BindingDB PrimarySearch

Found 5 hits Enz. Inhib. hit(s) with Target = 'Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (Homo sapiens (Human))	BDBM50356009 (CHEMBL1911368) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Noncompetitive inhibition of GFAT in presence of fructose-6-phosphate				Bioorg Med Chem Lett 21: 6264-9 (2011) Article DOI: 10.1016/j.bmcl.2011.09.009 BindingDB Entry DOI: 10.7270/Q21J9B6P
Hoffmann-La Roche Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (Homo sapiens (Human))	BDBM50356009 (CHEMBL1911368) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Competitive inhibition of GFAT in presence of glutamine				Bioorg Med Chem Lett 21: 6264-9 (2011) Article DOI: 10.1016/j.bmcl.2011.09.009 BindingDB Entry DOI: 10.7270/Q21J9B6P
Hoffmann-La Roche Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (Homo sapiens (Human))	BDBM50356010 (CHEMBL1911372) Show SMILES N[C@@H](CNC(=O)CBr)C(O)=O \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Irreversible inhibition of GFAT				Bioorg Med Chem Lett 21: 6264-9 (2011) Article DOI: 10.1016/j.bmcl.2011.09.009 BindingDB Entry DOI: 10.7270/Q21J9B6P
Hoffmann-La Roche Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (Homo sapiens (Human))	BDBM50356011 (CHEMBL1911373) Show SMILES COC(=O)\C=C\C(=O)NC[C@H](N)C(O)=O \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Irreversible inhibition of GFAT				Bioorg Med Chem Lett 21: 6264-9 (2011) Article DOI: 10.1016/j.bmcl.2011.09.009 BindingDB Entry DOI: 10.7270/Q21J9B6P
Hoffmann-La Roche Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (Homo sapiens (Human))	BDBM50356012 (AAPTAMINE) Show SMILES COc1cc2ccnc3cc[nH]c(c1OC)c23 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. Curated by ChEMBL					Assay Description Inhibition of GFAT using N-acetylglucosamine 6-phosphate as substrate				Bioorg Med Chem Lett 21: 6264-9 (2011) Article DOI: 10.1016/j.bmcl.2011.09.009 BindingDB Entry DOI: 10.7270/Q21J9B6P
Hoffmann-La Roche Inc. Curated by ChEMBL					More data for this Ligand-Target Pair