Compile Data Set for Download or QSAR

Found 144 hits Enz. Inhib. hit(s) with all data for entry = 7697   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50242957 (CHEMBL4100451) Show SMILES N[C@@H]1CCCN(C1)C(=O)c1cc(OC[C@H]2CCC(=O)N2)n(n1)-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C21H24N6O3/c22-11-14-3-6-17(7-4-14)27-20(30-13-16-5-8-19(28)24-16)10-18(25-27)21(29)26-9-1-2-15(23)12-26/h3-4,6-7,10,15-16H,1-2,5,8-9,12-13,23H2,(H,24,28)/t15-,16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli using Histone H3(1 to 21)K4(Me1) biotin...				Bioorg Med Chem Lett 27: 3190-3195 (2017) Article DOI: 10.1016/j.bmcl.2017.05.018 BindingDB Entry DOI: 10.7270/Q2M047W8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50241492 (CHEMBL4063384) Show SMILES CC(=O)N1CCc2cc(ccc12)S(=O)(=O)N(CC(=O)N1CCC(N)CC1)c1ccc(cc1)C#N Show InChI InChI=1S/C24H27N5O4S/c1-17(30)28-13-8-19-14-22(6-7-23(19)28)34(32,33)29(21-4-2-18(15-25)3-5-21)16-24(31)27-11-9-20(26)10-12-27/h2-7,14,20H,8-13,16,26H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Inhibition of [3H]3-beta-(p-fluorophenyl)tropane-2beta-carboxylic acid methyl ester binding to Dopamine transporter in rat striatal membranes.				J Med Chem 60: 7984-7999 (2017) Article DOI: 10.1021/acs.jmedchem.7b00462 BindingDB Entry DOI: 10.7270/Q2M32XX8
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50242954 (CHEMBL4101067) Show SMILES CCc1cc(COc2cc(nn2-c2ccc(cc2)C#N)C(=O)N2CCC[C@@H](N)C2)on1 |r| Show InChI InChI=1S/C22H24N6O3/c1-2-17-10-19(31-26-17)14-30-21-11-20(22(29)27-9-3-4-16(24)13-27)25-28(21)18-7-5-15(12-23)6-8-18/h5-8,10-11,16H,2-4,9,13-14,24H2,1H3/t16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Inhibition of human ERG by patch clamp assay				Bioorg Med Chem Lett 27: 3190-3195 (2017) Article DOI: 10.1016/j.bmcl.2017.05.018 BindingDB Entry DOI: 10.7270/Q2M047W8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50241507 (CHEMBL4083732) Show SMILES Cc1ccc(cc1)S(=O)(=O)N(CC(=O)N1CCC(C)(N)CC1)c1ccc(cc1)C#N Show InChI InChI=1S/C22H26N4O3S/c1-17-3-9-20(10-4-17)30(28,29)26(19-7-5-18(15-23)6-8-19)16-21(27)25-13-11-22(2,24)12-14-25/h3-10H,11-14,16,24H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Inhibition of N-terminal truncated human LSD1 (151 to 852 residues) expressed in Escherichia coli after 30 mins using histone H3(1-21)K4(Me1) biotin ...				J Med Chem 60: 7984-7999 (2017) Article DOI: 10.1021/acs.jmedchem.7b00462 BindingDB Entry DOI: 10.7270/Q2M32XX8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50241502 (CHEMBL4093998) Show SMILES CC(=O)N1CCc2cc(ccc12)S(=O)(=O)N(CC(=O)N1CCC[C@@H](N)C1)c1ccc(cc1)C#N |r| Show InChI InChI=1S/C24H27N5O4S/c1-17(30)28-12-10-19-13-22(8-9-23(19)28)34(32,33)29(21-6-4-18(14-25)5-7-21)16-24(31)27-11-2-3-20(26)15-27/h4-9,13,20H,2-3,10-12,15-16,26H2,1H3/t20-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Inhibition of [3H]3-beta-(p-fluorophenyl)tropane-2beta-carboxylic acid methyl ester [3H]7a binding to Dopamine transporter of rat striatal membranes				J Med Chem 60: 7984-7999 (2017) Article DOI: 10.1021/acs.jmedchem.7b00462 BindingDB Entry DOI: 10.7270/Q2M32XX8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50241486 (CHEMBL4097953) Show SMILES NC1CCN(CC1)C(=O)CN(Cc1ccc(C#N)c(F)c1)c1ccc(cc1)C#N Show InChI InChI=1S/C22H22FN5O/c23-21-11-17(1-4-18(21)13-25)14-28(20-5-2-16(12-24)3-6-20)15-22(29)27-9-7-19(26)8-10-27/h1-6,11,19H,7-10,14-15,26H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Inhibition of N-terminal truncated human LSD1 (151 to 852 residues) expressed in Escherichia coli after 30 mins using histone H3(1-21)K4(Me1) biotin ...				J Med Chem 60: 7984-7999 (2017) Article DOI: 10.1021/acs.jmedchem.7b00462 BindingDB Entry DOI: 10.7270/Q2M32XX8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50242943 (CHEMBL4065043) Show SMILES N[C@@H]1CCCN(C1)C(=O)c1cc(OC[C@@H]2CCC(=O)N2)n(n1)-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C21H24N6O3/c22-11-14-3-6-17(7-4-14)27-20(30-13-16-5-8-19(28)24-16)10-18(25-27)21(29)26-9-1-2-15(23)12-26/h3-4,6-7,10,15-16H,1-2,5,8-9,12-13,23H2,(H,24,28)/t15-,16+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli using Histone H3(1 to 21)K4(Me1) biotin...				Bioorg Med Chem Lett 27: 3190-3195 (2017) Article DOI: 10.1016/j.bmcl.2017.05.018 BindingDB Entry DOI: 10.7270/Q2M047W8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50241506 (CHEMBL4101729) Show SMILES CNC1CCN(CC1)C(=O)CN(c1ccc(cc1)C#N)S(=O)(=O)c1ccc(C)cc1 Show InChI InChI=1S/C22H26N4O3S/c1-17-3-9-21(10-4-17)30(28,29)26(20-7-5-18(15-23)6-8-20)16-22(27)25-13-11-19(24-2)12-14-25/h3-10,19,24H,11-14,16H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Inhibition of [3H]3-beta-(p-fluorophenyl)tropane-2beta-carboxylic acid methyl ester [3H]7a binding to Dopamine transporter of rat striatal membranes				J Med Chem 60: 7984-7999 (2017) Article DOI: 10.1021/acs.jmedchem.7b00462 BindingDB Entry DOI: 10.7270/Q2M32XX8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50241537 (CHEMBL4064746) Show SMILES Cc1ccc(cc1)S(=O)(=O)N(CC(=O)N1CCC(N)CC1)c1ccc(cc1)C#N Show InChI InChI=1S/C21H24N4O3S/c1-16-2-8-20(9-3-16)29(27,28)25(19-6-4-17(14-22)5-7-19)15-21(26)24-12-10-18(23)11-13-24/h2-9,18H,10-13,15,23H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Inhibition of N-terminal truncated human LSD1 (151 to 852 residues) expressed in Escherichia coli after 30 mins using histone H3(1-21)K4(Me1) biotin ...				J Med Chem 60: 7984-7999 (2017) Article DOI: 10.1021/acs.jmedchem.7b00462 BindingDB Entry DOI: 10.7270/Q2M32XX8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50241517 (CHEMBL4072551) Show SMILES Cc1ccc(cc1)S(=O)(=O)N(CC(=O)N[C@H]1CN2CCC1CC2)c1ccc(cc1)C#N |r,wD:15.15,(17.25,-37.07,;15.92,-37.85,;15.92,-39.39,;14.6,-40.16,;13.27,-39.39,;13.25,-37.86,;14.58,-37.08,;11.93,-40.16,;12.69,-41.49,;11.16,-41.48,;10.6,-39.4,;10.59,-37.86,;9.25,-37.09,;7.92,-37.87,;9.25,-35.55,;10.58,-34.78,;11.92,-35.54,;13.25,-34.77,;13.25,-33.23,;11.91,-32.46,;10.57,-33.24,;12.1,-33.23,;11.7,-34.72,;9.26,-40.17,;7.93,-39.41,;6.6,-40.18,;6.6,-41.72,;7.93,-42.5,;9.27,-41.72,;5.27,-42.5,;3.93,-43.27,)| Show InChI InChI=1S/C23H26N4O3S/c1-17-2-8-21(9-3-17)31(29,30)27(20-6-4-18(14-24)5-7-20)16-23(28)25-22-15-26-12-10-19(22)11-13-26/h2-9,19,22H,10-13,15-16H2,1H3,(H,25,28)/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.19E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Inhibition of N-terminal truncated human LSD1 (151 to 852 residues) expressed in Escherichia coli after 30 mins using histone H3(1-21)K4(Me1) biotin ...				J Med Chem 60: 7984-7999 (2017) Article DOI: 10.1021/acs.jmedchem.7b00462 BindingDB Entry DOI: 10.7270/Q2M32XX8
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50241526 (CHEMBL4095018) Show SMILES COc1ccc(CN(CC(=O)N2CCC(CN)CC2)c2ccc(cc2)C#N)cc1F Show InChI InChI=1S/C23H27FN4O2/c1-30-22-7-4-19(12-21(22)24)15-28(20-5-2-17(13-25)3-6-20)16-23(29)27-10-8-18(14-26)9-11-27/h2-7,12,18H,8-11,14-16,26H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Inhibition of human hERG by patch clamp method				J Med Chem 60: 7984-7999 (2017) Article DOI: 10.1021/acs.jmedchem.7b00462 BindingDB Entry DOI: 10.7270/Q2M32XX8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50241505 (CHEMBL4073334) Show SMILES CN(C)C1CCN(CC1)C(=O)CN(c1ccc(cc1)C#N)S(=O)(=O)c1ccc(C)cc1 Show InChI InChI=1S/C23H28N4O3S/c1-18-4-10-22(11-5-18)31(29,30)27(21-8-6-19(16-24)7-9-21)17-23(28)26-14-12-20(13-15-26)25(2)3/h4-11,20H,12-15,17H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Inhibition of N-terminal truncated human LSD1 (151 to 852 residues) expressed in Escherichia coli after 30 mins using histone H3(1-21)K4(Me1) biotin ...				J Med Chem 60: 7984-7999 (2017) Article DOI: 10.1021/acs.jmedchem.7b00462 BindingDB Entry DOI: 10.7270/Q2M32XX8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50241516 (CHEMBL4083030) Show SMILES [H][C@]12CN(C(=O)CN(c3ccc(cc3)C#N)S(=O)(=O)c3ccc(C)cc3)[C@]([H])(CN1)C2 |r| Show InChI InChI=1S/C21H22N4O3S/c1-15-2-8-20(9-3-15)29(27,28)25(18-6-4-16(11-22)5-7-18)14-21(26)24-13-17-10-19(24)12-23-17/h2-9,17,19,23H,10,12-14H2,1H3/t17-,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Inhibition of N-terminal truncated human LSD1 (151 to 852 residues) expressed in Escherichia coli after 30 mins using histone H3(1-21)K4(Me1) biotin ...				J Med Chem 60: 7984-7999 (2017) Article DOI: 10.1021/acs.jmedchem.7b00462 BindingDB Entry DOI: 10.7270/Q2M32XX8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50241511 (CHEMBL4097636) Show SMILES Cc1ccc(cc1)S(=O)(=O)N(CC(=O)N1CCC[C@@H](N)C1)c1ccc(cc1)C#N |r| Show InChI InChI=1S/C21H24N4O3S/c1-16-4-10-20(11-5-16)29(27,28)25(19-8-6-17(13-22)7-9-19)15-21(26)24-12-2-3-18(23)14-24/h4-11,18H,2-3,12,14-15,23H2,1H3/t18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.39E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Inhibition of N-terminal truncated human LSD1 (151 to 852 residues) expressed in Escherichia coli after 30 mins using histone H3(1-21)K4(Me1) biotin ...				J Med Chem 60: 7984-7999 (2017) Article DOI: 10.1021/acs.jmedchem.7b00462 BindingDB Entry DOI: 10.7270/Q2M32XX8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50241538 (CHEMBL4101011) Show SMILES Cc1ccc(cc1)S(=O)(=O)N(CC(=O)N[C@@H]1CN2CCC1CC2)c1ccc(cc1)C#N |r,wU:15.15,(36.24,-5.68,;34.91,-6.46,;34.91,-8,;33.59,-8.77,;32.26,-8,;32.25,-6.47,;33.57,-5.69,;30.92,-8.77,;31.68,-10.1,;30.15,-10.09,;29.59,-8.01,;29.58,-6.47,;28.24,-5.7,;26.91,-6.48,;28.24,-4.16,;29.57,-3.39,;30.91,-4.15,;32.24,-3.38,;32.24,-1.84,;30.9,-1.07,;29.56,-1.85,;31.09,-1.84,;30.69,-3.33,;28.26,-8.78,;26.92,-8.02,;25.59,-8.79,;25.59,-10.34,;26.92,-11.11,;28.26,-10.33,;24.26,-11.11,;22.93,-11.88,)| Show InChI InChI=1S/C23H26N4O3S/c1-17-2-8-21(9-3-17)31(29,30)27(20-6-4-18(14-24)5-7-20)16-23(28)25-22-15-26-12-10-19(22)11-13-26/h2-9,19,22H,10-13,15-16H2,1H3,(H,25,28)/t22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.42E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Inhibition of N-terminal truncated human LSD1 (151 to 852 residues) expressed in Escherichia coli after 30 mins using histone H3(1-21)K4(Me1) biotin ...				J Med Chem 60: 7984-7999 (2017) Article DOI: 10.1021/acs.jmedchem.7b00462 BindingDB Entry DOI: 10.7270/Q2M32XX8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50241509 (CHEMBL4086227) Show SMILES Cc1ccc(cc1)S(=O)(=O)N(CC(=O)NC1CCNCC1)c1ccc(cc1)C#N Show InChI InChI=1S/C21H24N4O3S/c1-16-2-8-20(9-3-16)29(27,28)25(19-6-4-17(14-22)5-7-19)15-21(26)24-18-10-12-23-13-11-18/h2-9,18,23H,10-13,15H2,1H3,(H,24,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.56E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Inhibition of N-terminal truncated human LSD1 (151 to 852 residues) expressed in Escherichia coli after 30 mins using histone H3(1-21)K4(Me1) biotin ...				J Med Chem 60: 7984-7999 (2017) Article DOI: 10.1021/acs.jmedchem.7b00462 BindingDB Entry DOI: 10.7270/Q2M32XX8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50242947 (CHEMBL4083993) Show SMILES CC(Oc1cc(nn1-c1ccc(cc1)C#N)C(=O)N1CCC[C@@H](N)C1)C(N)=O |r| Show InChI InChI=1S/C19H22N6O3/c1-12(18(22)26)28-17-9-16(19(27)24-8-2-3-14(21)11-24)23-25(17)15-6-4-13(10-20)5-7-15/h4-7,9,12,14H,2-3,8,11,21H2,1H3,(H2,22,26)/t12?,14-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli using Histone H3(1 to 21)K4(Me1) biotin...				Bioorg Med Chem Lett 27: 3190-3195 (2017) Article DOI: 10.1016/j.bmcl.2017.05.018 BindingDB Entry DOI: 10.7270/Q2M047W8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50241536 (CHEMBL4078362) Show SMILES Cc1ccc(cc1)S(=O)(=O)N(CC(=O)N1CC[C@@H](N)C1)c1ccc(cc1)C#N |r| Show InChI InChI=1S/C20H22N4O3S/c1-15-2-8-19(9-3-15)28(26,27)24(18-6-4-16(12-21)5-7-18)14-20(25)23-11-10-17(22)13-23/h2-9,17H,10-11,13-14,22H2,1H3/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.64E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Inhibition of N-terminal truncated human LSD1 (151 to 852 residues) expressed in Escherichia coli after 30 mins using histone H3(1-21)K4(Me1) biotin ...				J Med Chem 60: 7984-7999 (2017) Article DOI: 10.1021/acs.jmedchem.7b00462 BindingDB Entry DOI: 10.7270/Q2M32XX8
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50241533 (CHEMBL4102775) Show SMILES COc1ccc(CN(CC(=O)N2CCC3(CNC3)CC2)c2ccc(cc2)C#N)cc1F Show InChI InChI=1S/C24H27FN4O2/c1-31-22-7-4-19(12-21(22)25)14-29(20-5-2-18(13-26)3-6-20)15-23(30)28-10-8-24(9-11-28)16-27-17-24/h2-7,12,27H,8-11,14-17H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Inhibition of human hERG by patch clamp method				J Med Chem 60: 7984-7999 (2017) Article DOI: 10.1021/acs.jmedchem.7b00462 BindingDB Entry DOI: 10.7270/Q2M32XX8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50241508 (CHEMBL4102632) Show SMILES Cc1ccc(cc1)S(=O)(=O)N(CC(=O)N1CC[C@H](N)C1)c1ccc(cc1)C#N |r| Show InChI InChI=1S/C20H22N4O3S/c1-15-2-8-19(9-3-15)28(26,27)24(18-6-4-16(12-21)5-7-18)14-20(25)23-11-10-17(22)13-23/h2-9,17H,10-11,13-14,22H2,1H3/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.27E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Inhibition of N-terminal truncated human LSD1 (151 to 852 residues) expressed in Escherichia coli after 30 mins using histone H3(1-21)K4(Me1) biotin ...				J Med Chem 60: 7984-7999 (2017) Article DOI: 10.1021/acs.jmedchem.7b00462 BindingDB Entry DOI: 10.7270/Q2M32XX8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50241510 (CHEMBL4079604) Show SMILES Cc1ccc(cc1)S(=O)(=O)N(CC(=O)N1CCC[C@H](N)C1)c1ccc(cc1)C#N |r| Show InChI InChI=1S/C21H24N4O3S/c1-16-4-10-20(11-5-16)29(27,28)25(19-8-6-17(13-22)7-9-19)15-21(26)24-12-2-3-18(23)14-24/h4-11,18H,2-3,12,14-15,23H2,1H3/t18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.43E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Inhibition of N-terminal truncated human LSD1 (151 to 852 residues) expressed in Escherichia coli after 30 mins using histone H3(1-21)K4(Me1) biotin ...				J Med Chem 60: 7984-7999 (2017) Article DOI: 10.1021/acs.jmedchem.7b00462 BindingDB Entry DOI: 10.7270/Q2M32XX8
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50241495 (CHEMBL4079933) Show SMILES COc1ccc(CN(CC(=O)N2CCC(N)CC2)c2ccc(cc2)C#N)cc1F Show InChI InChI=1S/C22H25FN4O2/c1-29-21-7-4-17(12-20(21)23)14-27(19-5-2-16(13-24)3-6-19)15-22(28)26-10-8-18(25)9-11-26/h2-7,12,18H,8-11,14-15,25H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Inhibition of human hERG by patch clamp method				J Med Chem 60: 7984-7999 (2017) Article DOI: 10.1021/acs.jmedchem.7b00462 BindingDB Entry DOI: 10.7270/Q2M32XX8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50241500 (CHEMBL4077134) Show SMILES Cn1cc2cc(ccc2n1)N(CC(=O)N1CCC[C@@H](N)C1)S(=O)(=O)c1ccc(cc1)C#N |r| Show InChI InChI=1S/C22H24N6O3S/c1-26-13-17-11-19(6-9-21(17)25-26)28(15-22(29)27-10-2-3-18(24)14-27)32(30,31)20-7-4-16(12-23)5-8-20/h4-9,11,13,18H,2-3,10,14-15,24H2,1H3/t18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Inhibition of N-terminal truncated human LSD1 (151 to 852 residues) expressed in Escherichia coli after 30 mins using histone H3(1-21)K4(Me1) biotin ...				J Med Chem 60: 7984-7999 (2017) Article DOI: 10.1021/acs.jmedchem.7b00462 BindingDB Entry DOI: 10.7270/Q2M32XX8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50241498 (CHEMBL4059468) Show SMILES COc1cc(ccc1-n1nc(C)cc1C)N(CC(=O)N1CCC(N)CC1)S(=O)(=O)c1ccc2N(CCc2c1)C(C)=O Show InChI InChI=1S/C29H36N6O5S/c1-19-15-20(2)35(31-19)27-7-5-24(17-28(27)40-4)34(18-29(37)32-12-10-23(30)11-13-32)41(38,39)25-6-8-26-22(16-25)9-14-33(26)21(3)36/h5-8,15-17,23H,9-14,18,30H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Inhibition of N-terminal truncated human LSD1 (151 to 852 residues) expressed in Escherichia coli after 30 mins using histone H3(1-21)K4(Me1) biotin ...				