Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Alpha-synuclein (Homo sapiens (Human)) | BDBM50614057![]() (CHEMBL5286894) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM50389294![]() (CHEMBL2063787) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 134 | n/a | n/a | n/a | n/a | n/a | n/a |
Washington University School of Medicine Curated by ChEMBL | Assay Description Binding affinity to human alpha-synuclein expressed in Escherichia coli BL21 (DE3) cells after 1 hr by thioflavin T fluorescence assay | Bioorg Med Chem 20: 4625-34 (2012) Article DOI: 10.1016/j.bmc.2012.06.023 BindingDB Entry DOI: 10.7270/Q25B03J1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM50092056![]() ((2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclo...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of alpha-synuclein fibril formation (unknown origin) incubated for 24 hrs to 7 days by thioflavin S based fluorescence assay | Citation and Details Article DOI: 10.1016/j.ejmech.2019.01.045 BindingDB Entry DOI: 10.7270/Q2H998V9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM50553255![]() (All-Trans-Retinal | CHEBI:17898 | Retinal) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE KEGG PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of alpha-synuclein fibril formation (unknown origin) incubated for 24 hrs to 7 days by thioflavin S based fluorescence assay | Citation and Details Article DOI: 10.1016/j.ejmech.2019.01.045 BindingDB Entry DOI: 10.7270/Q2H998V9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM50389304![]() (CHEMBL2063797) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 204 | n/a | n/a | n/a | n/a | n/a | n/a |
Washington University School of Medicine Curated by ChEMBL | Assay Description Binding affinity to human alpha-synuclein expressed in Escherichia coli BL21 (DE3) cells after 1 hr by thioflavin T fluorescence assay | Bioorg Med Chem 20: 4625-34 (2012) Article DOI: 10.1016/j.bmc.2012.06.023 BindingDB Entry DOI: 10.7270/Q25B03J1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM32020![]() (4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyro...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of alpha-synuclein aggregation (unknown origin) incubated for 8 days by thioflavin S based fluorescence assay | Citation and Details Article DOI: 10.1016/j.ejmech.2019.01.045 BindingDB Entry DOI: 10.7270/Q2H998V9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM50133496![]() ((2R)-3-(3,4-dihydroxyphenyl)-2-[(2E)-3-(3,4-dihydr...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of alpha-synuclein fibril formation (unknown origin) incubated for 24 hrs to 7 days by thioflavin S based fluorescence assay | Citation and Details Article DOI: 10.1016/j.ejmech.2019.01.045 BindingDB Entry DOI: 10.7270/Q2H998V9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM50140172![]() (CHEBI:3962 | CHEMBL140 | Curcumin | US9409845, Tab...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of alpha-synuclein fibril formation (unknown origin) incubated for 24 hrs to 7 days by thioflavin S based fluorescence assay | Citation and Details Article DOI: 10.1016/j.ejmech.2019.01.045 BindingDB Entry DOI: 10.7270/Q2H998V9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM15236![]() (3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chr...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of alpha-synuclein fibril formation (unknown origin) incubated for 24 hrs to 7 days by thioflavin S based fluorescence assay | Citation and Details Article DOI: 10.1016/j.ejmech.2019.01.045 BindingDB Entry DOI: 10.7270/Q2H998V9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM32020![]() (4-[4-(3,4-dihydroxyphenyl)-2,3-dimethyl-butyl]pyro...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of alpha-synuclein fibril formation (unknown origin) incubated for 24 hrs to 7 days by thioflavin S based fluorescence assay | Citation and Details Article DOI: 10.1016/j.ejmech.2019.01.045 BindingDB Entry DOI: 10.7270/Q2H998V9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM50389305![]() (CHEMBL2063798) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 241 | n/a | n/a | n/a | n/a | n/a | n/a |
