| Reaction Details |
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 | Report a problem with these data |
| Target | Vitamin D3 receptor |
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| Ligand | BDBM50293096 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_514897 (CHEMBL972705) |
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| EC50 | 16±n/a nM |
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| Citation |  Inaba, Y; Yoshimoto, N; Sakamaki, Y; Nakabayashi, M; Ikura, T; Tamamura, H; Ito, N; Shimizu, M; Yamamoto, K A new class of vitamin D analogues that induce structural rearrangement of the ligand-binding pocket of the receptor. J Med Chem52:1438-49 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Vitamin D3 receptor |
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| Name: | Vitamin D3 receptor |
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| Synonyms: | NR1I1 | VDR | VDR_BOVIN | Vitamin D receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 48313.44 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_514897 |
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| Residue: | 426 |
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| Sequence: | MEATAASTSLPDPGDFDRNVPRICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTC
PFNGDCRITKDNRRHCQACRLKRCIDIGMMKEFILTDEEVQRKREMILKRKEEEALKDSL
RPKLSEEQQRIITTLLEAHHKTYDDTYSDFSQFRPPVRNSEDEGNRPLRSILTPSFSGNS
SSSCSDHCTSSPDTMEPTSFSNQDLNEEDSDDPSVTLDLSQLSMLPHLADLVSYSIQKVI
GFAKMIPGFRDLTPEDQIVLLKSSAIEVIMLRSNQSFTLDDDMSWTCGSPDYKYQVSDVT
RAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDRPGVQDAALVEAIQDRLSN
TLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQYRCLSFQPESSMKLTPLLFEV
FGNEIS
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| BDBM50293096 |
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| n/a |
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| Name | BDBM50293096 |
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| Synonyms: | (1alpha,22R,24R)-22-Butyl-1,24-dihydroxyvitamin D3 | CHEMBL507787 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H52O3 |
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| Mol. Mass. | 472.7428 |
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| SMILES | CCCC[C@H](C[C@@H](O)C(C)C)[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C |r| |
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| Structure | 
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