Compile Data Set for Download or QSAR

Found 64 hits with Last Name = 'yoshioka' and Initial = 'y'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
E3 ubiquitin-protein ligase XIAP [241-356] (Homo sapiens (Human))	BDBM13152 ((2S)-1-[(2S)-2-[(2S)-2-aminobutanamido]-3-methylbu...) Show SMILES CC[C@H](N)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)NC(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C27H36N4O3/c1-4-21(28)25(32)29-23(18(2)3)27(34)31-17-11-16-22(31)26(33)30-24(19-12-7-5-8-13-19)20-14-9-6-10-15-20/h5-10,12-15,18,21-24H,4,11,16-17,28H2,1-3H3,(H,29,32)(H,30,33)/t21-,22-,23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	24	-43.1	n/a	n/a	n/a	n/a	n/a	7.5	22
University of Michigan					Assay Description A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...				Bioorg Med Chem Lett 15: 793-7 (2005) Article DOI: 10.1016/j.bmcl.2004.11.008 BindingDB Entry DOI: 10.7270/Q2H41PP8
					More data for this Ligand-Target Pair				3D Structure (docked)
E3 ubiquitin-protein ligase XIAP [241-356] (Homo sapiens (Human))	BDBM13151 ((2S)-1-[(2S)-2-[(2S)-2-aminopropanamido]-3-methylb...) Show SMILES CC(C)[C@H](NC(=O)[C@H](C)N)C(=O)N1CCC[C@H]1C(=O)NC(c1ccccc1)c1ccccc1 |r| Show InChI InChI=1S/C26H34N4O3/c1-17(2)22(28-24(31)18(3)27)26(33)30-16-10-15-21(30)25(32)29-23(19-11-6-4-7-12-19)20-13-8-5-9-14-20/h4-9,11-14,17-18,21-23H,10,15-16,27H2,1-3H3,(H,28,31)(H,29,32)/t18-,21-,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	28	-42.7	n/a	n/a	n/a	n/a	n/a	7.5	22
University of Michigan					Assay Description A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...				Bioorg Med Chem Lett 15: 793-7 (2005) Article DOI: 10.1016/j.bmcl.2004.11.008 BindingDB Entry DOI: 10.7270/Q2H41PP8
					More data for this Ligand-Target Pair				3D Structure (docked)
E3 ubiquitin-protein ligase XIAP [241-356] (Homo sapiens (Human))	BDBM13155 ((2S)-1-[(2S)-2-[(2S)-2-aminobutanamido]-3-methylbu...) Show SMILES CC[C@H](N)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C21H32N4O3/c1-4-16(22)19(26)24-18(14(2)3)21(28)25-12-8-11-17(25)20(27)23-13-15-9-6-5-7-10-15/h5-7,9-10,14,16-18H,4,8,11-13,22H2,1-3H3,(H,23,27)(H,24,26)/t16-,17-,18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	81	-40.1	n/a	n/a	n/a	n/a	n/a	7.5	22
University of Michigan					Assay Description A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...				Bioorg Med Chem Lett 15: 793-7 (2005) Article DOI: 10.1016/j.bmcl.2004.11.008 BindingDB Entry DOI: 10.7270/Q2H41PP8
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP [241-356] (Homo sapiens (Human))	BDBM13150 ((2S)-1-[(2S)-2-[(2S)-2-aminopropanamido]-3-methylb...) Show SMILES CC(C)[C@H](NC(=O)[C@H](C)N)C(=O)N1CCC[C@H]1C(=O)NCCc1ccccc1 |r| Show InChI InChI=1S/C21H32N4O3/c1-14(2)18(24-19(26)15(3)22)21(28)25-13-7-10-17(25)20(27)23-12-11-16-8-5-4-6-9-16/h4-6,8-9,14-15,17-18H,7,10-13,22H2,1-3H3,(H,23,27)(H,24,26)/t15-,17-,18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	150	-38.6	n/a	n/a	n/a	n/a	n/a	7.5	22
University of Michigan					Assay Description A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...				Bioorg Med Chem Lett 15: 793-7 (2005) Article DOI: 10.1016/j.bmcl.2004.11.008 BindingDB Entry DOI: 10.7270/Q2H41PP8
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP [241-356] (Homo sapiens (Human))	BDBM13148 ((2S)-1-[(2S)-2-[(2S)-2-aminopropanamido]-3-methylb...) Show SMILES CC(C)[C@H](NC(=O)[C@H](C)N)C(=O)N1CCC[C@H]1C(=O)NCc1cccs1 |r| Show InChI InChI=1S/C18H28N4O3S/c1-11(2)15(21-16(23)12(3)19)18(25)22-8-4-7-14(22)17(24)20-10-13-6-5-9-26-13/h5-6,9,11-12,14-15H,4,7-8,10,19H2,1-3H3,(H,20,24)(H,21,23)/t12-,14-,15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	180	-38.1	n/a	n/a	n/a	n/a	n/a	7.5	22
University of Michigan					Assay Description A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...				Bioorg Med Chem Lett 15: 793-7 (2005) Article DOI: 10.1016/j.bmcl.2004.11.008 BindingDB Entry DOI: 10.7270/Q2H41PP8
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP [241-356] (Homo sapiens (Human))	BDBM13147 ((2S)-1-[(2S)-2-[(2S)-2-aminopropanamido]-3-methylb...) Show SMILES CC(C)[C@H](NC(=O)[C@H](C)N)C(=O)N1CCC[C@H]1C(=O)NCc1ccco1 |r| Show InChI InChI=1S/C18H28N4O4/c1-11(2)15(21-16(23)12(3)19)18(25)22-8-4-7-14(22)17(24)20-10-13-6-5-9-26-13/h5-6,9,11-12,14-15H,4,7-8,10,19H2,1-3H3,(H,20,24)(H,21,23)/t12-,14-,15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	220	-37.6	n/a	n/a	n/a	n/a	n/a	7.5	22
