BindingDB PrimarySearch

Found 25 hits with Last Name = 'sakamaki' and Initial = 'y'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Vitamin D3 receptor (Homo sapiens (Human))	BDBM50388528 (CHEMBL2058272) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	0.0290	n/a	n/a	n/a	n/a	n/a	n/a
Showa Pharmaceutical University Curated by ChEMBL					Assay Description Displacement of [3H]1alpha,25-dihydroxyvitamin D3 from human recombinant GST-tagged vitamin D3 receptor LBD expressed in Escherichia coli BL21 after ...				J Med Chem 55: 4373-81 (2012) Article DOI: 10.1021/jm300230a BindingDB Entry DOI: 10.7270/Q25M66R0
Showa Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Vitamin D3 receptor (Homo sapiens (Human))	BDBM50200182 ((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	0.0600	n/a	n/a	n/a	n/a	n/a	n/a
Showa Pharmaceutical University Curated by ChEMBL					Assay Description Displacement of [3H]-1alpha,25-dihydroxyvitamin D3 from recombinant human VDR LBD expressed in Escherichia coli BL21 (DE3) pLysS after 16 hrs				Bioorg Med Chem 23: 7274-81 (2015) Article DOI: 10.1016/j.bmc.2015.10.026 BindingDB Entry DOI: 10.7270/Q2R78H20
Showa Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Vitamin D3 receptor (Homo sapiens (Human))	BDBM50129805 (CHEMBL3629552) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
Showa Pharmaceutical University Curated by ChEMBL					Assay Description Displacement of [3H]-1alpha,25-dihydroxyvitamin D3 from recombinant human VDR LBD expressed in Escherichia coli BL21 (DE3) pLysS after 16 hrs				Bioorg Med Chem 23: 7274-81 (2015) Article DOI: 10.1016/j.bmc.2015.10.026 BindingDB Entry DOI: 10.7270/Q2R78H20
Showa Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Vitamin D3 receptor (Homo sapiens (Human))	BDBM50388529 (CHEMBL2058273) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.380	n/a	n/a	n/a	n/a	n/a	n/a
Showa Pharmaceutical University Curated by ChEMBL					Assay Description Displacement of [3H]1alpha,25-dihydroxyvitamin D3 from human recombinant GST-tagged vitamin D3 receptor LBD expressed in Escherichia coli BL21 after ...				J Med Chem 55: 4373-81 (2012) Article DOI: 10.1021/jm300230a BindingDB Entry DOI: 10.7270/Q25M66R0
Showa Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Vitamin D3 receptor (Homo sapiens (Human))	BDBM50388530 (CHEMBL2058274) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	0.410	n/a	n/a	n/a	n/a	n/a	n/a
Showa Pharmaceutical University Curated by ChEMBL					Assay Description Displacement of [3H]1alpha,25-dihydroxyvitamin D3 from human recombinant GST-tagged vitamin D3 receptor LBD expressed in Escherichia coli BL21 after ...				J Med Chem 55: 4373-81 (2012) Article DOI: 10.1021/jm300230a BindingDB Entry DOI: 10.7270/Q25M66R0
Showa Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase (Pseudomonas aeruginosa (PAO1))	BDBM159600 (US8772490, Example 23 \| US9035062, 23) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	650	n/a	n/a	n/a	n/a	7.0	30
Meiji Seika Pharma Co., Ltd. US Patent					Assay Description For the measurement of β-lactamase inhibitory activity, 100 uM (final concentration) nitrocefin (Oxoid) was used as a substrate, and 2.5% DMSO, ...				US Patent US8772490 (2014) BindingDB Entry DOI: 10.7270/Q2NK3CWQ
Meiji Seika Pharma Co., Ltd. US Patent					More data for this Ligand-Target Pair
Beta-lactamase (Pseudomonas aeruginosa (PAO1))	BDBM212440 (US8772490, H) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	650	n/a	n/a	n/a	n/a	7.0	30
Meiji Seika Pharma Co., Ltd. US Patent					Assay Description For the measurement of β-lactamase inhibitory activity, 100 uM (final concentration) nitrocefin (Oxoid) was used as a substrate, and 2.5% DMSO, ...				US Patent US8772490 (2014) BindingDB Entry DOI: 10.7270/Q2NK3CWQ
Meiji Seika Pharma Co., Ltd. US Patent					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM159600 (US8772490, Example 23 \| US9035062, 23) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	650	n/a	n/a	n/a	n/a	7.0	n/a
MEIJI SEIKA PHARMA CO., LTD. US Patent					Assay Description For the measurement of β-lactamase inhibitory activity, 100 μM (final concentration) nitrocefin (Oxoid) was used as a substrate, and 2.5% D...				US Patent US9035062 (2015) BindingDB Entry DOI: 10.7270/Q2KP80XX
MEIJI SEIKA PHARMA CO., LTD. US Patent					More data for this Ligand-Target Pair
Beta-lactamase (Pseudomonas aeruginosa (PAO1))	BDBM191563 (US9676777, example 23) Show SMILES NC(=O)[C@@H]1CC[C@@H]2CN1C(=O)N2O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	650	n/a	n/a	n/a	n/a	7.0	n/a
MEIJI SEIKA PHARMA CO., LTD. US Patent					Assay Description For the measurement of β-lactamase inhibitory activity, 100 μM (final concentration) nitrocefin (Oxoid) was used as a substrate, and 2.5% D...				US Patent US9676777 (2017) BindingDB Entry DOI: 10.7270/Q2G15Z17
MEIJI SEIKA PHARMA CO., LTD. US Patent					More data for this Ligand-Target Pair
Beta-lactamase (Pseudomonas aeruginosa (PAO1))	BDBM212441 (US8772490, TAZ) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	950	n/a	n/a	n/a	n/a	7.0	30
Meiji Seika Pharma Co., Ltd. US Patent					Assay Description For the measurement of β-lactamase inhibitory activity, 100 uM (final concentration) nitrocefin (Oxoid) was used as a substrate, and 2.5% DMSO, ...				US Patent US8772490 (2014) BindingDB Entry DOI: 10.7270/Q2NK3CWQ
Meiji Seika Pharma Co., Ltd. US Patent					More data for this Ligand-Target Pair
Beta-lactamase (Pseudomonas aeruginosa (PAO1))	BDBM50053173 ((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	950	n/a	n/a	n/a	n/a	7.0	n/a
MEIJI SEIKA PHARMA CO., LTD. US Patent					Assay Description For the measurement of β-lactamase inhibitory activity, 100 μM (final concentration) nitrocefin (Oxoid) was used as a substrate, and 2.5% D...				US Patent US9676777 (2017) BindingDB Entry DOI: 10.7270/Q2G15Z17
MEIJI SEIKA PHARMA CO., LTD. US Patent					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM50157692 (CHEMBL1439 \| CL-307579 \| Sodium; (2S,3S,5R)-3-meth...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	950	n/a	n/a	n/a	n/a	7.0	n/a
MEIJI SEIKA PHARMA CO., LTD. US Patent					Assay Description For the measurement of β-lactamase inhibitory activity, 100 μM (final concentration) nitrocefin (Oxoid) was used as a substrate, and 2.5% D...				US Patent US9035062 (2015) BindingDB Entry DOI: 10.7270/Q2KP80XX
MEIJI SEIKA PHARMA CO., LTD. US Patent					More data for this Ligand-Target Pair
Beta-lactamase (Pseudomonas aeruginosa (PAO1))	BDBM191564 (US9676777, example 24) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	7.0	n/a
MEIJI SEIKA PHARMA CO., LTD. US Patent					Assay Description For the measurement of β-lactamase inhibitory activity, 100 μM (final concentration) nitrocefin (Oxoid) was used as a substrate, and 2.5% D...				US Patent US9676777 (2017) BindingDB Entry DOI: 10.7270/Q2G15Z17
MEIJI SEIKA PHARMA CO., LTD. US Patent					More data for this Ligand-Target Pair
Beta-lactamase (Escherichia coli)	BDBM159601 (US8772490, Example 24 \| US9035062, 24) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	7.0	n/a
MEIJI SEIKA PHARMA CO., LTD. US Patent					Assay Description For the measurement of β-lactamase inhibitory activity, 100 μM (final concentration) nitrocefin (Oxoid) was used as a substrate, and 2.5% D...				US Patent US9035062 (2015) BindingDB Entry DOI: 10.7270/Q2KP80XX
MEIJI SEIKA PHARMA CO., LTD. US Patent					More data for this Ligand-Target Pair
Beta-lactamase (Pseudomonas aeruginosa (PAO1))	BDBM159601 (US8772490, Example 24 \| US9035062, 24) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	7.0	30
Meiji Seika Pharma Co., Ltd. US Patent					Assay Description For the measurement of β-lactamase inhibitory activity, 100 uM (final concentration) nitrocefin (Oxoid) was used as a substrate, and 2.5% DMSO, ...				US Patent US8772490 (2014) BindingDB Entry DOI: 10.7270/Q2NK3CWQ
Meiji Seika Pharma Co., Ltd. US Patent					More data for this Ligand-Target Pair
Beta-lactamase (Pseudomonas aeruginosa (PAO1))	BDBM159601 (US8772490, Example 24 \| US9035062, 24) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	7.0	30
Meiji Seika Pharma Co., Ltd. US Patent					Assay Description For the measurement of β-lactamase inhibitory activity, 100 uM (final concentration) nitrocefin (Oxoid) was used as a substrate, and 2.5% DMSO, ...				US Patent US8772490 (2014) BindingDB Entry DOI: 10.7270/Q2NK3CWQ
Meiji Seika Pharma Co., Ltd. US Patent					More data for this Ligand-Target Pair
