN2O2/c1-3-16(4-2)20-10-12-21(13-11-20)18(22)9-14-23-17-7-5-15(19)6-8-17/h5-8,16H,3-4,9-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50146835 (1-(4-Chloro-phenyl)-4-(4-cyclopentyl-piperazin-1-y...) Show SMILES Clc1ccc(cc1)C(=O)CCC(=O)N1CCN(CC1)C1CCCC1 Show InChI InChI=1S/C19H25ClN2O2/c20-16-7-5-15(6-8-16)18(23)9-10-19(24)22-13-11-21(12-14-22)17-3-1-2-4-17/h5-8,17H,1-4,9-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50146826 (1-(4-Chloro-phenyl)-4-(4-cyclobutyl-piperazin-1-yl...) Show SMILES Clc1ccc(cc1)C(=O)CCC(=O)N1CCN(CC1)C1CCC1 Show InChI InChI=1S/C18H23ClN2O2/c19-15-6-4-14(5-7-15)17(22)8-9-18(23)21-12-10-20(11-13-21)16-2-1-3-16/h4-7,16H,1-3,8-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50370336 (CHEMBL1202903) Show SMILES CCC(CC)N1CCN(CC1)C(=O)CCC(=O)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C20H27F3N2O2/c1-3-17(4-2)24-11-13-25(14-12-24)19(27)10-9-18(26)15-5-7-16(8-6-15)20(21,22)23/h5-8,17H,3-4,9-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50370338 (CHEMBL1202904) Show SMILES CCC(CC)N1CCN(CC1)C(=O)CCC(=O)c1ccc(F)cc1 Show InChI InChI=1S/C19H27FN2O2/c1-3-17(4-2)21-11-13-22(14-12-21)19(24)10-9-18(23)15-5-7-16(20)8-6-15/h5-8,17H,3-4,9-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50370327 (CHEMBL1202901) Show SMILES CCC(CC)N1CCN(CC1)C(=O)Cc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C18H25F3N2O/c1-3-16(4-2)22-9-11-23(12-10-22)17(24)13-14-5-7-15(8-6-14)18(19,20)21/h5-8,16H,3-4,9-13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50370326 (CHEMBL1202900) Show SMILES CCC(CC)N1CCN(CC1)C(=O)Cc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C18H25F3N2O2/c1-3-15(4-2)22-9-11-23(12-10-22)17(24)13-14-5-7-16(8-6-14)25-18(19,20)21/h5-8,15H,3-4,9-13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50370329 (CHEMBL1202894) Show SMILES CCC(CC)N1CCN(CC1)C(=O)CCC(=O)c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C20H27F3N2O3/c1-3-16(4-2)24-11-13-25(14-12-24)19(27)10-9-18(26)15-5-7-17(8-6-15)28-20(21,22)23/h5-8,16H,3-4,9-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM22904 ((2R)-1-(1H-imidazol-5-yl)propan-2-amine | (R)-alph...) Show SMILES C[C@@H](N)Cc1cnc[nH]1 |r| Show InChI InChI=1S/C6H11N3/c1-5(7)2-6-3-8-4-9-6/h3-5H,2,7H2,1H3,(H,8,9)/t5-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50370339 (CHEMBL1202899) Show SMILES CCC(CC)N1CCN(CC1)C(=O)Cc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C23H30N2O/c1-3-22(4-2)24-14-16-25(17-15-24)23(26)18-19-10-12-21(13-11-19)20-8-6-5-7-9-20/h5-13,22H,3-4,14-18H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50146843 (1-(4-Chloro-phenyl)-4-(4-cyclohexyl-piperazin-1-yl...) Show SMILES Clc1ccc(cc1)C(=O)CCC(=O)N1CCN(CC1)C1CCCCC1 Show InChI InChI=1S/C20H27ClN2O2/c21-17-8-6-16(7-9-17)19(24)10-11-20(25)23-14-12-22(13-15-23)18-4-2-1-3-5-18/h6-9,18H,1-5,10-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50146839 (1-(4-Chloro-phenyl)-4-(4-isopropyl-piperazin-1-yl)...) Show