Compile Data Set for Download or QSAR

Found 67 hits Enz. Inhib. hit(s) with all data for entry = 3116   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28239 (2-(7-{5-[(4-fluorophenyl)methyl]-1,3,4-oxadiazol-2...) Show SMILES Oc1c(nc(N2CCCCS2(=O)=O)c2cccnc12)-c1nnc(Cc2ccc(F)cc2)o1 Show InChI InChI=1S/C21H18FN5O4S/c22-14-7-5-13(6-8-14)12-16-25-26-21(31-16)18-19(28)17-15(4-3-9-23-17)20(24-18)27-10-1-2-11-32(27,29)30/h3-9,28H,1-2,10-12H2	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28274 (1,3,4-oxadiazole substituted naphthyridine, 42 | 4...) Show SMILES OC(=O)c1ccc(cc1)-c1nc(-c2nnc(Cc3ccc(F)cc3)o2)c(O)c2ncccc12 Show InChI InChI=1S/C24H15FN4O4/c25-16-9-3-13(4-10-16)12-18-28-29-23(33-18)21-22(30)20-17(2-1-11-26-20)19(27-21)14-5-7-15(8-6-14)24(31)32/h1-11,30H,12H2,(H,31,32)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28269 (1,3,4-oxadiazole substituted naphthyridine, 37 | 3...) Show SMILES OC(=O)c1cccc(c1)-c1nc(-c2nnc(Cc3ccc(F)cc3)o2)c(O)c2ncccc12 Show InChI InChI=1S/C24H15FN4O4/c25-16-8-6-13(7-9-16)11-18-28-29-23(33-18)21-22(30)20-17(5-2-10-26-20)19(27-21)14-3-1-4-15(12-14)24(31)32/h1-10,12,30H,11H2,(H,31,32)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28285 (1,3,4-oxadiazole substituted naphthyridine, 53 | N...) Show SMILES CS(=O)(=O)Nc1ccc(cc1)-c1nc(-c2nnc(Cc3ccc(F)cc3)o2)c(O)c2ncccc12 Show InChI InChI=1S/C24H18FN5O4S/c1-35(32,33)30-17-10-6-15(7-11-17)20-18-3-2-12-26-21(18)23(31)22(27-20)24-29-28-19(34-24)13-14-4-8-16(25)9-5-14/h2-12,30-31H,13H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28292 (1,3,4-oxadiazole substituted naphthyridine, 60 | 7...) Show SMILES Oc1c(nc(-n2cccn2)c2cccnc12)-c1nnc(Cc2ccc(F)cc2)o1 Show InChI InChI=1S/C20H13FN6O2/c21-13-6-4-12(5-7-13)11-15-25-26-20(29-15)17-18(28)16-14(3-1-8-22-16)19(24-17)27-10-2-9-23-27/h1-10,28H,11H2	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28281 (1,3,4-oxadiazole substituted naphthyridine, 49 | 2...) Show SMILES CNS(=O)(=O)c1ccccc1-c1nc(-c2nnc(Cc3ccc(F)cc3)o2)c(O)c2ncccc12 Show InChI InChI=1S/C24H18FN5O4S/c1-26-35(32,33)18-7-3-2-5-16(18)20-17-6-4-12-27-21(17)23(31)22(28-20)24-30-29-19(34-24)13-14-8-10-15(25)11-9-14/h2-12,26,31H,13H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28279 (1,3,4-oxadiazole substituted naphthyridine, 47 | 2...) Show SMILES CN(C)S(=O)(=O)c1ccccc1-c1nc(-c2nnc(Cc3ccc(F)cc3)o2)c(O)c2ncccc12 Show InChI InChI=1S/C25H20FN5O4S/c1-31(2)36(33,34)19-8-4-3-6-17(19)21-18-7-5-13-27-22(18)24(32)23(28-21)25-30-29-20(35-25)14-15-9-11-16(26)12-10-15/h3-13,32H,14H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28278 (1,3,4-oxadiazole substituted naphthyridine, 46 | 4...) Show SMILES CC(C)NC(=O)c1ccc(cc1)-c1nc(-c2nnc(Cc3ccc(F)cc3)o2)c(O)c2ncccc12 Show InChI InChI=1S/C27H22FN5O3/c1-15(2)30-26(35)18-9-7-17(8-10-18)22-20-4-3-13-29-23(20)25(34)24(31-22)27-33-32-21(36-27)14-16-5-11-19(28)12-6-16/h3-13,15,34H,14H2,1-2H3,(H,30,35)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28283 (1,3,4-oxadiazole substituted naphthyridine, 51 | 4...) Show SMILES CC(C)NS(=O)(=O)c1ccc(cc1)-c1nc(-c2nnc(Cc3ccc(F)cc3)o2)c(O)c2ncccc12 Show InChI InChI=1S/C26H22FN5O4S/c1-15(2)32-37(34,35)19-11-7-17(8-12-19)22-20-4-3-13-28-23(20)25(33)24(29-22)26-31-30-21(36-26)14-16-5-9-18(27)10-6-16/h3-13,15,32-33H,14H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28276 (1,3,4-oxadiazole substituted naphthyridine, 44 | 4...) Show SMILES CNC(=O)c1ccc(cc1)-c1nc(-c2nnc(Cc3ccc(F)cc3)o2)c(O)c2ncccc12 Show InChI InChI=1S/C25H18FN5O3/c1-27-24(33)16-8-6-15(7-9-16)20-18-3-2-12-28-21(18)23(32)22(29-20)25-31-30-19(34-25)13-14-4-10-17(26)11-5-14/h2-12,32H,13H2,1H3,(H,27,33)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28284 (1,3,4-oxadiazole substituted naphthyridine, 52 | N...) Show SMILES CC(=O)Nc1ccc(cc1)-c1nc(-c2nnc(Cc3ccc(F)cc3)o2)c(O)c2ncccc12 Show InChI InChI=1S/C25H18FN5O3/c1-14(32)28-18-10-6-16(7-11-18)21-19-3-2-12-27-22(19)24(33)23(29-21)25-31-30-20(34-25)13-15-4-8-17(26)9-5-15/h2-12,33H,13H2,1H3,(H,28,32)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28258 (1,3,4-oxadiazole substituted naphthyridine, 25 | 2...) Show SMILES CN1CCN(c2nc(-c3nnc(Cc4ccc(F)cc4)o3)c(O)c3ncccc23)S1(=O)=O Show InChI InChI=1S/C20H17FN6O4S/c1-26-9-10-27(32(26,29)30)19-14-3-2-8-22-16(14)18(28)17(23-19)20-25-24-15(31-20)11-12-4-6-13(21)7-5-12/h2-8,28H,9-11H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	7.2	37
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28257 (1,3,4-oxadiazole substituted naphthyridine, 24 | 2...) Show SMILES CN1CCCN(c2nc(-c3nnc(Cc4ccc(F)cc4)o3)c(O)c3ncccc23)S1(=O)=O Show InChI InChI=1S/C21H19FN6O4S/c1-27-10-3-11-28(33(27,30)31)20-15-4-2-9-23-17(15)19(29)18(24-20)21-26-25-16(32-21)12-13-5-7-14(22)8-6-13/h2,4-9,29H,3,10-12H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	7.2	37
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28287 (1,3,4-oxadiazole substituted naphthyridine, 55 | 7...) Show SMILES CS(=O)(=O)c1cccc(c1)-c1nc(-c2nnc(Cc3ccc(F)cc3)o2)c(O)c2ncccc12 Show InChI InChI=1S/C24H17FN4O4S/c1-34(31,32)17-5-2-4-15(13-17)20-18-6-3-11-26-21(18)23(30)22(27-20)24-29-28-19(33-24)12-14-7-9-16(25)10-8-14/h2-11,13,30H,12H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28275 (1,3,4-oxadiazole substituted naphthyridine, 43 | 4...) Show SMILES NC(=O)c1ccc(cc1)-c1nc(-c2nnc(Cc3ccc(F)cc3)o2)c(O)c2ncccc12 Show InChI InChI=1S/C24H16FN5O3/c25-16-9-3-13(4-10-16)12-18-29-30-24(33-18)21-22(31)20-17(2-1-11-27-20)19(28-21)14-5-7-15(8-6-14)23(26)32/h1-11,31H,12H2,(H2,26,32)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28260 (1,3,4-oxadiazole substituted naphthyridine, 27 | 4...) Show SMILES Oc1c(nc(N2CCNC(=O)C2)c2cccnc12)-c1nnc(Cc2ccc(F)cc2)o1 Show InChI InChI=1S/C21H17FN6O3/c22-13-5-3-12(4-6-13)10-16-26-27-21(31-16)18-19(30)17-14(2-1-7-24-17)20(25-18)28-9-8-23-15(29)11-28/h1-7,30H,8-11H2,(H,23,29)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	7.2	37
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28254 (1,3,4-oxadiazole substituted naphthyridine, 21 | 2...) Show SMILES Oc1c(nc(N2CCCS2(=O)=O)c2cccnc12)-c1nnc(Cc2ccc(F)cc2)o1 Show InChI InChI=1S/C20H16FN5O4S/c21-13-6-4-12(5-7-13)11-15-24-25-20(30-15)17-18(27)16-14(3-1-8-22-16)19(23-17)26-9-2-10-31(26,28)29/h1,3-8,27H,2,9-11H2	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	7.2	37
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28267 (1,3,4-oxadiazole substituted naphthyridine, 35 | 7...) Show SMILES Oc1c(nc(-c2ccncc2)c2cccnc12)-c1nnc(Cc2ccc(F)cc2)o1 Show InChI InChI=1S/C22H14FN5O2/c23-15-5-3-13(4-6-15)12-17-27-28-22(30-17)20-21(29)19-16(2-1-9-25-19)18(26-20)14-7-10-24-11-8-14/h1-11,29H,12H2	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28273 (1,3,4-oxadiazole substituted naphthyridine, 41 | N...) Show SMILES CS(=O)(=O)Nc1cccc(c1)-c1nc(-c2nnc(Cc3ccc(F)cc3)o2)c(O)c2ncccc12 Show InChI InChI=1S/C24H18FN5O4S/c1-35(32,33)30-17-5-2-4-15(13-17)20-18-6-3-11-26-21(18)23(31)22(27-20)24-29-28-19(34-24)12-14-7-9-16(25)10-8-14/h2-11,13,30-31H,12H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28288 (1,3,4-oxadiazole substituted naphthyridine, 56 | 7...) Show SMILES CS(=O)(=O)c1ccc(cc1)-c1nc(-c2nnc(Cc3ccc(F)cc3)o2)c(O)c2ncccc12 Show InChI InChI=1S/C24H17FN4O4S/c1-34(31,32)17-10-6-15(7-11-17)20-18-3-2-12-26-21(18)23(30)22(27-20)24-29-28-19(33-24)13-14-4-8-16(25)9-5-14/h2-12,30H,13H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28270 (1,3,4-oxadiazole substituted naphthyridine, 38 | 3...) Show SMILES CC(C)NC(=O)c1cccc(c1)-c1nc(-c2nnc(Cc3ccc(F)cc3)o2)c(O)c2ncccc12 Show InChI InChI=1S/C27H22FN5O3/c1-15(2)30-26(35)18-6-3-5-17(14-18)22-20-7-4-12-29-23(20)25(34)24(31-22)27-33-32-21(36-27)13-16-8-10-19(28)11-9-16/h3-12,14-15,34H,13H2,1-2H3,(H,30,35)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28253 (1,3,4-oxadiazole substituted naphthyridine, 20 | 1...) Show SMILES Oc1c(nc(N2CCCNC2=O)c2cccnc12)-c1nnc(Cc2ccc(F)cc2)o1 Show InChI InChI=1S/C21H17FN6O3/c22-13-6-4-12(5-7-13)11-15-26-27-20(31-15)17-18(29)16-14(3-1-8-23-16)19(25-17)28-10-2-9-24-21(28)30/h1,3-8,29H,2,9-11H2,(H,24,30)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	7.2	37
