Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
CAAX prenyl protease 2 (Homo sapiens (Human)) | BDBM50500099 (CHEMBL3741765) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
New York University Abu Dhabi Curated by ChEMBL | Assay Description Inhibition of human Rce1-mediated CaaX protease activity using ABZ-KSKTKC(farnesyl)QIIM and ABZ-KSKTKC(farnesyl)VIQI as substrate assessed as residua... | Bioorg Med Chem 24: 160-78 (2016) Article DOI: 10.1016/j.bmc.2015.11.043 BindingDB Entry DOI: 10.7270/Q2NS0XXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CAAX prenyl protease 2 (Homo sapiens (Human)) | BDBM50500092 (CHEMBL3741937) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
New York University Abu Dhabi Curated by ChEMBL | Assay Description Inhibition of human Rce1-mediated CaaX protease activity using ABZ-KSKTKC(farnesyl)QIIM and ABZ-KSKTKC(farnesyl)VIQI as substrate assessed as residua... | Bioorg Med Chem 24: 160-78 (2016) Article DOI: 10.1016/j.bmc.2015.11.043 BindingDB Entry DOI: 10.7270/Q2NS0XXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CAAX prenyl protease 2 (Homo sapiens (Human)) | BDBM50500097 (CHEMBL3740962) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
New York University Abu Dhabi Curated by ChEMBL | Assay Description Inhibition of human Rce1-mediated CaaX protease activity using ABZ-KSKTKC(farnesyl)QIIM and ABZ-KSKTKC(farnesyl)VIQI as substrate assessed as residua... | Bioorg Med Chem 24: 160-78 (2016) Article DOI: 10.1016/j.bmc.2015.11.043 BindingDB Entry DOI: 10.7270/Q2NS0XXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CAAX prenyl protease 2 (Homo sapiens (Human)) | BDBM50500105 (CHEMBL3740249) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
New York University Abu Dhabi Curated by ChEMBL | Assay Description Inhibition of human Rce1-mediated CaaX protease activity using ABZ-KSKTKC(farnesyl)QIIM and ABZ-KSKTKC(farnesyl)VIQI as substrate assessed as residua... | Bioorg Med Chem 24: 160-78 (2016) Article DOI: 10.1016/j.bmc.2015.11.043 BindingDB Entry DOI: 10.7270/Q2NS0XXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CAAX prenyl protease 2 (Homo sapiens (Human)) | BDBM50500103 (CHEMBL3742211) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
New York University Abu Dhabi Curated by ChEMBL | Assay Description Inhibition of human Rce1-mediated CaaX protease activity using ABZ-KSKTKC(farnesyl)QIIM and ABZ-KSKTKC(farnesyl)VIQI as substrate assessed as residua... | Bioorg Med Chem 24: 160-78 (2016) Article DOI: 10.1016/j.bmc.2015.11.043 BindingDB Entry DOI: 10.7270/Q2NS0XXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CAAX prenyl protease 2 (Homo sapiens (Human)) | BDBM50500098 (CHEMBL3741101) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
New York University Abu Dhabi Curated by ChEMBL | Assay Description Inhibition of human Rce1-mediated CaaX protease activity using ABZ-KSKTKC(farnesyl)QIIM and ABZ-KSKTKC(farnesyl)VIQI as substrate assessed as residua... | Bioorg Med Chem 24: 160-78 (2016) Article DOI: 10.1016/j.bmc.2015.11.043 BindingDB Entry DOI: 10.7270/Q2NS0XXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CAAX prenyl protease 2 (Homo sapiens (Human)) | BDBM50500106 (CHEMBL3741673) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
New York University Abu Dhabi Curated by ChEMBL | Assay Description Inhibition of human Rce1-mediated CaaX protease activity using ABZ-KSKTKC(farnesyl)QIIM and ABZ-KSKTKC(farnesyl)VIQI as substrate assessed as residua... | Bioorg Med Chem 24: 160-78 (2016) Article DOI: 10.1016/j.bmc.2015.11.043 BindingDB Entry DOI: 10.7270/Q2NS0XXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CAAX prenyl protease 2 (Homo sapiens (Human)) | BDBM50500094 (CHEMBL3740203) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
New York University Abu Dhabi Curated by ChEMBL | Assay Description Inhibition of human Rce1-mediated CaaX protease activity using ABZ-KSKTKC(farnesyl)QIIM and ABZ-KSKTKC(farnesyl)VIQI as substrate assessed as residua... | Bioorg Med Chem 24: 160-78 (2016) Article DOI: 10.1016/j.bmc.2015.11.043 BindingDB Entry DOI: 10.7270/Q2NS0XXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CAAX prenyl protease 2 (Homo sapiens (Human)) | BDBM50500101 (CHEMBL1979298) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
New York University Abu Dhabi Curated by ChEMBL | Assay Description Inhibition of human Rce1-mediated CaaX protease activity using ABZ-KSKTKC(farnesyl)QIIM and ABZ-KSKTKC(farnesyl)VIQI as substrate assessed as residua... | Bioorg Med Chem 24: 160-78 (2016) Article DOI: 10.1016/j.bmc.2015.11.043 BindingDB Entry DOI: 10.7270/Q2NS0XXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CAAX prenyl protease 2 (Homo sapiens (Human)) | BDBM50096860 ((E)-3-Biphenyl-4-yl-N-{2-[3-(2,3-dimethyl-phenylsu...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Philipps-Universität Marburg Curated by ChEMBL | Assay Description Inhibition of recombinant prenyl protein-specific protease Rce1 expressed in Sf9 cells at 10 uM | Bioorg Med Chem Lett 11: 425-7 (2001) BindingDB Entry DOI: 10.7270/Q20G3JF1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CAAX prenyl protease 2 (Homo sapiens (Human)) | BDBM50096861 (CHEMBL440905 | Heptadecanoic acid {[3-(2,3-dimethy...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Philipps-Universität Marburg Curated by ChEMBL | Assay Description Inhibition of recombinant prenyl protein-specific protease Rce1 expressed in Sf9 cells at 10 uM | Bioorg Med Chem Lett 11: 425-7 (2001) BindingDB Entry DOI: 10.7270/Q20G3JF1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CAAX prenyl protease 2 (Homo sapiens (Human)) | BDBM50500091 (CHEMBL3740563) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
New York University Abu Dhabi Curated by ChEMBL | Assay Description Inhibition of human Rce1-mediated CaaX protease activity using ABZ-KSKTKC(farnesyl)QIIM and ABZ-KSKTKC(farnesyl)VIQI as substrate assessed as residua... | Bioorg Med Chem 24: 160-78 (2016) Article DOI: 10.1016/j.bmc.2015.11.043 BindingDB Entry DOI: 10.7270/Q2NS0XXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CAAX prenyl protease 2 (Homo sapiens (Human)) | BDBM50480670 (CHEMBL553161) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of British Columbia Curated by ChEMBL | Assay Description Inhibition of human RCE1 | J Nat Prod 72: 1106-9 (2009) Article DOI: 10.1021/np900042r BindingDB Entry DOI: 10.7270/Q2930X0M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CAAX prenyl protease 2 (Homo sapiens (Human)) | BDBM50500100 (CHEMBL3740034) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
New York University Abu Dhabi Curated by ChEMBL | Assay Description Inhibition of human Rce1-mediated CaaX protease activity using ABZ-KSKTKC(farnesyl)QIIM and ABZ-KSKTKC(farnesyl)VIQI as substrate assessed as residua... | Bioorg Med Chem 24: 160-78 (2016) Article DOI: 10.1016/j.bmc.2015.11.043 BindingDB Entry DOI: 10.7270/Q2NS0XXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CAAX prenyl protease 2 (Homo sapiens (Human)) | BDBM50500095 (CHEMBL2003928) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
New York University Abu Dhabi Curated by ChEMBL | Assay Description Inhibition of human Rce1-mediated CaaX protease activity using ABZ-KSKTKC(farnesyl)QIIM and ABZ-KSKTKC(farnesyl)VIQI as substrate assessed as residua... | Bioorg Med Chem 24: 160-78 (2016) Article DOI: 10.1016/j.bmc.2015.11.043 BindingDB Entry DOI: 10.7270/Q2NS0XXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CAAX prenyl protease 2 (Homo sapiens (Human)) | BDBM50500107 (CHEMBL3741464) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
New York University Abu Dhabi Curated by ChEMBL | Assay Description Inhibition of human Rce1-mediated CaaX protease activity using ABZ-KSKTKC(farnesyl)QIIM and ABZ-KSKTKC(farnesyl)VIQI as substrate assessed as residua... | Bioorg Med Chem 24: 160-78 (2016) Article DOI: 10.1016/j.bmc.2015.11.043 BindingDB Entry DOI: 10.7270/Q2NS0XXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CAAX prenyl protease 2 (Homo sapiens (Human)) | BDBM50500102 (CHEMBL3740606) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
New York University Abu Dhabi Curated by ChEMBL | Assay Description Inhibition of human Rce1-mediated CaaX protease activity using ABZ-KSKTKC(farnesyl)QIIM and ABZ-KSKTKC(farnesyl)VIQI as substrate assessed as residua... | Bioorg Med Chem 24: 160-78 (2016) Article DOI: 10.1016/j.bmc.2015.11.043 BindingDB Entry DOI: 10.7270/Q2NS0XXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CAAX prenyl protease 2 (Homo sapiens (Human)) | BDBM50500109 (CHEMBL3740547) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
New York University Abu Dhabi Curated by ChEMBL | Assay Description Inhibition of human Rce1-mediated CaaX protease activity using ABZ-KSKTKC(farnesyl)QIIM and ABZ-KSKTKC(farnesyl)VIQI as substrate assessed as residua... | Bioorg Med Chem 24: 160-78 (2016) Article DOI: 10.1016/j.bmc.2015.11.043 BindingDB Entry DOI: 10.7270/Q2NS0XXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CAAX prenyl protease 2 (Homo sapiens (Human)) | BDBM50500093 (CHEMBL2006267) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
New York University Abu Dhabi Curated by ChEMBL | Assay Description Inhibition of human Rce1-mediated CaaX protease activity using ABZ-KSKTKC(farnesyl)QIIM and ABZ-KSKTKC(farnesyl)VIQI as substrate assessed as residua... | Bioorg Med Chem 24: 160-78 (2016) Article DOI: 10.1016/j.bmc.2015.11.043 BindingDB Entry DOI: 10.7270/Q2NS0XXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CAAX prenyl protease 2 (Homo sapiens (Human)) | BDBM50096862 ((9Z,12Z)-Octadeca-9,12-dienoic acid {2-[3-(2,3-dim...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Philipps-Universität Marburg Curated by ChEMBL | Assay Description Inhibition of recombinant prenyl protein-specific protease Rcel expressed in Sf9 cells | Bioorg Med Chem Lett 11: 425-7 (2001) BindingDB Entry DOI: 10.7270/Q20G3JF1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CAAX prenyl protease 2 (Homo sapiens (Human)) | BDBM50500096 (CHEMBL3739720) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
New York University Abu Dhabi Curated by ChEMBL | Assay Description Inhibition of human Rce1-mediated CaaX protease activity using ABZ-KSKTKC(farnesyl)QIIM and ABZ-KSKTKC(farnesyl)VIQI as substrate assessed as residua... | Bioorg Med Chem 24: 160-78 (2016) Article DOI: 10.1016/j.bmc.2015.11.043 BindingDB Entry DOI: 10.7270/Q2NS0XXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CAAX prenyl protease 2 (Homo sapiens (Human)) | BDBM50500108 (CHEMBL3740917) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
New York University Abu Dhabi Curated by ChEMBL | Assay Description Inhibition of human Rce1-mediated CaaX protease activity using ABZ-KSKTKC(farnesyl)QIIM and ABZ-KSKTKC(farnesyl)VIQI as substrate assessed as residua... | Bioorg Med Chem 24: 160-78 (2016) Article DOI: 10.1016/j.bmc.2015.11.043 BindingDB Entry DOI: 10.7270/Q2NS0XXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CAAX prenyl protease 2 (Homo sapiens (Human)) | BDBM50480671 (CHEMBL555914) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of British Columbia Curated by ChEMBL | Assay Description Inhibition of human RCE1 | J Nat Prod 72: 1106-9 (2009) Article DOI: 10.1021/np900042r BindingDB Entry DOI: 10.7270/Q2930X0M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CAAX prenyl protease 2 (Homo sapiens (Human)) | BDBM50500104 (CHEMBL3739592) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
New York University Abu Dhabi Curated by ChEMBL | Assay Description Inhibition of human Rce1-mediated CaaX protease activity using ABZ-KSKTKC(farnesyl)QIIM and ABZ-KSKTKC(farnesyl)VIQI as substrate assessed as residua... | Bioorg Med Chem 24: 160-78 (2016) Article DOI: 10.1016/j.bmc.2015.11.043 BindingDB Entry DOI: 10.7270/Q2NS0XXQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CAAX prenyl protease 2 (Homo sapiens (Human)) | BDBM50480672 (CHEMBL561185) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.35E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of British Columbia Curated by ChEMBL | Assay Description Inhibition of human RCE1 | J Nat Prod 72: 1106-9 (2009) Article DOI: 10.1021/np900042r BindingDB Entry DOI: 10.7270/Q2930X0M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
CAAX prenyl protease 2 (Homo sapiens (Human)) | BDBM50480669 (CHEMBL558514) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.98E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of British Columbia Curated by ChEMBL | Assay Description Inhibition of human RCE1 | J Nat Prod 72: 1106-9 (2009) Article DOI: 10.1021/np900042r BindingDB Entry DOI: 10.7270/Q2930X0M | |||||||||||
More data for this Ligand-Target Pair |