Found 4 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Lysophosphatidic acid receptor 5
(Homo sapiens (Human)) | BDBM251718
(US10100018, Example 54 | US9464060, 54)Show SMILES OC(=O)c1ccc(CN(CC2CC2)C(=O)c2ccc(Oc3ccccc3F)cc2F)cc1 Show InChI InChI=1S/C25H21F2NO4/c26-21-3-1-2-4-23(21)32-19-11-12-20(22(27)13-19)24(29)28(14-16-5-6-16)15-17-7-9-18(10-8-17)25(30)31/h1-4,7-13,16H,5-6,14-15H2,(H,30,31) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | 37 |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description Engagement of the LPA5 receptor by its ligand, oleoyl-L-α-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium into ... |
US Patent US9464060 (2016)
BindingDB Entry DOI: 10.7270/Q23R0RT0 |
More data for this Ligand-Target Pair | |
Lysophosphatidic acid receptor 1
(Homo sapiens (Human)) | BDBM251718
(US10100018, Example 54 | US9464060, 54)Show SMILES OC(=O)c1ccc(CN(CC2CC2)C(=O)c2ccc(Oc3ccccc3F)cc2F)cc1 Show InChI InChI=1S/C25H21F2NO4/c26-21-3-1-2-4-23(21)32-19-11-12-20(22(27)13-19)24(29)28(14-16-5-6-16)15-17-7-9-18(10-8-17)25(30)31/h1-4,7-13,16H,5-6,14-15H2,(H,30,31) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | 25 |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description Engagement of the LPA1 receptor by its ligand, oleoyl-L-α-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium i... |
US Patent US10100018 (2018)
BindingDB Entry DOI: 10.7270/Q2PR7Z0N |
More data for this Ligand-Target Pair | |
Lysophosphatidic acid receptor 1
(Homo sapiens (Human)) | BDBM251718
(US10100018, Example 54 | US9464060, 54)Show SMILES OC(=O)c1ccc(CN(CC2CC2)C(=O)c2ccc(Oc3ccccc3F)cc2F)cc1 Show InChI InChI=1S/C25H21F2NO4/c26-21-3-1-2-4-23(21)32-19-11-12-20(22(27)13-19)24(29)28(14-16-5-6-16)15-17-7-9-18(10-8-17)25(30)31/h1-4,7-13,16H,5-6,14-15H2,(H,30,31) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | 25 |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description Engagement of the LPA1 receptor by its ligand, oleoyl-L-α-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium i... |
US Patent US10100018 (2018)
BindingDB Entry DOI: 10.7270/Q2PR7Z0N |
More data for this Ligand-Target Pair | |
Lysophosphatidic acid receptor 1
(Homo sapiens (Human)) | BDBM251718
(US10100018, Example 54 | US9464060, 54)Show SMILES OC(=O)c1ccc(CN(CC2CC2)C(=O)c2ccc(Oc3ccccc3F)cc2F)cc1 Show InChI InChI=1S/C25H21F2NO4/c26-21-3-1-2-4-23(21)32-19-11-12-20(22(27)13-19)24(29)28(14-16-5-6-16)15-17-7-9-18(10-8-17)25(30)31/h1-4,7-13,16H,5-6,14-15H2,(H,30,31) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | 37 |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description Engagement of the LPA1 receptor by its ligand, oleoyl-L-α-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium into ... |
US Patent US9464060 (2016)
BindingDB Entry DOI: 10.7270/Q23R0RT0 |
More data for this Ligand-Target Pair | |