Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50067584 ((S)-2-{[5-((R)-2-Amino-3-mercapto-propylamino)-bip...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of mammalian protein farnesyltransferase | J Med Chem 47: 432-45 (2004) Article DOI: 10.1021/jm030236o BindingDB Entry DOI: 10.7270/Q2TQ60Z4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM16182 ((2S)-2-[(4-{[(1H-imidazol-4-ylmethyl)amino]methyl}...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.860 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of mammalian protein farnesyltransferase | J Med Chem 47: 432-45 (2004) Article DOI: 10.1021/jm030236o BindingDB Entry DOI: 10.7270/Q2TQ60Z4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50067584 ((S)-2-{[5-((R)-2-Amino-3-mercapto-propylamino)-bip...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei protein farnesyltransferase | J Med Chem 47: 432-45 (2004) Article DOI: 10.1021/jm030236o BindingDB Entry DOI: 10.7270/Q2TQ60Z4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM16182 ((2S)-2-[(4-{[(1H-imidazol-4-ylmethyl)amino]methyl}...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei protein farnesyltransferase | J Med Chem 47: 432-45 (2004) Article DOI: 10.1021/jm030236o BindingDB Entry DOI: 10.7270/Q2TQ60Z4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50138762 ((S)-2-[(5-{[Bis-(1H-imidazol-4-ylmethyl)-amino]-me...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei protein farnesyltransferase | J Med Chem 47: 432-45 (2004) Article DOI: 10.1021/jm030236o BindingDB Entry DOI: 10.7270/Q2TQ60Z4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50138763 ((S)-2-({2'-Methyl-5-[2-(3-methyl-3H-imidazol-4-yl)...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei protein farnesyltransferase | J Med Chem 47: 432-45 (2004) Article DOI: 10.1021/jm030236o BindingDB Entry DOI: 10.7270/Q2TQ60Z4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50097810 ((S)-2-({5-[(3-Biphenyl-4-ylmethyl-3H-imidazol-4-yl...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei protein farnesyltransferase at 50 nM | J Med Chem 47: 432-45 (2004) Article DOI: 10.1021/jm030236o BindingDB Entry DOI: 10.7270/Q2TQ60Z4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cycloartenol-C-24-methyltransferase (Arabidopsis thaliana) | BDBM50409741 (CHEMBL2069130) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Cardiff University Curated by ChEMBL | Assay Description In vitro inhibitory concentration against L. major Sterol 24-C-methyltransferase (24-SMT) | J Med Chem 46: 4714-27 (2003) Article DOI: 10.1021/jm021114j BindingDB Entry DOI: 10.7270/Q2K073PR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human)) | BDBM50138764 ((S)-2-{[5-((R)-2-Amino-3-mercapto-propylamino)-bip...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of Trypanosoma brucei protein farnesyltransferase | J Med Chem 47: 432-45 (2004) Article DOI: 10.1021/jm030236o BindingDB Entry DOI: 10.7270/Q2TQ60Z4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cycloartenol-C-24-methyltransferase (Arabidopsis thaliana) | BDBM50134737 ((3S,10S,13S,17S)-17-(1-Hydroxy-1-piperidin-3-yl-et...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Cardiff University Curated by ChEMBL | Assay Description In vitro inhibitory concentration against L. major Sterol 24-C-methyltransferase (24-SMT) | J Med Chem 46: 4714-27 (2003) Article DOI: 10.1021/jm021114j BindingDB Entry DOI: 10.7270/Q2K073PR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cycloartenol-C-24-methyltransferase (Arabidopsis thaliana) | BDBM50134726 (1-[(3S,10S,13S,17S)-3-(tert-Butyl-dimethyl-silanyl...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Cardiff University Curated by ChEMBL | Assay Description In vitro inhibitory concentration against L. major Sterol 24-C-methyltransferase (24-SMT) | J Med Chem 46: 4714-27 (2003) Article DOI: 10.1021/jm021114j BindingDB Entry DOI: 10.7270/Q2K073PR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cycloartenol-C-24-methyltransferase (Arabidopsis thaliana) | BDBM50409742 (CHEMBL2069129) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.22E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Cardiff University Curated by ChEMBL | Assay Description In vitro inhibitory concentration against L. major Sterol 24-C-methyltransferase (24-SMT) | J Med Chem 46: 4714-27 (2003) Article DOI: 10.1021/jm021114j BindingDB Entry DOI: 10.7270/Q2K073PR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cycloartenol-C-24-methyltransferase (Arabidopsis thaliana) | BDBM50134736 (1-{2-[1-Hydroxy-1-((3S,10S,13S,17S)-3-hydroxy-10,1...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.29E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Cardiff University Curated by ChEMBL | Assay Description In vitro inhibitory concentration against L. major Sterol 24-C-methyltransferase (24-SMT) | J Med Chem 46: 4714-27 (2003) Article DOI: 10.1021/jm021114j BindingDB Entry DOI: 10.7270/Q2K073PR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cycloartenol-C-24-methyltransferase (Arabidopsis thaliana) | BDBM50134738 ((3S,10S,13S,17S)-17-(1-Hydroxy-1-pyridin-3-yl-ethy...