Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM50083722![]() (CHEMBL3423198) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds Curated by ChEMBL | Assay Description Inhibition of thrombin-activated F13-A (unknown origin) in plasma assessed as inhibition of fibrin clot formation after 7 mins by biotin incorporatio... | Eur J Med Chem 98: 49-53 (2015) Article DOI: 10.1016/j.ejmech.2015.05.019 BindingDB Entry DOI: 10.7270/Q261121G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM50083725![]() (CHEMBL3423195) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds Curated by ChEMBL | Assay Description Inhibition of thrombin-activated F13-A (unknown origin) in plasma assessed as inhibition of fibrin clot formation after 7 mins by biotin incorporatio... | Eur J Med Chem 98: 49-53 (2015) Article DOI: 10.1016/j.ejmech.2015.05.019 BindingDB Entry DOI: 10.7270/Q261121G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577509![]() (US11472838, Compound 27 | US11472838, Compound 31a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM50245478![]() (CHEMBL4081588 | US11472838, Compound Ref. 25) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577546![]() (US11472838, Compound Ref. 21) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | >10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577540![]() (US11472838, Compound Ref. 16) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | >10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577537![]() (US11472838, Compound Ref. 14) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | >10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577484![]() (US11472838, Compound 1a/b) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577511![]() (US11472838, Compound 29 | US11472838, Compound 32a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577487![]() (US11472838, Compound 4) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577512![]() (US11472838, Compound 30) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577483![]() (US11472838, Compound 5) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577483![]() (US11472838, Compound 5) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577485![]() (US11472838, Compound 2a/b) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577488![]() (US11472838, Compound 6) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577506![]() (US11472838, Compound 24a/b) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577507![]() (US11472838, Compound 25a/b) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577486![]() (US11472838, Compound 3) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577489![]() (US11472838, Compound 7a/b) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577490![]() (US11472838, Compound 8a/b) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577483![]() (US11472838, Compound 5) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The most relevant off-targets are the transglutaminase isoenzymes especially tissue transglutaminase (TG2) because the enzyme is ubiquitously express... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577483![]() (US11472838, Compound 5) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description The most relevant off-targets are the transglutaminase isoenzymes especially tissue transglutaminase (TG2) because the enzyme is ubiquitously express... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577511![]() (US11472838, Compound 29 | US11472838, Compound 32a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577496![]() (US11472838, Compound 14a/b) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain [Q652E] (Homo sapiens (Human)) | BDBM50608714![]() (CHEMBL5281897) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577509![]() (US11472838, Compound 27 | US11472838, Compound 31a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain [Q652E] (Homo sapiens (Human)) | BDBM50608719![]() (CHEMBL5269766) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577547![]() (US11472838, Compound 45a/b) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577510![]() (US11472838, Compound 28) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577530![]() (US11472838, Compound 39a/b) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 39 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM50420503![]() (CHEMBL2086505) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 39 | n/a | n/a | n/a | n/a | n/a | n/a |
Evotec (UK) Ltd. Curated by ChEMBL | Assay Description Inhibition of thrombin activated human F13a by fluorescent transamidation assay | J Med Chem 55: 1021-46 (2012) Article DOI: 10.1021/jm201310y BindingDB Entry DOI: 10.7270/Q2CN7560 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577499![]() (US11472838, Compound 17a/b) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577518![]() (US11472838, Compound 36a/b) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577504![]() (US11472838, Compound 22a/b) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577492![]() (US11472838, Compound 10a/b) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577508![]() (US11472838, Compound 26a/b) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 43 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577528![]() (US11472838, Compound 38) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM50083726![]() (CHEMBL3423194) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds Curated by ChEMBL | Assay Description Inhibition of thrombin-activated F13-A (unknown origin) in plasma assessed as inhibition of fibrin clot formation after 7 mins by biotin incorporatio... | Eur J Med Chem 98: 49-53 (2015) Article DOI: 10.1016/j.ejmech.2015.05.019 BindingDB Entry DOI: 10.7270/Q261121G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577494![]() (US11472838, Compound 12a/b) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM50420457![]() (CHEMBL2086890) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
Evotec (UK) Ltd. Curated by ChEMBL | Assay Description Inhibition of thrombin activated human F13a by fluorescent transamidation assay | J Med Chem 55: 1021-46 (2012) Article DOI: 10.1021/jm201310y BindingDB Entry DOI: 10.7270/Q2CN7560 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM50083728![]() (CHEMBL3423193) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds Curated by ChEMBL | Assay Description Inhibition of thrombin-activated F13-A (unknown origin) in plasma assessed as inhibition of fibrin clot formation after 7 mins by biotin incorporatio... | Eur J Med Chem 98: 49-53 (2015) Article DOI: 10.1016/j.ejmech.2015.05.019 BindingDB Entry DOI: 10.7270/Q261121G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577534![]() (US11472838, Compound 42a/b) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 56 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577549![]() (US11472838, Compound Ref. 23) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 56 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577503![]() (US11472838, Compound 21a/b) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM50420458![]() (CHEMBL2086891) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 66 | n/a | n/a | n/a | n/a | n/a | n/a |
Evotec (UK) Ltd. Curated by ChEMBL | Assay Description Inhibition of thrombin activated human F13a by fluorescent transamidation assay | J Med Chem 55: 1021-46 (2012) Article DOI: 10.1021/jm201310y BindingDB Entry DOI: 10.7270/Q2CN7560 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577497![]() (US11472838, Compound 15a/b) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 69 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577519![]() (US11472838, Compound 37a/b) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 69 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577493![]() (US11472838, Compound 11a/b) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577532![]() (US11472838, Compound 40) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 81 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor XIII A chain (Homo sapiens (Human)) | BDBM577517![]() (US11472838, Compound 35a/b) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 86 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description FXIIIa activity has been determined using substrate A101 (Zedira GmbH, Darmstadt, Germany), which is based on the N-terminal dodecapeptide of α2... | Citation and Details BindingDB Entry DOI: 10.7270/Q2WW7MZ9 | |||||||||||
More data for this Ligand-Target Pair |
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