Compile Data Set for Download or QSAR

Found 186 hits with Last Name = 'riccioni' and Initial = 't'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis				Eur J Med Chem 80: 8-35 (2014) Article DOI: 10.1016/j.ejmech.2014.04.034 BindingDB Entry DOI: 10.7270/Q2HT2QV6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50015025 (CHEMBL3262408) Show SMILES CN(CCCN1CCN(CC1)c1cccc2ccccc12)c1cccc(O)c1 Show InChI InChI=1S/C24H29N3O/c1-25(21-9-5-10-22(28)19-21)13-6-14-26-15-17-27(18-16-26)24-12-4-8-20-7-2-3-11-23(20)24/h2-5,7-12,19,28H,6,13-18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis				Eur J Med Chem 80: 8-35 (2014) Article DOI: 10.1016/j.ejmech.2014.04.034 BindingDB Entry DOI: 10.7270/Q2HT2QV6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50015219 (CHEMBL3262410) Show SMILES Oc1cccc(CCCCN2CCN(CC2)c2ccccc2)c1 Show InChI InChI=1S/C20H26N2O/c23-20-11-6-8-18(17-20)7-4-5-12-21-13-15-22(16-14-21)19-9-2-1-3-10-19/h1-3,6,8-11,17,23H,4-5,7,12-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis				Eur J Med Chem 80: 8-35 (2014) Article DOI: 10.1016/j.ejmech.2014.04.034 BindingDB Entry DOI: 10.7270/Q2HT2QV6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50015221 (CHEMBL3262395) Show SMILES CCc1[nH]c2ccc(O)cc2c1CCN1CCN(CC1)c1cccc2ccccc12 Show InChI InChI=1S/C26H29N3O/c1-2-24-22(23-18-20(30)10-11-25(23)27-24)12-13-28-14-16-29(17-15-28)26-9-5-7-19-6-3-4-8-21(19)26/h3-11,18,27,30H,2,12-17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis				Eur J Med Chem 80: 8-35 (2014) Article DOI: 10.1016/j.ejmech.2014.04.034 BindingDB Entry DOI: 10.7270/Q2HT2QV6
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM181012 (US9133197, 4) Show SMILES C[C@@H](O)CCc1nc(N)c2nc(-n3nccn3)n(C)c2n1 Show InChI InChI=1S/C12H16N8O/c1-7(21)3-4-8-16-10(13)9-11(17-8)19(2)12(18-9)20-14-5-6-15-20/h5-7,21H,3-4H2,1-2H3,(H2,13,16,17)/t7-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	7.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Displacement of [3H]ZM241385 from human recombinant adenosine A2A receptor expressed in HEK293 cells after 1 hr by competitive binding assay				J Med Chem 56: 5456-63 (2013) Article DOI: 10.1021/jm400491x BindingDB Entry DOI: 10.7270/Q2R49TQK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50015197 (CHEMBL3262432) Show SMILES Cl.CN(C(=O)CCCCCN1CCN(CC1)c1cccc2ccccc12)c1cccc(O)c1 Show InChI InChI=1S/C27H33N3O2.ClH/c1-28(23-11-8-12-24(31)21-23)27(32)15-3-2-6-16-29-17-19-30(20-18-29)26-14-7-10-22-9-4-5-13-25(22)26;/h4-5,7-14,21,31H,2-3,6,15-20H2,1H3;1H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	8.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Binding affinity to human recombinant 5-HT7 receptor expressed in CHO cells after 30 mins by radioligand displacement assay				Eur J Med Chem 80: 8-35 (2014) Article DOI: 10.1016/j.ejmech.2014.04.034 BindingDB Entry DOI: 10.7270/Q2HT2QV6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50015197 (CHEMBL3262432) Show SMILES Cl.CN(C(=O)CCCCCN1CCN(CC1)c1cccc2ccccc12)c1cccc(O)c1 Show InChI InChI=1S/C27H33N3O2.ClH/c1-28(23-11-8-12-24(31)21-23)27(32)15-3-2-6-16-29-17-19-30(20-18-29)26-14-7-10-22-9-4-5-13-25(22)26;/h4-5,7-14,21,31H,2-3,6,15-20H2,1H3;1H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	8.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis				Eur J Med Chem 80: 8-35 (2014) Article DOI: 10.1016/j.ejmech.2014.04.034 BindingDB Entry DOI: 10.7270/Q2HT2QV6
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50011300 (CHEMBL2398482 | US9133197, 2) Show SMILES CC(O)CCc1nc(N)c2nc(-n3nccn3)n(C)c2n1 Show InChI InChI=1S/C12H16N8O/c1-7(21)3-4-8-16-10(13)9-11(17-8)19(2)12(18-9)20-14-5-6-15-20/h5-7,21H,3-4H2,1-2H3,(H2,13,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	8.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Displacement of [3H]ZM241385 from human recombinant adenosine A2A receptor expressed in HEK293 cells after 1 hr by competitive binding assay				J Med Chem 56: 5456-63 (2013) Article DOI: 10.1021/jm400491x BindingDB Entry DOI: 10.7270/Q2R49TQK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50015024 (CHEMBL3262411) Show SMILES Oc1cccc(NCCCN2CCN(CC2)c2ccccc2)c1 Show InChI InChI=1S/C19H25N3O/c23-19-9-4-6-17(16-19)20-10-5-11-21-12-14-22(15-13-21)18-7-2-1-3-8-18/h1-4,6-9,16,20,23H,5,10-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis				Eur J Med Chem 80: 8-35 (2014) Article DOI: 10.1016/j.ejmech.2014.04.034 BindingDB Entry DOI: 10.7270/Q2HT2QV6
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50176058 (2-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-...) Show SMILES CCCCc1nc(N)c2nc(-n3nccn3)n(C)c2n1 Show InChI InChI=1S/C12H16N8/c1-3-4-5-8-16-10(13)9-11(17-8)19(2)12(18-9)20-14-6-7-15-20/h6-7H,3-5H2,1-2H3,(H2,13,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Displacement of [3H]ZM241385 from human recombinant adenosine A2A receptor expressed in HEK293 cells after 1 hr by competitive binding assay				J Med Chem 56: 5456-63 (2013) Article DOI: 10.1021/jm400491x BindingDB Entry DOI: 10.7270/Q2R49TQK
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50011301 (CHEMBL2398486 | US9133197, 7) Show SMILES CC(=O)CCc1nc(N)c2nc(-n3nccn3)n(C)c2n1 Show InChI InChI=1S/C12H14N8O/c1-7(21)3-4-8-16-10(13)9-11(17-8)19(2)12(18-9)20-14-5-6-15-20/h5-6H,3-4H2,1-2H3,(H2,13,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Displacement of [3H]ZM241385 from human recombinant adenosine A2A receptor expressed in HEK293 cells after 1 hr by competitive binding assay				J Med Chem 56: 5456-63 (2013) Article DOI: 10.1021/jm400491x BindingDB Entry DOI: 10.7270/Q2R49TQK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50015220 (CHEMBL3262393) Show SMILES Oc1ccc2[nH]cc(CCN3CCN(CC3)c3cccc4ccccc34)c2c1 Show InChI InChI=1S/C24H25N3O/c28-20-8-9-23-22(16-20)19(17-25-23)10-11-26-12-14-27(15-13-26)24-7-3-5-18-4-1-2-6-21(18)24/h1-9,16-17,25,28H,10-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis				Eur J Med Chem 80: 8-35 (2014) Article DOI: 10.1016/j.ejmech.2014.04.034 BindingDB Entry DOI: 10.7270/Q2HT2QV6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50015220 (CHEMBL3262393) Show SMILES Oc1ccc2[nH]cc(CCN3CCN(CC3)c3cccc4ccccc34)c2c1 Show InChI InChI=1S/C24H25N3O/c28-20-8-9-23-22(16-20)19(17-25-23)10-11-26-12-14-27(15-13-26)24-7-3-5-18-4-1-2-6-21(18)24/h1-9,16-17,25,28H,10-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Binding affinity to human recombinant 5-HT7 receptor expressed in CHO cells after 30 mins by radioligand displacement assay				Eur J Med Chem 80: 8-35 (2014) Article DOI: 10.1016/j.ejmech.2014.04.034 BindingDB Entry DOI: 10.7270/Q2HT2QV6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50015015 (CHEMBL3262425) Show SMILES Oc1cccc(c1)N(CCCN1CCN(CC1)c1ccccc1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C25H29N3O3S/c29-24-12-7-11-23(21-24)28(32(30,31)25-13-5-2-6-14-25)16-8-15-26-17-19-27(20-18-26)22-9-3-1-4-10-22/h1-7,9-14,21,29H,8,15-20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis				Eur J Med Chem 80: 8-35 (2014) Article DOI: 10.1016/j.ejmech.2014.04.034 BindingDB Entry DOI: 10.7270/Q2HT2QV6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50015200 (CHEMBL3262430) Show SMILES CN(CCCCCCN1CCN(CC1)c1ccccc1)c1cccc(O)c1 Show InChI InChI=1S/C23H33N3O/c1-24(22-12-9-13-23(27)20-22)14-7-2-3-8-15-25-16-18-26(19-17-25)21-10-5-4-6-11-21/h4-6,9-13,20,27H,2-3,7-8,14-19H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis				Eur J Med Chem 80: 8-35 (2014) Article DOI: 10.1016/j.ejmech.2014.04.034 BindingDB Entry DOI: 10.7270/Q2HT2QV6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50015222 (CHEMBL3262394) Show SMILES Cc1[nH]c2ccc(O)cc2c1CCN1CCN(CC1)c1cccc2ccccc12 Show InChI InChI=1S/C25H27N3O/c1-18-21(23-17-20(29)9-10-24(23)26-18)11-12-27-13-15-28(16-14-27)25-8-4-6-19-5-2-3-7-22(19)25/h2-10,17,26,29H,11-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis				Eur J Med Chem 80: 8-35 (2014) Article DOI: 10.1016/j.ejmech.2014.04.034 BindingDB Entry DOI: 10.7270/Q2HT2QV6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50015033 (CHEMBL3262421) Show SMILES O=Cc1cccc(NCCCN2CCN(CC2)c2ccccc2)c1 Show InChI InChI=1S/C20H25N3O/c24-17-18-6-4-7-19(16-18)21-10-5-11-22-12-14-23(15-13-22)20-8-2-1-3-9-20/h1-4,6-9,16-17,21H,5,10-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis				Eur J Med Chem 80: 8-35 (2014) Article DOI: 10.1016/j.ejmech.2014.04.034 BindingDB Entry DOI: 10.7270/Q2HT2QV6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50015199 (CHEMBL3262429) Show SMILES CN(CCCCCN1CCN(CC1)c1ccccc1)c1cccc(O)c1 Show InChI InChI=1S/C22H31N3O/c1-23(21-11-8-12-22(26)19-21)13-6-3-7-14-24-15-17-25(18-16-24)20-9-4-2-5-10-20/h2,4-5,8-12,19,26H,3,6-7,13-18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis				Eur J Med Chem 80: 8-35 (2014) Article DOI: 10.1016/j.ejmech.2014.04.034 BindingDB Entry DOI: 10.7270/Q2HT2QV6
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Rattus norvegicus (rat))	BDBM50047166 (8-[(E)-2-(3,4-Dimethoxy-phenyl)-vinyl]-1,3,7-trime...) Show SMILES COc1ccc(\C=C\c2nc3n(C)c(=O)n(C)c(=O)c3n2C)cc1OC Show InChI InChI=1S/C18H20N4O4/c1-20-14(9-7-11-6-8-12(25-4)13(10-11)26-5)19-16-15(20)17(23)22(3)18(24)21(16)2/h6-10H,1-5H3/b9-7+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Binding affinity to A2A receptor in rat brain striatal membrane by radioligand displacement assay				J Med Chem 56: 1247-61 (2013) Article DOI: 10.1021/jm301686s BindingDB Entry DOI: 10.7270/Q2SB472H
