Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
HIV WT-A pol protein (wild-type clade A) (Human immunodeficiency virus) | BDBM8125 ((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a |
Massachusetts Institute of Technology | Assay Description Drug susceptibility assays were carried out by Monogram Bioscience against wild-type HIV-1 control and patient-derived strains of wild-type HIV-1 fro... | ACS Chem Biol 8: 2433-41 (2013) Article DOI: 10.1021/cb400468c BindingDB Entry DOI: 10.7270/Q2R2101Z | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
HIV WT-A pol protein (wild-type clade A) (Human immunodeficiency virus) | BDBM104103 (N-[(1S,2R)-3-[(6-Benzothiazolylsulfonyl)(cyclohexy...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 48.6 | n/a | n/a | n/a | n/a |
Massachusetts Institute of Technology | Assay Description Drug susceptibility assays were carried out by Monogram Bioscience against wild-type HIV-1 control and patient-derived strains of wild-type HIV-1 fro... | ACS Chem Biol 8: 2433-41 (2013) Article DOI: 10.1021/cb400468c BindingDB Entry DOI: 10.7270/Q2R2101Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
HIV WT-A pol protein (wild-type clade A) (Human immunodeficiency virus) | BDBM104107 ((2S,3S)-2-(Acetylamino)-N-[(1S,2R)-2-hydroxy-3-[[(...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a |
Massachusetts Institute of Technology | Assay Description Drug susceptibility assays were carried out by Monogram Bioscience against wild-type HIV-1 control and patient-derived strains of wild-type HIV-1 fro... | ACS Chem Biol 8: 2433-41 (2013) Article DOI: 10.1021/cb400468c BindingDB Entry DOI: 10.7270/Q2R2101Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
HIV WT-A pol protein (wild-type clade A) (Human immunodeficiency virus) | BDBM577 ((3S)-oxolan-3-yl N-[(2S,3R)-4-[(4-aminobenzene)(2-...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a |
Massachusetts Institute of Technology | Assay Description Drug susceptibility assays were carried out by Monogram Bioscience against wild-type HIV-1 control and patient-derived strains of wild-type HIV-1 fro... | ACS Chem Biol 8: 2433-41 (2013) Article DOI: 10.1021/cb400468c BindingDB Entry DOI: 10.7270/Q2R2101Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
HIV WT-A pol protein (wild-type clade A) (Human immunodeficiency virus) | BDBM104102 ((2S,3S)-2-(Acetylamino)-N-[(1S,2R)-3-[(6-benzothia...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 2.30 | n/a | n/a | n/a | n/a |
Massachusetts Institute of Technology | Assay Description Drug susceptibility assays were carried out by Monogram Bioscience against wild-type HIV-1 control and patient-derived strains of wild-type HIV-1 fro... | ACS Chem Biol 8: 2433-41 (2013) Article DOI: 10.1021/cb400468c BindingDB Entry DOI: 10.7270/Q2R2101Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
HIV WT-A pol protein (wild-type clade A) (Human immunodeficiency virus) | BDBM104108 (N-[(1S,2R)-3-[(Cyclohexylmethyl)[(4-methoxyphenyl)...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 38.4 | n/a | n/a | n/a | n/a |
Massachusetts Institute of Technology | Assay Description Drug susceptibility assays were carried out by Monogram Bioscience against wild-type HIV-1 control and patient-derived strains of wild-type HIV-1 fro... | ACS Chem Biol 8: 2433-41 (2013) Article DOI: 10.1021/cb400468c BindingDB Entry DOI: 10.7270/Q2R2101Z | |||||||||||
More data for this Ligand-Target Pair |