Found 35 hits Enz. Inhib. hit(s) with all data for entry = 50002267 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM36371
(5-(1H-indol-3-ylmethyl)-3-methyl-2-thioxo-4-Imidaz...)Show InChI InChI=1S/C13H13N3OS/c1-16-12(17)11(15-13(16)18)6-8-7-14-10-5-3-2-4-9(8)10/h2-5,7,11,14H,6H2,1H3,(H,15,18) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
Patents
| Article PubMed
| 1.14E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University
Curated by ChEMBL
| Assay Description Inhibition of IDO1 (unknown origin) |
Eur J Med Chem 138: 199-211 (2017)
Article DOI: 10.1016/j.ejmech.2017.06.039 BindingDB Entry DOI: 10.7270/Q2C25012 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50241727
((S)-2-amino-3-(1-methyl-1H-indol-3-yl)propanoic ac...)Show InChI InChI=1S/C12H14N2O2/c1-14-7-8(6-10(13)12(15)16)9-4-2-3-5-11(9)14/h2-5,7,10H,6,13H2,1H3,(H,15,16)/t10-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University
Curated by ChEMBL
| Assay Description Inhibition of IDO1 (unknown origin) |
Eur J Med Chem 138: 199-211 (2017)
Article DOI: 10.1016/j.ejmech.2017.06.039 BindingDB Entry DOI: 10.7270/Q2C25012 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50126144
(CHEMBL3629569 | US10155972, Compound NewLink 1 | U...)Show InChI InChI=1S/C18H22N2O/c21-18(13-6-2-1-3-7-13)10-16-14-8-4-5-9-15(14)17-11-19-12-20(16)17/h4-5,8-9,11-13,16,18,21H,1-3,6-7,10H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| n/a | n/a | 410 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University
Curated by ChEMBL
| Assay Description Inhibition of IFNgamma-induced IDO1 in human HeLa cells using L-tryptophan as substrate after 24 hrs |
Eur J Med Chem 138: 199-211 (2017)
Article DOI: 10.1016/j.ejmech.2017.06.039 BindingDB Entry DOI: 10.7270/Q2C25012 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50456430
(CHEMBL4205135)Show InChI InChI=1S/C14H9Cl2NO2/c15-10-3-1-9(2-4-10)8-17-12-7-11(16)5-6-13(12)19-14(17)18/h1-7H,8H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 6.08E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University
Curated by ChEMBL
| Assay Description Inhibition of IFNgamma-induced IDO1 in human HeLa cells using L-tryptophan as substrate after 24 hrs |
Eur J Med Chem 138: 199-211 (2017)
Article DOI: 10.1016/j.ejmech.2017.06.039 BindingDB Entry DOI: 10.7270/Q2C25012 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50456412
(CHEMBL4204527)Show InChI InChI=1S/C15H9ClFNO3/c16-10-3-6-13-12(8-10)18(15(20)21-13)14(19)7-9-1-4-11(17)5-2-9/h1-6,8H,7H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 6.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University
Curated by ChEMBL
| Assay Description Inhibition of IFNgamma-induced IDO1 in human HeLa cells using L-tryptophan as substrate after 24 hrs |
Eur J Med Chem 138: 199-211 (2017)
Article DOI: 10.1016/j.ejmech.2017.06.039 BindingDB Entry DOI: 10.7270/Q2C25012 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50456416
(CHEMBL4204643)Show InChI InChI=1S/C14H9ClFNO2/c15-10-4-5-13-12(7-10)17(14(18)19-13)8-9-2-1-3-11(16)6-9/h1-7H,8H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 9.75E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University
Curated by ChEMBL
| Assay Description Inhibition of IFNgamma-induced IDO1 in human HeLa cells using L-tryptophan as substrate after 24 hrs |
Eur J Med Chem 138: 199-211 (2017)
Article DOI: 10.1016/j.ejmech.2017.06.039 BindingDB Entry DOI: 10.7270/Q2C25012 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50456420
(CHEMBL4216081)Show InChI InChI=1S/C15H11ClFNO3/c16-10-3-6-14-12(7-10)18(15(20)21-14)8-13(19)9-1-4-11(17)5-2-9/h1-7,13,19H,8H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.02E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University
Curated by ChEMBL
| Assay Description Inhibition of IFNgamma-induced IDO1 in human HeLa cells using L-tryptophan as substrate after 24 hrs |
Eur J Med Chem 138: 199-211 (2017)
Article DOI: 10.1016/j.ejmech.2017.06.039 BindingDB Entry DOI: 10.7270/Q2C25012 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50456428
(CHEMBL4209018)Show InChI InChI=1S/C16H13ClN2O4/c1-22-12-4-2-3-10(7-12)9-18-15(20)19-13-8-11(17)5-6-14(13)23-16(19)21/h2-8H,9H2,1H3,(H,18,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.46E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University
Curated by ChEMBL
| Assay Description Inhibition of IFNgamma-induced IDO1 in human HeLa cells using L-tryptophan as substrate after 24 hrs |
Eur J Med Chem 138: 199-211 (2017)
Article DOI: 10.1016/j.ejmech.2017.06.039 BindingDB Entry DOI: 10.7270/Q2C25012 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50456427
(CHEMBL4208580)Show InChI InChI=1S/C15H12ClNO2/c16-12-6-7-14-13(10-12)17(15(18)19-14)9-8-11-4-2-1-3-5-11/h1-7,10H,8-9H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.79E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University
Curated by ChEMBL
| Assay Description Inhibition of IFNgamma-induced IDO1 in human HeLa cells using L-tryptophan as substrate after 24 hrs |
Eur J Med Chem 138: 199-211 (2017)
Article DOI: 10.1016/j.ejmech.2017.06.039 BindingDB Entry DOI: 10.7270/Q2C25012 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50456423
(CHEMBL4205040)Show InChI InChI=1S/C15H9ClFNO3/c16-10-3-6-14-12(7-10)18(15(20)21-14)8-13(19)9-1-4-11(17)5-2-9/h1-7H,8H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.07E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University
Curated by ChEMBL
| Assay Description Inhibition of IFNgamma-induced IDO1 in human HeLa cells using L-tryptophan as substrate after 24 hrs |
Eur J Med Chem 138: 199-211 (2017)
Article DOI: 10.1016/j.ejmech.2017.06.039 BindingDB Entry DOI: 10.7270/Q2C25012 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50456405
(CHEMBL4217799)Show InChI InChI=1S/C15H12FN3O/c16-11-7-5-10(6-8-11)9-14(20)19-13-4-2-1-3-12(13)18-15(19)17/h1-8H,9H2,(H2,17,18) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.27E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University
Curated by ChEMBL
| Assay Description Inhibition of IFNgamma-induced IDO1 in human HeLa cells using L-tryptophan as substrate after 24 hrs |
Eur J Med Chem 138: 199-211 (2017)
Article DOI: 10.1016/j.ejmech.2017.06.039 BindingDB Entry DOI: 10.7270/Q2C25012 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50456422
(CHEMBL4204542)Show InChI InChI=1S/C15H9Cl2NO3/c16-10-3-1-9(2-4-10)13(19)8-18-12-7-11(17)5-6-14(12)21-15(18)20/h1-7H,8H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.49E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University
Curated by ChEMBL
| Assay Description Inhibition of IFNgamma-induced IDO1 in human HeLa cells using L-tryptophan as substrate after 24 hrs |
Eur J Med Chem 138: 199-211 (2017)
Article DOI: 10.1016/j.ejmech.2017.06.039 BindingDB Entry DOI: 10.7270/Q2C25012 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50456415
(CHEMBL4214555)Show InChI InChI=1S/C14H9F2NO2/c15-10-3-1-2-9(6-10)8-17-12-7-11(16)4-5-13(12)19-14(17)18/h1-7H,8H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.85E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University
Curated by ChEMBL
| Assay Description Inhibition of IFNgamma-induced IDO1 in human HeLa cells using L-tryptophan as substrate after 24 hrs |
Eur J Med Chem 138: 199-211 (2017)
Article DOI: 10.1016/j.ejmech.2017.06.039 BindingDB Entry DOI: 10.7270/Q2C25012 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50456418
(CHEMBL1557295)Show InChI InChI=1S/C14H10FNO2/c15-11-5-3-4-10(8-11)9-16-12-6-1-2-7-13(12)18-14(16)17/h1-8H,9H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.08E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University
Curated by ChEMBL
| Assay Description Inhibition of IFNgamma-induced IDO1 in human HeLa cells using L-tryptophan as substrate after 24 hrs |
Eur J Med Chem 138: 199-211 (2017)
Article DOI: 10.1016/j.ejmech.2017.06.039 BindingDB Entry DOI: 10.7270/Q2C25012 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50456411
(CHEMBL4203649)Show InChI InChI=1S/C16H14N2O4/c1-21-12-8-6-11(7-9-12)10-17-15(19)18-13-4-2-3-5-14(13)22-16(18)20/h2-9H,10H2,1H3,(H,17,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.18E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University
Curated by ChEMBL
| Assay Description Inhibition of IFNgamma-induced IDO1 in human HeLa cells using L-tryptophan as substrate after 24 hrs |
Eur J Med Chem 138: 199-211 (2017)
Article DOI: 10.1016/j.ejmech.2017.06.039 BindingDB Entry DOI: 10.7270/Q2C25012 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50456417
(CHEMBL4213517)Show InChI InChI=1S/C14H10ClNO2/c15-11-7-5-10(6-8-11)9-16-12-3-1-2-4-13(12)18-14(16)17/h1-8H,9H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University
Curated by ChEMBL
| Assay Description Inhibition of IFNgamma-induced IDO1 in human HeLa cells using L-tryptophan as substrate after 24 hrs |
Eur J Med Chem 138: 199-211 (2017)
Article DOI: 10.1016/j.ejmech.2017.06.039 BindingDB Entry DOI: 10.7270/Q2C25012 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50456408
(CHEMBL4217258)Show InChI InChI=1S/C15H10ClNO3/c16-11-7-5-10(6-8-11)13(18)9-17-12-3-1-2-4-14(12)20-15(17)19/h1-8H,9H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.86E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University
Curated by ChEMBL
| Assay Description Inhibition of IFNgamma-induced IDO1 in human HeLa cells using L-tryptophan as substrate after 24 hrs |
Eur J Med Chem 138: 199-211 (2017)
Article DOI: 10.1016/j.ejmech.2017.06.039 BindingDB Entry DOI: 10.7270/Q2C25012 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50456433
(CHEMBL4216727)Show InChI InChI=1S/C15H10ClNO3/c16-11-5-3-4-10(8-11)13(18)9-17-12-6-1-2-7-14(12)20-15(17)19/h1-8H,9H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 4.93E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University
Curated by ChEMBL
| Assay Description Inhibition of IFNgamma-induced IDO1 in human HeLa cells using L-tryptophan as substrate after 24 hrs |
Eur J Med Chem 138: 199-211 (2017)
Article DOI: 10.1016/j.ejmech.2017.06.039 BindingDB Entry DOI: 10.7270/Q2C25012 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50456404
(CHEMBL4208059)Show InChI InChI=1S/C15H12FNO3/c16-11-7-5-10(6-8-11)13(18)9-17-12-3-1-2-4-14(12)20-15(17)19/h1-8,13,18H,9H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 4.93E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University
Curated by ChEMBL
| Assay Description Inhibition of IFNgamma-induced IDO1 in human HeLa cells using L-tryptophan as substrate after 24 hrs |
Eur J Med Chem 138: 199-211 (2017)
Article DOI: 10.1016/j.ejmech.2017.06.039 BindingDB Entry DOI: 10.7270/Q2C25012 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50456432
(CHEMBL4204366)Show InChI InChI=1S/C15H12ClNO3/c16-11-7-5-10(6-8-11)13(18)9-17-12-3-1-2-4-14(12)20-15(17)19/h1-8,13,18H,9H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 5.08E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University
Curated by ChEMBL
| Assay Description Inhibition of IFNgamma-induced IDO1 in human HeLa cells using L-tryptophan as substrate after 24 hrs |
Eur J Med Chem 138: 199-211 (2017)
Article DOI: 10.1016/j.ejmech.2017.06.039 BindingDB Entry DOI: 10.7270/Q2C25012 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50456424
(CHEMBL4212289)Show InChI InChI=1S/C15H10FNO3/c16-11-7-5-10(6-8-11)13(18)9-17-12-3-1-2-4-14(12)20-15(17)19/h1-8H,9H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 5.31E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University
Curated by ChEMBL
| Assay Description Inhibition of IFNgamma-induced IDO1 in human HeLa cells using L-tryptophan as substrate after 24 hrs |
Eur J Med Chem 138: 199-211 (2017)
Article DOI: 10.1016/j.ejmech.2017.06.039 BindingDB Entry DOI: 10.7270/Q2C25012 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50456419
