Compile Data Set for Download or QSAR

Found 117 hits with Last Name = 'zmudzki' and Initial = 'p'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM78940 (METHIOTHEPIN | MLS000859918 | Methiothepin mesylat...) Show SMILES CSc1ccc2Sc3ccccc3CC(N3CCN(C)CC3)c2c1 Show InChI InChI=1S/C20H24N2S2/c1-21-9-11-22(12-10-21)18-13-15-5-3-4-6-19(15)24-20-8-7-16(23-2)14-17(18)20/h3-8,14,18H,9-13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Jagiellonian University Medical College					Assay Description Binding experiments were conducted in 96-well microplates in a total volume of 250 μL of buffer (50 mM Tris-HCl pH 7.4, 10 mM MgCl2, 1 mM EDTA)....				Chem Biol Drug Des 89: 339-352 (2017) Article DOI: 10.1111/cbdd.12842 BindingDB Entry DOI: 10.7270/Q2PN94GQ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM152782 (1-[(2,5-dimethylphenoxy)propyl]-4-(2-methoxyphenyl...) Show SMILES Cl.COc1ccccc1N1CCN(CCCOc2cc(C)ccc2C)CC1 Show InChI InChI=1S/C22H30N2O2.ClH/c1-18-9-10-19(2)22(17-18)26-16-6-11-23-12-14-24(15-13-23)20-7-4-5-8-21(20)25-3;/h4-5,7-10,17H,6,11-16H2,1-3H3;1H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	<1	<-51.4	n/a	n/a	n/a	n/a	n/a	n/a	25
Jagiellonian University Medical College					Assay Description The composition of the assay buffers was as follows: for 5-HT1AR: 50 mM Tris¿HCl, 0.1 mM EDTA, 4 mM MgCl2, 10 lM pargyline, and 0.1% ascorbate; for 5...				Chem Biol Drug Des 85: 326-35 (2015) Article DOI: 10.1111/cbdd.12394 BindingDB Entry DOI: 10.7270/Q2DN43SZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM78940 (METHIOTHEPIN | MLS000859918 | Methiothepin mesylat...) Show SMILES CSc1ccc2Sc3ccccc3CC(N3CCN(C)CC3)c2c1 Show InChI InChI=1S/C20H24N2S2/c1-21-9-11-22(12-10-21)18-13-15-5-3-4-6-19(15)24-20-8-7-16(23-2)14-17(18)20/h3-8,14,18H,9-13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Jagiellonian University Medical College					Assay Description Binding experiments were conducted in 96-well microplates in a total volume of 250 μL of buffer (50 mM Tris-HCl pH 7.4, 10 mM MgCl2, 0.5 mM EDTA...				Chem Biol Drug Des 89: 339-352 (2017) Article DOI: 10.1111/cbdd.12842 BindingDB Entry DOI: 10.7270/Q2PN94GQ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM152784 (1-[(2,4,6-trimethylphenoxy)propyl]-4-(2-methoxyphe...) Show SMILES COc1ccccc1N1CCN(CCCOc2c(C)cc(C)cc2C)CC1 Show InChI InChI=1S/C23H32N2O2.ClH/c1-18-16-19(2)23(20(3)17-18)27-15-7-10-24-11-13-25(14-12-24)21-8-5-6-9-22(21)26-4;/h5-6,8-9,16-17H,7,10-15H2,1-4H3;1H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	<1	<-51.4	n/a	n/a	n/a	n/a	n/a	n/a	25
Jagiellonian University Medical College					Assay Description The composition of the assay buffers was as follows: for 5-HT1AR: 50 mM Tris¿HCl, 0.1 mM EDTA, 4 mM MgCl2, 10 lM pargyline, and 0.1% ascorbate; for 5...				Chem Biol Drug Des 85: 326-35 (2015) Article DOI: 10.1111/cbdd.12394 BindingDB Entry DOI: 10.7270/Q2DN43SZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM152786 (1-[(2-chloro-6-methylphenoxy)ethoxyethyl]-4-(2-met...) Show SMILES Cl.COc1ccccc1N1CCN(CCOCCOc2c(C)cccc2Cl)CC1 Show InChI InChI=1S/C22H29ClN2O3.ClH/c1-18-6-5-7-19(23)22(18)28-17-16-27-15-14-24-10-12-25(13-11-24)20-8-3-4-9-21(20)26-2;/h3-9H,10-17H2,1-2H3;1H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	<1	<-51.4	n/a	n/a	n/a	n/a	n/a	n/a	25
Jagiellonian University Medical College					Assay Description The composition of the assay buffers was as follows: for 5-HT1AR: 50 mM Tris¿HCl, 0.1 mM EDTA, 4 mM MgCl2, 10 lM pargyline, and 0.1% ascorbate; for 5...				Chem Biol Drug Des 85: 326-35 (2015) Article DOI: 10.1111/cbdd.12394 BindingDB Entry DOI: 10.7270/Q2DN43SZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Jagiellonian University Medical College					Assay Description Binding experiments were conducted in 96-well microplates in a total volume of 250 μL of buffer (50 mM Tris-HCl pH 7.4, 10 mM MgCl2, 0.5 mM EDTA...				Chem Biol Drug Des 89: 339-352 (2017) Article DOI: 10.1111/cbdd.12842 BindingDB Entry DOI: 10.7270/Q2PN94GQ