Washington University School of Medicine Curated by ChEMBL | Assay Description Binding affinity to human alpha-synuclein expressed in Escherichia coli BL21 (DE3) cells after 1 hr by thioflavin T fluorescence assay | Bioorg Med Chem 20: 4625-34 (2012) Article DOI: 10.1016/j.bmc.2012.06.023 BindingDB Entry DOI: 10.7270/Q25B03J1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM50553254![]() (CHEMBL4787961) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of alpha-synuclein fibril formation (unknown origin) incubated for 24 hrs to 7 days by thioflavin S based fluorescence assay | Citation and Details Article DOI: 10.1016/j.ejmech.2019.01.045 BindingDB Entry DOI: 10.7270/Q2H998V9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM510815![]() (N-(1-(1H-Indol-3-yl)hexan-2- yl)-2-(piperazin-1-yl...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we... | Citation and Details BindingDB Entry DOI: 10.7270/Q2NV9NDS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM15579![]() (CHEMBL972 | DEPRENYL | L-Deprenyl | N-methyl-N-[(2...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of alpha-synuclein fibril formation (unknown origin) incubated for 6 days by thioflavin S based fluorescence assay | Citation and Details Article DOI: 10.1016/j.ejmech.2019.01.045 BindingDB Entry DOI: 10.7270/Q2H998V9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM50389295![]() (CHEMBL2063788) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 314 | n/a | n/a | n/a | n/a | n/a | n/a |
Washington University School of Medicine Curated by ChEMBL | Assay Description Binding affinity to human alpha-synuclein expressed in Escherichia coli BL21 (DE3) cells after 1 hr by thioflavin T fluorescence assay | Bioorg Med Chem 20: 4625-34 (2012) Article DOI: 10.1016/j.bmc.2012.06.023 BindingDB Entry DOI: 10.7270/Q25B03J1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM510819![]() (N-(1-(1H-Indol-3-yl)hexan-2- yl)-5-(4-methylpipera...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we... | Citation and Details BindingDB Entry DOI: 10.7270/Q2NV9NDS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM510818![]() (N-(1-(1H-Indol-3-yl)hexan-2- yl)-2-(4-methylpipera...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 390 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we... | Citation and Details BindingDB Entry DOI: 10.7270/Q2NV9NDS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM510822![]() ((S)-N-(1-(1H-Indol-3-yl)hexan- 2-yl)-2-(4-methylpi...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | MCE PC cid PC sid UniChem | US Patent | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we... | Citation and Details BindingDB Entry DOI: 10.7270/Q2NV9NDS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM481754![]() (N-[1-(1H-indol-3- ylmethyl)pentyl]-2-(4- phenylpip...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem | US Patent | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Biopharma SRL US Patent | Assay Description The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we... | US Patent US10913735 (2021) BindingDB Entry DOI: 10.7270/Q25Q507F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM50389296![]() (CHEMBL2063789) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 442 | n/a | n/a | n/a | n/a | n/a | n/a |
Washington University School of Medicine Curated by ChEMBL | Assay Description Binding affinity to human alpha-synuclein expressed in Escherichia coli BL21 (DE3) cells after 1 hr by thioflavin T fluorescence assay | Bioorg Med Chem 20: 4625-34 (2012) Article DOI: 10.1016/j.bmc.2012.06.023 BindingDB Entry DOI: 10.7270/Q25B03J1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM50389291![]() (CHEMBL1976750) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 485 | n/a | n/a | n/a | n/a | n/a | n/a |
Washington University School of Medicine Curated by ChEMBL | Assay Description Binding affinity to human alpha-synuclein expressed in Escherichia coli BL21 (DE3) cells after 1 hr by thioflavin T fluorescence assay | Bioorg Med Chem 20: 4625-34 (2012) Article DOI: 10.1016/j.bmc.2012.06.023 BindingDB Entry DOI: 10.7270/Q25B03J1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM50389292![]() (CHEMBL2063785) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 507 | n/a | n/a | n/a | n/a | n/a | n/a |
Washington University School of Medicine Curated by ChEMBL | Assay Description Binding affinity to human alpha-synuclein expressed in Escherichia coli BL21 (DE3) cells after 1 hr by thioflavin T fluorescence assay | Bioorg Med Chem 20: 4625-34 (2012) Article DOI: 10.1016/j.bmc.2012.06.023 BindingDB Entry DOI: 10.7270/Q25B03J1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM55121![]() (3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 530 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of alpha-synuclein fibril formation (unknown origin) incubated for 6 days by thioflavin S based fluorescence assay | Citation and Details Article DOI: 10.1016/j.ejmech.2019.01.045 BindingDB Entry DOI: 10.7270/Q2H998V9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM510823![]() ((R)-N-(1-(1H-Indol-3-yl)hexan- 2-yl)-2-(4-methylpi...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem | US Patent | n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we... | Citation and Details BindingDB Entry DOI: 10.7270/Q2NV9NDS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM50214744![]() ((2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic aci...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of alpha-synuclein fibril formation (unknown origin) incubated for 24 hrs to 7 days by thioflavin S based fluorescence assay | Citation and Details Article DOI: 10.1016/j.ejmech.2019.01.045 BindingDB Entry DOI: 10.7270/Q2H998V9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM510820![]() (N-(1-(1H-Indol-3-yl)hexan-2- yl)-5-(4-methylpipera...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 770 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we... | Citation and Details BindingDB Entry DOI: 10.7270/Q2NV9NDS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM481757![]() (N-[1-(1H-indol-3- ylmethyl)pentyl]-2-[4-(1- methyl...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Biopharma SRL US Patent | Assay Description The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we... | US Patent US10913735 (2021) BindingDB Entry DOI: 10.7270/Q25Q507F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM23417![]() (α-CA inhibitor, 4 | (-)-Epicatechin | (2R,3R)...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of alpha-synuclein fibril formation (unknown origin) incubated for 24 hrs to 7 days by thioflavin S based fluorescence assay | Citation and Details Article DOI: 10.1016/j.ejmech.2019.01.045 BindingDB Entry DOI: 10.7270/Q2H998V9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM491842![]() (N-(1-(1H-indol-3- yl)hexan-2-yl)- 2-(4-isobutyl- p...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Biopharma SRL US Patent | Assay Description The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we... | US Patent US10975066 (2021) BindingDB Entry DOI: 10.7270/Q26W9F6X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM481758![]() (N-[1-(1H-indol-3- ylmethyl)pentyl]-2-[4-(2- methyl...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Biopharma SRL US Patent | Assay Description The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we... | US Patent US10913735 (2021) BindingDB Entry DOI: 10.7270/Q25Q507F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM481749![]() (N-[1-(1H-indol-3- ylmethyl)pentyl]-2-[4-(2- pyridy...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Biopharma SRL US Patent | Assay Description The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we... | US Patent US10913735 (2021) BindingDB Entry DOI: 10.7270/Q25Q507F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM50544150![]() (CHEMBL4641523) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 980 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University Curated by ChEMBL | Assay Description Inhibition of alpha-synuclein (unknown origin) aggregation incubated for 3 days by thioflavin T based fluorescence assay | Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115596 BindingDB Entry DOI: 10.7270/Q2ST7TD0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM491847![]() (N-(1-(1H-indol-3- yl)hexan-2-yl)-2- (4-(3,3,3-trif...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Biopharma SRL US Patent | Assay Description The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we... | US Patent US10975066 (2021) BindingDB Entry DOI: 10.7270/Q26W9F6X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM491846![]() (N-(1-(1H-indol-3- yl)hexan-2-yl)-2- (4-(2,2,2-trif...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Biopharma SRL US Patent | Assay Description The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we... | US Patent US10975066 (2021) BindingDB Entry DOI: 10.7270/Q26W9F6X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM481756![]() (N-[1-(1H-indol-3- ylmethyl)pentyl]-2-[4-(1H- pyraz...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Biopharma SRL US Patent | Assay Description The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we... | US Patent US10913735 (2021) BindingDB Entry DOI: 10.7270/Q25Q507F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM481745![]() (N-[1-(1H-indol-3- ylmethyl)pentyl]-2-(4- pyrimidin...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Biopharma SRL US Patent | Assay Description The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we... | US Patent US10913735 (2021) BindingDB Entry DOI: 10.7270/Q25Q507F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM481747![]() (N-[1-(1H-indol-3- ylmethyl)pentyl]-2-[4-(3- pyridy...