Found 33 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Carbonic anhydrase
(Dicentrarchus labrax) | BDBM26189
(α-CA inhibitor, 13 | 1,3-Dihydroxybenzene, XI...)Show InChI InChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H | UniProtKB/TrEMBL
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| Article PubMed
| 6.42E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Gumushane University
Curated by ChEMBL
| Assay Description Inhibition of Dicentrarchus labrax CA using 4-nitrophenylacetate substrate by esterase assay |
Bioorg Med Chem Lett 21: 4259-62 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.071 BindingDB Entry DOI: 10.7270/Q2PC32Q0 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 5B, mitochondrial
(Homo sapiens (Human)) | BDBM26189
(α-CA inhibitor, 13 | 1,3-Dihydroxybenzene, XI...)Show InChI InChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H | Reactome pathway KEGG
UniProtKB/SwissProt
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| Article PubMed
| 7.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
| Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic... |
Bioorg Med Chem 16: 7424-8 (2008)
Article DOI: 10.1016/j.bmc.2008.06.013 BindingDB Entry DOI: 10.7270/Q2X065C8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM26189
(α-CA inhibitor, 13 | 1,3-Dihydroxybenzene, XI...)Show InChI InChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H | PDB MMDB
Reactome pathway KEGG
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| Article PubMed
| 7.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
| Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic... |
Bioorg Med Chem 16: 7424-8 (2008)
Article DOI: 10.1016/j.bmc.2008.06.013 BindingDB Entry DOI: 10.7270/Q2X065C8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM26189
(α-CA inhibitor, 13 | 1,3-Dihydroxybenzene, XI...)Show InChI InChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H | PDB MMDB
Reactome pathway KEGG
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| Article PubMed
| 7.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 2 by stopped-flow CO2 hydrase assay |
Bioorg Med Chem Lett 18: 3593-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.077 BindingDB Entry DOI: 10.7270/Q2XP75TC |
More data for this Ligand-Target Pair | 3D Structure (docked) |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM26189
(α-CA inhibitor, 13 | 1,3-Dihydroxybenzene, XI...)Show InChI InChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H | PDB MMDB
Reactome pathway KEGG
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| Article PubMed
| 7.70E+3 | -29.2 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Universita degli Studi di Firenze
| Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic... |
Bioorg Med Chem 16: 7424-8 (2008)
Article DOI: 10.1016/j.bmc.2008.06.013 BindingDB Entry DOI: 10.7270/Q2X065C8 |
More data for this Ligand-Target Pair | 3D Structure (docked) |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM26189
(α-CA inhibitor, 13 | 1,3-Dihydroxybenzene, XI...)Show InChI InChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H | PDB MMDB
Reactome pathway KEGG
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| Article PubMed
| 7.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AgriIbrahim£e£en University
Curated by ChEMBL
| Assay Description Inhibition of human erythrocytes CA2 using 4-nitrophenylacetate as substrate by esterase assay |
Bioorg Med Chem Lett 25: 3261-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.073 BindingDB Entry DOI: 10.7270/Q2W37Z39 |
More data for this Ligand-Target Pair | 3D Structure (docked) |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM26189
(α-CA inhibitor, 13 | 1,3-Dihydroxybenzene, XI...)Show InChI InChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H | Reactome pathway KEGG
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| Article PubMed
| 8.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
| Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic... |
Bioorg Med Chem 16: 7424-8 (2008)
Article DOI: 10.1016/j.bmc.2008.06.013 BindingDB Entry DOI: 10.7270/Q2X065C8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM26189
(α-CA inhibitor, 13 | 1,3-Dihydroxybenzene, XI...)Show InChI InChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H | PDB MMDB
Reactome pathway KEGG
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| Article PubMed
| 9.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Ondokuz Mayis University
| Assay Description Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ... |
J Enzyme Inhib Med Chem 28: 283-8 (2013)
Article DOI: 10.3109/14756366.2011.643303 BindingDB Entry DOI: 10.7270/Q2QR4W1F |
More data for this Ligand-Target Pair | 3D Structure (docked) |
Carbonic anhydrase 14
(Homo sapiens (Human)) | BDBM26189
(α-CA inhibitor, 13 | 1,3-Dihydroxybenzene, XI...)Show InChI InChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H | PDB
Reactome pathway KEGG
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| 1.07E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
| Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic... |
Bioorg Med Chem 16: 7424-8 (2008)
Article DOI: 10.1016/j.bmc.2008.06.013 BindingDB Entry DOI: 10.7270/Q2X065C8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 13
(Mus musculus (mouse)) | BDBM26189
(α-CA inhibitor, 13 | 1,3-Dihydroxybenzene, XI...)Show InChI InChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H | PDB MMDB
Reactome pathway KEGG
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| 6.26E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
| Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic... |
Bioorg Med Chem 16: 7424-8 (2008)
Article DOI: 10.1016/j.bmc.2008.06.013 BindingDB Entry DOI: 10.7270/Q2X065C8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM26189
(α-CA inhibitor, 13 | 1,3-Dihydroxybenzene, XI...)Show InChI InChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H | PDB MMDB
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| Article PubMed
| 6.97E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
| Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic... |
Bioorg Med Chem 16: 7424-8 (2008)
Article DOI: 10.1016/j.bmc.2008.06.013 BindingDB Entry DOI: 10.7270/Q2X065C8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 3
(Bos taurus (Cattle)) | BDBM26189
(α-CA inhibitor, 13 | 1,3-Dihydroxybenzene, XI...)Show InChI InChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H | PDB
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| 1.96E+5 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Ege University
| Assay Description CA activity was assayed by following the change in absorbance at 348 nm of 4-NPA to 4-nitrophenylate ion over a period of 3 min at 25°C using a spect... |
J Enzyme Inhib Med Chem 28: 412-7 (2013)
Article DOI: 10.3109/14756366.2011.651464 BindingDB Entry DOI: 10.7270/Q2W66JQ2 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 3
(Bos taurus (Cattle)) | BDBM26189
(α-CA inhibitor, 13 | 1,3-Dihydroxybenzene, XI...)Show InChI InChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H | PDB
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| 2.19E+5 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Ondokuz Mayis University
| Assay Description Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ... |
J Enzyme Inhib Med Chem 28: 283-8 (2013)
Article DOI: 10.3109/14756366.2011.643303 BindingDB Entry DOI: 10.7270/Q2QR4W1F |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 15
(Mus musculus) | BDBM26189
(α-CA inhibitor, 13 | 1,3-Dihydroxybenzene, XI...)Show InChI InChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H | KEGG
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| Article PubMed
| 3.85E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant carbonic anhydrase 15 by stopped-flow CO2 hydrase assay |
Bioorg Med Chem Lett 18: 3593-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.077 BindingDB Entry DOI: 10.7270/Q2XP75TC |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 6
(Homo sapiens (Human)) | BDBM26189
(α-CA inhibitor, 13 | 1,3-Dihydroxybenzene, XI...)Show InChI InChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H | PDB
UniProtKB/SwissProt
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| Article PubMed
| 5.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
| Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic... |
Bioorg Med Chem 16: 7424-8 (2008)
Article DOI: 10.1016/j.bmc.2008.06.013 BindingDB Entry DOI: 10.7270/Q2X065C8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 4
(Homo sapiens (Human)) | BDBM26189
(α-CA inhibitor, 13 | 1,3-Dihydroxybenzene, XI...)Show InChI InChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H | PDB MMDB
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| Article PubMed
| 5.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
| Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic... |
Bioorg Med Chem 16: 7424-8 (2008)
Article DOI: 10.1016/j.bmc.2008.06.013 BindingDB Entry DOI: 10.7270/Q2X065C8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 3
(Homo sapiens (Human)) | BDBM26189
(α-CA inhibitor, 13 | 1,3-Dihydroxybenzene, XI...)Show InChI InChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H | PDB MMDB
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| Article PubMed
| 6.05E+5 | -18.4 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Universita degli Studi di Firenze
| Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic... |
Bioorg Med Chem 16: 7424-8 (2008)
Article DOI: 10.1016/j.bmc.2008.06.013 BindingDB Entry DOI: 10.7270/Q2X065C8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 4
(Homo sapiens (Human)) | BDBM26189
(α-CA inhibitor, 13 | 1,3-Dihydroxybenzene, XI...)Show InChI InChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H | PDB MMDB
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| Article PubMed
| 6.34E+5 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Ondokuz Mayis University
| Assay Description Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ... |
J Enzyme Inhib Med Chem 28: 283-8 (2013)
Article DOI: 10.3109/14756366.2011.643303 BindingDB Entry DOI: 10.7270/Q2QR4W1F |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 7
(Homo sapiens (Human)) | BDBM26189
(α-CA inhibitor, 13 | 1,3-Dihydroxybenzene, XI...)Show InChI InChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H | PDB MMDB
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| Article PubMed
| 6.44E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Firenze
| Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic... |
Bioorg Med Chem 16: 7424-8 (2008)
Article DOI: 10.1016/j.bmc.2008.06.013 BindingDB Entry DOI: 10.7270/Q2X065C8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM26189
(α-CA inhibitor, 13 | 1,3-Dihydroxybenzene, XI...)Show InChI InChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H | PDB MMDB
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| Article PubMed
| 7.95E+5 | -17.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Universita degli Studi di Firenze
| Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic... |
Bioorg Med Chem 16: 7424-8 (2008)
Article DOI: 10.1016/j.bmc.2008.06.013 BindingDB Entry DOI: 10.7270/Q2X065C8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM26189
(α-CA inhibitor, 13 | 1,3-Dihydroxybenzene, XI...)Show InChI InChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H | PDB MMDB
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| Article PubMed
| 7.95E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human carbonic anhydrase 1 by stopped-flow CO2 hydrase assay |
Bioorg Med Chem Lett 18: 3593-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.04.077 BindingDB Entry DOI: 10.7270/Q2XP75TC |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM26189
(α-CA inhibitor, 13 | 1,3-Dihydroxybenzene, XI...)Show InChI InChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H | PDB MMDB
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| Article PubMed
| 7.95E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AgriIbrahim£e£en University
Curated by ChEMBL
| Assay Description Inhibition of human erythrocytes CA1 using 4-nitrophenylacetate as substrate by esterase assay |
Bioorg Med Chem Lett 25: 3261-3 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.073 BindingDB Entry DOI: 10.7270/Q2W37Z39 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM26189
(α-CA inhibitor, 13 | 1,3-Dihydroxybenzene, XI...)Show InChI InChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H | PDB MMDB
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| Article PubMed
| 8.28E+5 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Ondokuz Mayis University
| Assay Description Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ... |
J Enzyme Inhib Med Chem 28: 283-8 (2013)
Article DOI: 10.3109/14756366.2011.643303 BindingDB Entry DOI: 10.7270/Q2QR4W1F |
More data for this Ligand-Target Pair | |
Prolyl 4-hydroxylase subunit alpha-1
(Gallus gallus (Chicken)) | BDBM26189
(α-CA inhibitor, 13 | 1,3-Dihydroxybenzene, XI...)Show InChI InChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H | PDB
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| PubMed
| 1.02E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oulu
| Assay Description Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase. |
J Biol Chem 261: 7819-23 (1986)
BindingDB Entry DOI: 10.7270/Q2SJ1J6Z |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM26189
(α-CA inhibitor, 13 | 1,3-Dihydroxybenzene, XI...)Show InChI InChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H | PDB
KEGG
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| Article PubMed
| n/a | n/a | 3.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania School of Medicine
Curated by ChEMBL
| Assay Description Inhibition of peroxidase activity of COX1 in heep seminal vesicle by TMPD assay |
J Nat Prod 67: 1777-82 (2004)
Article DOI: 10.1021/np0498410 BindingDB Entry DOI: 10.7270/Q2XD12JH |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM26189
(α-CA inhibitor, 13 | 1,3-Dihydroxybenzene, XI...)Show InChI InChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H | PDB
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Patents
Similars
| Article PubMed
| n/a | n/a | 3.08E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania School of Medicine
Curated by ChEMBL
| Assay Description Inhibition of cyclooxygenase activity of COX1 in sheep seminal vesicle in presence of 1 mM phenol by cyclooxygenase assay |
J Nat Prod 67: 1777-82 (2004)
Article DOI: 10.1021/np0498410 BindingDB Entry DOI: 10.7270/Q2XD12JH |
More data for this Ligand-Target Pair | |
Estrogen receptor
(Homo sapiens (Human)) | BDBM26189
(α-CA inhibitor, 13 | 1,3-Dihydroxybenzene, XI...)Show InChI InChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H | PDB
UniProtKB/SwissProt
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Patents
Similars
| US Patent
| n/a | n/a | >2.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
SABIC GLOBAL TECHNOLOGIES B.V.
