Compile Data Set for Download or QSAR

Found 15 hits with Last Name = 'tukalo' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine--tRNA ligase, cytoplasmic (Saccharomyces cerevisiae S288c)	BDBM50370987 (TAVABOROLE) Show SMILES OB1OCc2cc(F)ccc12 Show InChI InChI=1S/C7H6BFO2/c9-6-1-2-7-5(3-6)4-11-8(7)10/h1-3,10H,4H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem	Article PubMed	1.85E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Anacor Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of Saccharomyces cerevisiae cytoplasmic leucyl-tRNA synthetase after 20 mins				Science 316: 1759-1761 (2007) Article DOI: 10.1126/science.1142189 BindingDB Entry DOI: 10.7270/Q2P84CQ2
					More data for this Ligand-Target Pair
Leucine--tRNA ligase, cytoplasmic (Saccharomyces cerevisiae S288c)	BDBM50370987 (TAVABOROLE) Show SMILES OB1OCc2cc(F)ccc12 Show InChI InChI=1S/C7H6BFO2/c9-6-1-2-7-5(3-6)4-11-8(7)10/h1-3,10H,4H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem	Article PubMed	3.14E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Anacor Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of Saccharomyces cerevisiae cytoplasmic leucyl-tRNA synthetase after 2 mins				Science 316: 1759-1761 (2007) Article DOI: 10.1126/science.1142189 BindingDB Entry DOI: 10.7270/Q2P84CQ2
					More data for this Ligand-Target Pair
Leucine--tRNA ligase, cytoplasmic (Saccharomyces cerevisiae S288c)	BDBM50370987 (TAVABOROLE) Show SMILES OB1OCc2cc(F)ccc12 Show InChI InChI=1S/C7H6BFO2/c9-6-1-2-7-5(3-6)4-11-8(7)10/h1-3,10H,4H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Anacor Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of Saccharomyces cerevisiae cytoplasmic leucyl-tRNA synthetase assessed as tRNA amino-acylation				Science 316: 1759-1761 (2007) Article DOI: 10.1126/science.1142189 BindingDB Entry DOI: 10.7270/Q2P84CQ2
					More data for this Ligand-Target Pair
Leucine--tRNA ligase, cytoplasmic (Homo sapiens (Human))	BDBM50145676 (CHEMBL3764310) Show SMILES Oc1c(Br)cc(\C=N\Nc2nc(cs2)-c2ccc(cc2)[N+]([O-])=O)cc1Br Show InChI InChI=1S/C16H10Br2N4O3S/c17-12-5-9(6-13(18)15(12)23)7-19-21-16-20-14(8-26-16)10-1-3-11(4-2-10)22(24)25/h1-8,23H,(H,20,21)/b19-7+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.87E+4	n/a	n/a	n/a	n/a	n/a	n/a
NAS of Ukraine Curated by ChEMBL					Assay Description Inhibition of human leucyl-tRNA synthetase assessed as reduction of [14C]-L-leucine ligation to tRNA incubated for 5 mins by scintillation counting m...				Bioorg Med Chem 24: 1023-31 (2016) Article DOI: 10.1016/j.bmc.2016.01.028 BindingDB Entry DOI: 10.7270/Q2RN39Q8
					More data for this Ligand-Target Pair
Leucine--tRNA ligase, cytoplasmic (Homo sapiens (Human))	BDBM50145675 (CHEMBL3764493) Show SMILES COc1cc(\C=N\Nc2nc(cs2)-c2ccc(Cl)cc2)cc(Br)c1O Show InChI InChI=1S/C17H13BrClN3O2S/c1-24-15-7-10(6-13(18)16(15)23)8-20-22-17-21-14(9-25-17)11-2-4-12(19)5-3-11/h2-9,23H,1H3,(H,21,22)/b20-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.76E+4	n/a	n/a	n/a	n/a	n/a	n/a
NAS of Ukraine Curated by ChEMBL					Assay Description Inhibition of human leucyl-tRNA synthetase assessed as reduction of [14C]-L-leucine ligation to tRNA incubated for 5 mins by scintillation counting m...				Bioorg Med Chem 24: 1023-31 (2016) Article DOI: 10.1016/j.bmc.2016.01.028 BindingDB Entry DOI: 10.7270/Q2RN39Q8
					More data for this Ligand-Target Pair
Leucine--tRNA ligase, cytoplasmic (Homo sapiens (Human))	BDBM50145677 (CHEMBL3765025) Show SMILES COc1cc(\C=N/Nc2nc(cs2)-c2ccc(cc2)[N+]([O-])=O)cc(c1O)[N+]([O-])=O Show InChI InChI=1S/C17H13N5O6S/c1-28-15-7-10(6-14(16(15)23)22(26)27)8-18-20-17-19-13(9-29-17)11-2-4-12(5-3-11)21(24)25/h2-9,23H,1H3,(H,19,20)/b18-8-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
NAS of Ukraine Curated by ChEMBL					Assay Description Inhibition of human leucyl-tRNA synthetase assessed as reduction of [14C]-L-leucine ligation to tRNA incubated for 5 mins by scintillation counting m...				Bioorg Med Chem 24: 1023-31 (2016) Article DOI: 10.1016/j.bmc.2016.01.028 BindingDB Entry DOI: 10.7270/Q2RN39Q8
					More data for this Ligand-Target Pair
Leucine--tRNA ligase, cytoplasmic (Saccharomyces cerevisiae S288c)	BDBM50370990 (CHEMBL214011) Show SMILES OB1OCCc2cc(F)ccc12 Show InChI InChI=1S/C8H8BFO2/c10-7-1-2-8-6(5-7)3-4-12-9(8)11/h1-2,5,11H,3-4H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Anacor Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of Saccharomyces cerevisiae cytoplasmic leucyl-tRNA synthetase assessed as tRNA amino-acylation				Science 316: 1759-1761 (2007) Article DOI: 10.1126/science.1142189 BindingDB Entry DOI: 10.7270/Q2P84CQ2
					More data for this Ligand-Target Pair
Leucine--tRNA ligase, cytoplasmic (Saccharomyces cerevisiae S288c)	BDBM50370991 (CHEMBL388368) Show SMILES COCc1cc(F)ccc1B(O)O Show InChI InChI=1S/C8H10BFO3/c1-13-5-6-4-7(10)2-3-8(6)9(11)12/h2-4,11-12H,5H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Anacor Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of Saccharomyces cerevisiae cytoplasmic leucyl-tRNA synthetase assessed as tRNA amino-acylation				Science 316: 1759-1761 (2007) Article DOI: 10.1126/science.1142189 BindingDB Entry DOI: 10.7270/Q2P84CQ2
					More data for this Ligand-Target Pair
Leucine--tRNA ligase, cytoplasmic (Saccharomyces cerevisiae S288c)	BDBM26128 ((4-fluorophenyl)boranediol | CHEMBL344890 | Phenyl...) Show SMILES OB(O)c1ccc(F)cc1 Show InChI InChI=1S/C6H6BFO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4,9-10H	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Anacor Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of Saccharomyces cerevisiae cytoplasmic leucyl-tRNA synthetase assessed as tRNA amino-acylation				Science 316: 1759-1761 (2007) Article DOI: 10.1126/science.1142189 BindingDB Entry DOI: 10.7270/Q2P84CQ2
					More data for this Ligand-Target Pair
Leucine--tRNA ligase, cytoplasmic (Saccharomyces cerevisiae S288c)	BDBM50370992 (CHEMBL226509) Show SMILES OC1OCc2cc(F)ccc12 |w:1.0| Show InChI InChI=1S/C8H7FO2/c9-6-1-2-7-5(3-6)4-11-8(7)10/h1-3,8,10H,4H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Anacor Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of Saccharomyces cerevisiae cytoplasmic leucyl-tRNA synthetase assessed as tRNA amino-acylation				Science 316: 1759-1761 (2007) Article DOI: 10.1126/science.1142189 BindingDB Entry DOI: 10.7270/Q2P84CQ2