University of Michigan					Assay Description A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...				Bioorg Med Chem Lett 15: 793-7 (2005) Article DOI: 10.1016/j.bmcl.2004.11.008 BindingDB Entry DOI: 10.7270/Q2H41PP8
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP [241-356] (Homo sapiens (Human))	BDBM13142 ((2S)-1-[(2S)-2-[(2S)-2-aminopropanamido]-3-methylb...) Show SMILES CC(C)[C@H](NC(=O)[C@H](C)N)C(=O)N1CCC[C@H]1C(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C20H30N4O3/c1-13(2)17(23-18(25)14(3)21)20(27)24-11-7-10-16(24)19(26)22-12-15-8-5-4-6-9-15/h4-6,8-9,13-14,16-17H,7,10-12,21H2,1-3H3,(H,22,26)(H,23,25)/t14-,16-,17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	290	-36.9	n/a	n/a	n/a	n/a	n/a	7.5	22
University of Michigan					Assay Description A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...				Bioorg Med Chem Lett 15: 793-7 (2005) Article DOI: 10.1016/j.bmcl.2004.11.008 BindingDB Entry DOI: 10.7270/Q2H41PP8
					More data for this Ligand-Target Pair
Sentrin-specific protease 1 (Homo sapiens (Human))	BDBM50437693 (VIALININ A) Show SMILES Oc1ccc(cc1)-c1c(O)c(O)c(-c2ccc(O)cc2)c(OC(=O)Cc2ccccc2)c1OC(=O)Cc1ccccc1 Show InChI InChI=1S/C34H26O8/c35-25-15-11-23(12-16-25)29-31(39)32(40)30(24-13-17-26(36)18-14-24)34(42-28(38)20-22-9-5-2-6-10-22)33(29)41-27(37)19-21-7-3-1-4-8-21/h1-18,35-36,39-40H,19-20H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	930	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo University of Agriculture Curated by ChEMBL					Assay Description Binding affinity to recombinant human 6His-tagged SENP1 catalytic domain expressed in Escherichia coli				Bioorg Med Chem Lett 26: 4237-40 (2016) Article DOI: 10.1016/j.bmcl.2016.07.051 BindingDB Entry DOI: 10.7270/Q2SF30PB
					More data for this Ligand-Target Pair
Sentrin-specific protease 1 (Homo sapiens (Human))	BDBM50437693 (VIALININ A) Show SMILES Oc1ccc(cc1)-c1c(O)c(O)c(-c2ccc(O)cc2)c(OC(=O)Cc2ccccc2)c1OC(=O)Cc1ccccc1 Show InChI InChI=1S/C34H26O8/c35-25-15-11-23(12-16-25)29-31(39)32(40)30(24-13-17-26(36)18-14-24)34(42-28(38)20-22-9-5-2-6-10-22)33(29)41-27(37)19-21-7-3-1-4-8-21/h1-18,35-36,39-40H,19-20H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	1.07E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo University of Agriculture Curated by ChEMBL					Assay Description Binding affinity to full-length recombinant human 6His-tagged SENP1 expressed in Escherichia coli BL21 (DE3)				Bioorg Med Chem Lett 26: 4237-40 (2016) Article DOI: 10.1016/j.bmcl.2016.07.051 BindingDB Entry DOI: 10.7270/Q2SF30PB
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP [241-356] (Homo sapiens (Human))	BDBM13153 ((2S)-2-amino-N-[(2S)-3-methyl-1-oxo-1-[(2R)-2-(3-p...) Show SMILES CC(C)[C@H](NC(=O)[C@H](C)N)C(=O)N1CCC[C@H]1CCCc1ccccc1 |r| Show InChI InChI=1S/C21H33N3O2/c1-15(2)19(23-20(25)16(3)22)21(26)24-14-8-13-18(24)12-7-11-17-9-5-4-6-10-17/h4-6,9-10,15-16,18-19H,7-8,11-14,22H2,1-3H3,(H,23,25)/t16-,18+,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	1.20E+3	-33.5	n/a	n/a	n/a	n/a	n/a	7.5	22
University of Michigan					Assay Description A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...				Bioorg Med Chem Lett 15: 793-7 (2005) Article DOI: 10.1016/j.bmcl.2004.11.008 BindingDB Entry DOI: 10.7270/Q2H41PP8
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP [241-356] (Homo sapiens (Human))	BDBM13146 ((2S)-1-[(2S)-2-[(2S)-2-aminopropanamido]-3-methylb...) Show SMILES CC(C)[C@H](NC(=O)[C@H](C)N)C(=O)N1CCC[C@H]1C(=O)NCC1CCCCC1 |r| Show InChI InChI=1S/C20H36N4O3/c1-13(2)17(23-18(25)14(3)21)20(27)24-11-7-10-16(24)19(26)22-12-15-8-5-4-6-9-15/h13-17H,4-12,21H2,1-3H3,(H,22,26)(H,23,25)/t14-,16-,17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	1.27E+3	-33.3	n/a	n/a	n/a	n/a	n/a	7.5	22
University of Michigan					Assay Description A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...				Bioorg Med Chem Lett 15: 793-7 (2005) Article DOI: 10.1016/j.bmcl.2004.11.008 BindingDB Entry DOI: 10.7270/Q2H41PP8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 5 (Homo sapiens (Human))	BDBM50437693 (VIALININ A) Show SMILES Oc1ccc(cc1)-c1c(O)c(O)c(-c2ccc(O)cc2)c(OC(=O)Cc2ccccc2)c1OC(=O)Cc1ccccc1 Show InChI InChI=1S/C34H26O8/c35-25-15-11-23(12-16-25)29-31(39)32(40)30(24-13-17-26(36)18-14-24)34(42-28(38)20-22-9-5-2-6-10-22)33(29)41-27(37)19-21-7-3-1-4-8-21/h1-18,35-36,39-40H,19-20H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo University of Agriculture Curated by ChEMBL					Assay Description Inhibition of wild type human USP5 expressed in Escherichia coli BL21(DE3) using Ub-AMC as substrate after 60 mins by fluorometric analysis				Bioorg Med Chem Lett 23: 4328-31 (2013) Article DOI: 10.1016/j.bmcl.2013.05.093 BindingDB Entry DOI: 10.7270/Q2T15528
