Compile Data Set for Download or QSAR

Found 315 hits with Last Name = 'de candia' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50029090 (CHEMBL3343301) Show SMILES CC(C)N1CCC(CC1)C(=O)Nc1c(OCCCO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cccc1OCc1cc(on1)-c1ccc(Cl)s1 |r| Show InChI InChI=1S/C32H42ClN3O10S/c1-18(2)36-11-9-19(10-12-36)31(41)34-27-21(42-13-4-14-43-32-30(40)29(39)28(38)24(16-37)45-32)5-3-6-22(27)44-17-20-15-23(46-35-20)25-7-8-26(33)47-25/h3,5-8,15,18-19,24,28-30,32,37-40H,4,9-14,16-17H2,1-2H3,(H,34,41)/t24-,28-,29+,30-,32-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	0.0900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Consiglio Nazionale delle Ricerche Curated by ChEMBL					Assay Description Inhibition of human factor10a assessed as reduction in hydrolysis of chromogenic substrate S-2765 by Cheng-Prusoff equation analysis				J Med Chem 57: 8563-75 (2014) Article DOI: 10.1021/jm5010754 BindingDB Entry DOI: 10.7270/Q2GT5PSQ
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50029090 (CHEMBL3343301) Show SMILES CC(C)N1CCC(CC1)C(=O)Nc1c(OCCCO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cccc1OCc1cc(on1)-c1ccc(Cl)s1 |r| Show InChI InChI=1S/C32H42ClN3O10S/c1-18(2)36-11-9-19(10-12-36)31(41)34-27-21(42-13-4-14-43-32-30(40)29(39)28(38)24(16-37)45-32)5-3-6-22(27)44-17-20-15-23(46-35-20)25-7-8-26(33)47-25/h3,5-8,15,18-19,24,28-30,32,37-40H,4,9-14,16-17H2,1-2H3,(H,34,41)/t24-,28-,29+,30-,32-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	0.0960	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Consiglio Nazionale delle Ricerche Curated by ChEMBL					Assay Description Inhibition of bovine thrombin assessed as reduction in hydrolysis of chromogenic substrate S-2238 by Lineweaver-Burk analysis				J Med Chem 57: 8563-75 (2014) Article DOI: 10.1021/jm5010754 BindingDB Entry DOI: 10.7270/Q2GT5PSQ
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50029091 (CHEMBL3343299) Show SMILES CC(C)N1CCC(CC1)C(=O)Nc1ccccc1OCc1cc(on1)-c1ccc(Cl)s1 Show InChI InChI=1S/C23H26ClN3O3S/c1-15(2)27-11-9-16(10-12-27)23(28)25-18-5-3-4-6-19(18)29-14-17-13-20(30-26-17)21-7-8-22(24)31-21/h3-8,13,15-16H,9-12,14H2,1-2H3,(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Consiglio Nazionale delle Ricerche Curated by ChEMBL					Assay Description Inhibition of human factor10a assessed as reduction in hydrolysis of chromogenic substrate S-2765 by Lineweaver-Burk analysis				J Med Chem 57: 8563-75 (2014) Article DOI: 10.1021/jm5010754 BindingDB Entry DOI: 10.7270/Q2GT5PSQ
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50029095 (CHEMBL3343300) Show SMILES CC(C)N1CCC(CC1)C(=O)Nc1c(OCCCO[C@@H]2O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]2OC(C)=O)cccc1OCc1cc(on1)-c1ccc(Cl)s1 |r| Show InChI InChI=1S/C40H50ClN3O14S/c1-22(2)44-15-13-27(14-16-44)39(49)42-35-29(9-7-10-30(35)53-20-28-19-31(58-43-28)33-11-12-34(41)59-33)50-17-8-18-51-40-38(56-26(6)48)37(55-25(5)47)36(54-24(4)46)32(57-40)21-52-23(3)45/h7,9-12,19,22,27,32,36-38,40H,8,13-18,20-21H2,1-6H3,(H,42,49)/t32-,36-,37+,38-,40-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Consiglio Nazionale delle Ricerche Curated by ChEMBL					Assay Description Inhibition of human factor10a assessed as reduction in hydrolysis of chromogenic substrate S-2765 by Cheng-Prusoff equation analysis				J Med Chem 57: 8563-75 (2014) Article DOI: 10.1021/jm5010754 BindingDB Entry DOI: 10.7270/Q2GT5PSQ
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50029091 (CHEMBL3343299) Show SMILES CC(C)N1CCC(CC1)C(=O)Nc1ccccc1OCc1cc(on1)-c1ccc(Cl)s1 Show InChI InChI=1S/C23H26ClN3O3S/c1-15(2)27-11-9-16(10-12-27)23(28)25-18-5-3-4-6-19(18)29-14-17-13-20(30-26-17)21-7-8-22(24)31-21/h3-8,13,15-16H,9-12,14H2,1-2H3,(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Consiglio Nazionale delle Ricerche Curated by ChEMBL					Assay Description Inhibition of human factor10a assessed as reduction in hydrolysis of chromogenic substrate S-2765 by Cheng-Prusoff equation analysis				J Med Chem 57: 8563-75 (2014) Article DOI: 10.1021/jm5010754 BindingDB Entry DOI: 10.7270/Q2GT5PSQ
					More data for this Ligand-Target Pair
Cholinesterase (Equus caballus (Horse))	BDBM50210854 (CHEMBL3960040) Show SMILES Fc1cccc(CCn2c3CCCNC(=O)c3c3ccccc23)c1 Show InChI InChI=1S/C20H19FN2O/c21-15-6-3-5-14(13-15)10-12-23-17-8-2-1-7-16(17)19-18(23)9-4-11-22-20(19)24/h1-3,5-8,13H,4,9-12H2,(H,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari"A. Moro" Curated by ChEMBL					Assay Description Competitive inhibition of horse serum BChE in presence of varying levels of butyrylthiocholine iodide substrate by Lineweaver-burk plot method				Eur J Med Chem 125: 288-298 (2017) Article DOI: 10.1016/j.ejmech.2016.09.037 BindingDB Entry DOI: 10.7270/Q2G44S9D
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50029090 (CHEMBL3343301) Show SMILES CC(C)N1CCC(CC1)C(=O)Nc1c(OCCCO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cccc1OCc1cc(on1)-c1ccc(Cl)s1 |r| Show InChI InChI=1S/C32H42ClN3O10S/c1-18(2)36-11-9-19(10-12-36)31(41)34-27-21(42-13-4-14-43-32-30(40)29(39)28(38)24(16-37)45-32)5-3-6-22(27)44-17-20-15-23(46-35-20)25-7-8-26(33)47-25/h3,5-8,15,18-19,24,28-30,32,37-40H,4,9-14,16-17H2,1-2H3,(H,34,41)/t24-,28-,29+,30-,32-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	0.870	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Consiglio Nazionale delle Ricerche Curated by ChEMBL					Assay Description Inhibition of human factor10a assessed as reduction in hydrolysis of chromogenic substrate S-2765 by Lineweaver-Burk analysis				J Med Chem 57: 8563-75 (2014) Article DOI: 10.1021/jm5010754 BindingDB Entry DOI: 10.7270/Q2GT5PSQ
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50442068 (CHEMBL2441057) Show SMILES Fc1cccc(COc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)c1 Show InChI InChI=1S/C24H24FN3O2/c25-20-4-1-3-18(15-20)17-30-23-6-2-5-21(16-23)27-24(29)19-9-13-28(14-10-19)22-7-11-26-12-8-22/h1-8,11-12,15-16,19H,9-10,13-14,17H2,(H,27,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50442068 (CHEMBL2441057) Show SMILES Fc1cccc(COc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)c1 Show InChI InChI=1S/C24H24FN3O2/c25-20-4-1-3-18(15-20)17-30-23-6-2-5-21(16-23)27-24(29)19-9-13-28(14-10-19)22-7-11-26-12-8-22/h1-8,11-12,15-16,19H,9-10,13-14,17H2,(H,27,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50585934 (CHEMBL5082824) Show SMILES CN(CCCC(F)F)Cc1ccc(COc2ccc3c(CO)cc(=O)oc3c2)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Competitive inhibition of human recombinant MAO-B expressed in supersomes using kynuramine as substrate by Lineweaver-Burk plot analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01784 BindingDB Entry DOI: 10.7270/Q2BG2SWG
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50029091 (CHEMBL3343299) Show SMILES CC(C)N1CCC(CC1)C(=O)Nc1ccccc1OCc1cc(on1)-c1ccc(Cl)s1 Show InChI InChI=1S/C23H26ClN3O3S/c1-15(2)27-11-9-16(10-12-27)23(28)25-18-5-3-4-6-19(18)29-14-17-13-20(30-26-17)21-7-8-22(24)31-21/h3-8,13,15-16H,9-12,14H2,1-2H3,(H,25,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Consiglio Nazionale delle Ricerche Curated by ChEMBL					Assay Description Inhibition of bovine thrombin assessed as reduction in hydrolysis of chromogenic substrate S-2238 by Lineweaver-Burk analysis				J Med Chem 57: 8563-75 (2014) Article DOI: 10.1021/jm5010754 BindingDB Entry DOI: 10.7270/Q2GT5PSQ
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50442069 (CHEMBL2441037) Show SMILES COc1ccc(COc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)cc1OC Show InChI InChI=1S/C26H29N3O4/c1-31-24-7-6-19(16-25(24)32-2)18-33-23-5-3-4-21(17-23)28-26(30)20-10-14-29(15-11-20)22-8-12-27-13-9-22/h3-9,12-13,16-17,20H,10-11,14-15,18H2,1-2H3,(H,28,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50442073 (CHEMBL2441035) Show SMILES O=C(Nc1cccc(OCc2ccc3OCOc3c2)c1)C1CCN(CC1)c1ccncc1 Show InChI InChI=1S/C25H25N3O4/c29-25(19-8-12-28(13-9-19)21-6-10-26-11-7-21)27-20-2-1-3-22(15-20)30-16-18-4-5-23-24(14-18)32-17-31-23/h1-7,10-11,14-15,19H,8-9,12-13,16-17H2,(H,27,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50292901 (CHEMBL454373 | N-(3-((4'-(trifluoromethyl)biphenyl...) Show SMILES FC(F)(F)c1ccc(cc1)-c1ccc(COc2cccc(NC(=O)C3CCNCC3)c2)cc1 Show InChI InChI=1S/C26H25F3N2O2/c27-26(28,29)22-10-8-20(9-11-22)19-6-4-18(5-7-19)17-33-24-3-1-2-23(16-24)31-25(32)21-12-14-30-15-13-21/h1-11,16,21,30H,12-15,17H2,(H,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari Curated by ChEMBL					Assay Description Inhibition of human factor 10a by amydolitic assay				J Med Chem 52: 1018-28 (2009) Article DOI: 10.1021/jm801141f BindingDB Entry DOI: 10.7270/Q2BP02T6
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50442070 (CHEMBL2441054) Show SMILES Fc1cc(F)cc(COc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)c1 Show InChI InChI=1S/C24H23F2N3O2/c25-19-12-17(13-20(26)14-19)16-31-23-3-1-2-21(15-23)28-24(30)18-6-10-29(11-7-18)22-4-8-27-9-5-22/h1-5,8-9,12-15,18H,6-7,10-11,16H2,(H,28,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50442071 (CHEMBL2441055) Show SMILES Fc1ccccc1COc1cccc(NC(=O)C2CCN(CC2)c2ccncc2)c1 Show InChI InChI=1S/C24H24FN3O2/c25-23-7-2-1-4-19(23)17-30-22-6-3-5-20(16-22)27-24(29)18-10-14-28(15-11-18)21-8-12-26-13-9-21/h1-9,12-13,16,18H,10-11,14-15,17H2,(H,27,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	64	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50442074 (CHEMBL2441036) Show SMILES COc1cc(COc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)cc(OC)c1 Show InChI InChI=1S/C26H29N3O4/c1-31-24-14-19(15-25(17-24)32-2)18-33-23-5-3-4-21(16-23)28-26(30)20-8-12-29(13-9-20)22-6-10-27-11-7-22/h3-7,10-11,14-17,20H,8-9,12-13,18H2,1-2H3,(H,28,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	83	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Cholinesterase (Equus caballus (Horse))	BDBM50524749 (CHEMBL4538834) Show SMILES Cl.C(CCc1ccccc1)CN1CCCc2[nH]c3ccccc3c2C1 Show InChI InChI=1S/C22H26N2/c1-2-9-18(10-3-1)11-6-7-15-24-16-8-14-22-20(17-24)19-12-4-5-13-21(19)23-22/h1-5,9-10,12-13,23H,6-8,11,14-17H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	98	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari Aldo Moro Curated by ChEMBL					Assay Description Mixed type inhibition of equine serum BChE assessed as Ki using butyrylthiocholine as substrate preincubated for 20 mins followed by substrate additi...				Eur J Med Chem 177: 414-424 (2019) Article DOI: 10.1016/j.ejmech.2019.05.062 BindingDB Entry DOI: 10.7270/Q2RF5ZGP
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50029090 (CHEMBL3343301) Show SMILES CC(C)N1CCC(CC1)C(=O)Nc1c(OCCCO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cccc1OCc1cc(on1)-c1ccc(Cl)s1 |r| Show InChI InChI=1S/C32H42ClN3O10S/c1-18(2)36-11-9-19(10-12-36)31(41)34-27-21(42-13-4-14-43-32-30(40)29(39)28(38)24(16-37)45-32)5-3-6-22(27)44-17-20-15-23(46-35-20)25-7-8-26(33)47-25/h3,5-8,15,18-19,24,28-30,32,37-40H,4,9-14,16-17H2,1-2H3,(H,34,41)/t24-,28-,29+,30-,32-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Consiglio Nazionale delle Ricerche Curated by ChEMBL					Assay Description Inhibition of bovine thrombin assessed as reduction in hydrolysis of chromogenic substrate S-2238 by Cheng-Prusoff equation analysis				J Med Chem 57: 8563-75 (2014) Article DOI: 10.1021/jm5010754 BindingDB Entry DOI: 10.7270/Q2GT5PSQ
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50442075 (CHEMBL2441047) Show SMILES CS(=O)(=O)c1ccc(COc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)cc1 Show InChI InChI=1S/C25H27N3O4S/c1-33(30,31)24-7-5-19(6-8-24)18-32-23-4-2-3-21(17-23)27-25(29)20-11-15-28(16-12-20)22-9-13-26-14-10-22/h2-10,13-14,17,20H,11-12,15-16,18H2,1H3,(H,27,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	124	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50292898 (CHEMBL453387 | N-(3-((3',5'-difluorobiphenyl-4-yl)...) Show SMILES Fc1cc(F)cc(c1)-c1ccc(COc2cccc(NC(=O)C3CCNCC3)c2)cc1 Show InChI InChI=1S/C25H24F2N2O2/c26-21-12-20(13-22(27)14-21)18-6-4-17(5-7-18)16-31-24-3-1-2-23(15-24)29-25(30)19-8-10-28-11-9-19/h1-7,12-15,19,28H,8-11,16H2,(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari Curated by ChEMBL					Assay Description Inhibition of human factor 10a by amydolitic assay				J Med Chem 52: 1018-28 (2009) Article DOI: 10.1021/jm801141f BindingDB Entry DOI: 10.7270/Q2BP02T6
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50442079 (CHEMBL2441033) Show SMILES Fc1ccc(CCOc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)cc1 Show InChI InChI=1S/C25H26FN3O2/c26-21-6-4-19(5-7-21)12-17-31-24-3-1-2-22(18-24)28-25(30)20-10-15-29(16-11-20)23-8-13-27-14-9-23/h1-9,13-14,18,20H,10-12,15-17H2,(H,28,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	133	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of human factor 10a using Z-D-Arg-Gly-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50442093 (CHEMBL2441053) Show SMILES Clc1cccc(COc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)c1 Show InChI InChI=1S/C24H24ClN3O2/c25-20-4-1-3-18(15-20)17-30-23-6-2-5-21(16-23)27-24(29)19-9-13-28(14-10-19)22-7-11-26-12-8-22/h1-8,11-12,15-16,19H,9-10,13-14,17H2,(H,27,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	156	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50029095 (CHEMBL3343300) Show SMILES CC(C)N1CCC(CC1)C(=O)Nc1c(OCCCO[C@@H]2O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]2OC(C)=O)cccc1OCc1cc(on1)-c1ccc(Cl)s1 |r| Show InChI InChI=1S/C40H50ClN3O14S/c1-22(2)44-15-13-27(14-16-44)39(49)42-35-29(9-7-10-30(35)53-20-28-19-31(58-43-28)33-11-12-34(41)59-33)50-17-8-18-51-40-38(56-26(6)48)37(55-25(5)47)36(54-24(4)46)32(57-40)21-52-23(3)45/h7,9-12,19,22,27,32,36-38,40H,8,13-18,20-21H2,1-6H3,(H,42,49)/t32-,36-,37+,38-,40-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Consiglio Nazionale delle Ricerche Curated by ChEMBL					Assay Description Inhibition of bovine thrombin assessed as reduction in hydrolysis of chromogenic substrate S-2238 by Cheng-Prusoff equation analysis				J Med Chem 57: 8563-75 (2014) Article DOI: 10.1021/jm5010754 BindingDB Entry DOI: 10.7270/Q2GT5PSQ
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50292892 (CHEMBL490298 | N-{3-[(3'-fluoro-1,1'-biphenyl-4-yl...) Show SMILES Fc1cccc(c1)-c1ccc(COc2cccc(NC(=O)C3CCNCC3)c2)cc1 Show InChI InChI=1S/C25H25FN2O2/c26-22-4-1-3-21(15-22)19-9-7-18(8-10-19)17-30-24-6-2-5-23(16-24)28-25(29)20-11-13-27-14-12-20/h1-10,15-16,20,27H,11-14,17H2,(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	177	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari Curated by ChEMBL					Assay Description Inhibition of human factor 10a by amydolitic assay				J Med Chem 52: 1018-28 (2009) Article DOI: 10.1021/jm801141f BindingDB Entry DOI: 10.7270/Q2BP02T6
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50442072 (CHEMBL2441058) Show SMILES Fc1ccc(COc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)cc1 Show InChI InChI=1S/C24H24FN3O2/c25-20-6-4-18(5-7-20)17-30-23-3-1-2-21(16-23)27-24(29)19-10-14-28(15-11-19)22-8-12-26-13-9-22/h1-9,12-13,16,19H,10-11,14-15,17H2,(H,27,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	211	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50442094 (CHEMBL2441052) Show SMILES Clc1ccc(COc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)cc1 Show InChI InChI=1S/C24H24ClN3O2/c25-20-6-4-18(5-7-20)17-30-23-3-1-2-21(16-23)27-24(29)19-10-14-28(15-11-19)22-8-12-26-13-9-22/h1-9,12-13,16,19H,10-11,14-15,17H2,(H,27,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50292894 (CHEMBL490491 | N-(3-((2',4'-difluorobiphenyl-4-yl)...) Show SMILES Fc1ccc(c(F)c1)-c1ccc(COc2cccc(NC(=O)C3CCNCC3)c2)cc1 Show InChI InChI=1S/C25H24F2N2O2/c26-20-8-9-23(24(27)14-20)18-6-4-17(5-7-18)16-31-22-3-1-2-21(15-22)29-25(30)19-10-12-28-13-11-19/h1-9,14-15,19,28H,10-13,16H2,(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	512	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari Curated by ChEMBL					Assay Description Inhibition of human factor 10a by amydolitic assay				J Med Chem 52: 1018-28 (2009) Article DOI: 10.1021/jm801141f BindingDB Entry DOI: 10.7270/Q2BP02T6
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50292895 (CHEMBL489694 | N-(3-((2',3'-difluorobiphenyl-4-yl)...) Show SMILES Fc1cccc(c1F)-c1ccc(COc2cccc(NC(=O)C3CCNCC3)c2)cc1 Show InChI InChI=1S/C25H24F2N2O2/c26-23-6-2-5-22(24(23)27)18-9-7-17(8-10-18)16-31-21-4-1-3-20(15-21)29-25(30)19-11-13-28-14-12-19/h1-10,15,19,28H,11-14,16H2,(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	548	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari Curated by ChEMBL					Assay Description Inhibition of human factor 10a by amydolitic assay				J Med Chem 52: 1018-28 (2009) Article DOI: 10.1021/jm801141f BindingDB Entry DOI: 10.7270/Q2BP02T6
