Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prothrombin (Homo sapiens (Human)) | BDBM50324477 (Benzylsulfonyl-D-cyclohexylalanyl-proline-(4-amidi...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 0.102 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human thrombin | J Med Chem 53: 5523-35 (2010) Article DOI: 10.1021/jm100183e BindingDB Entry DOI: 10.7270/Q25B02PD | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50324478 (Benzylsulfonyl-D-cyclohexylalanyl-proline-(2-amino...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 0.108 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human thrombin | J Med Chem 53: 5523-35 (2010) Article DOI: 10.1021/jm100183e BindingDB Entry DOI: 10.7270/Q25B02PD | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50324476 (Benzylsulfonyl-D-arginyl-proline-(2-aminomethyl-5-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human thrombin | J Med Chem 53: 5523-35 (2010) Article DOI: 10.1021/jm100183e BindingDB Entry DOI: 10.7270/Q25B02PD | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50324475 (Benzylsulfonyl-D-argininyl-proline-(4-amidinobenzy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 1.94 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human thrombin | J Med Chem 53: 5523-35 (2010) Article DOI: 10.1021/jm100183e BindingDB Entry DOI: 10.7270/Q25B02PD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human)) | BDBM50324475 (Benzylsulfonyl-D-argininyl-proline-(4-amidinobenzy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 55 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human recombinant matriptase catalytic domain expressed in HEK293 cells after 20 mins | J Med Chem 53: 5523-35 (2010) Article DOI: 10.1021/jm100183e BindingDB Entry DOI: 10.7270/Q25B02PD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane protease serine 6 (Homo sapiens (Human)) | BDBM50324475 (Benzylsulfonyl-D-argininyl-proline-(4-amidinobenzy...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human purified matriptase 2 catalytic domain expressed in HEK293 cells after 20 mins | J Med Chem 53: 5523-35 (2010) Article DOI: 10.1021/jm100183e BindingDB Entry DOI: 10.7270/Q25B02PD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane protease serine 6 (Homo sapiens (Human)) | BDBM50324475 (Benzylsulfonyl-D-argininyl-proline-(4-amidinobenzy...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human recombinant matriptase 2 expressed in HEK293 cells in conditioned medium after 20 mins | J Med Chem 53: 5523-35 (2010) Article DOI: 10.1021/jm100183e BindingDB Entry DOI: 10.7270/Q25B02PD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypsin (Homo sapiens (Human)) | BDBM50189306 (CHEMBL3594083) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 192 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human trypsin using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysis | Bioorg Med Chem Lett 26: 3741-5 (2016) Article DOI: 10.1016/j.bmcl.2016.05.071 BindingDB Entry DOI: 10.7270/Q29025QN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human)) | BDBM50324476 (Benzylsulfonyl-D-arginyl-proline-(2-aminomethyl-5-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 220 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human recombinant matriptase catalytic domain expressed in HEK293 cells after 20 mins | J Med Chem 53: 5523-35 (2010) Article DOI: 10.1021/jm100183e BindingDB Entry DOI: 10.7270/Q25B02PD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypsin (Homo sapiens (Human)) | BDBM50189311 (4,4''-(1,2-Phenylenebis(Methylene))Bis(Oxy)Dibenzi...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 221 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human trypsin using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysis | Bioorg Med Chem Lett 26: 3741-5 (2016) Article DOI: 10.1016/j.bmcl.2016.05.071 BindingDB Entry DOI: 10.7270/Q29025QN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypsin (Homo sapiens (Human)) | BDBM50189307 (CHEMBL3594082) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 244 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human trypsin using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysis | Bioorg Med Chem Lett 26: 3741-5 (2016) Article DOI: 10.1016/j.bmcl.2016.05.071 BindingDB Entry DOI: 10.7270/Q29025QN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50189311 (4,4''-(1,2-Phenylenebis(Methylene))Bis(Oxy)Dibenzi...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 279 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human thrombin using Cbz-Gly-Gly-Arg-AMC as substrate after 20 mins by fluorimetric analysis | Bioorg Med Chem Lett 26: 3741-5 (2016) Article DOI: 10.1016/j.bmcl.2016.05.071 BindingDB Entry DOI: 10.7270/Q29025QN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane protease serine 6 (Homo sapiens (Human)) | BDBM50324477 (Benzylsulfonyl-D-cyclohexylalanyl-proline-(4-amidi...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 290 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human recombinant matriptase 2 expressed in HEK293 cells in conditioned medium after 20 mins | J Med Chem 53: 5523-35 (2010) Article DOI: 10.1021/jm100183e BindingDB Entry DOI: 10.7270/Q25B02PD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypsin (Homo sapiens (Human)) | BDBM50189310 (4,4''-(1,4-Phenylenebis(Methylene))Bis(Oxy)Dibenzi...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 316 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human trypsin using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysis | Bioorg Med Chem Lett 26: 3741-5 (2016) Article DOI: 10.1016/j.bmcl.2016.05.071 BindingDB Entry DOI: 10.7270/Q29025QN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50189306 (CHEMBL3594083) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 317 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human thrombin using Cbz-Gly-Gly-Arg-AMC as substrate after 20 mins by fluorimetric analysis | Bioorg Med Chem Lett 26: 3741-5 (2016) Article DOI: 10.1016/j.bmcl.2016.05.071 BindingDB Entry DOI: 10.7270/Q29025QN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Bos taurus) | BDBM50189310 (4,4''-(1,4-Phenylenebis(Methylene))Bis(Oxy)Dibenzi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 327 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of bovine factor 10a using Boc-Ile-Glu-Gly-Arg-AMC as substrate after 20 mins by fluorimetric analysis | Bioorg Med Chem Lett 26: 3741-5 (2016) Article DOI: 10.1016/j.bmcl.2016.05.071 BindingDB Entry DOI: 10.7270/Q29025QN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Bos taurus) | BDBM50189307 (CHEMBL3594082) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 391 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of bovine factor 10a using Boc-Ile-Glu-Gly-Arg-AMC as substrate after 20 mins by fluorimetric analysis | Bioorg Med Chem Lett 26: 3741-5 (2016) Article DOI: 10.1016/j.bmcl.2016.05.071 BindingDB Entry DOI: 10.7270/Q29025QN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human)) | BDBM50189308 (CHEMBL269032) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 397 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human matriptase using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysis | Bioorg Med Chem Lett 26: 3741-5 (2016) Article DOI: 10.1016/j.bmcl.2016.05.071 BindingDB Entry DOI: 10.7270/Q29025QN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane protease serine 6 (Homo sapiens (Human)) | BDBM50324477 (Benzylsulfonyl-D-cyclohexylalanyl-proline-(4-amidi...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 460 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human purified matriptase 2 catalytic domain expressed in HEK293 cells after 20 mins | J Med Chem 53: 5523-35 (2010) Article DOI: 10.1021/jm100183e BindingDB Entry DOI: 10.7270/Q25B02PD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human)) | BDBM50189305 (CHEMBL3828410) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 492 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human matriptase using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysis | Bioorg Med Chem Lett 26: 3741-5 (2016) Article DOI: 10.1016/j.bmcl.2016.05.071 BindingDB Entry DOI: 10.7270/Q29025QN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50189307 (CHEMBL3594082) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 499 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human thrombin using Cbz-Gly-Gly-Arg-AMC as substrate after 20 mins by fluorimetric analysis | Bioorg Med Chem Lett 26: 3741-5 (2016) Article DOI: 10.1016/j.bmcl.2016.05.071 BindingDB Entry DOI: 10.7270/Q29025QN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypsin (Homo sapiens (Human)) | BDBM50189309 (CHEMBL9126) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 513 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human trypsin using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysis | Bioorg Med Chem Lett 26: 3741-5 (2016) Article DOI: 10.1016/j.bmcl.2016.05.071 BindingDB Entry DOI: 10.7270/Q29025QN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human)) | BDBM50189306 (CHEMBL3594083) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 526 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human matriptase using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysis | Bioorg Med Chem Lett 26: 3741-5 (2016) Article DOI: 10.1016/j.bmcl.2016.05.071 BindingDB Entry DOI: 10.7270/Q29025QN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50394250 (CHEMBL2159280) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 530 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human thrombin using fluorogenic Cbz-Gly-Gly-Arg-NH-Mec as substrate measured over 400 secs by spectrophotometry | Bioorg Med Chem 20: 6489-505 (2012) Article DOI: 10.1016/j.bmc.2012.08.042 BindingDB Entry DOI: 10.7270/Q2SB46VD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human)) | BDBM50189307 (CHEMBL3594082) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 558 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human matriptase using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysis | Bioorg Med Chem Lett 26: 3741-5 (2016) Article DOI: 10.1016/j.bmcl.2016.05.071 BindingDB Entry DOI: 10.7270/Q29025QN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human)) | BDBM50189309 (CHEMBL9126) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 719 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human matriptase using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysis | Bioorg Med Chem Lett 26: 3741-5 (2016) Article DOI: 10.1016/j.bmcl.2016.05.071 BindingDB Entry DOI: 10.7270/Q29025QN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human)) | BDBM50324477 (Benzylsulfonyl-D-cyclohexylalanyl-proline-(4-amidi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 770 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human recombinant matriptase catalytic domain expressed in HEK293 cells after 20 mins | J Med Chem 53: 5523-35 (2010) Article DOI: 10.1021/jm100183e BindingDB Entry DOI: 10.7270/Q25B02PD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human)) | BDBM50189310 (4,4''-(1,4-Phenylenebis(Methylene))Bis(Oxy)Dibenzi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 816 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human matriptase using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysis | Bioorg Med Chem Lett 26: 3741-5 (2016) Article DOI: 10.1016/j.bmcl.2016.05.071 BindingDB Entry DOI: 10.7270/Q29025QN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50394254 (CHEMBL2159276) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 930 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human thrombin using fluorogenic Cbz-Gly-Gly-Arg-NH-Mec as substrate measured over 400 secs by spectrophotometry | Bioorg Med Chem 20: 6489-505 (2012) Article DOI: 10.1016/j.bmc.2012.08.042 BindingDB Entry DOI: 10.7270/Q2SB46VD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane protease serine 6 (Homo sapiens (Human)) | BDBM50189309 (CHEMBL9126) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human matriptase-2 transfected in HEK cells using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysis | Bioorg Med Chem Lett 26: 3741-5 (2016) Article DOI: 10.1016/j.bmcl.2016.05.071 BindingDB Entry DOI: 10.7270/Q29025QN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50189310 (4,4''-(1,4-Phenylenebis(Methylene))Bis(Oxy)Dibenzi...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human thrombin using Cbz-Gly-Gly-Arg-AMC as substrate after 20 mins by fluorimetric analysis | Bioorg Med Chem Lett 26: 3741-5 (2016) Article DOI: 10.1016/j.bmcl.2016.05.071 BindingDB Entry DOI: 10.7270/Q29025QN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Bos taurus) | BDBM50189306 (CHEMBL3594083) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.29E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of bovine factor 10a using Boc-Ile-Glu-Gly-Arg-AMC as substrate after 20 mins by fluorimetric analysis | Bioorg Med Chem Lett 26: 3741-5 (2016) Article DOI: 10.1016/j.bmcl.2016.05.071 BindingDB Entry DOI: 10.7270/Q29025QN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypsin (Homo sapiens (Human)) | BDBM50189305 (CHEMBL3828410) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.42E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human trypsin using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysis | Bioorg Med Chem Lett 26: 3741-5 (2016) Article DOI: 10.1016/j.bmcl.2016.05.071 BindingDB Entry DOI: 10.7270/Q29025QN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane protease serine 6 (Homo sapiens (Human)) | BDBM50189306 (CHEMBL3594083) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.64E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human matriptase-2 transfected in HEK cells using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysis | Bioorg Med Chem Lett 26: 3741-5 (2016) Article DOI: 10.1016/j.bmcl.2016.05.071 BindingDB Entry DOI: 10.7270/Q29025QN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypsin (Homo sapiens (Human)) | BDBM50189308 (CHEMBL269032) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human trypsin using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysis | Bioorg Med Chem Lett 26: 3741-5 (2016) Article DOI: 10.1016/j.bmcl.2016.05.071 BindingDB Entry DOI: 10.7270/Q29025QN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human)) | BDBM50286441 ((S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylami...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human recombinant matriptase catalytic domain expressed in HEK293 cells after 20 mins | J Med Chem 53: 5523-35 (2010) Article DOI: 10.1021/jm100183e BindingDB Entry DOI: 10.7270/Q25B02PD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human)) | BDBM50324478 (Benzylsulfonyl-D-cyclohexylalanyl-proline-(2-amino...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human recombinant matriptase catalytic domain expressed in HEK293 cells after 20 mins | J Med Chem 53: 5523-35 (2010) Article DOI: 10.1021/jm100183e BindingDB Entry DOI: 10.7270/Q25B02PD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human)) | BDBM50189311 (4,4''-(1,2-Phenylenebis(Methylene))Bis(Oxy)Dibenzi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.28E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human matriptase using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysis | Bioorg Med Chem Lett 26: 3741-5 (2016) Article DOI: 10.1016/j.bmcl.2016.05.071 BindingDB Entry DOI: 10.7270/Q29025QN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50394252 (CHEMBL2159278) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human thrombin using fluorogenic Cbz-Gly-Gly-Arg-NH-Mec as substrate measured over 400 secs by spectrophotometry | Bioorg Med Chem 20: 6489-505 (2012) Article DOI: 10.1016/j.bmc.2012.08.042 BindingDB Entry DOI: 10.7270/Q2SB46VD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane protease serine 6 (Homo sapiens (Human)) | BDBM50286441 ((S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylami...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human recombinant matriptase 2 expressed in HEK293 cells in conditioned medium after 20 mins | J Med Chem 53: 5523-35 (2010) Article DOI: 10.1021/jm100183e BindingDB Entry DOI: 10.7270/Q25B02PD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Bos taurus (Bovine)) | BDBM50189310 (4,4''-(1,4-Phenylenebis(Methylene))Bis(Oxy)Dibenzi...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of bovine thrombin using BANA/BPVANA as substrate after 15 to 40 mins | Bioorg Med Chem Lett 26: 3741-5 (2016) Article DOI: 10.1016/j.bmcl.2016.05.071 BindingDB Entry DOI: 10.7270/Q29025QN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane protease serine 6 (Homo sapiens (Human)) | BDBM50189307 (CHEMBL3594082) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.68E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human matriptase-2 transfected in HEK cells using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysis | Bioorg Med Chem Lett 26: 3741-5 (2016) Article DOI: 10.1016/j.bmcl.2016.05.071 BindingDB Entry DOI: 10.7270/Q29025QN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50394293 (CHEMBL2159394) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human thrombin using fluorogenic Cbz-Gly-Gly-Arg-NH-Mec as substrate measured over 400 secs by spectrophotometry | Bioorg Med Chem 20: 6489-505 (2012) Article DOI: 10.1016/j.bmc.2012.08.042 BindingDB Entry DOI: 10.7270/Q2SB46VD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane protease serine 6 (Homo sapiens (Human)) | BDBM50286441 ((S)-2-((S)-2-Acetylamino-4-(S)-methyl-pentanoylami...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 4.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human purified matriptase 2 catalytic domain expressed in HEK293 cells after 20 mins | J Med Chem 53: 5523-35 (2010) Article DOI: 10.1021/jm100183e BindingDB Entry DOI: 10.7270/Q25B02PD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane protease serine 6 (Homo sapiens (Human)) | BDBM50189308 (CHEMBL269032) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.39E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human matriptase-2 transfected in HEK cells using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysis | Bioorg Med Chem Lett 26: 3741-5 (2016) Article DOI: 10.1016/j.bmcl.2016.05.071 BindingDB Entry DOI: 10.7270/Q29025QN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50394258 (CHEMBL2159272) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human thrombin using fluorogenic Cbz-Gly-Gly-Arg-NH-Mec as substrate measured over 400 secs by spectrophotometry | Bioorg Med Chem 20: 6489-505 (2012) Article DOI: 10.1016/j.bmc.2012.08.042 BindingDB Entry DOI: 10.7270/Q2SB46VD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane protease serine 6 (Homo sapiens (Human)) | BDBM50189311 (4,4''-(1,2-Phenylenebis(Methylene))Bis(Oxy)Dibenzi...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human matriptase-2 transfected in HEK cells using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysis | Bioorg Med Chem Lett 26: 3741-5 (2016) Article DOI: 10.1016/j.bmcl.2016.05.071 BindingDB Entry DOI: 10.7270/Q29025QN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50189308 (CHEMBL269032) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human thrombin using Cbz-Gly-Gly-Arg-AMC as substrate after 20 mins by fluorimetric analysis | Bioorg Med Chem Lett 26: 3741-5 (2016) Article DOI: 10.1016/j.bmcl.2016.05.071 BindingDB Entry DOI: 10.7270/Q29025QN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transmembrane protease serine 6 (Homo sapiens (Human)) | BDBM50189310 (4,4''-(1,4-Phenylenebis(Methylene))Bis(Oxy)Dibenzi...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human matriptase-2 transfected in HEK cells using Boc-Gln-Ala-Arg-AMC as substrate after 20 mins by fluorimetric analysis | Bioorg Med Chem Lett 26: 3741-5 (2016) Article DOI: 10.1016/j.bmcl.2016.05.071 BindingDB Entry DOI: 10.7270/Q29025QN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50394288 (CHEMBL2159282) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.82E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human thrombin using fluorogenic Cbz-Gly-Gly-Arg-NH-Mec as substrate measured over 400 secs by spectrophotometry | Bioorg Med Chem 20: 6489-505 (2012) Article DOI: 10.1016/j.bmc.2012.08.042 BindingDB Entry DOI: 10.7270/Q2SB46VD | |||||||||||
More data for this Ligand-Target Pair |
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