Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Thymidylate synthase (Mus musculus) | BDBM50340678![]() (1-(beta-D-2-deoxy-erythro-pentofuranosyl)-5-fluoro...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Thessaly Curated by ChEMBL | Assay Description Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 24 ... | Eur J Med Chem 46: 993-1005 (2011) Article DOI: 10.1016/j.ejmech.2011.01.005 BindingDB Entry DOI: 10.7270/Q2X34XS1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50288983![]() ((S)-2-((S)-4-Carboxy-4-{4-[(2,7-dimethyl-4-oxo-3,4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid UniChem Similars | Article | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for the inhibition of Thymidylate synthase in experiment 1 | Bioorg Med Chem Lett 6: 631-636 (1996) Article DOI: 10.1016/0960-894X(96)00078-9 BindingDB Entry DOI: 10.7270/Q2XS5VC3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50049159![]() ((R)-2-((S)-4-Carboxy-4-{4-[(2,7-dimethyl-4-oxo-3,4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Cancer Research Curated by ChEMBL | Assay Description Inhibition of Thymidylate synthase activity in L1210 cells | J Med Chem 39: 73-85 (1996) Article DOI: 10.1021/jm950471+ BindingDB Entry DOI: 10.7270/Q2WH2P2S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50340678![]() (1-(beta-D-2-deoxy-erythro-pentofuranosyl)-5-fluoro...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Thessaly Curated by ChEMBL | Assay Description Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 4 h... | Eur J Med Chem 46: 993-1005 (2011) Article DOI: 10.1016/j.ejmech.2011.01.005 BindingDB Entry DOI: 10.7270/Q2X34XS1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50288983![]() ((S)-2-((S)-4-Carboxy-4-{4-[(2,7-dimethyl-4-oxo-3,4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid UniChem Similars | Article | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for the inhibition of Thymidylate synthase in experiment 1 | Bioorg Med Chem Lett 6: 631-636 (1996) Article DOI: 10.1016/0960-894X(96)00078-9 BindingDB Entry DOI: 10.7270/Q2XS5VC3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50081273![]() ((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.520 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cells | J Med Chem 42: 3809-20 (1999) BindingDB Entry DOI: 10.7270/Q25M64XD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50049168![]() ((R)-2-((S)-4-Carboxy-4-{4-[(2,7-dimethyl-4-oxo-3,4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.560 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Cancer Research Curated by ChEMBL | Assay Description Inhibition of Thymidylate synthase activity in L1210 cells | J Med Chem 39: 73-85 (1996) Article DOI: 10.1021/jm950471+ BindingDB Entry DOI: 10.7270/Q2WH2P2S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50081256![]() ((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cells | J Med Chem 42: 3809-20 (1999) BindingDB Entry DOI: 10.7270/Q25M64XD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50340678![]() (1-(beta-D-2-deoxy-erythro-pentofuranosyl)-5-fluoro...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Thessaly Curated by ChEMBL | Assay Description Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 15 ... | Eur J Med Chem 46: 993-1005 (2011) Article DOI: 10.1016/j.ejmech.2011.01.005 BindingDB Entry DOI: 10.7270/Q2X34XS1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50340678![]() (1-(beta-D-2-deoxy-erythro-pentofuranosyl)-5-fluoro...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Thessaly Curated by ChEMBL | Assay Description Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 15... | Eur J Med Chem 46: 993-1005 (2011) Article DOI: 10.1016/j.ejmech.2011.01.005 BindingDB Entry DOI: 10.7270/Q2X34XS1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50081259![]() ((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.620 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cells | J Med Chem 42: 3809-20 (1999) BindingDB Entry DOI: 10.7270/Q25M64XD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50340678![]() (1-(beta-D-2-deoxy-erythro-pentofuranosyl)-5-fluoro...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Thessaly Curated by ChEMBL | Assay Description Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 4 ... | Eur J Med Chem 46: 993-1005 (2011) Article DOI: 10.1016/j.ejmech.2011.01.005 BindingDB Entry DOI: 10.7270/Q2X34XS1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50340678![]() (1-(beta-D-2-deoxy-erythro-pentofuranosyl)-5-fluoro...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Thessaly Curated by ChEMBL | Assay Description Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 24... | Eur J Med Chem 46: 993-1005 (2011) Article DOI: 10.1016/j.ejmech.2011.01.005 BindingDB Entry DOI: 10.7270/Q2X34XS1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50288984![]() ((S)-4-[(S)-1-Carboxy-3-(1H-tetrazol-5-yl)-propylca...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 0.820 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for the inhibition of Thymidylate synthase in experiment 1 | Bioorg Med Chem Lett 6: 631-636 (1996) Article DOI: 10.1016/0960-894X(96)00078-9 BindingDB Entry DOI: 10.7270/Q2XS5VC3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50288984![]() ((S)-4-[(S)-1-Carboxy-3-(1H-tetrazol-5-yl)-propylca...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 0.820 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for the inhibition of Thymidylate synthase in experiment 1 | Bioorg Med Chem Lett 6: 631-636 (1996) Article DOI: 10.1016/0960-894X(96)00078-9 BindingDB Entry DOI: 10.7270/Q2XS5VC3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50081265![]() ((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.860 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cells | J Med Chem 42: 3809-20 (1999) BindingDB Entry DOI: 10.7270/Q25M64XD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50288985![]() ((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for the inhibition of Thymidylate synthase. | Bioorg Med Chem Lett 6: 631-636 (1996) Article DOI: 10.1016/0960-894X(96)00078-9 BindingDB Entry DOI: 10.7270/Q2XS5VC3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50081240![]() (2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazolin-6...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cells | J Med Chem 42: 3809-20 (1999) BindingDB Entry DOI: 10.7270/Q25M64XD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50081246![]() ((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cells | J Med Chem 42: 3809-20 (1999) BindingDB Entry DOI: 10.7270/Q25M64XD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50081252![]() ((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cells | J Med Chem 42: 3809-20 (1999) BindingDB Entry DOI: 10.7270/Q25M64XD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50081243![]() (2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazolin-6...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cells | J Med Chem 42: 3809-20 (1999) BindingDB Entry DOI: 10.7270/Q25M64XD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50081260![]() ((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.62 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cells | J Med Chem 42: 3809-20 (1999) BindingDB Entry DOI: 10.7270/Q25M64XD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50081261![]() ((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cells | J Med Chem 42: 3809-20 (1999) BindingDB Entry DOI: 10.7270/Q25M64XD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50107343![]() ((4-Chloro-butyl)-methyl-phosphoramidic acid 5-(5-f...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Thymidylate synthase inhibition in thymidine kinase deficient /TK cells after 2 h treatment | J Med Chem 44: 4475-80 (2001) BindingDB Entry DOI: 10.7270/Q2HM57R4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50081247![]() ((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cells | J Med Chem 42: 3809-20 (1999) BindingDB Entry DOI: 10.7270/Q25M64XD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50049170![]() ((R)-2-((S)-4-Carboxy-4-{4-[(2,7-dimethyl-4-oxo-3,4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Cancer Research Curated by ChEMBL | Assay Description Inhibition of Thymidylate synthase activity in L1210 cells | J Med Chem 39: 73-85 (1996) Article DOI: 10.1021/jm950471+ BindingDB Entry DOI: 10.7270/Q2WH2P2S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50049172![]() ((R)-2-((S)-4-Carboxy-4-{2-fluoro-4-[(2-methyl-4-ox...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Cancer Research Curated by ChEMBL | Assay Description Inhibition of Thymidylate synthase activity in L1210 cells | J Med Chem 39: 73-85 (1996) Article DOI: 10.1021/jm950471+ BindingDB Entry DOI: 10.7270/Q2WH2P2S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50037316![]() ((R)-2-((R)-4-Carboxy-4-{4-[(2-methyl-4-oxo-3,4-dih...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Cancer Research Curated by ChEMBL | Assay Description Tested for inhibition against thymidylate synthase(TS) which is partially purified from L1210 mouse leukemia cells | J Med Chem 37: 3294-302 (1994) BindingDB Entry DOI: 10.7270/Q2QV3N50 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50037303![]() ((R)-2-((R)-4-Carboxy-4-{4-[(2-methyl-4-oxo-3,4-dih...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Cancer Research Curated by ChEMBL | Assay Description Tested for inhibition against thymidylate synthase(TS) which is partially purified from L1210 mouse leukemia cells | J Med Chem 37: 3294-302 (1994) BindingDB Entry DOI: 10.7270/Q2QV3N50 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50081239![]() ((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cells | J Med Chem 42: 3809-20 (1999) BindingDB Entry DOI: 10.7270/Q25M64XD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50081253![]() ((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cells | J Med Chem 42: 3809-20 (1999) BindingDB Entry DOI: 10.7270/Q25M64XD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50049175![]() ((S)-2-((S)-4-Carboxy-4-{4-[(2-methyl-4-oxo-3,4-dih...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Cancer Research Curated by ChEMBL | Assay Description Inhibition of Thymidylate synthase activity in L1210 cells | J Med Chem 39: 73-85 (1996) Article DOI: 10.1021/jm950471+ BindingDB Entry DOI: 10.7270/Q2WH2P2S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50049164![]() ((S)-2-((S)-4-Carboxy-4-{4-[(2-methyl-4-oxo-3,4-dih...