Compile Data Set for Download or QSAR

Found 35 hits with Last Name = 'wong' and Initial = 'kr'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM25743 (1-cycloheptyl-3-(1-acetylpiperidin-4-yl)urea | US8...) Show SMILES CC(=O)N1CCC(CC1)NC(=O)NC1CCCCCC1 Show InChI InChI=1S/C15H27N3O2/c1-12(19)18-10-8-14(9-11-18)17-15(20)16-13-6-4-2-3-5-7-13/h13-14H,2-11H2,1H3,(H2,16,17,20)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
Ar£te Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of human soluble epoxide hydrolase				Bioorg Med Chem Lett 21: 983-8 (2011) Article DOI: 10.1016/j.bmcl.2010.12.042 BindingDB Entry DOI: 10.7270/Q20865KB
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50335964 (1-(1-nicotinoylpiperidin-4-yl)-3-(4-(trifluorometh...) Show SMILES FC(F)(F)Oc1ccc(NC(=O)NC2CCN(CC2)C(=O)c2cccnc2)cc1 Show InChI InChI=1S/C19H19F3N4O3/c20-19(21,22)29-16-5-3-14(4-6-16)24-18(28)25-15-7-10-26(11-8-15)17(27)13-2-1-9-23-12-13/h1-6,9,12,15H,7-8,10-11H2,(H2,24,25,28)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Ar£te Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of human soluble epoxide hydrolase				Bioorg Med Chem Lett 21: 983-8 (2011) Article DOI: 10.1016/j.bmcl.2010.12.042 BindingDB Entry DOI: 10.7270/Q20865KB
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50335965 (1-(1-(isopropylsulfonyl)piperidin-4-yl)-3-(4-(trif...) Show SMILES CC(C)S(=O)(=O)N1CCC(CC1)NC(=O)Nc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C16H22F3N3O4S/c1-11(2)27(24,25)22-9-7-13(8-10-22)21-15(23)20-12-3-5-14(6-4-12)26-16(17,18)19/h3-6,11,13H,7-10H2,1-2H3,(H2,20,21,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Ar£te Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of human soluble epoxide hydrolase				Bioorg Med Chem Lett 21: 983-8 (2011) Article DOI: 10.1016/j.bmcl.2010.12.042 BindingDB Entry DOI: 10.7270/Q20865KB
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50335966 (1-Adamantan-1-yl-3-(1-methanesulfonyl-piperidin-4-...) Show SMILES CS(=O)(=O)N1CCC(CC1)NC(=O)NC12CC3CC(CC(C3)C1)C2 |TLB:17:18:16.21.15:22,THB:19:18:15:21.20.22,19:20:17.18.23:15,17:16:18.19.23:22| Show InChI InChI=1S/C17H29N3O3S/c1-24(22,23)20-4-2-15(3-5-20)18-16(21)19-17-9-12-6-13(10-17)8-14(7-12)11-17/h12-15H,2-11H2,1H3,(H2,18,19,21)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
Ar£te Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of human soluble epoxide hydrolase				Bioorg Med Chem Lett 21: 983-8 (2011) Article DOI: 10.1016/j.bmcl.2010.12.042 BindingDB Entry DOI: 10.7270/Q20865KB
					More data for this Ligand-Target Pair				3D Structure (crystal)
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50335967 (1-(1-(isopropylsulfonyl)piperidin-4-yl)-3-(4-(trif...) Show SMILES CC(C)S(=O)(=O)N1CCC(CC1)NC(=O)Nc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C16H22F3N3O3S/c1-11(2)26(24,25)22-9-7-14(8-10-22)21-15(23)20-13-5-3-12(4-6-13)16(17,18)19/h3-6,11,14H,7-10H2,1-2H3,(H2,20,21,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
Ar£te Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of human soluble epoxide hydrolase				Bioorg Med Chem Lett 21: 983-8 (2011) Article DOI: 10.1016/j.bmcl.2010.12.042 BindingDB Entry DOI: 10.7270/Q20865KB
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Mus musculus (Mouse))	BDBM50191854 (CHEMBL436774 | N-(1-acetyl-piperidin-4-yl)-N'-(ada...) Show SMILES CC(=O)N1CCC(CC1)NC(=O)NC12CC3CC(CC(C3)C1)C2 |TLB:12:13:16.15.20:18,THB:14:15:18:22.13.21,14:13:16.15.20:18,21:13:16:20.19.18,21:19:16:22.14.13,12:13:16:20.19.18| Show InChI InChI=1S/C18H29N3O2/c1-12(22)21-4-2-16(3-5-21)19-17(23)20-18-9-13-6-14(10-18)8-15(7-13)11-18/h13-16H,2-11H2,1H3,(H2,19,20,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Ar£te Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of mouse soluble epoxide hydrolase				Bioorg Med Chem Lett 21: 983-8 (2011) Article DOI: 10.1016/j.bmcl.2010.12.042 BindingDB Entry DOI: 10.7270/Q20865KB
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50335968 (1-(1-(methylsulfonyl)piperidin-4-yl)-3-(4-(trifluo...) Show SMILES CS(=O)(=O)N1CCC(CC1)NC(=O)Nc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C14H18F3N3O3S/c1-24(22,23)20-8-6-12(7-9-20)19-13(21)18-11-4-2-10(3-5-11)14(15,16)17/h2-5,12H,6-9H2,1H3,(H2,18,19,21)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Ar£te Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of human soluble epoxide hydrolase				Bioorg Med Chem Lett 21: 983-8 (2011) Article DOI: 10.1016/j.bmcl.2010.12.042 BindingDB Entry DOI: 10.7270/Q20865KB
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50335966 (1-Adamantan-1-yl-3-(1-methanesulfonyl-piperidin-4-...) Show SMILES CS(=O)(=O)N1CCC(CC1)NC(=O)NC12CC3CC(CC(C3)C1)C2 |TLB:17:18:16.21.15:22,THB:19:18:15:21.20.22,19:20:17.18.23:15,17:16:18.19.23:22| Show InChI InChI=1S/C17H29N3O3S/c1-24(22,23)20-4-2-15(3-5-20)18-16(21)19-17-9-12-6-13(10-17)8-14(7-12)11-17/h12-15H,2-11H2,1H3,(H2,18,19,21)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	n/a
Ar£te Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of soluble epoxide hydrolase in HUVEC assessed inhibition of as conversion of 14, 15-EET to 14, 15-DHET				Bioorg Med Chem Lett 21: 983-8 (2011) Article DOI: 10.1016/j.bmcl.2010.12.042 BindingDB Entry DOI: 10.7270/Q20865KB
					More data for this Ligand-Target Pair				3D Structure (crystal)
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50335969 (1-(1-acetylpiperidin-4-yl)-3-(4,4-dimethylcyclohex...) Show SMILES CC(=O)N1CCC(CC1)NC(=O)NC1CCC(C)(C)CC1 Show InChI InChI=1S/C16H29N3O2/c1-12(20)19-10-6-14(7-11-19)18-15(21)17-13-4-8-16(2,3)9-5-13/h13-14H,4-11H2,1-3H3,(H2,17,18,21)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Ar£te Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of human soluble epoxide hydrolase				Bioorg Med Chem Lett 21: 983-8 (2011) Article DOI: 10.1016/j.bmcl.2010.12.042 BindingDB Entry DOI: 10.7270/Q20865KB
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50335970 (1-cyclohexyl-3-(1-picolinoylpiperidin-4-yl)urea | ...) Show SMILES O=C(NC1CCCCC1)NC1CCN(CC1)C(=O)c1ccccn1 Show InChI InChI=1S/C18H26N4O2/c23-17(16-8-4-5-11-19-16)22-12-9-15(10-13-22)21-18(24)20-14-6-2-1-3-7-14/h4-5,8,11,14-15H,1-3,6-7,9-10,12-13H2,(H2,20,21,24)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.40	n/a	n/a	n/a	n/a	n/a	n/a
Ar£te Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of human soluble epoxide hydrolase				Bioorg Med Chem Lett 21: 983-8 (2011) Article DOI: 10.1016/j.bmcl.2010.12.042 BindingDB Entry DOI: 10.7270/Q20865KB
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50335964 (1-(1-nicotinoylpiperidin-4-yl)-3-(4-(trifluorometh...) Show SMILES FC(F)(F)Oc1ccc(NC(=O)NC2CCN(CC2)C(=O)c2cccnc2)cc1 Show InChI InChI=1S/C19H19F3N4O3/c20-19(21,22)29-16-5-3-14(4-6-16)24-18(28)25-15-7-10-26(11-8-15)17(27)13-2-1-9-23-12-13/h1-6,9,12,15H,7-8,10-11H2,(H2,24,25,28)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.70	n/a	n/a	n/a	n/a	n/a	n/a
