Compile Data Set for Download or QSAR

Found 32 hits with Last Name = 'welzel' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM28404 ((2E)-3-{3-[6-(1,4-diazepan-1-yl)pyrazin-2-yl]pheny...) Show SMILES OC(=O)\C=C\c1cccc(c1)-c1cncc(n1)N1CCCNCC1 Show InChI InChI=1S/C18H20N4O2/c23-18(24)6-5-14-3-1-4-15(11-14)16-12-20-13-17(21-16)22-9-2-7-19-8-10-22/h1,3-6,11-13,19H,2,7-10H2,(H,23,24)/b6-5+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	7.5	22
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...				J Med Chem 52: 1814-27 (2009) Article DOI: 10.1021/jm801242y BindingDB Entry DOI: 10.7270/Q25T3HS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM28397 ((2E)-3-(3-{6-[(4-aminocyclohexyl)amino]pyrazin-2-y...) Show SMILES N[C@H]1CC[C@@H](CC1)Nc1cncc(n1)-c1cccc(\C=C\C(O)=O)c1 |r,wU:4.7,wD:1.0,(-2.78,-3.68,;-2.78,-2.14,;-1.45,-1.37,;-1.45,.17,;-2.78,.94,;-4.12,.17,;-4.12,-1.37,;-2.78,2.48,;-1.45,3.25,;-1.45,4.8,;-.12,5.57,;1.22,4.8,;1.22,3.25,;-.12,2.48,;2.55,2.48,;3.88,3.26,;5.22,2.48,;5.22,.94,;3.88,.17,;3.88,-1.37,;5.22,-2.14,;5.22,-3.68,;6.55,-4.45,;3.88,-4.45,;2.55,.94,)| Show InChI InChI=1S/C19H22N4O2/c20-15-5-7-16(8-6-15)22-18-12-21-11-17(23-18)14-3-1-2-13(10-14)4-9-19(24)25/h1-4,9-12,15-16H,5-8,20H2,(H,22,23)(H,24,25)/b9-4+/t15-,16-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...				J Med Chem 52: 1814-27 (2009) Article DOI: 10.1021/jm801242y BindingDB Entry DOI: 10.7270/Q25T3HS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM28397 ((2E)-3-(3-{6-[(4-aminocyclohexyl)amino]pyrazin-2-y...) Show SMILES N[C@H]1CC[C@@H](CC1)Nc1cncc(n1)-c1cccc(\C=C\C(O)=O)c1 |r,wU:4.7,wD:1.0,(-2.78,-3.68,;-2.78,-2.14,;-1.45,-1.37,;-1.45,.17,;-2.78,.94,;-4.12,.17,;-4.12,-1.37,;-2.78,2.48,;-1.45,3.25,;-1.45,4.8,;-.12,5.57,;1.22,4.8,;1.22,3.25,;-.12,2.48,;2.55,2.48,;3.88,3.26,;5.22,2.48,;5.22,.94,;3.88,.17,;3.88,-1.37,;5.22,-2.14,;5.22,-3.68,;6.55,-4.45,;3.88,-4.45,;2.55,.94,)| Show InChI InChI=1S/C19H22N4O2/c20-15-5-7-16(8-6-15)22-18-12-21-11-17(23-18)14-3-1-2-13(10-14)4-9-19(24)25/h1-4,9-12,15-16H,5-8,20H2,(H,22,23)(H,24,25)/b9-4+/t15-,16-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	7.5	22
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...				J Med Chem 52: 1814-27 (2009) Article DOI: 10.1021/jm801242y BindingDB Entry DOI: 10.7270/Q25T3HS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM28417 ((2E)-3-(3-{6-[4-(aminomethyl)piperidin-1-yl]pyrazi...) Show SMILES NCC1CCN(CC1)c1cncc(n1)-c1cccc(\C=C\C(O)=O)c1 Show InChI InChI=1S/C19H22N4O2/c20-11-15-6-8-23(9-7-15)18-13-21-12-17(22-18)16-3-1-2-14(10-16)4-5-19(24)25/h1-5,10,12-13,15H,6-9,11,20H2,(H,24,25)/b5-4+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...				J Med Chem 52: 1814-27 (2009) Article DOI: 10.1021/jm801242y BindingDB Entry DOI: 10.7270/Q25T3HS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM28418 ((2E)-3-(3-{6-[(4-aminocyclohexyl)amino]pyrazin-2-y...) Show SMILES N[C@H]1CC[C@H](CC1)Nc1cncc(n1)-c1cccc(\C=C\C(O)=O)c1 |r,wD:4.7,1.0,(-2.78,-3.68,;-2.78,-2.14,;-1.45,-1.37,;-1.45,.17,;-2.78,.94,;-4.12,.17,;-4.12,-1.37,;-2.78,2.48,;-1.45,3.25,;-1.45,4.8,;-.12,5.57,;1.22,4.8,;1.22,3.25,;-.12,2.48,;2.55,2.48,;3.88,3.26,;5.22,2.48,;5.22,.94,;3.88,.17,;3.88,-1.37,;5.22,-2.14,;5.22,-3.68,;6.55,-4.45,;3.88,-4.45,;2.55,.94,)| Show InChI InChI=1S/C19H22N4O2/c20-15-5-7-16(8-6-15)22-18-12-21-11-17(23-18)14-3-1-2-13(10-14)4-9-19(24)25/h1-4,9-12,15-16H,5-8,20H2,(H,22,23)(H,24,25)/b9-4+/t15-,16+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...				J Med Chem 52: 1814-27 (2009) Article DOI: 10.1021/jm801242y BindingDB Entry DOI: 10.7270/Q25T3HS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM28395 ((2E)-3-(3-{6-[(4-aminobutyl)amino]pyrazin-2-yl}phe...) Show SMILES NCCCCNc1cncc(n1)-c1cccc(\C=C\C(O)=O)c1 Show InChI InChI=1S/C17H20N4O2/c18-8-1-2-9-20-16-12-19-11-15(21-16)14-5-3-4-13(10-14)6-7-17(22)23/h3-7,10-12H,1-2,8-9,18H2,(H,20,21)(H,22,23)/b7-6+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	7.5	22
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...				J Med Chem 52: 1814-27 (2009) Article DOI: 10.1021/jm801242y BindingDB Entry DOI: 10.7270/Q25T3HS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM28416 ((2E)-3-(3-{6-[(piperidin-4-ylmethyl)amino]pyrazin-...) Show SMILES OC(=O)\C=C\c1cccc(c1)-c1cncc(NCC2CCNCC2)n1 Show InChI InChI=1S/C19H22N4O2/c24-19(25)5-4-14-2-1-3-16(10-14)17-12-21-13-18(23-17)22-11-15-6-8-20-9-7-15/h1-5,10,12-13,15,20H,6-9,11H2,(H,22,23)(H,24,25)/b5-4+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...				J Med Chem 52: 1814-27 (2009) Article DOI: 10.1021/jm801242y BindingDB Entry DOI: 10.7270/Q25T3HS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM28411 ((2E)-3-(3-{6-[(3-aminopropyl)amino]pyrazin-2-yl}ph...) Show SMILES NCCCNc1cncc(n1)-c1cccc(\C=C\C(O)=O)c1 Show InChI InChI=1S/C16H18N4O2/c17-7-2-8-19-15-11-18-10-14(20-15)13-4-1-3-12(9-13)5-6-16(21)22/h1,3-6,9-11H,2,7-8,17H2,(H,19,20)(H,21,22)/b6-5+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	7.5	22
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...				J Med Chem 52: 1814-27 (2009) Article DOI: 10.1021/jm801242y BindingDB Entry DOI: 10.7270/Q25T3HS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM28395 ((2E)-3-(3-{6-[(4-aminobutyl)amino]pyrazin-2-yl}phe...) Show SMILES NCCCCNc1cncc(n1)-c1cccc(\C=C\C(O)=O)c1 Show InChI InChI=1S/C17H20N4O2/c18-8-1-2-9-20-16-12-19-11-15(21-16)14-5-3-4-13(10-14)6-7-17(22)23/h3-7,10-12H,1-2,8-9,18H2,(H,20,21)(H,22,23)/b7-6+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	7.5	22
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...				J Med Chem 52: 1814-27 (2009) Article DOI: 10.1021/jm801242y BindingDB Entry DOI: 10.7270/Q25T3HS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM28394 ((2E)-3-{3-[6-(4-methyl-1,4-diazepan-1-yl)pyrazin-2...) Show SMILES CN1CCCN(CC1)c1cncc(n1)-c1cccc(\C=C\C(O)=O)c1 Show InChI InChI=1S/C19H22N4O2/c1-22-8-3-9-23(11-10-22)18-14-20-13-17(21-18)16-5-2-4-15(12-16)6-7-19(24)25/h2,4-7,12-14H,3,8-11H2,1H3,(H,24,25)/b7-6+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	7.5	22
