Found 19 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50174412
(9-Methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole ...)Show InChI InChI=1S/C18H16N2O/c1-10-15-9-19-7-6-13(15)11(2)18-17(10)14-8-12(21-3)4-5-16(14)20-18/h4-9,20H,1-3H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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| Article PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113
Curated by ChEMBL
| Assay Description Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus |
J Med Chem 48: 6194-201 (2005)
Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR |
More data for this Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50174412
(9-Methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole ...)Show InChI InChI=1S/C18H16N2O/c1-10-15-9-19-7-6-13(15)11(2)18-17(10)14-8-12(21-3)4-5-16(14)20-18/h4-9,20H,1-3H3 | PDB
UniProtKB/SwissProt
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| Article PubMed
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113
Curated by ChEMBL
| Assay Description Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus |
J Med Chem 48: 6194-201 (2005)
Article DOI: 10.1021/jm050231m BindingDB Entry DOI: 10.7270/Q2B27TTR |
More data for this Ligand-Target Pair | |
Neutrophil cytosol factor 1 [S99G]
(Homo sapiens (Human)) | BDBM50174412
(9-Methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole ...)Show InChI InChI=1S/C18H16N2O/c1-10-15-9-19-7-6-13(15)11(2)18-17(10)14-8-12(21-3)4-5-16(14)20-18/h4-9,20H,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
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| PCBioAssay
| n/a | n/a | 1.78E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Molecular Libraries Screening Center
Curated by PubChem BioAssay
| Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Susan Smith, Emory Univers... |
PubChem Bioassay (2008)
BindingDB Entry DOI: 10.7270/Q2M90723 |
More data for this Ligand-Target Pair | |
DNA damage-inducible transcript 3 protein
(Mus musculus) | BDBM50174412
(9-Methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole ...)Show InChI InChI=1S/C18H16N2O/c1-10-15-9-19-7-6-13(15)11(2)18-17(10)14-8-12(21-3)4-5-16(14)20-18/h4-9,20H,1-3H3 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
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Similars
| PCBioAssay
| n/a | n/a | 5.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Molecular Libraries Screening Center
Curated by PubChem BioAssay
| Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer... |
PubChem Bioassay (2011)
BindingDB Entry DOI: 10.7270/Q28C9TQN |
More data for this Ligand-Target Pair | |
DNA damage-inducible transcript 3 protein
(Mus musculus) | BDBM50174412
(9-Methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole ...)Show InChI InChI=1S/C18H16N2O/c1-10-15-9-19-7-6-13(15)11(2)18-17(10)14-8-12(21-3)4-5-16(14)20-18/h4-9,20H,1-3H3 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
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| PCBioAssay
| n/a | n/a | 5.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Molecular Libraries Screening Center
Curated by PubChem BioAssay
| Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer... |
PubChem Bioassay (2010)
BindingDB Entry DOI: 10.7270/Q2PC30VZ |
More data for this Ligand-Target Pair | |
X-box-binding protein 1
(Homo sapiens (Human)) | BDBM50174412
(9-Methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole ...)Show InChI InChI=1S/C18H16N2O/c1-10-15-9-19-7-6-13(15)11(2)18-17(10)14-8-12(21-3)4-5-16(14)20-18/h4-9,20H,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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| PCBioAssay
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Molecular Libraries Screening Center
Curated by PubChem BioAssay
| Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer... |
PubChem Bioassay (2011)
BindingDB Entry DOI: 10.7270/Q2NK3CGB |
More data for this Ligand-Target Pair | |
DNA repair protein RAD51 homolog 1
(Homo sapiens (Human)) | BDBM50174412
(9-Methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole ...)Show InChI InChI=1S/C18H16N2O/c1-10-15-9-19-7-6-13(15)11(2)18-17(10)14-8-12(21-3)4-5-16(14)20-18/h4-9,20H,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| PCBioAssay
| n/a | n/a | 2.47E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
PCMD
Curated by PubChem BioAssay
| Assay Description Project Title: A screen for modulators of human Rad51, a key DNA repair protein Application Number: MH084119 Assay Submitter: Dr. Alex Mazin Submitte... |
PubChem Bioassay (2008)
BindingDB Entry DOI: 10.7270/Q2QN6558 |
More data for this Ligand-Target Pair | |
DNA repair protein RAD51 homolog 1
(Homo sapiens (Human)) | BDBM50174412
(9-Methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole ...)Show InChI InChI=1S/C18H16N2O/c1-10-15-9-19-7-6-13(15)11(2)18-17(10)14-8-12(21-3)4-5-16(14)20-18/h4-9,20H,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| PCBioAssay
| n/a | n/a | 2.68E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
PCMD
Curated by PubChem BioAssay
| Assay Description Project Title: A screen for modulators of human Rad51, a key DNA repair protein Application Number: MH084119 Assay Submitter: Dr. Alex Mazin Submitte... |
PubChem Bioassay (2008)
BindingDB Entry DOI: 10.7270/Q2VD6WW6 |
More data for this Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM50174412
(9-Methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole ...)Show InChI InChI=1S/C18H16N2O/c1-10-15-9-19-7-6-13(15)11(2)18-17(10)14-8-12(21-3)4-5-16(14)20-18/h4-9,20H,1-3H3 | PDB MMDB
NCI pathway KEGG
UniProtKB/SwissProt
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| PCBioAssay
| n/a | n/a | 5.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Molecular Libraries Screening Center
Curated by PubChem BioAssay
| Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer... |
PubChem Bioassay (2008)
BindingDB Entry DOI: 10.7270/Q23X8539 |
More data for this Ligand-Target Pair | |
Glucocorticoid receptor
(Homo sapiens (Human)) | BDBM50174412
(9-Methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole ...)Show InChI InChI=1S/C18H16N2O/c1-10-15-9-19-7-6-13(15)11(2)18-17(10)14-8-12(21-3)4-5-16(14)20-18/h4-9,20H,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
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| Article PubMed
| n/a | n/a | 9.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description Inhibition of glucocorticoid receptor-glucocorticoid complex transfected in rat R1 cells assessed as down-regulation of TPA-responsive element proinf... |
J Nat Prod 71: 1063-5 (2008)
Article DOI: 10.1021/np070655e BindingDB Entry DOI: 10.7270/Q23J3DVC |
More data for this Ligand-Target Pair | |
Reverse transcriptase
(Human immunodeficiency virus 1) | BDBM50174412
(9-Methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole ...)Show InChI InChI=1S/C18H16N2O/c1-10-15-9-19-7-6-13(15)11(2)18-17(10)14-8-12(21-3)4-5-16(14)20-18/h4-9,20H,1-3H3 | PDB MMDB
UniProtKB/TrEMBL
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| Article PubMed
| n/a | n/a | <5.42E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois
Curated by ChEMBL
| Assay Description Inhibition of HIV1 RT |
J Nat Prod 54: 143-54
Article DOI: 10.1021/np50073a012 BindingDB Entry DOI: 10.7270/Q2NK3HTG |
More data for this Ligand-Target Pair | |
Orotidine 5'-phosphate decarboxylase
(Aspergillus niger) | BDBM50174412
(9-Methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole ...)Show InChI InChI=1S/C18H16N2O/c1-10-15-9-19-7-6-13(15)11(2)18-17(10)14-8-12(21-3)4-5-16(14)20-18/h4-9,20H,1-3H3 | UniProtKB/SwissProt
GoogleScholar AffyNet
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| PCBioAssay
| n/a | n/a | n/a | n/a | >5.97E+4 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
| Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRISMC) Center Affiliation: The Scripps Research Institute, TS... |
PubChem Bioassay (2011)
BindingDB Entry DOI: 10.7270/Q2PK0DN5 |
More data for this Ligand-Target Pair | |
Melanocortin receptor 4
(Homo sapiens (Human)) | BDBM50174412
(9-Methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole ...)Show InChI InChI=1S/C18H16N2O/c1-10-15-9-19-7-6-13(15)11(2)18-17(10)14-8-12(21-3)4-5-16(14)20-18/h4-9,20H,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
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| PCBioAssay
| n/a | n/a | n/a | n/a | >8.93E+4 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
| Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRISMC) Center Affiliation: The Scripps Research Institute, TS... |
PubChem Bioassay (2012)
BindingDB Entry DOI: 10.7270/Q2QC0233 |
More data for this Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50174412
(9-Methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole ...)Show InChI InChI=1S/C18H16N2O/c1-10-15-9-19-7-6-13(15)11(2)18-17(10)14-8-12(21-3)4-5-16(14)20-18/h4-9,20H,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| PCBioAssay
| n/a | n/a | n/a | n/a | >6.47E+4 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
| Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRISMC) Center Affiliation: The Scripps Research Institute, TS... |
PubChem Bioassay (2012)
BindingDB Entry DOI: 10.7270/Q2KK99CT |
More data for this Ligand-Target Pair | |
Heat shock factor protein 1
(Mus musculus) | BDBM50174412
(9-Methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole ...)Show InChI InChI=1S/C18H16N2O/c1-10-15-9-19-7-6-13(15)11(2)18-17(10)14-8-12(21-3)4-5-16(14)20-18/h4-9,20H,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
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| PCBioAssay
| n/a | n/a | n/a | n/a | >2.60E+5 | n/a | n/a | n/a | n/a |
Broad Institute
Curated by PubChem BioAssay
| Assay Description Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie... |
PubChem Bioassay (2010)
BindingDB Entry DOI: 10.7270/Q2P55KXK |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase kinase 2
(Homo sapiens (Human)) | BDBM50174412
(9-Methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole ...)Show InChI InChI=1S/C18H16N2O/c1-10-15-9-19-7-6-13(15)11(2)18-17(10)14-8-12(21-3)4-5-16(14)20-18/h4-9,20H,1-3H3 | MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
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| PCBioAssay
| n/a | n/a | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a |
NMMLSC
Curated by PubChem BioAssay
| Assay Description University of New Mexico Assay Overview: Assay Support: 1R03MH084830-01 Project Title: TR-FRET HTS Assay for Inhibitors of MEKK2-MEK5 PB1 Domain... |
PubChem Bioassay (2009)
BindingDB Entry DOI: 10.7270/Q21Z42TP |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase kinase 2
(Homo sapiens (Human)) | BDBM50174412
(9-Methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole ...)Show InChI InChI=1S/C18H16N2O/c1-10-15-9-19-7-6-13(15)11(2)18-17(10)14-8-12(21-3)4-5-16(14)20-18/h4-9,20H,1-3H3 | MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
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| PCBioAssay
| n/a | n/a | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a |
NMMLSC
Curated by PubChem BioAssay
| Assay Description University of New Mexico Assay Overview: Assay Support: 1R03MH084830-01 Project Title: TR-FRET HTS Assay for Inhibitors of MEKK2-MEK5 PB1 Domain... |
PubChem Bioassay (2009)
BindingDB Entry DOI: 10.7270/Q25Q4THK |
More data for this Ligand-Target Pair | |
Streptokinase A
(Streptococcus pyogenes M1 GAS) | BDBM50174412
(9-Methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole ...)Show InChI InChI=1S/C18H16N2O/c1-10-15-9-19-7-6-13(15)11(2)18-17(10)14-8-12(21-3)4-5-16(14)20-18/h4-9,20H,1-3H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
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| PCBioAssay
| n/a | n/a | n/a | n/a | 1.50E+5 | n/a | n/a | n/a | n/a |
Broad Institute
Curated by PubChem BioAssay
| Assay Description Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa... |
PubChem Bioassay (2009)
BindingDB Entry DOI: 10.7270/Q2736PBV |
More data for this Ligand-Target Pair | |
Probable global transcription activator SNF2L2
(Homo sapiens (Human)) | BDBM50174412
(9-Methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole ...)Show InChI InChI=1S/C18H16N2O/c1-10-15-9-19-7-6-13(15)11(2)18-17(10)14-8-12(21-3)4-5-16(14)20-18/h4-9,20H,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| PCBioAssay
| n/a | n/a | n/a | n/a | 3.38E+3 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
| |
PubChem Bioassay (2013)
BindingDB Entry DOI: 10.7270/Q2GF0S4R |
More data for this Ligand-Target Pair | |