BindingDB PrimarySearch

Found 11 hits of ki for UniProtKB: P0AD64
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Beta-lactamase SHV-1 (Klebsiella pneumoniae (Enterobacteria))	BDBM50053173 ((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	220	n/a	30	n/a	n/a	n/a	n/a	7.4	n/a
Case Western Reserve University					Assay Description Steady state kinetics were performed on an Agilent 8453 diode array spectrophotometer in 10 mM phosphate-buffered saline (pH 7.4). IC50, defined as t...				Biochemistry 54: 734-43 (2015) Article DOI: 10.1021/bi501197t BindingDB Entry DOI: 10.7270/Q2736PNW
Case Western Reserve University					More data for this Ligand-Target Pair				3D Structure (crystal)
Beta-lactamase SHV-1 (Klebsiella pneumoniae (Enterobacteria))	BDBM152696 (PSR-3-283A) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	560	n/a	320	n/a	n/a	n/a	n/a	7.4	n/a
Case Western Reserve University					Assay Description Steady state kinetics were performed on an Agilent 8453 diode array spectrophotometer in 10 mM phosphate-buffered saline (pH 7.4). IC50, defined as t...				Biochemistry 54: 734-43 (2015) Article DOI: 10.1021/bi501197t BindingDB Entry DOI: 10.7270/Q2736PNW
Case Western Reserve University					More data for this Ligand-Target Pair
Beta-lactamase SHV-1 (Klebsiella pneumoniae (Enterobacteria))	BDBM50021954 ((2S,5R)-3,3-Dimethyl-4,4,7-trioxo-4lambda6-thia-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	1.50E+3	n/a	3.40E+3	n/a	n/a	n/a	n/a	7.4	n/a
Case Western Reserve University					Assay Description Steady state kinetics were performed on an Agilent 8453 diode array spectrophotometer in 10 mM phosphate-buffered saline (pH 7.4). IC50, defined as t...				Biochemistry 54: 734-43 (2015) Article DOI: 10.1021/bi501197t BindingDB Entry DOI: 10.7270/Q2736PNW
Case Western Reserve University					More data for this Ligand-Target Pair				3D Structure (crystal)
Beta-lactamase SHV-1 (Klebsiella pneumoniae (Enterobacteria))	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.00E+3	n/a	100	n/a	n/a	n/a	n/a	7.4	n/a
Case Western Reserve University					Assay Description Steady state kinetics were performed on an Agilent 8453 diode array spectrophotometer in 10 mM phosphate-buffered saline (pH 7.4). IC50, defined as t...				Biochemistry 54: 734-43 (2015) Article DOI: 10.1021/bi501197t BindingDB Entry DOI: 10.7270/Q2736PNW
Case Western Reserve University					More data for this Ligand-Target Pair
Beta-lactamase SHV-1 (Klebsiella pneumoniae (Enterobacteria))	BDBM50370963 (CEFTAZIDIME BATSI) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	DrugBank PC cid PC sid PDB UniChem Similars	Article PubMed	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Veterans Affairs Medical Center Curated by ChEMBL					Assay Description Binding affinity at Beta-lactamase SHV1 expressed in Escherichia coli DH10B cells				Antimicrob Agents Chemother 51: 1577-9 (2007) Article DOI: 10.1128/AAC.01293-06 BindingDB Entry DOI: 10.7270/Q2WW7JG6
Veterans Affairs Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase SHV-1 (Klebsiella pneumoniae (Enterobacteria))	BDBM50486725 (CHEMBL2236666) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article	4.23E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Klebsiella pneumoniae beta-lactamase SHV-89				Citation and Details Article DOI: 10.1007/s00044-011-9736-8 BindingDB Entry DOI: 10.7270/Q2NC643K
TBA					More data for this Ligand-Target Pair
Beta-lactamase SHV-1 (Klebsiella pneumoniae (Enterobacteria))	BDBM50202234 ((Z)-(2-(2-aminothiazol-4-yl)-2-(methoxyimino)aceta...) Show SMILES CO\N=C(/C(=O)NCB(O)O)c1csc(N)n1 Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	Article PubMed	8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Veterans Affairs Medical Center Curated by ChEMBL					Assay Description Binding affinity at Beta-lactamase SHV1 expressed in Escherichia coli DH10B cells				Antimicrob Agents Chemother 51: 1577-9 (2007) Article DOI: 10.1128/AAC.01293-06 BindingDB Entry DOI: 10.7270/Q2WW7JG6
Veterans Affairs Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-lactamase SHV-1 (Klebsiella pneumoniae (Enterobacteria))	BDBM50486723 (PENEM-2) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article	6.79E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Klebsiella pneumoniae beta-lactamase SHV-89				Citation and Details Article DOI: 10.1007/s00044-011-9736-8 BindingDB Entry DOI: 10.7270/Q2NC643K
TBA					More data for this Ligand-Target Pair
Beta-lactamase SHV-1 (Klebsiella pneumoniae (Enterobacteria))	BDBM50486724 (PENEM-1) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article	1.10E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Klebsiella pneumoniae beta-lactamase SHV-89				Citation and Details Article DOI: 10.1007/s00044-011-9736-8 BindingDB Entry DOI: 10.7270/Q2NC643K
TBA					More data for this Ligand-Target Pair
Beta-lactamase SHV-1 (Klebsiella pneumoniae (Enterobacteria))	BDBM50021959 (CHEMBL777 \| MM 14151 \| US9120808, Clavulanic acid ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article	2.29E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Klebsiella pneumoniae beta-lactamase SHV-89				Citation and Details Article DOI: 10.1007/s00044-011-9736-8 BindingDB Entry DOI: 10.7270/Q2NC643K
TBA					More data for this Ligand-Target Pair
Beta-lactamase SHV-1 (Klebsiella pneumoniae (Enterobacteria))	BDBM50202233 (Acylglycineboronic acid, 5 \| CHEMBL227673 \| acetam...) Show SMILES CC(=O)NCB(O)O Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Veterans Affairs Medical Center Curated by ChEMBL					Assay Description Binding affinity at Beta-lactamase SHV1 expressed in Escherichia coli DH10B cells				Antimicrob Agents Chemother 51: 1577-9 (2007) Article DOI: 10.1128/AAC.01293-06 BindingDB Entry DOI: 10.7270/Q2WW7JG6
Veterans Affairs Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair