Compile Data Set for Download or QSAR

Found 599 hits with Last Name = 'quesnelle' and Initial = 'c'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Myc proto-oncogene protein (Homo sapiens (Human))	BDBM445524 (2-{7-[4-(2H3)Methyl-1-methyl-1H-1,2,3-triazol-5-yl...) Show SMILES Cc1nnn(C)c1-c1ccc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1cc(cnc21)C(C)(C)O Show InChI InChI=1S/C30H33N5O2/c1-19-28(34(4)33-32-19)22-10-11-24-25(16-22)35(26-17-23(30(2,3)36)18-31-27(24)26)29(20-8-6-5-7-9-20)21-12-14-37-15-13-21/h5-11,16-18,21,29,36H,12-15H2,1-4H3/t29-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of c-MYC (unknown origin)				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128376 BindingDB Entry DOI: 10.7270/Q2KS6WD7
					More data for this Ligand-Target Pair
Bromodomain-containing protein 2 (Homo sapiens (Human))	BDBM297163 (2-{8-Fluoro-3-[4-(2H3)methyl-1-methyl-1H-1,2,3-tri...) Show SMILES Cc1nnn(C)c1-c1cnc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1cc(c(F)cc21)C(C)(C)O |r| Show InChI InChI=1S/C30H32FN5O2/c1-18-28(35(4)34-33-18)21-14-26-27(32-17-21)22-15-24(31)23(30(2,3)37)16-25(22)36(26)29(19-8-6-5-7-9-19)20-10-12-38-13-11-20/h5-9,14-17,20,29,37H,10-13H2,1-4H3/t29-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00219 BindingDB Entry DOI: 10.7270/Q20R9TDX
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM445527 (2-[7-(Dimethyl-1H-1,2,3-triazol-5-yl)-8-fluoro-5-[...) Show SMILES Cc1nnn(C)c1-c1cc2n([C@@H](C3CCOCC3)c3ccccc3)c3cc(cnc3c2cc1F)C(C)(C)O |r,wU:11.11,(5.87,4.1,;5.87,2.56,;7.24,1.86,;7,.34,;5.48,.1,;4.71,-1.23,;4.78,1.47,;3.3,1.87,;2.27,.73,;.76,1.05,;-.49,.14,;-.49,-1.4,;.85,-2.17,;2.18,-1.4,;3.51,-2.17,;3.51,-3.71,;2.18,-4.48,;.85,-3.71,;-1.82,-2.17,;-3.15,-1.4,;-4.49,-2.17,;-4.49,-3.71,;-3.15,-4.48,;-1.82,-3.71,;-1.73,1.05,;-3.24,.73,;-4.27,1.87,;-3.79,3.33,;-2.29,3.65,;-1.26,2.51,;.28,2.51,;1.31,3.65,;2.82,3.33,;3.85,4.48,;-5.76,1.47,;-6.85,2.56,;-6.16,-.02,;-7.24,1.07,)| Show InChI InChI=1S/C30H32FN5O2/c1-18-28(35(4)34-33-18)22-16-25-23(15-24(22)31)27-26(14-21(17-32-27)30(2,3)37)36(25)29(19-8-6-5-7-9-19)20-10-12-38-13-11-20/h5-9,14-17,20,29,37H,10-13H2,1-4H3/t29-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of BRD4 (unknown origin)				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128376 BindingDB Entry DOI: 10.7270/Q2KS6WD7
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50579853 (CHEMBL5075294) Show SMILES [2H]C([2H])([2H])c1nnn(C)c1-c1cc2n([C@@H](CCC)c3ncccc3F)c3cc(cnc3c2cc1F)C(C)(C)O |r,wD:14.18,(54.77,-34.94,;56.32,-34.94,;57.07,-36.27,;55.78,-36.06,;57.04,-33.58,;58.57,-33.38,;58.84,-31.86,;57.49,-31.13,;57.28,-29.61,;56.38,-32.2,;54.86,-31.93,;53.87,-33.1,;52.35,-32.82,;51.14,-33.77,;51.2,-35.31,;49.89,-36.12,;48.54,-35.4,;47.23,-36.21,;52.55,-36.03,;53.85,-35.22,;55.21,-35.93,;55.27,-37.48,;53.96,-38.3,;52.6,-37.57,;51.29,-38.38,;49.87,-32.9,;48.39,-33.26,;47.33,-32.16,;47.76,-30.69,;49.25,-30.33,;50.3,-31.44,;51.84,-31.37,;52.83,-30.2,;54.34,-30.47,;55.33,-29.29,;45.84,-32.53,;45.41,-34.01,;44.34,-32.93,;44.77,-31.42,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of BRD4 (unknown origin)				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128376 BindingDB Entry DOI: 10.7270/Q2KS6WD7
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50579851 (CHEMBL5084198) Show SMILES [2H]C([2H])([2H])c1nnn(C)c1-c1cc2n([C@@H](C3CCOCC3)c3ncccc3F)c3cc(cnc3c2cc1F)C(C)(C)O |r,wD:14.22,(13.75,-33.71,;15.3,-33.71,;16.06,-35.04,;14.76,-34.83,;16.03,-32.35,;17.55,-32.15,;17.83,-30.63,;16.47,-29.9,;16.26,-28.37,;15.36,-30.97,;13.85,-30.69,;12.85,-31.87,;11.34,-31.59,;10.13,-32.54,;10.18,-34.08,;8.87,-34.89,;7.52,-34.16,;6.22,-34.97,;6.26,-36.51,;7.62,-37.24,;8.93,-36.43,;11.54,-34.8,;12.84,-33.99,;14.19,-34.7,;14.25,-36.25,;12.94,-37.06,;11.58,-36.34,;10.27,-37.15,;8.85,-31.67,;7.37,-32.03,;6.32,-30.93,;6.75,-29.46,;8.23,-29.1,;9.29,-30.2,;10.82,-30.14,;11.81,-28.97,;13.32,-29.24,;14.31,-28.06,;4.82,-31.3,;4.39,-32.78,;3.32,-31.69,;3.75,-30.19,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of BRD4 (unknown origin)				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128376 BindingDB Entry DOI: 10.7270/Q2KS6WD7
					More data for this Ligand-Target Pair
Myc proto-oncogene protein (Homo sapiens (Human))	BDBM445528 (2-[7-(Dimethyl-1H-1,2,3-triazol-5-yl)-6-fluoro-5-[...) Show SMILES Cc1nnn(C)c1-c1ccc2c3ncc(cc3n([C@@H](C3CCOCC3)c3ccccc3)c2c1F)C(C)(C)O |r,wU:18.19,(5.87,4.29,;5.87,2.75,;7.24,2.05,;7,.53,;5.48,.29,;4.71,-1.04,;4.78,1.66,;3.3,2.06,;2.82,3.52,;1.31,3.84,;.28,2.7,;-1.26,2.7,;-2.29,3.84,;-3.79,3.52,;-4.27,2.06,;-3.24,.92,;-1.73,1.24,;-.49,.33,;-.49,-1.21,;.85,-1.98,;2.18,-1.21,;3.51,-1.98,;3.51,-3.52,;2.18,-4.29,;.85,-3.52,;-1.82,-1.98,;-3.15,-1.21,;-4.49,-1.98,;-4.49,-3.52,;-3.15,-4.29,;-1.82,-3.52,;.76,1.24,;2.27,.92,;2.74,-.55,;-5.76,1.66,;-6.85,2.75,;-6.16,.17,;-7.24,1.26,)| Show InChI InChI=1S/C30H32FN5O2/c1-18-27(35(4)34-33-18)22-10-11-23-26-24(16-21(17-32-26)30(2,3)37)36(29(23)25(22)31)28(19-8-6-5-7-9-19)20-12-14-38-15-13-20/h5-11,16-17,20,28,37H,12-15H2,1-4H3/t28-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of c-MYC (unknown origin)				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128376 BindingDB Entry DOI: 10.7270/Q2KS6WD7