					More data for this Ligand-Target Pair
Leucine--tRNA ligase, cytoplasmic (Saccharomyces cerevisiae S288c)	BDBM50370988 (CHEMBL225804) Show SMILES Cc1cc(F)ccc1B(O)O Show InChI InChI=1S/C7H8BFO2/c1-5-4-6(9)2-3-7(5)8(10)11/h2-4,10-11H,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Anacor Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of Saccharomyces cerevisiae cytoplasmic leucyl-tRNA synthetase assessed as tRNA amino-acylation				Science 316: 1759-1761 (2007) Article DOI: 10.1126/science.1142189 BindingDB Entry DOI: 10.7270/Q2P84CQ2
					More data for this Ligand-Target Pair
Leucine--tRNA ligase, cytoplasmic (Saccharomyces cerevisiae S288c)	BDBM50370989 (CHEMBL226398) Show SMILES Fc1ccc2C(=O)OCc2c1 Show InChI InChI=1S/C8H5FO2/c9-6-1-2-7-5(3-6)4-11-8(7)10/h1-3H,4H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Anacor Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of Saccharomyces cerevisiae cytoplasmic leucyl-tRNA synthetase assessed as tRNA amino-acylation				Science 316: 1759-1761 (2007) Article DOI: 10.1126/science.1142189 BindingDB Entry DOI: 10.7270/Q2P84CQ2
					More data for this Ligand-Target Pair
Leucine--tRNA ligase, cytoplasmic (Homo sapiens (Human))	BDBM50145678 (CHEMBL3763921) Show SMILES COc1cc(\C=N/Nc2nc(cs2)-c2ccc(Br)cc2)cc(c1O)[N+]([O-])=O Show InChI InChI=1S/C17H13BrN4O4S/c1-26-15-7-10(6-14(16(15)23)22(24)25)8-19-21-17-20-13(9-27-17)11-2-4-12(18)5-3-11/h2-9,23H,1H3,(H,20,21)/b19-8-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.16E+5	n/a	n/a	n/a	n/a	n/a	n/a
NAS of Ukraine Curated by ChEMBL					Assay Description Inhibition of human leucyl-tRNA synthetase assessed as reduction of [14C]-L-leucine ligation to tRNA incubated for 5 mins by scintillation counting m...				Bioorg Med Chem 24: 1023-31 (2016) Article DOI: 10.1016/j.bmc.2016.01.028 BindingDB Entry DOI: 10.7270/Q2RN39Q8
					More data for this Ligand-Target Pair
Leucine--tRNA ligase, cytoplasmic (Homo sapiens (Human))	BDBM50145674 (CHEMBL2436531) Show SMILES CCOC(=O)c1sc(N\N=C\c2ccc(O)c(OC)c2)nc1C Show InChI InChI=1S/C15H17N3O4S/c1-4-22-14(20)13-9(2)17-15(23-13)18-16-8-10-5-6-11(19)12(7-10)21-3/h5-8,19H,4H2,1-3H3,(H,17,18)/b16-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.16E+5	n/a	n/a	n/a	n/a	n/a	n/a
NAS of Ukraine Curated by ChEMBL					Assay Description Inhibition of human leucyl-tRNA synthetase assessed as reduction of [14C]-L-leucine ligation to tRNA incubated for 5 mins by scintillation counting m...				Bioorg Med Chem 24: 1023-31 (2016) Article DOI: 10.1016/j.bmc.2016.01.028 BindingDB Entry DOI: 10.7270/Q2RN39Q8
					More data for this Ligand-Target Pair
Leucine--tRNA ligase, cytoplasmic (Saccharomyces cerevisiae S288c)	BDBM50370987 (TAVABOROLE) Show SMILES OB1OCc2cc(F)ccc12 Show InChI InChI=1S/C7H6BFO2/c9-6-1-2-7-5(3-6)4-11-8(7)10/h1-3,10H,4H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	2.08E+4	n/a	n/a	n/a	n/a	n/a
Anacor Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Binding affinity to Saccharomyces cerevisiae cytoplasmic leucyl-tRNA synthetase in presence of AMP				Science 316: 1759-1761 (2007) Article DOI: 10.1126/science.1142189 BindingDB Entry DOI: 10.7270/Q2P84CQ2
					More data for this Ligand-Target Pair