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM181011 (US9133197, 3) Show SMILES C[C@H](O)CCc1nc(N)c2nc(-n3nccn3)n(C)c2n1 Show InChI InChI=1S/C12H16N8O/c1-7(21)3-4-8-16-10(13)9-11(17-8)19(2)12(18-9)20-14-5-6-15-20/h5-7,21H,3-4H2,1-2H3,(H2,13,16,17)/t7-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Displacement of [3H]ZM241385 from human recombinant adenosine A2A receptor expressed in HEK293 cells after 1 hr by competitive binding assay				J Med Chem 56: 5456-63 (2013) Article DOI: 10.1021/jm400491x BindingDB Entry DOI: 10.7270/Q2R49TQK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50015027 (CHEMBL3262407) Show SMILES CN(CCCN1CCN(CC1)c1ccccc1)c1cccc(O)c1 Show InChI InChI=1S/C20H27N3O/c1-21(19-9-5-10-20(24)17-19)11-6-12-22-13-15-23(16-14-22)18-7-3-2-4-8-18/h2-5,7-10,17,24H,6,11-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Binding affinity to human recombinant 5-HT7 receptor expressed in CHO cells after 30 mins by radioligand displacement assay				Eur J Med Chem 80: 8-35 (2014) Article DOI: 10.1016/j.ejmech.2014.04.034 BindingDB Entry DOI: 10.7270/Q2HT2QV6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50015027 (CHEMBL3262407) Show SMILES CN(CCCN1CCN(CC1)c1ccccc1)c1cccc(O)c1 Show InChI InChI=1S/C20H27N3O/c1-21(19-9-5-10-20(24)17-19)11-6-12-22-13-15-23(16-14-22)18-7-3-2-4-8-18/h2-5,7-10,17,24H,6,11-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis				Eur J Med Chem 80: 8-35 (2014) Article DOI: 10.1016/j.ejmech.2014.04.034 BindingDB Entry DOI: 10.7270/Q2HT2QV6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50015012 (CHEMBL3262422) Show SMILES CCCN(CCCN1CCN(CC1)c1ccccc1)c1cccc(O)c1 Show InChI InChI=1S/C22H31N3O/c1-2-12-24(21-10-6-11-22(26)19-21)14-7-13-23-15-17-25(18-16-23)20-8-4-3-5-9-20/h3-6,8-11,19,26H,2,7,12-18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis				Eur J Med Chem 80: 8-35 (2014) Article DOI: 10.1016/j.ejmech.2014.04.034 BindingDB Entry DOI: 10.7270/Q2HT2QV6
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM181013 (US9133197, 5) Show SMILES CCCC(O)c1nc(N)c2nc(-n3nccn3)n(C)c2n1 Show InChI InChI=1S/C12H16N8O/c1-3-4-7(21)10-17-9(13)8-11(18-10)19(2)12(16-8)20-14-5-6-15-20/h5-7,21H,3-4H2,1-2H3,(H2,13,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Displacement of [3H]ZM241385 from human recombinant adenosine A2A receptor expressed in HEK293 cells after 1 hr by competitive binding assay				J Med Chem 56: 5456-63 (2013) Article DOI: 10.1021/jm400491x BindingDB Entry DOI: 10.7270/Q2R49TQK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50015198 (CHEMBL3262428) Show SMILES CN(CCCCN1CCN(CC1)c1ccccc1)c1cccc(O)c1 Show InChI InChI=1S/C21H29N3O/c1-22(20-10-7-11-21(25)18-20)12-5-6-13-23-14-16-24(17-15-23)19-8-3-2-4-9-19/h2-4,7-11,18,25H,5-6,12-17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis				Eur J Med Chem 80: 8-35 (2014) Article DOI: 10.1016/j.ejmech.2014.04.034 BindingDB Entry DOI: 10.7270/Q2HT2QV6
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50011300 (CHEMBL2398482 | US9133197, 2) Show SMILES CC(O)CCc1nc(N)c2nc(-n3nccn3)n(C)c2n1 Show InChI InChI=1S/C12H16N8O/c1-7(21)3-4-8-16-10(13)9-11(17-8)19(2)12(18-9)20-14-5-6-15-20/h5-7,21H,3-4H2,1-2H3,(H2,13,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from human recombinant adenosine A1 receptor expressed in CHO-K1 cells after 60 mins				J Med Chem 56: 5456-63 (2013) Article DOI: 10.1021/jm400491x BindingDB Entry DOI: 10.7270/Q2R49TQK