Vitamin D3 receptor (Bos taurus)	BDBM50293099 ((1alpha,22S,24S)-22-Butyl-1,24-dihydroxyvitamin D3...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.80	n/a	n/a	n/a	n/a
Showa Pharmaceutical University Curated by ChEMBL					Assay Description Displacement of [3H]1,25-(OH)2D3 from bovine thymus vitamin D receptor				J Med Chem 52: 1438-49 (2010) Article DOI: 10.1021/jm8014348 BindingDB Entry DOI: 10.7270/Q2251J6N
Showa Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Vitamin D3 receptor (Bos taurus)	BDBM50293098 ((1R,3S,5Z)-5-[(2E)-2-{(1R,3aS,7aR)-1-[(1R,2S,4R)-2...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
Showa Pharmaceutical University Curated by ChEMBL					Assay Description Displacement of [3H]1,25-(OH)2D3 from bovine thymus vitamin D receptor				J Med Chem 52: 1438-49 (2010) Article DOI: 10.1021/jm8014348 BindingDB Entry DOI: 10.7270/Q2251J6N
Showa Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Vitamin D3 receptor (Bos taurus)	BDBM50293097 ((1alpha,22R,24S)-22-Butyl-1,24-dihydroxyvitamin D3...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.40	n/a	n/a	n/a	n/a
Showa Pharmaceutical University Curated by ChEMBL					Assay Description Displacement of [3H]1,25-(OH)2D3 from bovine thymus vitamin D receptor				J Med Chem 52: 1438-49 (2010) Article DOI: 10.1021/jm8014348 BindingDB Entry DOI: 10.7270/Q2251J6N
Showa Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Vitamin D3 receptor (Bos taurus)	BDBM50293096 ((1alpha,22R,24R)-22-Butyl-1,24-dihydroxyvitamin D3...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a
Showa Pharmaceutical University Curated by ChEMBL					Assay Description Displacement of [3H]1,25-(OH)2D3 from bovine thymus vitamin D receptor				J Med Chem 52: 1438-49 (2010) Article DOI: 10.1021/jm8014348 BindingDB Entry DOI: 10.7270/Q2251J6N
Showa Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Vitamin D3 receptor (Bos taurus)	BDBM50293095 (20S,22R-Butyl-1alpha,24-dihydroxy-24,25,26-trinorv...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
Showa Pharmaceutical University Curated by ChEMBL					Assay Description Displacement of [3H]1,25-(OH)2D3 from bovine thymus vitamin D receptor				J Med Chem 52: 1438-49 (2010) Article DOI: 10.1021/jm8014348 BindingDB Entry DOI: 10.7270/Q2251J6N
Showa Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Vitamin D3 receptor (Bos taurus)	BDBM50293094 ((1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2S,3S)-3-(2...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
Showa Pharmaceutical University Curated by ChEMBL					Assay Description Displacement of [3H]1,25-(OH)2D3 from bovine thymus vitamin D receptor				J Med Chem 52: 1438-49 (2010) Article DOI: 10.1021/jm8014348 BindingDB Entry DOI: 10.7270/Q2251J6N
Showa Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Vitamin D3 receptor (Bos taurus)	BDBM50293093 ((1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R,3S)-3-(2...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.20	n/a	n/a	n/a	n/a
Showa Pharmaceutical University Curated by ChEMBL					Assay Description Displacement of [3H]1,25-(OH)2D3 from bovine thymus vitamin D receptor				J Med Chem 52: 1438-49 (2010) Article DOI: 10.1021/jm8014348 BindingDB Entry DOI: 10.7270/Q2251J6N
Showa Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Vitamin D3 receptor (Bos taurus)	BDBM50293092 (22R-Butyl-1alpha,24-dihydroxy-24,25,26-trinorvitam...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
Showa Pharmaceutical University Curated by ChEMBL					Assay Description Displacement of [3H]1,25-(OH)2D3 from bovine thymus vitamin D receptor				J Med Chem 52: 1438-49 (2010) Article DOI: 10.1021/jm8014348 BindingDB Entry DOI: 10.7270/Q2251J6N
Showa Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair
Vitamin D3 receptor (Bos taurus)	BDBM50200182 ((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0500	n/a	n/a	n/a	n/a
Showa Pharmaceutical University Curated by ChEMBL					Assay Description Displacement of [3H]1,25-(OH)2D3 from bovine thymus vitamin D receptor				J Med Chem 52: 1438-49 (2010) Article DOI: 10.1021/jm8014348 BindingDB Entry DOI: 10.7270/Q2251J6N
Showa Pharmaceutical University Curated by ChEMBL					More data for this Ligand-Target Pair