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50579852 (CHEMBL5090513) Show SMILES [2H]C([2H])([2H])c1nnn(C)c1-c1cc2n([C@@H](C3CCOCC3)c3cc(C)on3)c3cc(cnc3c2cc1F)C(C)(C)O |r,wD:14.22,(33.12,-33.94,;34.66,-33.94,;35.42,-35.27,;34.12,-35.06,;35.39,-32.58,;36.91,-32.38,;37.19,-30.86,;35.83,-30.13,;35.62,-28.61,;34.72,-31.2,;33.21,-30.93,;32.21,-32.1,;30.7,-31.82,;29.49,-32.77,;29.54,-34.31,;28.23,-35.12,;26.88,-34.39,;25.58,-35.2,;25.62,-36.74,;26.98,-37.47,;28.29,-36.66,;30.9,-35.03,;31.11,-36.55,;32.63,-36.82,;33.3,-38.2,;33.35,-35.46,;32.29,-34.35,;28.21,-31.9,;26.73,-32.26,;25.68,-31.16,;26.11,-29.69,;27.6,-29.33,;28.65,-30.44,;30.18,-30.37,;31.17,-29.2,;32.68,-29.47,;33.67,-28.29,;24.18,-31.53,;23.75,-33.01,;22.68,-31.92,;23.12,-30.42,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of BRD4 (unknown origin)				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128376 BindingDB Entry DOI: 10.7270/Q2KS6WD7
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM445524 (2-{7-[4-(2H3)Methyl-1-methyl-1H-1,2,3-triazol-5-yl...) Show SMILES Cc1nnn(C)c1-c1ccc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1cc(cnc21)C(C)(C)O Show InChI InChI=1S/C30H33N5O2/c1-19-28(34(4)33-32-19)22-10-11-24-25(16-22)35(26-17-23(30(2,3)36)18-31-27(24)26)29(20-8-6-5-7-9-20)21-12-14-37-15-13-21/h5-11,16-18,21,29,36H,12-15H2,1-4H3/t29-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of BRD4 (unknown origin)				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128376 BindingDB Entry DOI: 10.7270/Q2KS6WD7
					More data for this Ligand-Target Pair
Myc proto-oncogene protein (Homo sapiens (Human))	BDBM50579853 (CHEMBL5075294) Show SMILES [2H]C([2H])([2H])c1nnn(C)c1-c1cc2n([C@@H](CCC)c3ncccc3F)c3cc(cnc3c2cc1F)C(C)(C)O |r,wD:14.18,(54.77,-34.94,;56.32,-34.94,;57.07,-36.27,;55.78,-36.06,;57.04,-33.58,;58.57,-33.38,;58.84,-31.86,;57.49,-31.13,;57.28,-29.61,;56.38,-32.2,;54.86,-31.93,;53.87,-33.1,;52.35,-32.82,;51.14,-33.77,;51.2,-35.31,;49.89,-36.12,;48.54,-35.4,;47.23,-36.21,;52.55,-36.03,;53.85,-35.22,;55.21,-35.93,;55.27,-37.48,;53.96,-38.3,;52.6,-37.57,;51.29,-38.38,;49.87,-32.9,;48.39,-33.26,;47.33,-32.16,;47.76,-30.69,;49.25,-30.33,;50.3,-31.44,;51.84,-31.37,;52.83,-30.2,;54.34,-30.47,;55.33,-29.29,;45.84,-32.53,;45.41,-34.01,;44.34,-32.93,;44.77,-31.42,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of c-MYC (unknown origin)				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128376 BindingDB Entry DOI: 10.7270/Q2KS6WD7
					More data for this Ligand-Target Pair
Myc proto-oncogene protein (Homo sapiens (Human))	BDBM297146 (2-{3-[4-(2H3)Methyl-1-methyl-1H-1,2,3-triazol-5-yl...) Show SMILES Cc1nnn(C)c1-c1cnc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1cc(ccc21)C(C)(C)O |r| Show InChI InChI=1S/C30H33N5O2/c1-19-28(34(4)33-32-19)22-16-26-27(31-18-22)24-11-10-23(30(2,3)36)17-25(24)35(26)29(20-8-6-5-7-9-20)21-12-14-37-15-13-21/h5-11,16-18,21,29,36H,12-15H2,1-4H3/t29-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of c-MYC (unknown origin)				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128376 BindingDB Entry DOI: 10.7270/Q2KS6WD7
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM445515 (2-[7-(Dimethyl-1H-1,2,3-triazol-5-yl)-9-fluoro-5-[...) Show SMILES Cc1nnn(C)c1-c1cc(F)c2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1cc(cnc21)C(C)(C)O |r| Show InChI InChI=1S/C30H32FN5O2/c1-18-28(35(4)34-33-18)21-14-23(31)26-24(15-21)36(25-16-22(30(2,3)37)17-32-27(25)26)29(19-8-6-5-7-9-19)20-10-12-38-13-11-20/h5-9,14-17,20,29,37H,10-13H2,1-4H3/t29-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of BRD4 (unknown origin)				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128376 BindingDB Entry DOI: 10.7270/Q2KS6WD7
					More data for this Ligand-Target Pair
Myc proto-oncogene protein (Homo sapiens (Human))	BDBM445527 (2-[7-(Dimethyl-1H-1,2,3-triazol-5-yl)-8-fluoro-5-[...) Show SMILES Cc1nnn(C)c1-c1cc2n([C@@H](C3CCOCC3)c3ccccc3)c3cc(cnc3c2cc1F)C(C)(C)O |r,wU:11.11,(5.87,4.1,;5.87,2.56,;7.24,1.86,;7,.34,;5.48,.1,;4.71,-1.23,;4.78,1.47,;3.3,1.87,;2.27,.73,;.76,1.05,;-.49,.14,;-.49,-1.4,;.85,-2.17,;2.18,-1.4,;3.51,-2.17,;3.51,-3.71,;2.18,-4.48,;.85,-3.71,;-1.82,-2.17,;-3.15,-1.4,;-4.49,-2.17,;-4.49,-3.71,;-3.15,-4.48,;-1.82,-3.71,;-1.73,1.05,;-3.24,.73,;-4.27,1.87,;-3.79,3.33,;-2.29,3.65,;-1.26,2.51,;.28,2.51,;1.31,3.65,;2.82,3.33,;3.85,4.48,;-5.76,1.47,;-6.85,2.56,;-6.16,-.02,;-7.24,1.07,)| Show InChI InChI=1S/C30H32FN5O2/c1-18-28(35(4)34-33-18)22-16-25-23(15-24(22)31)27-26(14-21(17-32-27)30(2,3)37)36(25)29(19-8-6-5-7-9-19)20-10-12-38-13-11-20/h5-9,14-17,20,29,37H,10-13H2,1-4H3/t29-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of c-MYC (unknown origin)				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128376 BindingDB Entry DOI: 10.7270/Q2KS6WD7
