Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein kinase C alpha type (Homo sapiens (Human)) | BDBM23928 (1,3-dimethoxy-5-[(E)-2-(4-methoxyphenyl)ethenyl]be...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.56E+6 | n/a | n/a | n/a | n/a |
University of Houston Curated by ChEMBL | Assay Description Binding affinity to recombinant C1 domain of PKCalpha expressed in Escherichia coli BL21 (DE3) after 45 mins by fluorescence quenching assay | Bioorg Med Chem 19: 5321-33 (2011) Article DOI: 10.1016/j.bmc.2011.08.008 BindingDB Entry DOI: 10.7270/Q25H7GN9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C alpha type (Homo sapiens (Human)) | BDBM50099066 (CHEMBL279115 | phorbol 13-acetate 12-myristate) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.70E+6 | n/a | n/a | n/a | n/a |
University of Houston Curated by ChEMBL | Assay Description Binding affinity to recombinant C1 domain of PKCalpha expressed in Escherichia coli BL21 (DE3) after 45 mins by fluorescence quenching assay | Bioorg Med Chem 19: 5321-33 (2011) Article DOI: 10.1016/j.bmc.2011.08.008 BindingDB Entry DOI: 10.7270/Q25H7GN9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C alpha type (Homo sapiens (Human)) | BDBM50351474 (CHEMBL1819531) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.98E+6 | n/a | n/a | n/a | n/a |
University of Houston Curated by ChEMBL | Assay Description Binding affinity to recombinant C1 domain of PKCalpha expressed in Escherichia coli BL21 (DE3) after 45 mins by fluorescence quenching assay | Bioorg Med Chem 19: 5321-33 (2011) Article DOI: 10.1016/j.bmc.2011.08.008 BindingDB Entry DOI: 10.7270/Q25H7GN9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C alpha type (Homo sapiens (Human)) | BDBM50351475 (CHEMBL1819528) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 5.04E+6 | n/a | n/a | n/a | n/a |
University of Houston Curated by ChEMBL | Assay Description Binding affinity to recombinant C1 domain of PKCalpha expressed in Escherichia coli BL21 (DE3) after 45 mins by fluorescence quenching assay | Bioorg Med Chem 19: 5321-33 (2011) Article DOI: 10.1016/j.bmc.2011.08.008 BindingDB Entry DOI: 10.7270/Q25H7GN9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase C alpha type (Homo sapiens (Human)) | BDBM23926 ((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 5.78E+6 | n/a | n/a | n/a | n/a |
University of Houston Curated by ChEMBL | Assay Description Binding affinity to recombinant C1 domain of PKCalpha expressed in Escherichia coli BL21 (DE3) after 45 mins by fluorescence quenching assay | Bioorg Med Chem 19: 5321-33 (2011) Article DOI: 10.1016/j.bmc.2011.08.008 BindingDB Entry DOI: 10.7270/Q25H7GN9 | |||||||||||
More data for this Ligand-Target Pair |