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP [241-356] (Homo sapiens (Human))	BDBM13156 ((2S)-1-[(2S)-2-[(2S)-2-amino-3-methylbutanamido]-3...) Show SMILES CC(C)[C@H](N)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C22H34N4O3/c1-14(2)18(23)21(28)25-19(15(3)4)22(29)26-12-8-11-17(26)20(27)24-13-16-9-6-5-7-10-16/h5-7,9-10,14-15,17-19H,8,11-13,23H2,1-4H3,(H,24,27)(H,25,28)/t17-,18-,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	4.15E+3	-30.4	n/a	n/a	n/a	n/a	n/a	7.5	22
University of Michigan					Assay Description A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...				Bioorg Med Chem Lett 15: 793-7 (2005) Article DOI: 10.1016/j.bmcl.2004.11.008 BindingDB Entry DOI: 10.7270/Q2H41PP8
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP [241-356] (Homo sapiens (Human))	BDBM13145 ((2S)-1-[(2S)-2-[(2S)-2-aminopropanamido]-3-methylb...) Show SMILES CC(C)[C@H](NC(=O)[C@H](C)N)C(=O)N1CCC[C@H]1C(=O)NCC1CC1 |r| Show InChI InChI=1S/C17H30N4O3/c1-10(2)14(20-15(22)11(3)18)17(24)21-8-4-5-13(21)16(23)19-9-12-6-7-12/h10-14H,4-9,18H2,1-3H3,(H,19,23)(H,20,22)/t11-,13-,14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	4.41E+3	-30.3	n/a	n/a	n/a	n/a	n/a	7.5	22
University of Michigan					Assay Description A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...				Bioorg Med Chem Lett 15: 793-7 (2005) Article DOI: 10.1016/j.bmcl.2004.11.008 BindingDB Entry DOI: 10.7270/Q2H41PP8
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP [241-356] (Homo sapiens (Human))	BDBM13149 ((2S)-1-[(2S)-2-[(2S)-2-aminopropanamido]-3-methylb...) Show SMILES CC(C)[C@H](NC(=O)[C@H](C)N)C(=O)N1CCC[C@H]1C(=O)Nc1ccccc1 |r| Show InChI InChI=1S/C19H28N4O3/c1-12(2)16(22-17(24)13(3)20)19(26)23-11-7-10-15(23)18(25)21-14-8-5-4-6-9-14/h4-6,8-9,12-13,15-16H,7,10-11,20H2,1-3H3,(H,21,25)(H,22,24)/t13-,15-,16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	4.90E+3	-30.0	n/a	n/a	n/a	n/a	n/a	7.5	22
University of Michigan					Assay Description A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...				Bioorg Med Chem Lett 15: 793-7 (2005) Article DOI: 10.1016/j.bmcl.2004.11.008 BindingDB Entry DOI: 10.7270/Q2H41PP8
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 5 (Homo sapiens (Human))	BDBM50437693 (VIALININ A) Show SMILES Oc1ccc(cc1)-c1c(O)c(O)c(-c2ccc(O)cc2)c(OC(=O)Cc2ccccc2)c1OC(=O)Cc1ccccc1 Show InChI InChI=1S/C34H26O8/c35-25-15-11-23(12-16-25)29-31(39)32(40)30(24-13-17-26(36)18-14-24)34(42-28(38)20-22-9-5-2-6-10-22)33(29)41-27(37)19-21-7-3-1-4-8-21/h1-18,35-36,39-40H,19-20H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo University of Agriculture Curated by ChEMBL					Assay Description Competitive inhibition of wild type human USP5 expressed in Escherichia coli BL21(DE3) using Ub-AMC as substrate				Bioorg Med Chem Lett 23: 4328-31 (2013) Article DOI: 10.1016/j.bmcl.2013.05.093 BindingDB Entry DOI: 10.7270/Q2T15528
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP [241-356] (Homo sapiens (Human))	BDBM13143 ((2S)-1-[(2S)-2-[(2S)-2-aminopropanamido]-3-methylb...) Show SMILES CC(C)CNC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](C)N)C(C)C |r| Show InChI InChI=1S/C17H32N4O3/c1-10(2)9-19-16(23)13-7-6-8-21(13)17(24)14(11(3)4)20-15(22)12(5)18/h10-14H,6-9,18H2,1-5H3,(H,19,23)(H,20,22)/t12-,13-,14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	1.34E+4	-27.5	n/a	n/a	n/a	n/a	n/a	7.5	22
University of Michigan					Assay Description A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...				Bioorg Med Chem Lett 15: 793-7 (2005) Article DOI: 10.1016/j.bmcl.2004.11.008 BindingDB Entry DOI: 10.7270/Q2H41PP8
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP [241-356] (Homo sapiens (Human))	BDBM13144 ((2S)-1-[(2S)-2-[(2S)-2-aminopropanamido]-3-methylb...) Show SMILES CCC(CC)CNC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](C)N)C(C)C |r| Show InChI InChI=1S/C19H36N4O3/c1-6-14(7-2)11-21-18(25)15-9-8-10-23(15)19(26)16(12(3)4)22-17(24)13(5)20/h12-16H,6-11,20H2,1-5H3,(H,21,25)(H,22,24)/t13-,15-,16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	2.45E+4	-26.1	n/a	n/a	n/a	n/a	n/a	7.5	22
University of Michigan					Assay Description A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...				Bioorg Med Chem Lett 15: 793-7 (2005) Article DOI: 10.1016/j.bmcl.2004.11.008 BindingDB Entry DOI: 10.7270/Q2H41PP8
