Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium/potassium-transporting ATPase subunit alpha-2/beta-2 (Homo sapiens (Human)) | BDBM444991![]() (US10668094, Compound DMDMcB-(cyclic)) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 5.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yeda Research and Development Co. Ltd. US Patent | Assay Description To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo... | US Patent US10668094 (2020) BindingDB Entry DOI: 10.7270/Q2FX7DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-2/beta-2 (Homo sapiens (Human)) | BDBM444840![]() (US10668094, Compound DcB-(cyclic) | US10668094, Co...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 5.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yeda Research and Development Co. Ltd. US Patent | Assay Description To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo... | US Patent US10668094 (2020) BindingDB Entry DOI: 10.7270/Q2FX7DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-2/beta-2 (Homo sapiens (Human)) | BDBM444975![]() (US10668094, Compound DMcP-(cyclic) | US10668094, C...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 5.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yeda Research and Development Co. Ltd. US Patent | Assay Description To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo... | US Patent US10668094 (2020) BindingDB Entry DOI: 10.7270/Q2FX7DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-2/beta-2 (Homo sapiens (Human)) | BDBM444840![]() (US10668094, Compound DcB-(cyclic) | US10668094, Co...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yeda Research and Development Co. Ltd. US Patent | Assay Description To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo... | US Patent US10668094 (2020) BindingDB Entry DOI: 10.7270/Q2FX7DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-2/beta-2 (Homo sapiens (Human)) | BDBM444983![]() (US10668094, Compound DBz-(cyclic)) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 6.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yeda Research and Development Co. Ltd. US Patent | Assay Description To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo... | US Patent US10668094 (2020) BindingDB Entry DOI: 10.7270/Q2FX7DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-2/beta-2 (Homo sapiens (Human)) | BDBM444975![]() (US10668094, Compound DMcP-(cyclic) | US10668094, C...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yeda Research and Development Co. Ltd. US Patent | Assay Description To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo... | US Patent US10668094 (2020) BindingDB Entry DOI: 10.7270/Q2FX7DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-2/beta-2 (Homo sapiens (Human)) | BDBM444977![]() (US10668094, Compound DiB) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yeda Research and Development Co. Ltd. US Patent | Assay Description To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo... | US Patent US10668094 (2020) BindingDB Entry DOI: 10.7270/Q2FX7DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-2/beta-2 (Homo sapiens (Human)) | BDBM444989![]() (US10668094, Compound DP) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 10.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yeda Research and Development Co. Ltd. US Patent | Assay Description To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo... | US Patent US10668094 (2020) BindingDB Entry DOI: 10.7270/Q2FX7DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-2/beta-2 (Homo sapiens (Human)) | BDBM444981![]() (US10668094, Compound DEcP-(cyclic)) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 12.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yeda Research and Development Co. Ltd. US Patent | Assay Description To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo... | US Patent US10668094 (2020) BindingDB Entry DOI: 10.7270/Q2FX7DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-2/beta-2 (Homo sapiens (Human)) | BDBM444980![]() (US10668094, Compound DcP-(cyclic)) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yeda Research and Development Co. Ltd. US Patent | Assay Description To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo... | US Patent US10668094 (2020) BindingDB Entry DOI: 10.7270/Q2FX7DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-2/beta-2 (Homo sapiens (Human)) | BDBM444994![]() (US10668094, Compound DTMS-(silyl)) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 14.3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yeda Research and Development Co. Ltd. US Patent | Assay Description To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo... | US Patent US10668094 (2020) BindingDB Entry DOI: 10.7270/Q2FX7DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-2/beta-2 (Homo sapiens (Human)) | BDBM444984![]() (US10668094, Compound DcH-(cyclic)) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 15.3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yeda Research and Development Co. Ltd. US Patent | Assay Description To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo... | US Patent US10668094 (2020) BindingDB Entry DOI: 10.7270/Q2FX7DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-2/beta-2 (Homo sapiens (Human)) | BDBM231661![]() (DEt (12) | US10668094, Compound DEt) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 16.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yeda Research and Development Co. Ltd. US Patent | Assay Description To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo... | US Patent US10668094 (2020) BindingDB Entry DOI: 10.7270/Q2FX7DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-2/beta-2 (Homo sapiens (Human)) | BDBM444979![]() (US10668094, Compound DiP) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 16.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yeda Research and Development Co. Ltd. US Patent | Assay Description To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo... | US Patent US10668094 (2020) BindingDB Entry DOI: 10.7270/Q2FX7DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-2/beta-2 (Homo sapiens (Human)) | BDBM231662![]() (DMeCF3 (13) | US10668094, Compound DCF3) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 18.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yeda Research and Development Co. Ltd. US Patent | Assay Description To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo... | US Patent US10668094 (2020) BindingDB Entry DOI: 10.7270/Q2FX7DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-2/beta-2 (Homo sapiens (Human)) | BDBM444990![]() (US10668094, Compound DtB) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 18.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yeda Research and Development Co. Ltd. US Patent | Assay Description To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo... | US Patent US10668094 (2020) BindingDB Entry DOI: 10.7270/Q2FX7DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-2/beta-2 (Homo sapiens (Human)) | BDBM231660![]() (DMe (11) | US10668094, Compound DMe) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 20.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yeda Research and Development Co. Ltd. US Patent | Assay Description To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo... | US Patent US10668094 (2020) BindingDB Entry DOI: 10.7270/Q2FX7DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-2/beta-2 (Homo sapiens (Human)) | BDBM444978![]() (US10668094, Compound DESA-(sulfonamide)) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 31.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yeda Research and Development Co. Ltd. US Patent | Assay Description To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo... | US Patent US10668094 (2020) BindingDB Entry DOI: 10.7270/Q2FX7DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-2/beta-2 (Homo sapiens (Human)) | BDBM444976![]() (US10668094, Compound DESM-(sulfonyl)) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 31.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yeda Research and Development Co. Ltd. US Patent | Assay Description To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo... | US Patent US10668094 (2020) BindingDB Entry DOI: 10.7270/Q2FX7DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-2/beta-2 (Homo sapiens (Human)) | BDBM444996![]() (US10668094, Compound DcPe-(cyclic)) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 33.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yeda Research and Development Co. Ltd. US Patent | Assay Description To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo... | US Patent US10668094 (2020) BindingDB Entry DOI: 10.7270/Q2FX7DH9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-2/beta-2 (Homo sapiens (Human)) | BDBM46356![]() (DIGITOXIN | MLS000069787 | SMR000058529 | US106680...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB US Patent | 40.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yeda Research and Development Co. Ltd. US Patent | Assay Description To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo... | US Patent US10668094 (2020) BindingDB Entry DOI: 10.7270/Q2FX7DH9 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-2/beta-2 (Homo sapiens (Human)) | BDBM46355![]() (DIGOXIN | MLS000069819 | SMR000059217 | US10668094...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars | PDB US Patent | 58 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yeda Research and Development Co. Ltd. US Patent | Assay Description To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo... | US Patent US10668094 (2020) BindingDB Entry DOI: 10.7270/Q2FX7DH9 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-2/beta-2 (Homo sapiens (Human)) | BDBM444982![]() (US10668094, Compound DMSM-(sulfonyl)) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 123 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yeda Research and Development Co. Ltd. US Patent | Assay Description To screen for isoform selectivity of the digoxin derivatives we compared inhibition of Na,K-ATPase activity of purified detergent-soluble human isofo... | US Patent US10668094 (2020) BindingDB Entry DOI: 10.7270/Q2FX7DH9 | |||||||||||
More data for this Ligand-Target Pair |