SMILES CC(C)N1CCN(CC1)C(=O)CCC(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C17H23ClN2O2/c1-13(2)19-9-11-20(12-10-19)17(22)8-7-16(21)14-3-5-15(18)6-4-14/h3-6,13H,7-12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50146820 (1-(4-Chloro-phenyl)-4-(4-cyclopropylmethyl-piperaz...) Show SMILES Clc1ccc(cc1)C(=O)CCC(=O)N1CCN(CC2CC2)CC1 Show InChI InChI=1S/C18H23ClN2O2/c19-16-5-3-15(4-6-16)17(22)7-8-18(23)21-11-9-20(10-12-21)13-14-1-2-14/h3-6,14H,1-2,7-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	8.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50370337 (CHEMBL1202902) Show SMILES CCC(CC)N1CCN(CC1)C(=O)CCc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C19H27F3N2O/c1-3-17(4-2)23-11-13-24(14-12-23)18(25)10-7-15-5-8-16(9-6-15)19(20,21)22/h5-6,8-9,17H,3-4,7,10-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50146818 (1-(4-Chloro-phenyl)-4-[4-(tetrahydro-pyran-4-yl)-p...) Show SMILES Clc1ccc(cc1)C(=O)CCC(=O)N1CCN(CC1)C1CCOCC1 Show InChI InChI=1S/C19H25ClN2O3/c20-16-3-1-15(2-4-16)18(23)5-6-19(24)22-11-9-21(10-12-22)17-7-13-25-14-8-17/h1-4,17H,5-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	9.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50146829 (1-(4-Chloro-phenyl)-4-(4-cyclopropyl-piperazin-1-y...) Show SMILES Clc1ccc(cc1)C(=O)CCC(=O)N1CCN(CC1)C1CC1 Show InChI InChI=1S/C17H21ClN2O2/c18-14-3-1-13(2-4-14)16(21)7-8-17(22)20-11-9-19(10-12-20)15-5-6-15/h1-4,15H,5-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	13.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM22914 (CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...) Show SMILES S=C(NC1CCCCC1)N1CCC(CC1)c1cnc[nH]1 Show InChI InChI=1S/C15H24N4S/c20-15(18-13-4-2-1-3-5-13)19-8-6-12(7-9-19)14-10-16-11-17-14/h10-13H,1-9H2,(H,16,17)(H,18,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50370334 (CHEMBL1202897) Show SMILES CCC(CC)N1CCN(CC1)C(=O)Cc1ccc(cc1)C(C)=O Show InChI InChI=1S/C19H28N2O2/c1-4-18(5-2)20-10-12-21(13-11-20)19(23)14-16-6-8-17(9-7-16)15(3)22/h6-9,18H,4-5,10-14H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50146842 (1-(4-Chloro-phenyl)-4-(4-cycloheptyl-piperazin-1-y...) Show SMILES Clc1ccc(cc1)C(=O)CCC(=O)N1CCN(CC1)C1CCCCCC1 Show InChI InChI=1S/C21H29ClN2O2/c22-18-9-7-17(8-10-18)20(25)11-12-21(26)24-15-13-23(14-16-24)19-5-3-1-2-4-6-19/h7-10,19H,1-6,11-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50146837 (1-(4-Chloro-phenyl)-4-[4-(1,1-dimethyl-prop-2-ynyl...) Show SMILES CC(C)(C#C)N1CCN(CC1)C(=O)CCC(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C19H23ClN2O2/c1-4-19(2,3)22-13-11-21(12-14-22)18(24)10-9-17(23)15-5-7-16(20)8-6-15/h1,5-8H,9-14H2,2-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	89	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50370335 (CHEMBL1202895) Show SMILES