					More data for this Ligand-Target Pair				3D Structure (crystal)
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate | 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	3	-48.6	n/a	n/a	n/a	n/a	n/a	n/a	25
Jagiellonian University Medical College					Assay Description The composition of the assay buffers was as follows: for 5-HT1AR: 50 mM Tris¿HCl, 0.1 mM EDTA, 4 mM MgCl2, 10 lM pargyline, and 0.1% ascorbate; for 5...				Chem Biol Drug Des 85: 326-35 (2015) Article DOI: 10.1111/cbdd.12394 BindingDB Entry DOI: 10.7270/Q2DN43SZ
					More data for this Ligand-Target Pair				3D Structure (crystal)
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM22869 (6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...) Show SMILES CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 |c:8,15| Show InChI InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	4	-47.9	n/a	n/a	n/a	n/a	n/a	n/a	25
Jagiellonian University Medical College					Assay Description The composition of the assay buffers was as follows: for 5-HT1AR: 50 mM Tris¿HCl, 0.1 mM EDTA, 4 mM MgCl2, 10 lM pargyline, and 0.1% ascorbate; for 5...				Chem Biol Drug Des 85: 326-35 (2015) Article DOI: 10.1111/cbdd.12394 BindingDB Entry DOI: 10.7270/Q2DN43SZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM152783 (1-[(2,3,5-trimethylphenoxy)propyl]-4-(2-methoxyphe...) Show SMILES Cl.COc1ccccc1N1CCN(CCCOc2cc(C)cc(C)c2C)CC1 Show InChI InChI=1S/C23H32N2O2.ClH/c1-18-16-19(2)20(3)23(17-18)27-15-7-10-24-11-13-25(14-12-24)21-8-5-6-9-22(21)26-4;/h5-6,8-9,16-17H,7,10-15H2,1-4H3;1H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	6	-46.9	n/a	n/a	n/a	n/a	n/a	n/a	25
Jagiellonian University Medical College					Assay Description The composition of the assay buffers was as follows: for 5-HT1AR: 50 mM Tris¿HCl, 0.1 mM EDTA, 4 mM MgCl2, 10 lM pargyline, and 0.1% ascorbate; for 5...				Chem Biol Drug Des 85: 326-35 (2015) Article DOI: 10.1111/cbdd.12394 BindingDB Entry DOI: 10.7270/Q2DN43SZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50370986 (CHEMBL1203946) Show SMILES CCOc1nc2n(C)c(=O)n(C)c(=O)c2n1CCCCN1CCN(CC1)c1ccccc1OC Show InChI InChI=1S/C24H34N6O4/c1-5-34-23-25-21-20(22(31)27(3)24(32)26(21)2)30(23)13-9-8-12-28-14-16-29(17-15-28)18-10-6-7-11-19(18)33-4/h6-7,10-11H,5,8-9,12-17H2,1-4H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from rat brain 5HT1A receptor				Bioorg Med Chem 15: 5239-50 (2007) Article DOI: 10.1016/j.bmc.2007.05.017 BindingDB Entry DOI: 10.7270/Q22F7P87
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50001859 ((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...) Show SMILES O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1 Show InChI InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	12	-45.2	n/a	n/a	n/a	n/a	n/a	n/a	25
Jagiellonian University Medical College					Assay Description The composition of the assay buffers was as follows: for 5-HT1AR: 50 mM Tris¿HCl, 0.1 mM EDTA, 4 mM MgCl2, 10 lM pargyline, and 0.1% ascorbate; for 5...				Chem Biol Drug Des 85: 326-35 (2015) Article DOI: 10.1111/cbdd.12394 BindingDB Entry DOI: 10.7270/Q2DN43SZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50213571 (7-{4-[4-(3-chlorophenyl)-piperazin-1-yl]-butyl}-8-...) Show SMILES CCOc1nc2n(C)c(=O)n(C)c(=O)c2n1CCCCN1CCN(CC1)c1cccc(Cl)c1 Show InChI InChI=1S/C23H31ClN6O3/c1-4-33-22-25-20-19(21(31)27(3)23(32)26(20)2)30(22)11-6-5-10-28-12-14-29(15-13-28)18-9-7-8-17(24)16-18/h7-9,16H,4-6,10-15H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from rat brain 5HT1A receptor				Bioorg Med Chem 15: 5239-50 (2007) Article DOI: 10.1016/j.bmc.2007.05.017 BindingDB Entry DOI: 10.7270/Q22F7P87
