Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human)) | BDBM28759 ((2S)-3-phenyl-2-(4-phenylphenoxy)propanoic acid | ...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Similars | MMDB PDB Article PubMed | n/a | n/a | n/a | n/a | 480 | n/a | n/a | n/a | n/a |
Consiglio Nazionale delle Ricerche | Assay Description The HepG2 cells were co-transfected with DNA construct containing PPAR-Gal4 chimeric receptor and Gal4-luciferase reporter. The luciferase activity w... | J Med Chem 51: 7768-76 (2008) Article DOI: 10.1021/jm800733h BindingDB Entry DOI: 10.7270/Q2CC0Z0D | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human)) | BDBM28760 ((2R)-3-phenyl-2-(4-phenylphenoxy)propanoic acid | ...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MMDB PC cid PC sid UniChem Similars | MMDB Article PubMed | n/a | n/a | n/a | n/a | 5.93E+3 | n/a | n/a | n/a | n/a |
Consiglio Nazionale delle Ricerche | Assay Description The HepG2 cells were co-transfected with DNA construct containing PPAR-Gal4 chimeric receptor and Gal4-luciferase reporter. The luciferase activity w... | J Med Chem 51: 7768-76 (2008) Article DOI: 10.1021/jm800733h BindingDB Entry DOI: 10.7270/Q2CC0Z0D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human)) | BDBM28681 (5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | n/a | 40 | n/a | n/a | n/a | n/a |
Consiglio Nazionale delle Ricerche | Assay Description The HepG2 cells were co-transfected with DNA construct containing PPAR-Gal4 chimeric receptor and Gal4-luciferase reporter. The luciferase activity w... | J Med Chem 51: 7768-76 (2008) Article DOI: 10.1021/jm800733h BindingDB Entry DOI: 10.7270/Q2CC0Z0D | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human)) | BDBM28759 ((2S)-3-phenyl-2-(4-phenylphenoxy)propanoic acid | ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 220 | n/a | n/a | n/a | n/a |
Consiglio Nazionale delle Ricerche | Assay Description The HepG2 cells were co-transfected with DNA construct containing PPAR-Gal4 chimeric receptor and Gal4-luciferase reporter. The luciferase activity w... | J Med Chem 51: 7768-76 (2008) Article DOI: 10.1021/jm800733h BindingDB Entry DOI: 10.7270/Q2CC0Z0D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor alpha (Mus musculus) | BDBM28760 ((2R)-3-phenyl-2-(4-phenylphenoxy)propanoic acid | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MMDB PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Consiglio Nazionale delle Ricerche | Assay Description The HepG2 cells were co-transfected with DNA construct containing PPAR-Gal4 chimeric receptor and Gal4-luciferase reporter. The luciferase activity w... | J Med Chem 51: 7768-76 (2008) Article DOI: 10.1021/jm800733h BindingDB Entry DOI: 10.7270/Q2CC0Z0D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor alpha (Mus musculus) | BDBM28759 ((2S)-3-phenyl-2-(4-phenylphenoxy)propanoic acid | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 260 | n/a | n/a | n/a | n/a |
Consiglio Nazionale delle Ricerche | Assay Description The HepG2 cells were co-transfected with DNA construct containing PPAR-Gal4 chimeric receptor and Gal4-luciferase reporter. The luciferase activity w... | J Med Chem 51: 7768-76 (2008) Article DOI: 10.1021/jm800733h BindingDB Entry DOI: 10.7270/Q2CC0Z0D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor alpha (Mus musculus) | BDBM24566 (2-({4-chloro-6-[(2,3-dimethylphenyl)amino]pyrimidi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | n/a | 40 | n/a | n/a | n/a | n/a |
Consiglio Nazionale delle Ricerche | Assay Description The HepG2 cells were co-transfected with DNA construct containing PPAR-Gal4 chimeric receptor and Gal4-luciferase reporter. The luciferase activity w... | J Med Chem 51: 7768-76 (2008) Article DOI: 10.1021/jm800733h BindingDB Entry DOI: 10.7270/Q2CC0Z0D | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human)) | BDBM28760 ((2R)-3-phenyl-2-(4-phenylphenoxy)propanoic acid | ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MMDB PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Consiglio Nazionale delle Ricerche | Assay Description The HepG2 cells were co-transfected with DNA construct containing PPAR-Gal4 chimeric receptor and Gal4-luciferase reporter. The luciferase activity w... | J Med Chem 51: 7768-76 (2008) Article DOI: 10.1021/jm800733h BindingDB Entry DOI: 10.7270/Q2CC0Z0D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human)) | BDBM24566 (2-({4-chloro-6-[(2,3-dimethylphenyl)amino]pyrimidi...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | n/a | 1.62E+3 | n/a | n/a | n/a | n/a |
Consiglio Nazionale delle Ricerche | Assay Description The HepG2 cells were co-transfected with DNA construct containing PPAR-Gal4 chimeric receptor and Gal4-luciferase reporter. The luciferase activity w... | J Med Chem 51: 7768-76 (2008) Article DOI: 10.1021/jm800733h BindingDB Entry DOI: 10.7270/Q2CC0Z0D | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |