Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutamate receptor 3 (RAT) | BDBM50252103 ((2S,3S,4S)-2-CARBOXY-4-[(1Z,3E,5R)-5-CARBOXY-1-MET...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | PubMed | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University Curated by PDSP Ki Database | J Pharmacol Exp Ther 296: 650-8 (2001) BindingDB Entry DOI: 10.7270/Q2M0440C | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 3 (RAT) | BDBM50002369 ((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University Curated by PDSP Ki Database | J Pharmacol Exp Ther 296: 650-8 (2001) BindingDB Entry DOI: 10.7270/Q2M0440C | ||||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor 3 (RAT) | BDBM85740 (Dysiherbaine) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | MMDB PC cid PC sid PDB UniChem Patents | PubMed | 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University Curated by PDSP Ki Database | J Pharmacol Exp Ther 296: 650-8 (2001) BindingDB Entry DOI: 10.7270/Q2M0440C | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 3 (RAT) | BDBM17657 ((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 62 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University Curated by PDSP Ki Database | J Pharmacol Exp Ther 296: 650-8 (2001) BindingDB Entry DOI: 10.7270/Q2M0440C | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 3 (RAT) | BDBM17657 ((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 62 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University Curated by PDSP Ki Database | J Pharmacol Exp Ther 296: 650-8 (2001) BindingDB Entry DOI: 10.7270/Q2M0440C | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 3 (RAT) | BDBM17657 ((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 89 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University Curated by PDSP Ki Database | J Pharmacol Exp Ther 296: 650-8 (2001) BindingDB Entry DOI: 10.7270/Q2M0440C | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 3 (RAT) | BDBM85740 (Dysiherbaine) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | MMDB PC cid PC sid PDB UniChem Patents | PubMed | 153 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University Curated by PDSP Ki Database | J Pharmacol Exp Ther 296: 650-8 (2001) BindingDB Entry DOI: 10.7270/Q2M0440C | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 3 (RAT) | BDBM50252103 ((2S,3S,4S)-2-CARBOXY-4-[(1Z,3E,5R)-5-CARBOXY-1-MET...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | PubMed | 927 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University Curated by PDSP Ki Database | J Pharmacol Exp Ther 296: 650-8 (2001) BindingDB Entry DOI: 10.7270/Q2M0440C | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 3 (RAT) | BDBM50002343 (2-Methylamino-succinic acid | CHEMBL275325 | NMDA) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PubMed | 3.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University Curated by PDSP Ki Database | J Pharmacol Exp Ther 296: 650-8 (2001) BindingDB Entry DOI: 10.7270/Q2M0440C | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor 3 (RAT) | BDBM85740 (Dysiherbaine) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | MMDB PC cid PC sid PDB UniChem Patents | PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University Curated by PDSP Ki Database | J Pharmacol Exp Ther 296: 650-8 (2001) BindingDB Entry DOI: 10.7270/Q2M0440C | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50082319 ((R)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6G | Bioorg Med Chem Lett 9: 2999-3002 (1999) BindingDB Entry DOI: 10.7270/Q2D21Z3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50082324 ((S)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6G | Bioorg Med Chem Lett 9: 2999-3002 (1999) BindingDB Entry DOI: 10.7270/Q2D21Z3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50082323 (4-[4-(4-Fluoro-benzyl)-phenyl]-1-((E)-3-phenyl-all...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6G | Bioorg Med Chem Lett 9: 2999-3002 (1999) BindingDB Entry DOI: 10.7270/Q2D21Z3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50082319 ((R)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6G | Bioorg Med Chem Lett 9: 2999-3002 (1999) BindingDB Entry DOI: 10.7270/Q2D21Z3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50017702 (1-(bis(4-fluorophenyl)methyl)-4-cinnamylpiperazine...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 228 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibition of [3H]raclopride binding to Dopamine receptor D2 of rat striatum membranes | Bioorg Med Chem Lett 9: 2999-3002 (1999) BindingDB Entry DOI: 10.7270/Q2D21Z3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50017702 (1-(bis(4-fluorophenyl)methyl)-4-cinnamylpiperazine...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 228 | n/a | n/a | n/a | n/a | n/a | n/a |
Suntory Biomedical Research Limited Curated by ChEMBL | Assay Description Concentration required for 50% inhibitory effect on Dopamine receptor D2 determined in competition experiments with [3H]raclopride | J Med Chem 43: 3372-6 (2000) BindingDB Entry DOI: 10.7270/Q27945CD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50017702 (1-(bis(4-fluorophenyl)methyl)-4-cinnamylpiperazine...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 290 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6G | Bioorg Med Chem Lett 9: 2999-3002 (1999) BindingDB Entry DOI: 10.7270/Q2D21Z3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50082320 (4-(4-Phenoxy-phenyl)-1-((E)-3-phenyl-allyl)-piperi...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6G | Bioorg Med Chem Lett 9: 2999-3002 (1999) BindingDB Entry DOI: 10.7270/Q2D21Z3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50082322 (1-{4-[4-(4-Fluoro-benzyl)-phenyl]-piperidin-1-yl}-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 360 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6G | Bioorg Med Chem Lett 9: 2999-3002 (1999) BindingDB Entry DOI: 10.7270/Q2D21Z3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50091592 (7-{4-[Bis-(4-fluoro-phenyl)-methyl]-piperazin-1-yl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 1.69E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Suntory Biomedical Research Limited Curated by ChEMBL | Assay Description Concentration required for 50% inhibitory effect on Dopamine receptor D2 determined in competition experiments with [3H]raclopride | J Med Chem 43: 3372-6 (2000) BindingDB Entry DOI: 10.7270/Q27945CD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50082320 (4-(4-Phenoxy-phenyl)-1-((E)-3-phenyl-allyl)-piperi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 2.68E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibition of [3H]raclopride binding to Dopamine receptor D2 of rat striatum membranes | Bioorg Med Chem Lett 9: 2999-3002 (1999) BindingDB Entry DOI: 10.7270/Q2D21Z3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50082323 (4-[4-(4-Fluoro-benzyl)-phenyl]-1-((E)-3-phenyl-all...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 3.38E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibition of [3H]raclopride binding to Dopamine receptor D2 of rat striatum membranes | Bioorg Med Chem Lett 9: 2999-3002 (1999) BindingDB Entry DOI: 10.7270/Q2D21Z3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50082319 ((R)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4.08E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibition of [3H]raclopride binding to Dopamine receptor D2 of rat striatum membranes | Bioorg Med Chem Lett 9: 2999-3002 (1999) BindingDB Entry DOI: 10.7270/Q2D21Z3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50082324 ((S)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4.34E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibition of [3H]raclopride binding to Dopamine receptor D2 of rat striatum membranes | Bioorg Med Chem Lett 9: 2999-3002 (1999) BindingDB Entry DOI: 10.7270/Q2D21Z3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50082319 ((R)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4.64E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibition of [3H]raclopride binding to Dopamine receptor D2 of rat striatum membranes | Bioorg Med Chem Lett 9: 2999-3002 (1999) BindingDB Entry DOI: 10.7270/Q2D21Z3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50091591 ((2S)-1-(4-amino-2,3,5-trimethylphenoxy)-3-{4-[4-(4...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Suntory Biomedical Research Limited Curated by ChEMBL | Assay Description Concentration required for 50% inhibitory effect on Dopamine receptor D2 determined in competition experiments with [3H]raclopride | J Med Chem 43: 3372-6 (2000) BindingDB Entry DOI: 10.7270/Q27945CD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50082322 (1-{4-[4-(4-Fluoro-benzyl)-phenyl]-piperidin-1-yl}-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research Curated by ChEMBL | Assay Description Inhibition of [3H]raclopride binding to Dopamine receptor D2 of rat striatum membranes | Bioorg Med Chem Lett 9: 2999-3002 (1999) BindingDB Entry DOI: 10.7270/Q2D21Z3B | |||||||||||
More data for this Ligand-Target Pair |