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM181012 (US9133197, 4) Show SMILES C[C@@H](O)CCc1nc(N)c2nc(-n3nccn3)n(C)c2n1 Show InChI InChI=1S/C12H16N8O/c1-7(21)3-4-8-16-10(13)9-11(17-8)19(2)12(18-9)20-14-5-6-15-20/h5-7,21H,3-4H2,1-2H3,(H2,13,16,17)/t7-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from human recombinant adenosine A1 receptor expressed in CHO-K1 cells after 60 mins				J Med Chem 56: 5456-63 (2013) Article DOI: 10.1021/jm400491x BindingDB Entry DOI: 10.7270/Q2R49TQK
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Rattus norvegicus (rat))	BDBM50061950 (8-((E)-2-Benzo[1,3]dioxol-5-yl-vinyl)-3,7-dimethyl...) Show SMILES Cn1c(\C=C\c2ccc3OCOc3c2)nc2n(C)c(=O)n(CC#C)c(=O)c12 Show InChI InChI=1S/C19H16N4O4/c1-4-9-23-18(24)16-17(22(3)19(23)25)20-15(21(16)2)8-6-12-5-7-13-14(10-12)27-11-26-13/h1,5-8,10H,9,11H2,2-3H3/b8-6+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Binding affinity to A2A receptor in rat brain striatal membrane by radioligand displacement assay				J Med Chem 56: 1247-61 (2013) Article DOI: 10.1021/jm301686s BindingDB Entry DOI: 10.7270/Q2SB472H
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Rattus norvegicus (rat))	BDBM50037429 (8-(3-chlorostyryl)caffeine | 8-[(E)-2-(3-chlorophe...) Show SMILES Cn1c(\C=C\c2cccc(Cl)c2)nc2n(C)c(=O)n(C)c(=O)c12 Show InChI InChI=1S/C16H15ClN4O2/c1-19-12(8-7-10-5-4-6-11(17)9-10)18-14-13(19)15(22)21(3)16(23)20(14)2/h4-9H,1-3H3/b8-7+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Binding affinity to A2A receptor in rat brain striatal membrane by radioligand displacement assay				J Med Chem 56: 1247-61 (2013) Article DOI: 10.1021/jm301686s BindingDB Entry DOI: 10.7270/Q2SB472H
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50015211 (CHEMBL3259846) Show SMILES Cl.CN(CCCCCCN1CCN(CC1)c1cccc2ccccc12)c1cccc(O)c1 Show InChI InChI=1S/C27H35N3O.ClH/c1-28(24-12-9-13-25(31)22-24)16-6-2-3-7-17-29-18-20-30(21-19-29)27-15-8-11-23-10-4-5-14-26(23)27;/h4-5,8-15,22,31H,2-3,6-7,16-21H2,1H3;1H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis				Eur J Med Chem 80: 8-35 (2014) Article DOI: 10.1016/j.ejmech.2014.04.034 BindingDB Entry DOI: 10.7270/Q2HT2QV6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50015218 (CHEMBL3262406) Show SMILES Cl.Oc1cccc(CCCN2CCN(CC2)c2ccccc2)c1 Show InChI InChI=1S/C19H24N2O.ClH/c22-19-10-4-6-17(16-19)7-5-11-20-12-14-21(15-13-20)18-8-2-1-3-9-18;/h1-4,6,8-10,16,22H,5,7,11-15H2;1H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis				Eur J Med Chem 80: 8-35 (2014) Article DOI: 10.1016/j.ejmech.2014.04.034 BindingDB Entry DOI: 10.7270/Q2HT2QV6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50015029 (CHEMBL3262417) Show SMILES CN(CCCN1CCN(CC1)c1ccccc1)c1cccc(NS(C)(=O)=O)c1 Show InChI InChI=1S/C21H30N4O2S/c1-23(21-11-6-8-19(18-21)22-28(2,26)27)12-7-13-24-14-16-25(17-15-24)20-9-4-3-5-10-20/h3-6,8-11,18,22H,7,12-17H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis				Eur J Med Chem 80: 8-35 (2014) Article DOI: 10.1016/j.ejmech.2014.04.034 BindingDB Entry DOI: 10.7270/Q2HT2QV6