CCC(CC)N1CCN(CC1)C(=O)c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C17H23F3N2O2/c1-3-14(4-2)21-9-11-22(12-10-21)16(23)13-5-7-15(8-6-13)24-17(18,19)20/h5-8,14H,3-4,9-12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	93	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM27213 (4-[3-(4-cyclopropanecarbonylphenoxy)propyl]-1H-imi...) Show SMILES O=C(C1CC1)c1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C16H18N2O2/c19-16(12-3-4-12)13-5-7-15(8-6-13)20-9-1-2-14-10-17-11-18-14/h5-8,10-12H,1-4,9H2,(H,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	94	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50370332 (CHEMBL1202898) Show SMILES CCC(CC)N1CCN(CC1)C(=O)COc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C18H25F3N2O3/c1-3-14(4-2)22-9-11-23(12-10-22)17(24)13-25-15-5-7-16(8-6-15)26-18(19,20)21/h5-8,14H,3-4,9-13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50146819 (1-(4-Chloro-phenyl)-4-(4-cyclooctyl-piperazin-1-yl...) Show SMILES Clc1ccc(cc1)C(=O)CCC(=O)N1CCN(CC1)C1CCCCCCC1 Show InChI InChI=1S/C22H31ClN2O2/c23-19-10-8-18(9-11-19)21(26)12-13-22(27)25-16-14-24(15-17-25)20-6-4-2-1-3-5-7-20/h8-11,20H,1-7,12-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50146841 (1-(4-Chloro-phenyl)-4-[4-(1-propyl-butyl)-piperazi...) Show SMILES CCCC(CCC)N1CCN(CC1)C(=O)CCC(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H31ClN2O2/c1-3-5-19(6-4-2)23-13-15-24(16-14-23)21(26)12-11-20(25)17-7-9-18(22)10-8-17/h7-10,19H,3-6,11-16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	480	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50146844 (1-[4-(2-Chloro-allyl)-piperazin-1-yl]-4-(4-chloro-...) Show SMILES ClC(=C)CN1CCN(CC1)C(=O)CCC(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C17H20Cl2N2O2/c1-13(18)12-20-8-10-21(11-9-20)17(23)7-6-16(22)14-2-4-15(19)5-3-14/h2-5H,1,6-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Antagonist potency against human histamine H3 receptor expressed in CHO cells was determined by GTPgamma-S-assay				J Med Chem 47: 2833-8 (2004) Article DOI: 10.1021/jm031028z BindingDB Entry DOI: 10.7270/Q2T154CW
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50118351 ((2-Chloro-7,7-dioxo-4,7-dihydro-1,7lambda*6*-dithi...) Show SMILES CC1(CCC1)NC1=Nc2cc(Cl)sc2S(=O)(=O)N1 |t:7| Show InChI InChI=1S/C10H12ClN3O2S2/c1-10(3-2-4-10)13-9-12-6-5-7(11)17-8(6)18(15,16)14-9/h5H,2-4H2,1H3,(H2,12,13,14)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at high...				J Med Chem 45: 4171-87 (2002) BindingDB Entry DOI: 10.7270/Q2SF2VGM
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50202031 (3-(4-((1-(4-cyclohexenylphenyl)-3-(3,5-dichlorophe...) Show SMILES OC(=O)CCNC(=O)c1ccc(CN(C(=O)Nc2cc(Cl)cc(Cl)c2)c2ccc(cc2)C2=CCCCC2)cc1 |t:33| Show InChI InChI=1S/C30H29Cl2N3O4/c31-24-16-25(32)18-26(17-24)34-30(39)35(27-12-10-22(11-13-27)21-4-2-1-3-5-21)19-20-6-8-23(9-7-20)29(38)33-15-14-28(36)37/h4,6-13,16-18H,1-3,5,14-15,19H2,(H,33,38)(H,34,39)(H,36,37)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Inhibition of human cloned glucagon receptor expressed in BHK cells				J Med Chem 50: 113-28 (2007) Article DOI: 10.1021/jm058026u BindingDB Entry DOI: 10.7270/Q26M36GK
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM29124 (aminothiazole, 21) Show SMILES OC(=O)CCNC(=O)c1ccc(CN(c2nc(cs2)-c2ccc(cc2)C(F)(F)F)c2ccc(SC(F)(F)F)cc2)cc1 Show InChI InChI=1S/C28H21F6N3O3S2/c29-27(30,31)20-7-5-18(6-8-20)23-16-41-26(36-23)37(21-9-11-22(12-10-21)42-28(32,33)34)15-17-1-3-19(4-2-17)25(40)35-14-13-24(38)39/h1-12,16H,13-15H2,(H,35,40)(H,38,39)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	7.5	22
Novo Nordisk A/S					Assay Description Wheat Germ Agglutinin derivatized SPA beads containing a scintillant (WGA beads) (Amersham) bound the membranes of BHK cells transfected with the hum...				J Med Chem 52: 2989-3000 (2009) Article DOI: 10.1021/jm8016249 BindingDB Entry DOI: 10.7270/Q21Z42RS
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50202047 (3-(4-((1-(4-tert-butylcyclohexyl)-3-(4-isopropylph...) Show SMILES CC(C)c1ccc(NC(=O)N(Cc2ccc(cc2)C(=O)NCCC(O)=O)[C@H]2CC[C@@H](CC2)C(C)(C)C)cc1 |r,wU:26.26,wD:29.33,(-2.98,-45.99,;-1.67,-46.79,;-1.71,-48.33,;-.32,-46.06,;-.27,-44.52,;1.08,-43.79,;2.39,-44.6,;3.74,-43.87,;3.79,-42.33,;5.14,-41.6,;2.48,-41.52,;1.12,-42.25,;-.19,-41.45,;-1.55,-42.18,;-2.86,-41.37,;-2.81,-39.82,;-1.45,-39.11,;-.14,-39.91,;-4.12,-39.01,;-4.07,-37.47,;-5.48,-39.74,;-6.79,-38.93,;-8.14,-39.66,;-9.45,-38.85,;-9.41,-37.32,;-10.81,-39.59,;2.52,-39.98,;1.21,-39.18,;1.26,-37.64,;2.62,-36.91,;3.93,-37.72,;3.88,-39.25,;2.67,-35.37,;4.21,-35.39,;1.13,-35.35,;2.72,-33.83,;2.35,-46.13,;1,-46.87,)| Show InChI InChI=1S/C31H43N3O4/c1-21(2)23-10-14-26(15-11-23)33-30(38)34(27-16-12-25(13-17-27)31(3,4)5)20-22-6-8-24(9-7-22)29(37)32-19-18-28(35)36/h6-11,14-15,21,25,27H,12-13,16-20H2,1-5H3,(H,32,37)(H,33,38)(H,35,36)/t25-,27-	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Inhibition of human cloned glucagon receptor expressed in BHK cells				J Med Chem 50: 113-28 (2007) Article DOI: 10.1021/jm058026u BindingDB Entry DOI: 10.7270/Q26M36GK
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM29106 (aminothiazole, 3) Show SMILES OC(=O)CCNC(=O)c1ccc(CN(c2nc(cs2)-c2ccc(OC(F)(F)F)cc2)c2ccc(cc2)C2=CCCCC2)cc1 |t:39| Show InChI InChI=1S/C33H30F3N3O4S/c34-33(35,36)43-28-16-12-25(13-17-28)29-21-44-32(38-29)39(27-14-10-24(11-15-27)23-4-2-1-3-5-23)20-22-6-8-26(9-7-22)31(42)37-19-18-30(40)41/h4,6-17,21H,1-3,5,18-20H2,(H,37,42)(H,40,41)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	7.5	22
Novo Nordisk A/S					Assay Description Wheat Germ Agglutinin derivatized SPA beads containing a scintillant (WGA beads) (Amersham) bound the membranes of BHK cells transfected with the hum...				J Med Chem 52: 2989-3000 (2009) Article DOI: 10.1021/jm8016249 BindingDB Entry DOI: 10.7270/Q21Z42RS
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50202056 (CHEMBL219244 | cis-3-{4-[1-(4-tert-butylcyclohexyl...) Show SMILES CC(C)(C)[C@@H]1CC[C@@H](CC1)N(Cc1ccc(cc1)C(=O)NCCC(O)=O)C(=O)Nc1ccc(OC(F)(F)F)cc1 |r,wD:4.3,7.10,(28.28,-6.28,;26.74,-6.26,;25.21,-6.25,;26.79,-4.72,;26.7,-7.8,;28,-8.62,;27.96,-10.15,;26.59,-10.88,;25.29,-10.08,;25.34,-8.53,;26.55,-12.42,;25.19,-13.15,;23.88,-12.34,;22.52,-13.07,;21.21,-12.26,;21.26,-10.72,;22.62,-10,;23.94,-10.8,;19.95,-9.91,;20,-8.37,;18.6,-10.64,;17.29,-9.83,;15.93,-10.56,;14.62,-9.75,;14.67,-8.21,;13.27,-10.48,;27.86,-13.23,;29.22,-12.49,;27.82,-14.77,;26.46,-15.5,;25.16,-14.68,;23.8,-15.41,;23.76,-16.96,;22.4,-17.69,;22.36,-19.23,;20.82,-19.2,;23.9,-19.26,;22.35,-20.77,;25.08,-17.76,;26.43,-17.03,)| Show InChI InChI=1S/C29H36F3N3O5/c1-28(2,3)21-8-12-23(13-9-21)35(27(39)34-22-10-14-24(15-11-22)40-29(30,31)32)18-19-4-6-20(7-5-19)26(38)33-17-16-25(36)37/h4-7,10-11,14-15,21,23H,8-9,12-13,16-18H2,1-3H3,(H,33,38)(H,34,39)(H,36,37)/t21-,23+	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Inhibition of human cloned glucagon receptor expressed in BHK cells				J Med Chem 50: 113-28 (2007) Article DOI: 10.1021/jm058026u BindingDB Entry DOI: 10.7270/Q26M36GK
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM29107 (aminothiazole, 4) Show SMILES OC(=O)CCNC(=O)c1ccc(CN(c2nc(cs2)-c2ccc(cc2)C(F)(F)F)c2ccc(cc2)C2=CCCCC2)cc1 |t:38| Show InChI InChI=1S/C33H30F3N3O3S/c34-33(35,36)27-14-10-25(11-15-27)29-21-43-32(38-29)39(28-16-12-24(13-17-28)23-4-2-1-3-5-23)20-22-6-8-26(9-7-22)31(42)37-19-18-30(40)41/h4,6-17,21H,1-3,5,18-20H2,(H,37,42)(H,40,41)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	7.5	22
Novo Nordisk A/S					Assay Description Wheat Germ Agglutinin derivatized SPA beads containing a scintillant (WGA beads) (Amersham) bound the membranes of BHK cells transfected with the hum...				J Med Chem 52: 2989-3000 (2009) Article DOI: 10.1021/jm8016249 BindingDB Entry DOI: 10.7270/Q21Z42RS
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM29109 (aminothiazole, 6) Show SMILES OC(=O)CCNC(=O)c1ccc(CN(c2nc(cs2)-c2ccc(OC(F)(F)F)cc2)c2ccc-3c(Cc4ccccc-34)c2)cc1 Show InChI InChI=1S/C34H26F3N3O4S/c35-34(36,37)44-27-12-9-22(10-13-27)30-20-45-33(39-30)40(19-21-5-7-23(8-6-21)32(43)38-16-15-31(41)42)26-11-14-29-25(18-26)17-24-3-1-2-4-28(24)29/h1-14,18,20H,15-17,19H2,(H,38,43)(H,41,42)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	7.5	22
Novo Nordisk A/S					Assay Description Wheat Germ Agglutinin derivatized SPA beads containing a scintillant (WGA beads) (Amersham) bound the membranes of BHK cells transfected with the hum...				J Med Chem 52: 2989-3000 (2009) Article DOI: 10.1021/jm8016249 BindingDB Entry DOI: 10.7270/Q21Z42RS