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28286 (1,3,4-oxadiazole substituted naphthyridine, 54 | 7...) Show SMILES CS(=O)(=O)c1ccccc1-c1nc(-c2nnc(Cc3ccc(F)cc3)o2)c(O)c2ncccc12 Show InChI InChI=1S/C24H17FN4O4S/c1-34(31,32)18-7-3-2-5-16(18)20-17-6-4-12-26-21(17)23(30)22(27-20)24-29-28-19(33-24)13-14-8-10-15(25)11-9-14/h2-12,30H,13H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28266 (1,3,4-oxadiazole substituted naphthyridine, 34 | 7...) Show SMILES Oc1c(nc(-c2cccnc2)c2cccnc12)-c1nnc(Cc2ccc(F)cc2)o1 Show InChI InChI=1S/C22H14FN5O2/c23-15-7-5-13(6-8-15)11-17-27-28-22(30-17)20-21(29)19-16(4-2-10-25-19)18(26-20)14-3-1-9-24-12-14/h1-10,12,29H,11H2	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28282 (1,3,4-oxadiazole substituted naphthyridine, 50 | 2...) Show SMILES CC(C)NS(=O)(=O)c1ccccc1-c1nc(-c2nnc(Cc3ccc(F)cc3)o2)c(O)c2ncccc12 Show InChI InChI=1S/C26H22FN5O4S/c1-15(2)32-37(34,35)20-8-4-3-6-18(20)22-19-7-5-13-28-23(19)25(33)24(29-22)26-31-30-21(36-26)14-16-9-11-17(27)12-10-16/h3-13,15,32-33H,14H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28263 (1,3,4-oxadiazole substituted naphthyridine, 31 | 2...) Show SMILES CN(C)C(=O)CN1CCN(CC1)c1nc(-c2nnc(Cc3ccc(F)cc3)o2)c(O)c2ncccc12 Show InChI InChI=1S/C25H26FN7O3/c1-31(2)20(34)15-32-10-12-33(13-11-32)24-18-4-3-9-27-21(18)23(35)22(28-24)25-30-29-19(36-25)14-16-5-7-17(26)8-6-16/h3-9,35H,10-15H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28250 (1,3,4-oxadiazole substituted naphthyridine, 17 | 1...) Show SMILES Oc1c(nc(N2CCNC2=O)c2cccnc12)-c1nnc(Cc2ccc(F)cc2)o1 Show InChI InChI=1S/C20H15FN6O3/c21-12-5-3-11(4-6-12)10-14-25-26-19(30-14)16-17(28)15-13(2-1-7-22-15)18(24-16)27-9-8-23-20(27)29/h1-7,28H,8-10H2,(H,23,29)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	7.2	37
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28291 (1,3,4-oxadiazole substituted naphthyridine, 59 | 7...) Show SMILES Oc1c(nc(-c2ccc[nH]2)c2cccnc12)-c1nnc(Cc2ccc(F)cc2)o1 Show InChI InChI=1S/C21H14FN5O2/c22-13-7-5-12(6-8-13)11-16-26-27-21(29-16)19-20(28)18-14(3-1-10-24-18)17(25-19)15-4-2-9-23-15/h1-10,23,28H,11H2	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28252 (1,3,4-oxadiazole substituted naphthyridine, 19 | 3...) Show SMILES Oc1c(nc(N2CCOC2=O)c2cccnc12)-c1nnc(Cc2ccc(F)cc2)o1 Show InChI InChI=1S/C20H14FN5O4/c21-12-5-3-11(4-6-12)10-14-24-25-19(30-14)16-17(27)15-13(2-1-7-22-15)18(23-16)26-8-9-29-20(26)28/h1-7,27H,8-10H2	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	7.2	37
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28251 (1,3,4-oxadiazole substituted naphthyridine, 18 | 1...) Show SMILES OCCN1CCN(C1=O)c1nc(-c2nnc(Cc3ccc(F)cc3)o2)c(O)c2ncccc12 Show InChI InChI=1S/C22H19FN6O4/c23-14-5-3-13(4-6-14)12-16-26-27-21(33-16)18-19(31)17-15(2-1-7-24-17)20(25-18)29-9-8-28(10-11-30)22(29)32/h1-7,30-31H,8-12H2	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	7.2	37
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28271 (1,3,4-oxadiazole substituted naphthyridine, 39 | 5...) Show SMILES Nc1cccc(c1)-c1nc(-c2nnc(Cc3ccc(F)cc3)o2)c(O)c2ncccc12 Show InChI InChI=1S/C23H16FN5O2/c24-15-8-6-13(7-9-15)11-18-28-29-23(31-18)21-22(30)20-17(5-2-10-26-20)19(27-21)14-3-1-4-16(25)12-14/h1-10,12,30H,11,25H2	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28256 (1,3,4-oxadiazole substituted naphthyridine, 23 | 5...) Show SMILES CN(C)S(=O)(=O)Nc1nc(-c2nnc(Cc3ccc(F)cc3)o2)c(O)c2ncccc12 Show InChI InChI=1S/C19H17FN6O4S/c1-26(2)31(28,29)25-18-13-4-3-9-21-15(13)17(27)16(22-18)19-24-23-14(30-19)10-11-5-7-12(20)8-6-11/h3-9,27H,10H2,1-2H3,(H,22,25)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	7.2	37
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28249 (1,3,4-oxadiazole substituted naphthyridine, 16 | 1...) Show SMILES CN1CCN(C1=O)c1nc(-c2nnc(Cc3ccc(F)cc3)o2)c(O)c2ncccc12 Show InChI InChI=1S/C21H17FN6O3/c1-27-9-10-28(21(27)30)19-14-3-2-8-23-16(14)18(29)17(24-19)20-26-25-15(31-20)11-12-4-6-13(22)7-5-12/h2-8,29H,9-11H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	7.2	37
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28289 (1,3,4-oxadiazole substituted naphthyridine, 57 | 4...) Show SMILES Oc1c(nc(-c2ccc(cc2)C#N)c2cccnc12)-c1nnc(Cc2ccc(F)cc2)o1 Show InChI InChI=1S/C24H14FN5O2/c25-17-9-5-14(6-10-17)12-19-29-30-24(32-19)22-23(31)21-18(2-1-11-27-21)20(28-22)16-7-3-15(13-26)4-8-16/h1-11,31H,12H2	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28277 (1,3,4-oxadiazole substituted naphthyridine, 45 | 4...) Show SMILES CN(C)C(=O)c1ccc(cc1)-c1nc(-c2nnc(Cc3ccc(F)cc3)o2)c(O)c2ncccc12 Show InChI InChI=1S/C26H20FN5O3/c1-32(2)26(34)17-9-7-16(8-10-17)21-19-4-3-13-28-22(19)24(33)23(29-21)25-31-30-20(35-25)14-15-5-11-18(27)12-6-15/h3-13,33H,14H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28280 (1,3,4-oxadiazole substituted naphthyridine, 48 | 4...) Show SMILES CN(C)S(=O)(=O)c1ccc(cc1)-c1nc(-c2nnc(Cc3ccc(F)cc3)o2)c(O)c2ncccc12 Show InChI InChI=1S/C25H20FN5O4S/c1-31(2)36(33,34)18-11-7-16(8-12-18)21-19-4-3-13-27-22(19)24(32)23(28-21)25-30-29-20(35-25)14-15-5-9-17(26)10-6-15/h3-13,32H,14H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28240 (1,3,4-oxadiazole substituted naphthyridine, 7 | 1-...) Show SMILES Oc1c(nc(N2CCCC2=O)c2cccnc12)-c1nnc(Cc2ccc(F)cc2)o1 Show InChI InChI=1S/C21H16FN5O3/c22-13-7-5-12(6-8-13)11-15-25-26-21(30-15)18-19(29)17-14(3-1-9-23-17)20(24-18)27-10-2-4-16(27)28/h1,3,5-9,29H,2,4,10-11H2	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	7.2	37