Ar£te Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of soluble epoxide hydrolase in HUVEC assessed inhibition of as conversion of 14, 15-EET to 14, 15-DHET				Bioorg Med Chem Lett 21: 983-8 (2011) Article DOI: 10.1016/j.bmcl.2010.12.042 BindingDB Entry DOI: 10.7270/Q20865KB
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50191854 (CHEMBL436774 | N-(1-acetyl-piperidin-4-yl)-N'-(ada...) Show SMILES CC(=O)N1CCC(CC1)NC(=O)NC12CC3CC(CC(C3)C1)C2 |TLB:12:13:16.15.20:18,THB:14:15:18:22.13.21,14:13:16.15.20:18,21:13:16:20.19.18,21:19:16:22.14.13,12:13:16:20.19.18| Show InChI InChI=1S/C18H29N3O2/c1-12(22)21-4-2-16(3-5-21)19-17(23)20-18-9-13-6-14(10-18)8-15(7-13)11-18/h13-16H,2-11H2,1H3,(H2,19,20,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Ar£te Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of human soluble epoxide hydrolase				Bioorg Med Chem Lett 21: 983-8 (2011) Article DOI: 10.1016/j.bmcl.2010.12.042 BindingDB Entry DOI: 10.7270/Q20865KB
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50335971 (1-(1-acetylpiperidin-4-yl)-3-(3-(trifluoromethyl)p...) Show SMILES CC(=O)N1CCC(CC1)NC(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C15H18F3N3O2/c1-10(22)21-7-5-12(6-8-21)19-14(23)20-13-4-2-3-11(9-13)15(16,17)18/h2-4,9,12H,5-8H2,1H3,(H2,19,20,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Ar£te Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of human soluble epoxide hydrolase				Bioorg Med Chem Lett 21: 983-8 (2011) Article DOI: 10.1016/j.bmcl.2010.12.042 BindingDB Entry DOI: 10.7270/Q20865KB
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50335972 (1-(1-acetylpiperidin-4-yl)-3-(4-(trifluoromethyl)p...) Show SMILES CC(=O)N1CCC(CC1)NC(=O)Nc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C15H18F3N3O2/c1-10(22)21-8-6-13(7-9-21)20-14(23)19-12-4-2-11(3-5-12)15(16,17)18/h2-5,13H,6-9H2,1H3,(H2,19,20,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Ar£te Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of human soluble epoxide hydrolase				Bioorg Med Chem Lett 21: 983-8 (2011) Article DOI: 10.1016/j.bmcl.2010.12.042 BindingDB Entry DOI: 10.7270/Q20865KB
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM25744 (3-(1-acetylpiperidin-4-yl)-1-[4-(trifluoromethoxy)...) Show SMILES CC(=O)N1CCC(CC1)NC(=O)Nc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C15H18F3N3O3/c1-10(22)21-8-6-12(7-9-21)20-14(23)19-11-2-4-13(5-3-11)24-15(16,17)18/h2-5,12H,6-9H2,1H3,(H2,19,20,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Ar£te Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of human soluble epoxide hydrolase				Bioorg Med Chem Lett 21: 983-8 (2011) Article DOI: 10.1016/j.bmcl.2010.12.042 BindingDB Entry DOI: 10.7270/Q20865KB
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50335973 (1-(1-acetylpiperidin-4-yl)-3-(4-tert-butylcyclohex...) Show SMILES CC(=O)N1CCC(CC1)NC(=O)NC1CCC(CC1)C(C)(C)C |(1.63,-5.6,;1.57,-7.14,;.21,-7.87,;2.88,-7.96,;4.25,-7.24,;5.55,-8.05,;5.49,-9.6,;4.14,-10.32,;2.83,-9.51,;6.8,-10.41,;6.75,-11.95,;5.39,-12.68,;8.07,-12.76,;8.05,-14.31,;6.71,-15.06,;6.69,-16.59,;8.02,-17.38,;9.36,-16.62,;9.38,-15.08,;8,-18.92,;6.66,-19.67,;9.32,-19.7,;7.98,-20.45,)| Show InChI InChI=1S/C18H33N3O2/c1-13(22)21-11-9-16(10-12-21)20-17(23)19-15-7-5-14(6-8-15)18(2,3)4/h14-16H,5-12H2,1-4H3,(H2,19,20,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Ar£te Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of human soluble epoxide hydrolase				Bioorg Med Chem Lett 21: 983-8 (2011) Article DOI: 10.1016/j.bmcl.2010.12.042 BindingDB Entry DOI: 10.7270/Q20865KB
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50335967 (1-(1-(isopropylsulfonyl)piperidin-4-yl)-3-(4-(trif...) Show SMILES CC(C)S(=O)(=O)N1CCC(CC1)NC(=O)Nc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C16H22F3N3O3S/c1-11(2)26(24,25)22-9-7-14(8-10-22)21-15(23)20-13-5-3-12(4-6-13)16(17,18)19/h3-6,11,14H,7-10H2,1-2H3,(H2,20,21,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Ar£te Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of soluble epoxide hydrolase in HUVEC assessed inhibition of as conversion of 14, 15-EET to 14, 15-DHET				Bioorg Med Chem Lett 21: 983-8 (2011) Article DOI: 10.1016/j.bmcl.2010.12.042 BindingDB Entry DOI: 10.7270/Q20865KB
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50335974 (1-(1-Acetyl-piperidin-4-yl)-3-bicyclo[2.2.1]hept-7...) Show SMILES CC(=O)N1CCC(CC1)NC(=O)NC1C2CCC1CC2 Show InChI InChI=1S/C15H25N3O2/c1-10(19)18-8-6-13(7-9-18)16-15(20)17-14-11-2-3-12(14)5-4-11/h11-14H,2-9H2,1H3,(H2,16,17,20)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Ar£te Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of human soluble epoxide hydrolase				Bioorg Med Chem Lett 21: 983-8 (2011) Article DOI: 10.1016/j.bmcl.2010.12.042 BindingDB Entry DOI: 10.7270/Q20865KB
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50335975 (1-(1-Acetyl-piperidin-4-yl)-3-(4-methyl-bicyclo[2....) Show SMILES CC(=O)N1CCC(CC1)NC(=O)NC1CC2(C)CCC1CC2 |(19.45,7.01,;19.4,5.47,;18.03,4.74,;20.7,4.65,;22.06,5.37,;23.37,4.56,;23.3,3.02,;21.96,2.29,;20.65,3.11,;24.61,2.21,;24.57,.67,;23.21,-.06,;25.88,-.14,;25.86,-1.68,;26.33,-2.77,;26.12,-4.67,;26.14,-6.19,;27.5,-5.27,;27.19,-3.88,;25.83,-3.31,;24.39,-3.99,;24.61,-5.36,)| Show InChI InChI=1S/C17H29N3O2/c1-12(21)20-9-5-14(6-10-20)18-16(22)19-15-11-17(2)7-3-13(15)4-8-17/h13-15H,3-11H2,1-2H3,(H2,18,19,22)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Ar£te Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of human soluble epoxide hydrolase				Bioorg Med Chem Lett 21: 983-8 (2011) Article DOI: 10.1016/j.bmcl.2010.12.042 BindingDB Entry DOI: 10.7270/Q20865KB
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50335968 (1-(1-(methylsulfonyl)piperidin-4-yl)-3-(4-(trifluo...) Show SMILES CS(=O)(=O)N1CCC(CC1)NC(=O)Nc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C14H18F3N3O3S/c1-24(22,23)20-8-6-12(7-9-20)19-13(21)18-11-4-2-10(3-5-11)14(15,16)17/h2-5,12H,6-9H2,1H3,(H2,18,19,21)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Ar£te Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of soluble epoxide hydrolase in HUVEC assessed inhibition of as conversion of 14, 15-EET to 14, 15-DHET				Bioorg Med Chem Lett 21: 983-8 (2011) Article DOI: 10.1016/j.bmcl.2010.12.042 BindingDB Entry DOI: 10.7270/Q20865KB
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM25743 (1-cycloheptyl-3-(1-acetylpiperidin-4-yl)urea | US8...) Show SMILES CC(=O)N1CCC(CC1)NC(=O)NC1CCCCCC1 Show InChI InChI=1S/C15H27N3O2/c1-12(19)18-10-8-14(9-11-18)17-15(20)16-13-6-4-2-3-5-7-13/h13-14H,2-11H2,1H3,(H2,16,17,20)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Ar£te Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of soluble epoxide hydrolase in HUVEC assessed inhibition of as conversion of 14, 15-EET to 14, 15-DHET				Bioorg Med Chem Lett 21: 983-8 (2011) Article DOI: 10.1016/j.bmcl.2010.12.042 BindingDB Entry DOI: 10.7270/Q20865KB
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50335976 (1-(1-Acetyl-piperidin-4-yl)-3-cyclohexyl-urea | CH...) Show SMILES CC(=O)N1CCC(CC1)NC(=O)NC1CCCCC1 Show InChI InChI=1S/C14H25N3O2/c1-11(18)17-9-7-13(8-10-17)16-14(19)15-12-5-3-2-4-6-12/h12-13H,2-10H2,1H3,(H2,15,16,19)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Ar£te Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of human soluble epoxide hydrolase				Bioorg Med Chem Lett 21: 983-8 (2011) Article DOI: 10.1016/j.bmcl.2010.12.042 BindingDB Entry DOI: 10.7270/Q20865KB
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50335969 (1-(1-acetylpiperidin-4-yl)-3-(4,4-dimethylcyclohex...) Show SMILES CC(=O)N1CCC(CC1)NC(=O)NC1CCC(C)(C)CC1 Show InChI InChI=1S/C16H29N3O2/c1-12(20)19-10-6-14(7-11-19)18-15(21)17-13-4-8-16(2,3)9-5-13/h13-14H,4-11H2,1-3H3,(H2,17,18,21)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Ar£te Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of soluble epoxide hydrolase in HUVEC assessed inhibition of as conversion of 14, 15-EET to 14, 15-DHET				Bioorg Med Chem Lett 21: 983-8 (2011) Article DOI: 10.1016/j.bmcl.2010.12.042 BindingDB Entry DOI: 10.7270/Q20865KB
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50191854 (CHEMBL436774 | N-(1-acetyl-piperidin-4-yl)-N'-(ada...) Show SMILES CC(=O)N1CCC(CC1)NC(=O)NC12CC3CC(CC(C3)C1)C2 |TLB:12:13:16.15.20:18,THB:14:15:18:22.13.21,14:13:16.15.20:18,21:13:16:20.19.18,21:19:16:22.14.13,12:13:16:20.19.18| Show InChI InChI=1S/C18H29N3O2/c1-12(22)21-4-2-16(3-5-21)19-17(23)20-18-9-13-6-14(10-18)8-15(7-13)11-18/h13-16H,2-11H2,1H3,(H2,19,20,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
Ar£te Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of soluble epoxide hydrolase in HUVEC assessed inhibition of as conversion of 14, 15-EET to 14, 15-DHET				Bioorg Med Chem Lett 21: 983-8 (2011) Article DOI: 10.1016/j.bmcl.2010.12.042 BindingDB Entry DOI: 10.7270/Q20865KB
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50335977 (1-(1-Acetyl-piperidin-4-yl)-3-(3-fluoro-adamantan-...) Show SMILES CC(=O)N1CCC(CC1)NC(=O)NC12CC3CC(F)(CC(F)(C3)C1)C2 |TLB:16:17:23:22.15.14,18:17:23:22.15.14,18:17:20.22.23:14,21:20:17.16.24:14,THB:16:15:19.17.24:23,19:20:17.16.24:14,19:17:20.22.23:14| Show InChI InChI=1S/C18H27F2N3O2/c1-12(24)23-4-2-14(3-5-23)21-15(25)22-18-8-13-6-16(19,10-18)9-17(20,7-13)11-18/h13-14H,2-11H2,1H3,(H2,21,22,25)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Ar£te Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of human soluble epoxide hydrolase				Bioorg Med Chem Lett 21: 983-8 (2011) Article DOI: 10.1016/j.bmcl.2010.12.042 BindingDB Entry DOI: 10.7270/Q20865KB
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM25744 (3-(1-acetylpiperidin-4-yl)-1-[4-(trifluoromethoxy)...) Show SMILES CC(=O)N1CCC(CC1)NC(=O)Nc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C15H18F3N3O3/c1-10(22)21-8-6-12(7-9-21)20-14(23)19-11-2-4-13(5-3-11)24-15(16,17)18/h2-5,12H,6-9H2,1H3,(H2,19,20,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Ar£te Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of soluble epoxide hydrolase in HUVEC assessed inhibition of as conversion of 14, 15-EET to 14, 15-DHET				Bioorg Med Chem Lett 21: 983-8 (2011) Article DOI: 10.1016/j.bmcl.2010.12.042 BindingDB Entry DOI: 10.7270/Q20865KB
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50335965 (1-(1-(isopropylsulfonyl)piperidin-4-yl)-3-(4-(trif...) Show SMILES CC(C)S(=O)(=O)N1CCC(CC1)NC(=O)Nc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C16H22F3N3O4S/c1-11(2)27(24,25)22-9-7-13(8-10-22)21-15(23)20-12-3-5-14(6-4-12)26-16(17,18)19/h3-6,11,13H,7-10H2,1-2H3,(H2,20,21,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Ar£te Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of soluble epoxide hydrolase in HUVEC assessed inhibition of as conversion of 14, 15-EET to 14, 15-DHET				Bioorg Med Chem Lett 21: 983-8 (2011) Article DOI: 10.1016/j.bmcl.2010.12.042 BindingDB Entry DOI: 10.7270/Q20865KB
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50335970 (1-cyclohexyl-3-(1-picolinoylpiperidin-4-yl)urea | ...) Show SMILES O=C(NC1CCCCC1)NC1CCN(CC1)C(=O)c1ccccn1 Show InChI InChI=1S/C18H26N4O2/c23-17(16-8-4-5-11-19-16)22-12-9-15(10-13-22)21-18(24)20-14-6-2-1-3-7-14/h4-5,8,11,14-15H,1-3,6-7,9-10,12-13H2,(H2,20,21,24)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
Ar£te Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of soluble epoxide hydrolase in HUVEC assessed inhibition of as conversion of 14, 15-EET to 14, 15-DHET				Bioorg Med Chem Lett 21: 983-8 (2011) Article DOI: 10.1016/j.bmcl.2010.12.042 BindingDB Entry DOI: 10.7270/Q20865KB
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50335972 (1-(1-acetylpiperidin-4-yl)-3-(4-(trifluoromethyl)p...) Show SMILES CC(=O)N1CCC(CC1)NC(=O)Nc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C15H18F3N3O2/c1-10(22)21-8-6-13(7-9-21)20-14(23)19-12-4-2-11(3-5-12)15(16,17)18/h2-5,13H,6-9H2,1H3,(H2,19,20,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
Ar£te Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of soluble epoxide hydrolase in HUVEC assessed inhibition of as conversion of 14, 15-EET to 14, 15-DHET				Bioorg Med Chem Lett 21: 983-8 (2011) Article DOI: 10.1016/j.bmcl.2010.12.042 BindingDB Entry DOI: 10.7270/Q20865KB
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50335978 (1-(1-Acetyl-piperidin-4-yl)-3-(3,5,7-trifluoro-ada...) Show SMILES CC(=O)N1CCC(CC1)NC(=O)NC12CC3(F)CC(F)(CC(F)(C3)C1)C2 |TLB:17:18:23.15.14:24,23:21:15.17.14:25,23:15:21.20.24:25,THB:17:15:24:20.18.25,16:15:24:20.18.25,16:15:21.20.24:25,22:21:15.17.14:25,19:18:23.15.14:24| Show InChI InChI=1S/C18H26F3N3O2/c1-12(25)24-4-2-13(3-5-24)22-14(26)23-18-9-15(19)6-16(20,10-18)8-17(21,7-15)11-18/h13H,2-11H2,1H3,(H2,22,23,26)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Ar£te Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of human soluble epoxide hydrolase				Bioorg Med Chem Lett 21: 983-8 (2011) Article DOI: 10.1016/j.bmcl.2010.12.042 BindingDB Entry DOI: 10.7270/Q20865KB
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50335974 (1-(1-Acetyl-piperidin-4-yl)-3-bicyclo[2.2.1]hept-7...) Show SMILES CC(=O)N1CCC(CC1)NC(=O)NC1C2CCC1CC2 Show InChI InChI=1S/C15H25N3O2/c1-10(19)18-8-6-13(7-9-18)16-15(20)17-14-11-2-3-12(14)5-4-11/h11-14H,2-9H2,1H3,(H2,16,17,20)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Ar£te Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of soluble epoxide hydrolase in HUVEC assessed inhibition of as conversion of 14, 15-EET to 14, 15-DHET				Bioorg Med Chem Lett 21: 983-8 (2011) Article DOI: 10.1016/j.bmcl.2010.12.042 BindingDB Entry DOI: 10.7270/Q20865KB
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50335979 (1-(1-acetylpiperidin-4-yl)-3-(4,4-difluorocyclohex...) Show SMILES CC(=O)N1CCC(CC1)NC(=O)NC1CCC(F)(F)CC1 Show InChI InChI=1S/C14H23F2N3O2/c1-10(20)19-8-4-12(5-9-19)18-13(21)17-11-2-6-14(15,16)7-3-11/h11-12H,2-9H2,1H3,(H2,17,18,21)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	185	n/a	n/a	n/a	n/a	n/a	n/a
Ar£te Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of human soluble epoxide hydrolase				Bioorg Med Chem Lett 21: 983-8 (2011) Article DOI: 10.1016/j.bmcl.2010.12.042 BindingDB Entry DOI: 10.7270/Q20865KB
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50335971 (1-(1-acetylpiperidin-4-yl)-3-(3-(trifluoromethyl)p...) Show SMILES CC(=O)N1CCC(CC1)NC(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C15H18F3N3O2/c1-10(22)21-7-5-12(6-8-21)19-14(23)20-13-4-2-3-11(9-13)15(16,17)18/h2-4,9,12H,5-8H2,1H3,(H2,19,20,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	226	n/a	n/a	n/a	n/a	n/a	n/a
Ar£te Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of soluble epoxide hydrolase in HUVEC assessed inhibition of as conversion of 14, 15-EET to 14, 15-DHET				Bioorg Med Chem Lett 21: 983-8 (2011) Article DOI: 10.1016/j.bmcl.2010.12.042 BindingDB Entry DOI: 10.7270/Q20865KB
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50335973 (1-(1-acetylpiperidin-4-yl)-3-(4-tert-butylcyclohex...) Show SMILES CC(=O)N1CCC(CC1)NC(=O)NC1CCC(CC1)C(C)(C)C |(1.63,-5.6,;1.57,-7.14,;.21,-7.87,;2.88,-7.96,;4.25,-7.24,;5.55,-8.05,;5.49,-9.6,;4.14,-10.32,;2.83,-9.51,;6.8,-10.41,;6.75,-11.95,;5.39,-12.68,;8.07,-12.76,;8.05,-14.31,;6.71,-15.06,;6.69,-16.59,;8.02,-17.38,;9.36,-16.62,;9.38,-15.08,;8,-18.92,;6.66,-19.67,;9.32,-19.7,;7.98,-20.45,)| Show InChI InChI=1S/C18H33N3O2/c1-13(22)21-11-9-16(10-12-21)20-17(23)19-15-7-5-14(6-8-15)18(2,3)4/h14-16H,5-12H2,1-4H3,(H2,19,20,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Ar£te Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of soluble epoxide hydrolase in HUVEC assessed inhibition of as conversion of 14, 15-EET to 14, 15-DHET				Bioorg Med Chem Lett 21: 983-8 (2011) Article DOI: 10.1016/j.bmcl.2010.12.042 BindingDB Entry DOI: 10.7270/Q20865KB
					More data for this Ligand-Target Pair
Bifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50335975 (1-(1-Acetyl-piperidin-4-yl)-3-(4-methyl-bicyclo[2....) Show SMILES CC(=O)N1CCC(CC1)NC(=O)NC1CC2(C)CCC1CC2 |(19.45,7.01,;19.4,5.47,;18.03,4.74,;20.7,4.65,;22.06,5.37,;23.37,4.56,;23.3,3.02,;21.96,2.29,;20.65,3.11,;24.61,2.21,;24.57,.67,;23.21,-.06,;25.88,-.14,;25.86,-1.68,;26.33,-2.77,;26.12,-4.67,;26.14,-6.19,;27.5,-5.27,;27.19,-3.88,;25.83,-3.31,;24.39,-3.99,;24.61,-5.36,)| Show InChI InChI=1S/C17H29N3O2/c1-12(21)20-9-5-14(6-10-20)18-16(22)19-15-11-17(2)7-3-13(15)4-8-17/h13-15H,3-11H2,1-2H3,(H2,18,19,22)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Ar£te Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of soluble epoxide hydrolase in HUVEC assessed inhibition of as conversion of 14, 15-EET to 14, 15-DHET				Bioorg Med Chem Lett 21: 983-8 (2011) Article DOI: 10.1016/j.bmcl.2010.12.042 BindingDB Entry DOI: 10.7270/Q20865KB
					More data for this Ligand-Target Pair