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50213571 (7-{4-[4-(3-chlorophenyl)-piperazin-1-yl]-butyl}-8-...) Show SMILES CCOc1nc2n(C)c(=O)n(C)c(=O)c2n1CCCCN1CCN(CC1)c1cccc(Cl)c1 Show InChI InChI=1S/C23H31ClN6O3/c1-4-33-22-25-20-19(21(31)27(3)23(32)26(20)2)30(22)11-6-5-10-28-12-14-29(15-13-28)18-9-7-8-17(24)16-18/h7-9,16H,4-6,10-15H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from rat brain 5HT2A receptor				Bioorg Med Chem 15: 5239-50 (2007) Article DOI: 10.1016/j.bmc.2007.05.017 BindingDB Entry DOI: 10.7270/Q22F7P87
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50213587 (7-[4-(1,2,3,4-tetrahydroisoquinolin-2-yl)propyl]-8...) Show SMILES CCCOc1nc2n(C)c(=O)n(C)c(=O)c2n1CCCCN1CCN(CC1)c1cccc(Cl)c1 Show InChI InChI=1S/C24H33ClN6O3/c1-4-16-34-23-26-21-20(22(32)28(3)24(33)27(21)2)31(23)11-6-5-10-29-12-14-30(15-13-29)19-9-7-8-18(25)17-19/h7-9,17H,4-6,10-16H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from rat brain 5HT1A receptor				Bioorg Med Chem 15: 5239-50 (2007) Article DOI: 10.1016/j.bmc.2007.05.017 BindingDB Entry DOI: 10.7270/Q22F7P87
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM152781 (1-[(2-chloro-5-methylphenoxy)propyl]-4-(2-methoxyp...) Show SMILES Cl.COc1ccccc1N1CCN(CCCOc2cc(C)ccc2Cl)CC1 Show InChI InChI=1S/C21H27ClN2O2.ClH/c1-17-8-9-18(22)21(16-17)26-15-5-10-23-11-13-24(14-12-23)19-6-3-4-7-20(19)25-2;/h3-4,6-9,16H,5,10-15H2,1-2H3;1H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	15	-44.7	n/a	n/a	n/a	n/a	n/a	n/a	25
Jagiellonian University Medical College					Assay Description The composition of the assay buffers was as follows: for 5-HT1AR: 50 mM Tris¿HCl, 0.1 mM EDTA, 4 mM MgCl2, 10 lM pargyline, and 0.1% ascorbate; for 5...				Chem Biol Drug Des 85: 326-35 (2015) Article DOI: 10.1111/cbdd.12394 BindingDB Entry DOI: 10.7270/Q2DN43SZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM22869 (6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...) Show SMILES CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 |c:8,15| Show InChI InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	18	-44.2	n/a	n/a	n/a	n/a	n/a	n/a	25
Jagiellonian University Medical College					Assay Description The composition of the assay buffers was as follows: for 5-HT1AR: 50 mM Tris¿HCl, 0.1 mM EDTA, 4 mM MgCl2, 10 lM pargyline, and 0.1% ascorbate; for 5...				Chem Biol Drug Des 85: 326-35 (2015) Article DOI: 10.1111/cbdd.12394 BindingDB Entry DOI: 10.7270/Q2DN43SZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50213576 (7-{4-[4-(2-methoxyphenyl)-piperazin-1-yl]-butyl}-8...) Show SMILES CCCOc1nc2n(C)c(=O)n(C)c(=O)c2n1CCCCN1CCN(CC1)c1ccccc1OC Show InChI InChI=1S/C25H36N6O4/c1-5-18-35-24-26-22-21(23(32)28(3)25(33)27(22)2)31(24)13-9-8-12-29-14-16-30(17-15-29)19-10-6-7-11-20(19)34-4/h6-7,10-11H,5,8-9,12-18H2,1-4H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from rat brain 5HT1A receptor				Bioorg Med Chem 15: 5239-50 (2007) Article DOI: 10.1016/j.bmc.2007.05.017 BindingDB Entry DOI: 10.7270/Q22F7P87
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50213577 (7-{3-[4-(3-chlorophenyl)-piperazin-1-yl]-propyl}-8...) Show SMILES CCOc1nc2n(C)c(=O)n(C)c(=O)c2n1CCCN1CCN(CC1)c1cccc(Cl)c1 Show InChI InChI=1S/C22H29ClN6O3/c1-4-32-21-24-19-18(20(30)26(3)22(31)25(19)2)29(21)10-6-9-27-11-13-28(14-12-27)17-8-5-7-16(23)15-17/h5,7-8,15H,4,6,9-14H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from rat brain 5HT2A receptor				Bioorg Med Chem 15: 5239-50 (2007) Article DOI: 10.1016/j.bmc.2007.05.017 BindingDB Entry DOI: 10.7270/Q22F7P87
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM152782 (1-[(2,5-dimethylphenoxy)propyl]-4-(2-methoxyphenyl...) Show SMILES Cl.COc1ccccc1N1CCN(CCCOc2cc(C)ccc2C)CC1 Show InChI InChI=1S/C22H30N2O2.ClH/c1-18-9-10-19(2)22(17-18)26-16-6-11-23-12-14-24(15-13-23)20-7-4-5-8-21(20)25-3;/h4-5,7-10,17H,6,11-16H2,1-3H3;1H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	23	-43.6	n/a	n/a	n/a	n/a	n/a	n/a	25