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Biopharma SRL US Patent | Assay Description The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we... | US Patent US10913735 (2021) BindingDB Entry DOI: 10.7270/Q25Q507F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM50510750![]() (CHEMBL4551721) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.09E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University Curated by ChEMBL | Assay Description Inhibition of alpha-synuclein aggregation (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 3 days by thioflavin T fluorescence... | Bioorg Med Chem 27: 3089-3096 (2019) Article DOI: 10.1016/j.bmc.2019.05.032 BindingDB Entry DOI: 10.7270/Q290274V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM491840![]() (N-(1-(1H-indol-3- yl)hexan-2-yl)-2- (4-cyclopropyl...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Biopharma SRL US Patent | Assay Description The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we... | US Patent US10975066 (2021) BindingDB Entry DOI: 10.7270/Q26W9F6X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM491843![]() (N-(1-(1H-indol-3- yl)hexan-2-yl)- 2-(4-(2-methoxy-...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Biopharma SRL US Patent | Assay Description The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we... | US Patent US10975066 (2021) BindingDB Entry DOI: 10.7270/Q26W9F6X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM481755![]() (N-[1-(1H-indol-3- ylmethyl)pentyl]-2-[4-(1H- pyraz...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Biopharma SRL US Patent | Assay Description The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we... | US Patent US10913735 (2021) BindingDB Entry DOI: 10.7270/Q25Q507F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM481750![]() (N-[1-(1H-indol-3- ylmethyl)pentyl]-2-(4- pyrimidin...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Biopharma SRL US Patent | Assay Description The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we... | US Patent US10913735 (2021) BindingDB Entry DOI: 10.7270/Q25Q507F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM491859![]() (US10975066, Example 24) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Biopharma SRL US Patent | Assay Description The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we... | US Patent US10975066 (2021) BindingDB Entry DOI: 10.7270/Q26W9F6X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM491845![]() (N-(1-(1H-indol-3- yl)hexan-2-yl)-2- (4-(2,2-difluo...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Biopharma SRL US Patent | Assay Description The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we... | US Patent US10975066 (2021) BindingDB Entry DOI: 10.7270/Q26W9F6X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM491839![]() (N-(1-(1H-indol-3- yl)hexan-2-yl)-2-(4- isopropylpi...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Biopharma SRL US Patent | Assay Description The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we... | US Patent US10975066 (2021) BindingDB Entry DOI: 10.7270/Q26W9F6X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM491844![]() (N-(1-(1H-indol-3- yl)hexan-2-yl)-2- (4-(2-fluoroet...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Biopharma SRL US Patent | Assay Description The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we... | US Patent US10975066 (2021) BindingDB Entry DOI: 10.7270/Q26W9F6X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM481753![]() (N-[1-(1H-indol-3- ylmethyl)pentyl]-2-(4- pyrazin-2...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Biopharma SRL US Patent | Assay Description The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we... | US Patent US10913735 (2021) BindingDB Entry DOI: 10.7270/Q25Q507F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM491850![]() (N-(1-(1H-indol- 3-yl)hexan-2-yl)- 2-(cis-3,4,5- tr...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Biopharma SRL US Patent | Assay Description The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we... | US Patent US10975066 (2021) BindingDB Entry DOI: 10.7270/Q26W9F6X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM491853![]() (N-(2-(1H-indol-3- yl)ethyl)-N-butyl- 2-(4-methyl- ...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
UCB Biopharma SRL US Patent | Assay Description The fluorescence polarization assay tests the ability of compounds to inhibit the self-aggregation of α-synuclein peptide fragments. Peptides we... | US Patent US10975066 (2021) BindingDB Entry DOI: 10.7270/Q26W9F6X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-synuclein (Homo sapiens (Human)) | BDBM50544151![]() (CHEMBL4640362) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.22E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University Curated by ChEMBL | Assay Description Inhibition of alpha-synuclein (unknown origin) aggregation incubated for 3 days by thioflavin T based fluorescence assay | Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115596 BindingDB Entry DOI: 10.7270/Q2ST7TD0 | |||||||||||
More data for this Ligand-Target Pair |
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