Found 6 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
5-hydroxytryptamine receptor 1D
(Sus scrofa) | BDBM50213961
(CHEMBL53739)Show InChI InChI=1S/C16H19N5/c1-20-6-4-12(5-7-20)15-9-17-16-3-2-13(8-14(15)16)21-10-18-19-11-21/h2-3,8-12,17H,4-7H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Compound was tested for its ability to displace [3H]-5-HT binding to 5-hydroxytryptamine 1D receptor recognition sites in pig caudate membranes |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2SX6GDH |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Sus scrofa) | BDBM50213961
(CHEMBL53739)Show InChI InChI=1S/C16H19N5/c1-20-6-4-12(5-7-20)15-9-17-16-3-2-13(8-14(15)16)21-10-18-19-11-21/h2-3,8-12,17H,4-7H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Compound was tested for its ability to displace [3H]-5-HT binding to 5-hydroxytryptamine 1D receptor recognition sites in pig caudate membranes |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2SX6GDH |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50213961
(CHEMBL53739)Show InChI InChI=1S/C16H19N5/c1-20-6-4-12(5-7-20)15-9-17-16-3-2-13(8-14(15)16)21-10-18-19-11-21/h2-3,8-12,17H,4-7H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | n/a | n/a | 95 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Compound was tested for its ability to displace [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor in pig cortex |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2SX6GDH |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A/3B
(Rattus norvegicus-RAT) | BDBM50213961
(CHEMBL53739)Show InChI InChI=1S/C16H19N5/c1-20-6-4-12(5-7-20)15-9-17-16-3-2-13(8-14(15)16)21-10-18-19-11-21/h2-3,8-12,17H,4-7H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Compound was tested for its ability to displace [3H]-Q-ICS 205-930 from 5-hydroxytryptamine 3 receptor in rat cortex homogenates |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2SX6GDH |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Rattus norvegicus (rat)) | BDBM50213961
(CHEMBL53739)Show InChI InChI=1S/C16H19N5/c1-20-6-4-12(5-7-20)15-9-17-16-3-2-13(8-14(15)16)21-10-18-19-11-21/h2-3,8-12,17H,4-7H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Compound was tested for its ability to displace [3H]DOB from 5-hydroxytryptamine 2A receptor in rat cortex homogenates |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2SX6GDH |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50213961
(CHEMBL53739)Show InChI InChI=1S/C16H19N5/c1-20-6-4-12(5-7-20)15-9-17-16-3-2-13(8-14(15)16)21-10-18-19-11-21/h2-3,8-12,17H,4-7H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Compound was tested for its ability to displace [3H]mesulergine from 5-hydroxytryptamine 2C receptor in pig cortex |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2SX6GDH |
More data for this Ligand-Target Pair | |