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM297236 (2-[3-(Dimethyl-1H-1,2,3-triazol-5-yl)-8-methoxy-5-...) Show SMILES COc1cc2c(cc1C(C)(C)O)n([C@@H](C1CCOCC1)c1ccccc1)c1cc(cnc21)-c1c(C)nnn1C |r| Show InChI InChI=1S/C31H35N5O3/c1-19-29(35(4)34-33-19)22-15-26-28(32-18-22)23-16-27(38-5)24(31(2,3)37)17-25(23)36(26)30(20-9-7-6-8-10-20)21-11-13-39-14-12-21/h6-10,15-18,21,30,37H,11-14H2,1-5H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00219 BindingDB Entry DOI: 10.7270/Q20R9TDX
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM297146 (2-{3-[4-(2H3)Methyl-1-methyl-1H-1,2,3-triazol-5-yl...) Show SMILES Cc1nnn(C)c1-c1cnc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1cc(ccc21)C(C)(C)O |r| Show InChI InChI=1S/C30H33N5O2/c1-19-28(34(4)33-32-19)22-16-26-27(31-18-22)24-11-10-23(30(2,3)36)17-25(24)35(26)29(20-8-6-5-7-9-20)21-12-14-37-15-13-21/h5-11,16-18,21,29,36H,12-15H2,1-4H3/t29-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of BRD4 (unknown origin)				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128376 BindingDB Entry DOI: 10.7270/Q2KS6WD7
					More data for this Ligand-Target Pair				3D Structure (crystal)
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM297070 (5-{7-Methanesulfonyl-5-[(S)-oxan-4-yl(phenyl)methy...) Show SMILES Cc1nnn(C)c1-c1cnc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1cc(ccc21)S(C)(=O)=O |r| Show InChI InChI=1S/C28H29N5O3S/c1-18-27(32(2)31-30-18)21-15-25-26(29-17-21)23-10-9-22(37(3,34)35)16-24(23)33(25)28(19-7-5-4-6-8-19)20-11-13-36-14-12-20/h4-10,15-17,20,28H,11-14H2,1-3H3/t28-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00219 BindingDB Entry DOI: 10.7270/Q20R9TDX
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM297163 (2-{8-Fluoro-3-[4-(2H3)methyl-1-methyl-1H-1,2,3-tri...) Show SMILES Cc1nnn(C)c1-c1cnc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1cc(c(F)cc21)C(C)(C)O |r| Show InChI InChI=1S/C30H32FN5O2/c1-18-28(35(4)34-33-18)21-14-26-27(32-17-21)22-15-24(31)23(30(2,3)37)16-25(22)36(26)29(19-8-6-5-7-9-19)20-10-12-38-13-11-20/h5-9,14-17,20,29,37H,10-13H2,1-4H3/t29-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00219 BindingDB Entry DOI: 10.7270/Q20R9TDX
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [1-477] (Homo sapiens (Human))	BDBM445567 (US10683290, Example 66) Show SMILES Cc1nnn(C)c1-c1cc2n(C(CC3COC3)c3ccccc3)c3cc(cnc3c2cc1F)C(C)(C)O |(4.65,-1.19,;5.42,.14,;6.95,.3,;7.27,1.81,;5.94,2.58,;6.34,4.07,;4.79,1.55,;3.29,1.87,;2.26,.73,;.75,1.05,;-.5,.14,;-.5,-1.4,;-1.83,-2.17,;-3.16,-1.4,;-3.56,.09,;-5.05,-.31,;-4.65,-1.8,;.84,-2.17,;.84,-3.71,;2.17,-4.48,;3.51,-3.71,;3.51,-2.17,;2.17,-1.4,;-1.74,1.05,;-3.25,.73,;-4.28,1.87,;-3.8,3.33,;-2.3,3.65,;-1.27,2.51,;.27,2.51,;1.31,3.65,;2.81,3.33,;3.84,4.48,;-5.78,1.55,;-6.81,2.69,;-7.27,1.15,;-6.26,.09,)| Show InChI InChI=1S/C29H30FN5O2/c1-17-28(34(4)33-32-17)21-13-25-22(12-23(21)30)27-26(11-20(14-31-27)29(2,3)36)35(25)24(10-18-15-37-16-18)19-8-6-5-7-9-19/h5-9,11-14,18,24,36H,10,15-16H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description All assay components were dissolved in buffer composition 20 mM Hepes pH 7.5, 150 mM NaCl, 5 mM DTT, 0.005% Tween 20, and 100 ug/ml BSA for BRD4 (1-4...				US Patent US10683290 (2020) BindingDB Entry DOI: 10.7270/Q25D8VWB
					More data for this Ligand-Target Pair
Neurogenic locus notch homolog protein 1 (Homo sapiens (Human))	BDBM50074818 (CHEMBL3410163) Show SMILES CN1c2ccccc2C(=N[C@H](NC(=O)[C@H](CCC(F)(F)F)[C@@H](C(N)=O)c2cccc(c2)C(F)(F)F)C1=O)c1ccccc1 |r,c:9| Show InChI InChI=1S/C30H26F6N4O3/c1-40-22-13-6-5-12-20(22)24(17-8-3-2-4-9-17)38-26(28(40)43)39-27(42)21(14-15-29(31,32)33)23(25(37)41)18-10-7-11-19(16-18)30(34,35)36/h2-13,16,21,23,26H,14-15H2,1H3,(H2,37,41)(H,39,42)/t21-,23+,26-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...				Bioorg Med Chem Lett 25: 1905-9 (2015) Article DOI: 10.1016/j.bmcl.2015.03.038 BindingDB Entry DOI: 10.7270/Q2X92D18
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [1-477] (Homo sapiens (Human))	BDBM445579 (US10683290, Example 72) Show SMILES Cc1nnn(C)c1-c1ccc2c(c1)n([C@@H](C1CCOCC1)c1ncccc1F)c1cc(cnc21)C(C)(C)O |r| Show InChI InChI=1S/C29H31FN6O2/c1-17-27(35(4)34-33-17)19-7-8-21-23(14-19)36(24-15-20(29(2,3)37)16-32-25(21)24)28(18-9-12-38-13-10-18)26-22(30)6-5-11-31-26/h5-8,11,14-16,18,28,37H,9-10,12-13H2,1-4H3/t28-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description All assay components were dissolved in buffer composition 20 mM Hepes pH 7.5, 150 mM NaCl, 5 mM DTT, 0.005% Tween 20, and 100 ug/ml BSA for BRD4 (1-4...				US Patent US10683290 (2020) BindingDB Entry DOI: 10.7270/Q25D8VWB
					More data for this Ligand-Target Pair
Myc proto-oncogene protein (Homo sapiens (Human))	BDBM445527 (2-[7-(Dimethyl-1H-1,2,3-triazol-5-yl)-8-fluoro-5-[...) Show SMILES Cc1nnn(C)c1-c1cc2n([C@@H](C3CCOCC3)c3ccccc3)c3cc(cnc3c2cc1F)C(C)(C)O |r,wU:11.11,(5.87,4.1,;5.87,2.56,;7.24,1.86,;7,.34,;5.48,.1,;4.71,-1.23,;4.78,1.47,;3.3,1.87,;2.27,.73,;.76,1.05,;-.49,.14,;-.49,-1.4,;.85,-2.17,;2.18,-1.4,;3.51,-2.17,;3.51,-3.71,;2.18,-4.48,;.85,-3.71,;-1.82,-2.17,;-3.15,-1.4,;-4.49,-2.17,;-4.49,-3.71,;-3.15,-4.48,;-1.82,-3.71,;-1.73,1.05,;-3.24,.73,;-4.27,1.87,;-3.79,3.33,;-2.29,3.65,;-1.26,2.51,;.28,2.51,;1.31,3.65,;2.82,3.33,;3.85,4.48,;-5.76,1.47,;-6.85,2.56,;-6.16,-.02,;-7.24,1.07,)| Show InChI InChI=1S/C30H32FN5O2/c1-18-28(35(4)34-33-18)22-16-25-23(15-24(22)31)27-26(14-21(17-32-27)30(2,3)37)36(25)29(19-8-6-5-7-9-19)20-10-12-38-13-11-20/h5-9,14-17,20,29,37H,10-13H2,1-4H3/t29-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of c-MYC (unknown origin)				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128376 BindingDB Entry DOI: 10.7270/Q2KS6WD7
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [1-477] (Homo sapiens (Human))	BDBM445578 (US10683290, Example 71) Show SMILES Cc1nnn(C)c1-c1ccc2c(c1)n([C@H](C1CCOCC1)c1ncccc1F)c1cc(cnc21)C(C)(C)O |r| Show InChI InChI=1S/C29H31FN6O2/c1-17-27(35(4)34-33-17)19-7-8-21-23(14-19)36(24-15-20(29(2,3)37)16-32-25(21)24)28(18-9-12-38-13-10-18)26-22(30)6-5-11-31-26/h5-8,11,14-16,18,28,37H,9-10,12-13H2,1-4H3/t28-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description All assay components were dissolved in buffer composition 20 mM Hepes pH 7.5, 150 mM NaCl, 5 mM DTT, 0.005% Tween 20, and 100 ug/ml BSA for BRD4 (1-4...				US Patent US10683290 (2020) BindingDB Entry DOI: 10.7270/Q25D8VWB
					More data for this Ligand-Target Pair
Neurogenic locus notch homolog protein 1 (Homo sapiens (Human))	BDBM50074796 (CHEMBL3410169) Show SMILES CN1c2ccccc2C(=N[C@H](NC(=O)[C@H](CCC(F)(F)F)[C@@H](C(N)=O)c2ccc(F)cc2F)C1=O)c1ccccc1 |r,c:9| Show InChI InChI=1S/C29H25F5N4O3/c1-38-22-10-6-5-9-19(22)24(16-7-3-2-4-8-16)36-26(28(38)41)37-27(40)20(13-14-29(32,33)34)23(25(35)39)18-12-11-17(30)15-21(18)31/h2-12,15,20,23,26H,13-14H2,1H3,(H2,35,39)(H,37,40)/t20-,23+,26-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...				Bioorg Med Chem Lett 25: 1905-9 (2015) Article DOI: 10.1016/j.bmcl.2015.03.038 BindingDB Entry DOI: 10.7270/Q2X92D18
					More data for this Ligand-Target Pair
Neurogenic locus notch homolog protein 3 (Homo sapiens (Human))	BDBM50074771 (CHEMBL3410153) Show SMILES CCC(CC)[C@@H]([C@@H](CCC(F)(F)F)C(=O)N[C@H]1N=C(c2ccccc2)c2ccccc2N(C)C1=O)C(N)=O |r,t:17| Show InChI InChI=1S/C28H33F3N4O3/c1-4-17(5-2)22(24(32)36)20(15-16-28(29,30)31)26(37)34-25-27(38)35(3)21-14-10-9-13-19(21)23(33-25)18-11-7-6-8-12-18/h6-14,17,20,22,25H,4-5,15-16H2,1-3H3,(H2,32,36)(H,34,37)/t20-,22+,25-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of Notch3 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...				Bioorg Med Chem Lett 25: 1905-9 (2015) Article DOI: 10.1016/j.bmcl.2015.03.038 BindingDB Entry DOI: 10.7270/Q2X92D18
					More data for this Ligand-Target Pair
Neurogenic locus notch homolog protein 3 (Homo sapiens (Human))	BDBM50074693 (CHEMBL3410162) Show SMILES CN1c2ccccc2C(=N[C@H](NC(=O)[C@H](CCC(F)(F)F)[C@@H](C(N)=O)c2cccc(C)c2)C1=O)c1ccccc1 |r,c:9| Show InChI InChI=1S/C30H29F3N4O3/c1-18-9-8-12-20(17-18)24(26(34)38)22(15-16-30(31,32)33)28(39)36-27-29(40)37(2)23-14-7-6-13-21(23)25(35-27)19-10-4-3-5-11-19/h3-14,17,22,24,27H,15-16H2,1-2H3,(H2,34,38)(H,36,39)/t22-,24+,27-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of Notch3 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...				Bioorg Med Chem Lett 25: 1905-9 (2015) Article DOI: 10.1016/j.bmcl.2015.03.038 BindingDB Entry DOI: 10.7270/Q2X92D18
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [1-477] (Homo sapiens (Human))	BDBM445545 (US10683290, Example 38) Show SMILES CCCC[C@H](c1ncccc1F)n1c2cc(-c3c(C)nnn3C)c(F)cc2c2ncc(cc12)C(C)(C)O |r,wU:4.12,(6.66,2.22,;5.33,2.99,;4,2.22,;4,.68,;2.66,-.09,;1.33,.68,;1.33,2.22,;-0,2.99,;-1.34,2.22,;-1.34,.68,;-0,-.09,;-0,-1.63,;2.66,-1.63,;1.42,-2.54,;-.09,-2.22,;-1.12,-3.36,;-2.63,-3.04,;-3.77,-4.07,;-3.61,-5.6,;-5.1,-3.3,;-4.78,-1.8,;-3.25,-1.64,;-2.48,-.3,;-.64,-4.83,;-1.67,-5.97,;.86,-5.15,;1.89,-4,;3.43,-4,;4.46,-5.15,;5.97,-4.83,;6.45,-3.36,;5.42,-2.22,;3.91,-2.54,;7.95,-3.04,;9.46,-2.72,;8.27,-4.55,;7.63,-1.54,)| Show InChI InChI=1S/C28H30F2N6O/c1-6-7-10-22(26-20(29)9-8-11-31-26)36-23-14-18(27-16(2)33-34-35(27)5)21(30)13-19(23)25-24(36)12-17(15-32-25)28(3,4)37/h8-9,11-15,22,37H,6-7,10H2,1-5H3/t22-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description All assay components were dissolved in buffer composition 20 mM Hepes pH 7.5, 150 mM NaCl, 5 mM DTT, 0.005% Tween 20, and 100 ug/ml BSA for BRD4 (1-4...				US Patent US10683290 (2020) BindingDB Entry DOI: 10.7270/Q25D8VWB
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [1-477] (Homo sapiens (Human))	BDBM445544 (US10683290, Example 36) Show SMILES Cc1nnn(C)c1-c1cc2n([C@H](C3CCOCC3)c3ccccn3)c3cc(cnc3c2cc1F)C(C)(C)O |r,wU:11.11,(-3.61,-5.6,;-3.77,-4.07,;-5.1,-3.3,;-4.78,-1.8,;-3.25,-1.64,;-2.48,-.3,;-2.63,-3.04,;-1.12,-3.36,;-.09,-2.22,;1.42,-2.54,;2.66,-1.63,;2.66,-.09,;4,.68,;4,2.22,;5.33,2.99,;6.66,2.22,;6.66,.68,;5.33,-.09,;1.33,.68,;-0,-.09,;-1.34,.68,;-1.34,2.22,;-0,2.99,;1.33,2.22,;3.91,-2.54,;5.42,-2.22,;6.45,-3.36,;5.97,-4.83,;4.46,-5.15,;3.43,-4,;1.89,-4,;.86,-5.15,;-.64,-4.83,;-1.67,-5.97,;7.95,-3.04,;9.46,-2.72,;8.27,-4.55,;7.63,-1.54,)| Show InChI InChI=1S/C29H31FN6O2/c1-17-27(35(4)34-33-17)20-15-24-21(14-22(20)30)26-25(13-19(16-32-26)29(2,3)37)36(24)28(18-8-11-38-12-9-18)23-7-5-6-10-31-23/h5-7,10,13-16,18,28,37H,8-9,11-12H2,1-4H3/t28-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description All assay components were dissolved in buffer composition 20 mM Hepes pH 7.5, 150 mM NaCl, 5 mM DTT, 0.005% Tween 20, and 100 ug/ml BSA for BRD4 (1-4...				US Patent US10683290 (2020) BindingDB Entry DOI: 10.7270/Q25D8VWB
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [1-477] (Homo sapiens (Human))	BDBM445542 (2-{8-Fluoro-5-[(5-methyl-1,2-oxazol-3-yl)(oxan-4-y...) Show SMILES Cc1cc(no1)C(C1CCOCC1)n1c2cc(-c3c(C)nnn3C)c(F)cc2c2ncc(cc12)C(C)(C)O |(-.96,3.94,;-.34,2.53,;1.17,2.21,;1.33,.68,;-.08,.05,;-1.11,1.19,;2.66,-.09,;4,.68,;4,2.22,;5.33,2.99,;6.66,2.22,;6.66,.68,;5.33,-.09,;2.66,-1.63,;1.42,-2.54,;-.09,-2.22,;-1.12,-3.36,;-2.63,-3.04,;-3.77,-4.07,;-3.61,-5.6,;-5.1,-3.3,;-4.78,-1.8,;-3.25,-1.64,;-2.48,-.3,;-.64,-4.83,;-1.67,-5.97,;.86,-5.15,;1.89,-4,;3.43,-4,;4.46,-5.15,;5.97,-4.83,;6.45,-3.36,;5.42,-2.22,;3.91,-2.54,;7.95,-3.04,;9.46,-2.72,;8.27,-4.55,;7.63,-1.54,)| Show InChI InChI=1S/C28H31FN6O3/c1-15-10-22(32-38-15)27(17-6-8-37-9-7-17)35-23-13-19(26-16(2)31-33-34(26)5)21(29)12-20(23)25-24(35)11-18(14-30-25)28(3,4)36/h10-14,17,27,36H,6-9H2,1-5H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description All assay components were dissolved in buffer composition 20 mM Hepes pH 7.5, 150 mM NaCl, 5 mM DTT, 0.005% Tween 20, and 100 ug/ml BSA for BRD4 (1-4...				US Patent US10683290 (2020) BindingDB Entry DOI: 10.7270/Q25D8VWB
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [1-477] (Homo sapiens (Human))	BDBM445541 (2-{8-Fluoro-7-[5-(2H3)methyl-3-methyl-1,2-oxazol-4...) Show SMILES Cc1noc(C)c1-c1cc2n([C@@H](C3CCOCC3)c3ccccc3)c3cc(cnc3c2cc1F)C(C)(C)O |wU:11.11,(-3.61,-5.6,;-3.77,-4.07,;-5.1,-3.3,;-4.78,-1.8,;-3.25,-1.64,;-2.48,-.3,;-2.63,-3.04,;-1.12,-3.36,;-.09,-2.22,;1.42,-2.54,;2.66,-1.63,;2.66,-.09,;1.33,.68,;-0,-.09,;-1.34,.68,;-1.34,2.22,;-0,2.99,;1.33,2.22,;4,.68,;4,2.22,;5.33,2.99,;6.66,2.22,;6.66,.68,;5.33,-.09,;3.91,-2.54,;5.42,-2.22,;6.45,-3.36,;5.97,-4.83,;4.46,-5.15,;3.43,-4,;1.89,-4,;.86,-5.15,;-.64,-4.83,;-1.67,-5.97,;7.95,-3.04,;9.46,-2.72,;8.27,-4.55,;7.63,-1.54,)| Show InChI InChI=1S/C31H32FN3O3/c1-18-28(19(2)38-34-18)23-16-26-24(15-25(23)32)29-27(14-22(17-33-29)31(3,4)36)35(26)30(20-8-6-5-7-9-20)21-10-12-37-13-11-21/h5-9,14-17,21,30,36H,10-13H2,1-4H3/t30-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description All assay components were dissolved in buffer composition 20 mM Hepes pH 7.5, 150 mM NaCl, 5 mM DTT, 0.005% Tween 20, and 100 ug/ml BSA for BRD4 (1-4...				US Patent US10683290 (2020) BindingDB Entry DOI: 10.7270/Q25D8VWB
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [1-477] (Homo sapiens (Human))	BDBM445540 (2-{8-Fluoro-7-[4-(2H3)methyl-1-methyl-1H-1,2,3-tri...) Show SMILES Cc1nnn(C)c1-c1cc2n([C@H](C3CCOCC3)c3ccccc3)c3cc(cnc3c2cc1F)C(C)(C)O |wD:11.11,(-3.61,-5.6,;-3.77,-4.07,;-5.1,-3.3,;-4.78,-1.8,;-3.25,-1.64,;-2.48,-.3,;-2.63,-3.04,;-1.12,-3.36,;-.09,-2.22,;1.42,-2.54,;2.66,-1.63,;2.66,-.09,;1.33,.68,;-0,-.09,;-1.34,.68,;-1.34,2.22,;-0,2.99,;1.33,2.22,;4,.68,;4,2.22,;5.33,2.99,;6.66,2.22,;6.66,.68,;5.33,-.09,;3.91,-2.54,;5.42,-2.22,;6.45,-3.36,;5.97,-4.83,;4.46,-5.15,;3.43,-4,;1.89,-4,;.86,-5.15,;-.64,-4.83,;-1.67,-5.97,;7.95,-3.04,;9.46,-2.72,;8.27,-4.55,;7.63,-1.54,)| Show InChI InChI=1S/C30H32FN5O2/c1-18-28(35(4)34-33-18)22-16-25-23(15-24(22)31)27-26(14-21(17-32-27)30(2,3)37)36(25)29(19-8-6-5-7-9-19)20-10-12-38-13-11-20/h5-9,14-17,20,29,37H,10-13H2,1-4H3/t29-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description All assay components were dissolved in buffer composition 20 mM Hepes pH 7.5, 150 mM NaCl, 5 mM DTT, 0.005% Tween 20, and 100 ug/ml BSA for BRD4 (1-4...				US Patent US10683290 (2020) BindingDB Entry DOI: 10.7270/Q25D8VWB
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [1-477] (Homo sapiens (Human))	BDBM445538 (2-{8-Fluoro-5-[(3-fluoropyridin-2-yl)(oxan-4-yl)me...) Show SMILES Cc1nnn(C)c1-c1cc2n(C(C3CCOCC3)c3ncccc3F)c3cc(cnc3c2cc1F)C(C)(C)O |(-3.61,-5.6,;-3.77,-4.07,;-5.1,-3.3,;-4.78,-1.8,;-3.25,-1.64,;-2.48,-.3,;-2.63,-3.04,;-1.12,-3.36,;-.09,-2.22,;1.42,-2.54,;2.66,-1.63,;2.66,-.09,;4,.68,;4,2.22,;5.33,2.99,;6.66,2.22,;6.66,.68,;5.33,-.09,;1.33,.68,;-0,-.09,;-1.34,.68,;-1.34,2.22,;-0,2.99,;1.33,2.22,;2.66,2.99,;3.91,-2.54,;5.42,-2.22,;6.45,-3.36,;5.97,-4.83,;4.46,-5.15,;3.43,-4,;1.89,-4,;.86,-5.15,;-.64,-4.83,;-1.67,-5.97,;7.95,-3.04,;9.46,-2.72,;8.27,-4.55,;7.63,-1.54,)| Show InChI InChI=1S/C29H30F2N6O2/c1-16-27(36(4)35-34-16)19-14-23-20(13-22(19)31)25-24(12-18(15-33-25)29(2,3)38)37(23)28(17-7-10-39-11-8-17)26-21(30)6-5-9-32-26/h5-6,9,12-15,17,28,38H,7-8,10-11H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description All assay components were dissolved in buffer composition 20 mM Hepes pH 7.5, 150 mM NaCl, 5 mM DTT, 0.005% Tween 20, and 100 ug/ml BSA for BRD4 (1-4...				US Patent US10683290 (2020) BindingDB Entry DOI: 10.7270/Q25D8VWB
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [1-477] (Homo sapiens (Human))	BDBM445536 (5-{8-Fluoro-5-[(S)-(2-fluorophenyl)(oxan-4-yl)meth...) Show SMILES Cc1nnn(C)c1-c1cc2n([C@@H](C3CCOCC3)c3ccccc3F)c3cc(cnc3c2cc1F)S(C)(=O)=O |wD:11.11,(-3.61,-5.6,;-3.77,-4.07,;-5.1,-3.3,;-4.78,-1.8,;-3.25,-1.64,;-2.48,-.3,;-2.63,-3.04,;-1.12,-3.36,;-.09,-2.22,;1.42,-2.54,;2.66,-1.63,;2.66,-.09,;4,.68,;4,2.22,;5.33,2.99,;6.66,2.22,;6.66,.68,;5.33,-.09,;1.33,.68,;-0,-.09,;-1.34,.68,;-1.34,2.22,;-0,2.99,;1.33,2.22,;2.66,2.99,;3.91,-2.54,;5.42,-2.22,;6.45,-3.36,;5.97,-4.83,;4.46,-5.15,;3.43,-4,;1.89,-4,;.86,-5.15,;-.64,-4.83,;-1.67,-5.97,;7.95,-3.04,;7.63,-1.54,;9.46,-2.72,;8.27,-4.55,)| Show InChI InChI=1S/C28H27F2N5O3S/c1-16-27(34(2)33-32-16)20-14-24-21(13-23(20)30)26-25(12-18(15-31-26)39(3,36)37)35(24)28(17-8-10-38-11-9-17)19-6-4-5-7-22(19)29/h4-7,12-15,17,28H,8-11H2,1-3H3/t28-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description All assay components were dissolved in buffer composition 20 mM Hepes pH 7.5, 150 mM NaCl, 5 mM DTT, 0.005% Tween 20, and 100 ug/ml BSA for BRD4 (1-4...				US Patent US10683290 (2020) BindingDB Entry DOI: 10.7270/Q25D8VWB
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [1-477] (Homo sapiens (Human))	BDBM445533 (5-{8-Fluoro-5-[(S)-(2-fluorophenyl)(oxan-4-yl)meth...) Show SMILES Cc1nnn(C)c1-c1cc2n([C@@H](C3CCOCC3)c3ccccc3F)c3cc(C)cnc3c2cc1F |r,wU:11.11,(5.3,4.1,;5.3,2.56,;6.67,1.86,;6.43,.34,;4.91,.1,;4.14,-1.23,;4.21,1.47,;2.72,1.87,;1.69,.73,;.19,1.05,;-1.06,.14,;-1.06,-1.4,;.28,-2.17,;1.61,-1.4,;2.94,-2.17,;2.94,-3.71,;1.61,-4.48,;.28,-3.71,;-2.39,-2.17,;-3.73,-1.4,;-5.06,-2.17,;-5.06,-3.71,;-3.73,-4.48,;-2.39,-3.71,;-1.06,-4.48,;-2.3,1.05,;-3.81,.73,;-4.84,1.87,;-6.35,1.55,;-4.36,3.33,;-2.86,3.65,;-1.83,2.51,;-.29,2.51,;.74,3.65,;2.25,3.33,;3.28,4.48,)| Show InChI InChI=1S/C28H27F2N5O/c1-16-12-25-26(31-15-16)21-13-23(30)20(27-17(2)32-33-34(27)3)14-24(21)35(25)28(18-8-10-36-11-9-18)19-6-4-5-7-22(19)29/h4-7,12-15,18,28H,8-11H2,1-3H3/t28-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description All assay components were dissolved in buffer composition 20 mM Hepes pH 7.5, 150 mM NaCl, 5 mM DTT, 0.005% Tween 20, and 100 ug/ml BSA for BRD4 (1-4...				US Patent US10683290 (2020) BindingDB Entry DOI: 10.7270/Q25D8VWB
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [1-477] (Homo sapiens (Human))	BDBM445530 (2-{8-Fluoro-5-[(S)-(2-fluorophenyl)(oxan-4-yl)meth...) Show SMILES Cc1nnn(C)c1-c1cc2n([C@@H](C3CCOCC3)c3ccccc3F)c3cc(cnc3c2cc1F)C(C)(C)O |wD:11.11,(-3.61,-5.6,;-3.77,-4.07,;-5.1,-3.3,;-4.78,-1.8,;-3.25,-1.64,;-2.48,-.3,;-2.63,-3.04,;-1.12,-3.36,;-.09,-2.22,;1.42,-2.54,;2.66,-1.63,;2.66,-.09,;4,.68,;4,2.22,;5.33,2.99,;6.66,2.22,;6.66,.68,;5.33,-.09,;1.33,.68,;-0,-.09,;-1.34,.68,;-1.34,2.22,;-0,2.99,;1.33,2.22,;2.66,2.99,;3.91,-2.54,;5.42,-2.22,;6.45,-3.36,;5.97,-4.83,;4.46,-5.15,;3.43,-4,;1.89,-4,;.86,-5.15,;-.64,-4.83,;-1.67,-5.97,;7.95,-3.04,;9.46,-2.72,;8.27,-4.55,;7.63,-1.54,)| Show InChI InChI=1S/C30H31F2N5O2/c1-17-28(36(4)35-34-17)21-15-25-22(14-24(21)32)27-26(13-19(16-33-27)30(2,3)38)37(25)29(18-9-11-39-12-10-18)20-7-5-6-8-23(20)31/h5-8,13-16,18,29,38H,9-12H2,1-4H3/t29-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description All assay components were dissolved in buffer composition 20 mM Hepes pH 7.5, 150 mM NaCl, 5 mM DTT, 0.005% Tween 20, and 100 ug/ml BSA for BRD4 (1-4...				US Patent US10683290 (2020) BindingDB Entry DOI: 10.7270/Q25D8VWB
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [1-477] (Homo sapiens (Human))	BDBM445529 (2-[7-(Dimethyl-1H-1,2,3-triazol-5-yl)-8-fluoro-5-[...) Show SMILES Cc1nnn(C)c1-c1cc2n([C@@H](C3CCOCC3)c3ccccc3F)c3cc(cnc3c2cc1F)C(C)(C)O |r,wU:11.11,(5.87,4.1,;5.87,2.56,;7.24,1.86,;7,.34,;5.48,.1,;4.71,-1.23,;4.78,1.47,;3.3,1.87,;2.27,.73,;.76,1.05,;-.49,.14,;-.49,-1.4,;.85,-2.17,;2.18,-1.4,;3.51,-2.17,;3.51,-3.71,;2.18,-4.48,;.85,-3.71,;-1.82,-2.17,;-3.15,-1.4,;-4.49,-2.17,;-4.49,-3.71,;-3.15,-4.48,;-1.82,-3.71,;-.49,-4.48,;-1.73,1.05,;-3.24,.73,;-4.27,1.87,;-3.79,3.33,;-2.29,3.65,;-1.26,2.51,;.28,2.51,;1.31,3.65,;2.82,3.33,;3.85,4.48,;-5.76,1.47,;-6.85,2.56,;-6.16,-.02,;-7.24,1.07,)| Show InChI InChI=1S/C30H31F2N5O2/c1-17-28(36(4)35-34-17)21-15-25-22(14-24(21)32)27-26(13-19(16-33-27)30(2,3)38)37(25)29(18-9-11-39-12-10-18)20-7-5-6-8-23(20)31/h5-8,13-16,18,29,38H,9-12H2,1-4H3/t29-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description All assay components were dissolved in buffer composition 20 mM Hepes pH 7.5, 150 mM NaCl, 5 mM DTT, 0.005% Tween 20, and 100 ug/ml BSA for BRD4 (1-4...				US Patent US10683290 (2020) BindingDB Entry DOI: 10.7270/Q25D8VWB
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [1-477] (Homo sapiens (Human))	BDBM445517 (2-[9-Chloro-7-(dimethyl-1H-1,2,3-triazol-5-yl)-5-[...) Show SMILES Cc1nnn(C)c1-c1cc(Cl)c2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1cc(cnc21)C(C)(C)O |r| Show InChI InChI=1S/C30H32ClN5O2/c1-18-28(35(4)34-33-18)21-14-23(31)26-24(15-21)36(25-16-22(30(2,3)37)17-32-27(25)26)29(19-8-6-5-7-9-19)20-10-12-38-13-11-20/h5-9,14-17,20,29,37H,10-13H2,1-4H3/t29-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description All assay components were dissolved in buffer composition 20 mM Hepes pH 7.5, 150 mM NaCl, 5 mM DTT, 0.005% Tween 20, and 100 ug/ml BSA for BRD4 (1-4...				US Patent US10683290 (2020) BindingDB Entry DOI: 10.7270/Q25D8VWB
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [1-477] (Homo sapiens (Human))	BDBM445515 (2-[7-(Dimethyl-1H-1,2,3-triazol-5-yl)-9-fluoro-5-[...) Show SMILES Cc1nnn(C)c1-c1cc(F)c2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1cc(cnc21)C(C)(C)O |r| Show InChI InChI=1S/C30H32FN5O2/c1-18-28(35(4)34-33-18)21-14-23(31)26-24(15-21)36(25-16-22(30(2,3)37)17-32-27(25)26)29(19-8-6-5-7-9-19)20-10-12-38-13-11-20/h5-9,14-17,20,29,37H,10-13H2,1-4H3/t29-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description All assay components were dissolved in buffer composition 20 mM Hepes pH 7.5, 150 mM NaCl, 5 mM DTT, 0.005% Tween 20, and 100 ug/ml BSA for BRD4 (1-4...				US Patent US10683290 (2020) BindingDB Entry DOI: 10.7270/Q25D8VWB
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [1-477] (Homo sapiens (Human))	BDBM445512 (US10683290, Example 8) Show SMILES Cc1nnn(C)c1-c1ccc2c(c1)n(C(C1CCOCC1)c1ccccc1)c1cc(cnc21)C(C)(C)O Show InChI InChI=1S/C30H33N5O2/c1-19-28(34(4)33-32-19)22-10-11-24-25(16-22)35(26-17-23(30(2,3)36)18-31-27(24)26)29(20-8-6-5-7-9-20)21-12-14-37-15-13-21/h5-11,16-18,21,29,36H,12-15H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description All assay components were dissolved in buffer composition 20 mM Hepes pH 7.5, 150 mM NaCl, 5 mM DTT, 0.005% Tween 20, and 100 ug/ml BSA for BRD4 (1-4...				US Patent US10683290 (2020) BindingDB Entry DOI: 10.7270/Q25D8VWB
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [1-477] (Homo sapiens (Human))	BDBM445507 (2-[7-(Dimethyl-1H-1,2,3-triazol-5-yl)-5-[(S)-(4-fl...) Show SMILES Cc1nnn(C)c1-c1ccc2c(c1)n(C(C1CCOCC1)c1ccc(F)cc1)c1cc(cnc21)C(C)(C)O Show InChI InChI=1S/C30H32FN5O2/c1-18-28(35(4)34-33-18)21-7-10-24-25(15-21)36(26-16-22(30(2,3)37)17-32-27(24)26)29(20-11-13-38-14-12-20)19-5-8-23(31)9-6-19/h5-10,15-17,20,29,37H,11-14H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description All assay components were dissolved in buffer composition 20 mM Hepes pH 7.5, 150 mM NaCl, 5 mM DTT, 0.005% Tween 20, and 100 ug/ml BSA for BRD4 (1-4...				US Patent US10683290 (2020) BindingDB Entry DOI: 10.7270/Q25D8VWB
					More data for this Ligand-Target Pair
Neurogenic locus notch homolog protein 2 (Homo sapiens (Human))	BDBM50074694 (CHEMBL3410161) Show SMILES CN1c2ccccc2C(=N[C@H](NC(=O)[C@H](CCC(F)(F)F)[C@@H](C(N)=O)c2ccccc2)C1=O)c1ccccc1 |r,c:9| Show InChI InChI=1S/C29H27F3N4O3/c1-36-22-15-9-8-14-20(22)24(19-12-6-3-7-13-19)34-26(28(36)39)35-27(38)21(16-17-29(30,31)32)23(25(33)37)18-10-4-2-5-11-18/h2-15,21,23,26H,16-17H2,1H3,(H2,33,37)(H,35,38)/t21-,23+,26-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of Notch2 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...				Bioorg Med Chem Lett 25: 1905-9 (2015) Article DOI: 10.1016/j.bmcl.2015.03.038 BindingDB Entry DOI: 10.7270/Q2X92D18
					More data for this Ligand-Target Pair
Neurogenic locus notch homolog protein 3 (Homo sapiens (Human))	BDBM50074796 (CHEMBL3410169) Show SMILES CN1c2ccccc2C(=N[C@H](NC(=O)[C@H](CCC(F)(F)F)[C@@H](C(N)=O)c2ccc(F)cc2F)C1=O)c1ccccc1 |r,c:9| Show InChI InChI=1S/C29H25F5N4O3/c1-38-22-10-6-5-9-19(22)24(16-7-3-2-4-8-16)36-26(28(38)41)37-27(40)20(13-14-29(32,33)34)23(25(35)39)18-12-11-17(30)15-21(18)31/h2-12,15,20,23,26H,13-14H2,1H3,(H2,35,39)(H,37,40)/t20-,23+,26-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of Notch3 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...				Bioorg Med Chem Lett 25: 1905-9 (2015) Article DOI: 10.1016/j.bmcl.2015.03.038 BindingDB Entry DOI: 10.7270/Q2X92D18
					More data for this Ligand-Target Pair
Neurogenic locus notch homolog protein 3 (Homo sapiens (Human))	BDBM50074799 (CHEMBL3410167) Show SMILES CN1c2ccccc2C(=N[C@H](NC(=O)[C@H](CCC(F)(F)F)[C@@H](C(N)=O)c2ccc(F)cc2)C1=O)c1ccccc1 |r,c:9| Show InChI InChI=1S/C29H26F4N4O3/c1-37-22-10-6-5-9-20(22)24(18-7-3-2-4-8-18)35-26(28(37)40)36-27(39)21(15-16-29(31,32)33)23(25(34)38)17-11-13-19(30)14-12-17/h2-14,21,23,26H,15-16H2,1H3,(H2,34,38)(H,36,39)/t21-,23+,26-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of Notch3 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...				Bioorg Med Chem Lett 25: 1905-9 (2015) Article DOI: 10.1016/j.bmcl.2015.03.038 BindingDB Entry DOI: 10.7270/Q2X92D18
					More data for this Ligand-Target Pair
Neurogenic locus notch homolog protein 1 (Homo sapiens (Human))	BDBM50074771 (CHEMBL3410153) Show SMILES CCC(CC)[C@@H]([C@@H](CCC(F)(F)F)C(=O)N[C@H]1N=C(c2ccccc2)c2ccccc2N(C)C1=O)C(N)=O |r,t:17| Show InChI InChI=1S/C28H33F3N4O3/c1-4-17(5-2)22(24(32)36)20(15-16-28(29,30)31)26(37)34-25-27(38)35(3)21-14-10-9-13-19(21)23(33-25)18-11-7-6-8-12-18/h6-14,17,20,22,25H,4-5,15-16H2,1-3H3,(H2,32,36)(H,34,37)/t20-,22+,25-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of Notch1 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...				Bioorg Med Chem Lett 25: 1905-9 (2015) Article DOI: 10.1016/j.bmcl.2015.03.038 BindingDB Entry DOI: 10.7270/Q2X92D18
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50586606 (CHEMBL5080354) Show SMILES Cc1noc(C)c1-c1cc(C(N)=O)c2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1cc(ccc21)C(C)(C)O |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human BRD4 (1 to 477 residues) measured after 60 mins by TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00625 BindingDB Entry DOI: 10.7270/Q2HT2T7C
					More data for this Ligand-Target Pair				3D Structure (crystal)
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM297144 (2-[3-(Dimethyl-1H-1,2,3-triazol-5-yl)-9-methoxy-5-...) Show SMILES COc1cc(cc2n([C@@H](C3CCOCC3)c3ccccc3)c3cc(cnc3c12)-c1c(C)nnn1C)C(C)(C)O |r| Show InChI InChI=1S/C31H35N5O3/c1-19-29(35(4)34-33-19)22-15-25-28(32-18-22)27-24(16-23(31(2,3)37)17-26(27)38-5)36(25)30(20-9-7-6-8-10-20)21-11-13-39-14-12-21/h6-10,15-18,21,30,37H,11-14H2,1-5H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00219 BindingDB Entry DOI: 10.7270/Q20R9TDX
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM297162 (2-{6-Fluoro-3-[4-(2H3)methyl-1-methyl-1H-1,2,3-tri...) Show SMILES Cc1nnn(C)c1-c1cnc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1c(F)c(ccc21)C(C)(C)O |r| Show InChI InChI=1S/C30H32FN5O2/c1-18-27(35(4)34-33-18)21-16-24-26(32-17-21)22-10-11-23(30(2,3)37)25(31)29(22)36(24)28(19-8-6-5-7-9-19)20-12-14-38-15-13-20/h5-11,16-17,20,28,37H,12-15H2,1-4H3/t28-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00219 BindingDB Entry DOI: 10.7270/Q20R9TDX
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM297146 (2-{3-[4-(2H3)Methyl-1-methyl-1H-1,2,3-triazol-5-yl...) Show SMILES Cc1nnn(C)c1-c1cnc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1cc(ccc21)C(C)(C)O |r| Show InChI InChI=1S/C30H33N5O2/c1-19-28(34(4)33-32-19)22-16-26-27(31-18-22)24-11-10-23(30(2,3)36)17-25(24)35(26)29(20-8-6-5-7-9-20)21-12-14-37-15-13-21/h5-11,16-18,21,29,36H,12-15H2,1-4H3/t29-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human BRD4 (1 to 477 residues) measured after 60 mins by TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00625 BindingDB Entry DOI: 10.7270/Q2HT2T7C
					More data for this Ligand-Target Pair				3D Structure (crystal)
Bromodomain-containing protein 3 (Homo sapiens (Human))	BDBM297146 (2-{3-[4-(2H3)Methyl-1-methyl-1H-1,2,3-triazol-5-yl...) Show SMILES Cc1nnn(C)c1-c1cnc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1cc(ccc21)C(C)(C)O |r| Show InChI InChI=1S/C30H33N5O2/c1-19-28(34(4)33-32-19)22-16-26-27(31-18-22)24-11-10-23(30(2,3)36)17-25(24)35(26)29(20-8-6-5-7-9-20)21-12-14-37-15-13-21/h5-11,16-18,21,29,36H,12-15H2,1-4H3/t29-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human BRD3 measured by TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00625 BindingDB Entry DOI: 10.7270/Q2HT2T7C
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM297146 (2-{3-[4-(2H3)Methyl-1-methyl-1H-1,2,3-triazol-5-yl...) Show SMILES Cc1nnn(C)c1-c1cnc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1cc(ccc21)C(C)(C)O |r| Show InChI InChI=1S/C30H33N5O2/c1-19-28(34(4)33-32-19)22-16-26-27(31-18-22)24-11-10-23(30(2,3)36)17-25(24)35(26)29(20-8-6-5-7-9-20)21-12-14-37-15-13-21/h5-11,16-18,21,29,36H,12-15H2,1-4H3/t29-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00219 BindingDB Entry DOI: 10.7270/Q20R9TDX
					More data for this Ligand-Target Pair				3D Structure (crystal)
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM297268 (2-{6-Chloro-3-[4-(2H3)methyl-1-methyl-1H-1,2,3-tri...) Show SMILES Cc1nnn(C)c1-c1cnc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1c(Cl)c(ccc21)C(C)(C)O |r| Show InChI InChI=1S/C30H32ClN5O2/c1-18-27(35(4)34-33-18)21-16-24-26(32-17-21)22-10-11-23(30(2,3)37)25(31)29(22)36(24)28(19-8-6-5-7-9-19)20-12-14-38-15-13-20/h5-11,16-17,20,28,37H,12-15H2,1-4H3/t28-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00219 BindingDB Entry DOI: 10.7270/Q20R9TDX
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM297146 (2-{3-[4-(2H3)Methyl-1-methyl-1H-1,2,3-triazol-5-yl...) Show SMILES Cc1nnn(C)c1-c1cnc2c(c1)n([C@@H](C1CCOCC1)c1ccccc1)c1cc(ccc21)C(C)(C)O |r| Show InChI InChI=1S/C30H33N5O2/c1-19-28(34(4)33-32-19)22-16-26-27(31-18-22)24-11-10-23(30(2,3)36)17-25(24)35(26)29(20-8-6-5-7-9-20)21-12-14-37-15-13-21/h5-11,16-18,21,29,36H,12-15H2,1-4H3/t29-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acsmedchemlett.2c00219 BindingDB Entry DOI: 10.7270/Q20R9TDX
					More data for this Ligand-Target Pair				3D Structure (crystal)

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