(CHEMBL4209170)Show InChI InChI=1S/C15H11Cl2NO3/c16-10-3-1-2-9(6-10)13(19)8-18-12-7-11(17)4-5-14(12)21-15(18)20/h1-7,13,19H,8H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 6.09E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University
Curated by ChEMBL
| Assay Description Inhibition of IFNgamma-induced IDO1 in human HeLa cells using L-tryptophan as substrate after 24 hrs |
Eur J Med Chem 138: 199-211 (2017)
Article DOI: 10.1016/j.ejmech.2017.06.039 BindingDB Entry DOI: 10.7270/Q2C25012 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50456426
(CHEMBL4205684)Show InChI InChI=1S/C15H11Cl2NO3/c16-10-3-1-9(2-4-10)13(19)8-18-12-7-11(17)5-6-14(12)21-15(18)20/h1-7,13,19H,8H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 6.27E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University
Curated by ChEMBL
| Assay Description Inhibition of IFNgamma-induced IDO1 in human HeLa cells using L-tryptophan as substrate after 24 hrs |
Eur J Med Chem 138: 199-211 (2017)
Article DOI: 10.1016/j.ejmech.2017.06.039 BindingDB Entry DOI: 10.7270/Q2C25012 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50456421
(CHEMBL4209417)Show InChI InChI=1S/C15H9Cl2NO3/c16-10-3-1-2-9(6-10)13(19)8-18-12-7-11(17)4-5-14(12)21-15(18)20/h1-7H,8H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 7.66E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University
Curated by ChEMBL
| Assay Description Inhibition of IFNgamma-induced IDO1 in human HeLa cells using L-tryptophan as substrate after 24 hrs |
Eur J Med Chem 138: 199-211 (2017)
Article DOI: 10.1016/j.ejmech.2017.06.039 BindingDB Entry DOI: 10.7270/Q2C25012 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50241727
((S)-2-amino-3-(1-methyl-1H-indol-3-yl)propanoic ac...)Show InChI InChI=1S/C12H14N2O2/c1-14-7-8(6-10(13)12(15)16)9-4-2-3-5-11(9)14/h2-5,7,10H,6,13H2,1H3,(H,15,16)/t10-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 7.73E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University
Curated by ChEMBL
| Assay Description Inhibition of IFNgamma-induced IDO1 in human HeLa cells using L-tryptophan as substrate after 24 hrs |
Eur J Med Chem 138: 199-211 (2017)
Article DOI: 10.1016/j.ejmech.2017.06.039 BindingDB Entry DOI: 10.7270/Q2C25012 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50456407
(CHEMBL4212295)Show InChI InChI=1S/C15H12ClNO3/c16-11-5-3-4-10(8-11)13(18)9-17-12-6-1-2-7-14(12)20-15(17)19/h1-8,13,18H,9H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 8.06E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University
Curated by ChEMBL
| Assay Description Inhibition of IFNgamma-induced IDO1 in human HeLa cells using L-tryptophan as substrate after 24 hrs |
Eur J Med Chem 138: 199-211 (2017)
Article DOI: 10.1016/j.ejmech.2017.06.039 BindingDB Entry DOI: 10.7270/Q2C25012 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50456414
(CHEMBL4210797)Show InChI InChI=1S/C14H9ClFNO2/c15-10-3-1-9(2-4-10)8-17-12-7-11(16)5-6-13(12)19-14(17)18/h1-7H,8H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 8.08E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University
Curated by ChEMBL
| Assay Description Inhibition of IFNgamma-induced IDO1 in human HeLa cells using L-tryptophan as substrate after 24 hrs |
Eur J Med Chem 138: 199-211 (2017)
Article DOI: 10.1016/j.ejmech.2017.06.039 BindingDB Entry DOI: 10.7270/Q2C25012 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50456429
(CHEMBL4216191)Show InChI InChI=1S/C14H9NO3/c16-13(10-6-2-1-3-7-10)15-11-8-4-5-9-12(11)18-14(15)17/h1-9H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 9.05E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University
Curated by ChEMBL
| Assay Description Inhibition of IFNgamma-induced IDO1 in human HeLa cells using L-tryptophan as substrate after 24 hrs |
Eur J Med Chem 138: 199-211 (2017)
Article DOI: 10.1016/j.ejmech.2017.06.039 BindingDB Entry DOI: 10.7270/Q2C25012 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50456403
(CHEMBL4213252)Show SMILES [O-][N+](=O)c1ccc2oc(=O)n(Cc3ccc(Cl)cc3)c2c1 Show InChI InChI=1S/C14H9ClN2O4/c15-10-3-1-9(2-4-10)8-16-12-7-11(17(19)20)5-6-13(12)21-14(16)18/h1-7H,8H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 9.94E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University
Curated by ChEMBL
| Assay Description Inhibition of IFNgamma-induced IDO1 in human HeLa cells using L-tryptophan as substrate after 24 hrs |
Eur J Med Chem 138: 199-211 (2017)
Article DOI: 10.1016/j.ejmech.2017.06.039 BindingDB Entry DOI: 10.7270/Q2C25012 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50456425
(CHEMBL4208319)Show SMILES [O-][N+](=O)c1ccc2oc(=O)n(Cc3cccc(F)c3)c2c1 Show InChI InChI=1S/C14H9FN2O4/c15-10-3-1-2-9(6-10)8-16-12-7-11(17(19)20)4-5-13(12)21-14(16)18/h1-7H,8H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 9.98E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University
Curated by ChEMBL
| Assay Description Inhibition of IFNgamma-induced IDO1 in human HeLa cells using L-tryptophan as substrate after 24 hrs |
Eur J Med Chem 138: 199-211 (2017)
Article DOI: 10.1016/j.ejmech.2017.06.039 BindingDB Entry DOI: 10.7270/Q2C25012 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50456409
(CHEMBL4205092)Show InChI InChI=1S/C15H13FN2O2/c16-11-7-5-10(6-8-11)14(19)9-18-13-4-2-1-3-12(13)17-15(18)20/h1-8,14,19H,9H2,(H,17,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 9.99E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University
Curated by ChEMBL
| Assay Description Inhibition of IFNgamma-induced IDO1 in human HeLa cells using L-tryptophan as substrate after 24 hrs |
Eur J Med Chem 138: 199-211 (2017)
Article DOI: 10.1016/j.ejmech.2017.06.039 BindingDB Entry DOI: 10.7270/Q2C25012 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50456431
(CHEMBL1444923)Show InChI InChI=1S/C15H13NO2/c17-15-16(11-10-12-6-2-1-3-7-12)13-8-4-5-9-14(13)18-15/h1-9H,10-11H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University
Curated by ChEMBL
| Assay Description Inhibition of IFNgamma-induced IDO1 in human HeLa cells using L-tryptophan as substrate after 24 hrs |
Eur J Med Chem 138: 199-211 (2017)
Article DOI: 10.1016/j.ejmech.2017.06.039 BindingDB Entry DOI: 10.7270/Q2C25012 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50456410
(CHEMBL4207877)Show InChI InChI=1S/C15H11ClN2O4/c1-21-11-5-3-10(4-6-11)17-14(19)18-12-8-9(16)2-7-13(12)22-15(18)20/h2-8H,1H3,(H,17,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University
Curated by ChEMBL
| Assay Description Inhibition of IFNgamma-induced IDO1 in human HeLa cells using L-tryptophan as substrate after 24 hrs |
Eur J Med Chem 138: 199-211 (2017)
Article DOI: 10.1016/j.ejmech.2017.06.039 BindingDB Entry DOI: 10.7270/Q2C25012 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50456413
(CHEMBL4208865)Show InChI InChI=1S/C15H10FNO3/c16-11-7-5-10(6-8-11)9-14(18)17-12-3-1-2-4-13(12)20-15(17)19/h1-8H,9H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University
Curated by ChEMBL
| Assay Description Inhibition of IFNgamma-induced IDO1 in human HeLa cells using L-tryptophan as substrate after 24 hrs |
Eur J Med Chem 138: 199-211 (2017)
Article DOI: 10.1016/j.ejmech.2017.06.039 BindingDB Entry DOI: 10.7270/Q2C25012 |
More data for this Ligand-Target Pair | |
Indoleamine 2,3-dioxygenase 1
(Homo sapiens (Human)) | BDBM50456406
(CHEMBL4203984)Show InChI InChI=1S/C14H11FN2O2/c15-10-3-1-2-9(6-10)8-17-12-7-11(16)4-5-13(12)19-14(17)18/h1-7H,8,16H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University
Curated by ChEMBL
| Assay Description Inhibition of IFNgamma-induced IDO1 in human HeLa cells using L-tryptophan as substrate after 24 hrs |
Eur J Med Chem 138: 199-211 (2017)
Article DOI: 10.1016/j.ejmech.2017.06.039 BindingDB Entry DOI: 10.7270/Q2C25012 |
More data for this Ligand-Target Pair | |