Compile Data Set for Download or QSAR

Found 679 hits with Last Name = 'shaver' and Initial = 'sr'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2Y purinoceptor 12 (Homo sapiens (Human))	BDBM50371580 (CHEMBL1162175) Show SMILES CCNC(=O)Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(O)=O)[C@H]2O[C@@H](O[C@@H]12)\C=C\c1ccccc1 |r| Show InChI InChI=1S/C22H25N6O8P/c1-2-23-22(29)27-19-16-20(25-11-24-19)28(12-26-16)21-18-17(14(34-21)10-33-37(30,31)32)35-15(36-18)9-8-13-6-4-3-5-7-13/h3-9,11-12,14-15,17-18,21H,2,10H2,1H3,(H2,30,31,32)(H2,23,24,25,27,29)/b9-8+/t14-,15+,17-,18-,21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Inspire Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Antagonist activity at P2Y12 receptor assessed as inhibition of ADP-induced human platelet aggregation by washed platelet assay				J Med Chem 51: 1007-25 (2008) Article DOI: 10.1021/jm701348d BindingDB Entry DOI: 10.7270/Q2P55PB6
					More data for this Ligand-Target Pair
P2Y purinoceptor 12 (Homo sapiens (Human))	BDBM50371581 (CHEMBL1162179) Show SMILES CCNC(=O)Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(O)=O)[C@H]2OC(O[C@@H]12)c1ccccc1 |r| Show InChI InChI=1S/C20H23N6O8P/c1-2-21-20(27)25-16-13-17(23-9-22-16)26(10-24-13)18-15-14(12(32-18)8-31-35(28,29)30)33-19(34-15)11-6-4-3-5-7-11/h3-7,9-10,12,14-15,18-19H,2,8H2,1H3,(H2,28,29,30)(H2,21,22,23,25,27)/t12-,14-,15-,18-,19?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Inspire Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Antagonist activity at P2Y12 receptor assessed as inhibition of ADP-induced human platelet aggregation by washed platelet assay				J Med Chem 51: 1007-25 (2008) Article DOI: 10.1021/jm701348d BindingDB Entry DOI: 10.7270/Q2P55PB6
					More data for this Ligand-Target Pair
P2Y purinoceptor 12 (Homo sapiens (Human))	BDBM50371580 (CHEMBL1162175) Show SMILES CCNC(=O)Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(O)=O)[C@H]2O[C@@H](O[C@@H]12)\C=C\c1ccccc1 |r| Show InChI InChI=1S/C22H25N6O8P/c1-2-23-22(29)27-19-16-20(25-11-24-19)28(12-26-16)21-18-17(14(34-21)10-33-37(30,31)32)35-15(36-18)9-8-13-6-4-3-5-7-13/h3-9,11-12,14-15,17-18,21H,2,10H2,1H3,(H2,30,31,32)(H2,23,24,25,27,29)/b9-8+/t14-,15+,17-,18-,21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Inspire Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Antagonist activity at P2Y12 receptor assessed as inhibition of ADP-induced human platelet aggregation by washed platelet assay				J Med Chem 51: 1007-25 (2008) Article DOI: 10.1021/jm701348d BindingDB Entry DOI: 10.7270/Q2P55PB6
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50181473 (4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)met...) Show SMILES CC[C@@H]([C@H](C)O)n1ncn(-c2ccc(cc2)N2CCN(CC2)c2ccc(OC[C@@H]3CO[C@](Cn4cncn4)(C3)c3ccc(F)cc3F)cc2)c1=O |r| Show InChI InChI=1S/C37H42F2N8O4/c1-3-35(26(2)48)47-36(49)46(25-42-47)31-7-5-29(6-8-31)43-14-16-44(17-15-43)30-9-11-32(12-10-30)50-20-27-19-37(51-21-27,22-45-24-40-23-41-45)33-13-4-28(38)18-34(33)39/h4-13,18,23-27,35,48H,3,14-17,19-22H2,1-2H3/t26-,27+,35-,37-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Viamet Pharmaceuticals Inc., Durham, NC 27703, USA. Electronic address: cyates@viamet.com. Curated by ChEMBL					Assay Description Inhibition of CYP11B2 in human hepatocyte microsomes using deoxycorticosteroid substrate by HPLC/MS/MS method				Bioorg Med Chem Lett 27: 3243-3248 (2017) Article DOI: 10.1016/j.bmcl.2017.06.037 BindingDB Entry DOI: 10.7270/Q29889G6
					More data for this Ligand-Target Pair
P2Y purinoceptor 12 (Homo sapiens (Human))	BDBM50371582 (CHEMBL1162182) Show SMILES OP(O)(=O)OC[C@H]1O[C@H]([C@@H]2OC(Cc3ccccc3)O[C@H]12)n1cnc2c(NC(=O)NC3CCCC3)ncnc12 |r| Show InChI InChI=1S/C24H29N6O8P/c31-24(28-15-8-4-5-9-15)29-21-18-22(26-12-25-21)30(13-27-18)23-20-19(16(36-23)11-35-39(32,33)34)37-17(38-20)10-14-6-2-1-3-7-14/h1-3,6-7,12-13,15-17,19-20,23H,4-5,8-11H2,(H2,32,33,34)(H2,25,26,28,29,31)/t16-,17?,19-,20-,23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36.2	n/a	n/a	n/a	n/a	n/a	n/a
Inspire Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Antagonist activity at P2Y12 receptor assessed as inhibition of ADP-induced human platelet aggregation by washed platelet assay				J Med Chem 51: 1007-25 (2008) Article DOI: 10.1021/jm701348d BindingDB Entry DOI: 10.7270/Q2P55PB6
					More data for this Ligand-Target Pair
P2Y purinoceptor 12 (Homo sapiens (Human))	BDBM50371583 (CHEMBL1162184) Show SMILES CCNC(=O)Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(O)=O)[C@H]2OC(Cc3ccccc3)O[C@@H]12 |r| Show InChI InChI=1S/C21H25N6O8P/c1-2-22-21(28)26-18-15-19(24-10-23-18)27(11-25-15)20-17-16(13(33-20)9-32-36(29,30)31)34-14(35-17)8-12-6-4-3-5-7-12/h3-7,10-11,13-14,16-17,20H,2,8-9H2,1H3,(H2,29,30,31)(H2,22,23,24,26,28)/t13-,14?,16-,17-,20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Inspire Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Antagonist activity at P2Y12 receptor assessed as inhibition of ADP-induced human platelet aggregation by washed platelet assay				J Med Chem 51: 1007-25 (2008) Article DOI: 10.1021/jm701348d BindingDB Entry DOI: 10.7270/Q2P55PB6
					More data for this Ligand-Target Pair
Steroid 17-alpha-hydroxylase/17,20 lyase (Homo sapiens (Human))	BDBM50181473 (4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)met...) Show SMILES CC[C@@H]([C@H](C)O)n1ncn(-c2ccc(cc2)N2CCN(CC2)c2ccc(OC[C@@H]3CO[C@](Cn4cncn4)(C3)c3ccc(F)cc3F)cc2)c1=O |r| Show InChI InChI=1S/C37H42F2N8O4/c1-3-35(26(2)48)47-36(49)46(25-42-47)31-7-5-29(6-8-31)43-14-16-44(17-15-43)30-9-11-32(12-10-30)50-20-27-19-37(51-21-27,22-45-24-40-23-41-45)33-13-4-28(38)18-34(33)39/h4-13,18,23-27,35,48H,3,14-17,19-22H2,1-2H3/t26-,27+,35-,37-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Viamet Pharmaceuticals Inc., Durham, NC 27703, USA. Electronic address: cyates@viamet.com. Curated by ChEMBL					Assay Description Inhibition of CYP17 lyase in human hepatocyte microsomes using 17a-hydroxypregnenolone substrate by HPLC/MS/MS method				Bioorg Med Chem Lett 27: 3243-3248 (2017) Article DOI: 10.1016/j.bmcl.2017.06.037 BindingDB Entry DOI: 10.7270/Q29889G6
					More data for this Ligand-Target Pair
P2Y purinoceptor 12 (Homo sapiens (Human))	BDBM50371589 (CHEMBL1162196) Show SMILES Nc1ccn([C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@@H]3O[C@@H]([C@H]4O[C@@H](Cc5ccccc5)O[C@@H]34)n3ccc(=O)[nH]c3=O)[C@H]3O[C@@H](Cc4ccccc4)O[C@@H]23)c(=O)n1 |r| Show InChI InChI=1S/C34H39N5O22P4/c35-23-11-13-38(33(41)36-23)31-29-27(55-25(57-29)15-19-7-3-1-4-8-19)21(53-31)17-51-62(43,44)59-64(47,48)61-65(49,50)60-63(45,46)52-18-22-28-30(32(54-22)39-14-12-24(40)37-34(39)42)58-26(56-28)16-20-9-5-2-6-10-20/h1-14,21-22,25-32H,15-18H2,(H,43,44)(H,45,46)(H,47,48)(H,49,50)(H2,35,36,41)(H,37,40,42)/t21-,22+,25-,26+,27-,28+,29-,30+,31-,32+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Inspire Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Antagonist activity at P2Y12 receptor assessed as inhibition of ADP-induced human platelet aggregation by washed platelet assay				J Med Chem 51: 1007-25 (2008) Article DOI: 10.1021/jm701348d BindingDB Entry DOI: 10.7270/Q2P55PB6
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM287636 (US10085984, Example 14 | US11040034, Ex. No. 14) Show SMILES Fc1ccc2nc(-c3cnnc4ccccc34)n(C3CC3)c2c1 Show InChI InChI=1S/C18H13FN4/c19-11-5-8-16-17(9-11)23(12-6-7-12)18(21-16)14-10-20-22-15-4-2-1-3-13(14)15/h1-5,8-10,12H,6-7H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM287637 (US10085984, Example 15 | US11040034, Ex. No. 15) Show SMILES Cc1cc(cnn1)-c1nc2ccc(F)cc2n1C1CC1 Show InChI InChI=1S/C15H13FN4/c1-9-6-10(8-17-19-9)15-18-13-5-2-11(16)7-14(13)20(15)12-3-4-12/h2,5-8,12H,3-4H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM287640 (US10085984, Example 18 | US11040034, Ex. No. 18) Show SMILES CC(C)NC(=O)CN1CCN(CC1)c1cc(cnn1)-c1nc2ccc(F)cc2n1C1CC1 Show InChI InChI=1S/C23H28FN7O/c1-15(2)26-22(32)14-29-7-9-30(10-8-29)21-11-16(13-25-28-21)23-27-19-6-3-17(24)12-20(19)31(23)18-4-5-18/h3,6,11-13,15,18H,4-5,7-10,14H2,1-2H3,(H,26,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM287641 (US10085984, Example 19 | US11040034, Ex. No. 19) Show SMILES Cc1cc(cnn1)-c1nc2cc(F)c(F)cc2n1C1CC1 Show InChI InChI=1S/C15H12F2N4/c1-8-4-9(7-18-20-8)15-19-13-5-11(16)12(17)6-14(13)21(15)10-2-3-10/h4-7,10H,2-3H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM287643 (US10085984, Example 21 | US11040034, Ex. No. 21) Show SMILES CNc1cc(cnn1)-c1nc2cc(F)c(F)cc2n1C1CC1 Show InChI InChI=1S/C15H13F2N5/c1-18-14-4-8(7-19-21-14)15-20-12-5-10(16)11(17)6-13(12)22(15)9-2-3-9/h4-7,9H,2-3H2,1H3,(H,18,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM287644 (US10085984, Example 22 | US11040034, Ex. No. 22) Show SMILES Fc1cc2nc(-c3cnnc(Cl)c3)n(C3CC3)c2cc1F Show InChI InChI=1S/C14H9ClF2N4/c15-13-3-7(6-18-20-13)14-19-11-4-9(16)10(17)5-12(11)21(14)8-1-2-8/h3-6,8H,1-2H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM287645 (US10085984, Example 23 | US11040034, Ex. No. 23) Show SMILES COc1cc(cnn1)-c1nc2cc(F)c(F)cc2n1C1CC1 Show InChI InChI=1S/C15H12F2N4O/c1-22-14-4-8(7-18-20-14)15-19-12-5-10(16)11(17)6-13(12)21(15)9-2-3-9/h4-7,9H,2-3H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM287646 (US10085984, Example 24 | US11040034, Ex. No. 24) Show SMILES CC(C)Oc1cc(cnn1)-c1nc2cc(F)c(F)cc2n1C1CC1 Show InChI InChI=1S/C17H16F2N4O/c1-9(2)24-16-5-10(8-20-22-16)17-21-14-6-12(18)13(19)7-15(14)23(17)11-3-4-11/h5-9,11H,3-4H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM287647 (US10085984, Example 25 | US11040034, Ex. No. 25) Show SMILES CN(C)c1cc(cnn1)-c1nc2cc(F)c(F)cc2n1C1CC1 Show InChI InChI=1S/C16H15F2N5/c1-22(2)15-5-9(8-19-21-15)16-20-13-6-11(17)12(18)7-14(13)23(16)10-3-4-10/h5-8,10H,3-4H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM287648 (US10085984, Example 26 | US11040034, Ex. No. 26) Show SMILES CCn1c(nc2ccc(F)cc12)-c1cnnc(C)c1 Show InChI InChI=1S/C14H13FN4/c1-3-19-13-7-11(15)4-5-12(13)17-14(19)10-6-9(2)18-16-8-10/h4-8H,3H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM287649 (US10085984, Example 27 | US11040034, Ex. No. 27) Show SMILES Fc1cc2nc(-c3cnnc(OCC(F)(F)F)c3)n(C3CC3)c2cc1F Show InChI InChI=1S/C16H11F5N4O/c17-10-4-12-13(5-11(10)18)25(9-1-2-9)15(23-12)8-3-14(24-22-6-8)26-7-16(19,20)21/h3-6,9H,1-2,7H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM287650 (US10085984, Example 28 | US11040034, Ex. No. 28) Show SMILES COCCNc1cc(cnn1)-c1nc2cc(F)c(F)cc2n1C1CC1 Show InChI InChI=1S/C17H17F2N5O/c1-25-5-4-20-16-6-10(9-21-23-16)17-22-14-7-12(18)13(19)8-15(14)24(17)11-2-3-11/h6-9,11H,2-5H2,1H3,(H,20,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM287651 (US10085984, Example 29 | US11040034, Ex. No. 29) Show SMILES COc1cc(cnn1)-c1nc2ccc(cc2n1C1CC1)C#N Show InChI InChI=1S/C16H13N5O/c1-22-15-7-11(9-18-20-15)16-19-13-5-2-10(8-17)6-14(13)21(16)12-3-4-12/h2,5-7,9,12H,3-4H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM287652 (US10085984, Example 30 | US11040034, Ex. No. 30) Show SMILES Cc1cc(cnn1)-c1cc2ccc(F)cc2n1C1CC1 Show InChI InChI=1S/C16H14FN3/c1-10-6-12(9-18-19-10)15-7-11-2-3-13(17)8-16(11)20(15)14-4-5-14/h2-3,6-9,14H,4-5H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM287653 (US10085984, Example 31 | US11040034, Ex. No. 31) Show SMILES CCS(=O)(=O)NCc1cc(cnn1)-c1nc2ccc(F)cc2n1C1CC1 Show InChI InChI=1S/C17H18FN5O2S/c1-2-26(24,25)20-10-13-7-11(9-19-22-13)17-21-15-6-3-12(18)8-16(15)23(17)14-4-5-14/h3,6-9,14,20H,2,4-5,10H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM287654 (US10085984, Example 32 | US11040034, Ex. No. 32) Show SMILES Fc1cc2nc(-c3cnnc(NCC(F)(F)F)c3)n(C3CC3)c2cc1F Show InChI InChI=1S/C16H12F5N5/c17-10-4-12-13(5-11(10)18)26(9-1-2-9)15(24-12)8-3-14(25-23-6-8)22-7-16(19,20)21/h3-6,9H,1-2,7H2,(H,22,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM287655 (US10085984, Example 33 | US11040034, Ex. No. 33) Show SMILES CCc1cc(cnn1)-c1nc2cc(F)c(F)cc2n1C1CC1 Show InChI InChI=1S/C16H14F2N4/c1-2-10-5-9(8-19-21-10)16-20-14-6-12(17)13(18)7-15(14)22(16)11-3-4-11/h5-8,11H,2-4H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM287656 (US10085984, Example 34 | US11040034, Ex. No. 34) Show SMILES Clc1cc(cnn1)-c1nc2ccc(cc2n1C1CC1)C#N Show InChI InChI=1S/C15H10ClN5/c16-14-6-10(8-18-20-14)15-19-12-4-1-9(7-17)5-13(12)21(15)11-2-3-11/h1,4-6,8,11H,2-3H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM287657 (US10085984, Example 35 | US11040034, Ex. No. 35) Show SMILES Cc1cc(cnn1)-c1nc2ccc(cc2n1C1CC1)C#N Show InChI InChI=1S/C16H13N5/c1-10-6-12(9-18-20-10)16-19-14-5-2-11(8-17)7-15(14)21(16)13-3-4-13/h2,5-7,9,13H,3-4H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM287658 (US10085984, Example 36 | US11040034, Ex. No. 36) Show SMILES CN1CCN(CC1)c1cc(cnn1)-c1nc2cc(F)c(F)cc2n1C1CC1 Show InChI InChI=1S/C19H20F2N6/c1-25-4-6-26(7-5-25)18-8-12(11-22-24-18)19-23-16-9-14(20)15(21)10-17(16)27(19)13-2-3-13/h8-11,13H,2-7H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM287659 (US10085984, Example 37 | US11040034, Ex. No. 37) Show SMILES CC(=O)N1CCN(CC1)c1cc(cnn1)-c1nc2cc(F)c(F)cc2n1C1CC1 Show InChI InChI=1S/C20H20F2N6O/c1-12(29)26-4-6-27(7-5-26)19-8-13(11-23-25-19)20-24-17-9-15(21)16(22)10-18(17)28(20)14-2-3-14/h8-11,14H,2-7H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM287660 (US10085984, Example 38 | US11040034, Ex. No. 38) Show SMILES CS(=O)(=O)N1CCN(CC1)c1cc(cnn1)-c1nc2cc(F)c(F)cc2n1C1CC1 Show InChI InChI=1S/C19H20F2N6O2S/c1-30(28,29)26-6-4-25(5-7-26)18-8-12(11-22-24-18)19-23-16-9-14(20)15(21)10-17(16)27(19)13-2-3-13/h8-11,13H,2-7H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM504360 (US11040034, Ex. No. 39) Show SMILES CB(O)N1CCN(CC1)c1cc(cnn1)-c1nc2cc(F)c(F)cc2n1C1CC1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM504360 (US11040034, Ex. No. 39) Show SMILES CB(O)N1CCN(CC1)c1cc(cnn1)-c1nc2cc(F)c(F)cc2n1C1CC1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM287662 (US10085984, Example 40 | US11040034, Ex. No. 40) Show SMILES CCn1c(nc2ccc(cc12)C#N)-c1cnnc(OC)c1 Show InChI InChI=1S/C15H13N5O/c1-3-20-13-6-10(8-16)4-5-12(13)18-15(20)11-7-14(21-2)19-17-9-11/h4-7,9H,3H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM287663 (US10085984, Example 41 | US11040034, Ex. No. 41) Show SMILES CCc1cc(cnn1)-c1nc2ccc(cc2n1CC)C#N Show InChI InChI=1S/C16H15N5/c1-3-13-8-12(10-18-20-13)16-19-14-6-5-11(9-17)7-15(14)21(16)4-2/h5-8,10H,3-4H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM287664 (US10085984, Example 42 | US11040034, Ex. No. 42) Show SMILES FC(F)c1cc(cnn1)-c1nc2cc(F)c(F)cc2n1C1CC1 Show InChI InChI=1S/C15H10F4N4/c16-9-4-11-13(5-10(9)17)23(8-1-2-8)15(21-11)7-3-12(14(18)19)22-20-6-7/h3-6,8,14H,1-2H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM287665 (US10085984, Example 43 | US11040034, Ex. No. 43) Show SMILES Fc1cc2nc(-c3cnnc(OC4CCC4)c3)n(C3CC3)c2cc1F Show InChI InChI=1S/C18H16F2N4O/c19-13-7-15-16(8-14(13)20)24(11-4-5-11)18(22-15)10-6-17(23-21-9-10)25-12-2-1-3-12/h6-9,11-12H,1-5H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM287666 (US10085984, Example 44 | US11040034, Ex. No. 44) Show SMILES Fc1cc2nc(-c3cnnc(c3)N3CCC(F)(F)CC3)n(C3CC3)c2cc1F Show InChI InChI=1S/C19H17F4N5/c20-13-8-15-16(9-14(13)21)28(12-1-2-12)18(25-15)11-7-17(26-24-10-11)27-5-3-19(22,23)4-6-27/h7-10,12H,1-6H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM287667 (US10085984, Example 45 | US11040034, Ex. No. 45) Show SMILES Cc1cc(cnn1)-c1nc2ccc(Cl)nc2n1C1CC1 Show InChI InChI=1S/C14H12ClN5/c1-8-6-9(7-16-19-8)13-17-11-4-5-12(15)18-14(11)20(13)10-2-3-10/h4-7,10H,2-3H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM287668 (US10085984, Example 46 | US11040034, Ex. No. 46) Show SMILES Fc1cc2nc(-c3cnnc(c3)N3CCC(F)(F)C3)n(C3CC3)c2cc1F Show InChI InChI=1S/C18H15F4N5/c19-12-6-14-15(7-13(12)20)27(11-1-2-11)17(24-14)10-5-16(25-23-8-10)26-4-3-18(21,22)9-26/h5-8,11H,1-4,9H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM287669 (US10085984, Example 47 | US11040034, Ex. No. 47) Show SMILES OC(c1cc(cnn1)-c1nc2cc(F)c(F)cc2n1C1CC1)C(F)(F)F Show InChI InChI=1S/C16H11F5N4O/c17-9-4-11-13(5-10(9)18)25(8-1-2-8)15(23-11)7-3-12(24-22-6-7)14(26)16(19,20)21/h3-6,8,14,26H,1-2H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM287671 (US10085984, Example 49 | US11040034, Ex. No. 49) Show SMILES Fc1ccc(cc1)-c1cc(cnn1)-c1nc2cc(F)c(F)cc2n1C1CC1 Show InChI InChI=1S/C20H13F3N4/c21-13-3-1-11(2-4-13)17-7-12(10-24-26-17)20-25-18-8-15(22)16(23)9-19(18)27(20)14-5-6-14/h1-4,7-10,14H,5-6H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM287673 (US10085984, Example 51 | US11040034, Ex. No. 51) Show SMILES CC(C)c1cc(cnn1)-c1nc2cc(F)c(F)cc2n1C1CC1 Show InChI InChI=1S/C17H16F2N4/c1-9(2)14-5-10(8-20-22-14)17-21-15-6-12(18)13(19)7-16(15)23(17)11-3-4-11/h5-9,11H,3-4H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM504374 (US11040034, Ex. No. 53) Show SMILES CC(Oc1cc(cnn1)-c1nc2cc(F)c(F)cc2n1C1CC1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM504375 (US11040034, Ex. No. 54) Show SMILES Cc1cc(cnn1)-c1nc2ccc(nc2n1C1CC1)C#N Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM287679 (US10085984, Example 57 | US11040034, Ex. No. 57) Show SMILES CC(F)(F)COc1cc(cnn1)-c1nc2cc(F)c(F)cc2n1C1CC1 Show InChI InChI=1S/C17H14F4N4O/c1-17(20,21)8-26-15-4-9(7-22-24-15)16-23-13-5-11(18)12(19)6-14(13)25(16)10-2-3-10/h4-7,10H,2-3,8H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM287680 (US10085984, Example 58 | US11040034, Ex. No. 58) Show SMILES CC(C)c1cnncc1-c1nc2cc(F)c(F)cc2n1C1CC1 Show InChI InChI=1S/C17H16F2N4/c1-9(2)11-7-20-21-8-12(11)17-22-15-5-13(18)14(19)6-16(15)23(17)10-3-4-10/h5-10H,3-4H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM287681 (US10085984, Example 59 | US11040034, Ex. No. 59) Show SMILES Fc1cc2nc(-c3cnnc(c3)C3CC3)n(C3CC3)c2cc1F Show InChI InChI=1S/C17H14F2N4/c18-12-6-15-16(7-13(12)19)23(11-3-4-11)17(21-15)10-5-14(9-1-2-9)22-20-8-10/h5-9,11H,1-4H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM287683 (US10085984, Example 61 | US11040034, Ex. No. 61) Show SMILES Cc1cc(F)ccc1-c1cc(cnn1)-c1nc2cc(F)c(F)cc2n1C1CC1 Show InChI InChI=1S/C21H15F3N4/c1-11-6-13(22)2-5-15(11)18-7-12(10-25-27-18)21-26-19-8-16(23)17(24)9-20(19)28(21)14-3-4-14/h2,5-10,14H,3-4H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM287684 (US10085984, Example 62 | US11040034, Ex. No. 62) Show SMILES Fc1ccc(c(F)c1)-c1cc(cnn1)-c1nc2cc(F)c(F)cc2n1C1CC1 Show InChI InChI=1S/C20H12F4N4/c21-11-1-4-13(14(22)6-11)17-5-10(9-25-27-17)20-26-18-7-15(23)16(24)8-19(18)28(20)12-2-3-12/h1,4-9,12H,2-3H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM287685 (US10085984, Example 63 | US11040034, Ex. No. 63) Show SMILES Fc1ccc(cc1F)-c1cc(cnn1)-c1nc2cc(F)c(F)cc2n1C1CC1 Show InChI InChI=1S/C20H12F4N4/c21-13-4-1-10(5-14(13)22)17-6-11(9-25-27-17)20-26-18-7-15(23)16(24)8-19(18)28(20)12-2-3-12/h1,4-9,12H,2-3H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Enzyme assays for inhibitor screening employed CYP11B2 and CYP11B1 enzyme enriched microsomes and were run at the Km of the respective substrates. Pr...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KRW
					More data for this Ligand-Target Pair

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