J Med Chem 60: 7984-7999 (2017) Article DOI: 10.1021/acs.jmedchem.7b00462 BindingDB Entry DOI: 10.7270/Q2M32XX8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50241522 (CHEMBL1607608) Show SMILES COc1cc(NS(=O)(=O)c2ccccc2)ccc1-n1nc(C)cc1C Show InChI InChI=1S/C18H19N3O3S/c1-13-11-14(2)21(19-13)17-10-9-15(12-18(17)24-3)20-25(22,23)16-7-5-4-6-8-16/h4-12,20H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Binding potency against Vasopressin V1 receptor in rat liver cells.				J Med Chem 60: 7984-7999 (2017) Article DOI: 10.1021/acs.jmedchem.7b00462 BindingDB Entry DOI: 10.7270/Q2M32XX8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50242958 (CHEMBL4070901) Show SMILES N[C@@H]1CCCN(C1)C(=O)c1cc(OCC(N)=O)n(n1)-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C18H20N6O3/c19-9-12-3-5-14(6-4-12)24-17(27-11-16(21)25)8-15(22-24)18(26)23-7-1-2-13(20)10-23/h3-6,8,13H,1-2,7,10-11,20H2,(H2,21,25)/t13-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli using Histone H3(1 to 21)K4(Me1) biotin...				Bioorg Med Chem Lett 27: 3190-3195 (2017) Article DOI: 10.1016/j.bmcl.2017.05.018 BindingDB Entry DOI: 10.7270/Q2M047W8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50241518 (CHEMBL4093280) Show SMILES Cc1ccc(cc1)S(=O)(=O)N(CC(=O)Nc1cccnc1)c1ccc(cc1)C#N Show InChI InChI=1S/C21H18N4O3S/c1-16-4-10-20(11-5-16)29(27,28)25(19-8-6-17(13-22)7-9-19)15-21(26)24-18-3-2-12-23-14-18/h2-12,14H,15H2,1H3,(H,24,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Inhibition of N-terminal truncated human LSD1 (151 to 852 residues) expressed in Escherichia coli after 30 mins using histone H3(1-21)K4(Me1) biotin ...				J Med Chem 60: 7984-7999 (2017) Article DOI: 10.1021/acs.jmedchem.7b00462 BindingDB Entry DOI: 10.7270/Q2M32XX8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50242885 (CHEMBL4101077) Show SMILES Cc1cc(COc2cc(nn2-c2ccc(cc2)C#N)C(=O)N2CC[C@@H](N)C2)on1 |r| Show InChI InChI=1S/C20H20N6O3/c1-13-8-17(29-24-13)12-28-19-9-18(20(27)25-7-6-15(22)11-25)23-26(19)16-4-2-14(10-21)3-5-16/h2-5,8-9,15H,6-7,11-12,22H2,1H3/t15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Reversible inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli by SPR analysis				Bioorg Med Chem Lett 27: 3190-3195 (2017) Article DOI: 10.1016/j.bmcl.2017.05.018 BindingDB Entry DOI: 10.7270/Q2M047W8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50242947 (CHEMBL4083993) Show SMILES CC(Oc1cc(nn1-c1ccc(cc1)C#N)C(=O)N1CCC[C@@H](N)C1)C(N)=O |r| Show InChI InChI=1S/C19H22N6O3/c1-12(18(22)26)28-17-9-16(19(27)24-8-2-3-14(21)11-24)23-25(17)15-6-4-13(10-20)5-7-15/h4-7,9,12,14H,2-3,8,11,21H2,1H3,(H2,22,26)/t12?,14-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Reversible inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli by SPR analysis				Bioorg Med Chem Lett 27: 3190-3195 (2017) Article DOI: 10.1016/j.bmcl.2017.05.018 BindingDB Entry DOI: 10.7270/Q2M047W8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301063 (4-{3-[((3R)-3- aminopiperidyl)carbonyl]-5-(2- pyri...) Show SMILES N[C@@H]1CCCN(C1)C(=O)c1cc(OCc2ccccn2)n(n1)-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C22H22N6O2/c23-13-16-6-8-19(9-7-16)28-21(30-15-18-5-1-2-10-25-18)12-20(26-28)22(29)27-11-3-4-17(24)14-27/h1-2,5-10,12,17H,3-4,11,14-15,24H2/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Reversible inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli by SPR analysis				Bioorg Med Chem Lett 27: 3190-3195 (2017) Article DOI: 10.1016/j.bmcl.2017.05.018 BindingDB Entry DOI: 10.7270/Q2M047W8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50242883 (CHEMBL4062785) Show SMILES Cc1cc(COc2cc(nn2-c2ccc(cc2)C#N)C(=O)N2CCC(N)CC2)on1 Show InChI InChI=1S/C21H22N6O3/c1-14-10-18(30-25-14)13-29-20-11-19(21(28)26-8-6-16(23)7-9-26)24-27(20)17-4-2-15(12-22)3-5-17/h2-5,10-11,16H,6-9,13,23H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	97	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Reversible inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli by SPR analysis				Bioorg Med Chem Lett 27: 3190-3195 (2017) Article DOI: 10.1016/j.bmcl.2017.05.018 BindingDB Entry DOI: 10.7270/Q2M047W8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50242884 (CHEMBL4090735) Show SMILES Cc1cc(COc2cc(nn2-c2ccc(cc2)C#N)C(=O)N2CC[C@@H](F)[C@@H](N)C2)on1 |r| Show InChI InChI=1S/C21H21FN6O3/c1-13-8-16(31-26-13)12-30-20-9-19(21(29)27-7-6-17(22)18(24)11-27)25-28(20)15-4-2-14(10-23)3-5-15/h2-5,8-9,17-18H,6-7,11-12,24H2,1H3/t17-,18+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Reversible inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli by SPR analysis				Bioorg Med Chem Lett 27: 3190-3195 (2017) Article DOI: 10.1016/j.bmcl.2017.05.018 BindingDB Entry DOI: 10.7270/Q2M047W8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50242886 (CHEMBL4104407) Show SMILES Cc1cc(COc2cc(nn2-c2ccc(cc2)C#N)C(=O)N2CCOC(CN)C2)on1 Show InChI InChI=1S/C21H22N6O4/c1-14-8-17(31-25-14)13-30-20-9-19(21(28)26-6-7-29-18(11-23)12-26)24-27(20)16-4-2-15(10-22)3-5-16/h2-5,8-9,18H,6-7,11-13,23H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Reversible inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli by SPR analysis				Bioorg Med Chem Lett 27: 3190-3195 (2017) Article DOI: 10.1016/j.bmcl.2017.05.018 BindingDB Entry DOI: 10.7270/Q2M047W8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50242890 (CHEMBL4077739) Show SMILES [H][C@@]12CN(C[C@]1([H])NCCC2)C(=O)c1cc(OCc2cc(C)no2)n(n1)-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C23H24N6O3/c1-15-9-19(32-27-15)14-31-22-10-20(26-29(22)18-6-4-16(11-24)5-7-18)23(30)28-12-17-3-2-8-25-21(17)13-28/h4-7,9-10,17,21,25H,2-3,8,12-14H2,1H3/t17-,21+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	99	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Reversible inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli by SPR analysis				Bioorg Med Chem Lett 27: 3190-3195 (2017) Article DOI: 10.1016/j.bmcl.2017.05.018 BindingDB Entry DOI: 10.7270/Q2M047W8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50242894 (CHEMBL4074323) Show SMILES CC(C)c1cc(COc2cc(nn2-c2ccc(cc2)C#N)C(=O)N2CCC[C@@H](N)C2)on1 |r| Show InChI InChI=1S/C23H26N6O3/c1-15(2)20-10-19(32-27-20)14-31-22-11-21(23(30)28-9-3-4-17(25)13-28)26-29(22)18-7-5-16(12-24)6-8-18/h5-8,10-11,15,17H,3-4,9,13-14,25H2,1-2H3/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Reversible inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli by SPR analysis				Bioorg Med Chem Lett 27: 3190-3195 (2017) Article DOI: 10.1016/j.bmcl.2017.05.018 BindingDB Entry DOI: 10.7270/Q2M047W8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50242896 (CHEMBL4093330) Show SMILES Cc1nnc(COc2cc(nn2-c2ccc(cc2)C#N)C(=O)N2CCC[C@@H](N)C2)o1 |r| Show InChI InChI=1S/C20H21N7O3/c1-13-23-24-18(30-13)12-29-19-9-17(20(28)26-8-2-3-15(22)11-26)25-27(19)16-6-4-14(10-21)5-7-16/h4-7,9,15H,2-3,8,11-12,22H2,1H3/t15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Reversible inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli by SPR analysis				Bioorg Med Chem Lett 27: 3190-3195 (2017) Article DOI: 10.1016/j.bmcl.2017.05.018 BindingDB Entry DOI: 10.7270/Q2M047W8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50242906 (CHEMBL4095757) Show SMILES Cn1ncnc1COc1cc(nn1-c1ccc(cc1)C#N)C(=O)N1CCC[C@@H](N)C1 |r| Show InChI InChI=1S/C20H22N8O2/c1-26-18(23-13-24-26)12-30-19-9-17(20(29)27-8-2-3-15(22)11-27)25-28(19)16-6-4-14(10-21)5-7-16/h4-7,9,13,15H,2-3,8,11-12,22H2,1H3/t15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Reversible inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli by SPR analysis				Bioorg Med Chem Lett 27: 3190-3195 (2017) Article DOI: 10.1016/j.bmcl.2017.05.018 BindingDB Entry DOI: 10.7270/Q2M047W8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50242942 (CHEMBL4092725) Show SMILES CC(O)COc1cc(nn1-c1ccc(cc1)C#N)C(=O)N1CCC[C@@H](N)C1 |r| Show InChI InChI=1S/C19H23N5O3/c1-13(25)12-27-18-9-17(19(26)23-8-2-3-15(21)11-23)22-24(18)16-6-4-14(10-20)5-7-16/h4-7,9,13,15,25H,2-3,8,11-12,21H2,1H3/t13?,15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Reversible inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli by SPR analysis				Bioorg Med Chem Lett 27: 3190-3195 (2017) Article DOI: 10.1016/j.bmcl.2017.05.018 BindingDB Entry DOI: 10.7270/Q2M047W8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50242943 (CHEMBL4065043) Show SMILES N[C@@H]1CCCN(C1)C(=O)c1cc(OC[C@@H]2CCC(=O)N2)n(n1)-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C21H24N6O3/c22-11-14-3-6-17(7-4-14)27-20(30-13-16-5-8-19(28)24-16)10-18(25-27)21(29)26-9-1-2-15(23)12-26/h3-4,6-7,10,15-16H,1-2,5,8-9,12-13,23H2,(H,24,28)/t15-,16+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Reversible inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli by SPR analysis				Bioorg Med Chem Lett 27: 3190-3195 (2017) Article DOI: 10.1016/j.bmcl.2017.05.018 BindingDB Entry DOI: 10.7270/Q2M047W8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50242945 (CHEMBL4073624) Show SMILES N[C@@H]1CCCN(C1)C(=O)c1cc(OCC(=O)N2CCOCC2)n(n1)-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C22H26N6O4/c23-13-16-3-5-18(6-4-16)28-21(32-15-20(29)26-8-10-31-11-9-26)12-19(25-28)22(30)27-7-1-2-17(24)14-27/h3-6,12,17H,1-2,7-11,14-15,24H2/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Reversible inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli by SPR analysis				Bioorg Med Chem Lett 27: 3190-3195 (2017) Article DOI: 10.1016/j.bmcl.2017.05.018 BindingDB Entry DOI: 10.7270/Q2M047W8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50242952 (CHEMBL4088035) Show SMILES CC(C)(O)CCOc1cc(nn1-c1ccc(cc1)C#N)C(=O)N1CCC[C@@H](N)C1 |r| Show InChI InChI=1S/C21H27N5O3/c1-21(2,28)9-11-29-19-12-18(20(27)25-10-3-4-16(23)14-25)24-26(19)17-7-5-15(13-22)6-8-17/h5-8,12,16,28H,3-4,9-11,14,23H2,1-2H3/t16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Reversible inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli by SPR analysis				Bioorg Med Chem Lett 27: 3190-3195 (2017) Article DOI: 10.1016/j.bmcl.2017.05.018 BindingDB Entry DOI: 10.7270/Q2M047W8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50242957 (CHEMBL4100451) Show SMILES N[C@@H]1CCCN(C1)C(=O)c1cc(OC[C@H]2CCC(=O)N2)n(n1)-c1ccc(cc1)C#N |r| Show InChI InChI=1S/C21H24N6O3/c22-11-14-3-6-17(7-4-14)27-20(30-13-16-5-8-19(28)24-16)10-18(25-27)21(29)26-9-1-2-15(23)12-26/h3-4,6-7,10,15-16H,1-2,5,8-9,12-13,23H2,(H,24,28)/t15-,16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Reversible inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli by SPR analysis				Bioorg Med Chem Lett 27: 3190-3195 (2017) Article DOI: 10.1016/j.bmcl.2017.05.018 BindingDB Entry DOI: 10.7270/Q2M047W8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50242948 (CHEMBL4082935) Show SMILES Cc1cc(COc2cc(nn2-c2ccc(cc2)C#N)C(=O)N2CCC(CN)CC2)on1 Show InChI InChI=1S/C22H24N6O3/c1-15-10-19(31-26-15)14-30-21-11-20(22(29)27-8-6-17(13-24)7-9-27)25-28(21)18-4-2-16(12-23)3-5-18/h2-5,10-11,17H,6-9,13-14,24H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Reversible inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli by SPR analysis				Bioorg Med Chem Lett 27: 3190-3195 (2017) Article DOI: 10.1016/j.bmcl.2017.05.018 BindingDB Entry DOI: 10.7270/Q2M047W8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50242951 (CHEMBL4096682) Show SMILES CCN(CC)C1CCN(C1)C(=O)c1cc(OCc2cc(C)no2)n(n1)-c1ccc(cc1)C#N Show InChI InChI=1S/C24H28N6O3/c1-4-28(5-2)20-10-11-29(15-20)24(31)22-13-23(32-16-21-12-17(3)27-33-21)30(26-22)19-8-6-18(14-25)7-9-19/h6-9,12-13,20H,4-5,10-11,15-16H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Reversible inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli by SPR analysis				Bioorg Med Chem Lett 27: 3190-3195 (2017) Article DOI: 10.1016/j.bmcl.2017.05.018 BindingDB Entry DOI: 10.7270/Q2M047W8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50241486 (CHEMBL4097953) Show SMILES NC1CCN(CC1)C(=O)CN(Cc1ccc(C#N)c(F)c1)c1ccc(cc1)C#N Show InChI InChI=1S/C22H22FN5O/c23-21-11-17(1-4-18(21)13-25)14-28(20-5-2-16(12-24)3-6-20)15-22(29)27-9-7-19(26)8-10-27/h1-6,11,19H,7-10,14-15,26H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Binding affinity to LSD1 (unknown origin) by SPR analysis				J Med Chem 60: 7984-7999 (2017) Article DOI: 10.1021/acs.jmedchem.7b00462 BindingDB Entry DOI: 10.7270/Q2M32XX8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50241492 (CHEMBL4063384) Show SMILES CC(=O)N1CCc2cc(ccc12)S(=O)(=O)N(CC(=O)N1CCC(N)CC1)c1ccc(cc1)C#N Show InChI InChI=1S/C24H27N5O4S/c1-17(30)28-13-8-19-14-22(6-7-23(19)28)34(32,33)29(21-4-2-18(15-25)3-5-21)16-24(31)27-11-9-20(26)10-12-27/h2-7,14,20H,8-13,16,26H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Binding affinity to LSD1 (unknown origin) by SPR analysis				J Med Chem 60: 7984-7999 (2017) Article DOI: 10.1021/acs.jmedchem.7b00462 BindingDB Entry DOI: 10.7270/Q2M32XX8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50241505 (CHEMBL4073334) Show SMILES CN(C)C1CCN(CC1)C(=O)CN(c1ccc(cc1)C#N)S(=O)(=O)c1ccc(C)cc1 Show InChI InChI=1S/C23H28N4O3S/c1-18-4-10-22(11-5-18)31(29,30)27(21-8-6-19(16-24)7-9-21)17-23(28)26-14-12-20(13-15-26)25(2)3/h4-11,20H,12-15,17H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Binding affinity to LSD1 (unknown origin) by SPR analysis				J Med Chem 60: 7984-7999 (2017) Article DOI: 10.1021/acs.jmedchem.7b00462 BindingDB Entry DOI: 10.7270/Q2M32XX8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50241506 (CHEMBL4101729) Show SMILES CNC1CCN(CC1)C(=O)CN(c1ccc(cc1)C#N)S(=O)(=O)c1ccc(C)cc1 Show InChI InChI=1S/C22H26N4O3S/c1-17-3-9-21(10-4-17)30(28,29)26(20-7-5-18(15-23)6-8-20)16-22(27)25-13-11-19(24-2)12-14-25/h3-10,19,24H,11-14,16H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Binding affinity to LSD1 (unknown origin) by SPR analysis				J Med Chem 60: 7984-7999 (2017) Article DOI: 10.1021/acs.jmedchem.7b00462 BindingDB Entry DOI: 10.7270/Q2M32XX8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50241507 (CHEMBL4083732) Show SMILES Cc1ccc(cc1)S(=O)(=O)N(CC(=O)N1CCC(C)(N)CC1)c1ccc(cc1)C#N Show InChI InChI=1S/C22H26N4O3S/c1-17-3-9-20(10-4-17)30(28,29)26(19-7-5-18(15-23)6-8-19)16-21(27)25-13-11-22(2,24)12-14-25/h3-10H,11-14,16,24H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Binding affinity to LSD1 (unknown origin) by SPR analysis				J Med Chem 60: 7984-7999 (2017) Article DOI: 10.1021/acs.jmedchem.7b00462 BindingDB Entry DOI: 10.7270/Q2M32XX8
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50241508 (CHEMBL4102632) Show SMILES Cc1ccc(cc1)S(=O)(=O)N(CC(=O)N1CC[C@H](N)C1)c1ccc(cc1)C#N |r| Show InChI InChI=1S/C20H22N4O3S/c1-15-2-8-19(9-3-15)28(26,27)24(18-6-4-16(12-21)5-7-18)14-20(25)23-11-10-17(22)13-23/h2-9,17H,10-11,13-14,22H2,1H3/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a
University of Manchester Curated by ChEMBL					Assay Description Binding affinity to LSD1 (unknown origin) by SPR analysis				J Med Chem 60: 7984-7999 (2017) Article DOI: 10.1021/acs.jmedchem.7b00462 BindingDB Entry DOI: 10.7270/Q2M32XX8
					More data for this Ligand-Target Pair

<<  First   |  Previous   |  Displayed 51 to 100 (of 144 total )  |  Next  |  Last  >>

Jump to: