Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 5.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh Chemical Diversity Center (UP-CDC) Curated by ChEMBL | Assay Description Inhibition of estrogen binding to GPR30 (unknown origin) | J Med Chem 56: 7161-76 (2013) Article DOI: 10.1021/jm400132d BindingDB Entry DOI: 10.7270/Q2V69M09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 5.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of New Mexico Health Sciences Center Curated by ChEMBL | Assay Description Displacement of E2-Alexa633 from GFP-tagged GPR30 expressed in COS7 cells by FACS | Nat Chem Biol 2: 207-12 (2006) Article DOI: 10.1038/nchembio775 BindingDB Entry DOI: 10.7270/Q2ZK5GV2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM17292 ((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of New Mexico Health Sciences Center | Assay Description Competitive binding of estrogen to GPR30 and ER alpha were conducted using COS-7 cells transfected with GPR30-GFP or ER alpha-GFP and fluorescent est... | ACS Chem Biol 2: 536-44 (2007) Article DOI: 10.1021/cb700072n BindingDB Entry DOI: 10.7270/Q2V69GXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM50303803 (1-((3aS,4R,9bR)-4-(6-bromobenzo[d][1,3]dioxol-5-yl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh Chemical Diversity Center (UP-CDC) Curated by ChEMBL | Assay Description Inhibition of estrogen binding to GPR30 (unknown origin) | J Med Chem 56: 7161-76 (2013) Article DOI: 10.1021/jm400132d BindingDB Entry DOI: 10.7270/Q2V69M09 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM50303803 (1-((3aS,4R,9bR)-4-(6-bromobenzo[d][1,3]dioxol-5-yl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of New Mexico Health Sciences Center Curated by ChEMBL | Assay Description Displacement of E2-Alexa633 from GFP-tagged GPR30 expressed in COS7 cells by FACS | Nat Chem Biol 2: 207-12 (2006) Article DOI: 10.1038/nchembio775 BindingDB Entry DOI: 10.7270/Q2ZK5GV2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM50590843 (CHEMBL5170710) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2022.114658 BindingDB Entry DOI: 10.7270/Q2NP28CD | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM36493 (E2-NB) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of New Mexico Health Sciences Center | Assay Description Competitive binding of estrogen to GPR30 and ER alpha were conducted using COS-7 cells transfected with GPR30-GFP or ER alpha-GFP and fluorescent est... | ACS Chem Biol 2: 536-44 (2007) Article DOI: 10.1021/cb700072n BindingDB Entry DOI: 10.7270/Q2V69GXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM36492 (E2-NMe3+) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of New Mexico Health Sciences Center | Assay Description Competitive binding of estrogen to GPR30 and ER alpha were conducted using COS-7 cells transfected with GPR30-GFP or ER alpha-GFP and fluorescent est... | ACS Chem Biol 2: 536-44 (2007) Article DOI: 10.1021/cb700072n BindingDB Entry DOI: 10.7270/Q2V69GXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM36490 (E2-NH3+) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of New Mexico Health Sciences Center | Assay Description Competitive binding of estrogen to GPR30 and ER alpha were conducted using COS-7 cells transfected with GPR30-GFP or ER alpha-GFP and fluorescent est... | ACS Chem Biol 2: 536-44 (2007) Article DOI: 10.1021/cb700072n BindingDB Entry DOI: 10.7270/Q2V69GXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM36491 (E2-COO-) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of New Mexico Health Sciences Center | Assay Description Competitive binding of estrogen to GPR30 and ER alpha were conducted using COS-7 cells transfected with GPR30-GFP or ER alpha-GFP and fluorescent est... | ACS Chem Biol 2: 536-44 (2007) Article DOI: 10.1021/cb700072n BindingDB Entry DOI: 10.7270/Q2V69GXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM288677 (US10087191, Example 94) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.0400 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent | Assay Description The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi... | US Patent US10087191 (2018) BindingDB Entry DOI: 10.7270/Q2BP04T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM288659 (US10087191, Example 74) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.210 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent | Assay Description The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi... | US Patent US10087191 (2018) BindingDB Entry DOI: 10.7270/Q2BP04T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM288672 ((E)-3-(3,5-difluoro-4-((1R,3R/1S,3S)-2-(2-fluoro-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.210 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent | Assay Description The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi... | US Patent US10087191 (2018) BindingDB Entry DOI: 10.7270/Q2BP04T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM288680 (US10087191, Example 97) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.240 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent | Assay Description The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi... | US Patent US10087191 (2018) BindingDB Entry DOI: 10.7270/Q2BP04T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM288611 ( (E)-3-(4-((1S,3R)-6-(1-(difluoromethyl)-1H-pyrazo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.290 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent | Assay Description The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi... | US Patent US10087191 (2018) BindingDB Entry DOI: 10.7270/Q2BP04T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM288653 (US10087191, Example 68) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.310 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent | Assay Description The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi... | US Patent US10087191 (2018) BindingDB Entry DOI: 10.7270/Q2BP04T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM288605 ((E)-3-(3,5-difluoro-4-((1S,3R/1R,3S)-2-(2-fluoro-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.320 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent | Assay Description The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi... | US Patent US10087191 (2018) BindingDB Entry DOI: 10.7270/Q2BP04T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM288616 (US10087191, Example 21) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.320 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent | Assay Description The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi... | US Patent US10087191 (2018) BindingDB Entry DOI: 10.7270/Q2BP04T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM288643 (US10087191, Example 57) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.330 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent | Assay Description The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi... | US Patent US10087191 (2018) BindingDB Entry DOI: 10.7270/Q2BP04T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM288673 ((E)-3-(3,5-difluoro-4-((1R,3R/1S,3S)-2-(2-fluoro-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.360 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent | Assay Description The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi... | US Patent US10087191 (2018) BindingDB Entry DOI: 10.7270/Q2BP04T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM288675 ((E)-3-(3,5-difluoro-4-((6S,8R/6R,8S)-(7-isobutyl-8...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.430 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent | Assay Description The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi... | US Patent US10087191 (2018) BindingDB Entry DOI: 10.7270/Q2BP04T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM288658 ((E)-3-(3,5-difluoro-4-((1R,3R/1S,3S)-5-fluoro-2-(2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.450 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent | Assay Description The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi... | US Patent US10087191 (2018) BindingDB Entry DOI: 10.7270/Q2BP04T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM288619 (US10087191, Example 25) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.510 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent | Assay Description The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi... | US Patent US10087191 (2018) BindingDB Entry DOI: 10.7270/Q2BP04T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM288608 ((E)-3-(3,5-difluoro-4-((1S,3R)-2-(2-fluoro-2-methy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.640 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent | Assay Description The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi... | US Patent US10087191 (2018) BindingDB Entry DOI: 10.7270/Q2BP04T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM288684 ((E)-3-(4-((6R,8R/6S,8S)-7-isobutyl-8-methyl-6,7,8,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.640 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent | Assay Description The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi... | US Patent US10087191 (2018) BindingDB Entry DOI: 10.7270/Q2BP04T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM288601 ((E)-3-(3,5-difluoro-4-((1S,3R/1R,3S)-2-(2-fluoro-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.720 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent | Assay Description The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi... | US Patent US10087191 (2018) BindingDB Entry DOI: 10.7270/Q2BP04T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM288602 ((E)-3-(3,5-difluoro-4-((1R,3R/1S,3S)-2-(2-fluoro-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.730 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent | Assay Description The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi... | US Patent US10087191 (2018) BindingDB Entry DOI: 10.7270/Q2BP04T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM288656 (US10087191, Example 71) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.740 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent | Assay Description The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi... | US Patent US10087191 (2018) BindingDB Entry DOI: 10.7270/Q2BP04T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM288655 ((E)-3-(3,5-difluoro-4-((6S,8R/6R,8S)-7-(2-fluoro-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.770 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent | Assay Description The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi... | US Patent US10087191 (2018) BindingDB Entry DOI: 10.7270/Q2BP04T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM288436 ((E)-3-(3,5-difluoro-4-((5S,7R/5R,7S)-6-(2-fluoro-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.770 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent | Assay Description The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi... | US Patent US10087191 (2018) BindingDB Entry DOI: 10.7270/Q2BP04T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM288642 ((E)-3-(3,5-difluoro-4-((1S,3R/1R,3S)-2-(2-fluoro-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.820 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent | Assay Description The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi... | US Patent US10087191 (2018) BindingDB Entry DOI: 10.7270/Q2BP04T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM288644 ((E)-3-(4-((1S,3R/1R,3S)-6-(1-cyclopropyl-1H-pyrazo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.840 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent | Assay Description The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi... | US Patent US10087191 (2018) BindingDB Entry DOI: 10.7270/Q2BP04T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM288681 (US10087191, Example 98) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.850 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent | Assay Description The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi... | US Patent US10087191 (2018) BindingDB Entry DOI: 10.7270/Q2BP04T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM288615 ((E)-3-(4-((1S,3R/1R,3S)-6-(1-ethyl-1H-pyrazol -4-y...