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50176050 (8-(3,4-dimethoxystyryl)-1,3-diethyl-7-methyl-1H-pu...) Show SMILES CCn1c2nc(\C=C\c3ccc(OC)c(OC)c3)n(C)c2c(=O)n(CC)c1=O Show InChI InChI=1S/C20H24N4O4/c1-6-23-18-17(19(25)24(7-2)20(23)26)22(3)16(21-18)11-9-13-8-10-14(27-4)15(12-13)28-5/h8-12H,6-7H2,1-5H3/b11-9+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cells after 1 hr by microbeta scintillation counting analysis				J Med Chem 56: 1247-61 (2013) Article DOI: 10.1021/jm301686s BindingDB Entry DOI: 10.7270/Q2SB472H
					More data for this Ligand-Target Pair				3D Structure (crystal)
Adenosine receptor A2a (Homo sapiens (Human))	BDBM181010 (US9133197, 1) Show SMILES Cn1c(nc2c(N)nc(CCCCO)nc12)-n1nccn1 Show InChI InChI=1S/C12H16N8O/c1-19-11-9(18-12(19)20-14-5-6-15-20)10(13)16-8(17-11)4-2-3-7-21/h5-6,21H,2-4,7H2,1H3,(H2,13,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Displacement of [3H]ZM241385 from human recombinant adenosine A2A receptor expressed in HEK293 cells after 1 hr by competitive binding assay				J Med Chem 56: 5456-63 (2013) Article DOI: 10.1021/jm400491x BindingDB Entry DOI: 10.7270/Q2R49TQK
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM181011 (US9133197, 3) Show SMILES C[C@H](O)CCc1nc(N)c2nc(-n3nccn3)n(C)c2n1 Show InChI InChI=1S/C12H16N8O/c1-7(21)3-4-8-16-10(13)9-11(17-8)19(2)12(18-9)20-14-5-6-15-20/h5-7,21H,3-4H2,1-2H3,(H2,13,16,17)/t7-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from human recombinant adenosine A1 receptor expressed in CHO-K1 cells after 60 mins				J Med Chem 56: 5456-63 (2013) Article DOI: 10.1021/jm400491x BindingDB Entry DOI: 10.7270/Q2R49TQK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50015019 (CHEMBL3262402) Show SMILES Cl.CN(CCN1CCN(CC1)c1ccccc1)c1cccc(NS(C)(=O)=O)c1 Show InChI InChI=1S/C20H28N4O2S.ClH/c1-22(20-10-6-7-18(17-20)21-27(2,25)26)11-12-23-13-15-24(16-14-23)19-8-4-3-5-9-19;/h3-10,17,21H,11-16H2,1-2H3;1H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis				Eur J Med Chem 80: 8-35 (2014) Article DOI: 10.1016/j.ejmech.2014.04.034 BindingDB Entry DOI: 10.7270/Q2HT2QV6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50015030 (CHEMBL3262420) Show SMILES NC(=O)c1cccc(NCCCN2CCN(CC2)c2ccccc2)c1 Show InChI InChI=1S/C20H26N4O/c21-20(25)17-6-4-7-18(16-17)22-10-5-11-23-12-14-24(15-13-23)19-8-2-1-3-9-19/h1-4,6-9,16,22H,5,10-15H2,(H2,21,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis				Eur J Med Chem 80: 8-35 (2014) Article DOI: 10.1016/j.ejmech.2014.04.034 BindingDB Entry DOI: 10.7270/Q2HT2QV6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50015223 (CHEMBL3262390) Show SMILES Oc1ccc2[nH]cc(CCN3CCN(CC3)c3ccccc3)c2c1 Show InChI InChI=1S/C20H23N3O/c24-18-6-7-20-19(14-18)16(15-21-20)8-9-22-10-12-23(13-11-22)17-4-2-1-3-5-17/h1-7,14-15,21,24H,8-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis				Eur J Med Chem 80: 8-35 (2014) Article DOI: 10.1016/j.ejmech.2014.04.034 BindingDB Entry DOI: 10.7270/Q2HT2QV6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50015223 (CHEMBL3262390) Show SMILES Oc1ccc2[nH]cc(CCN3CCN(CC3)c3ccccc3)c2c1 Show InChI InChI=1S/C20H23N3O/c24-18-6-7-20-19(14-18)16(15-21-20)8-9-22-10-12-23(13-11-22)17-4-2-1-3-5-17/h1-7,14-15,21,24H,8-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Binding affinity to human recombinant 5-HT7 receptor expressed in CHO cells after 30 mins by radioligand displacement assay				Eur J Med Chem 80: 8-35 (2014) Article DOI: 10.1016/j.ejmech.2014.04.034 BindingDB Entry DOI: 10.7270/Q2HT2QV6