Jagiellonian University Medical College					Assay Description The composition of the assay buffers was as follows: for 5-HT1AR: 50 mM Tris¿HCl, 0.1 mM EDTA, 4 mM MgCl2, 10 lM pargyline, and 0.1% ascorbate; for 5...				Chem Biol Drug Des 85: 326-35 (2015) Article DOI: 10.1111/cbdd.12394 BindingDB Entry DOI: 10.7270/Q2DN43SZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50213578 (7-{3-[4-(3-chlorophenyl)-piperazin-1-yl]-propyl}-8...) Show SMILES CCCOc1nc2n(C)c(=O)n(C)c(=O)c2n1CCCN1CCN(CC1)c1cccc(Cl)c1 Show InChI InChI=1S/C23H31ClN6O3/c1-4-15-33-22-25-20-19(21(31)27(3)23(32)26(20)2)30(22)10-6-9-28-11-13-29(14-12-28)18-8-5-7-17(24)16-18/h5,7-8,16H,4,6,9-15H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from rat brain 5HT2A receptor				Bioorg Med Chem 15: 5239-50 (2007) Article DOI: 10.1016/j.bmc.2007.05.017 BindingDB Entry DOI: 10.7270/Q22F7P87
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM152783 (1-[(2,3,5-trimethylphenoxy)propyl]-4-(2-methoxyphe...) Show SMILES Cl.COc1ccccc1N1CCN(CCCOc2cc(C)cc(C)c2C)CC1 Show InChI InChI=1S/C23H32N2O2.ClH/c1-18-16-19(2)20(3)23(17-18)27-15-7-10-24-11-13-25(14-12-24)21-8-5-6-9-22(21)26-4;/h5-6,8-9,16-17H,7,10-15H2,1-4H3;1H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	25	-43.4	n/a	n/a	n/a	n/a	n/a	n/a	25
Jagiellonian University Medical College					Assay Description The composition of the assay buffers was as follows: for 5-HT1AR: 50 mM Tris¿HCl, 0.1 mM EDTA, 4 mM MgCl2, 10 lM pargyline, and 0.1% ascorbate; for 5...				Chem Biol Drug Des 85: 326-35 (2015) Article DOI: 10.1111/cbdd.12394 BindingDB Entry DOI: 10.7270/Q2DN43SZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50213587 (7-[4-(1,2,3,4-tetrahydroisoquinolin-2-yl)propyl]-8...) Show SMILES CCCOc1nc2n(C)c(=O)n(C)c(=O)c2n1CCCCN1CCN(CC1)c1cccc(Cl)c1 Show InChI InChI=1S/C24H33ClN6O3/c1-4-16-34-23-26-21-20(22(32)28(3)24(33)27(21)2)31(23)11-6-5-10-29-12-14-30(15-13-29)19-9-7-8-18(25)17-19/h7-9,17H,4-6,10-16H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from rat brain 5HT2A receptor				Bioorg Med Chem 15: 5239-50 (2007) Article DOI: 10.1016/j.bmc.2007.05.017 BindingDB Entry DOI: 10.7270/Q22F7P87
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM152786 (1-[(2-chloro-6-methylphenoxy)ethoxyethyl]-4-(2-met...) Show SMILES Cl.COc1ccccc1N1CCN(CCOCCOc2c(C)cccc2Cl)CC1 Show InChI InChI=1S/C22H29ClN2O3.ClH/c1-18-6-5-7-19(23)22(18)28-17-16-27-15-14-24-10-12-25(13-11-24)20-8-3-4-9-21(20)26-2;/h3-9H,10-17H2,1-2H3;1H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	34	-42.6	n/a	n/a	n/a	n/a	n/a	n/a	25
Jagiellonian University Medical College					Assay Description The composition of the assay buffers was as follows: for 5-HT1AR: 50 mM Tris¿HCl, 0.1 mM EDTA, 4 mM MgCl2, 10 lM pargyline, and 0.1% ascorbate; for 5...				Chem Biol Drug Des 85: 326-35 (2015) Article DOI: 10.1111/cbdd.12394 BindingDB Entry DOI: 10.7270/Q2DN43SZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM152785 (1-[(2,6-dimethylphenoxy)ethoxyethyl]-4-(2-methoxyp...) Show SMILES COc1ccccc1N1CCN(CCOCCOc2c(C)cccc2C)CC1 Show InChI InChI=1S/C23H32N2O3.ClH/c1-19-7-6-8-20(2)23(19)28-18-17-27-16-15-24-11-13-25(14-12-24)21-9-4-5-10-22(21)26-3;/h4-10H,11-18H2,1-3H3;1H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	41	-42.2	n/a	n/a	n/a	n/a	n/a	n/a	25
Jagiellonian University Medical College					Assay Description The composition of the assay buffers was as follows: for 5-HT1AR: 50 mM Tris¿HCl, 0.1 mM EDTA, 4 mM MgCl2, 10 lM pargyline, and 0.1% ascorbate; for 5...				Chem Biol Drug Des 85: 326-35 (2015) Article DOI: 10.1111/cbdd.12394 BindingDB Entry DOI: 10.7270/Q2DN43SZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50213585 (7-[3-(4-phenylpiperazin-1-yl)-propyl]-8-propoxy-1,...) Show SMILES CCCOc1nc2n(C)c(=O)n(C)c(=O)c2n1CCCN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C23H32N6O3/c1-4-17-32-22-24-20-19(21(30)26(3)23(31)25(20)2)29(22)12-8-11-27-13-15-28(16-14-27)18-9-6-5-7-10-18/h5-7,9-10H,4,8,11-17H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from rat brain 5HT2A receptor				Bioorg Med Chem 15: 5239-50 (2007) Article DOI: 10.1016/j.bmc.2007.05.017 BindingDB Entry DOI: 10.7270/Q22F7P87
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50213571 (7-{4-[4-(3-chlorophenyl)-piperazin-1-yl]-butyl}-8-...) Show SMILES CCOc1nc2n(C)c(=O)n(C)c(=O)c2n1CCCCN1CCN(CC1)c1cccc(Cl)c1 Show InChI InChI=1S/C23H31ClN6O3/c1-4-33-22-25-20-19(21(31)27(3)23(32)26(20)2)30(22)11-6-5-10-28-12-14-29(15-13-28)18-9-7-8-17(24)16-18/h7-9,16H,4-6,10-15H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]5CT from 5HT7 receptor in Wistar rat hypothalamic membrane				Bioorg Med Chem 15: 5239-50 (2007) Article DOI: 10.1016/j.bmc.2007.05.017 BindingDB Entry DOI: 10.7270/Q22F7P87
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50370986 (CHEMBL1203946) Show SMILES CCOc1nc2n(C)c(=O)n(C)c(=O)c2n1CCCCN1CCN(CC1)c1ccccc1OC Show InChI InChI=1S/C24H34N6O4/c1-5-34-23-25-21-20(22(31)27(3)24(32)26(21)2)30(23)13-9-8-12-28-14-16-29(17-15-28)18-10-6-7-11-19(18)33-4/h6-7,10-11H,5,8-9,12-17H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	54	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]5CT from 5HT7 receptor in Wistar rat hypothalamic membrane				Bioorg Med Chem 15: 5239-50 (2007) Article DOI: 10.1016/j.bmc.2007.05.017 BindingDB Entry DOI: 10.7270/Q22F7P87
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50213581 (7-[4-(1,2,3,4-tetrahydroisoquinolin-2-yl)-butyl]-8...) Show SMILES CCCOc1nc2n(C)c(=O)n(C)c(=O)c2n1CCCCN1CCc2ccccc2C1 Show InChI InChI=1S/C23H31N5O3/c1-4-15-31-22-24-20-19(21(29)26(3)23(30)25(20)2)28(22)13-8-7-12-27-14-11-17-9-5-6-10-18(17)16-27/h5-6,9-10H,4,7-8,11-16H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]5CT from 5HT7 receptor in Wistar rat hypothalamic membrane				Bioorg Med Chem 15: 5239-50 (2007) Article DOI: 10.1016/j.bmc.2007.05.017 BindingDB Entry DOI: 10.7270/Q22F7P87
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50213588 (7-[4-(4-phenylpiperazin-1-yl)-butyl]-8-propoxy-1,3...) Show SMILES CCCOc1nc2n(C)c(=O)n(C)c(=O)c2n1CCCCN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C24H34N6O3/c1-4-18-33-23-25-21-20(22(31)27(3)24(32)26(21)2)30(23)13-9-8-12-28-14-16-29(17-15-28)19-10-6-5-7-11-19/h5-7,10-11H,4,8-9,12-18H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from rat brain 5HT2A receptor				Bioorg Med Chem 15: 5239-50 (2007) Article DOI: 10.1016/j.bmc.2007.05.017 BindingDB Entry DOI: 10.7270/Q22F7P87
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50213580 (7-{3-[4-(3-chlorophenyl)-piperazin-1-yl]-propyl}-1...) Show SMILES Cn1c2[nH]c(=O)n(CCCN3CCN(CC3)c3cccc(Cl)c3)c2c(=O)n(C)c1=O Show InChI InChI=1S/C20H25ClN6O3/c1-23-17-16(18(28)24(2)20(23)30)27(19(29)22-17)8-4-7-25-9-11-26(12-10-25)15-6-3-5-14(21)13-15/h3,5-6,13H,4,7-12H2,1-2H3,(H,22,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from rat brain 5HT2A receptor				Bioorg Med Chem 15: 5239-50 (2007) Article DOI: 10.1016/j.bmc.2007.05.017 BindingDB Entry DOI: 10.7270/Q22F7P87
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50213572 (7-{4-[4-(3-chlorophenyl)-piperazin-1-yl]-butyl}-1,...) Show SMILES Cn1c2[nH]c(=O)n(CCCCN3CCN(CC3)c3cccc(Cl)c3)c2c(=O)n(C)c1=O Show InChI InChI=1S/C21H27ClN6O3/c1-24-18-17(19(29)25(2)21(24)31)28(20(30)23-18)9-4-3-8-26-10-12-27(13-11-26)16-7-5-6-15(22)14-16/h5-7,14H,3-4,8-13H2,1-2H3,(H,23,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from rat brain 5HT2A receptor				Bioorg Med Chem 15: 5239-50 (2007) Article DOI: 10.1016/j.bmc.2007.05.017 BindingDB Entry DOI: 10.7270/Q22F7P87