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP [241-356] (Homo sapiens (Human))	BDBM13157 ((2S)-1-[(2S)-2-[(2S)-2-aminopentanamido]-3-methylb...) Show SMILES CCC[C@H](N)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C22H34N4O3/c1-4-9-17(23)20(27)25-19(15(2)3)22(29)26-13-8-12-18(26)21(28)24-14-16-10-6-5-7-11-16/h5-7,10-11,15,17-19H,4,8-9,12-14,23H2,1-3H3,(H,24,28)(H,25,27)/t17-,18-,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	5.40E+4	-24.1	n/a	n/a	n/a	n/a	n/a	7.5	22
University of Michigan					Assay Description A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...				Bioorg Med Chem Lett 15: 793-7 (2005) Article DOI: 10.1016/j.bmcl.2004.11.008 BindingDB Entry DOI: 10.7270/Q2H41PP8
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase XIAP [241-356] (Homo sapiens (Human))	BDBM13154 ((2S)-1-[(2S)-2-(2-aminoacetamido)-3-methylbutanoyl...) Show SMILES CC(C)[C@H](NC(=O)CN)C(=O)N1CCC[C@H]1C(=O)NCCc1ccccc1 |r| Show InChI InChI=1S/C20H30N4O3/c1-14(2)18(23-17(25)13-21)20(27)24-12-6-9-16(24)19(26)22-11-10-15-7-4-3-5-8-15/h3-5,7-8,14,16,18H,6,9-13,21H2,1-2H3,(H,22,26)(H,23,25)/t16-,18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	6.80E+4	-23.5	n/a	n/a	n/a	n/a	n/a	7.5	22
University of Michigan					Assay Description A quantitative in vitro binding assay using the fluorescence polarization (FP) based method was developed and used to determine the binding affinity ...				Bioorg Med Chem Lett 15: 793-7 (2005) Article DOI: 10.1016/j.bmcl.2004.11.008 BindingDB Entry DOI: 10.7270/Q2H41PP8
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50005232 ((R)-2-{[Acetyl-(2-methoxy-3-octadecylcarbamoyloxy-...) Show SMILES CCCCCCCCCCCCCCCCCCNC(=O)OCC(COC(=O)N(Cc1cccc[n+]1CC)C(C)=O)OC Show InChI InChI=1S/C34H59N3O6/c1-5-7-8-9-10-11-12-13-14-15-16-17-18-19-20-22-25-35-33(39)42-28-32(41-4)29-43-34(40)37(30(3)38)27-31-24-21-23-26-36(31)6-2/h21,23-24,26,32H,5-20,22,25,27-29H2,1-4H3/p+1	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Chemical Industries Ltd. Curated by ChEMBL					Assay Description Inhibition of rabbit platelet aggregation induced by platelet activating factor (PAF)				J Med Chem 32: 56-64 (1989) BindingDB Entry DOI: 10.7270/Q2ZP46QM
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50367841 (CHEMBL1788193) Show SMILES CCCCCCCCCCCCCCCCCCNC(=O)OC[C@H](COC(=O)N(Cc1cccc[n+]1CC)C(C)=O)OC |r| Show InChI InChI=1S/C34H59N3O6/c1-5-7-8-9-10-11-12-13-14-15-16-17-18-19-20-22-25-35-33(39)42-28-32(41-4)29-43-34(40)37(30(3)38)27-31-24-21-23-26-36(31)6-2/h21,23-24,26,32H,5-20,22,25,27-29H2,1-4H3/p+1/t32-/m1/s1	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Chemical Industries Ltd. Curated by ChEMBL					Assay Description Inhibition of rabbit platelet aggregation induced by platelet activating factor (PAF)				J Med Chem 32: 56-64 (1989) BindingDB Entry DOI: 10.7270/Q2ZP46QM
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50405738 (CHEMBL2093039) Show SMILES CCCCCCCCCCCCCCCCCCNC(=O)OC[C@@H](COC(=O)N(Cc1cccc[n+]1CC)C(C)=O)OC |r| Show InChI InChI=1S/C34H59N3O6/c1-5-7-8-9-10-11-12-13-14-15-16-17-18-19-20-22-25-35-33(39)42-28-32(41-4)29-43-34(40)37(30(3)38)27-31-24-21-23-26-36(31)6-2/h21,23-24,26,32H,5-20,22,25,27-29H2,1-4H3/p+1/t32-/m0/s1	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	91	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Chemical Industries Ltd. Curated by ChEMBL					Assay Description Inhibition of rabbit platelet aggregation induced by platelet activating factor (PAF)				J Med Chem 32: 56-64 (1989) BindingDB Entry DOI: 10.7270/Q2ZP46QM
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50020324 (4-{[Acetyl-(2-methoxy-3-octadecylcarbamoyloxy-prop...) Show SMILES CCCCCCCCCCCCCCCCCCNC(=O)OCC(COC(=O)N(Cc1csc[n+]1CC)C(C)=O)OC Show InChI InChI=1S/C32H57N3O6S/c1-5-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-33-31(37)40-24-30(39-4)25-41-32(38)35(28(3)36)23-29-26-42-27-34(29)6-2/h26-27,30H,5-25H2,1-4H3/p+1	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Chemical Industries Ltd. Curated by ChEMBL					Assay Description Inhibition of rabbit platelet aggregation induced by platelet activating factor (PAF)				J Med Chem 32: 56-64 (1989) BindingDB Entry DOI: 10.7270/Q2ZP46QM
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50020321 (2-{[Acetyl-(2-methoxy-3-octadecylcarbamoyloxy-prop...) Show SMILES CCCCCCCCCCCCCCCCCCNC(=O)OCC(COC(=O)N(Cc1cccc[n+]1CCC)C(C)=O)OC Show InChI InChI=1S/C35H61N3O6/c1-5-7-8-9-10-11-12-13-14-15-16-17-18-19-20-22-25-36-34(40)43-29-33(42-4)30-44-35(41)38(31(3)39)28-32-24-21-23-27-37(32)26-6-2/h21,23-24,27,33H,5-20,22,25-26,28-30H2,1-4H3/p+1	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Chemical Industries Ltd. Curated by ChEMBL					Assay Description Inhibition of rabbit platelet aggregation induced by platelet activating factor (PAF)				J Med Chem 32: 56-64 (1989) BindingDB Entry DOI: 10.7270/Q2ZP46QM
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50020318 (2-{[Acetyl-(2-methoxy-3-octadecylcarbamoyloxy-prop...) Show SMILES CCCCCCCCCCCCCCCCCCNC(=O)OCC(COC(=O)N(Cc1scc[n+]1CC)C(C)=O)OC Show InChI InChI=1S/C32H57N3O6S/c1-5-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-33-31(37)40-26-29(39-4)27-41-32(38)35(28(3)36)25-30-34(6-2)23-24-42-30/h23-24,29H,5-22,25-27H2,1-4H3/p+1	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Chemical Industries Ltd. Curated by ChEMBL					Assay Description Inhibition of rabbit platelet aggregation induced by platelet activating factor (PAF)				J Med Chem 32: 56-64 (1989) BindingDB Entry DOI: 10.7270/Q2ZP46QM
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50020337 (4-{[Acetyl-(2-methoxy-3-octadecylcarbamoyloxy-prop...) Show SMILES CCCCCCCCCCCCCCCCCCNC(=O)OCC(COC(=O)N(Cc1csc[n+]1C)C(C)=O)OC Show InChI InChI=1S/C31H55N3O6S/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-32-30(36)39-23-29(38-4)24-40-31(37)34(27(2)35)22-28-25-41-26-33(28)3/h25-26,29H,5-24H2,1-4H3/p+1	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Chemical Industries Ltd. Curated by ChEMBL					Assay Description Inhibition of rabbit platelet aggregation induced by platelet activating factor (PAF)				J Med Chem 32: 56-64 (1989) BindingDB Entry DOI: 10.7270/Q2ZP46QM
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50020328 (2-{[Acetyl-(2-methoxy-3-octadecylcarbamoyloxy-prop...) Show SMILES CCCCCCCCCCCCCCCCCCNC(=O)OCC(COC(=O)N(Cc1cccc[n+]1CCCC)C(C)=O)OC Show InChI InChI=1S/C36H63N3O6/c1-5-7-9-10-11-12-13-14-15-16-17-18-19-20-21-23-26-37-35(41)44-30-34(43-4)31-45-36(42)39(32(3)40)29-33-25-22-24-28-38(33)27-8-6-2/h22,24-25,28,34H,5-21,23,26-27,29-31H2,1-4H3/p+1	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Chemical Industries Ltd. Curated by ChEMBL					Assay Description Inhibition of rabbit platelet aggregation induced by platelet activating factor (PAF)				J Med Chem 32: 56-64 (1989) BindingDB Entry DOI: 10.7270/Q2ZP46QM
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50020325 (2-{[Acetyl-(2-methoxy-3-octadecylcarbamoyloxy-prop...) Show SMILES CCCCCCCCCCCCCCCCCCNC(=O)OCC(COC(=O)N(Cc1cccc[n+]1C)C(C)=O)OC Show InChI InChI=1S/C33H57N3O6/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-24-34-32(38)41-27-31(40-4)28-42-33(39)36(29(2)37)26-30-23-20-22-25-35(30)3/h20,22-23,25,31H,5-19,21,24,26-28H2,1-4H3/p+1	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Chemical Industries Ltd. Curated by ChEMBL					Assay Description Inhibition of rabbit platelet aggregation induced by platelet activating factor (PAF)				J Med Chem 32: 56-64 (1989) BindingDB Entry DOI: 10.7270/Q2ZP46QM
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50020340 (2-{[Acetyl-(2-methoxy-3-octadecylcarbamoyloxy-prop...) Show SMILES CCCCCCCCCCCCCCCCCCNC(=O)OCC(COC(=O)N(Cc1scc[n+]1C)C(C)=O)OC Show InChI InChI=1S/C31H55N3O6S/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-32-30(36)39-25-28(38-4)26-40-31(37)34(27(2)35)24-29-33(3)22-23-41-29/h22-23,28H,5-21,24-26H2,1-4H3/p+1	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Chemical Industries Ltd. Curated by ChEMBL					Assay Description Inhibition of rabbit platelet aggregation induced by platelet activating factor (PAF)				J Med Chem 32: 56-64 (1989) BindingDB Entry DOI: 10.7270/Q2ZP46QM
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50020327 (2-{[Acetyl-(2-methoxy-3-octadecylcarbamoyloxy-prop...) Show SMILES CCCCCCCCCCCCCCCCCCNC(=O)OCC(COC(=O)N(CC1CCC[N+]1(C)CC)C(C)=O)OC Show InChI InChI=1S/C34H65N3O6/c1-6-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-25-35-33(39)42-28-32(41-5)29-43-34(40)36(30(3)38)27-31-24-23-26-37(31,4)7-2/h31-32H,6-29H2,1-5H3/p+1	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	670	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Chemical Industries Ltd. Curated by ChEMBL					Assay Description Inhibition of rabbit platelet aggregation induced by platelet activating factor (PAF)				J Med Chem 32: 56-64 (1989) BindingDB Entry DOI: 10.7270/Q2ZP46QM