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50492322 (CHEMBL2398481) Show SMILES CCC(O)Cc1nc(N)c2nc(-n3nccn3)n(C)c2n1 Show InChI InChI=1S/C12H16N8O/c1-3-7(21)6-8-16-10(13)9-11(17-8)19(2)12(18-9)20-14-4-5-15-20/h4-5,7,21H,3,6H2,1-2H3,(H2,13,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	64	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Displacement of [3H]ZM241385 from human recombinant adenosine A2A receptor expressed in HEK293 cells after 1 hr by competitive binding assay				J Med Chem 56: 5456-63 (2013) Article DOI: 10.1021/jm400491x BindingDB Entry DOI: 10.7270/Q2R49TQK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50015031 (CHEMBL3262419) Show SMILES COC(=O)c1cccc(NCCCN2CCN(CC2)c2ccccc2)c1 Show InChI InChI=1S/C21H27N3O2/c1-26-21(25)18-7-5-8-19(17-18)22-11-6-12-23-13-15-24(16-14-23)20-9-3-2-4-10-20/h2-5,7-10,17,22H,6,11-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	78	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis				Eur J Med Chem 80: 8-35 (2014) Article DOI: 10.1016/j.ejmech.2014.04.034 BindingDB Entry DOI: 10.7270/Q2HT2QV6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50015016 (CHEMBL3262398) Show SMILES Oc1cccc2CCC(Cc12)N1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C20H24N2O/c23-20-8-4-5-16-9-10-18(15-19(16)20)22-13-11-21(12-14-22)17-6-2-1-3-7-17/h1-8,18,23H,9-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	81	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis				Eur J Med Chem 80: 8-35 (2014) Article DOI: 10.1016/j.ejmech.2014.04.034 BindingDB Entry DOI: 10.7270/Q2HT2QV6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50015020 (CHEMBL3262412) Show SMILES CN(CCCN1CCN(CC1)c1ccccc1)c1cccc(C)c1 Show InChI InChI=1S/C21H29N3/c1-19-8-6-11-21(18-19)22(2)12-7-13-23-14-16-24(17-15-23)20-9-4-3-5-10-20/h3-6,8-11,18H,7,12-17H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	85	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis				Eur J Med Chem 80: 8-35 (2014) Article DOI: 10.1016/j.ejmech.2014.04.034 BindingDB Entry DOI: 10.7270/Q2HT2QV6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50015014 (CHEMBL3262423) Show SMILES Oc1cccc(c1)N(CCCN1CCN(CC1)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H29N3O/c29-25-14-7-13-24(21-25)28(23-11-5-2-6-12-23)16-8-15-26-17-19-27(20-18-26)22-9-3-1-4-10-22/h1-7,9-14,21,29H,8,15-20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis				Eur J Med Chem 80: 8-35 (2014) Article DOI: 10.1016/j.ejmech.2014.04.034 BindingDB Entry DOI: 10.7270/Q2HT2QV6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50015013 (CHEMBL3262424) Show SMILES Oc1cccc(c1)N(CCCN1CCN(CC1)c1ccccc1)Cc1ccccc1 Show InChI InChI=1S/C26H31N3O/c30-26-14-7-13-25(21-26)29(22-23-9-3-1-4-10-23)16-8-15-27-17-19-28(20-18-27)24-11-5-2-6-12-24/h1-7,9-14,21,30H,8,15-20,22H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	93	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis				Eur J Med Chem 80: 8-35 (2014) Article DOI: 10.1016/j.ejmech.2014.04.034 BindingDB Entry DOI: 10.7270/Q2HT2QV6