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...				J Med Chem 52: 1814-27 (2009) Article DOI: 10.1021/jm801242y BindingDB Entry DOI: 10.7270/Q25T3HS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM28398 ((2E)-3-{3-[6-(4-methyl-1,4-diazepan-1-yl)pyridin-2...) Show SMILES CN1CCCN(CC1)c1cccc(n1)-c1cccc(\C=C\C(O)=O)c1 Show InChI InChI=1S/C20H23N3O2/c1-22-11-4-12-23(14-13-22)19-8-3-7-18(21-19)17-6-2-5-16(15-17)9-10-20(24)25/h2-3,5-10,15H,4,11-14H2,1H3,(H,24,25)/b10-9+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...				J Med Chem 52: 1814-27 (2009) Article DOI: 10.1021/jm801242y BindingDB Entry DOI: 10.7270/Q25T3HS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM28398 ((2E)-3-{3-[6-(4-methyl-1,4-diazepan-1-yl)pyridin-2...) Show SMILES CN1CCCN(CC1)c1cccc(n1)-c1cccc(\C=C\C(O)=O)c1 Show InChI InChI=1S/C20H23N3O2/c1-22-11-4-12-23(14-13-22)19-8-3-7-18(21-19)17-6-2-5-16(15-17)9-10-20(24)25/h2-3,5-10,15H,4,11-14H2,1H3,(H,24,25)/b10-9+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	7.5	22
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...				J Med Chem 52: 1814-27 (2009) Article DOI: 10.1021/jm801242y BindingDB Entry DOI: 10.7270/Q25T3HS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM28394 ((2E)-3-{3-[6-(4-methyl-1,4-diazepan-1-yl)pyrazin-2...) Show SMILES CN1CCCN(CC1)c1cncc(n1)-c1cccc(\C=C\C(O)=O)c1 Show InChI InChI=1S/C19H22N4O2/c1-22-8-3-9-23(11-10-22)18-14-20-13-17(21-18)16-5-2-4-15(12-16)6-7-19(24)25/h2,4-7,12-14H,3,8-11H2,1H3,(H,24,25)/b7-6+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	7.5	22
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...				J Med Chem 52: 1814-27 (2009) Article DOI: 10.1021/jm801242y BindingDB Entry DOI: 10.7270/Q25T3HS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM28412 ((2E)-3-[3-(6-{[3-(dimethylamino)propyl]amino}pyraz...) Show SMILES CN(C)CCCNc1cncc(n1)-c1cccc(\C=C\C(O)=O)c1 Show InChI InChI=1S/C18H22N4O2/c1-22(2)10-4-9-20-17-13-19-12-16(21-17)15-6-3-5-14(11-15)7-8-18(23)24/h3,5-8,11-13H,4,9-10H2,1-2H3,(H,20,21)(H,23,24)/b8-7+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	94	n/a	n/a	n/a	n/a	7.5	22
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...				J Med Chem 52: 1814-27 (2009) Article DOI: 10.1021/jm801242y BindingDB Entry DOI: 10.7270/Q25T3HS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM28410 ((2E)-3-(3-{6-[(2-aminoethyl)amino]pyrazin-2-yl}phe...) Show SMILES NCCNc1cncc(n1)-c1cccc(\C=C\C(O)=O)c1 Show InChI InChI=1S/C15H16N4O2/c16-6-7-18-14-10-17-9-13(19-14)12-3-1-2-11(8-12)4-5-15(20)21/h1-5,8-10H,6-7,16H2,(H,18,19)(H,20,21)/b5-4+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	7.5	22
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...				J Med Chem 52: 1814-27 (2009) Article DOI: 10.1021/jm801242y BindingDB Entry DOI: 10.7270/Q25T3HS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM28407 ((2E)-3-{3-[6-(4-methylpiperazin-1-yl)pyrazin-2-yl]...) Show SMILES CN1CCN(CC1)c1cncc(n1)-c1cccc(\C=C\C(O)=O)c1 Show InChI InChI=1S/C18H20N4O2/c1-21-7-9-22(10-8-21)17-13-19-12-16(20-17)15-4-2-3-14(11-15)5-6-18(23)24/h2-6,11-13H,7-10H2,1H3,(H,23,24)/b6-5+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	7.5	22