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50020332 (CHEMBL158254 | {2-[(2-Acetoxy-3-octadecyloxy-propo...) Show SMILES CCCCCCCCCCCCCCCCCCOCC(COC(=O)N(CC[N+](C)(C)C)C(C)=O)OC(C)=O Show InChI InChI=1S/C31H61N2O6/c1-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-25-37-26-30(39-29(3)35)27-38-31(36)32(28(2)34)23-24-33(4,5)6/h30H,7-27H2,1-6H3/q+1	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	880	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Chemical Industries Ltd. Curated by ChEMBL					Assay Description Inhibition of rabbit platelet aggregation induced by platelet activating factor (PAF)				J Med Chem 32: 56-64 (1989) BindingDB Entry DOI: 10.7270/Q2ZP46QM
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50020330 (1-{2-[Acetyl-(2-methoxy-3-octadecylcarbamoyloxy-pr...) Show SMILES CCCCCCCCCCCCCCCCCCNC(=O)OCC(COC(=O)N(CC[N+]1(C)CCCC1)C(C)=O)OC Show InChI InChI=1S/C33H63N3O6/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-23-34-32(38)41-28-31(40-4)29-42-33(39)35(30(2)37)24-27-36(3)25-21-22-26-36/h31H,5-29H2,1-4H3/p+1	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Chemical Industries Ltd. Curated by ChEMBL					Assay Description Inhibition of rabbit platelet aggregation induced by platelet activating factor (PAF)				J Med Chem 32: 56-64 (1989) BindingDB Entry DOI: 10.7270/Q2ZP46QM
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50020329 (CHEMBL158489 | {2-[Acetyl-(2-methoxy-3-octadecylca...) Show SMILES CCCCCCCCCCCCCCCCCCNC(=O)OCC(COC(=O)N(CC[N+](C)(C)C)C(C)=O)OC Show InChI InChI=1S/C31H61N3O6/c1-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-32-30(36)39-26-29(38-6)27-40-31(37)33(28(2)35)24-25-34(3,4)5/h29H,7-27H2,1-6H3/p+1	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Chemical Industries Ltd. Curated by ChEMBL					Assay Description Inhibition of rabbit platelet aggregation induced by platelet activating factor (PAF)				J Med Chem 32: 56-64 (1989) BindingDB Entry DOI: 10.7270/Q2ZP46QM
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 4 (Homo sapiens (Human))	BDBM50437693 (VIALININ A) Show SMILES Oc1ccc(cc1)-c1c(O)c(O)c(-c2ccc(O)cc2)c(OC(=O)Cc2ccccc2)c1OC(=O)Cc1ccccc1 Show InChI InChI=1S/C34H26O8/c35-25-15-11-23(12-16-25)29-31(39)32(40)30(24-13-17-26(36)18-14-24)34(42-28(38)20-22-9-5-2-6-10-22)33(29)41-27(37)19-21-7-3-1-4-8-21/h1-18,35-36,39-40H,19-20H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo University of Agriculture Curated by ChEMBL					Assay Description Inhibition of human USP4 using Ub-AMC as substrate after 60 mins by fluorometric analysis				Bioorg Med Chem Lett 23: 4328-31 (2013) Article DOI: 10.1016/j.bmcl.2013.05.093 BindingDB Entry DOI: 10.7270/Q2T15528
					More data for this Ligand-Target Pair
Sentrin-specific protease 1 (Homo sapiens (Human))	BDBM50536673 (CHEMBL4587307) Show SMILES Oc1ccc(CC(=O)Oc2c(OC(=O)Cc3ccc(O)cc3)c(c(O)c(O)c2-c2ccc(O)cc2)-c2ccc(O)cc2)cc1 Show InChI InChI=1S/C34H26O10/c35-23-9-1-19(2-10-23)17-27(39)43-33-29(21-5-13-25(37)14-6-21)31(41)32(42)30(22-7-15-26(38)16-8-22)34(33)44-28(40)18-20-3-11-24(36)12-4-20/h1-16,35-38,41-42H,17-18H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo University of Agriculture Curated by ChEMBL					Assay Description Inhibition of recombinant human 6His-tagged SENP1 catalytic domain expressed in Escherichia coli preincubated for 15 mins followed by addition of SUM...				Bioorg Med Chem Lett 26: 4237-40 (2016) Article DOI: 10.1016/j.bmcl.2016.07.051 BindingDB Entry DOI: 10.7270/Q2SF30PB
					More data for this Ligand-Target Pair
Sentrin-specific protease 1 (Homo sapiens (Human))	BDBM50437693 (VIALININ A) Show SMILES Oc1ccc(cc1)-c1c(O)c(O)c(-c2ccc(O)cc2)c(OC(=O)Cc2ccccc2)c1OC(=O)Cc1ccccc1 Show InChI InChI=1S/C34H26O8/c35-25-15-11-23(12-16-25)29-31(39)32(40)30(24-13-17-26(36)18-14-24)34(42-28(38)20-22-9-5-2-6-10-22)33(29)41-27(37)19-21-7-3-1-4-8-21/h1-18,35-36,39-40H,19-20H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.64E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo University of Agriculture Curated by ChEMBL					Assay Description Inhibition of full-length recombinant human 6His-tagged SENP1 expressed in Escherichia coli BL21 (DE3) preincubated for 15 mins followed by addition ...				Bioorg Med Chem Lett 26: 4237-40 (2016) Article DOI: 10.1016/j.bmcl.2016.07.051 BindingDB Entry DOI: 10.7270/Q2SF30PB
					More data for this Ligand-Target Pair