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50425479 (CHEMBL2313277) Show SMILES CC(=O)c1ccc(\C=C\c2cc3n(C)c(=O)n(C)c(=O)c3n2C)cc1 Show InChI InChI=1S/C19H19N3O3/c1-12(23)14-8-5-13(6-9-14)7-10-15-11-16-17(20(15)2)18(24)22(4)19(25)21(16)3/h5-11H,1-4H3/b10-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	94	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Parma Curated by ChEMBL					Assay Description Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HEK293 cells after 1 hr by microbeta scintillation counting analysis				J Med Chem 56: 1247-61 (2013) Article DOI: 10.1021/jm301686s BindingDB Entry DOI: 10.7270/Q2SB472H
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50015212 (CHEMBL3262433) Show SMILES Cl.CN(CCCCCCN1CCN(CC1)c1cccc(c1)C(F)(F)F)c1cccc(O)c1 Show InChI InChI=1S/C24H32F3N3O.ClH/c1-28(21-9-7-11-23(31)19-21)12-4-2-3-5-13-29-14-16-30(17-15-29)22-10-6-8-20(18-22)24(25,26)27;/h6-11,18-19,31H,2-5,12-17H2,1H3;1H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	96	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis				Eur J Med Chem 80: 8-35 (2014) Article DOI: 10.1016/j.ejmech.2014.04.034 BindingDB Entry DOI: 10.7270/Q2HT2QV6
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50176058 (2-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-...) Show SMILES CCCCc1nc(N)c2nc(-n3nccn3)n(C)c2n1 Show InChI InChI=1S/C12H16N8/c1-3-4-5-8-16-10(13)9-11(17-8)19(2)12(18-9)20-14-6-7-15-20/h6-7H,3-5H2,1-2H3,(H2,13,16,17)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX from human recombinant adenosine A1 receptor expressed in CHO-K1 cells after 60 mins				J Med Chem 56: 5456-63 (2013) Article DOI: 10.1021/jm400491x BindingDB Entry DOI: 10.7270/Q2R49TQK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50015032 (CHEMBL3262418) Show SMILES OCc1cccc(NCCCN2CCN(CC2)c2ccccc2)c1 Show InChI InChI=1S/C20H27N3O/c24-17-18-6-4-7-19(16-18)21-10-5-11-22-12-14-23(15-13-22)20-8-2-1-3-9-20/h1-4,6-9,16,21,24H,5,10-15,17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	109	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis				Eur J Med Chem 80: 8-35 (2014) Article DOI: 10.1016/j.ejmech.2014.04.034 BindingDB Entry DOI: 10.7270/Q2HT2QV6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50015023 (CHEMBL3262413) Show SMILES CN(CCCN1CCN(CC1)c1ccccc1)c1cccc(F)c1 Show InChI InChI=1S/C20H26FN3/c1-22(20-10-5-7-18(21)17-20)11-6-12-23-13-15-24(16-14-23)19-8-3-2-4-9-19/h2-5,7-10,17H,6,11-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	112	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Urbino Curated by ChEMBL					Assay Description Displacement of [3H]5-HT from human 5-HT7 receptor expressed in HEK293 cells after 30 mins by microbeta counting analysis				Eur J Med Chem 80: 8-35 (2014) Article DOI: 10.1016/j.ejmech.2014.04.034 BindingDB Entry DOI: 10.7270/Q2HT2QV6
					More data for this Ligand-Target Pair

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