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50442069 (CHEMBL2441037) Show SMILES COc1ccc(COc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)cc1OC Show InChI InChI=1S/C26H29N3O4/c1-31-24-7-6-19(16-25(24)32-2)18-33-23-5-3-4-21(17-23)28-26(30)20-10-14-29(15-11-20)22-8-12-27-13-9-22/h3-9,12-13,16-17,20H,10-11,14-15,18H2,1-2H3,(H,28,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	606	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of human factor 10a using Z-D-Arg-Gly-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50292900 (CHEMBL508488 | N-(3-((3',4',5'-trifluorobiphenyl-4...) Show SMILES Fc1cc(cc(F)c1F)-c1ccc(COc2cccc(NC(=O)C3CCNCC3)c2)cc1 Show InChI InChI=1S/C25H23F3N2O2/c26-22-12-19(13-23(27)24(22)28)17-6-4-16(5-7-17)15-32-21-3-1-2-20(14-21)30-25(31)18-8-10-29-11-9-18/h1-7,12-14,18,29H,8-11,15H2,(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	666	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari Curated by ChEMBL					Assay Description Inhibition of human factor 10a by amydolitic assay				J Med Chem 52: 1018-28 (2009) Article DOI: 10.1021/jm801141f BindingDB Entry DOI: 10.7270/Q2BP02T6
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50292893 (CHEMBL524125 | N-(3-((2'-fluorobiphenyl-4-yl)metho...) Show SMILES Fc1ccccc1-c1ccc(COc2cccc(NC(=O)C3CCNCC3)c2)cc1 Show InChI InChI=1S/C25H25FN2O2/c26-24-7-2-1-6-23(24)19-10-8-18(9-11-19)17-30-22-5-3-4-21(16-22)28-25(29)20-12-14-27-15-13-20/h1-11,16,20,27H,12-15,17H2,(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	767	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari Curated by ChEMBL					Assay Description Inhibition of human factor 10a by amydolitic assay				J Med Chem 52: 1018-28 (2009) Article DOI: 10.1021/jm801141f BindingDB Entry DOI: 10.7270/Q2BP02T6
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50442078 (CHEMBL2441030) Show SMILES Fc1ccc(OCc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)cc1 Show InChI InChI=1S/C24H24FN3O2/c25-20-4-6-23(7-5-20)30-17-18-2-1-3-21(16-18)27-24(29)19-10-14-28(15-11-19)22-8-12-26-13-9-22/h1-9,12-13,16,19H,10-11,14-15,17H2,(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	774	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of human factor 10a using Z-D-Arg-Gly-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50292887 (CHEMBL491672 | N-{[3-(1,1'-biphenyl-4-yl)methoxy]p...) Show SMILES O=C(Nc1cccc(OCc2ccc(cc2)-c2ccccc2)c1)C1CCNCC1 Show InChI InChI=1S/C25H26N2O2/c28-25(22-13-15-26-16-14-22)27-23-7-4-8-24(17-23)29-18-19-9-11-21(12-10-19)20-5-2-1-3-6-20/h1-12,17,22,26H,13-16,18H2,(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari Curated by ChEMBL					Assay Description Inhibition of human factor 10a by amydolitic assay				J Med Chem 52: 1018-28 (2009) Article DOI: 10.1021/jm801141f BindingDB Entry DOI: 10.7270/Q2BP02T6
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50442072 (CHEMBL2441058) Show SMILES Fc1ccc(COc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)cc1 Show InChI InChI=1S/C24H24FN3O2/c25-20-6-4-18(5-7-20)17-30-23-3-1-2-21(16-23)27-24(29)19-10-14-28(15-11-19)22-8-12-26-13-9-22/h1-9,12-13,16,19H,10-11,14-15,17H2,(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of human factor 10a using Z-D-Arg-Gly-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50442081 (CHEMBL2441039) Show SMILES COc1cccc(COc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)c1 Show InChI InChI=1S/C25H27N3O3/c1-30-23-6-2-4-19(16-23)18-31-24-7-3-5-21(17-24)27-25(29)20-10-14-28(15-11-20)22-8-12-26-13-9-22/h2-9,12-13,16-17,20H,10-11,14-15,18H2,1H3,(H,27,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50292896 (CHEMBL508759 | N-(3-((2',5'-difluorobiphenyl-4-yl)...) Show SMILES Fc1ccc(F)c(c1)-c1ccc(COc2cccc(NC(=O)C3CCNCC3)c2)cc1 Show InChI InChI=1S/C25H24F2N2O2/c26-20-8-9-24(27)23(14-20)18-6-4-17(5-7-18)16-31-22-3-1-2-21(15-22)29-25(30)19-10-12-28-13-11-19/h1-9,14-15,19,28H,10-13,16H2,(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.27E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari Curated by ChEMBL					Assay Description Inhibition of human factor 10a by amydolitic assay				J Med Chem 52: 1018-28 (2009) Article DOI: 10.1021/jm801141f BindingDB Entry DOI: 10.7270/Q2BP02T6
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50442080 (CHEMBL2441040) Show SMILES COc1ccccc1COc1cccc(NC(=O)C2CCN(CC2)c2ccncc2)c1 Show InChI InChI=1S/C25H27N3O3/c1-30-24-8-3-2-5-20(24)18-31-23-7-4-6-21(17-23)27-25(29)19-11-15-28(16-12-19)22-9-13-26-14-10-22/h2-10,13-14,17,19H,11-12,15-16,18H2,1H3,(H,27,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50292897 (CHEMBL455203 | N-(3-((2',6'-difluorobiphenyl-4-yl)...) Show SMILES Fc1cccc(F)c1-c1ccc(COc2cccc(NC(=O)C3CCNCC3)c2)cc1 Show InChI InChI=1S/C25H24F2N2O2/c26-22-5-2-6-23(27)24(22)18-9-7-17(8-10-18)16-31-21-4-1-3-20(15-21)29-25(30)19-11-13-28-14-12-19/h1-10,15,19,28H,11-14,16H2,(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.45E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari Curated by ChEMBL					Assay Description Inhibition of human factor 10a by amydolitic assay				J Med Chem 52: 1018-28 (2009) Article DOI: 10.1021/jm801141f BindingDB Entry DOI: 10.7270/Q2BP02T6
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50292886 (CHEMBL491283 | N-(3-(biphenyl-4-ylmethoxy)phenyl)-...) Show SMILES NC(=N)N1CCCC(C1)C(=O)Nc1cccc(OCc2ccc(cc2)-c2ccccc2)c1 Show InChI InChI=1S/C26H28N4O2/c27-26(28)30-15-5-8-22(17-30)25(31)29-23-9-4-10-24(16-23)32-18-19-11-13-21(14-12-19)20-6-2-1-3-7-20/h1-4,6-7,9-14,16,22H,5,8,15,17-18H2,(H3,27,28)(H,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari Curated by ChEMBL					Assay Description Inhibition of human factor 10a by amydolitic assay				J Med Chem 52: 1018-28 (2009) Article DOI: 10.1021/jm801141f BindingDB Entry DOI: 10.7270/Q2BP02T6
					More data for this Ligand-Target Pair
Acetylcholinesterase (Homo sapiens (Human))	BDBM50585934 (CHEMBL5082824) Show SMILES CN(CCCC(F)F)Cc1ccc(COc2ccc3c(CO)cc(=O)oc3c2)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Mixed type inhibition of human AChE by Lineweaver-Burk plot analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01784 BindingDB Entry DOI: 10.7270/Q2BG2SWG
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50442082 (CHEMBL2441038) Show SMILES COc1ccc(COc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)cc1 Show InChI InChI=1S/C25H27N3O3/c1-30-23-7-5-19(6-8-23)18-31-24-4-2-3-21(17-24)27-25(29)20-11-15-28(16-12-20)22-9-13-26-14-10-22/h2-10,13-14,17,20H,11-12,15-16,18H2,1H3,(H,27,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.03E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50442092 (CHEMBL2441051) Show SMILES Brc1ccc(COc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)cc1 Show InChI InChI=1S/C24H24BrN3O2/c25-20-6-4-18(5-7-20)17-30-23-3-1-2-21(16-23)27-24(29)19-10-14-28(15-11-19)22-8-12-26-13-9-22/h1-9,12-13,16,19H,10-11,14-15,17H2,(H,27,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.03E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50442065 (CHEMBL2441032) Show SMILES Fc1cccc(CCOc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)c1 Show InChI InChI=1S/C25H26FN3O2/c26-21-4-1-3-19(17-21)11-16-31-24-6-2-5-22(18-24)28-25(30)20-9-14-29(15-10-20)23-7-12-27-13-8-23/h1-8,12-13,17-18,20H,9-11,14-16H2,(H,28,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.14E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of human factor 10a using Z-D-Arg-Gly-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50292884 (CHEMBL523099 | N-(3-(biphenyl-4-ylmethoxy)phenyl)p...) Show SMILES O=C(Nc1cccc(OCc2ccc(cc2)-c2ccccc2)c1)C1CCCNC1 Show InChI InChI=1S/C25H26N2O2/c28-25(22-8-5-15-26-17-22)27-23-9-4-10-24(16-23)29-18-19-11-13-21(14-12-19)20-6-2-1-3-7-20/h1-4,6-7,9-14,16,22,26H,5,8,15,17-18H2,(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari Curated by ChEMBL					Assay Description Inhibition of human factor 10a by amydolitic assay				J Med Chem 52: 1018-28 (2009) Article DOI: 10.1021/jm801141f BindingDB Entry DOI: 10.7270/Q2BP02T6
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50442086 (CHEMBL2441044) Show SMILES FC(F)(F)c1ccc(COc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)cc1 Show InChI InChI=1S/C25H24F3N3O2/c26-25(27,28)20-6-4-18(5-7-20)17-33-23-3-1-2-21(16-23)30-24(32)19-10-14-31(15-11-19)22-8-12-29-13-9-22/h1-9,12-13,16,19H,10-11,14-15,17H2,(H,30,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50442073 (CHEMBL2441035) Show SMILES O=C(Nc1cccc(OCc2ccc3OCOc3c2)c1)C1CCN(CC1)c1ccncc1 Show InChI InChI=1S/C25H25N3O4/c29-25(19-8-12-28(13-9-19)21-6-10-26-11-7-21)27-20-2-1-3-22(15-20)30-16-18-4-5-23-24(14-18)32-17-31-23/h1-7,10-11,14-15,19H,8-9,12-13,16-17H2,(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.72E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of human factor 10a using Z-D-Arg-Gly-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Prothrombin (Bos taurus (Bovine))	BDBM50442076 (CHEMBL2441029) Show SMILES Fc1ccc(CCc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)cc1 Show InChI InChI=1S/C25H26FN3O/c26-22-8-6-19(7-9-22)4-5-20-2-1-3-23(18-20)28-25(30)21-12-16-29(17-13-21)24-10-14-27-15-11-24/h1-3,6-11,14-15,18,21H,4-5,12-13,16-17H2,(H,28,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.72E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50442067 (CHEMBL2441027) Show SMILES Fc1cccc(COc2cccc(NCC3CCN(CC3)c3ccncc3)c2)c1 Show InChI InChI=1S/C24H26FN3O/c25-21-4-1-3-20(15-21)18-29-24-6-2-5-22(16-24)27-17-19-9-13-28(14-10-19)23-7-11-26-12-8-23/h1-8,11-12,15-16,19,27H,9-10,13-14,17-18H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.83E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari "Aldo Moro" Curated by ChEMBL					Assay Description Inhibition of human factor 10a using Z-D-Arg-Gly-Arg-p-NA as substrate by chromogenic assay				J Med Chem 56: 8696-711 (2013) Article DOI: 10.1021/jm401169a BindingDB Entry DOI: 10.7270/Q2SN0BDT
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50292891 (CHEMBL490297 | N-(3-((4'-fluorobiphenyl-4-yl)metho...) Show SMILES Fc1ccc(cc1)-c1ccc(COc2cccc(NC(=O)C3CCNCC3)c2)cc1 Show InChI InChI=1S/C25H25FN2O2/c26-22-10-8-20(9-11-22)19-6-4-18(5-7-19)17-30-24-3-1-2-23(16-24)28-25(29)21-12-14-27-15-13-21/h1-11,16,21,27H,12-15,17H2,(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.87E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bari Curated by ChEMBL					Assay Description Inhibition of human factor 10a by amydolitic assay				J Med Chem 52: 1018-28 (2009) Article DOI: 10.1021/jm801141f BindingDB Entry DOI: 10.7270/Q2BP02T6
					More data for this Ligand-Target Pair

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