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...				J Med Chem 52: 1814-27 (2009) Article DOI: 10.1021/jm801242y BindingDB Entry DOI: 10.7270/Q25T3HS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM28402 (1-methyl-4-(6-{3-[(E)-2-(1H-1,2,3,4-tetrazol-5-yl)...) Show SMILES CN1CCCN(CC1)c1cncc(n1)-c1cccc(C=Cc2nnn[nH]2)c1 |w:19.20| Show InChI InChI=1S/C19H22N8/c1-26-8-3-9-27(11-10-26)19-14-20-13-17(21-19)16-5-2-4-15(12-16)6-7-18-22-24-25-23-18/h2,4-7,12-14H,3,8-11H2,1H3,(H,22,23,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	7.5	22
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...				J Med Chem 52: 1814-27 (2009) Article DOI: 10.1021/jm801242y BindingDB Entry DOI: 10.7270/Q25T3HS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM28408 ((2E)-3-{3-[6-(piperazin-1-yl)pyrazin-2-yl]phenyl}p...) Show SMILES OC(=O)\C=C\c1cccc(c1)-c1cncc(n1)N1CCNCC1 Show InChI InChI=1S/C17H18N4O2/c22-17(23)5-4-13-2-1-3-14(10-13)15-11-19-12-16(20-15)21-8-6-18-7-9-21/h1-5,10-12,18H,6-9H2,(H,22,23)/b5-4+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	7.5	22
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...				J Med Chem 52: 1814-27 (2009) Article DOI: 10.1021/jm801242y BindingDB Entry DOI: 10.7270/Q25T3HS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM28419 ((2E)-3-(3-{6-[(4-hydroxycyclohexyl)amino]pyrazin-2...) Show SMILES O[C@H]1CC[C@@H](CC1)Nc1cncc(n1)-c1cccc(\C=C\C(O)=O)c1 |r,wU:4.7,wD:1.0,(-2.78,-3.68,;-2.78,-2.14,;-1.45,-1.37,;-1.45,.17,;-2.78,.94,;-4.12,.17,;-4.12,-1.37,;-2.78,2.48,;-1.45,3.25,;-1.45,4.8,;-.12,5.57,;1.22,4.8,;1.22,3.25,;-.12,2.48,;2.55,2.48,;3.88,3.26,;5.22,2.48,;5.22,.94,;3.88,.17,;3.88,-1.37,;5.22,-2.14,;5.22,-3.68,;6.55,-4.45,;3.88,-4.45,;2.55,.94,)| Show InChI InChI=1S/C19H21N3O3/c23-16-7-5-15(6-8-16)21-18-12-20-11-17(22-18)14-3-1-2-13(10-14)4-9-19(24)25/h1-4,9-12,15-16,23H,5-8H2,(H,21,22)(H,24,25)/b9-4+/t15-,16-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	265	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...				J Med Chem 52: 1814-27 (2009) Article DOI: 10.1021/jm801242y BindingDB Entry DOI: 10.7270/Q25T3HS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM28415 ((2E)-3-(3-{6-[(3-hydroxypropyl)amino]pyrazin-2-yl}...) Show SMILES OCCCNc1cncc(n1)-c1cccc(\C=C\C(O)=O)c1 Show InChI InChI=1S/C16H17N3O3/c20-8-2-7-18-15-11-17-10-14(19-15)13-4-1-3-12(9-13)5-6-16(21)22/h1,3-6,9-11,20H,2,7-8H2,(H,18,19)(H,21,22)/b6-5+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	7.5	22
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...				J Med Chem 52: 1814-27 (2009) Article DOI: 10.1021/jm801242y BindingDB Entry DOI: 10.7270/Q25T3HS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM28396 ((2E)-3-(3-{6-[(3-methoxypropyl)amino]pyrazin-2-yl}...) Show SMILES COCCCNc1cncc(n1)-c1cccc(\C=C\C(O)=O)c1 Show InChI InChI=1S/C17H19N3O3/c1-23-9-3-8-19-16-12-18-11-15(20-16)14-5-2-4-13(10-14)6-7-17(21)22/h2,4-7,10-12H,3,8-9H2,1H3,(H,19,20)(H,21,22)/b7-6+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	7.5	22