Sentrin-specific protease 1 (Homo sapiens (Human))	BDBM50437693 (VIALININ A) Show SMILES Oc1ccc(cc1)-c1c(O)c(O)c(-c2ccc(O)cc2)c(OC(=O)Cc2ccccc2)c1OC(=O)Cc1ccccc1 Show InChI InChI=1S/C34H26O8/c35-25-15-11-23(12-16-25)29-31(39)32(40)30(24-13-17-26(36)18-14-24)34(42-28(38)20-22-9-5-2-6-10-22)33(29)41-27(37)19-21-7-3-1-4-8-21/h1-18,35-36,39-40H,19-20H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.89E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo University of Agriculture Curated by ChEMBL					Assay Description Inhibition of recombinant human 6His-tagged SENP1 catalytic domain expressed in Escherichia coli preincubated for 15 mins followed by addition of SUM...				Bioorg Med Chem Lett 26: 4237-40 (2016) Article DOI: 10.1016/j.bmcl.2016.07.051 BindingDB Entry DOI: 10.7270/Q2SF30PB
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50020333 (CHEMBL160653 | {2-[Butyryl-(2-methoxy-3-octadecylc...) Show SMILES CCCCCCCCCCCCCCCCCCNC(=O)OCC(COC(=O)N(CC[N+](C)(C)C)C(=O)OC)OC Show InChI InChI=1S/C31H61N3O7/c1-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-32-29(35)40-26-28(38-5)27-41-31(37)33(30(36)39-6)24-25-34(2,3)4/h28H,7-27H2,1-6H3/p+1	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Chemical Industries Ltd. Curated by ChEMBL					Assay Description Inhibition of rabbit platelet aggregation induced by platelet activating factor (PAF)				J Med Chem 32: 56-64 (1989) BindingDB Entry DOI: 10.7270/Q2ZP46QM
					More data for this Ligand-Target Pair
Sentrin-specific protease 1 (Homo sapiens (Human))	BDBM50536673 (CHEMBL4587307) Show SMILES Oc1ccc(CC(=O)Oc2c(OC(=O)Cc3ccc(O)cc3)c(c(O)c(O)c2-c2ccc(O)cc2)-c2ccc(O)cc2)cc1 Show InChI InChI=1S/C34H26O10/c35-23-9-1-19(2-10-23)17-27(39)43-33-29(21-5-13-25(37)14-6-21)31(41)32(42)30(22-7-15-26(38)16-8-22)34(33)44-28(40)18-20-3-11-24(36)12-4-20/h1-16,35-38,41-42H,17-18H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo University of Agriculture Curated by ChEMBL					Assay Description Inhibition of full-length recombinant human 6His-tagged SENP1 expressed in Escherichia coli BL21 (DE3) preincubated for 15 mins followed by addition ...				Bioorg Med Chem Lett 26: 4237-40 (2016) Article DOI: 10.1016/j.bmcl.2016.07.051 BindingDB Entry DOI: 10.7270/Q2SF30PB
					More data for this Ligand-Target Pair
Sentrin-specific protease 1 (Homo sapiens (Human))	BDBM50536672 (CHEMBL2012939) Show SMILES Cc1c(C)c(-c2ccc(O)cc2)c(O)c(O)c1-c1ccc(O)cc1 Show InChI InChI=1S/C20H18O4/c1-11-12(2)18(14-5-9-16(22)10-6-14)20(24)19(23)17(11)13-3-7-15(21)8-4-13/h3-10,21-24H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.71E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo University of Agriculture Curated by ChEMBL					Assay Description Inhibition of full-length recombinant human 6His-tagged SENP1 expressed in Escherichia coli BL21 (DE3) preincubated for 15 mins followed by addition ...				Bioorg Med Chem Lett 26: 4237-40 (2016) Article DOI: 10.1016/j.bmcl.2016.07.051 BindingDB Entry DOI: 10.7270/Q2SF30PB
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Homo sapiens (Human))	BDBM50437695 (CHEMBL1923233) Show SMILES CCC[C@H](NC(=O)C(=C\c1cccc(Br)n1)\C#N)c1ccccc1 |r| Show InChI InChI=1S/C19H18BrN3O/c1-2-7-17(14-8-4-3-5-9-14)23-19(24)15(13-21)12-16-10-6-11-18(20)22-16/h3-6,8-12,17H,2,7H2,1H3,(H,23,24)/b15-12+/t17-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo University of Agriculture Curated by ChEMBL					Assay Description Inhibition of UCH-L1 in human Z138 cells after 1 hr by immunoblotting analysis				Bioorg Med Chem Lett 23: 4328-31 (2013) Article DOI: 10.1016/j.bmcl.2013.05.093 BindingDB Entry DOI: 10.7270/Q2T15528
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 5 (Homo sapiens (Human))	BDBM50437695 (CHEMBL1923233) Show SMILES CCC[C@H](NC(=O)C(=C\c1cccc(Br)n1)\C#N)c1ccccc1 |r| Show InChI InChI=1S/C19H18BrN3O/c1-2-7-17(14-8-4-3-5-9-14)23-19(24)15(13-21)12-16-10-6-11-18(20)22-16/h3-6,8-12,17H,2,7H2,1H3,(H,23,24)/b15-12+/t17-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo University of Agriculture Curated by ChEMBL					Assay Description Inhibition of USP5 in human Z138 cells after 1 hr by immunoblotting analysis				Bioorg Med Chem Lett 23: 4328-31 (2013) Article DOI: 10.1016/j.bmcl.2013.05.093 BindingDB Entry DOI: 10.7270/Q2T15528
					More data for this Ligand-Target Pair