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50213584 (7-[4-(4-phenylpiperazin-1-yl)-butyl]-8-ethoxy-1,3-...) Show SMILES CCOc1nc2n(C)c(=O)n(C)c(=O)c2n1CCCCN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C23H32N6O3/c1-4-32-22-24-20-19(21(30)26(3)23(31)25(20)2)29(22)13-9-8-12-27-14-16-28(17-15-27)18-10-6-5-7-11-18/h5-7,10-11H,4,8-9,12-17H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	67	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from rat brain 5HT1A receptor				Bioorg Med Chem 15: 5239-50 (2007) Article DOI: 10.1016/j.bmc.2007.05.017 BindingDB Entry DOI: 10.7270/Q22F7P87
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50213579 (7-{3-[4-(2-methoxyphenyl)-piperazin-1-yl]-propyl}-...) Show SMILES CCOc1nc2n(C)c(=O)n(C)c(=O)c2n1CCCN1CCN(CC1)c1ccccc1OC Show InChI InChI=1S/C23H32N6O4/c1-5-33-22-24-20-19(21(30)26(3)23(31)25(20)2)29(22)12-8-11-27-13-15-28(16-14-27)17-9-6-7-10-18(17)32-4/h6-7,9-10H,5,8,11-16H2,1-4H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	83	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from rat brain 5HT1A receptor				Bioorg Med Chem 15: 5239-50 (2007) Article DOI: 10.1016/j.bmc.2007.05.017 BindingDB Entry DOI: 10.7270/Q22F7P87
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50213570 (7-[4-(1,2,3,4-tetrahydroisoquinolin-2-yl)-butyl]-8...) Show SMILES CCOc1nc2n(C)c(=O)n(C)c(=O)c2n1CCCCN1CCc2ccccc2C1 Show InChI InChI=1S/C22H29N5O3/c1-4-30-21-23-19-18(20(28)25(3)22(29)24(19)2)27(21)13-8-7-12-26-14-11-16-9-5-6-10-17(16)15-26/h5-6,9-10H,4,7-8,11-15H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	83	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]5CT from 5HT7 receptor in Wistar rat hypothalamic membrane				Bioorg Med Chem 15: 5239-50 (2007) Article DOI: 10.1016/j.bmc.2007.05.017 BindingDB Entry DOI: 10.7270/Q22F7P87
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50213587 (7-[4-(1,2,3,4-tetrahydroisoquinolin-2-yl)propyl]-8...) Show SMILES CCCOc1nc2n(C)c(=O)n(C)c(=O)c2n1CCCCN1CCN(CC1)c1cccc(Cl)c1 Show InChI InChI=1S/C24H33ClN6O3/c1-4-16-34-23-26-21-20(22(32)28(3)24(33)27(21)2)31(23)11-6-5-10-29-12-14-30(15-13-29)19-9-7-8-18(25)17-19/h7-9,17H,4-6,10-16H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	125	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]5CT from 5HT7 receptor in Wistar rat hypothalamic membrane				Bioorg Med Chem 15: 5239-50 (2007) Article DOI: 10.1016/j.bmc.2007.05.017 BindingDB Entry DOI: 10.7270/Q22F7P87
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50213577 (7-{3-[4-(3-chlorophenyl)-piperazin-1-yl]-propyl}-8...) Show SMILES CCOc1nc2n(C)c(=O)n(C)c(=O)c2n1CCCN1CCN(CC1)c1cccc(Cl)c1 Show InChI InChI=1S/C22H29ClN6O3/c1-4-32-21-24-19-18(20(30)26(3)22(31)25(19)2)29(21)10-6-9-27-11-13-28(14-12-27)17-8-5-7-16(23)15-17/h5,7-8,15H,4,6,9-14H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]5CT from 5HT7 receptor in Wistar rat hypothalamic membrane				Bioorg Med Chem 15: 5239-50 (2007) Article DOI: 10.1016/j.bmc.2007.05.017 BindingDB Entry DOI: 10.7270/Q22F7P87
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50213588 (7-[4-(4-phenylpiperazin-1-yl)-butyl]-8-propoxy-1,3...) Show SMILES CCCOc1nc2n(C)c(=O)n(C)c(=O)c2n1CCCCN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C24H34N6O3/c1-4-18-33-23-25-21-20(22(31)27(3)24(32)26(21)2)30(23)13-9-8-12-28-14-16-29(17-15-28)19-10-6-5-7-11-19/h5-7,10-11H,4,8-9,12-18H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from rat brain 5HT1A receptor				Bioorg Med Chem 15: 5239-50 (2007) Article DOI: 10.1016/j.bmc.2007.05.017 BindingDB Entry DOI: 10.7270/Q22F7P87
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50213584 (7-[4-(4-phenylpiperazin-1-yl)-butyl]-8-ethoxy-1,3-...) Show SMILES CCOc1nc2n(C)c(=O)n(C)c(=O)c2n1CCCCN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C23H32N6O3/c1-4-32-22-24-20-19(21(30)26(3)23(31)25(20)2)29(22)13-9-8-12-27-14-16-28(17-15-27)18-10-6-5-7-11-18/h5-7,10-11H,4,8-9,12-17H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	131	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from rat brain 5HT2A receptor				Bioorg Med Chem 15: 5239-50 (2007) Article DOI: 10.1016/j.bmc.2007.05.017 BindingDB Entry DOI: 10.7270/Q22F7P87