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...				J Med Chem 52: 1814-27 (2009) Article DOI: 10.1021/jm801242y BindingDB Entry DOI: 10.7270/Q25T3HS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM28413 ((2E)-3-[3-(6-{[3-(dimethylamino)propyl](methyl)ami...) Show SMILES CN(C)CCCN(C)c1cncc(n1)-c1cccc(\C=C\C(O)=O)c1 Show InChI InChI=1S/C19H24N4O2/c1-22(2)10-5-11-23(3)18-14-20-13-17(21-18)16-7-4-6-15(12-16)8-9-19(24)25/h4,6-9,12-14H,5,10-11H2,1-3H3,(H,24,25)/b9-8+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	7.5	22
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...				J Med Chem 52: 1814-27 (2009) Article DOI: 10.1021/jm801242y BindingDB Entry DOI: 10.7270/Q25T3HS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM28396 ((2E)-3-(3-{6-[(3-methoxypropyl)amino]pyrazin-2-yl}...) Show SMILES COCCCNc1cncc(n1)-c1cccc(\C=C\C(O)=O)c1 Show InChI InChI=1S/C17H19N3O3/c1-23-9-3-8-19-16-12-18-11-15(20-16)14-5-2-4-13(10-14)6-7-17(21)22/h2,4-7,10-12H,3,8-9H2,1H3,(H,19,20)(H,21,22)/b7-6+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	7.5	22
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...				J Med Chem 52: 1814-27 (2009) Article DOI: 10.1021/jm801242y BindingDB Entry DOI: 10.7270/Q25T3HS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM28406 ((2E)-3-{3-[6-(4-acetyl-1,4-diazepan-1-yl)pyrazin-2...) Show SMILES CC(=O)N1CCCN(CC1)c1cncc(n1)-c1cccc(\C=C\C(O)=O)c1 Show InChI InChI=1S/C20H22N4O3/c1-15(25)23-8-3-9-24(11-10-23)19-14-21-13-18(22-19)17-5-2-4-16(12-17)6-7-20(26)27/h2,4-7,12-14H,3,8-11H2,1H3,(H,26,27)/b7-6+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	880	n/a	n/a	n/a	n/a	7.5	22
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...				J Med Chem 52: 1814-27 (2009) Article DOI: 10.1021/jm801242y BindingDB Entry DOI: 10.7270/Q25T3HS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM28414 ((2E)-3-(3-{6-[(2-acetamidoethyl)amino]pyrazin-2-yl...) Show SMILES CC(=O)NCCNc1cncc(n1)-c1cccc(\C=C\C(O)=O)c1 Show InChI InChI=1S/C17H18N4O3/c1-12(22)19-7-8-20-16-11-18-10-15(21-16)14-4-2-3-13(9-14)5-6-17(23)24/h2-6,9-11H,7-8H2,1H3,(H,19,22)(H,20,21)(H,23,24)/b6-5+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.02E+3	n/a	n/a	n/a	n/a	7.5	22
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...				J Med Chem 52: 1814-27 (2009) Article DOI: 10.1021/jm801242y BindingDB Entry DOI: 10.7270/Q25T3HS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM28400 ((2E)-3-{3-[6-(4-methyl-1,4-diazepan-1-yl)pyrazin-2...) Show SMILES CN1CCCN(CC1)c1cncc(n1)-c1cccc(\C=C\C(N)=O)c1 Show InChI InChI=1S/C19H23N5O/c1-23-8-3-9-24(11-10-23)19-14-21-13-17(22-19)16-5-2-4-15(12-16)6-7-18(20)25/h2,4-7,12-14H,3,8-11H2,1H3,(H2,20,25)/b7-6+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	7.5	22
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...				J Med Chem 52: 1814-27 (2009) Article DOI: 10.1021/jm801242y BindingDB Entry DOI: 10.7270/Q25T3HS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM28401 (3-{3-[6-(4-methyl-1,4-diazepan-1-yl)pyrazin-2-yl]p...) Show SMILES CN1CCCN(CC1)c1cncc(n1)-c1cccc(CCC(O)=O)c1 Show InChI InChI=1S/C19H24N4O2/c1-22-8-3-9-23(11-10-22)18-14-20-13-17(21-18)16-5-2-4-15(12-16)6-7-19(24)25/h2,4-5,12-14H,3,6-11H2,1H3,(H,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	MMDB PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	7.5	22