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28255 (1,3,4-oxadiazole substituted naphthyridine, 22 | N...) Show SMILES CS(=O)(=O)Nc1nc(-c2nnc(Cc3ccc(F)cc3)o2)c(O)c2ncccc12 Show InChI InChI=1S/C18H14FN5O4S/c1-29(26,27)24-17-12-3-2-8-20-14(12)16(25)15(21-17)18-23-22-13(28-18)9-10-4-6-11(19)7-5-10/h2-8,25H,9H2,1H3,(H,21,24)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	7.2	37
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28262 (1,3,4-oxadiazole substituted naphthyridine, 30 | 7...) Show SMILES CS(=O)(=O)N1CCN(CC1)c1nc(-c2nnc(Cc3ccc(F)cc3)o2)c(O)c2ncccc12 Show InChI InChI=1S/C22H21FN6O4S/c1-34(31,32)29-11-9-28(10-12-29)21-16-3-2-8-24-18(16)20(30)19(25-21)22-27-26-17(33-22)13-14-4-6-15(23)7-5-14/h2-8,30H,9-13H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28268 (1,3,4-oxadiazole substituted naphthyridine, 36 | 7...) Show SMILES Oc1c(nc(-c2cnccn2)c2cccnc12)-c1nnc(Cc2ccc(F)cc2)o1 Show InChI InChI=1S/C21H13FN6O2/c22-13-5-3-12(4-6-13)10-16-27-28-21(30-16)19-20(29)18-14(2-1-7-25-18)17(26-19)15-11-23-8-9-24-15/h1-9,11,29H,10H2	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28293 (1,3,4-oxadiazole substituted naphthyridine, 61 | 7...) Show SMILES Cc1ccn(n1)-c1nc(-c2nnc(Cc3ccc(F)cc3)o2)c(O)c2ncccc12 Show InChI InChI=1S/C21H15FN6O2/c1-12-8-10-28(27-12)20-15-3-2-9-23-17(15)19(29)18(24-20)21-26-25-16(30-21)11-13-4-6-14(22)7-5-13/h2-10,29H,11H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28290 (1,3,4-oxadiazole substituted naphthyridine, 58 | 7...) Show SMILES Oc1c(nc(-c2ccoc2)c2cccnc12)-c1nnc(Cc2ccc(F)cc2)o1 Show InChI InChI=1S/C21H13FN4O3/c22-14-5-3-12(4-6-14)10-16-25-26-21(29-16)19-20(27)18-15(2-1-8-23-18)17(24-19)13-7-9-28-11-13/h1-9,11,27H,10H2	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28248 (1,3,4-oxadiazole substituted naphthyridine, 15 | 4...) Show SMILES CN(C)C(=O)N1CCN(C(=O)C1)c1nc(-c2nnc(Cc3ccc(F)cc3)o2)c(O)c2ncccc12 Show InChI InChI=1S/C24H22FN7O4/c1-30(2)24(35)31-10-11-32(18(33)13-31)22-16-4-3-9-26-19(16)21(34)20(27-22)23-29-28-17(36-23)12-14-5-7-15(25)8-6-14/h3-9,34H,10-13H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	7.2	37
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28242 (1,3,4-oxadiazole substituted naphthyridine, 9 | 1-...) Show SMILES Oc1c(nc(N2CCCCCC2=O)c2cccnc12)-c1nnc(Cc2ccc(F)cc2)o1 Show InChI InChI=1S/C23H20FN5O3/c24-15-9-7-14(8-10-15)13-17-27-28-23(32-17)20-21(31)19-16(5-4-11-25-19)22(26-20)29-12-3-1-2-6-18(29)30/h4-5,7-11,31H,1-3,6,12-13H2	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	7.2	37