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM22869 (6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...) Show SMILES CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 |c:8,15| Show InChI InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	143	-39.1	n/a	n/a	n/a	n/a	n/a	n/a	25
Jagiellonian University Medical College					Assay Description The composition of the assay buffers was as follows: for 5-HT1AR: 50 mM Tris¿HCl, 0.1 mM EDTA, 4 mM MgCl2, 10 lM pargyline, and 0.1% ascorbate; for 5...				Chem Biol Drug Des 85: 326-35 (2015) Article DOI: 10.1111/cbdd.12394 BindingDB Entry DOI: 10.7270/Q2DN43SZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50213576 (7-{4-[4-(2-methoxyphenyl)-piperazin-1-yl]-butyl}-8...) Show SMILES CCCOc1nc2n(C)c(=O)n(C)c(=O)c2n1CCCCN1CCN(CC1)c1ccccc1OC Show InChI InChI=1S/C25H36N6O4/c1-5-18-35-24-26-22-21(23(32)28(3)25(33)27(22)2)31(24)13-9-8-12-29-14-16-30(17-15-29)19-10-6-7-11-20(19)34-4/h6-7,10-11H,5,8-9,12-18H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from rat brain 5HT2A receptor				Bioorg Med Chem 15: 5239-50 (2007) Article DOI: 10.1016/j.bmc.2007.05.017 BindingDB Entry DOI: 10.7270/Q22F7P87
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM152785 (1-[(2,6-dimethylphenoxy)ethoxyethyl]-4-(2-methoxyp...) Show SMILES COc1ccccc1N1CCN(CCOCCOc2c(C)cccc2C)CC1 Show InChI InChI=1S/C23H32N2O3.ClH/c1-19-7-6-8-20(2)23(19)28-18-17-27-16-15-24-11-13-25(14-12-24)21-9-4-5-10-22(21)26-3;/h4-10H,11-18H2,1-3H3;1H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	156	-38.9	n/a	n/a	n/a	n/a	n/a	n/a	25
Jagiellonian University Medical College					Assay Description The composition of the assay buffers was as follows: for 5-HT1AR: 50 mM Tris¿HCl, 0.1 mM EDTA, 4 mM MgCl2, 10 lM pargyline, and 0.1% ascorbate; for 5...				Chem Biol Drug Des 85: 326-35 (2015) Article DOI: 10.1111/cbdd.12394 BindingDB Entry DOI: 10.7270/Q2DN43SZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM152784 (1-[(2,4,6-trimethylphenoxy)propyl]-4-(2-methoxyphe...) Show SMILES COc1ccccc1N1CCN(CCCOc2c(C)cc(C)cc2C)CC1 Show InChI InChI=1S/C23H32N2O2.ClH/c1-18-16-19(2)23(20(3)17-18)27-15-7-10-24-11-13-25(14-12-24)21-8-5-6-9-22(21)26-4;/h5-6,8-9,16-17H,7,10-15H2,1-4H3;1H	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	157	-38.8	n/a	n/a	n/a	n/a	n/a	n/a	25
Jagiellonian University Medical College					Assay Description The composition of the assay buffers was as follows: for 5-HT1AR: 50 mM Tris¿HCl, 0.1 mM EDTA, 4 mM MgCl2, 10 lM pargyline, and 0.1% ascorbate; for 5...				Chem Biol Drug Des 85: 326-35 (2015) Article DOI: 10.1111/cbdd.12394 BindingDB Entry DOI: 10.7270/Q2DN43SZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50213576 (7-{4-[4-(2-methoxyphenyl)-piperazin-1-yl]-butyl}-8...) Show SMILES CCCOc1nc2n(C)c(=O)n(C)c(=O)c2n1CCCCN1CCN(CC1)c1ccccc1OC Show InChI InChI=1S/C25H36N6O4/c1-5-18-35-24-26-22-21(23(32)28(3)25(33)27(22)2)31(24)13-9-8-12-29-14-16-30(17-15-29)19-10-6-7-11-20(19)34-4/h6-7,10-11H,5,8-9,12-18H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]5CT from 5HT7 receptor in Wistar rat hypothalamic membrane				Bioorg Med Chem 15: 5239-50 (2007) Article DOI: 10.1016/j.bmc.2007.05.017 BindingDB Entry DOI: 10.7270/Q22F7P87
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50213575 (7-[3-(4-phenylpiperazin-1-yl)-propyl]-8-ethoxy-1,3...) Show SMILES CCOc1nc2n(C)c(=O)n(C)c(=O)c2n1CCCN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C22H30N6O3/c1-4-31-21-23-19-18(20(29)25(3)22(30)24(19)2)28(21)12-8-11-26-13-15-27(16-14-26)17-9-6-5-7-10-17/h5-7,9-10H,4,8,11-16H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	176	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from rat brain 5HT2A receptor				Bioorg Med Chem 15: 5239-50 (2007) Article DOI: 10.1016/j.bmc.2007.05.017 BindingDB Entry DOI: 10.7270/Q22F7P87