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...				J Med Chem 52: 1814-27 (2009) Article DOI: 10.1021/jm801242y BindingDB Entry DOI: 10.7270/Q25T3HS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM28409 ((2E)-3-{3-[6-(morpholin-4-yl)pyrazin-2-yl]phenyl}p...) Show SMILES OC(=O)\C=C\c1cccc(c1)-c1cncc(n1)N1CCOCC1 Show InChI InChI=1S/C17H17N3O3/c21-17(22)5-4-13-2-1-3-14(10-13)15-11-18-12-16(19-15)20-6-8-23-9-7-20/h1-5,10-12H,6-9H2,(H,21,22)/b5-4+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	7.5	22
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...				J Med Chem 52: 1814-27 (2009) Article DOI: 10.1021/jm801242y BindingDB Entry DOI: 10.7270/Q25T3HS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM28420 ((2E)-3-[3-(pyrazin-2-yl)phenyl]prop-2-enoic acid |...) Show SMILES OC(=O)\C=C\c1cccc(c1)-c1cnccn1 Show InChI InChI=1S/C13H10N2O2/c16-13(17)5-4-10-2-1-3-11(8-10)12-9-14-6-7-15-12/h1-9H,(H,16,17)/b5-4+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...				J Med Chem 52: 1814-27 (2009) Article DOI: 10.1021/jm801242y BindingDB Entry DOI: 10.7270/Q25T3HS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM28405 ((2E)-3-{3-[6-(azepan-1-yl)pyrazin-2-yl]phenyl}prop...) Show SMILES OC(=O)\C=C\c1cccc(c1)-c1cncc(n1)N1CCCCCC1 Show InChI InChI=1S/C19H21N3O2/c23-19(24)9-8-15-6-5-7-16(12-15)17-13-20-14-18(21-17)22-10-3-1-2-4-11-22/h5-9,12-14H,1-4,10-11H2,(H,23,24)/b9-8+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	7.5	22
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...				J Med Chem 52: 1814-27 (2009) Article DOI: 10.1021/jm801242y BindingDB Entry DOI: 10.7270/Q25T3HS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM28403 (1-methyl-4-(pyrazin-2-yl)-1,4-diazepane | pyrazine...) Show SMILES CN1CCCN(CC1)c1cnccn1 Show InChI InChI=1S/C10H16N4/c1-13-5-2-6-14(8-7-13)10-9-11-3-4-12-10/h3-4,9H,2,5-8H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>8.00E+3	n/a	n/a	n/a	n/a	7.5	22
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...				J Med Chem 52: 1814-27 (2009) Article DOI: 10.1021/jm801242y BindingDB Entry DOI: 10.7270/Q25T3HS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM28399 (methyl (2E)-3-{3-[6-(4-methyl-1,4-diazepan-1-yl)py...) Show SMILES COC(=O)\C=C\c1cccc(c1)-c1cncc(n1)N1CCCN(C)CC1 Show InChI InChI=1S/C20H24N4O2/c1-23-9-4-10-24(12-11-23)19-15-21-14-18(22-19)17-6-3-5-16(13-17)7-8-20(25)26-2/h3,5-8,13-15H,4,9-12H2,1-2H3/b8-7+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>8.00E+3	n/a	n/a	n/a	n/a	7.5	22
Boehringer Ingelheim Pharmaceuticals Inc.					Assay Description The activity of Pim kinase was measured in a homogeneous luciferase assay using GST-Pim, biotinylated peptide substrate and a luciferin-luciferase de...				J Med Chem 52: 1814-27 (2009) Article DOI: 10.1021/jm801242y BindingDB Entry DOI: 10.7270/Q25T3HS3
					More data for this Ligand-Target Pair