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Cancer Research Curated by ChEMBL | Assay Description Inhibition of Thymidylate synthase activity in L1210 cells | J Med Chem 39: 73-85 (1996) Article DOI: 10.1021/jm950471+ BindingDB Entry DOI: 10.7270/Q2WH2P2S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50049176![]() ((R)-2-((S)-4-Carboxy-4-{4-[(2,7-dimethyl-4-oxo-3,4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Cancer Research Curated by ChEMBL | Assay Description Inhibition of Thymidylate synthase activity in L1210 cells | J Med Chem 39: 73-85 (1996) Article DOI: 10.1021/jm950471+ BindingDB Entry DOI: 10.7270/Q2WH2P2S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50081272![]() ((S)-5-Acetylsulfamoyl-2-{4-[(2,7-dimethyl-4-oxo-3,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cells | J Med Chem 42: 3809-20 (1999) BindingDB Entry DOI: 10.7270/Q25M64XD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50081264![]() ((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cells | J Med Chem 42: 3809-20 (1999) BindingDB Entry DOI: 10.7270/Q25M64XD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50081249![]() (2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazolin-6...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cells | J Med Chem 42: 3809-20 (1999) BindingDB Entry DOI: 10.7270/Q25M64XD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50081251![]() ((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cells | J Med Chem 42: 3809-20 (1999) BindingDB Entry DOI: 10.7270/Q25M64XD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50081258![]() (2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazolin-6...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cells | J Med Chem 42: 3809-20 (1999) BindingDB Entry DOI: 10.7270/Q25M64XD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50081262![]() (2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazolin-6...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cells | J Med Chem 42: 3809-20 (1999) BindingDB Entry DOI: 10.7270/Q25M64XD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50037313![]() ((R)-4-((R)-1-Carboxy-ethylcarbamoyl)-2-{2-fluoro-4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Cancer Research Curated by ChEMBL | Assay Description Tested for inhibition against thymidylate synthase(TS) which is partially purified from L1210 mouse leukemia cells | J Med Chem 37: 3294-302 (1994) BindingDB Entry DOI: 10.7270/Q2QV3N50 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50081248![]() ((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4.40 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cells | J Med Chem 42: 3809-20 (1999) BindingDB Entry DOI: 10.7270/Q25M64XD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50033933![]() ((R)-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazolin...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Zeneca Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of thymidylate synthase purified from mouse L1210 leukemia cells that overproduce thymidylate synthase (TS) | J Med Chem 38: 994-1004 (1995) BindingDB Entry DOI: 10.7270/Q2J67FZ7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50049167![]() ((R)-2-((S)-4-Carboxy-4-{4-[(2,7-dimethyl-4-oxo-3,4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Cancer Research Curated by ChEMBL | Assay Description Inhibition of Thymidylate synthase activity in L1210 cells | J Med Chem 39: 73-85 (1996) Article DOI: 10.1021/jm950471+ BindingDB Entry DOI: 10.7270/Q2WH2P2S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50049165![]() ((R)-2-((S)-4-Carboxy-4-{4-[(2-methyl-4-oxo-3,4-dih...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Cancer Research Curated by ChEMBL | Assay Description Inhibition of Thymidylate synthase activity in L1210 cells | J Med Chem 39: 73-85 (1996) Article DOI: 10.1021/jm950471+ BindingDB Entry DOI: 10.7270/Q2WH2P2S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50049165![]() ((R)-2-((S)-4-Carboxy-4-{4-[(2-methyl-4-oxo-3,4-dih...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid UniChem Similars | Article | n/a | n/a | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for the inhibition of Thymidylate synthase. | Bioorg Med Chem Lett 6: 631-636 (1996) Article DOI: 10.1016/0960-894X(96)00078-9 BindingDB Entry DOI: 10.7270/Q2XS5VC3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50081266![]() ((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5.20 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cells | J Med Chem 42: 3809-20 (1999) BindingDB Entry DOI: 10.7270/Q25M64XD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50081241![]() (2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazolin-6...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5.40 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cells | J Med Chem 42: 3809-20 (1999) BindingDB Entry DOI: 10.7270/Q25M64XD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50081267![]() (2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazolin-6...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5.40 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cells | J Med Chem 42: 3809-20 (1999) BindingDB Entry DOI: 10.7270/Q25M64XD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidylate synthase (Mus musculus) | BDBM50081271![]() ((S)-2-{4-[(2,7-Dimethyl-4-oxo-3,4-dihydro-quinazol...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5.60 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca Curated by ChEMBL | Assay Description Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cells | J Med Chem 42: 3809-20 (1999) BindingDB Entry DOI: 10.7270/Q25M64XD | |||||||||||
More data for this Ligand-Target Pair |
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