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50010859 (CHEMBL11 | IMIPRAMINE HYDROCHLORIDE | IMIPRAMINE P...) Show SMILES CN(C)CCCN1c2ccccc2CCc2ccccc12 Show InChI InChI=1S/C19H24N2/c1-20(2)14-7-15-21-18-10-5-3-8-16(18)12-13-17-9-4-6-11-19(17)21/h3-6,8-11H,7,12-15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	190	-38.4	n/a	n/a	n/a	n/a	n/a	n/a	25
Jagiellonian University Medical College					Assay Description The composition of the assay buffers was as follows: for 5-HT1AR: 50 mM Tris¿HCl, 0.1 mM EDTA, 4 mM MgCl2, 10 lM pargyline, and 0.1% ascorbate; for 5...				Chem Biol Drug Des 85: 326-35 (2015) Article DOI: 10.1111/cbdd.12394 BindingDB Entry DOI: 10.7270/Q2DN43SZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50213577 (7-{3-[4-(3-chlorophenyl)-piperazin-1-yl]-propyl}-8...) Show SMILES CCOc1nc2n(C)c(=O)n(C)c(=O)c2n1CCCN1CCN(CC1)c1cccc(Cl)c1 Show InChI InChI=1S/C22H29ClN6O3/c1-4-32-21-24-19-18(20(30)26(3)22(31)25(19)2)29(21)10-6-9-27-11-13-28(14-12-27)17-8-5-7-16(23)15-17/h5,7-8,15H,4,6,9-14H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from rat brain 5HT1A receptor				Bioorg Med Chem 15: 5239-50 (2007) Article DOI: 10.1016/j.bmc.2007.05.017 BindingDB Entry DOI: 10.7270/Q22F7P87
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50213584 (7-[4-(4-phenylpiperazin-1-yl)-butyl]-8-ethoxy-1,3-...) Show SMILES CCOc1nc2n(C)c(=O)n(C)c(=O)c2n1CCCCN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C23H32N6O3/c1-4-32-22-24-20-19(21(30)26(3)23(31)25(20)2)29(22)13-9-8-12-27-14-16-28(17-15-27)18-10-6-5-7-11-18/h5-7,10-11H,4,8-9,12-17H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	197	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]5CT from 5HT7 receptor in Wistar rat hypothalamic membrane				Bioorg Med Chem 15: 5239-50 (2007) Article DOI: 10.1016/j.bmc.2007.05.017 BindingDB Entry DOI: 10.7270/Q22F7P87
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50213582 (7-[3-(4-phenylpiperazin-1-yl)-propyl]-1,3-dimethyl...) Show SMILES Cn1c2[nH]c(=O)n(CCCN3CCN(CC3)c3ccccc3)c2c(=O)n(C)c1=O Show InChI InChI=1S/C20H26N6O3/c1-22-17-16(18(27)23(2)20(22)29)26(19(28)21-17)10-6-9-24-11-13-25(14-12-24)15-7-4-3-5-8-15/h3-5,7-8H,6,9-14H2,1-2H3,(H,21,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from rat brain 5HT2A receptor				Bioorg Med Chem 15: 5239-50 (2007) Article DOI: 10.1016/j.bmc.2007.05.017 BindingDB Entry DOI: 10.7270/Q22F7P87
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50370986 (CHEMBL1203946) Show SMILES CCOc1nc2n(C)c(=O)n(C)c(=O)c2n1CCCCN1CCN(CC1)c1ccccc1OC Show InChI InChI=1S/C24H34N6O4/c1-5-34-23-25-21-20(22(31)27(3)24(32)26(21)2)30(23)13-9-8-12-28-14-16-29(17-15-28)18-10-6-7-11-19(18)33-4/h6-7,10-11H,5,8-9,12-17H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	253	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from rat brain 5HT2A receptor				Bioorg Med Chem 15: 5239-50 (2007) Article DOI: 10.1016/j.bmc.2007.05.017 BindingDB Entry DOI: 10.7270/Q22F7P87
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50213572 (7-{4-[4-(3-chlorophenyl)-piperazin-1-yl]-butyl}-1,...) Show SMILES Cn1c2[nH]c(=O)n(CCCCN3CCN(CC3)c3cccc(Cl)c3)c2c(=O)n(C)c1=O Show InChI InChI=1S/C21H27ClN6O3/c1-24-18-17(19(29)25(2)21(24)31)28(20(30)23-18)9-4-3-8-26-10-12-27(13-11-26)16-7-5-6-15(22)14-16/h5-7,14H,3-4,8-13H2,1-2H3,(H,23,30)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from rat brain 5HT1A receptor				Bioorg Med Chem 15: 5239-50 (2007) Article DOI: 10.1016/j.bmc.2007.05.017 BindingDB Entry DOI: 10.7270/Q22F7P87
					More data for this Ligand-Target Pair

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