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.85E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Cardiff University Curated by ChEMBL | Assay Description In vitro inhibitory concentration against L. major Sterol 24-C-methyltransferase (24-SMT) | J Med Chem 46: 4714-27 (2003) Article DOI: 10.1021/jm021114j BindingDB Entry DOI: 10.7270/Q2K073PR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cycloartenol-C-24-methyltransferase (Arabidopsis thaliana) | BDBM50134731 (1-{3-[1-Hydroxy-1-((3S,10S,13S,17S)-3-hydroxy-10,1...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Cardiff University Curated by ChEMBL | Assay Description In vitro inhibitory concentration against L. major Sterol 24-C-methyltransferase (24-SMT) | J Med Chem 46: 4714-27 (2003) Article DOI: 10.1021/jm021114j BindingDB Entry DOI: 10.7270/Q2K073PR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cycloartenol-C-24-methyltransferase (Arabidopsis thaliana) | BDBM50134724 (1-(2-{1-[(3S,10S,13S,17S)-3-(tert-Butyl-dimethyl-s...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Cardiff University Curated by ChEMBL | Assay Description In vitro inhibitory concentration against L. major Sterol 24-C-methyltransferase (24-SMT) | J Med Chem 46: 4714-27 (2003) Article DOI: 10.1021/jm021114j BindingDB Entry DOI: 10.7270/Q2K073PR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cycloartenol-C-24-methyltransferase (Arabidopsis thaliana) | BDBM50134734 (1-[(3S,10S,17S)-3-(tert-Butyl-dimethyl-silanyloxy)...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Cardiff University Curated by ChEMBL | Assay Description In vitro inhibitory concentration against L. major Sterol 24-C-methyltransferase (24-SMT) | J Med Chem 46: 4714-27 (2003) Article DOI: 10.1021/jm021114j BindingDB Entry DOI: 10.7270/Q2K073PR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cycloartenol-C-24-methyltransferase (Arabidopsis thaliana) | BDBM50134729 (1-[(3S,10S,13S,17S)-3-(tert-Butyl-dimethyl-silanyl...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Cardiff University Curated by ChEMBL | Assay Description In vitro inhibitory concentration against L. major Sterol 24-C-methyltransferase (24-SMT) | J Med Chem 46: 4714-27 (2003) Article DOI: 10.1021/jm021114j BindingDB Entry DOI: 10.7270/Q2K073PR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cycloartenol-C-24-methyltransferase (Arabidopsis thaliana) | BDBM50134733 (1-[(3S,10S,13S,17S)-3-(tert-Butyl-dimethyl-silanyl...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Cardiff University Curated by ChEMBL | Assay Description In vitro inhibitory concentration against L. major Sterol 24-C-methyltransferase (24-SMT) | J Med Chem 46: 4714-27 (2003) Article DOI: 10.1021/jm021114j BindingDB Entry DOI: 10.7270/Q2K073PR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cycloartenol-C-24-methyltransferase (Arabidopsis thaliana) | BDBM50134730 (1-(3-{1-[(3S,10S,13S,17S)-3-(tert-Butyl-dimethyl-s...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Cardiff University Curated by ChEMBL | Assay Description In vitro inhibitory concentration against L. major Sterol 24-C-methyltransferase (24-SMT) | J Med Chem 46: 4714-27 (2003) Article DOI: 10.1021/jm021114j BindingDB Entry DOI: 10.7270/Q2K073PR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cycloartenol-C-24-methyltransferase (Arabidopsis thaliana) | BDBM50134723 ((3S,10S,13S,17S)-17-(1-Hydroxy-1-pyridin-4-yl-ethy...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Cardiff University Curated by ChEMBL | Assay Description In vitro inhibitory concentration against L. major Sterol 24-C-methyltransferase (24-SMT) | J Med Chem 46: 4714-27 (2003) Article DOI: 10.1021/jm021114j BindingDB Entry DOI: 10.7270/Q2K073PR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cycloartenol-C-24-methyltransferase (Arabidopsis thaliana) | BDBM50134727 (1-[(3S,10S,13S,17S)-3-(tert-Butyl-dimethyl-silanyl...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Cardiff University Curated by ChEMBL | Assay Description In vitro inhibitory concentration against L. major Sterol 24-C-methyltransferase (24-SMT) | J Med Chem 46: 4714-27 (2003) Article DOI: 10.1021/jm021114j BindingDB Entry DOI: 10.7270/Q2K073PR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cycloartenol-C-24-methyltransferase (Arabidopsis thaliana) | BDBM50134728 ((3S,10S,13S,17S)-17-[1-(3-Chloro-pyridin-4-yl)-1-h...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Cardiff University Curated by ChEMBL | Assay Description In vitro inhibitory concentration against L. major Sterol 24-C-methyltransferase (24-SMT) | J Med Chem 46: 4714-27 (2003) Article DOI: 10.1021/jm021114j BindingDB Entry DOI: 10.7270/Q2K073PR | |||||||||||
More data for this Ligand-Target Pair |