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50144009 (3-{4-[1-(4-tert-Butyl-cyclohexyl)-3-(4-trifluorome...) Show SMILES CC(C)(C)[C@H]1CC[C@@H](CC1)N(Cc1ccc(cc1)C(=O)NCCC(O)=O)C(=O)Nc1ccc(OC(F)(F)F)cc1 |wU:4.3,wD:7.10,(10.18,2.9,;9.39,1.56,;8.05,2.34,;8.62,.21,;10.74,.78,;12.08,1.53,;13.41,.77,;13.41,-.77,;12.07,-1.54,;10.74,-.77,;14.74,-1.54,;14.74,-3.07,;13.39,-3.86,;12.07,-3.1,;10.74,-3.86,;10.74,-5.4,;12.07,-6.17,;13.41,-5.4,;9.41,-6.19,;9.43,-7.72,;8.06,-5.42,;6.74,-6.2,;5.4,-5.44,;4.07,-6.23,;2.73,-5.47,;4.07,-7.77,;16.06,-.77,;16.06,.77,;17.39,-1.54,;18.71,-.77,;20.04,-1.53,;21.38,-.77,;21.36,.78,;22.71,1.56,;22.7,3.09,;21.17,3.11,;24.23,3.11,;22.71,4.62,;20.04,1.55,;18.71,.77,)| Show InChI InChI=1S/C29H36F3N3O5/c1-28(2,3)21-8-12-23(13-9-21)35(27(39)34-22-10-14-24(15-11-22)40-29(30,31)32)18-19-4-6-20(7-5-19)26(38)33-17-16-25(36)37/h4-7,10-11,14-15,21,23H,8-9,12-13,16-18H2,1-3H3,(H,33,38)(H,34,39)(H,36,37)/t21-,23-	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Inhibition of human cloned glucagon receptor expressed in BHK cells				J Med Chem 50: 113-28 (2007) Article DOI: 10.1021/jm058026u BindingDB Entry DOI: 10.7270/Q26M36GK
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50202041 (CHEMBL375167 | trans-3-{4-[3-(3,5-Bis(trifluoromet...) Show SMILES CC(C)(C)[C@H]1CC[C@@H](CC1)N(Cc1ccc(cc1)C(=O)NCCC(O)=O)C(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F |r,wU:4.3,wD:7.10,(30.95,-37.95,;30.96,-39.49,;32.5,-39.49,;29.42,-39.5,;30.95,-41.03,;32.28,-41.81,;32.28,-43.34,;30.94,-44.11,;29.61,-43.35,;29.62,-41.8,;30.95,-45.65,;29.61,-46.42,;28.28,-45.65,;26.94,-46.42,;25.61,-45.65,;25.61,-44.11,;26.94,-43.34,;28.27,-44.1,;24.28,-43.34,;24.28,-41.8,;22.94,-44.11,;21.61,-43.34,;20.27,-44.11,;18.94,-43.34,;18.94,-41.8,;17.61,-44.11,;32.28,-46.42,;32.28,-47.96,;33.61,-45.64,;34.95,-46.41,;36.27,-45.64,;37.6,-46.4,;37.61,-47.95,;36.28,-48.72,;34.94,-47.95,;36.28,-50.26,;36.27,-51.79,;37.82,-50.26,;34.74,-50.26,;38.93,-45.62,;40.26,-44.84,;39.71,-46.95,;38.15,-44.3,)| Show InChI InChI=1S/C30H35F6N3O4/c1-28(2,3)20-8-10-24(11-9-20)39(17-18-4-6-19(7-5-18)26(42)37-13-12-25(40)41)27(43)38-23-15-21(29(31,32)33)14-22(16-23)30(34,35)36/h4-7,14-16,20,24H,8-13,17H2,1-3H3,(H,37,42)(H,38,43)(H,40,41)/t20-,24-	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Inhibition of human cloned glucagon receptor expressed in BHK cells				J Med Chem 50: 113-28 (2007) Article DOI: 10.1021/jm058026u BindingDB Entry DOI: 10.7270/Q26M36GK
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50202051 (CHEMBL373824 | trans-3-(4-((1-(4-tert-butylcyclohe...) Show SMILES CC(C)(C)[C@H]1CC[C@@H](CC1)N(Cc1ccc(cc1)C(=O)NCCC(O)=O)C(=O)Nc1ccc(OC(F)(F)F)cc1C#N |r,wU:7.10,wD:4.3,(7.81,-36.16,;6.27,-36.14,;4.73,-36.12,;6.32,-34.6,;6.22,-37.68,;4.86,-38.41,;4.81,-39.95,;6.11,-40.75,;7.48,-40.02,;7.52,-38.49,;6.07,-42.29,;4.72,-43.02,;3.4,-42.22,;2.04,-42.95,;.73,-42.14,;.78,-40.59,;2.15,-39.88,;3.46,-40.68,;-.53,-39.78,;-.48,-38.24,;-1.88,-40.51,;-3.19,-39.7,;-4.55,-40.43,;-5.86,-39.62,;-5.81,-38.09,;-7.21,-40.36,;7.38,-43.1,;8.74,-42.37,;7.34,-44.64,;5.98,-45.37,;4.68,-44.56,;3.32,-45.29,;3.28,-46.83,;1.92,-47.56,;1.88,-49.1,;1.87,-50.64,;.34,-49.07,;3.42,-49.13,;4.6,-47.64,;5.95,-46.9,;7.26,-47.7,;8.57,-48.5,)| Show