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28304 (1,3,4-oxadiazole substituted naphthyridine, 77 | 7...) Show SMILES OC1CCN(CC1)C(=O)c1nc(-c2nnc(Cc3ccc(F)cc3)o2)c(O)c2ncccc12 Show InChI InChI=1S/C23H20FN5O4/c24-14-5-3-13(4-6-14)12-17-27-28-22(33-17)20-21(31)18-16(2-1-9-25-18)19(26-20)23(32)29-10-7-15(30)8-11-29/h1-6,9,15,30-31H,7-8,10-12H2	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28244 (1,3,4-oxadiazole substituted naphthyridine, 11 | N...) Show SMILES CN(C(C)=O)c1nc(-c2nnc(Cc3ccc(F)cc3)o2)c(O)c2ncccc12 Show InChI InChI=1S/C20H16FN5O3/c1-11(27)26(2)19-14-4-3-9-22-16(14)18(28)17(23-19)20-25-24-15(29-20)10-12-5-7-13(21)8-6-12/h3-9,28H,10H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	7.2	37
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28264 (1,3,4-oxadiazole substituted naphthyridine, 32 | 7...) Show SMILES Oc1c(nc(-c2ccccc2)c2cccnc12)-c1nnc(Cc2ccc(F)cc2)o1 Show InChI InChI=1S/C23H15FN4O2/c24-16-10-8-14(9-11-16)13-18-27-28-23(30-18)21-22(29)20-17(7-4-12-25-20)19(26-21)15-5-2-1-3-6-15/h1-12,29H,13H2	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28265 (1,3,4-oxadiazole substituted naphthyridine, 33 | 7...) Show SMILES Oc1c(nc(-c2ccccn2)c2cccnc12)-c1nnc(Cc2ccc(F)cc2)o1 Show InChI InChI=1S/C22H14FN5O2/c23-14-8-6-13(7-9-14)12-17-27-28-22(30-17)20-21(29)19-15(4-3-11-25-19)18(26-20)16-5-1-2-10-24-16/h1-11,29H,12H2	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28245 (1,3,4-oxadiazole substituted naphthyridine, 12 | e...) Show SMILES CCOC(=O)C(=O)Nc1nc(-c2nnc(Cc3ccc(F)cc3)o2)c(O)c2ncccc12 Show InChI InChI=1S/C21H16FN5O5/c1-2-31-21(30)19(29)25-18-13-4-3-9-23-15(13)17(28)16(24-18)20-27-26-14(32-20)10-11-5-7-12(22)8-6-11/h3-9,28H,2,10H2,1H3,(H,24,25,29)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	7.2	37
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair
Gag-Pol polyprotein [1148-1435] (Human immunodeficiency virus type 1)	BDBM28247 (1,3,4-oxadiazole substituted naphthyridine, 14 | 1...) Show SMILES Oc1c(nc(N2CCNCC2=O)c2cccnc12)-c1nnc(Cc2ccc(F)cc2)o1 Show InChI InChI=1S/C21H17FN6O3/c22-13-5-3-12(4-6-13)10-15-26-27-21(31-15)18-19(30)17-14(2-1-7-24-17)20(25-18)28-9-8-23-11-16(28)29/h1-7,23,30H,8-11H2	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	7.2	37
GSK					Assay Description Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...				Bioorg Med Chem Lett 19: 1807-10 (2009) Article DOI: 10.1016/j.bmcl.2009.01.089 BindingDB Entry DOI: 10.7270/Q2TH8K1R
					More data for this Ligand-Target Pair

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