Probable ubiquitin carboxyl-terminal hydrolase FAF-X (Homo sapiens (Human))	BDBM50437695 (CHEMBL1923233) Show SMILES CCC[C@H](NC(=O)C(=C\c1cccc(Br)n1)\C#N)c1ccccc1 |r| Show InChI InChI=1S/C19H18BrN3O/c1-2-7-17(14-8-4-3-5-9-14)23-19(24)15(13-21)12-16-10-6-11-18(20)22-16/h3-6,8-12,17H,2,7H2,1H3,(H,23,24)/b15-12+/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo University of Agriculture Curated by ChEMBL					Assay Description Inhibition of USP9x in human Z138 cells after 1 hr by immunoblotting analysis				Bioorg Med Chem Lett 23: 4328-31 (2013) Article DOI: 10.1016/j.bmcl.2013.05.093 BindingDB Entry DOI: 10.7270/Q2T15528
					More data for this Ligand-Target Pair
Sentrin-specific protease 1 (Homo sapiens (Human))	BDBM50536672 (CHEMBL2012939) Show SMILES Cc1c(C)c(-c2ccc(O)cc2)c(O)c(O)c1-c1ccc(O)cc1 Show InChI InChI=1S/C20H18O4/c1-11-12(2)18(14-5-9-16(22)10-6-14)20(24)19(23)17(11)13-3-7-15(21)8-4-13/h3-10,21-24H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo University of Agriculture Curated by ChEMBL					Assay Description Inhibition of recombinant human 6His-tagged SENP1 catalytic domain expressed in Escherichia coli preincubated for 15 mins followed by addition of SUM...				Bioorg Med Chem Lett 26: 4237-40 (2016) Article DOI: 10.1016/j.bmcl.2016.07.051 BindingDB Entry DOI: 10.7270/Q2SF30PB
					More data for this Ligand-Target Pair
Sentrin-specific protease 1 (Homo sapiens (Human))	BDBM50536674 (CHEMBL4593579) Show SMILES OC1=C(C(=O)C(O)=C(C1=O)c1ccc(O)cc1)c1ccc(O)cc1 |c:6,t:1| Show InChI InChI=1S/C18H12O6/c19-11-5-1-9(2-6-11)13-15(21)17(23)14(18(24)16(13)22)10-3-7-12(20)8-4-10/h1-8,19-21,24H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.79E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo University of Agriculture Curated by ChEMBL					Assay Description Inhibition of full-length recombinant human 6His-tagged SENP1 expressed in Escherichia coli BL21 (DE3) preincubated for 15 mins followed by addition ...				Bioorg Med Chem Lett 26: 4237-40 (2016) Article DOI: 10.1016/j.bmcl.2016.07.051 BindingDB Entry DOI: 10.7270/Q2SF30PB
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 14 (Homo sapiens (Human))	BDBM50437694 (CHEMBL1410015) Show SMILES Cc1cc(C(=O)CN2CCCC2)c(C)n1-c1ccc(F)cc1 Show InChI InChI=1S/C18H21FN2O/c1-13-11-17(18(22)12-20-9-3-4-10-20)14(2)21(13)16-7-5-15(19)6-8-16/h5-8,11H,3-4,9-10,12H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tokyo University of Agriculture Curated by ChEMBL					Assay Description Inhibition of human USP14				Bioorg Med Chem Lett 23: 4328-31 (2013) Article DOI: 10.1016/j.bmcl.2013.05.093 BindingDB Entry DOI: 10.7270/Q2T15528
					More data for this Ligand-Target Pair				3D Structure (crystal)
Platelet-activating factor receptor (Cavia porcellus)	BDBM50020319 (1-{2-[Acetyl-(2-methoxy-3-octadecylcarbamoyloxy-pr...) Show SMILES CCCCCCCCCCCCCCCCCCNC(=O)OCC(COC(=O)N(CC[N+]1(C)CCCCC1)C(C)=O)OC Show InChI InChI=1S/C34H65N3O6/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-24-35-33(39)42-29-32(41-4)30-43-34(40)36(31(2)38)25-28-37(3)26-22-20-23-27-37/h32H,5-30H2,1-4H3/p+1	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Chemical Industries Ltd. Curated by ChEMBL					Assay Description Inhibition of rabbit platelet aggregation induced by platelet activating factor (PAF)				J Med Chem 32: 56-64 (1989) BindingDB Entry DOI: 10.7270/Q2ZP46QM
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50020320 (CHEMBL160910 | {2-[(2-Methoxy-3-octadecylcarbamoyl...) Show SMILES CCCCCCCCCCCCCCCCCCNC(=O)OCC(COC(=O)N(CC[N+](C)(C)C)C(=O)CC)OC Show InChI InChI=1S/C32H63N3O6/c1-7-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-33-31(37)40-27-29(39-6)28-41-32(38)34(30(36)8-2)25-26-35(3,4)5/h29H,7-28H2,1-6H3/p+1	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Chemical Industries Ltd. Curated by ChEMBL					Assay Description Inhibition of rabbit platelet aggregation induced by platelet activating factor (PAF)				J Med Chem 32: 56-64 (1989) BindingDB Entry DOI: 10.7270/Q2ZP46QM
					More data for this Ligand-Target Pair
Platelet-activating factor receptor (Cavia porcellus)	BDBM50020322 (CHEMBL350437 | {2-[Butyryl-(2-methoxy-3-octadecylc...) Show SMILES CCCCCCCCCCCCCCCCCCNC(=O)OCC(COC(=O)N(CC[N+](C)(C)C)C(=O)N(C)C)OC Show InChI InChI=1S/C32H64N4O6/c1-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-33-30(37)41-27-29(40-7)28-42-32(39)35(31(38)34(2)3)25-26-36(4,5)6/h29H,8-28H2,1-7H3/p+1	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Chemical Industries Ltd. Curated by ChEMBL					Assay Description Inhibition of rabbit platelet aggregation induced by platelet activating factor (PAF)				J Med Chem 32: 56-64 (1989) BindingDB Entry DOI: 10.7270/Q2ZP46QM
					More data for this Ligand-Target Pair

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