InChI InChI=1S/C30H35F3N4O5/c1-29(2,3)22-8-10-23(11-9-22)37(18-19-4-6-20(7-5-19)27(40)35-15-14-26(38)39)28(41)36-25-13-12-24(16-21(25)17-34)42-30(31,32)33/h4-7,12-13,16,22-23H,8-11,14-15,18H2,1-3H3,(H,35,40)(H,36,41)(H,38,39)/t22-,23-	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Inhibition of human cloned glucagon receptor expressed in BHK cells				J Med Chem 50: 113-28 (2007) Article DOI: 10.1021/jm058026u BindingDB Entry DOI: 10.7270/Q26M36GK
					More data for this Ligand-Target Pair
Glucagon receptor (Rattus norvegicus)	BDBM50144009 (3-{4-[1-(4-tert-Butyl-cyclohexyl)-3-(4-trifluorome...) Show SMILES CC(C)(C)[C@H]1CC[C@@H](CC1)N(Cc1ccc(cc1)C(=O)NCCC(O)=O)C(=O)Nc1ccc(OC(F)(F)F)cc1 |wU:4.3,wD:7.10,(10.18,2.9,;9.39,1.56,;8.05,2.34,;8.62,.21,;10.74,.78,;12.08,1.53,;13.41,.77,;13.41,-.77,;12.07,-1.54,;10.74,-.77,;14.74,-1.54,;14.74,-3.07,;13.39,-3.86,;12.07,-3.1,;10.74,-3.86,;10.74,-5.4,;12.07,-6.17,;13.41,-5.4,;9.41,-6.19,;9.43,-7.72,;8.06,-5.42,;6.74,-6.2,;5.4,-5.44,;4.07,-6.23,;2.73,-5.47,;4.07,-7.77,;16.06,-.77,;16.06,.77,;17.39,-1.54,;18.71,-.77,;20.04,-1.53,;21.38,-.77,;21.36,.78,;22.71,1.56,;22.7,3.09,;21.17,3.11,;24.23,3.11,;22.71,4.62,;20.04,1.55,;18.71,.77,)| Show InChI InChI=1S/C29H36F3N3O5/c1-28(2,3)21-8-12-23(13-9-21)35(27(39)34-22-10-14-24(15-11-22)40-29(30,31)32)18-19-4-6-20(7-5-19)26(38)33-17-16-25(36)37/h4-7,10-11,14-15,21,23H,8-9,12-13,16-18H2,1-3H3,(H,33,38)(H,34,39)(H,36,37)/t21-,23-	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Inhibition of rat glucagon receptor				J Med Chem 50: 113-28 (2007) Article DOI: 10.1021/jm058026u BindingDB Entry DOI: 10.7270/Q26M36GK
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50202029 (3-(4-((1-(4-isopropylcyclohexyl)-3-(4-(trifluorome...) Show SMILES CC(C)C1CCC(CC1)N(Cc1ccc(cc1)C(=O)NCCC(O)=O)C(=O)Nc1ccc(OC(F)(F)F)cc1 |(25.03,-34.49,;23.7,-35.26,;22.37,-34.49,;23.7,-36.8,;25.03,-37.58,;25.03,-39.11,;23.69,-39.88,;22.36,-39.12,;22.36,-37.57,;23.69,-41.42,;22.36,-42.19,;21.02,-41.42,;19.69,-42.19,;18.35,-41.42,;18.35,-39.88,;19.68,-39.11,;21.02,-39.87,;17.02,-39.11,;17.02,-37.57,;15.69,-39.88,;14.35,-39.11,;13.02,-39.88,;11.68,-39.11,;11.69,-37.57,;10.35,-39.88,;25.02,-42.18,;25.03,-43.72,;26.36,-41.41,;27.69,-42.18,;27.69,-43.72,;29.02,-44.49,;30.35,-43.72,;31.69,-44.48,;31.69,-46.02,;31.68,-47.56,;33.23,-46.03,;30.15,-46.02,;30.35,-42.17,;29.01,-41.41,)| Show InChI InChI=1S/C28H34F3N3O5/c1-18(2)20-7-11-23(12-8-20)34(27(38)33-22-9-13-24(14-10-22)39-28(29,30)31)17-19-3-5-21(6-4-19)26(37)32-16-15-25(35)36/h3-6,9-10,13-14,18,20,23H,7-8,11-12,15-17H2,1-2H3,(H,32,37)(H,33,38)(H,35,36)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Inhibition of human cloned glucagon receptor expressed in BHK cells				J Med Chem 50: 113-28 (2007) Article DOI: 10.1021/jm058026u BindingDB Entry DOI: 10.7270/Q26M36GK
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50202039 (3-(4-((1-(4-cyclohexylphenyl)-3-(4-(trifluorometho...) Show SMILES OC(=O)CCNC(=O)c1ccc(CN(C(=O)Nc2ccc(OC(F)(F)F)cc2)c2ccc(cc2)C2CCCCC2)cc1 Show InChI InChI=1S/C31H32F3N3O5/c32-31(33,34)42-27-16-12-25(13-17-27)36-30(41)37(26-14-10-23(11-15-26)22-4-2-1-3-5-22)20-21-6-8-24(9-7-21)29(40)35-19-18-28(38)39/h6-17,22H,1-5,18-20H2,(H,35,40)(H,36,41)(H,38,39)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Inhibition of human cloned glucagon receptor expressed in BHK cells				J Med Chem 50: 113-28 (2007) Article DOI: 10.1021/jm058026u BindingDB Entry DOI: 10.7270/Q26M36GK
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM29119 (aminothiazole, 16) Show SMILES OC(=O)CCNC(=O)c1ccc(CN(c2nc(cs2)-c2ccc(cc2)C(F)(F)F)c2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C27H21ClF3N3O3S/c28-21-9-11-22(12-10-21)34(15-17-1-3-19(4-2-17)25(37)32-14-13-24(35)36)26-33-23(16-38-26)18-5-7-20(8-6-18)27(29,30)31/h1-12,16H,13-15H2,(H,32,37)(H,35,36)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	7.5	22
Novo Nordisk A/S					Assay Description Wheat Germ Agglutinin derivatized SPA beads containing a scintillant (WGA beads) (Amersham) bound the membranes of BHK cells transfected with the hum...				J Med Chem 52: 2989-3000 (2009) Article DOI: 10.1021/jm8016249 BindingDB Entry DOI: 10.7270/Q21Z42RS
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM29114 (aminothiazole, 11) Show SMILES OC(=O)CCNC(=O)c1ccc(CN(c2nc(cs2)-c2ccc(cc2)C(F)(F)F)c2ccc3CCCCc3c2)cc1 Show InChI InChI=1S/C31H28F3N3O3S/c32-31(33,34)25-12-9-22(10-13-25)27-19-41-30(36-27)37(26-14-11-21-3-1-2-4-24(21)17-26)18-20-5-7-23(8-6-20)29(40)35-16-15-28(38)39/h5-14,17,19H,1-4,15-16,18H2,(H,35,40)(H,38,39)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	7.5	22
Novo Nordisk A/S					Assay Description Wheat Germ Agglutinin derivatized SPA beads containing a scintillant (WGA beads) (Amersham) bound the membranes of BHK cells transfected with the hum...				J Med Chem 52: 2989-3000 (2009) Article DOI: 10.1021/jm8016249 BindingDB Entry DOI: 10.7270/Q21Z42RS
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM29128 (aminothiazole, 25) Show SMILES OC(=O)CCNC(=O)c1ccc(cc1)N(Cc1ccc-2c(Cc3ccccc-23)c1)c1nc(cs1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C34H26F3N3O3S/c35-34(36,37)26-10-6-22(7-11-26)30-20-44-33(39-30)40(27-12-8-23(9-13-27)32(43)38-16-15-31(41)42)19-21-5-14-29-25(17-21)18-24-3-1-2-4-28(24)29/h1-14,17,20H,15-16,18-19H2,(H,38,43)(H,41,42)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	78	n/a	n/a	n/a	n/a	7.5	22
Novo Nordisk A/S					Assay Description Wheat Germ Agglutinin derivatized SPA beads containing a scintillant (WGA beads) (Amersham) bound the membranes of BHK cells transfected with the hum...				J Med Chem 52: 2989-3000 (2009) Article DOI: 10.1021/jm8016249 BindingDB Entry DOI: 10.7270/Q21Z42RS
					More data for this Ligand-Target Pair

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