US Patent
| Assay Description Competitive binding assays were performed by incubating rhER alpha (α) and beta 1 (β1) receptors with 10 nM [3H]estradiol (the radio ligand... |
US Patent US9688816 (2017)
BindingDB Entry DOI: 10.7270/Q2WD3XR0 |
More data for this Ligand-Target Pair | |
Estrogen receptor beta
(Homo sapiens (Human)) | BDBM26189
(α-CA inhibitor, 13 | 1,3-Dihydroxybenzene, XI...)Show InChI InChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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Patents
Similars
| US Patent
| n/a | n/a | >2.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
SABIC GLOBAL TECHNOLOGIES B.V.
US Patent
| Assay Description Competitive binding assays were performed by incubating rhER alpha (α) and beta 1 (β1) receptors with 10 nM [3H]estradiol (the radio ligand... |
US Patent US9688816 (2017)
BindingDB Entry DOI: 10.7270/Q2WD3XR0 |
More data for this Ligand-Target Pair | |
Polyphenol oxidase 2
(Agaricus bisporus (Common mushroom)) | BDBM26189
(α-CA inhibitor, 13 | 1,3-Dihydroxybenzene, XI...)Show InChI InChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H | UniProtKB/SwissProt
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Patents
Similars
| Article PubMed
| n/a | n/a | 6.52E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Murcia
Curated by ChEMBL
| Assay Description Inhibition of mushroom tyrosinase using L-dopa as substrate assessed as diphenolase activity by spectrophotometric analysis |
Bioorg Med Chem 24: 4434-4443 (2016)
Article DOI: 10.1016/j.bmc.2016.07.048 BindingDB Entry DOI: 10.7270/Q24F1SP6 |
More data for this Ligand-Target Pair | |
Polyphenol oxidase 2
(Agaricus bisporus (Common mushroom)) | BDBM26189
(α-CA inhibitor, 13 | 1,3-Dihydroxybenzene, XI...)Show InChI InChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H | UniProtKB/SwissProt
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Patents
Similars
| Article PubMed
| n/a | n/a | 1.13E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Murcia
Curated by ChEMBL
| Assay Description Inhibition of mushroom tyrosinase using L-tyrosine as substrate assessed as monophenolase activity by spectrophotometric analysis |
Bioorg Med Chem 24: 4434-4443 (2016)
Article DOI: 10.1016/j.bmc.2016.07.048 BindingDB Entry DOI: 10.7270/Q24F1SP6 |
More data for this Ligand-Target Pair | |
Polyphenol oxidase 2
(Agaricus bisporus (Common mushroom)) | BDBM26189
(α-CA inhibitor, 13 | 1,3-Dihydroxybenzene, XI...)Show InChI InChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H | UniProtKB/SwissProt
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Patents
Similars
| Article PubMed
| n/a | n/a | 1.44E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Università degli Studi di Cagliari
Curated by ChEMBL
| Assay Description Inhibition of mushroom tyrosine kinase assessed as oxidation of 0.25 mM L-3,4-dihydroxyphenylalanine |
Bioorg Med Chem Lett 19: 36-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.11.020 BindingDB Entry DOI: 10.7270/Q2445MB2 |
More data for this Ligand-Target Pair | |
Tyrosinase
(Homo sapiens (Human)) | BDBM26189
(α-CA inhibitor, 13 | 1,3-Dihydroxybenzene, XI...)Show InChI InChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H | KEGG
UniProtKB/SwissProt
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Patents
Similars
| Article PubMed
| n/a | n/a | >3.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human His-tagged tyrosinase expressed in HEK 293 cells using L-DOPA as substrate by MBTH based assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c00994 BindingDB Entry DOI: 10.7270/Q2PV6Q29 |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Ovis aries (Sheep)) | BDBM26189
(α-CA inhibitor, 13 | 1,3-Dihydroxybenzene, XI...)Show InChI InChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H | PDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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Patents
Similars
| Article PubMed
| n/a | n/a | n/a | 8.69E+4 | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania School of Medicine
Curated by ChEMBL
| Assay Description Binding affinity to COX1 in sheep seminal vesicle |
J Nat Prod 67: 1777-82 (2004)
Article DOI: 10.1021/np0498410 BindingDB Entry DOI: 10.7270/Q2XD12JH |
More data for this Ligand-Target Pair | |