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.860 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent | Assay Description The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi... | US Patent US10087191 (2018) BindingDB Entry DOI: 10.7270/Q2BP04T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM288633 ((E)-3-(3,5-difluoro-4-((1S,3R/1R,3S)-5-fluoro-2-(2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.870 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent | Assay Description The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi... | US Patent US10087191 (2018) BindingDB Entry DOI: 10.7270/Q2BP04T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM288650 (US10087191, Example 64) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.07 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent | Assay Description The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi... | US Patent US10087191 (2018) BindingDB Entry DOI: 10.7270/Q2BP04T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM288613 ((E)-3-(4-((1S,3R/1R,3S)-6-(1-ethyl-1H-pyrazol-4-yl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.17 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent | Assay Description The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi... | US Patent US10087191 (2018) BindingDB Entry DOI: 10.7270/Q2BP04T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM288671 ((E)-3-(3,5-difluoro-4-((1R,3R/1S,3S)-2-(2-fluoro-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.22 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent | Assay Description The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi... | US Patent US10087191 (2018) BindingDB Entry DOI: 10.7270/Q2BP04T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM288603 ((E)-3-(3,5-difluoro-4-((1R,3R/1S,3S)-2-(2-fluoro-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.25 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent | Assay Description The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi... | US Patent US10087191 (2018) BindingDB Entry DOI: 10.7270/Q2BP04T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM288607 ((E)-3-(3,5-difluoro-4-((1S,3R/1R,3S)-2-(2-fluoro-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.26 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent | Assay Description The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi... | US Patent US10087191 (2018) BindingDB Entry DOI: 10.7270/Q2BP04T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM288685 ((E)-3-(4-((6S,8R/6R,8S)-7-cyclopentyl-8-methyl-6,7...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.32 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent | Assay Description The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi... | US Patent US10087191 (2018) BindingDB Entry DOI: 10.7270/Q2BP04T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM288612 ((E)-3-(3,5-difluoro-4-((1S,3R/1R,3S)-7-fluoro-2-(2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.36 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent | Assay Description The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi... | US Patent US10087191 (2018) BindingDB Entry DOI: 10.7270/Q2BP04T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM288660 ((E)-3-(4-((1R,3R/1S,3S)-6-(1-ethyl-1H-pyrazol-4-yl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.39 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent | Assay Description The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi... | US Patent US10087191 (2018) BindingDB Entry DOI: 10.7270/Q2BP04T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM288623 ((E)-3-(3,5-difluoro-4-((1S,3R/1R,3S)-2-(2-fluoro-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.45 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent | Assay Description The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi... | US Patent US10087191 (2018) BindingDB Entry DOI: 10.7270/Q2BP04T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM288635 ((E)-3-(4-((1S,3R/1R,3S)-6-(1-ethyl-1H-pyrazol-4-yl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent | Assay Description The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi... | US Patent US10087191 (2018) BindingDB Entry DOI: 10.7270/Q2BP04T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM288614 ((E)-3-(3,5-difluoro-4-((1S,3R/1R,3S)-2-(2-fluoro-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.52 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent | Assay Description The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi... | US Patent US10087191 (2018) BindingDB Entry DOI: 10.7270/Q2BP04T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM288618 ((E)-3-(3,5-difluoro-4-((1S,3R/1R,3S)-2-(2-fluoro-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.59 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent | Assay Description The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi... | US Patent US10087191 (2018) BindingDB Entry DOI: 10.7270/Q2BP04T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM288649 ((E)-3-(3,5-difluoro-4-((1S,3R/1R,3S)-2-(2-fluoro-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent | Assay Description The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi... | US Patent US10087191 (2018) BindingDB Entry DOI: 10.7270/Q2BP04T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM288636 ((E)-3-(3,5-difluoro-4-((1S,3R/1R,3S)-2-(2-fluoro-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.82 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent | Assay Description The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi... | US Patent US10087191 (2018) BindingDB Entry DOI: 10.7270/Q2BP04T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G-protein coupled estrogen receptor 1 (Homo sapiens (Human)) | BDBM288606 (US10087191, Example 8) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.85 | n/a | n/a | n/a | n/a | n/a | n/a |
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd. US Patent | Assay Description The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi... | US Patent US10087191 (2018) BindingDB Entry DOI: 10.7270/Q2BP04T1 | |||||||||||
More data for this Ligand-Target Pair |
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